association	dataset	threshold value	standardized value
MRK-NU-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18922
stroke	GeneRIF Biological Term Annotations	1.0	null
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.57165
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.563
gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.677915
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal	GeneRIF Biological Term Annotations	1.0	null
Vitiligo	DisGeNET Gene-Disease Associations	1.0	null
contribute	GeneRIF Biological Term Annotations	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pleiotropic	GeneRIF Biological Term Annotations	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.5455
PMC5751286__F2	PFOCR Pathway Figure Associations 2023	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
Interleukin-10, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.41777
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colony	GeneRIF Biological Term Annotations	1.0	null
Prostate-basal cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	6.88382
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
waisthip	GeneRIF Biological Term Annotations	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9519
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12763
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09106
SCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.58227
strongly	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.8607
atherosclerosis	GeneRIF Biological Term Annotations	1.0	null
PMC6556902__F2	PFOCR Pathway Figure Associations 2024	1.0	null
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41688
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06947
GATA3	ENCODE Transcription Factor Targets	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971702
Aortic Valve Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909846
20460173-ImmPortCytokines	GeneSigDB Published Gene Signatures	1.0	null
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59866
kidney	GeneRIF Biological Term Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028486
PMC5069771__F2	PFOCR Pathway Figure Associations 2024	1.0	null
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pathways	GeneRIF Biological Term Annotations	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inflammation	GeneRIF Biological Term Annotations	1.0	null
OVCAR8	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59193
positive regulation of multicellular organismal process	GO Biological Process Annotations 2023	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.860604
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966328
PMC7037253__F2	PFOCR Pathway Figure Associations 2024	1.0	null
TTT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
epidermis	GeneRIF Biological Term Annotations	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
Cell wall-bounded periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7384
interactions	GeneRIF Biological Term Annotations	1.0	null
Hepatitis B, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7408575__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911756
Interleukin-20 family signaling	Reactome Pathways 2024	1.0	null
Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytokine Signaling in Immune system	Reactome Pathways 2024	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
injury	GeneRIF Biological Term Annotations	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967736
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5053
ratio	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02841
endothelial	GeneRIF Biological Term Annotations	1.0	null
kinasenfkappab	GeneRIF Biological Term Annotations	1.0	null
cytokine receptor binding	GO Molecular Function Annotations 2015	1.0	null
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5563
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE122206_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2975
positive regulation of epidermal cell differentiation	GO Biological Process Annotations 2023	1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
senescent	GeneRIF Biological Term Annotations	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13093
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biomarker	GeneRIF Biological Term Annotations	1.0	null
TAL1_megakaryocyte_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2839-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH28	CCLE Cell Line Gene Expression Profiles	1.0	1.70919
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5598
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22788
positive regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.822
Degenerative Polyarthritis	DisGeNET Gene-Disease Associations	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.8472
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.95799
test	GeneRIF Biological Term Annotations	1.0	null
regulation of epidermal cell differentiation	GO Biological Process Annotations 2023	1.0	null
different	GeneRIF Biological Term Annotations	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.36155
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
haplotype	GeneRIF Biological Term Annotations	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
il24	GeneRIF Biological Term Annotations	1.0	null
positive regulation of signaling receptor activity	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	3.40735
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66973
major depressive disorder	GAD Gene-Disease Associations	1.0	null
dna	GeneRIF Biological Term Annotations	1.0	null
ligand	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCA1_Knock-in_GDS3544_561_mouse_Cerebellum - 4 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6401-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lead	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87784
group	GeneRIF Biological Term Annotations	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
asthma	GeneRIF Biological Term Annotations	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0691
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal	GeneRIF Biological Term Annotations	1.0	null
Wheezing	DisGeNET Gene-Phenotype Associations	1.0	null
positive regulation of epithelial cell differentiation	GO Biological Process Annotations 2023	1.0	null
eNoSc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.115
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ligandreceptor	GeneRIF Biological Term Annotations	1.0	null
diabetes, type 1	GAD Gene-Disease Associations	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3619
therapeutic	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839418
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981941
SCABER	CCLE Cell Line Gene Expression Profiles	1.0	1.58701
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37165
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
specificity	GeneRIF Biological Term Annotations	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6919
Interleukin-20	InterPro Predicted Protein Domain Annotations	1.0	null
il10	GeneRIF Biological Term Annotations	1.0	null
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
