association	dataset	threshold value	standardized value
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28923
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00653
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06861
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16512
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30467
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18125
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
ABRAXAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3849
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832693
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.869074
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961876
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8808
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33778
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45124
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.840369
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12826
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12211
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
GSE131425_2_v_0_arg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
SNU308	DepMap CRISPR Gene Dependency	1.0	2.25285
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.75544
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17177
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04332
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29123
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29306
Perturb_1088_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.26682
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71186
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF772	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53409
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958498
RNF2	ENCODE Transcription Factor Targets	1.0	null
RASSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75948
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
ZFAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99516
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
LS411N	DepMap CRISPR Gene Dependency	1.0	3.24787
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16377
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9784
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRPF38A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90368
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12407
EIF4ENIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77114
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14543
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25653
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.18054
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48501
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967108
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19508
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039309
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053336
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
Perturb_17240_KO_SRC3_SRP390910	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61119
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
NCIH1836	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38804
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7995_KO_Drosha_SRP076184	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77871
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26019
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	3.85521
SPI1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF507	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59557
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38045
iga	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15481
Lung adenocarcinoma_LUAD_TCGA-99-7458-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999783
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00439
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3022
GAS2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81719
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93669
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995426
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30911
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12826
A-Vietnam-1203-2004(H5N1)_24Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78487
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.83553
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17023574-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969398
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
nci-h226br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512564
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112005
PANK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99661
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.625
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31279
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50792
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965411
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15006
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845643
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882374
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33907
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5744
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85242
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040506
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84988
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838984
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11052
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08402
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36998
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5037
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956774
immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364331
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105575
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33715
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5924
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877915
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50684
Acute Myeloid Leukemia_LAML_TCGA-AB-2818-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.24203
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881274
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51461
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5175
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.490538
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885088
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920404
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885319
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43436
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940296
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
ZBTB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15703
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51255
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32353
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908666
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26424
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888739
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070853
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55664
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3822
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95252
SARS-CoV_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72569
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2565
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69543
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04026
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847045
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TE125T	CCLE Cell Line Gene Expression Profiles	1.0	1.76752
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98424
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05113
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13003
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994871
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69641
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60864
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7037
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZN-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0009
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00708
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238706
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15339
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.3998
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882291
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900614
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19535
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12994
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24811
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36921
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38419
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973093
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9784
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21505
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977125
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75582
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13687
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4608
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59291
GTEx Colon 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	7.98814
PAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21614
ZNF804A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90888
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36112
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16228
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71769
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66437
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996637
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29658
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19392
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03244
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26108
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78733
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8874
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55823
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039385
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877345
EVI5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59448
ATP6V0A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52663
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5722
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53031
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	2.01938
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867245
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57946
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84817
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02984
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17901
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-K1-A42W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02162
NCIH2171	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57373
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01492
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8975
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43479
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31388
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3937
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844646
BICR16	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09735
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054816
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51506
production	GeneRIF Biological Term Annotations	1.0	null
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37099
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06294
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838379
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859396
GPR108	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44459
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3989
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86008
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63671
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15127
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33393
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1722
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53725
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.837903
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973252
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.796
stomach	HPA Tissue Protein Expression Profiles	1.0	1.47885
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45992
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27309
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58448
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22499
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3021
CPEB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32933
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24726
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877741
Perturb_10720_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.60504
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33083
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82824
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882415
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57228
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09397
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.026
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94821
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2218
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49797
LCAM1	DepMap CRISPR Gene Dependency	1.0	4.06285
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hESC_Derived_CD184+_Endoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.834346
mesenteric lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485935
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890435
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06994
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71039
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66254
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01083
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04278
KYAE1	DepMap CRISPR Gene Dependency	1.0	6.68375
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897349
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07175
ORMDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99664
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46478
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882168
