association	dataset	threshold value	standardized value
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11876
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5284
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20545
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7651
BRD-K64767126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03426
BRD-K30264389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00299
BRD-K07781799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05333
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
bromopride-3617	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.69239
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16766
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.09908
markers	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60136
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	2.0398
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8562
SK-GT-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
very	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
receptor ligand activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.297
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7755
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.116
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30828
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28069
BRD-K93486666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79709
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5566-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0925
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clozapine-6188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33331
BRD-K03381861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25393
BRD-K56595246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62192
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1379
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13668
hsa-miR-4666-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SQ1	CCLE Cell Line Gene Expression Profiles	1.0	2.1339
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17482709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6578
natural killer cell activation	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JT-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6934
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46864
BRD-K72359187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30296
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3102
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
tolmetin-3347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.919061
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41051
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38861
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.950925
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3555
CRCGN017_MCF10A.WT.HP_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2531
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8397
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0921
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25925
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10744
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049821
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.932311
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G32072NY	GlyGen Glycosylated Proteins	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K48143921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11841
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JAK-STAT signaling pathway	KEGG Pathways 2026	1.0	null
BRD-K62807053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20899
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96485
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33127
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4849-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.99555
biological adhesion	GO Biological Process Annotations 2015	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of mhc class i biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4173
type I interferon-mediated signaling pathway	GO Biological Process Annotations 2023	1.0	null
BRD-K95574976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6575
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2218
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.98165
ACHN	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
PMC3470785-NIHMS377161-supplement-14.pdf-100-ZFHX2_ZFHX2	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89759
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908198
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7254-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agammaglobulinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5235
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87839
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.86581
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1656
Ulcerative stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
BRD-K76900919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04173
positive regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Adult stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7546-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.24267
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Autoimmune polyendocrine syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
positive regulation of peptidyl-serine phosphorylation	GO Biological Process Annotations 2023	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23913
regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-A20242387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75926
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66344
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70899
BRD-K77032979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80411
Pericardial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1193
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97117
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
lymphocyte activation involved in immune response	GO Biological Process Annotations 2025	1.0	null
RAD51D	MSigDB Cancer Gene Co-expression Modules	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02436
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFNAR1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	1.60268
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
interferons	GeneRIF Biological Term Annotations	1.0	null
Dengue Hemorrhagic Fever	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54527
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22015
leukocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Gingival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2731	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33824
immune effector process	GO Biological Process Annotations 2015	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77079
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.71593
positive regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K66841501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09683
ibrs2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_16_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1399
NOMO-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.59456
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23461342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57757
BRD-K56950366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44766
response to stress	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51012353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12407
Subacute lymphocytic thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55183
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_Control-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46089
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S-117	GDSC Cell Line Gene Expression Profiles	1.0	1.7209
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8571
BRD-K50976856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11975
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955837
heliotrine-4739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81082552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33394
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
early	GeneRIF Biological Term Annotations	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2309
PK59	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02831
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69081
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.60275
BRD-K77401804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6076
BRD-K38417094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88267
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
B cell differentiation	GO Biological Process Annotations 2023	1.0	null
BRD-K02839126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0735
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21149
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.772
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02608
TP53_DEPLETION_GDS4070_451_human_MDA-MB-231 breast cancer cells (depleted of MUTANT-p53)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8576
brain	GTEx Tissue Gene Expression Profiles	1.0	2.17883
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ifnomega	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11517
Pancreatic adenocarcinoma_PAAD_TCGA-YB-A89D-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19710723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22268
polymorphism	GeneRIF Biological Term Annotations	1.0	null
cytokine activity	GO Molecular Function Annotations 2015	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58596567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69947
Plant scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
BRD-K73497584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28403
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	2.36402
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58729
reveal	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67567
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33971
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65352
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068045
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89258
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069121
PMC7605689__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Pauciarticular juvenile arthritis_Peripheral blood mononuclear cell_GSE1402	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.86269
BRD-K02783902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67886
lymphocyte activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
Interferon mediated signaling	WikiPathways Pathways 2024	1.0	null
BRD-K47673408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00294
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE231720,GSE231724_3_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06424
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.27172
BRD-K33102216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12955
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20312
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9666
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81728
Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0391
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04423
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CE-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25316
D-247MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
NCI-H2126	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K20157822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06722
lymphocyte aggregation	GO Biological Process Annotations 2015	1.0	null
BRD-K57830670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32754
cell differentiation	GO Biological Process Annotations 2015	1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
BHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9327
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02812
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23073
BRD-K80467627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00474
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3273
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	12.2614
Sarcoma_SARC_TCGA-DX-A8BX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
response to stimulus	GO Biological Process Annotations 2015	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06772291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09648
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22449045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44862
