association	dataset	threshold value	standardized value
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Breast cancer (survival)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4422
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930444
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6106
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.22385
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15328_KO_Uxt_SRP274268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17124
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086637
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREBBP	ENCODE Transcription Factor Targets	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95593
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042713
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1659
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871035
CID-2745687	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
duplication of phalanx of toe	HPO Gene-Disease Associations	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.596036
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.596947
WC-59-RG09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283467
Centriole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CD-47-YL43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459478
IMR-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51483
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704733
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20476
membrane	GO Cellular Component Annotations 2015	1.0	null
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22135
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49197
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81386
6693_PPP3CB_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.530837
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31045
CHEK2_knockdown_84_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77178
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21248
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Agranular insular area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15276
FOXM1-25889361-OE33-AND-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77575
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249977
Accessory Spleen	DisGeNET Gene-Disease Associations	1.0	null
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252576
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22166
arrhinencephaly	HPO Gene-Disease Associations	1.0	null
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13563
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Patau syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
duplication of phalanx of hallux	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33401
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935118
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23418
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11802
homozygous	GeneRIF Biological Term Annotations	1.0	null
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15806
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04647
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.285316
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Hydrolethalus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.649
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.384
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06284
myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180652
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68208
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34678
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132931
Perturb_16086_KO_Bap1_SRP270239	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.21025
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957993
Perturb_4346_KO_Tln1_SRP378238	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54521
Perturb_8708_KD_Irf2_SRP193480	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41733
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4488
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00676
culture condition	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374993
abnormality of the fourth ventricle	HPO Gene-Disease Associations	1.0	null
BICR22	DepMap CRISPR Gene Dependency	1.0	3.83711
Hydrolethalus Syndrome 1	DisGeNET Gene-Disease Associations	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17688
Anophthalmos	DisGeNET Gene-Disease Associations	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871973
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4946
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68242
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984544
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30862
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089952
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
BC-51-ME52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350873
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6352
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.909
Perturb_18554_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.41708
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30321
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94053
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062964
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15215
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31221
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8535
M059J	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4468
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17797
Perturb_9496_KO_Bscl2_SRP345421	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01162
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53634
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369997
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225267
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75117
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FOXM1	ChEA Transcription Factor Targets	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-2.39847
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8858
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251521
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488608
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.368536
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64942
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34633
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05303
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11207
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87979
Perturb_15116_KD_Rtn4_SRP278924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502483
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7268
Perturb_50_KO_Kat6a_SRP215863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.495
mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.355183
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20117
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58128
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52056
osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22937
PMC6053425-41467_2018_5258_MOESM20_ESM.xlsx-DREAM_MMBFoxM1_targets-Unnamed_1_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83044
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8277
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4401
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.12357
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915415
Perturb_5282_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.36597
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516497
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0738
HEL	CCLE Cell Line Gene CNV Profiles	1.0	1.97164
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89865
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.545016
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Septooptic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65061
PMC7672319-mmc3.xlsx-DREAM_MSigDB62-FISCHER_DREAM_TARGETS_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06593
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945141
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.993
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18322
abnormality of the tracheobronchial system	HPO Gene-Disease Associations	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.32899
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52484
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45907
GSE132369,GSE132371_4_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.32862
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
SKPNDW	DepMap CRISPR Gene Dependency	1.0	2.69607
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12125067-10157_2025_2629_MOESM3_ESM.docx-9-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11773_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.24303
19351829-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
4,4'-Dimethoxybenzil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6208
pc3	HPA Cell Line Gene Expression Profiles	1.0	1.48482
duplication of hand bones	HPO Gene-Disease Associations	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906854
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.76
Dandy-Walker Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18169
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2488
Perturb_15680_KD_Srsf9_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.48432
cilium organization	GO Biological Process Annotations 2023	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09597
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19028
low-set, posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26474
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.869683
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08271
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0961
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186269
Perturb_1018_Mut_Tspan2_SRP285017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.27489
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.2094
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04753
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03191
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.89463
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.03084
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50605
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliopathies	WikiPathways Pathways 2024	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-44-UR36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201204
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34011
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227487
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45316
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12537
spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625465
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.59195
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06212
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432225
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6433297-pbio.3000178.s012.xlsx-DREAM_targets-BUB1B_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14589
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7031
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3595
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21602
Perturb_16764_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.0877
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.742453
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320663
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
aplasia/hypoplasia involving bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5578
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891536
burkitt lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21365
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48432
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79081
Perturb_4521_KO_Mapk1/Mapk3_SRP281895	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.40036
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39733
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09939
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16586
Lymphoblast	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57949
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.851629
posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7746
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6909
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964259
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02606
GSE109530,GSE109531_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13285
HCMV_TB40E_24Hour_19951172_GSE14816	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.29185
Premature Birth	DisGeNET Gene-Phenotype Associations	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856203
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00509
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.801042
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_4573_KO_Pwwp2a/Pwwp2b_SRP255880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50106
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.52792
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403613
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983704
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47043
CEBPB_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH82	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67019
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18799
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.12082
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11742
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
6794_PRPF38A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.598087
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85555
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.69971
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1703
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09399
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.455
PANC1	CCLE Cell Line Gene Expression Profiles	1.0	1.67779
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4843
Trihydroxyisoflavone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.576528
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.82907
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17809
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05656
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44944
Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX19A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81524
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1563
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04638
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22605
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61813
Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
abnormality of the lip	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02902
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110425
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898595
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905821
PTEN_KD_GDS4759_337_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.749077
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14873
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.33444
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02111
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35394
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927537
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14765
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881232
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933064
mode of inheritance	HPO Gene-Disease Associations	1.0	null
b-lymphoblastoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160877
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5915
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277225
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.07095
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831702
MET_knockout_249_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.44341
etiolated plant tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.891798
1583_CHMP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513115
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500664
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063354
BF-10-IO69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355125
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IOMMLEE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02402
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2718
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880117
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063633
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905177
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.96335
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.542764
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258988
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15582
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83257
SW1463	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21218
caco2	HPA Cell Line Gene Expression Profiles	-1.0	-1.45932
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1246
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12827
TE-26-XS06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265143
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76223
9482_UBA52_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.679712
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02248
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98606
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.51482
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31494
Perturb_12673_KD_Mitf_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.61525
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976515
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hirschsprung Disease	DisGeNET Gene-Disease Associations	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869785
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.75632
Perturb_9718_OE_Wt1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.08407
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.958018
Perturb_2378_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.5691
Familial Aplasia Of The Vermis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_20_OE_Smarca5_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.3271
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31145
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bifid uterus	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86232
EC-01-PH79_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375294
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02568
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
BIN67	DepMap CRISPR Gene Dependency	1.0	2.08415
PATU8902	CCLE Cell Line Gene Expression Profiles	1.0	1.62978
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33656
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.221378
hsa-miR-938	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212838
GI1	DepMap CRISPR Gene Dependency	1.0	2.79508
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03839
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
abdominal wall defect	HPO Gene-Disease Associations	1.0	null
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22849
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STL336112	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.67
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384971
PAX3_01_27	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60029
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.93282
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31137
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10226
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895752
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.705144
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.971221
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46064
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849135
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12741
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.625711
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831315
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02482
Perturb_11850_KO_Unc119b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10652
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49678
Autosomal recessive polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.830979
PMC7264249-41389_2020_240_MOESM2_ESM.xls-Tab10_siG2-Down_G2_target_genes-Table_10_Down-regulated_genes_after_GLIS2_knockdown_and_adjacent_to_GLIS2_binding_sites_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07451
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Congenital Cerebral Hernia	DisGeNET Gene-Disease Associations	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-MYBL2_targets_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57338
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0506
osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A388	DepMap CRISPR Gene Dependency	1.0	2.60299
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02807
Perturb_12568_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
mortality/aging	HPO Gene-Disease Associations	1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.286
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92959
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888574
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.92718
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14769
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	1.59108
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34013
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hydrolethalus syndrome protein 1	InterPro Predicted Protein Domain Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7501-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06875
lymph node	HPA Tissue Gene Expression Profiles	1.0	0.847482
KYM1	DepMap CRISPR Gene Dependency	1.0	2.18315
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	2.10234
GSE103068_5_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7981_KD_Stag2_SRP191444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72723
interleukin-27 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266042
Gingival Cleft	DisGeNET Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074969
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26647
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6060_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.62847
Perturb_12569_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102223
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397793
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.227
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-00-BX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372435
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21917
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11898
Perturb_6295_KO_KRT17_SRP314436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Bifid Nose	DisGeNET Gene-Disease Associations	1.0	null
FA-80-DR66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21379
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20782
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22926
AE-04-SN76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.567627
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.50423
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17197
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01282
GSE67266_5_v_1_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38455
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.76868
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305223
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.659808
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.632922
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18212
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17197
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061112
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930223
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57722
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24464
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48819
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.943902
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.507
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598494
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02972
A2058	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3528
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.05816
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61967
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Hypospadias	DisGeNET Gene-Disease Associations	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.05816
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31436