Non-Alcoholic Fatty Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
variants	GeneRIF Biological Term Annotations	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	3.43815
unit	GeneRIF Biological Term Annotations	1.0	null
kinase	GeneRIF Biological Term Annotations	1.0	null
PMC6522222-NIHMS977514-supplement-Sup_Table_15.xlsx-WT3_WT5-Unnamed_0_POU6F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
correlated	GeneRIF Biological Term Annotations	1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
GATA3_01_163	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62885
hsa-miR-548o	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
infection	GeneRIF Biological Term Annotations	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative	GeneRIF Biological Term Annotations	1.0	null
synergetic	GeneRIF Biological Term Annotations	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3988
Disk, Herniated	DisGeNET Gene-Disease Associations	1.0	null
immune system process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1622
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4533
interleukin10	GeneRIF Biological Term Annotations	1.0	null
L33	DepMap CRISPR Gene Dependency	1.0	4.17922
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.40217
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibition	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reviewed	GeneRIF Biological Term Annotations	1.0	null
Airway Disease	DisGeNET Gene-Disease Associations	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17299
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
detected	GeneRIF Biological Term Annotations	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48537
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03925
biological regulation	GO Biological Process Annotations 2015	1.0	null
Colitis, Ulcerative	HuGE Navigator Gene-Phenotype Associations	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8666469__F3	PFOCR Pathway Figure Associations 2024	1.0	null
agents	GeneRIF Biological Term Annotations	1.0	null
diseases	GeneRIF Biological Term Annotations	1.0	null
simultaneous	GeneRIF Biological Term Annotations	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
mycophenolate mofetil_homo sapiens_gpl4133_gse45485	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18794137-SuppTable1d	GeneSigDB Published Gene Signatures	1.0	null
region	GeneRIF Biological Term Annotations	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF7_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BACH1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT1197	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92152
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6556902__F2	PFOCR Pathway Figure Associations 2023	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904124
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52408
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.601005
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-12340R (CDC2)	NURSA Protein Complexes	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
regulation of leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.730102
hsa-miR-568	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Brain Lower Grade Glioma_LGG_TCGA-R8-A6ML-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soluble	GeneRIF Biological Term Annotations	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24773
regulation of defense response	GO Biological Process Annotations 2015	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
jak stat signaling pathway	KEGG Pathways	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19317
population	GeneRIF Biological Term Annotations	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	3.18959
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.67462
identical	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-15a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
macrophages	GeneRIF Biological Term Annotations	1.0	null
defense response	GO Biological Process Annotations 2015	1.0	null
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
Kidney Failure, Acute	DisGeNET Gene-Disease Associations	1.0	null
contributes	GeneRIF Biological Term Annotations	1.0	null
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	5.63355
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.08592
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.926778
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.84687
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8614-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p40	GeneRIF Biological Term Annotations	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tolllike	GeneRIF Biological Term Annotations	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
il20il20r1il20r2	GeneRIF Biological Term Annotations	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3837
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.833328
effector	GeneRIF Biological Term Annotations	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
women	GeneRIF Biological Term Annotations	1.0	null
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01694
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
classical	GeneRIF Biological Term Annotations	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37554
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31991
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1944	DepMap CRISPR Gene Dependency	1.0	2.13461
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1687
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85674
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.45908
lesser	GeneRIF Biological Term Annotations	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12037
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47029
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
TBP	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51632
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B3-01A-12R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49896
MFE296	DepMap CRISPR Gene Dependency	1.0	2.6692
Colon ascendens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00888
Hernia	DisGeNET Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02272
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
il19	GeneRIF Biological Term Annotations	1.0	null
il28a	GeneRIF Biological Term Annotations	1.0	null
Viral protein interaction with cytokine and cytokine receptor	KEGG Pathways 2026	1.0	null
il6	GeneRIF Biological Term Annotations	1.0	null
PMC12783836-41398_2025_3738_MOESM3_ESM.xlsx-Table_S2-Table_S2_Causalities_in_the_forward_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.333
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAFK	ENCODE Transcription Factor Targets	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.801182
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
approximately	GeneRIF Biological Term Annotations	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02081
receptor binding	GO Molecular Function Annotations 2015	1.0	null
upper	GeneRIF Biological Term Annotations	1.0	null
Psoriasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
released	GeneRIF Biological Term Annotations	1.0	null