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
BRD-K84478344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77305
BRD-K59667434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91491
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.81205
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.5736
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5803
single-organism process	GO Biological Process Annotations 2015	1.0	null
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.71589
GB-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Brain Lower Grade Glioma_LGG_TCGA-DB-5280-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08433493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38801
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21972
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04958
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.44213
BRD-K15358569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18205
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3014
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.438282
RXF393	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76828
BRD-K30214140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32616
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77344
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854337
infection	GAD High Level Gene-Disease Associations	1.0	0.295739
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22486
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3383
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58315
Oral rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
BRD-K70751829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12435
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976374
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07939
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7437
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19602
interferon	GeneRIF Biological Term Annotations	1.0	null
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00551
BRD-K91628074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41238
Thymic medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75691
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1107
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87729
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59130962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49307
debrisoquine-3207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	3.09082
G74724QE	GlyGen Glycosylated Proteins	1.0	null
Severe COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Stiff-Person syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1558
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K02833343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54203
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1382
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.479
other	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12224
BRD-K47271260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51551
BRD-K64449549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25641
lymphocyte activation involved in immune response	GO Biological Process Annotations 2023	1.0	null
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3315
lymphocyte differentiation	GO Biological Process Annotations 2015	1.0	null
BRD-A63503250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10067
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48233
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K83547183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44997
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82145
cSARS Bat SRBD_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.86766
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968425
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5091
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49347
PANC0327	CCLE Cell Line Gene Expression Profiles	1.0	1.49775
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
Melanoma and neural system tumor syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Interferon regulatory factor 7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
BRD-K85112460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11282
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850228
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867311
receptor binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K04704273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73329
BRD-K04108962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33934
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.94605
natural killer cell activation	GO Biological Process Annotations 2015	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vitamin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39265
VMRC-LCD	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
studies	GeneRIF Biological Term Annotations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09285
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45201
aco1	GeneRIF Biological Term Annotations	1.0	null
ifns	GeneRIF Biological Term Annotations	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93248080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31921
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53387776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53838
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10478
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70945
BRD-K37145632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04158
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20545
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22807
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02111
solasodine-6025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41191
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11631946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26954
developmental process	GO Biological Process Annotations 2015	1.0	null
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ternary	GeneRIF Biological Term Annotations	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.22865
BRD-K89660028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22669
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
U-87-MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0553
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4995
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66218
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0391
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46746
LB1047-RCC	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14916
BRD-K20530300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35677
SNU-449	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040088
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21153
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2995
cellular response to virus	GO Biological Process Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSHR	MSigDB Cancer Gene Co-expression Modules	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGFR_OE_GDS1925_167_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5987
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.489
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26292
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040444
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.59945
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86658
BRD-K42199095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19627
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.05725
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06489
KARPAS422	DepMap CRISPR Gene Dependency	1.0	4.34152
MALME3M	DepMap CRISPR Gene Dependency	1.0	5.90316
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98039
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
heterotrimeric	GeneRIF Biological Term Annotations	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1535
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03615
Vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
CRCGN008_HEPG2_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0034
BRD-K04508260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5735
Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7682
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2844
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.006
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5951
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-892b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75242
BRD-K05250921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00291
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-8192-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.16015
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17108
superfamily	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79658624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40251
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41191
SCC4	DepMap CRISPR Gene Dependency	1.0	4.87678
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9763
Vitamin B12 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
BRD-K41604824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66958
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05064
20460173-ImmPortInterferons	GeneSigDB Published Gene Signatures	1.0	null
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.093
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
3-nitropropionic acid-6367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4942
SNU46	DepMap CRISPR Gene Dependency	1.0	2.19353
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.70395
BRD-K52119965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16255
MPP89	DepMap CRISPR Gene Dependency	1.0	2.5896
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
G82348BZ	GlyGen Glycosylated Proteins	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
BRD-K30799912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05574
Congenital amegakaryocytic thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22789469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30993
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57099
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t cell aggregation	GO Biological Process Annotations 2015	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8951
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.346298
cytokine activity	GO Molecular Function Annotations 2023	1.0	null
Adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
BRD-K03855997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36741
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9751
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48251
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876791
H9	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59477
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.9701
BRD-A81407814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57523
LB2241-RCC	COSMIC Cell Line Gene CNV Profiles	1.0	2.15839
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72146456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30348
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42986
BRD-K11105500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56906
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
BRD-K15615178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12665
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04313
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.60324
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.95416
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28027
Kidney Chromophobe_KICH_TCGA-KL-8331-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interferon-mediated signaling pathway	GO Biological Process Annotations 2023	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2817
IHH-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K19139070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74909
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876791
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A6ZA-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08302
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
multiorgan	GeneRIF Biological Term Annotations	1.0	null
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K06208179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.17405
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
insight	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C6-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44893
appear	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC59	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56978
Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15684061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15647