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3341
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39217
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46104
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21919
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20837
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354887
germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774004
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15347
abnormality of neuronal migration	HPO Gene-Disease Associations	1.0	null
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.523
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864492
embryonic growth retardation	IMPC Knockout Mouse Phenotypes	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6126
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
KH7	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.69
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08971
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
commensal bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.119018
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04289
cleft upper lip	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05698
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.576348
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84185
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5882
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
Imperforate anus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.696306
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28385
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22732
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18883
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827644
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.752
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22224
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04877
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09724
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75986
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24333
Adrenal Gland Pheochromocytoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56178
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31393
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00155
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.15944
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53387
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928519
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
liminal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24832
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32988
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3689a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
aplasia/hypoplasia involving bones of the upper limbs	HPO Gene-Disease Associations	1.0	null
cilium	GO Cellular Component Annotations 2025	1.0	null
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3672
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Joubert syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
mantle zone of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24752
TALL1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34828
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7595
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.93671
E2F4	ChEA Transcription Factor Targets	1.0	null
Perturb_1265_KO_Jak1_SRP214595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35703
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.735
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.63083
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16452
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.663
PMC11031166-SAG-2302-87_0_Appendix_1_SG_IHDS_(569_genes)_Final_List.xlsx-AP1-Genes_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10607
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S9-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2082
Perturb_13769_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.65822
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.17399
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876624
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.654262
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918217
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14021
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297432
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.785807
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19104
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.815105
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37624
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8421
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467564
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72455
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2242
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02955
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884675
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91137
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2594
Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
burkitt lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.842982
AGS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18777
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51347
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221674
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Chromosome 18p deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Perturb_5149_KO_Thap11_ERP126456	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.04943
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40126
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.464397
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.963053
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931956
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18775
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882782
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946275
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.769804
hydrolethalus syndrome	OMIM Gene-Disease Associations	1.0	null
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15094
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13582
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052081
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31618
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01702
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00868
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
Arhinencephaly	DisGeNET Gene-Disease Associations	1.0	null
adrenal gland dysgenesis	HPO Gene-Disease Associations	1.0	null
cryptorchidism	HPO Gene-Disease Associations	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02266
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23814
Laryngomalacia	DisGeNET Gene-Disease Associations	1.0	null
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20775
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.21659
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77735
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18756
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.70854
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258513
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61249
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3382
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08046
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31047
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39425
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86006
GSE202434,GSE202438_3_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41622
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07927
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81304
PJ34	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01812
NB1643	DepMap CRISPR Gene Dependency	1.0	4.14755
CA-68-TC79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414081
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
AD-52-UZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235688
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4365
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68661
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5698
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tirofiban	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.85031
Perturb_15753_KO_Ezh2_SRP096837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46K-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.00902
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9252
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14897
cilium assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8927
Perturb_218_KO_Uba6_SRP389127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.89659
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97333
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853818
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2786
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828484
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14938_KD_Ptbp1_SRP053095	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.70569
Perturb_10317_KO_miR25_SRP188485	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.80929
Perturb_16923_KO_miR26a1/miR26a2/miR26b_SRP216065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.53008
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2251
inner CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79869
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878869
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04005
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21043
Hernia, Diaphragmatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10797
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67405
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14781
time of death	HPO Gene-Disease Associations	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ramos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398357
LS180	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57038
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14818
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R8-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13989_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.4683
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1975
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841661
OB-17-DQ74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235117
SB-75-TY18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21201
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12009
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944837
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83156
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4141
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Submucous Cleft Of Hard Palate	DisGeNET Gene-Disease Associations	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSK-923295	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.94
MDAMB231	CCLE Cell Line Gene Expression Profiles	1.0	1.4274
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358208
NCIH1341	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02522
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.82343
lung_3e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.898154
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1244
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.22949
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15503
Pictilisib	DeepCoverMOA Drug Mechanisms of Action	1.0	1.64
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.828622
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03923
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6053425-41467_2018_5258_MOESM20_ESM.xlsx-DREAM_MMBFoxM1_targets-Fischer_M_et_al_Nucleic_Acids_Res_2016_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07563
nucleus	GO Cellular Component Annotations 2015	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27042
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34499
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21918
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27229
GSE149035_1_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XEN445	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236695
KDM5B	ChEA Transcription Factor Targets	1.0	null
EVI5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31779
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48415
micrognathia	HPO Gene-Disease Associations	1.0	null
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14102
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.290815
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.961137
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.283
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.98969
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4006
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66446
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.081384
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23591
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11587
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22657
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the amniotic fluid	HPO Gene-Disease Associations	1.0	null
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
Chromosome Aberrations	HuGE Navigator Gene-Phenotype Associations	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Actin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
TOV21G	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.40745
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14947_KD_Parp1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.57814
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.825522
SIX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13011
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947784
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52135
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
prolonged PQ interval	IMPC Knockout Mouse Phenotypes	1.0	null
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01493
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15302
AZD8055	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.1
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092219
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34384
Ulnar Polydactyly Of Fingers	DisGeNET Gene-Disease Associations	1.0	null
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.960027
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.214
Rhodanine derivative38	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
series	GeneRIF Biological Term Annotations	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Holoprosencephaly 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621728
PMC12441061-10157_2025_2675_MOESM2_ESM.docx-9-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
RVH421	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68944
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I4-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80951
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314563
Color Blindness	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999297
abnormality of the urethra	HPO Gene-Disease Associations	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51266
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207611,GSE207612_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WB-82-EL69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349942
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55398
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00194
NPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35045
substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.250311
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32629
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25016
Perturb_10652_KD_Syncrip_SRP065017	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.91588
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565631
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
VAChT_KD_GDS4325_361_mouse_Heart from C57BL/6 males	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912685
6416_PLBD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.724952
PMC6786946-NIHMS1535503-supplement-3.xlsx-SAT1_2_0x-FOXM1_genes_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86387
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.0538
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.882236
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44618
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893285
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.32138
FD-15-HD09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336034
abnormality of the phalanges of the toes	HPO Gene-Disease Associations	1.0	null
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
KATOIII	CCLE Cell Line Gene CNV Profiles	1.0	1.62106
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06576
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3348
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.029641
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2082
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959689
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18999
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47864
Polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
EE-01-DO31_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308374
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868635
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1048
Lung squamous cell carcinoma_LUSC_TCGA-21-1072-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Upregulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08673
Perturb_5252_KO_Klf2/Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GD-59-OG21_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.652699
LN443	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24042
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9441
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04321
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.96449
Sarcoma_SARC_TCGA-DX-A3UF-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99429
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63721
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02025
dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510599
aplasia/hypoplasia of the  cerebellar vermis	HPO Gene-Disease Associations	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
ASXL1	ChEA Transcription Factor Targets	1.0	null
Perturb_13761_KO_Hotair_SRP026100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76883
Perturb_15851_KO_RbpJ_SRP165224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35808
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3124
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30659
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.490944
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497657
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29444
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530316
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
abnormality of the cerebellar vermis	HPO Gene-Disease Associations	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61513
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0745
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66955
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08117
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.56901
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06327
abnormal embryo size	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16461
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.72033
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.684547
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08259
abnormal lung lobation	HPO Gene-Disease Associations	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7073
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71829
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941643
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15562
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841259
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47888
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691384
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00758
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44495
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20178
Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-01-BR68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357834
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2926
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.11882
PC-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91183
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.496
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908456
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939934
Cleft In Skull Base	DisGeNET Gene-Phenotype Associations	1.0	null
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19716
clinicopathologic	GeneRIF Biological Term Annotations	1.0	null
dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052429
MOLM13	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.12568
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22415
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.09543
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.354499
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70721
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4044
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19694
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3068_KO_Apof_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.46234
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282132
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10939
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091736
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14022
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13681
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
anus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374438
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49208
Inflammation	CTD Gene-Disease Associations	1.0	1.54281
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32185
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung Diseases	CTD Gene-Disease Associations	1.0	1.20816
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94836
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
UTP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05703
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19054
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03285
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76108
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.26542
dermatomyositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.363347
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.58536
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
Proximal Tibial Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07975
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01193
Cerebellar Vermis Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31542
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48265
Perturb_5042_Mut_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.22862
Dandy-Walker syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
reticulosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.688692
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03391
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52749
SNU1196	DepMap CRISPR Gene Dependency	1.0	2.56455
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17709
Pheochromocytoma	DisGeNET Gene-Disease Associations	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
abnormality of upper lip	HPO Gene-Disease Associations	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8404
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972552
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-80-DI95_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.619024
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17484
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80024
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5248
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11242
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1263_KO_Mll3_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.44852
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045334
14737219-CSRgenes	GeneSigDB Published Gene Signatures	1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.25053
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068605
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14616
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840334
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11085
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27119
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962626
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.41087
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.69046
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368776