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5269
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16219
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_184_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.44136
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62971
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87144
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57349
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02529
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33598
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51951
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45164
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36553
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938728
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64061
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890427
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873912
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863456
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3783
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4337
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEx Colon 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	20.7477
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36426
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30845
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09183
SARS-BatSRBD_96Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68584
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0323
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43571
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4069
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5035
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03443
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11516
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03693
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27787
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842525
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18442
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21204
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52683
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7062
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20907
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47821
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41888
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29726
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.669417
switch	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11393
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52309
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.921483
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0261
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53987
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97412
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130956_2_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05145
C11orf71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18014
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858465
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12826
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50816
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56811
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979261
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82688
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09453
PMC4777381-pone.0150624.s007.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1195	CCLE Cell Line Gene Expression Profiles	-1.0	-2.69863
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69767
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03272
Perturb_3324_KO_Tkt_SRP364774	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74317
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04634
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ING2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35527
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	5.37896
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20788
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03602
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.21655
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU182	DepMap CRISPR Gene Dependency	1.0	4.71364
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.96882
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.83499
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827637
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.59248
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860048
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993674
SH10TC	DepMap CRISPR Gene Dependency	1.0	5.15652
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962604
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5842
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917478
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03782
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.62407
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.837915
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5992
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47092
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79557
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24653
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30915
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16686
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960473
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00675
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21797
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29952
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965067
GSE160304,GSE163392_0_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.02678
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86258
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
GATA1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06125
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162341
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15717
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83538
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27341
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4554
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.07945
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962483
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28833
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9052
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17692
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71954
ZNF773	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29087
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2665
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2591
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41185
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60129
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1461
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55783
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02564
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90494
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79327
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11583
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0612
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039554
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3238
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27075
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66653
cervix, uterine	HPA Tissue Protein Expression Profiles	1.0	0.781809
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954788
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973077
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48662
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
GSE144484_2_v_3_mllt6_human	RummaGEO Gene Perturbation Signatures	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94656
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6941
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924805
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20916
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5012
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.990688
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835422
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77615
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41437
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09296
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.47885
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66306
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_36Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6332
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896733
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21699
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1685
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66878
RNASE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59858
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12942
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884634
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8961
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32257
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.623102
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07778
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24214
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1671
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50846
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.59754
SARS-dORF6_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40171
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890554
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02323
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54386
EMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44225
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.899741
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990258
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833481
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971398
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43993
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48807
TK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47883
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.050097
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1248
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06753
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29552
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847871
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.24461
C8orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69898
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3132
CGTHW1	CCLE Cell Line Gene Expression Profiles	1.0	1.66166
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916027
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RS5	CCLE Cell Line Gene Expression Profiles	1.0	1.67551
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893946
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38633
KOPN8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94582
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15507
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2934
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65729
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45382
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18554
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54498
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.289
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41089
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942212
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02323
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
GSTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87494
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57323
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239913
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4771
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3002
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	8.79826
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
GSE139992_2_v_3_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7001
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938555
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28374
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	1.34713
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06425
Perturb_6215_KO_Hdac1_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.85381
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38286
GSE65617_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99978
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8959
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062062
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61427
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52022
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4878
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1626
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.08571
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42566
SARS-CoV_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.58176
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39959
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36475
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.948599
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39047
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051559
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980013
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49683
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00108
SARS-CoV_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95213
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27834
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1428
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36879
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69638
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29016
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF776	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71584
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5238
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069132
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41327
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
Perturb_18112_KO_Eed_SRP132909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.37207
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.969
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976177
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.61212
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937764