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell activation	GO Biological Process Annotations 2015	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7787
Myasthenia gravis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6014
ascorbic acid-3225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chloropyrazine-5750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFNAR2	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17765399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17277
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16096
response to virus	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41526
Chronic mucocutaneous candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.401
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12693
BRD-K28320832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09729
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BICR78	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K24166534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54032
H2595	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18966
BRD-K86774687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00883
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
natural killer cell activation	GO Biological Process Annotations 2023	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.36512
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891335
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YQ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-338-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	2.27655
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
p2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
response to external biotic stimulus	GO Biological Process Annotations 2015	1.0	null
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K35727000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1709
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7928
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0504
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06155
OCUM1	DepMap CRISPR Gene Dependency	1.0	3.58036
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08725
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44359
NR2F2_01_89	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61049
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4778-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
B cell proliferation	GO Biological Process Annotations 2023	1.0	null
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.73504
bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202946
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05382
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M8-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11436
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
B cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97338
KMBC2	CCLE Cell Line Gene Expression Profiles	1.0	1.44323
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85916
cell adhesion	GO Biological Process Annotations 2015	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.939469
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6493-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02446
BRD-K29784863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35436
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47437
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3425
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23835
positive regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19229
components	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of peptidyl-serine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23073
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77731
response to dsRNA	GO Biological Process Annotations 2025	1.0	null
S117	CCLE Cell Line Gene CNV Profiles	1.0	1.84157
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7958
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oral candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.96417
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99406
positive regulation of peptidyl-serine phosphorylation of STAT protein	GO Biological Process Annotations 2023	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8641
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-1.80317
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01624
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57426
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47884
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
CAL-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3060320__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Thymic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826079
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33696
Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845223
antiifnomega	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14542
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.711
IRF1	ChEA Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07877
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0466
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4614
SNU1040	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83005
BRD-K16727544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85478
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887597
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1837
Lung adenocarcinoma_LUAD_TCGA-44-2657-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K81457218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0333
hsa-miR-655	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39307
BRD-K50716325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16659
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58775
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Keratoconjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
BRD-K70978931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00862
NCIH1373	CCLE Cell Line Gene Expression Profiles	1.0	1.66396
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.82007
Uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90957
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6824
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46255
PMC8256365-JCMM-25-6373-s003.xlsx-ONECUT1_KEGG_JAK_STAT_SIGNALING-PROBE_ONECUT1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998641
DAOY	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25285
BRD-K78297750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02316
BRD-K25330450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66508
NCIH1437	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27049
PEER	CCLE Cell Line Gene Expression Profiles	1.0	2.23139
immune system process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
melanoma; nevus; skin neoplasms	GAD Gene-Disease Associations	1.0	null
KYSE140	CCLE Cell Line Gene CNV Profiles	1.0	1.98738
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2396
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4286
BRD-K69854611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02568
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06415
cytokine receptor binding	GO Molecular Function Annotations 2015	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36161
B cell activation	GO Biological Process Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75039
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01665
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64954
differentiate	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular ketone metabolic process	GO Biological Process Annotations 2015	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931079
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	8.54539
b cell proliferation	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56395592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06082
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01856
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	1.70426
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.635
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09568
BRD-K72707702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43664
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-mono_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.297
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9195
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58574
Parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89592
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6478
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
COGN305	DepMap CRISPR Gene Dependency	1.0	4.34451
type I interferon-mediated signaling pathway	GO Biological Process Annotations 2025	1.0	null
MDA-MB-231	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K31936306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19268
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60104
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37916
BRD-K43295075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41449
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6798
pathways	GeneRIF Biological Term Annotations	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30944
D-392MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.614
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K28006645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30823
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.07996
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850007
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BL-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06489
Gastroenteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8375
BRD-K77144444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23595
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373118
WISH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01624
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8618
DK-MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924074
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36571
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55679243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04422
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05699
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4267
Dental enamel hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
BRD-K01237500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.38673
ifnalpha2	GeneRIF Biological Term Annotations	1.0	null
Chodhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
BRD-K94580242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0944
BRD-K71672234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01221
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99216
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interferon alpha/beta/delta	InterPro Predicted Protein Domain Annotations	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
response to chemical	GO Biological Process Annotations 2015	1.0	null
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1803
BRD-K91268803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59954
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7662
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65384
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.836263
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76025
crystal	GeneRIF Biological Term Annotations	1.0	null
type i interferon receptor binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K64698045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48343
BRD-K35491869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19687
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
response to exogenous dsRNA	GO Biological Process Annotations 2023	1.0	null
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00096
response to exogenous dsrna	GO Biological Process Annotations 2015	1.0	null
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17449
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2054
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36032
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K44828787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00356
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.215
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
life	GeneRIF Biological Term Annotations	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5828
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to type I interferon	GO Biological Process Annotations 2023	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adaptive immune response	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29211776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0898