Prominent Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67781
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30444
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04281
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.962939
abnormality of the hard palate	HPO Gene-Disease Associations	1.0	null
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764468
cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10977
Isolated growth hormone deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.839705
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01933
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Smith-Lemli-Opitz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924962
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75738
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999201
abnormal embryo turning	MGI Mouse Phenotype Associations 2023	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-Y9YA_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248187
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1967
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39581
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.600644
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1456
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20181
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929149
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.73463
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047032
talipes	HPO Gene-Disease Associations	1.0	null
hsa-miR-192-5p	MiRTarBase microRNA Targets	1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64705
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.099829
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882751
Coloboma Of Iris	DisGeNET Gene-Disease Associations	1.0	null
PMC12125067-10157_2025_2629_MOESM3_ESM.docx-5-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15189
Agenesis	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tacrine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838848
Perturb_11842_KO_Stra6l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.97042
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972491
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981093
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75969
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
SYK_druginhibition_281_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.23283
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891423
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71691
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581119
polymyalgia rheumatica	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253479
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32633
GSE203158_1_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12441061-10157_2025_2675_MOESM2_ESM.docx-8-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_17824_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.52206
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05345
postaxial hand polydactyly	HPO Gene-Disease Associations	1.0	null
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03025
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39569
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CMK86	CCLE Cell Line Gene CNV Profiles	1.0	1.7897
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03365
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38041
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16537
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.89307
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03612
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280604
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20932
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01075
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944174
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483637
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	1.0	null
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18408
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal embryo turning	IMPC Knockout Mouse Phenotypes	1.0	null
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17996
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284244
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.121
abnormality of lower limb bone	HPO Gene-Disease Associations	1.0	null
osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484376
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064459
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29846
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48509
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04167
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068434
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29457
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02526
SNCA_KO_GDS4153_445_mouse_Striatum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5918
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
missense	GeneRIF Biological Term Annotations	1.0	null
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19767
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.96178
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL200403	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.15
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.837472
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868961
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36467
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4738
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01606
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the septum pellucidum	HPO Gene-Disease Associations	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
IA-27-CK10_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283389
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CI-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32751
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898938
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03932
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20337
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059432
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
KE39	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51166
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00608
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06384
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10273
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.95243
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994895
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948243
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42645
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09222
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958845
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Broad Neck	DisGeNET Gene-Phenotype Associations	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23347
ciliary cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.444878
aplasia/hypoplasia of the tibia	HPO Gene-Disease Associations	1.0	null
cerebellar vermis hypoplasia	HPO Gene-Disease Associations	1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00036
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10265
EZH2	ENCODE Transcription Factor Targets	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9944
Abnormality Of Cardiovascular System Morphology	DisGeNET Gene-Disease Associations	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73991
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.11
Perturb_11798_KO_Entpd8_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.15803
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15577
anencephaly	HPO Gene-Disease Associations	1.0	null
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10286_KO_Ypel3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08521
SR 11237	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.117021
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apical hook	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07221
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.093
EF-99-HJ48_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364724
Perturb_11416_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5382
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9839
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866604
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.769804
Perturb_5216_KO_Bap1_SRP162521	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.31895
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043137
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.919071
EC-71-PH39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278433
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256913
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32814
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx BloodVessel 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-11.077
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236506
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20741
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17312
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06281
OE-18-ZX28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212119
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07994
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.391537
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J4-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155512
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
PMC5503541-oncotarget-08-38399-s003.docx-1-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
Oral Cleft	DisGeNET Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.034
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7384
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43842
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498343
SLR25	Achilles Cell Line Gene Essentiality Profiles	1.0	1.42668
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352914
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66876
vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371477
abnormality of globe location	HPO Gene-Disease Associations	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236541
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.44418
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Primary microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980138
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01218
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.41478
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.397811
vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527139
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64895
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09926
Perturb_13146_Mut_Atrx_SRP194170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40433
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18747
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72476
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
cerebellar cyst	HPO Gene-Disease Associations	1.0	null
b-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166516
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hernia	HPO Gene-Disease Associations	1.0	null
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
MTFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07894
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16069
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33524
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17645
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.03983
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842048
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8646
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378748
AC-43-ZC52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208153
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56622
dandy-walker malformation	HPO Gene-Disease Associations	1.0	null
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-ARGFX_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365942
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130842
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.856557
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34714
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62098
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07796
Abnormal Lung Lobation	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864783
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61026
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.566821
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084748
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20082
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.789796
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.08224
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51934
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.647512
Perturb_11076_KO_Cnot1_ERP110668	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.69154
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39305
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227968
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.494022
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16083_KO_Hoxa9_SRP090515	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.66978
C14orf1	Pathway Commons Protein-Protein Interactions	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4294
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.940393
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861748
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69524
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995965
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00092
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.484
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046714
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90633
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.87847
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5671
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43676
Joubert syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31772
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16966
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853818
PMC12612227-41523_2025_836_MOESM1_ESM.pdf-21-L3MBTL3_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00294
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.51594
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9776
RUNX1	ChEA Transcription Factor Targets	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24021
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246846
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.266764
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.934992
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316854
hypospadias	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055592
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.979774
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.920344
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.05816
Perturb_9563_KO_Ogt_SRP110508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.80524
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO704	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34693
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23277
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
UA-39-TN76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.659786
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506488
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.131276
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01234
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0184
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
agenesis of corpus callosum	HPO Gene-Disease Associations	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Visual epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05402
COACH syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49597
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980526
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580017
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SKNO1	Achilles Cell Line Gene Essentiality Profiles	1.0	3.01373
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17197
Perturb_3779_KD_NFYA_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59989
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.40236
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713701
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06289
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476076
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20072
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21004
RD	DepMap CRISPR Gene Dependency	1.0	6.12512
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0372
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19781
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36604
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.27883
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03326
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4341
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836415
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83146
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443216
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2475
BD-48-ZT65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221231
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208007
Hydrolethalus syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.673
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38937
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83331
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91215
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	3.09246
Blonanserin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.37
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.993842
Lung squamous cell carcinoma_LUSC_TCGA-22-4599-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7328
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Cardiac tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41345
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.661594
CE-03-YQ91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303263
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10033
polydactyly	HPO Gene-Disease Associations	1.0	null
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.122
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.053974
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988114
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73295
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940056
cilium	GO Cellular Component Annotations 2023	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.61
Helam	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66342
GSE203158_12_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	1.83079
HT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51634
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.05816
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26836
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Centrosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37624
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.864083
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-0.944338
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7731
Perturb_4953_KO_Zbtb2_ERP125292	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.37404
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55751
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24794
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04473
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108732
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18867
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223008_5_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705993
Perturb_13358_KD_Irf1_SRP234803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4495
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894543
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02972
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.221
Perturb_15670_KD_Sf3a1_SRP043160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46433
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438039
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41156
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
HA-32-YH61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216366
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38131
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850346
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11203
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.41143
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5588
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24116
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01499
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861068
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32898
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14192
actinomycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.608494
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.691758
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.09262
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825884
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13208_KO_Foxd3_SRP060372	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.6516
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925597
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15264
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47895
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
positional foot deformity	HPO Gene-Disease Associations	1.0	null
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10135
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29917
Perturb_16739_KO_Gcn5_SRP271119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.44378
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85034
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918467
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB453	Achilles Cell Line Gene Essentiality Profiles	1.0	2.07856
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37063
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5119
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084207
Prostate adenocarcinoma_PRAD_TCGA-VN-A88N-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4220_ITFG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.50499
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.825265
Perturb_14569_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the cardiac septa	HPO Gene-Disease Associations	1.0	null
Perturb_5251_KO_Klf2_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512019
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.22396
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052501
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047406
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59796
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988148
2313_DNM2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.534227
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38596
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	2.18693
SLR20	CCLE Cell Line Gene Expression Profiles	1.0	2.2897
HEYA8	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09285
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371619
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18009
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67209
Orofaciodigital syndrome IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.245
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84757
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72813
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06766
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.72972
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934885
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.728898
PMC8160578-JCB_202009147_TableS4.xlsx-MYBL2_targets-Genes_n_532_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.41028
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883369
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.877
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865524
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34036
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398387
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04239
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974617
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.2487
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
OE-89-FS84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261276
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836849
Mental Retardation	DisGeNET Gene-Disease Associations	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-DREAM_target_genes_KCNIP3	Rummagene Transcription Factor Associations 2026	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0711
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852791