CAL27	CCLE Cell Line Gene Expression Profiles	1.0	1.65085
regulation of response to external stimulus	GO Biological Process Annotations 2025	1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20536
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11961
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973811
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
granulocytemacrophage	GeneRIF Biological Term Annotations	1.0	null
immune	GeneRIF Biological Term Annotations	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6833
brain	GeneRIF Biological Term Annotations	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3045
MM1S	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.62666
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.34987
essentially	GeneRIF Biological Term Annotations	1.0	null
regulation of tyrosine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14798
FOXP2	ENCODE Transcription Factor Targets	1.0	null
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
positive regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC4259415-oncotarget-05-10198-s002.xlsx-Sheet1-STAT3_Pathway_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3003
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32	DepMap CRISPR Gene Dependency	1.0	2.72046
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27188
Epithelial Hyperplasia Of Skin	DisGeNET Gene-Disease Associations	1.0	null
U178	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.04394
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA1	CCLE Cell Line Gene Expression Profiles	1.0	2.37247
PMC3382223__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55388
family	GeneRIF Biological Term Annotations	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
PMC7808269__F5	PFOCR Pathway Figure Associations 2024	1.0	null
control	GeneRIF Biological Term Annotations	1.0	null
three	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
Cell plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
modifications	GeneRIF Biological Term Annotations	1.0	null
higher	GeneRIF Biological Term Annotations	1.0	null
IL20RB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
jak1statactivating	GeneRIF Biological Term Annotations	1.0	null
modulating	GeneRIF Biological Term Annotations	1.0	null
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	1.1002
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7332
il20il24	GeneRIF Biological Term Annotations	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	0.833328
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38972
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory Sounds	HuGE Navigator Gene-Phenotype Associations	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.74609
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8256365-JCMM-25-6373-s003.xlsx-ONECUT1_KEGG_JAK_STAT_SIGNALING-PROBE_ONECUT1	Rummagene Transcription Factor Associations 2026	1.0	null
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	1.51489
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.66604
acute	GeneRIF Biological Term Annotations	1.0	null
Autoimmune disease of cardiovascular system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.938
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LTF	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE104604_1_v_0_eif5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4463	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
severity	GeneRIF Biological Term Annotations	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44503
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845789
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
caaac	GeneRIF Biological Term Annotations	1.0	null
Salivary_Gland-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	1.64789
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47983
PMC4389010__F1	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65041
showed	GeneRIF Biological Term Annotations	1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
han	GeneRIF Biological Term Annotations	1.0	null
constitute	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF172	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02526
YY1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-195	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.2029
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941993
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08706
interleukin	GeneRIF Biological Term Annotations	1.0	null
Hepatitis C	DisGeNET Gene-Disease Associations	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vitiligo-Associated Multiple Autoimmune Disease	DisGeNET Gene-Disease Associations	1.0	null
triggered	GeneRIF Biological Term Annotations	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
erythroid	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
stable	GeneRIF Biological Term Annotations	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.70338
nuclear	GeneRIF Biological Term Annotations	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.52555
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	2.04911
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Persistent Oligoarticular Juvenile Idiopathic Arthritis	DisGeNET Gene-Disease Associations	1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cutaneous	GeneRIF Biological Term Annotations	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
PMC7408575__F2	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02081
SKOV3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.93
chr1_206842880_A_G_b38	GTEx eQTL 2025	1.0	1.78296
myoepithelial	GeneRIF Biological Term Annotations	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08823
HCC1500	CCLE Cell Line Gene Expression Profiles	1.0	2.02585
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chinese	GeneRIF Biological Term Annotations	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-497	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87836
PMC6861325__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
correlations	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7569567__F2	PFOCR Pathway Figure Associations 2023	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57735
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ischemic	GeneRIF Biological Term Annotations	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6398
NR2F2_01_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59236
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.2259
tract	GeneRIF Biological Term Annotations	1.0	null
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
positive regulation of myeloid cell differentiation	GO Biological Process Annotations 2015	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844602
subfamily	GeneRIF Biological Term Annotations	1.0	null
HT29	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1083
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOMO1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11621
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
positive regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.253
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
possibly	GeneRIF Biological Term Annotations	1.0	null