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19134
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847946
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22723
DTWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72602
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2383
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74867
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30761
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ELMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15141
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75431
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947279
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875992
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6645
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.958
Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07855
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71547
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32838
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32982
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00539
PMC10879698-mmc1.pdf-12-ZXDC_ZXDC	Rummagene Transcription Factor Associations 2026	1.0	null
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0888
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5016
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62887
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
T173	CCLE Cell Line Gene Expression Profiles	1.0	1.74312
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32491
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27531
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876353
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79004
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23198
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	5.80604
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0835
IGF1R_druginhibition_46_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.07623
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14111
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69847
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9768
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05894
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06609
SSU72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56499
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.198
RBPJ	ChEA Transcription Factor Targets	1.0	null
CSNK1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52118
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
FOXP1	ChEA Transcription Factor Targets	1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05381
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881274
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95436
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55386
stimulation	GeneRIF Biological Term Annotations	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905478
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68259
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151782_3_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05319
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01592
YH13	CCLE Cell Line Gene Expression Profiles	1.0	1.48052
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053827
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873864
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24514
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11621
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.338
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.01508
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51363
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.885332
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8332
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97426
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25445
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64828
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27027
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53225
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44597
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_12Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58625
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04388
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2992
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84326
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09935
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06893
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.857366
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11038
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871983
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHROOM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86217
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52133
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867955
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896955
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95468
perinatal necrotizing enterocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05723
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25105
hsa-miR-548l	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61605
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.908257
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60573
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.2
naive	GeneRIF Biological Term Annotations	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829381
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16948
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67186
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02834
NCIH157DM	DepMap CRISPR Gene Dependency	1.0	2.20917
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2E-MSC_up_specific-Supplementary_Data_2E_-_expression_of_up-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3212
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08142
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-585-ADNP2_ADNP2	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.1497
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39038
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17835
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044308
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82437
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08196
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23941
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2718
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6322
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29344
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95018
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
H3K36me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77589
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13389
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NKX6-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06144
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3791
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52012
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24262
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6914
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14402
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11703_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.02085
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32323
CCDC142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54606
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38379
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877345
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885864
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992097
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5044
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185519_4_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1591
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11401
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78026
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77622
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64228
MM160113	DepMap CRISPR Gene Dependency	1.0	4.90035
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15904
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904493
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966759
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972072
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22282
FAM43B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.451
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87667
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21506
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04038
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_228_KO_Lmx1b_SRP194283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6688
SW1573	CCLE Cell Line Gene CNV Profiles	1.0	1.331
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6724
ACTL6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99393
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25907
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.74521
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12826
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28709
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77379
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40991
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07376
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13108
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846417
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66722
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23556
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30095
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57518
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857547
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36319
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32834
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24137
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21506
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22102
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.66448
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13278
GSE205070_1_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4621
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863234
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29438
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98622
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20539
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95018
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053159
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16033
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20327
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939656
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93763
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6171
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89102
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68827
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63306
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62051
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14025
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864267
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31475
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932135
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40605
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04408
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.6058
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97062
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29552
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54463
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82734
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28256
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60056
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0767
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990276
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6348
Steatocystoma multiplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10428
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10062
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59007
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98126
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	0.882513
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946025
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18746
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929113
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857632
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22197
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00525
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27447
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845506
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45228
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938526
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912308
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64772
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36142
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87203
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892647
TAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59862
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04542
E2F4	ENCODE Transcription Factor Targets	1.0	null
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8629
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.908393
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03659
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.7663
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10751
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944841
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_4_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221061
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10238271-41388_2023_2678_MOESM8_ESM.pdf-3-PAX5_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49736
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24387
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
TMEM222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56161
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47854
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29043
UBL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93928
TN2	DepMap CRISPR Gene Dependency	1.0	2.60283
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04611
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01405
EXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79295
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13998
brain	HPA Tissue Gene Expression Profiles	1.0	2.23957