cleft in skull base	HPO Gene-Disease Associations	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
CAL-12T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4695
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844257
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25246
TA-20-FO62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227313
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47956
Adrenal Gland Dysgenesis	DisGeNET Gene-Phenotype Associations	1.0	null
GSE188458_2_v_0_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23942
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03704
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02449
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26449
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02118
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998305
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631527
Perturb_15736_KO_Meis1/Meis2_ERP122071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23003
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28521
DB-56-XL71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202171
same	GeneRIF Biological Term Annotations	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45292
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00293
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1087
brain	GTEx Tissue Gene Expression Profiles	1.0	1.181
Perturb_11818_KO_Nudt19_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.02701
Abnormal Vagina Morphology	DisGeNET Gene-Phenotype Associations	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.748081
BF-94-CQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256228
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219619
growth delay	HPO Gene-Disease Associations	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-64-KC49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.37613
Perturb_14445_KO_Mtor_SRP144775	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58785
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23666
Perturb_2379_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.8291
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.968
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24792
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08242
aplasia/hypoplasia of the extremities	HPO Gene-Disease Associations	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGFBR1_knockdown_102_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61098
abnormality of prenatal development or birth	HPO Gene-Disease Associations	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420863
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30231
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.192
Ciliary transition fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03631
SW48	DepMap CRISPR Gene Dependency	1.0	6.53612
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.63993
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21433
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66627
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18867
Perturb_13198_KO_Dax1_ERP123502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.4206
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-79-AG41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20647
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32335
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.482921
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08619
BD-85-GY20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284081
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39763
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04449
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847984
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07488
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1	DepMap CRISPR Gene Dependency	1.0	8.74009
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1694	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49959
Rifaximin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
long tibia	IMPC Knockout Mouse Phenotypes	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23199
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.96178
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15642_KD_Sf3a1_SRP043160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.49084
Hand Polydactyly	DisGeNET Gene-Disease Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_18558_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.45584
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8325
Perturb_11851_KO_Ypel3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.80499
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.02485
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881432
Joubert syndrome with orofaciodigital defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.831
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24333
NCIH2882	DepMap CRISPR Gene Dependency	1.0	2.05436
MYB	ENCODE Transcription Factor Targets	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.05848
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21113
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.088
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82297
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3363
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281836
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.992379
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97161
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55556
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51092
abnormality of the neck	HPO Gene-Disease Associations	1.0	null
9909_XRCC6_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.529312
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07321
abnormality of the larynx	HPO Gene-Disease Associations	1.0	null
Perturb_17880_KO_Hhex_SRP313523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.39325
MAML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4045
GSE67266_5_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RA-49-ZB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42469
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29432
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831377
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93143
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308251
PMC12441061-10157_2025_2675_MOESM2_ESM.docx-5-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Severe Hydrocephalus	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090387
Tolvaptan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.44
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13612
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UA-39-TN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328922
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Corpus callosum agenesis-abnormal genitalia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.91741
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.32746
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.474
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855115
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941878
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1515
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87471
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858562
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15518_KD_Nsd2_SRP158408	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.32465
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24864
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.96178
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43721
short long bone	HPO Gene-Disease Associations	1.0	null
Perturb_13768_KO_Kansl2_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.73413
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69719
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14806
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
hsa-miR-4436a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926033
GTEX-QDVJ-1426-SM-48U1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30376
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21062
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06692
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16447
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
displacement of the external urethral meatus	HPO Gene-Disease Associations	1.0	null
HA-17-MS45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246077
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
Low Set Ears	DisGeNET Gene-Disease Associations	1.0	null
9210_TPP2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.517793
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.691653
Sperm individualization complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
laryngomalacia	HPO Gene-Disease Associations	1.0	null
inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616586
ventricular septal defect	HPO Gene-Disease Associations	1.0	null
mature t-cell and nk-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.635528
widened posterior fossa	HPO Gene-Disease Associations	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974388
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276242
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08438
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98056
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0663
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05117
hsa-miR-365	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8826
lymphoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139391
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.11571
PMC10591879-NIHMS1933918-supplement-2.xlsx-Down_in_NMR_OPC_differentiation-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3188
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15484
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20276
Perturb_11910_KD_Hmga2_SRP029975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3706
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.962939
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376248
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976932
PMC9314667-Table_1.xlsx-Regulons-SOX11_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Severe growth deficiency-strabismus-extensive dermal melanocytosis-intellectual disability syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
supernumerary spleens	HPO Gene-Disease Associations	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09924
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25821
prolonged PQ interval	MGI Mouse Phenotype Associations 2023	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30827
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906379
Low-Set, Posteriorly Rotated Ears	DisGeNET Gene-Phenotype Associations	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056054
N6022	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51723
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26719
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TAF15_02_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61193
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96155
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83504
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.475974
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.748389
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08682
Perturb_13837_KO_Mov10_SRP091426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.88632
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12305
abnormality of the uterus	HPO Gene-Disease Associations	1.0	null
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.206
DF-00-BX35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279985
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902438
accessory spleen	HPO Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24345
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10908_KD_Eif3m_SRP157047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03149
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05744
nucleus	GO Cellular Component Annotations 2023	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105475
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831198
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990526
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Culler-Jones syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.056
DA-80-IY83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303437
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15322
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41215
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.32895
Skin Cutaneous Melanoma_SKCM_TCGA-IH-A3EA-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13279_KO_Ythdf1_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.93032
osteosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07312
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13263_KO_chr7_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.0458
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08873
great saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.820248
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.38317
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54434
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849865
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864535
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534647
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1737
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dermatitis herpetiformis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205585
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923327
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358948
HCC366	CCLE Cell Line Gene Expression Profiles	1.0	2.0111
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
agenesis of the diaphragm	HPO Gene-Disease Associations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6878
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50749
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08769
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1716
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27876
GTEx BloodVessel 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-19.9225
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the renal pelvis	HPO Gene-Disease Associations	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2529
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31426
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.32991
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.47762
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00224
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30511
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.43982
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03985
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A2780	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65446
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844436
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.090828
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235366
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947382
Perturb_4680_KO_Psip1_SRP153901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.8488
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43483
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99549
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874594
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40657
IF-06-KQ42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270375
CA-48-SW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259822
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31249
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59681
GSE48812_3_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05305
SP2509	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.08
cleft palate	HPO Gene-Disease Associations	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	2.61956
m90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046113
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1164
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48272
Perturb_10784_KO_Mlkl_SRP370632	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52197
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1915	CCLE Cell Line Gene Expression Profiles	1.0	1.40849
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988064
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.332
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849605
cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.402859
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22777
Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of adrenal morphology	HPO Gene-Disease Associations	1.0	null
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399515
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22707
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34402
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32657
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44683
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.865
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.816498
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9338
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02438
anaplastic large cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.846259
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11712
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
holoprosencephaly	HPO Gene-Disease Associations	1.0	null
GSE130437_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088766
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.779787
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Von Hippel-Lindau Syndrome	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0738
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982958
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052454
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344586
BD-41-DB55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204401
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49738
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4758-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MM127	DepMap CRISPR Gene Dependency	1.0	4.55992
SOX2	ChEA Transcription Factor Targets	1.0	null
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42817
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.9281
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17973
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12046
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13797
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36494
SNU761	DepMap CRISPR Gene Dependency	1.0	2.07657
SUPT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73635
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38125
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38929
ISO-1	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954006
Median Cleft Lip	DisGeNET Gene-Disease Associations	1.0	null
TR-14035	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20939
LS411N	DepMap CRISPR Gene Dependency	1.0	5.00838
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827425
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6706
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53537
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37342
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3118
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.6091
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12209513-JDI-16-1263-s001.pdf-7-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18212
teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077374
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9855
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.999094
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990575
JD-70-IC84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243448
IE-49-AI35_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396537
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.368153
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10663
GSE112762,GSE112767_1_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76374
GSE218060_7_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.84704
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53731
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
abnormality of the abdominal wall	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920314
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40707
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1228
hsa-miR-1287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09915
Perturb_11035_KO_Spock2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60825
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15035
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.85547
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75138
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.73609
Congenital Omphalocele	DisGeNET Gene-Disease Associations	1.0	null
Multiple epiphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51465
Perturb_8694_KO_METTL1_SRP314965	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_10909_KD_Eif3m_SRP157047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87329
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27382
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23277
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35617
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517284
Atrioventricular Septal Defect	DisGeNET Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31764
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16208
NA-16-OJ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295096
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11485
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21931
Agranular insular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35463
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84736
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045751
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16501
Asphyxiating thoracic dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.73
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31874
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
bone cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069939
Perturb_12524_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340302
abnormality of the corpus callosum	HPO Gene-Disease Associations	1.0	null
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27096
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26208
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990723
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13923
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865638
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94257
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39006
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30724
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33169
hsa-miR-1197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_13448_OE|KD_PAX2|PTEN_SRP279768	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.1806
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39317
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Acrocallosal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.263
E2F4	ENCODE Transcription Factor Targets	1.0	null
autoimmune hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325552
Autosomal dominant intellectual developmental disorder 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.604656
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13779
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056775
Perturb_13316_KD_Foxc1_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.36909
abnormality of the trachea	HPO Gene-Disease Associations	1.0	null
BC-63-DM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372898
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17107
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383983
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35167
dilated fourth ventricle	HPO Gene-Disease Associations	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489816
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the lymphatic system	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16308
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02308
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98889
PMC12484339-467_2025_6878_MOESM5_ESM.docx-0-GLIS3_GLIS3	Rummagene Transcription Factor Associations 2026	1.0	null
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411623
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899383
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69623
Vorinostat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.72
limb undergrowth	HPO Gene-Disease Associations	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990062
CAL120	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.28171
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.40502
CAPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.35848