E2F3_KD_GDS4094_448_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ulcerative	GeneRIF Biological Term Annotations	1.0	null
PMC9374760__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
inflammatory response	GO Biological Process Annotations 2015	1.0	null
il5	GeneRIF Biological Term Annotations	1.0	null
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6556902__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of tyrosine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
immune response	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.57771
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12783836-41398_2025_3738_MOESM3_ESM.xlsx-Table_S5-Table_S5_Pleiotropy_assessment_for_the_significant_results_of_forward_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IST-MES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
infection	GAD High Level Gene-Disease Associations	1.0	0.305726
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
RKN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35116
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.30846
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
matched	GeneRIF Biological Term Annotations	1.0	null
EP300_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
PMC7808269__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
transcriptional	GeneRIF Biological Term Annotations	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.54891
autocrineparacrine	GeneRIF Biological Term Annotations	1.0	null
20458058-TableS3b	GeneSigDB Published Gene Signatures	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.938
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02688
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple Sclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-499-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Kidney Injury	DisGeNET Gene-Disease Associations	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57701
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4689
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.42315
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	2.79298
tissue	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.300114
predictors	GeneRIF Biological Term Annotations	1.0	null
positive regulation of epidermis development	GO Biological Process Annotations 2023	1.0	null
cytokine receptor binding	GO Molecular Function Annotations 2023	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
Respiratory Tract Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4651
hsa-miR-624	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
lesional	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23617
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63337
positive regulation of leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1_erythroblast_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90891
positive regulation of tyrosine phosphorylation of stat3 protein	GO Biological Process Annotations 2015	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.67462
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
extended	GeneRIF Biological Term Annotations	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851312
PMC5607433__F5	PFOCR Pathway Figure Associations 2023	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877097
TE10	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.48175
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13487
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
light	GeneRIF Biological Term Annotations	1.0	null
significant	GeneRIF Biological Term Annotations	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21324
regulation of multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
megakaryocyte	GeneRIF Biological Term Annotations	1.0	null
keratinocyte	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3674	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	DepMap CRISPR Gene Dependency	1.0	4.648
Oral Ulcer	DisGeNET Gene-Disease Associations	1.0	null
combined	GeneRIF Biological Term Annotations	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
positive regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3449
PLB985	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30997
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of myeloid leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66977
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNAi_-666_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mononuclear	GeneRIF Biological Term Annotations	1.0	null
outcome	GeneRIF Biological Term Annotations	1.0	null
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
KYSE150	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49362
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31333
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18241
types	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCT15	DepMap CRISPR Gene Dependency	1.0	3.72752
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of inflammatory response	GO Biological Process Annotations 2023	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.67462
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
il21	GeneRIF Biological Term Annotations	1.0	null
genotypes	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNUC4	DepMap CRISPR Gene Dependency	1.0	2.6423
BECKER	DepMap CRISPR Gene Dependency	1.0	5.93034
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brittle Diabetes	DisGeNET Gene-Disease Associations	1.0	null
allele	GeneRIF Biological Term Annotations	1.0	null
Hidradenitis Suppurativa	DisGeNET Gene-Disease Associations	1.0	null
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62751
migration	GeneRIF Biological Term Annotations	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1917
COLO704	CCLE Cell Line Gene CNV Profiles	1.0	1.37293
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941993
regulation of myeloid leukocyte differentiation	GO Biological Process Annotations 2015	1.0	null
positive regulation of keratinocyte differentiation	GO Biological Process Annotations 2023	1.0	null
transplanted	GeneRIF Biological Term Annotations	1.0	null
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7375
MEK_INHIBITION_GDS5029_279_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IL20RA	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
il20	GeneRIF Biological Term Annotations	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular region	GO Cellular Component Annotations 2015	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	2.88009
regulation of tyrosine phosphorylation of stat3 protein	GO Biological Process Annotations 2015	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
psoriasis	GeneRIF Biological Term Annotations	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3199	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
suppressed	GeneRIF Biological Term Annotations	1.0	null
PMC6537282__F1	PFOCR Pathway Figure Associations 2023	1.0	null
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	9.26649
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.71005
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44532
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-20 receptor binding	GO Molecular Function Annotations 2025	1.0	null
regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1099
PMC12419315-medi-104-e44180-s001.xlsx-Table_S4-MR_estimates_of_PCa_on_ninety-one_inflammatory_cytokines_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of tyrosine phosphorylation of STAT protein	GO Biological Process Annotations 2023	1.0	null
HCC2935	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69535
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.36256
vitro	GeneRIF Biological Term Annotations	1.0	null
PMC6487024-13148_2019_658_MOESM2_ESM.xlsx-S10-Pr_intrc_ADNP-1-Unnamed_1_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
interleukin-10 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.766
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
pathophysiologic	GeneRIF Biological Term Annotations	1.0	null
ESR1_T47D_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colitis	GeneRIF Biological Term Annotations	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytokine cytokine receptor interaction	KEGG Pathways	1.0	null
BICR18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60689
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE209928_0_v_1_kmt2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
increased circulating alanine transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	2.41296
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
il29	GeneRIF Biological Term Annotations	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.83731
modulator	GeneRIF Biological Term Annotations	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.69
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6197
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.833328
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33253
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12042
ZR751	CCLE Cell Line Gene Expression Profiles	1.0	1.87134
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.97639
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909846
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81461
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8008
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transgenic	GeneRIF Biological Term Annotations	1.0	null
based	GeneRIF Biological Term Annotations	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970243
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.53527
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
KLE	DepMap CRISPR Gene Dependency	1.0	2.10072
multipotential	GeneRIF Biological Term Annotations	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40373
Bone Destruction	DisGeNET Gene-Disease Associations	1.0	null
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3409-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
residue	GeneRIF Biological Term Annotations	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7583966__F3	PFOCR Pathway Figure Associations 2023	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1643
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
quantification	GeneRIF Biological Term Annotations	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6218-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979964
PMC4647707__F4	PFOCR Pathway Figure Associations 2023	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-W9-A837-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory	GeneRIF Biological Term Annotations	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5611503__F9	PFOCR Pathway Figure Associations 2023	1.0	null
regulation of tyrosine phosphorylation of STAT protein	GO Biological Process Annotations 2025	1.0	null
abnormal type IV hypersensitivity reaction	MGI Mouse Phenotype Associations 2023	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52507
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0653
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-02A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of response to external stimulus	GO Biological Process Annotations 2023	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.04868
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antagonist	GeneRIF Biological Term Annotations	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH508	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48233
obese	GeneRIF Biological Term Annotations	1.0	null
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	1.99057
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inducing	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06886
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synthesized	GeneRIF Biological Term Annotations	1.0	null
effects	GeneRIF Biological Term Annotations	1.0	null
snps	GeneRIF Biological Term Annotations	1.0	null
regulation of response to stress	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7470101__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.605
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.45018
SCC25	CCLE Cell Line Gene Expression Profiles	1.0	1.86172
positive regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2023	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32755
Vesico-Ureteral Reflux	DisGeNET Gene-Disease Associations	1.0	null
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0294
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3132
HDAC6	ENCODE Transcription Factor Targets	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
european	GeneRIF Biological Term Annotations	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6809
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1339
PMC4266326__F2a	PFOCR Pathway Figure Associations 2023	1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
GSE237984_1_v_2_magi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851312
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4II-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
solvent	GeneRIF Biological Term Annotations	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847969
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1885
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5869528__F10	PFOCR Pathway Figure Associations 2023	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAK2_druginhibition_168_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49488
epigenetically	GeneRIF Biological Term Annotations	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.996875
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9159
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reflux	GeneRIF Biological Term Annotations	1.0	null
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.57619
OVCAR8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.88597
PMC6298946__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14705
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_mus musculus_gpl7509_gse14774	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
il20tg	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18016
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08299
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33089
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04432
KMS20	DepMap CRISPR Gene Dependency	1.0	3.92722
regulation of epidermal cell differentiation	GO Biological Process Annotations 2025	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847969