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77033
LNCaP clone FGC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0244
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.874391
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045622
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824793
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22492
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12614
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02437
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928259
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29372
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0219
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72213
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65746
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81402
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895394
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10354
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79512
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0981
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97479
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75232
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04799
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
SARS-dORF6_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80366
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847697
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0343
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60938
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3973	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx Lung 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.16905
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18047
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59097
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
RNPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.587
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.47885
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5057
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34306
PLEKHG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35389
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830874
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07841
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82703
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35186
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55098
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47365
SNUC1	DepMap CRISPR Gene Dependency	1.0	3.13422
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13146
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08701
Prostate adenocarcinoma_PRAD_TCGA-G9-6367-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64096
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827334
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890802
Brain capillary endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
SLC25A22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72227
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35589
SGTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36451
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29296
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962483
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00046
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946109
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08316
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.31
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.919769
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46878
PPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65057
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.34319
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041153
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
Lung adenocarcinoma_LUAD_TCGA-78-7537-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36561
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.89574
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22096
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01559
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50759
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.18944
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13004
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8651
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0543
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843521
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73448
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917829
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861751
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02596
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5271
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20057
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47942
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21619
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9664
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49058
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31057
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22082
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910949
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86404
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.920722
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53629
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46387
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01765
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962483
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCM8-MCM9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875992
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12826
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8649
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20406
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884019
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18517
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908376
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM24_knockout_300_GSE19675	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.98669
EXOSC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90188
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9076
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51026
HECTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94301
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4568
KCTD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57171
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6991
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26778
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92829
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874593
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.18332
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30419
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17767
GATA5_KO_GSE47425_50_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59443
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
DMS454	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6816
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875851
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87516
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.48495
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.30852
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26401
METTL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44323
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16944
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06053
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962483
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18298
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28439
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
FHIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86227
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46503
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.33431
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18663
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54436
IDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66847
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052468
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947928
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03989
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51109
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830334
HTT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03549
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16668
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949165
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48567
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55568
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60362
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885864
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65872
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119564_2_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
Peyer's gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00255
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05106
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836528
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909826
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058048
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.937464
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37969
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51666
SAP30	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53883
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92231
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2087	CCLE Cell Line Gene Expression Profiles	1.0	1.55468
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.47885
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18135
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04894
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02817
Perturb_2270_KO_lincBrn1b_SRP028547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
drives	GeneRIF Biological Term Annotations	1.0	null
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32458
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.865562
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.15456
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13223
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25241
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6959
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02277
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01205
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9878
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974137
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5549
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68291
18714397-TableW1	GeneSigDB Published Gene Signatures	1.0	null
SETD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35411
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
Octamer	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QM-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8816
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.07525
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19392
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0962
SPRYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45485
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57381
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.3647
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.58611
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08714
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12788
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18079
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83573
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69522
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923322
X-linked intellectual disability-short stature-overweight syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901584
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8314-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08237
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6879
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958911
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00117
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925616
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868704
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.915987
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09439
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942476
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9286
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930724
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89982
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35496
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46797
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34434
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9007
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15133
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.877345
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0837
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73601
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38048
OC314	DepMap CRISPR Gene Dependency	1.0	2.44022
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.318
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4079
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.967022
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.726
Cavum septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8305C	DepMap CRISPR Gene Dependency	1.0	4.57554
Perturb_11704_KD_MIR31HG_SRP051359	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.77163
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8718
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66102
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
Hyperphosphatasia with impaired intellectual development syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0877
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18338
nt2d1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906744
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3701
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17715
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.07991
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25951
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
X31(H3N2)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.29723
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93831
Swine influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06272
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34175