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88673
BRD-K41311678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27429
CMK86	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93148
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932728
WM793	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20907
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.31767
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16255
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.94693
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8597
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40718
unique	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86472
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044507
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64159
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
fenoprofen-3612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.539
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90828
BRD-K01286616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35023
Actin cytoskeleton-regulatory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REH	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070111
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34155
regulation of cell cycle	GO Biological Process Annotations 2025	1.0	null
response to dsRNA	GO Biological Process Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63191
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
fluvoxamine-2913	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44281
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25052
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
BRD-K95435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84742
BRD-K81669067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27981
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHT-101	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61139
BRD-K39411863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76059
BRD-K20160406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56261
BRD-K26543702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99048
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hepatitis c; remission, spontaneous	GAD Gene-Disease Associations	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8613
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53008
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17352
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92952
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31125
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945633
Interferon regulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.217
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50210179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0706
T cell activation involved in immune response	GO Biological Process Annotations 2025	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3109
BRD-K84879982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2015
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02707
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04634
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
BRD-K41731469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32967
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33248
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.936
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02278
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25641
vanoxerine-5702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24170552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50071
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03312699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13628
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39988
pioglitazone-5925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	3.82057
PF-382	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01544
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0478
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A180-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8189
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877286
20460173-ImmPortCytokines	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21509
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33448
BRD-K15341710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90079
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.9946
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02111
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840872
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92186
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96982
jak stat signaling pathway	KEGG Pathways	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995559
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1628
b cell differentiation	GO Biological Process Annotations 2015	1.0	null
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cytokine	GeneRIF Biological Term Annotations	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.683111
BRD-K81949875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43977
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7487
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876588
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6579
cell cycle process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
palmatine-2795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33409
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7376
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16183
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053012
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4693-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT3H	MSigDB Cancer Gene Co-expression Modules	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3028
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81682
HS611T	CCLE Cell Line Gene Expression Profiles	1.0	1.61416
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09752
EZH2	ENCODE Transcription Factor Targets	1.0	null
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Thymus gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4269
response to organic substance	GO Biological Process Annotations 2015	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88213
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DB-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71986
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2489
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3913
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16017
NCIH838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51853
structures	GeneRIF Biological Term Annotations	1.0	null
CMK115	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64439
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053134
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10406
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919617
BRD-K49031847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28646
Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
defense response to other organism	GO Biological Process Annotations 2015	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01980291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44358
PMC7481169-277_2020_4194_MOESM9_ESM.xlsx-RUNX1_R139G-RUNX1_R139_mutant_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84S-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.67829
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multi-organism process	GO Biological Process Annotations 2015	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	4.36229
response to other organism	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
pigmentation	GeneRIF Biological Term Annotations	1.0	null
BRD-K34531548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13799
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03634
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KS-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5548
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27049948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13913
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44534
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12402
JHOS-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
LC4-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BV173 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.72264
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14395
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826298
lymphocyte proliferation	GO Biological Process Annotations 2015	1.0	null
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09711
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2031
Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0533
KS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71111
HCC70	DepMap CRISPR Gene Dependency	1.0	3.52284
NCI-H747	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7001
NCI-H1437	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.26484
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99248
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2212
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92265
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78057
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07113
Teeth hard tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3859
PMC9859931-mmc5.xlsx-MSC_ADP_pred-perturbagens-Targets_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52731672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68963
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04507
PMC3060320__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Metaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
response to exogenous dsRNA	GO Biological Process Annotations 2025	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.412
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6972
BRD-K98704738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15972
BRD-K94685203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02099
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9797
BRD-K01360791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03894
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.72785
lymphocyte proliferation	GO Biological Process Annotations 2023	1.0	null
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
roles	GeneRIF Biological Term Annotations	1.0	null
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93151
PMC8638098__F5	PFOCR Pathway Figure Associations 2024	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.527
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.790422
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068278
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274045
CAS1	DepMap CRISPR Gene Dependency	1.0	2.49801
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BRD-K19085288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74417
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7733
HS255T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28483
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31893
MAGEA9	MSigDB Cancer Gene Co-expression Modules	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97241181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01464
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6221
BRD-K85525164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03956
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4405
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40561
hsa-miR-3973	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29931
BRD-K78886448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63089
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.035
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
BRD-K87167435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38918
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
MDM2	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K73462370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27181
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20164
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38282
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88093
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4506
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956454
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41305
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K51525251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71688
PMC10245467-mmc3.pdf-250-ZNF888_ZNF888	Rummagene Transcription Factor Associations 2026	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2819
BRD-K63859730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28347
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