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
De Quervain Disease	DisGeNET Gene-Disease Associations	1.0	null
Four-helical cytokine-like, core	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.83965
positive regulation of epidermis development	GO Biological Process Annotations 2015	1.0	null
influence	GeneRIF Biological Term Annotations	1.0	null
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971702
mapk	GeneRIF Biological Term Annotations	1.0	null
sclerosis	GeneRIF Biological Term Annotations	1.0	null
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60347
PMC12695664-41588_2025_2410_MOESM4_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.924121
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
little	GeneRIF Biological Term Annotations	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06886
il20expressing	GeneRIF Biological Term Annotations	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9597993__F2	PFOCR Pathway Figure Associations 2024	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	5.13174
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887666
serum	GeneRIF Biological Term Annotations	1.0	null
Lupus Nephritis	DisGeNET Gene-Disease Associations	1.0	null
PMC4647707__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC5742522-peerj-05-4214-s005.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
african	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48191
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1271
PAX5	ENCODE Transcription Factor Targets	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36716
Mercuric Chloride	CTD Gene-Chemical Interactions	1.0	null
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
posttranslational	GeneRIF Biological Term Annotations	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30644
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
models	GeneRIF Biological Term Annotations	1.0	null
ustekinumab	GeneRIF Biological Term Annotations	1.0	null
Diabetes Mellitus, Type 1	CTD Gene-Disease Associations	1.0	2.88009
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5869528__F10	PFOCR Pathway Figure Associations 2024	1.0	null
JAK-STAT signaling pathway	KEGG Pathways 2026	1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1246
positive regulation of epidermal cell differentiation	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
five	GeneRIF Biological Term Annotations	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.668011
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991246
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI4	ChEA Transcription Factor Targets	1.0	null
PMC6857915__F7	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.98272
regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44503
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969594
PMC11605493-EXD-33-e15152-s001.docx-1-FBXL19_FBXL19	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory Syncytial Virus Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
IGROV1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24588
positive regulation of jak-stat cascade	GO Biological Process Annotations 2015	1.0	null
redundant	GeneRIF Biological Term Annotations	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.46358
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17371
PMC5968398-Table_2.docx-1-IKZF3_IKZF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
PMC5611503__F9	PFOCR Pathway Figure Associations 2024	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
IGR39	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10845
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5481
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T0-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of jak-stat cascade	GO Biological Process Annotations 2015	1.0	null
PMC4822853__F3	PFOCR Pathway Figure Associations 2023	1.0	null
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
positive regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of osteoclast differentiation	GO Biological Process Annotations 2015	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9166
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18678
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-499a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851312
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0277
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle	GeneRIF Biological Term Annotations	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ppp	GeneRIF Biological Term Annotations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6556902__F3	PFOCR Pathway Figure Associations 2023	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0224
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
inflammatory	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28901
Chromatin silencing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
interleukin-20 receptor binding	GO Molecular Function Annotations 2023	1.0	null
papillary	GeneRIF Biological Term Annotations	1.0	null
PMC7470101__F1	PFOCR Pathway Figure Associations 2024	1.0	null
positive regulation of hemopoiesis	GO Biological Process Annotations 2015	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GP2D	Achilles Cell Line Gene Essentiality Profiles	1.0	2.56962
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.49428
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0227
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6833
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91418
Psoriatic Conditions	DisGeNET Gene-Disease Associations	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.035
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	2.11549
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10808687-Table_1.xlsx-Supplementary_Table_9-Supplementary_Table_9_Replication_MR_analysis_results_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9609
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-634	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
regulation of epidermal cell differentiation	GO Biological Process Annotations 2015	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.571756
769-P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mrsa - Methicillin Resistant Staphylococcus Aureus Infection	DisGeNET Gene-Disease Associations	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
binding	GO Molecular Function Annotations 2015	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
several	GeneRIF Biological Term Annotations	1.0	null
interleukin-20 receptor binding	GO Molecular Function Annotations 2015	1.0	null
MYC_01_324	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.04959
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14705
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of immune system process	GO Biological Process Annotations 2015	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UMUC11	DepMap CRISPR Gene Dependency	1.0	3.47385
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2523
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-1323	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868195
SNU324	CCLE Cell Line Gene CNV Profiles	1.0	1.44729
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0321