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.451
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17285
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905174
PLD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04502
H3K79me2_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.58818
Sarcoma_SARC_TCGA-DX-A6YS-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51247
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27509
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01175
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70021
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4686
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987333
KDM5B	ENCODE Transcription Factor Targets	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.06952
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87366
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860217
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80353
FADS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72995
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24233
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85948
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35982
DOTC24510	DepMap CRISPR Gene Dependency	1.0	2.93576
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56646
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.956
icSARS CoV_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88256
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57996
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7831-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125007,GSE125008_10_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12119
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055378
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959015
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6658
KBTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94541
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72948
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89636
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8332
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65374
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16874
HS739T	CCLE Cell Line Gene Expression Profiles	1.0	1.79995
FTC238	CCLE Cell Line Gene CNV Profiles	1.0	1.53311
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20178
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847084
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81873
LS123	DepMap CRISPR Gene Dependency	1.0	2.60678
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1656
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41833
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46886
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44551
Autosomal dominant distal hereditary motor neuronopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19775
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.02155
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984402
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3354
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73164
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86881
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14083
skin	GTEx Tissue Gene Expression Profiles	-1.0	-0.894168
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18557
HS895T	CCLE Cell Line Gene Expression Profiles	1.0	2.17922
TALL1	CCLE Cell Line Gene Expression Profiles	1.0	1.51662
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53968
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47228
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0598
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92189
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.968111
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33388
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36839
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26375
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91647
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62131
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09374
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42739
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17024
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41535
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041357
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04438
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11132
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38888
RAB3IL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08385
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6545
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05229
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57688
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13981
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269867
F36P	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53393
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23705
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829553
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36676
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29466
NOS1	DepMap CRISPR Gene Dependency	1.0	2.5073
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835303
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40497
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27388
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9182
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00001
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.36301
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837715
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9914
Perturb_6214_KO_Hdac_SRP227204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.65994
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19922
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92592
u266	HPA Cell Line Gene Expression Profiles	1.0	0.902873
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.010259
GATA3	ENCODE Transcription Factor Targets	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11529
SPI1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3835
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12592
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.4166
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70405
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.509
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04389
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.940422
APCDD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0901
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00168
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07506
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60114
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81139
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90822
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52221
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00191
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32857
nci-h226 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.203138
Perturb_9104_KD_KDM4C_SRP202026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.69811
RBL1_KO_GDS1932_739_mouse_Neurospheres	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980205
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44551
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865373
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09335
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23221
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25083
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30055
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26402
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32682
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.61366
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57934
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995894
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06926
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63789
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48703
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15109
JURKAT	CCLE Cell Line Gene Expression Profiles	1.0	1.82064
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980372
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8129
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00299
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912231
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07869
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836443
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88639
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.81615
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22234
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39676
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60969
C9orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15602
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02643
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.03426
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97812
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1778
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5516
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909175
Prostate adenocarcinoma_PRAD_TCGA-FC-A4JI-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28146
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59689
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72477
THP1	DepMap CRISPR Gene Dependency	1.0	3.34066
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4008
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30227
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31651
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
indicating	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04348
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37257
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46869
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12815
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71296
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44576
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
GSE198165,GSE198166_0_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67023
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11446_KD_TMEFF2_SRP302699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.54
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20265
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91072
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54102
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68335
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37018
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85832
HS819T	CCLE Cell Line Gene Expression Profiles	1.0	1.82606
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886285
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996637
kidney	HPA Tissue Gene Expression Profiles	1.0	0.882118
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75679
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841942
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865887
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SARS-CoV_72Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.57033
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.08907
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4506
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928239
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58315
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9441
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01406
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03285
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94193
HS742T	CCLE Cell Line Gene Expression Profiles	1.0	2.44364
Perturb_9102_KD_KDM3A_SRP202026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33707
PCDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10759
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30711
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.75783
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46296
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61466
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75007
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL29	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95433
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.92153
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48475
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987209
GSE152637_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30318
RVH421SKINFV1	DepMap CRISPR Gene Dependency	1.0	2.1603
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885864
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841629
hsa-miR-144	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5346
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09419
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895275
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40043
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05967
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.75835
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48375
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314772
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920365
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07175
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8182
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058184
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03538
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831823
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3468
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994239
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065084
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45018
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04993
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.908048
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28251
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.88618
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	2.97494
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15891
GSE233679_12_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.49659
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36672
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237216
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40047
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0287
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17006
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
Perturb_201_OE_Mir204_SRP131517	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.4949
IMPDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45435
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