b-lymphoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160877
Perturb_5253_KD_Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CB-32-EI69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214768
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05286
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03205
molecular_function	GO Molecular Function Annotations 2015	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.881882
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43653
PMC3470785-NIHMS377161-supplement-3.pdf-421-HOXB1_HOXB1	Rummagene Transcription Factor Associations 2026	1.0	null
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068014
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01338
AB-43-XJ34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.654384
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49841
abnormal morphology of bones of the lower limbs	HPO Gene-Disease Associations	1.0	null
endocrine-cerebro-osteodysplasia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12532
mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04885
17533364-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134938
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71644
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993071
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.43247
REST	ENCODE Transcription Factor Targets	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775664
Lymphoid cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_57_KD_Suv39h2_SRP185804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79606
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67275
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874595
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hernia of the abdominal wall	HPO Gene-Disease Associations	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863954
Gliclazide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289407
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330973
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.913
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91443
Sarcoma_SARC_TCGA-PC-A5DP-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11122_KD_Eif3m_SRP162708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87329
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
639V	CCLE Cell Line Gene Expression Profiles	1.0	1.49189
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3441
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028213
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27279
inner CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950342
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15469
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6205
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894576
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	3.33646
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05595
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070406
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5768
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3634
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320449
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8243
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C2BBE1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75117
Perturb_3742_KO_Cd274_SRP215305	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.22397
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.894
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933652
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920336
premature birth	HPO Gene-Disease Associations	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70408
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846272
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23595
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.974911
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12808
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20883
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.25
EVSAT	DepMap CRISPR Gene Dependency	1.0	3.67723
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.023894
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50982
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.18993
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19312
LCLC103H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9901
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NSC43673	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11578
Periciliary membrane compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.986
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2888
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215206
Agenesis of the corpus callosum with peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34648
R-848	DeepCoverMOA Drug Mechanisms of Action	1.0	0.46
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.60733
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965736
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76876
extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.382884
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1815
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2639
b-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149712
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
PL18	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
Joubert syndrome 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
hand polydactyly	HPO Gene-Disease Associations	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11364504-41388_2024_3115_MOESM2_ESM.pdf-28-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_460_KD_CCR3_SRP220486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PX-12	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.85
Electrocardiogram morphology (amplitude at temporal datapoints)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07448
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923327
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
PDK1-In	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0016
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325385
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40288
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01039
ZXDC_KD_GDS5070_504_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IE-80-DC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559832
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4429
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5141_KO_Rn7sk_ERP002405	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01649
husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12394
HCC1195	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72126
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14142
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_14564_KO_Ubap2l_SRP296872	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.69934
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60901
Chromosome Deletion	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bifid Uterus	DisGeNET Gene-Phenotype Associations	1.0	null
non-motile cilium	GO Cellular Component Annotations 2023	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Bifid Uvula	DisGeNET Gene-Disease Associations	1.0	null
Pituitary hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-3688-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2139
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041852
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46397
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52947
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57288
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.617
Hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Perturb_4446_KD_Fbl_DRP007972	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67256
abnormal location of ears	HPO Gene-Disease Associations	1.0	null
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928885
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68043
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.92104
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.827865
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31716
Polydactyly	DisGeNET Gene-Disease Associations	1.0	null
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403172
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.895479
WM88	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2146
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51592
TCF7	ChEA Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858583
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327004
SKNDZ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7157
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1518
HCC44	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37113
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997746
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4039
Procentriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.62
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26193
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24346
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963624
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721496
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31677
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46042
hypersensitivity reaction type iv disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06742
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400705
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29176
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuromuscular junction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.13871
HT1197	DepMap CRISPR Gene Dependency	1.0	2.31328
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30854
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81874
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18288
PMC9616830-42003_2022_4093_MOESM3_ESM.csv--Zhang2019_FOXN4_cell_FOXN4	Rummagene Transcription Factor Associations 2026	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06336
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836478
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03071
organelle assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10826
smoothmuscle_8c	HPA Tissue Sample Gene Expression Profiles	1.0	0.91786
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45166
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WM3772F	DepMap CRISPR Gene Dependency	1.0	7.34605
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54197
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41811
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13667
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882782
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4R8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCI-34051	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5311
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18233
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13325_KD_Klf8_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13337
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565588
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09861
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08377
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518861
BE-38-UW72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295042
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347293
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.294007
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46858
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479702
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7799
SNU601	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15634
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58237
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.57603
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7736
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10279_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73238
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.08534
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	1.0	2.15541
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorzolamide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
GSE153757,GSE153758_0_v_2_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.69597
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.905
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4194
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	1.64319
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06957
Perturb_13315_KD_Fosl2_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.18385
abnormality of cardiac ventricle	HPO Gene-Disease Associations	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27414
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05822
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_5_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968419
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	58.9173
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.444878
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67935
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
addison's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.464283
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339617
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77818
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1624
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09327
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.22108
abnormality of the tibia	HPO Gene-Disease Associations	1.0	null
prenatal lethality prior to heart atrial septation	IMPC Knockout Mouse Phenotypes	1.0	null
cilium organization	GO Biological Process Annotations 2025	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22634
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60347
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-71-CI37_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207102
CE-18-CG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445171
Ciliary inversin compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56634
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442982
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08817
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17596
aplasia/hypoplasia affecting the eye	HPO Gene-Disease Associations	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
carried	GeneRIF Biological Term Annotations	1.0	null
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69346
Perturb_13265_KO_chr3_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077363
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916967
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7532
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438739
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-13-ZM96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208472
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.48838
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5325
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43722
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49383
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_2376_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9412_KD_Pcbp1/Platr18_SRP251371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.86619
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.759824
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098917
Perturb_13047_KO_YAP1/WWTR1_SRP212218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.20239
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685556
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77735
NB1	DepMap CRISPR Gene Dependency	1.0	3.27025
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26821
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19222
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00896
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01961
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893189
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50496
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RDES	CCLE Cell Line Gene Expression Profiles	1.0	1.44234
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987301
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04828
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882782
Perturb_28_OE_Smad1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25193
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
abnormality of female internal genitalia	HPO Gene-Disease Associations	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.282
FOXM1-26456572-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.22884
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885808
varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.592895
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05091
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08777
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.909
Perturb_14649_KD_Paf1_SRP297013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8689
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.699165
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16665
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352993
abnormal internal genitalia	HPO Gene-Disease Associations	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55468
abnormality of the calf	HPO Gene-Disease Associations	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10404
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08774
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	3.13022
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12217
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hydrolethalus syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.482
chediak-higashi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.381852
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22759
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48568
Selisistat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03477
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505495
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13686
Perturb_13262_KO_chr9_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.82184
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211667
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170544
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17058
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67969
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25066
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12802
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836677
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28858
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20702
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565631
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07547
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20828
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.946274
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08421
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962809
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35971
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.588431
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079214
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
abnormality of the skull base	HPO Gene-Disease Associations	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the spleen	HPO Gene-Disease Associations	1.0	null
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05988
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168148
proximal tibial hypopolasia	HPO Gene-Disease Associations	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.49305
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446038
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07448
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230191
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.482921
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.882694
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69281
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337449
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormal Form Of The Vertebral Bodies	DisGeNET Gene-Phenotype Associations	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236565
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07448
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15198
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8955
histiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2559
Perturb_13233_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01456
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872692
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16710_KO_Phpt1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.41352
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7426
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89586
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4710_KO_Sox9_ERP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9723
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837569
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13266_KO_chr3_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53039
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94497
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.35687
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59737
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49332
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.4591
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841769
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850346
Abnormality Of The Fallopian Tube	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_4810_KO_Atp2b4_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.88274
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar malformation	HPO Gene-Disease Associations	1.0	null
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26797
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00235
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02266
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070434
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13582
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.541332
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2555
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60902
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62891
Perturb_13310_KD_Cnbp_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58104
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26658
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.202
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93122
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.676172
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of toe	HPO Gene-Disease Associations	1.0	null
Perturb_7966_OE|KO_MPL_SRP287959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.5114
Perturb_4529_KD_Chaf1b_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.56982
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02266
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.76892
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.313915
alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.378143
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0709
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75995
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291771
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.91755
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80051
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_16604_KO_Phb_SRP229743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.22935
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15469
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Biparietal Narrowing	DisGeNET Gene-Phenotype Associations	1.0	null
Polymicrogyria	DisGeNET Gene-Disease Associations	1.0	null
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835709
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872626
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02502
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16509
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polyhydramnios	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.20493
Perturb_15678_KD_Srsf6_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8564
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58538
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503533
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5985
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833404
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51969
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05176
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormality of finger	HPO Gene-Disease Associations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859569
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883866
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.138412
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29955