15-delta prostaglandin J2-5228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3487
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.58416
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.80603
BRD-K22390389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60281
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
BRD-K02061146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69431
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0926
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5347
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.59204
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.83915
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8156
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Addison's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.245
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.47815
BRD-K35639494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40577
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850007
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58343
Plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37548
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bladder	GTEx Tissue Gene Expression Profiles	1.0	0.949277
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850559
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8889
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04373
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32629
CRCGN013_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19116
Narcolepsy	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30195
single	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU1	CCLE Cell Line Gene Expression Profiles	1.0	1.57677
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22378
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066209
narcolepsy	GAD Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cataract 9 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.691
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04462
BRD-K42754852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24396
NALM-6	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25858
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922474
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3481
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7188
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863679
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33711
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4454
MAP2K7	MSigDB Cancer Gene Co-expression Modules	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050906
BRD-K76210487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09511
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
HCC56	CCLE Cell Line Gene CNV Profiles	1.0	1.502
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23087
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86494
BRD-K84636055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29857
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A3L1-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
a72	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
BRD-K65107903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93565
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050955
into	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047434
Lung adenocarcinoma_LUAD_TCGA-86-8074-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5575-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0468
Pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49453
BRD-K65445351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19112
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78329
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9869
CRCGN015_MCF10A.WT.HP_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04118
BRD-K49298555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88596
BRD-K90019187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06619
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27853
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854337
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1601
innate immune response	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
helpful	GeneRIF Biological Term Annotations	1.0	null
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62215
BRD-K30462643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08481
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0648
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
T cell activation involved in immune response	GO Biological Process Annotations 2023	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2157	CCLE Cell Line Gene CNV Profiles	1.0	1.85234
REH	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45333
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883463
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14923
response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MM-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32324
BRD-K96389533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07952
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.175
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5226
JHH7	DepMap CRISPR Gene Dependency	1.0	8.02324
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of peptidyl-serine phosphorylation	GO Biological Process Annotations 2015	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHK1_KD_GSE54267_671_human_U2OS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A83387524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15674
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7334
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ACHN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43479
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9786
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907977
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4357
response to dsrna	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D-336MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2866
Kidney Chromophobe_KICH_TCGA-KL-8326-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58574
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Chlorosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
Thymic medullary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	2.0645
ONS-76	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
aps	GeneRIF Biological Term Annotations	1.0	null
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95307
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98416
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.632
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52945
Lung adenocarcinoma_LUAD_TCGA-55-7907-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29756429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64539
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
skin	GTEx Tissue Gene Expression Profiles	-1.0	-1.17949
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.929641
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7553
Four-helical cytokine, core	InterPro Predicted Protein Domain Annotations	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991408
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BRD-K48147099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35547
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.59978
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05075
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0365
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
T cell activation	GO Biological Process Annotations 2023	1.0	null
napelline-2522	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Stomatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19785
Thymic medullary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NUGC3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.98735
indometacin-2377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K11269634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26831
BRD-K04791118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18228
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	1.01389
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q9-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.30978
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytokine-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T5-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
leukocyte activation	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.64315
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40633
GSU	DepMap CRISPR Gene Dependency	1.0	4.15746
BRD-K82397896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19065
496100667_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12332
mononuclear cell proliferation	GO Biological Process Annotations 2015	1.0	null
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5665
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.1624
extracellular space	GO Cellular Component Annotations 2015	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1726
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.732565
BRD-K02823077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17139
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1586
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09468
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04875192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6562
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.75207
protein binding	GO Molecular Function Annotations 2015	1.0	null
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3444
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.8601
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67217
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9974099-jci-133-147087-s013.xlsx-Receptor_GBM__ligand_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
modes	GeneRIF Biological Term Annotations	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38861
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.84284
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.853749
BRD-K76713927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13402
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.49045
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K97064059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77789
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
hsa-miR-1264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585224
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8177
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23073
BRD-K94751306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09716
Nail disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.311
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5903
496100481_PCx_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32078
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60030763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14764
PMC9437808-mmc5.xlsx-Upstream_regulators-IPA_Upstream_regulator_analysis_genes_that_were_downregulated_in_the_cf-mRNA_of_AZD_treated_group_at_2-hour_post_LPS_time_point_were_used_as_inputs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
valdecoxib-6378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5609
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70657
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74215
Prostate adenocarcinoma_PRAD_TCGA-HC-8266-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13768
BRD-K26074237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04555
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cell cycle	GO Biological Process Annotations 2023	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64815
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880051
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7681-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytokine activity	GO Molecular Function Annotations 2025	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63272
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
EPHA4_drugactivation_229_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.48708
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42042
CRCGN017_MCF10A.TP53.M_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02632
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7143
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13414
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07735
leukocyte cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
PMC9730246-Table_7.xlsx-LPS_Val_up-Upstream_Regulator_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MKN45	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51045
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01816
Lip disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