Sarcoma_SARC_TCGA-DX-A1L0-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_2_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1543
GDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65377
Lung squamous cell carcinoma_LUSC_TCGA-85-7710-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20662
Brain Lower Grade Glioma_LGG_TCGA-HT-7676-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09662
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.99132
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78836
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963629
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LM4_M2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58914
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24291
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26178
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091033
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65G-01A-21R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73129
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0255
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80178
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80302
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873605
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86404
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04494
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17006
SARS-CoV_96Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.29655
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17572
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892756
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053335
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.2046
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71527
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83538
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90643
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
EIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80291
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18797
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.632
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5593
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959505
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980608
Perturb_1140_KO_Themis2_ERP005595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1728
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99497
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875992
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61103
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01459
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92416
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30015
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23643
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73695
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3058
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90004
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9478
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98208
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19551
GSE89018_1_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF862	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.118
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90845
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18333
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
Perturb_11195_KO_Pparg_SRP294559	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.97249
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40424
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47626
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2226
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02482
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214017
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53352
A2780	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79219
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15237
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0127
CHCHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32838
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24004
HS834T	CCLE Cell Line Gene Expression Profiles	1.0	1.77027
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880202
GPR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22346
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840352
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61177
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54828
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12659
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9468
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19267
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8499
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859868
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05659
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97387
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9799
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56384
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.08995
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987279
KBTBD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60327
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57956
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62171
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84487
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27614
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904675
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15231
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98689
CBX8	ENCODE Transcription Factor Targets	1.0	null
Perturb_15395_KD_RB1_SRP271262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45685
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63203
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98105
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	2.22709
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949715
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	3.04577
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850539
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94527
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4603
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05085
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924865
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96271
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07334
SW948	DepMap CRISPR Gene Dependency	1.0	9.56875
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.81317
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58059
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.956413
Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3794
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41242
SARS-dORF6_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.924696
PMC4777381-pone.0150624.s006.xlsx-dif_exp_AD-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.63894
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.699
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34007
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28509
5637	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76054
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6201
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885864
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100614_PCx_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32291
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880094
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28124
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.980361
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.975247
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90289
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17574
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909116
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99255
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03096
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c32	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3052
BFTC909	CCLE Cell Line Gene Expression Profiles	1.0	1.57085
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01242
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27088
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9766
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48134
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.5756
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963694
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01719
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
bj	HPA Cell Line Gene Expression Profiles	1.0	1.0409
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGFBR2_knockout_296_GSE22989	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.5168
Saphenous vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
peyer's gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764054
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.48587
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931264
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17459
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.507
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	2.47524
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.16483
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06263
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5812
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36309
PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866111
SUDHL8	DepMap CRISPR Gene Dependency	1.0	7.50298
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71547
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29444
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6636
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98357
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05707
ESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64955
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01534
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25125
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40371
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039333
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BFTC909	DepMap CRISPR Gene Dependency	1.0	2.91395
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5888
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21335
JAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61152
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29236
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.841942
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16754
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72963
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.76328
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831832
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0174
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2735
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67042
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852268
ac88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64018
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836872
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832297
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84243
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.888687
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52024
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992196
a549	HPA Cell Line Gene Expression Profiles	-1.0	-1.05292
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36112
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03538
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
Perturb_16891_KO_Lrrk2_SRP308389	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16847
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6349
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7134
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72166
Lung adenocarcinoma_LUAD_TCGA-55-7227-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
ntera2	HPA Cell Line Gene Expression Profiles	-1.0	-2.39705
LRRC4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19367
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6632
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82667
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04314
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13312
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.912054
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11765
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54264
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2849
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73A-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202175_1_v_2_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91677
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0696
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.978319
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7023
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41346
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34837
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31684
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962483
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0619
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78674
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09119
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875242
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893726
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1826
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19289
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94004
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.1822
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.975653
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.9488
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4719
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00096
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_TCF7L2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.871263
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
HL60	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35259
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28522
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55404
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62618
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1572
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5395
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.96103
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.02806
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947647
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16983
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3759