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916237
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10215_KO_Csnk1a1_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.8136
Hydrolethalus syndrome protein 1, C-terminal domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63412
adrenal cortical hypofunction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.460129
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05542
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.34307
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.13621
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.50347
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.921663
GSE139455_4_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982483
Ibutamoren	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21216
Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151898
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19508
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.337242
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27751
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14897
Abnormality Of The Pinna	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11177
ventral pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09861
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850469
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	5.40624
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	HPO Gene-Disease Associations	1.0	null
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
ETS1_01_244	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.62253
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29811
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40777
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.972654
Neuronal Heterotopia	DisGeNET Gene-Disease Associations	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52762
micromelia	HPO Gene-Disease Associations	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920213
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
splenic marginal zone lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
Perturb_14568_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07457
abnormality of the face	HPO Gene-Disease Associations	1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25846
Perturb_16714_KO_Selenbp1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41577
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_1822_KO_Irf5_SRP233379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.96943
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842754
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esophageal varix	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Tazarotene2	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
abnormality of the adrenal glands	HPO Gene-Disease Associations	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1784
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.86555
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6557
upper dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3099
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.943678
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9791
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.05132
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the female genitalia	HPO Gene-Disease Associations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.932496
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.870065
non-hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.799923
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907573
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84687
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09696
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10955
short-rib thoracic dysplasia 6 with or without polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11431
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.19073
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360705
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92855
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA-68-TC79_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244689
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13575
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3729_KO_Arid5a_SRP288358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64183
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394102
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2110	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5365
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01453
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842578
Perturb_1821_KO_Irf5_SRP233379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.86401
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5735
NCIH2228	CCLE Cell Line Gene Expression Profiles	1.0	1.52383
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08404
Perturb_13282_KO_Ythdf3_SRP254797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.80856
FOXM1-23109430-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.208481
AC-33-YJ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238873
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93545
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14566_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.3021
HF-79-EC41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227782
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	5.52536
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.690782
gastrocnemius	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811056
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19057
jy cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648127
GSE112762,GSE112767_2_v_0_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.56154
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835198
Entinostat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.14
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6598
abnormality of the 5th finger	HPO Gene-Disease Associations	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4582-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aplasia/hypoplasia of the corpus callosum	HPO Gene-Disease Associations	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42817
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23714
tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12305
Perturb_15850_KO_Etv5_SRP165224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78787
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53977
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8558
quadriceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229568
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00183
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70315
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16852
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00995
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069041
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9948
Perturb_18555_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.6038
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17222
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UK 356618	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36161
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07822
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058197
KC-26-JQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.773362
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21221
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02192
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03506
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25378
Perturb_13330_KD_Nfat5_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.37831
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053802
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39693
hsa-miR-3689b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15394
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67709
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271447
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222122
Hydronephrosis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_4528_KD_Chaf1a_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.89155
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3689e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16853
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2739
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5968
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72395
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64844
talipes equinovarus	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56524
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.28179
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73648
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40624
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357676
Joubert Syndrom	DisGeNET Gene-Disease Associations	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.38734
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2868
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5812-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18546
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03938
Joubert syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79228
lambert-eaton myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.548195
Perturb_10660_KD_Urod_SRP226321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074061
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5262-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JF-16-BD66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215814
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.11081
RASSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02015
hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05457
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07547
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of connective tissue	HPO Gene-Disease Associations	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02005
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.479
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985926
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55187
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136206
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
Perturb_14567_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.224196
Retrognathia	DisGeNET Gene-Disease Associations	1.0	null
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38295
hela	HPA Cell Line Gene Expression Profiles	-1.0	-1.06314
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892295
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100629_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1135
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72439
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25544
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal cortical gyration	HPO Gene-Disease Associations	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.73075
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4405
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06412
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36517
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.39247
abnormality of globe size	HPO Gene-Disease Associations	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769441
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947202
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8307
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871035
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905177
MUTZ8	DepMap CRISPR Gene Dependency	1.0	4.80428
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046054
Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal heart looping	IMPC Knockout Mouse Phenotypes	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0795
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00219
abnormality of the upper respiratory tract	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1867
Monoclonal gammopathy of undetermined significance (MGUS)_Bone Marrow_GSE5900	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.82803
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
duplication of bones involving the upper extremities	HPO Gene-Disease Associations	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.731
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9942
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14832
non-midline cleft lip	HPO Gene-Disease Associations	1.0	null
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960284
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.075752
GSE202434,GSE202438_13_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_4_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A762-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.674356
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977377
abnormal heart looping	MGI Mouse Phenotype Associations 2023	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047094
long tibia	MGI Mouse Phenotype Associations 2023	1.0	null
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104245
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
tracheal stenosis	HPO Gene-Disease Associations	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074061
hsa-miR-1303	MiRTarBase microRNA Targets	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279397
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448598
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188274
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
SW1783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.35567
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.36312
Perturb_3272_KO_AMPK_SRP389002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3913
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JZL 184	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
Tremor	DisGeNET Gene-Phenotype Associations	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21018
Perturb_5710_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital disorder of glycosylation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Tadalafil	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53978
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.848737
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.386
Perturb_9546_KO_Cdk7b_SRP257915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.34841
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28917
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9798
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PD-50-SI33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271077
MERO14	DepMap CRISPR Gene Dependency	1.0	7.92486
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Perturb_13847_KO_Mov10_SRP091426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9479
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201981
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844
abnormality of long bone morphology	HPO Gene-Disease Associations	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00478
CAY10550	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
VD-08-TC47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232096
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937131
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856772
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic growth retardation	MGI Mouse Phenotype Associations 2023	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041571
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06638
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4498179-srep11671-s1.pdf-225-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903347
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4275
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.041
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55903
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13324
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.082
abnormality of the cerebral white matter	HPO Gene-Disease Associations	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2082
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964292
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0415
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.724
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043923
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37337
cisplatin_homo sapiens_gpl6480_gse33482	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
cilium assembly	GO Biological Process Annotations 2025	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the thumb	HPO Gene-Disease Associations	1.0	null
Cerebral Palsy	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Palonosetron	DeepCoverMOA Drug Mechanisms of Action	1.0	0.3
Perturb_1848_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.28801
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.29413
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.96451
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02148
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864074
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hypogonadotropic hypogonadism 12 with or without anosmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13546
BMS309403	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_1873_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.879
Ellis-Van Creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14153
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6409
9505BIK	DepMap CRISPR Gene Dependency	1.0	3.11364
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06245
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00626
Joubert syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
SNCA_KO_GDS4153_530_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427659
Perturb_8398_KD_Safb_SRP180874	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.07364
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UD-07-US73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357926
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7441_RPL17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.564846
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861016
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26488
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91894
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049795
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.357
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09667
GSE246195,GSE246305_1_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3549
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043792
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1509
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254332
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.15155
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15139
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.331
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.75599
marginal zone b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248905
Perturb_14678_KO_Prmt1_SRP153406	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26599
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB-55-KL42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230787
Congenital Atresia Of Trachea	DisGeNET Gene-Disease Associations	1.0	null
dilatation of the renal pelvis	HPO Gene-Disease Associations	1.0	null
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47778
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2161
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98944
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.09226
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153385
aplasia involving bones of the extremities	HPO Gene-Disease Associations	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14146
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11949941-DataSheet1.pdf-50-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15806
hsa-miR-1276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.13448
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30027
median cleft lip	HPO Gene-Disease Associations	1.0	null
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.776
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87108
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07141
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05134
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67446
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178588
H3K36me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QZ-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Cranioectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Adenocarcinoma of lung_Lung Tissue_GSE11969	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.76088
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5409
Holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.838
ZB-16-BR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295114
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510426
sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167915
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66573
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979298
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.907766
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1343
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122954
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086499
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.36832
Perturb_212_KD_AU021063_SRP324142	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.0182
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cases	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892687
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.769804
Perturb_13728_KD_KRAS_SRP116072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1096
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cetirizine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14821
aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.830291
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11976
abnormality of the phalanges of the hallux	HPO Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2947
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4155
binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931271
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371481
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88186
Ptosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.05816
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404427
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49813
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955907
Oculovestibuloauditory Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.0045
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28626
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.19223
Perturb_16832_OE_Myc_SRP250081	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.88341
microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAX	ENCODE Transcription Factor Targets	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24464
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69125
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22968
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11905
microphthalmos	HPO Gene-Disease Associations	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.846021
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14056
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95507
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52416
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14485
deeply set eye	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TE4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36686
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12660832-41439_2025_333_MOESM1_ESM.docx-0-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48167
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42949
Perturb_15035_KD_Ctcflos_SRP311201	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21283
Perturb_3100_KO_Mid1ip1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96788
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02382
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.769804
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7461
HIPK2_knockdown_106_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.68607
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.11518
CAKI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85138
Perturb_9562_KO_Ogt_SRP110508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.528
EFO27	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.40262
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.877745
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29361
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.05816
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01631
BF-10-IO69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200391
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.584
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67119