H2591	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Thymic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
Overview of proinflammatory and profibrotic mediators	WikiPathways Pathways 2024	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
Perturb_4399_KO_STING1_SRP191307	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.787
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867311
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	3.94934
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1875
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931079
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34227
PMC9974099-jci-133-147087-s013.xlsx-Receptor_GSC__ligand_GBM-Ligand_expressed_in_GBM_CAF_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02273
Pernicious anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.72245
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.933
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3465
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05798
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1275
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.05372
Autoimmune polyendocrine syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.614
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14352
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31729
BRD-K83090041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06387
regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
COLO679	DepMap CRISPR Gene Dependency	1.0	2.19481
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26404
diseases	GeneRIF Biological Term Annotations	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
SNU620	CCLE Cell Line Gene CNV Profiles	1.0	1.44105
Sarcoma_SARC_TCGA-SI-AA8B-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01894374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41324
CTCF	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66968
IL4	MSigDB Cancer Gene Co-expression Modules	1.0	null
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01535
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MDBK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828877
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94623
immune response	GO Biological Process Annotations 2015	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
BRD-K91712163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11108
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.03549
Spev	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4047
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27168
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.61355
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular response to cytokine stimulus	GO Biological Process Annotations 2023	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943196
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22628
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9984
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4707
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97839
PTPRB	MSigDB Cancer Gene Co-expression Modules	1.0	null
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253908
Plastid inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30059
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876791
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508635
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8761
BRD-K53748177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10868
natural killer cell activation involved in immune response	GO Biological Process Annotations 2023	1.0	null
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39355
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01323
Adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53923
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20486
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
JURKAT	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.59692
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4158-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E8-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07909
19802007-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2085
number	GeneRIF Biological Term Annotations	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36677
defense response	GO Biological Process Annotations 2015	1.0	null
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10259
complexes	GeneRIF Biological Term Annotations	1.0	null
WM1552C	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K01772946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98406
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24636
BRD-K74948793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11164
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4679
IFNA1	MSigDB Cancer Gene Co-expression Modules	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051076
BRD-K90808566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53389
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.48912
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
hsa-miR-374c	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8267
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K51754677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01365
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8224
BRD-K99447506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21326
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8015
hsa-miR-4484	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K95543908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34854
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0675
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13865
Hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
among	GeneRIF Biological Term Annotations	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0779
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
DKMG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50703
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.58174
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28835
leukocyte aggregation	GO Biological Process Annotations 2015	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051207
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37456
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92045
cell proliferation	GO Biological Process Annotations 2015	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95959
GSE239844_7_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
azaperone-3573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.38478
Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30227
BRD-K22610673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51453
KYSE450	CCLE Cell Line Gene CNV Profiles	1.0	1.63924
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1518
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33831
MDAMB468	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64182
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61115
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053135
leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.39959
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.24952
BRD-K30785989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33482
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33061098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.01959
BRD-K84099887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13294
LPS6	DepMap CRISPR Gene Dependency	1.0	2.09841
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95917
MUTZ5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80395
LAMA-84	GDSC Cell Line Gene Expression Profiles	1.0	1.54098
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
15208663-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61984
cytokine receptor binding	GO Molecular Function Annotations 2025	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.48516
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41042
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11377
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12109
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64869
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47101
BRD-K27726273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12815
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Peritonitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
LIVF001-002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73356
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30815
cytokine-mediated signaling pathway	GO Biological Process Annotations 2023	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38069
sitosterol-4154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
natural killer cell activation involved in immune response	GO Biological Process Annotations 2025	1.0	null
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.46008
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20407
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.723691
Skin Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
BRD-K45909830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89983
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.02508
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21775
BRD-K83487481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27656
Phycobilisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
Omenn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95854
ATF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05708
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7291
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A624-01A-22R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.867551
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68445
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CM-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08279
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0969
HS766T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57877
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4389
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18031793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49966
myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218374
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3333
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.57181
BRD-K44622259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07223
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_AT1-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78262424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03233
aire	GeneRIF Biological Term Annotations	1.0	null
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.58734
cytokine cytokine receptor interaction	KEGG Pathways	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8483
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14699
Chloroplast inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
380 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854337
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6909-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	5.85157
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1014
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
lymphocyte differentiation	GO Biological Process Annotations 2023	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.706969
BRD-K10704442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.70277
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876588
cellular process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825692
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune polyendocrine syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.401
U-118-MG	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37428
BRD-K29936219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71518
BRD-K64165176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31528
type	GeneRIF Biological Term Annotations	1.0	null
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.16254
MIA-PACA-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of peptidyl-serine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066161
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850228
BRD-K13076765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70Q-01A-13R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19072
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47665
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92735
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36245
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.34804
single organism cell adhesion	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
iocetamic acid-4425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