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81921
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12639
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38641
HSD17B4_KO_GDS3468_503_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20115
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34516
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38889
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01224
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMGI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61645
14737219-CSRgenes	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835913
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64273
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1833
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1287
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954282
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25222
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50385
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08645
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
CARHSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15493
FBXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4544
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222224
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20534
Perturb_4426_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51054
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893304
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29757
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21987
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.135
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67392
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0543
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43939
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27087
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93483
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00378
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38512
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18281
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977379
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.43746
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.125
TEAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2964
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.29081
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
igg immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.389682
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989143
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12045
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5605
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69418
HEK-293ET cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14231
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56548
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.1577
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14202
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25933
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908497
Perturb_11726_KO_Ikka_SRP229998	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DN-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.891705
Prostate adenocarcinoma_PRAD_TCGA-G9-6377-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCI-H441 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01086
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FL-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18223
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39921
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64661
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas	HPA Tissue Protein Expression Profiles	1.0	0.781809
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11362_KD_METTL3_SRP292229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.32612
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80721
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.61092
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.54273
RAP1GAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37367
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16085
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.952
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.62884
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27509
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PF382	CCLE Cell Line Gene Expression Profiles	1.0	1.41184
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05261
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
APOE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82522
ELL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40135
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58434
Kidney Chromophobe_KICH_TCGA-KO-8416-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03633
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
PMC11373733-ABR-13-34_Suppl1.pdf-278-TIGD1_TIGD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1703 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39426
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50573
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79075
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19289
GSE144796_1_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860058
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39081
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995258
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42201
k562	HPA Cell Line Gene Expression Profiles	-1.0	-1.1548
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4253
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0652
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13785
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97595
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.05941
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98086
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039232
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90835
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4033
Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12211
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53795
igainducing	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04744
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
ZDHHC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.813
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.007614
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885548
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851222
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67985
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885864
spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.346298
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60894
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MMAC	DepMap CRISPR Gene Dependency	1.0	4.76917
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1461
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11638
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19099
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055309
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.59012
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4762-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72931
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07256
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28926
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13395
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80292
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71976
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89699
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849139
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
ARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73508
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07178
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.986849
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29843
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888947
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29707
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.60547
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26821
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81153
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03418
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968269
ZNF732	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10379
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20191
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890043
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859931
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06263
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908721
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16141321-Table2	GeneSigDB Published Gene Signatures	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HS822T	CCLE Cell Line Gene Expression Profiles	1.0	1.38444
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	1.95927
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.897092
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9055
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97103
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_4_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30854
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
IRF1	ENCODE Transcription Factor Targets	1.0	null
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.57158
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7456
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10434
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937851
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838568
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2462
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.992
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02314
OV56	CCLE Cell Line Gene Expression Profiles	1.0	1.72971
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
MLYCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8092
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053501
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05011
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48372
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86837
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27991
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19688
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41359
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78144
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29922
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54842
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32719
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61813
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052361
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70566
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999093
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62414
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99473
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39034
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
NCIH226	DepMap CRISPR Gene Dependency	1.0	5.69676
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.58942
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57548
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25272
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00937
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02825
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35106
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.62945
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90379
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00614
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36192
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7743
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03567
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49587
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18238
hsa-miR-4774-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15273
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
CCDC87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6947
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965712
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057506
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06938
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03996
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5185
PMC3371315-NIHMS350140-supplement-13.xls-MCF7-T47D-SK-453_Up_Common_xls-Supplementary_Table_6_Luminal_Signature_Genes_increased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.3708
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894346
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6221
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03051
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04716
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28554
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42674
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22737
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21334
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92378
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07125
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.316
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Apical recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24435
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12141_KO_Lgals9_ERP122370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.03103
TASK1	DepMap CRISPR Gene Dependency	1.0	4.29475
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01453
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.737
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29082
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01454
GSE161055,GSE161056_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82985
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36412
GSE172490_5_v_3_junb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61914
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966718
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55551
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89307
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.85747
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
Proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161295_0_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71648
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42513
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38788
ZGLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02258
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180951_6_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01776