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826498
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46175
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35051
non-motile cilium	GO Cellular Component Annotations 2025	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	1.0	0.99001
A 922500	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
DA-58-LZ09_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410078
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2722
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
despite	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19212
GA-04-JM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352178
Perturb_14215_KO_Psen2_SRP254653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51342
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872982
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-11.2154
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514425
mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04711
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078126
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.42535
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49848
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03469
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949381
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02885
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906011
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052386
all	GeneRIF Biological Term Annotations	1.0	null
abnormality of the ventricular septum	HPO Gene-Disease Associations	1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9813
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10205
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863732
GSE161295_2_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11527
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17_OE_Carhsp1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.63495
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65686
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25557
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.33092
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05987
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836918
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07444
Perturb_4940_KO_Cbfa2t2_SRP061948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.31759
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244512
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942502
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44402
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
18387200-Genes	GeneSigDB Published Gene Signatures	1.0	null
NP118809	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00678
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.778
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938348
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37415
SCC9	DepMap CRISPR Gene Dependency	1.0	2.40196
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1658
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40932
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0675
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24284
NCIH526	CCLE Cell Line Gene CNV Profiles	1.0	2.32368
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5344
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047819
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27792
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05044
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01353
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1632
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPE1SS6	DepMap CRISPR Gene Dependency	1.0	2.03623
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	2.27185
Ataxia	DisGeNET Gene-Phenotype Associations	1.0	null
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311507
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042272
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48638
LUBIPROSTONE	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
FOXN4+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902143
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966036
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17069
oral cleft	HPO Gene-Disease Associations	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11203
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450581
ZXDC1_KD_GSE45417_686_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46023
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71247
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655744
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3567
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2621
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29547
Perturb_1866_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.54148
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988856
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17592
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856815
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nephronophthisis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935181
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	3.32394
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31259
COV434	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.1739
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preaxial hand polydactyly	HPO Gene-Disease Associations	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81147
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60429
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26459
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1764
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
FA-65-UA27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257214
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03752
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10158
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874343
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the cerebral ventricles	HPO Gene-Disease Associations	1.0	null
Perturb_8674_KD_CircINSR_SRP365091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.68649
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06522
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hypoxia_Astrocyte_GSE4483	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.96484
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29759
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3689f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_1271_KO_Adar_SRP132963	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.60481
centrosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
km-h2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17181
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FED48h_vs_D2FAST48h_968_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042544
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_18556_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06877
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93545
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28445
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18638
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16123
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18631
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.13963
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_5150_KO_Thap11_ERP126456	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3325
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_11813_KO_Mid2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.94498
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04466
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865413
BL7442 (ZNF639)	NURSA Protein Complexes	1.0	null
Panhypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14769
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10101
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16732_KO_3110043O21Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.84503
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1221
severe hydrocephalus	HPO Gene-Disease Associations	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71342
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61392
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182422
abnormality of the cerebral subcortex	HPO Gene-Disease Associations	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34678
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64194
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13704
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54104
KE-41-JG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226889
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE203158_5_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460725
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11893
spine apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.307377
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973042
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.15496
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55999
Ring centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.956
GSE133286,GSE133299_1_v_0_tepoxalin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9484_KO_Tcf7/Lef1_SRP251706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.32864
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2139
Oculomotor Apraxia	DisGeNET Gene-Disease Associations	1.0	null
complete atrioventricular canal defect	HPO Gene-Disease Associations	1.0	null
Aplasia/Hypoplasia Of The Corpus Callosum	DisGeNET Gene-Phenotype Associations	1.0	null
Sarcoma_SARC_TCGA-DX-A3U7-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A181-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC18A3_KD_GDS4325_618_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089192
ATPAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48247
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Atosiban	DeepCoverMOA Drug Mechanisms of Action	1.0	0.54
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885231
Perturb_7075_KO_OGT_SRP252759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79907
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.826523
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9738
Subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80285
phenotype	GeneRIF Biological Term Annotations	1.0	null
FOXM1-23109430-U2OS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16414
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059106
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIAPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01503
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Abnormality Of The Hypothalamus-Pituitary Axis	DisGeNET Gene-Disease Associations	1.0	null
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-10.59
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21686
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922251
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044495
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08365
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45234
PA1	DepMap CRISPR Gene Dependency	1.0	2.28219
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91334
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045083
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NIHOVCAR3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.37882
Perturb_16696_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.82911
hemocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419242
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22677
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.09297
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3144
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06874
diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.31618
OB-06-WW76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374585
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309191
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843823
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70613
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72606
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5
hsa-miR-215-5p	MiRTarBase microRNA Targets	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55613
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44644
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00568
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851474
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.641496
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082951
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41377
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68501
6024_PABPC1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.604718
DA-07-LL18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379344
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05824
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49866
PMC8160578-JCB_202009147_TableS4.xlsx-FOXM1_targets-Genes_n_696_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840077
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857895
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486276
Perturb_11839_KO_Slc7a13_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54834
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14022
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04849
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18242
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16727_KO_Mbd2_SRP326773	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.87973
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53101
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54024
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13927
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917141
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20648
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.359752
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07245
bone cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069272
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2727
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752073
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40293
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.039646
vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.834899
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359985
Perturb_1841_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.60815
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03191
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875658
GTEx Breast 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.81997
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87933
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410803
Perturb_4366_KO_Qki_SRP153187	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53668
PMC5997284-NIHMS973253-supplement-4.xlsx-Sheet1-MMB_FOXM1_Targets_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05499
coronary stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221108
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9666
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999337
GSE112760,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hemolymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.711729
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17872
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.89848
hydrocephalus	HPO Gene-Disease Associations	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69726
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.612
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8939
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.828616
EW7	DepMap CRISPR Gene Dependency	1.0	3.44603
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35264
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987584
NRF1	Pathway Commons Protein-Protein Interactions	1.0	null
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4301
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860875
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19534
Perturb_166_KD_Mir21_SRP361611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.43624
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	2.03288
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243295
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
Acute Myeloid Leukemia_LAML_TCGA-AB-2862-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00974
MHHNB11	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47715
burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102076
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30123
Cloprostenol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.70097
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870384
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.58762
Retinal Vein Occlusion	DisGeNET Gene-Disease Associations	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4167
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09266
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24056
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903855
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2871
polyhydramnios	HPO Gene-Disease Associations	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740632
hsa-miR-4677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43446
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19321
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16744
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40581
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.1649
Cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847543
Perturb_14946_KD_Nmnat1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.57107
osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415434
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66529
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966391
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13282
Rislenemdaz	DeepCoverMOA Drug Mechanisms of Action	1.0	0.2
Ezatiostat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.51488
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921912
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40591
IRF1	ENCODE Transcription Factor Targets	1.0	null
osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160387
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343646
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1593
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31488
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57616
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259825
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29265
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31522
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8535
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7646
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929007
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343794
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129465_3_v_2_phf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
Absence Of Septum Pellucidum	DisGeNET Gene-Disease Associations	1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-MYBL2_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71246
adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140292
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00556
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07321
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957378
JHESOAD1	DepMap CRISPR Gene Dependency	1.0	2.29866
diffuse large b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.879424
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	0.887329
aplasia/hypoplasia of the diaphragm	HPO Gene-Disease Associations	1.0	null
centrosome	GO Cellular Component Annotations 2015	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.1172
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.71551
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.44483
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99277
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FB-29-KC76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206996
heterotopia	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55057
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469599
WM983B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57113
PMC4387713-supp_gad.255984.114_Table_S3.xlsx-S3A-Down_Dpy30_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7431
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23469
PMC6459557-pbio.3000201.s012.xlsx-Sheet1-FOXD1_FOXD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824221
SW948	DepMap CRISPR Gene Dependency	1.0	2.155
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.84337
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862671
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23204
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0291
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07803
venous insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324823
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2455
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22643
Highly Arched Eyebrow	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_12127_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89172
Desvenlafaxine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
hESC Derived CD184+ Endoderm Cultured Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.04004
EA-17-BY69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208979
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01272
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49186
GSE144745_0_v_1_mettl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.05816
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.083848
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89363
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954006
NCIH854	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48814
TAL1	ENCODE Transcription Factor Targets	1.0	null
FB-39-CW59_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267325
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the cerebral cortex	HPO Gene-Disease Associations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.492963
abnormality of the hallux	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01915
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH446	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50132
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03894
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06793
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834447
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5056
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.567
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68417
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11833_KO_Rhbdf2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73739
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927319
absent septum pellucidum	HPO Gene-Disease Associations	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064263
CE-37-XI06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254643
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68823
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_significantly_downregulated_739_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11647
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0847
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5239
abnormality of the head	HPO Gene-Disease Associations	1.0	null
bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.109899
RMSYM	DepMap CRISPR Gene Dependency	1.0	4.2185
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1049
42MGBA	DepMap CRISPR Gene Dependency	1.0	2.30868
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01706
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14018
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of the cerebrospinal fluid	HPO Gene-Disease Associations	1.0	null
MLS0315771	DeepCoverMOA Drug Mechanisms of Action	1.0	0.64
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.883885
abnormality of the vagina	HPO Gene-Disease Associations	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6859
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.26794
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376836
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63311
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866482
CA-42-YI34_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201178
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15442
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256456
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36782
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10373
superficial stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02452
Abnormality Of The Sense Of Smell	DisGeNET Gene-Phenotype Associations	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61186
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19255