humoral immune response	GO Biological Process Annotations 2015	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3105
BRD-K44298652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70631
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K20735575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56452
IRF1-21803131-MONOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAGEA8	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K13941052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74033
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K90644597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24258
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16507
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07583
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051186
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI15A	DepMap CRISPR Gene Dependency	1.0	5.89832
BRD-K39685923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71645
cell activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
nucleotide	GeneRIF Biological Term Annotations	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
upregulation	GeneRIF Biological Term Annotations	1.0	null
15208663-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
response to biotic stimulus	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTSB	MSigDB Cancer Gene Co-expression Modules	1.0	null
natural killer cell activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13623
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17045
architectures	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93524
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09769
BRD-K74767736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40815
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.6372
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8954
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DSH1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
HS936T	DepMap CRISPR Gene Dependency	1.0	2.66133
Sarcoma_SARC_TCGA-DX-A6BG-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21143905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44646
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59030325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28246
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6755
positive regulation of peptidyl-serine phosphorylation	GO Biological Process Annotations 2015	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
BRD-A14424697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22386
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
AR	ChEA Transcription Factor Targets	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
leukocyte activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
leukocyte proliferation	GO Biological Process Annotations 2015	1.0	null
hsa-miR-548an	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99525
Thymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
additional	GeneRIF Biological Term Annotations	1.0	null
BRD-K43026564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20633
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41701
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0691
BRD-K92167240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01769
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
t cell activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0111
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dihydroergotamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55136
Parkin_OE_GDS4476_55_human_U87MG	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sarcoma_SARC_TCGA-K1-A6RV-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	4.52021
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5123
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21856
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
BRD-K89175823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42684
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20287
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14751
natamycin-3548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
BRD-K68205606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50813
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G31685JQ	GlyGen Glycosylated Proteins	1.0	null
PMC6187090-mmc1.xlsx-TP53_negative-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
B cell activation	GO Biological Process Annotations 2023	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947986
negative regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3460-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47599758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08386
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of peptidyl-serine phosphorylation of STAT protein	GO Biological Process Annotations 2023	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889343
TC138	DepMap CRISPR Gene Dependency	1.0	3.61281
THPO	MSigDB Cancer Gene Co-expression Modules	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.42797
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.144
RS4-11	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.8541
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9062
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37917
conserved	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1977
T cell activation	GO Biological Process Annotations 2025	1.0	null
Autoimmune gastritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Nitrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
BRD-K67980271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09987
SCC-9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64111
BRD-K97729706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48817
GSE155031_5_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K33151492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37209
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904502
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57942
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.92717
K-562	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
hsa-miR-4470	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K20030272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97108
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.994259
NCIH1355	DepMap CRISPR Gene Dependency	1.0	2.53249
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61079
127399	DepMap CRISPR Gene Dependency	1.0	3.59032
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08769
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.86694
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6656
NCI-H2228	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
SU8686	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
TP63_01_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.66713
BRD-K35879814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70516
BRD-K92941354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0226
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01624
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
antibodies	GeneRIF Biological Term Annotations	1.0	null
AURKB_knockdown_92_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81259
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2542
GB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56362
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
BRD-K73227372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59683
cellular response to type I interferon	GO Biological Process Annotations 2025	1.0	null
NFYB_01_238	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66786
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48564
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A16760970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16547
cytokine receptor binding	GO Molecular Function Annotations 2023	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5363
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41499
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
signature	GeneRIF Biological Term Annotations	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.992
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2281
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.01431
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876588
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.43146
positive regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.850007
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
positive regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912394
BRD-K76485827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41795
BRD-K69826976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16726
NCIH647	CCLE Cell Line Gene CNV Profiles	1.0	1.83982
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4892-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
containing	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20105
BRD-K21648400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36408
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
NCIH23	CCLE Cell Line Gene Expression Profiles	1.0	1.57063
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52218
Rad17 RFC-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.084
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.85882
BRD-K68330990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08265
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69986
JURKAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45163
BRD-K13873561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33099
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Oophoritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Hepatitis C	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27425
PF382	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4307
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3197
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45111
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02816
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11519
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36614
skin	GeneRIF Biological Term Annotations	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891335
BRD-K94196749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10626
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97319
AM-095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01615
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49226
Thymus cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.717
BRD-K17315445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36633
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0772
HS852T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.95502
b cell activation	GO Biological Process Annotations 2015	1.0	null
PMC3136489__F7	PFOCR Pathway Figure Associations 2023	1.0	null
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
FOSL1	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-M13639915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45251
BRD-K73145196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97513
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839971
Cytokine cytokine receptor interaction	WikiPathways Pathways 2024	1.0	null
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47541
terguride-5400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63949
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
autoimmune	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54626
NCI-H322M	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92517
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.71849
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
PF-00539758-00-6379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cytokine-cytokine receptor interaction	KEGG Pathways 2026	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03987
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRKCA	MSigDB Cancer Gene Co-expression Modules	1.0	null
A673	DepMap CRISPR Gene Dependency	1.0	2.31986
BRD-K50721666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38114
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4203
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43122
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.30896
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27303
cell cycle arrest	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877286
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.99059
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35628
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43553
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
biological regulation	GO Biological Process Annotations 2015	1.0	null
STOCK1N-35215-6380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BRD-K01285236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34765