GATA5_KO_GDS4809_170_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46U-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35222
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898777
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0545
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94046
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5219
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04907
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.31
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11417
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41316
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.973947
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07845
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
f89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.221
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17171
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926729
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933558
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90172
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864369
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974439
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87815
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0434
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
NKX3-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25469
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33962
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92937
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054712
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04461
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851834
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50573
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973847
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907413
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6682
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30001
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.929422
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77677
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	7.48782
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31427
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.053
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02276
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37098
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84881
Saphenous vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61871
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98298
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82989
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56423
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864124
GSE233679_12_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40139
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39116
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67789
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886065
mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7722
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
Perturb_16632_Mut_Tardbp_SRP133158	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.95444
HS940T	CCLE Cell Line Gene Expression Profiles	1.0	1.50951
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04768
GSE179002_2_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0173
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15237
Perturb_17814_KO_Pdgfra_SRP051537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.15035
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.80134
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19367
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.564
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Testicular germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.01606
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28775
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66388
Perturb_8731_KD_HERV_SRP343980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_3700_OE_Atoh1_SRP191555	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78839
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56338
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04792
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965294
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00984
SIX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98198
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939918
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991163
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16268
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13412
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81568
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9389
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02834
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35597
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52729
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61864
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.911003
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.376
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840671
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58093
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8205
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99229
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907876
19351829-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15163
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54743
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15484
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.66099
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27027
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34137
hsa-miR-129-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.95018
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0304
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_290_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.19539
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21377
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59995
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867003
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17707
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11741
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27181
PKNOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38498
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65747
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824585
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU387	DepMap CRISPR Gene Dependency	1.0	2.06497
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12654
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03792
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081045
ALDH16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82215
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878215
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.037
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42669
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07409
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852676
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27633
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94323
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880488
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.929451
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47665
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.61248
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58805
SYPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39887
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0372
HOMER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61323
HCE4	DepMap CRISPR Gene Dependency	1.0	3.11402
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	2.1122
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40399
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44659
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.50902
661W cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11643
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968101
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64219
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28968
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.997265
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10088
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	3.45146
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18536
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866342
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07369
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25915
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828506
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43913
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17442
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887035
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SARS-BatSRBD_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.71508
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40428
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46936
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06914
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21124
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29913
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29968
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31364
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08512
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.74546
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193774
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98238
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05133
Glucosidase II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
B2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41528
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940092
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10321
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.26751
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850947
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48724
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7872
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45262
PBK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22751
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10863
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936116
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830738
T3M4	DepMap CRISPR Gene Dependency	1.0	2.62224
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3158
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215992
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832371
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90906
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55364
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08253
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57612
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1777
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0209
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17984
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869388
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888448
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.6871
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96082
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970549
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06286
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17744
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18399
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44738
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78852
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
EDNRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1381
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	3.38893
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20294
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0085
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268482
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4995-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13016
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920404
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95119
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PLPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51489
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967412
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36731
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60014
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28787
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22353
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17272
ATF7IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19531
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82785
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
SW403	CCLE Cell Line Gene Expression Profiles	1.0	1.75522
SNU1077	DepMap CRISPR Gene Dependency	1.0	3.3082
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879338
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8511
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04364
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497266
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.709
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03057
Perturb_15070_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.4522
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28429
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47936
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03418
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06047
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06639
CHD1	ENCODE Transcription Factor Targets	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972712
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11727
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17456
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841825
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.61884
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53814
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907894
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08579
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35191
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941277
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35732
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2091
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
HS737T	CCLE Cell Line Gene Expression Profiles	1.0	1.78027
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901009
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WS-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617