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.72431
abnormality of the diaphragm	HPO Gene-Disease Associations	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917939
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.363
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201443
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.1153
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826334
depression	GWASdb SNP-Phenotype Associations	1.0	0.358704
duplication of phalanx of hand	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04172
NCIH647	DepMap CRISPR Gene Dependency	1.0	3.54704
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.769804
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.74629
Sunken Eyes	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_17442_OE|Mut_Tal1|Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.34214
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.349988
congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.226952
variation	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
Hydrolethalus Syndrome 1	CTD Gene-Disease Associations	1.0	2.88009
microtubule organizing center	GO Cellular Component Annotations 2015	1.0	null
OVSAHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81515
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07259
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00154
Gait Disturbance, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13418
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.05816
Hyperplasia	CTD Gene-Disease Associations	1.0	1.55451
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98618
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55528
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17819
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9239
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4638
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00854
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8278
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
prenatal lethality prior to heart atrial septation	MGI Mouse Phenotype Associations 2023	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43782
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.57625
Micromelia	DisGeNET Gene-Disease Associations	1.0	null
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300924
upper limb undergrowth	HPO Gene-Disease Associations	1.0	null
Sperm connecting piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
HT115	DepMap CRISPR Gene Dependency	1.0	2.73686
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17197
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0024
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.53944
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1452
Brain Lower Grade Glioma_LGG_TCGA-DB-A64L-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942609
SNU761	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92658
abnormality of digit	HPO Gene-Disease Associations	1.0	null
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7343
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966391
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BN-01B-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18033
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361167
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906296
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0555
Perturb_16850_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52881
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462451
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
abnormality of phalanx of finger	HPO Gene-Disease Associations	1.0	null
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.2645
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21946
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075853
Anamorelin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.48
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68366
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56747
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.19802
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GC-46-AX49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332171
Perturb_13264_KO_chr7_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.9318
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42352
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00222
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05168
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
culture condition:-grown cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.981084
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95374
Investment cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.104
Perturb_13267_KO_chr2_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_11816_KO_Nhlh2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.83106
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29098
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322158
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
short tibia	HPO Gene-Disease Associations	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871503
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21629
Perturb_16922_OE_miR26a_SRP216065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.51519
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16547
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24365
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65141
Palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333378
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14277
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.8141
phlebitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231795
organelle assembly	GO Biological Process Annotations 2025	1.0	null
7478_RPL7L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.760401
Duplication Of Phalanx Of Hallux	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24811
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.788964
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.068
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18944
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870796
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46164
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEL285	DepMap CRISPR Gene Dependency	1.0	2.57376
preaxial polydactyly	HPO Gene-Disease Associations	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26752
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
postaxial polydactyly	HPO Gene-Disease Associations	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
atrioventricular canal defect	HPO Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73787
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
HC-18-NB46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214321
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834277
Congenital Coloboma Of Iris	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01678
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.887
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06877
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14917
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967249
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32106
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32143
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11576
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.90332
mantle cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.513802
omphalocele	HPO Gene-Disease Associations	1.0	null
broad neck	HPO Gene-Disease Associations	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898979
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983757
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752138
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13704
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.57075
PMC12125067-10157_2025_2629_MOESM3_ESM.docx-8-HOXA13_HOXA13	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.73177
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hodgkin's lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.71453
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12227
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.870651
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9119
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42535
AC-71-YF45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24749
4908_MCOLN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.918819
Perturb_7091_KO_Ctnnb1_SRP270859	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51321
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18604
hsa-miR-4758-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.5405
b-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.933727
organelle part	GO Cellular Component Annotations 2015	1.0	null
tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05209
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06093
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22714
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331319
PMC7160301-Data_Sheet_1.xlsx-Sup_Table_9-NRF1_interaction_partners_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25154
histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.420036
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987099
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13788_KO_Mcph1_SRP233207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.47172
GSE168750_0_v_1_slc7a5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996181
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-9-TBX3_TBX3	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32501
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97478
Perturb_17823_KO_Kansl2_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75478
Perturb_12674_KD_Sox10_SRP191908	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.28971
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870755
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36582
Perturb_13261_KO_chr9_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.90028
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62073
3537_GRINA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.704213
T47D	CCLE Cell Line Gene CNV Profiles	1.0	2.12159
rheumatic fever	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.235964
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31843
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03368
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02266
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.383708
FE-06-GR60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23083
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.989396
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93755
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	0.940804
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073786
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.33448
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841592
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061194
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.957
Perturb_17585_KO_Nubpl_ERP016523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.6498
midline defect of the nose	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09852
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334401
Osteoarthritis_Chondrocyte_GSE16464	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.52544
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10543
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12151
polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210203
RPE1SS48	DepMap CRISPR Gene Dependency	1.0	4.52422
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Fetal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96367
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Stillbirth	DisGeNET Gene-Phenotype Associations	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07321
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29423
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55711
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60746
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.07804
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42994
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.101343
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205205
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3474
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5941
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84434
CE-15-YU05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208471
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53143
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46459
Feeding Difficulties In Infancy	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76144
Abnormal Cortical Gyration	DisGeNET Gene-Phenotype Associations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028195
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
mature b-cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.718846
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE226249_2_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05049
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.6703
intracranial cystic lesion	HPO Gene-Disease Associations	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174361
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sitagliptin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.56
Congenital Absence Of Diaphragm	DisGeNET Gene-Disease Associations	1.0	null
Meckel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11969
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85403
CHP126	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28768
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769855
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86563
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24833
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64346
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.559
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54028
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77727
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08193
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81324
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8483
Lung squamous cell carcinoma_LUSC_TCGA-66-2755-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87933
femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14653
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2377_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.6383
PMC7021759-41467_2020_14682_MOESM8_ESM.xlsx-Upregulated_Genes-Table_S5_Upregulated_genes_in_MYCN_amplified_neuroblastoma_relative_to_non-amplified_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914169
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
autoimmune disease of cardiovascular system	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170544
Perturb_10365_KD_Setd2_SRP184682	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.41796
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843601
laryngeal hypoplasia	HPO Gene-Disease Associations	1.0	null
PMC11522069-439_2024_2703_MOESM2_ESM.xlsx-Table_S3-HsCHD_AR_N_115_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922135
abnormality of the posterior cranial fossa	HPO Gene-Disease Associations	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	2.08612
bifid nose	HPO Gene-Disease Associations	1.0	null
adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259591
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35826
lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612401
FA-92-JL46_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356009
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24659
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.36443
D502MG	DepMap CRISPR Gene Dependency	1.0	5.91287
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07291
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27682
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01781
Microphthalmos	DisGeNET Gene-Disease Associations	1.0	null
Edwards syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
ventriculomegaly	HPO Gene-Disease Associations	1.0	null
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47421
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10535
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
SARS-CoV MA15_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46178
Laryngeal Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21211
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.989
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.999344
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0535
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932342
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13233
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.835
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2289
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98046
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01789
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19377
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.824
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954006
Long Face	DisGeNET Gene-Phenotype Associations	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	2.07807
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22624
thalamus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850346
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376308
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879391
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal embryo size	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_8403_KD_Safb_SRP234723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.07364
Pallister-Hall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23745
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7798
Perturb_7549_Mut_UPF1_SRP298492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76174
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.890091
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11203
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03562
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.542764
GSE188458_2_v_3_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09005
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53914
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24983
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20947
AE-04-SN76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235064
adductor longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.916069
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.869373
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579592
autoimmune disease of blood	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.125329
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866413
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07463
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hydrolethalus syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907761
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914032
Perturb_4826_KD_Nfya_SRP149362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.95795
intermediate stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48047
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.096074
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
stillbirth	HPO Gene-Disease Associations	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55544
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20959
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30701
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311719
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.25096
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93545
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36274
PB-40-YB26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207833
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930521
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5667
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23916
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	2.30777
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886582
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05555
QF-00-NO42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282834
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
HA-32-YH61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20944
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02044
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288944
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.440162
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243799
BECKER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78288
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.833558
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09358
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.68146
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01589
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Unilateral Cleft Lip	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5027
Perturb_4276_KO_Smad2/Smad3_SRP132215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.1046
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325508
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37593
dental enamel hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.257005
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77661
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77917
WB-54-WD35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231341
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Ciliopathies	DisGeNET Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13225
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-40-KQ08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223184
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15442
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03782
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26996
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01249
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09862
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2466
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
granulomatous angiitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.978426
Perturb_4188_KO_Rest_SRP234983	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.91178
Perturb_7770_KO_SatIII_DRP005513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.1988
Perturb_13231_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.57217
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07994
stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237216
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353148
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.84527
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48879
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308889
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37624
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06933
BE-89-DG86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222685
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00568
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994755
Thalamus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40581
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34296
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94462
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25417
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37574
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13639
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886394
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21839
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23058
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082137
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40083
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313769
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55039
Perturb_6294_KO_KRT17_SRP314436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42095
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79811
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tracheal Stenosis	DisGeNET Gene-Disease Associations	1.0	null
Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intrauterine growth retardation	HPO Gene-Disease Associations	1.0	null
hydronephrosis	HPO Gene-Disease Associations	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07141
low-set ears	HPO Gene-Disease Associations	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321868
Episodic Tachypnea	DisGeNET Gene-Phenotype Associations	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08984
BC-00-YH62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381543
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4698
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.823968
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83753
Situs Inversus Totalis	DisGeNET Gene-Disease Associations	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.616156
ONS76	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20139