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1755	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.15839
KASUMI1	DepMap CRISPR Gene Dependency	1.0	4.67768
SNU81	DepMap CRISPR Gene Dependency	1.0	3.10702
Critical COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6997
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16966765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12714
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72501910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04416
ICC4	DepMap CRISPR Gene Dependency	1.0	3.91159
DMS454	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87908
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
BRD-K05940224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.044
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5503
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08229
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75193
t cell activation	GO Biological Process Annotations 2015	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13113551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30808
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05729
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83304
BRD-K11117868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06126
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clopamide-5402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60159
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01671
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2251
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44812
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07406
BRD-K22534934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11376
Macular degeneration_Fibroblast_GSE1719	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45851
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0407
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4982-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-SNU-16	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.51569
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12142
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66437
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homotypic cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38568
15869706-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5915
DAOY	CCLE Cell Line Gene Expression Profiles	-1.0	-2.28527
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853553
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	2.75874
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
GATA1	ChEA Transcription Factor Targets	1.0	null
PMC10873402__F5	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K16940345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41532
Heinz body anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
NAMALWA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2333
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58885
Saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
NZOV9	DepMap CRISPR Gene Dependency	1.0	9.65308
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5104-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43918582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09258
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52782
ifn	GeneRIF Biological Term Annotations	1.0	null
AM-38	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.258
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
bephenium hydroxynaphthoate-5263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92432769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54386
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.448731
Nevus	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gingivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.119
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0918
BRD-K26709432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13512
BRD-K20897375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27213
BRD-K95500387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00128
BRD-K46015322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64416
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84035
interact	GeneRIF Biological Term Annotations	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308251
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33219
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Anal spasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5119-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.85032
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994697
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65079
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5439-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.53154
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H460	GDSC Cell Line Gene Expression Profiles	1.0	1.55427
Adrenal cortical hypofunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.228
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06125
B cell activation involved in immune response	GO Biological Process Annotations 2025	1.0	null
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08295
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02433
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17347
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.977836
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53592
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29369
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039276
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1591
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.973682
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1195
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60325
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50794
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K88720906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38184
BRD-K43284834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5968
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.30289
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51815
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8342
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069751
BRD-K72234025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28962
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61J-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.43121
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
BRD-K15940471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94354
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6129
indoprofen-3007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.86481
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858947
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8276
RERF-LC-SQ1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
positive regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K11625057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00208
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3271
MLLT10	MSigDB Cancer Gene Co-expression Modules	1.0	null
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71135
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.39776
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.80245
PMC7605689__F2	PFOCR Pathway Figure Associations 2023	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	2.7504
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08963
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.05835
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.076
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90616
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77191
c1344delc	GeneRIF Biological Term Annotations	1.0	null
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069707
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2483
recognition	GeneRIF Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7435
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0244
defense response to virus	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43381631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1852
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28122
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4740-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3394
HEL	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RIG-I-like receptor signaling pathway	KEGG Pathways 2026	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.06305
BRD-K05051664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40913
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.96001
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3835
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24251672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12588
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.85535
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	1.23726
HUP-T3	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
U138MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36807
BRD-K20023110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13444
OVCA420	DepMap CRISPR Gene Dependency	1.0	5.102
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06742
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22415
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05574
BRD-K76706127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89263
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	1.98007
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963256
BRD-K94903598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92663
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.10163
NCI-H838	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
culture supernatant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16575
cellular response to virus	GO Biological Process Annotations 2025	1.0	null
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
interferon-mediated signaling pathway	GO Biological Process Annotations 2025	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56470219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77398
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1867
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4074
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2027
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11313
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cutaneous Melanoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78257
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36407
Nso	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
single organismal cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64Q-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.05375
BRD-K95192796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12964
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77058
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4666-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96625
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.51079
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3401
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3193
LN-18	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
SNB19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65508
Liver hepatocellular carcinoma_LIHC_TCGA-O8-A75V-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ModE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.55629
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	1.46526
Brain Lower Grade Glioma_LGG_TCGA-W9-A837-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2373	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34445094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01073
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2173
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40652
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966996
Thymic dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4229
HCC1187	DepMap CRISPR Gene Dependency	1.0	2.55705
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1801
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9293
NUDUL1	CCLE Cell Line Gene Expression Profiles	1.0	2.87467
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4817
Four-helical cytokine-like, core	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32873
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K34534297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15711
MG-63	COSMIC Cell Line Gene CNV Profiles	1.0	2.15839
PEO1	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.77446
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0164
BRD-K31093279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39945
added	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90545
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44645