molecular_function	GO Molecular Function Annotations 2015	1.0	null
produced	GeneRIF Biological Term Annotations	1.0	null
18794102-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.13163
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10233
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
polymorphism	GeneRIF Biological Term Annotations	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967736
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6557
arthritis	GeneRIF Biological Term Annotations	1.0	null
Bronchiolitis, Viral	HuGE Navigator Gene-Phenotype Associations	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2828
PMC10808687-Table_1.xlsx-Supplementary_Table_4-Supplementary_Table_4_Discovery_of_positive_MR_analysis_results_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	2.31323
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-659	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50145
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of hemopoiesis	GO Biological Process Annotations 2015	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIAML5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59712
tnfalpha	GeneRIF Biological Term Annotations	1.0	null
revealed	GeneRIF Biological Term Annotations	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9269
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibits	GeneRIF Biological Term Annotations	1.0	null
20460173-ImmPortInterleukins	GeneSigDB Published Gene Signatures	1.0	null
positive regulation of epidermal cell differentiation	GO Biological Process Annotations 2025	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17999
hypoxia	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824422
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
elevated	GeneRIF Biological Term Annotations	1.0	null
indicator	GeneRIF Biological Term Annotations	1.0	null
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64876
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
content	GeneRIF Biological Term Annotations	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0842
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transduction	GeneRIF Biological Term Annotations	1.0	null
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L33	CCLE Cell Line Gene Expression Profiles	1.0	1.67222
cytokine	GeneRIF Biological Term Annotations	1.0	null
Overview of proinflammatory and profibrotic mediators	WikiPathways Pathways 2024	1.0	null
nonneoplastic	GeneRIF Biological Term Annotations	1.0	null
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1128
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronic Multifocal Osteomyelitis	DisGeNET Gene-Disease Associations	1.0	null
19802007-Table2	GeneSigDB Published Gene Signatures	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24062
SNU1033	DepMap CRISPR Gene Dependency	1.0	5.75794
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
positive regulation of keratinocyte differentiation	GO Biological Process Annotations 2025	1.0	null
PMC4792926-ncomms10810-s3.xlsx-list_2_PHF20-dependent_E2_genes-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Four-helical cytokine, core	InterPro Predicted Protein Domain Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971702
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67441
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
distribution	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT1197	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.8239
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5552
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17623
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBR2_knockout_295_GSE45968	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52671
regulation of inflammatory response	GO Biological Process Annotations 2015	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98258
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8009
leading	GeneRIF Biological Term Annotations	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
EFM-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
contains	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-876-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
weight	GeneRIF Biological Term Annotations	1.0	null
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20949
Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5370073__F1	PFOCR Pathway Figure Associations 2024	1.0	null
A204	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.50714
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
enhanced	GeneRIF Biological Term Annotations	1.0	null
JAK1_druginhibition_166_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49488
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
PMC5069771__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8504
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
while	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6775-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pustulosis Of Palms And Soles	DisGeNET Gene-Disease Associations	1.0	null
PMC7036277-peerj-08-8662-s005.xlsx-42_genes_were_downregulated_in-Supplemental_Table_S3_42_genes_were_downregulated_in_the_EN2-Eca109_cells_as_compared_with_the_NEO-Eca109_cells_Related_to_Figure_5A_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6274312__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3701
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	2.18865
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
formation	GeneRIF Biological Term Annotations	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of myeloid cell differentiation	GO Biological Process Annotations 2015	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
cellular	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	CCLE Cell Line Gene Expression Profiles	1.0	1.36861
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4822853__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.70736
POR_KO_GDS1678_761_mouse_ILEUM	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LN229	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03178
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kappab	GeneRIF Biological Term Annotations	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forms	GeneRIF Biological Term Annotations	1.0	null
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75591
PMC3609811__F2	PFOCR Pathway Figure Associations 2024	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRHL3_01_336	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64548
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18472
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07067
hsa-miR-424	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-576-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8148
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.037
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
differentiation	GeneRIF Biological Term Annotations	1.0	null
Aggressive Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
hepatitis	GeneRIF Biological Term Annotations	1.0	null
regulation of keratinocyte differentiation	GO Biological Process Annotations 2015	1.0	null
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13093
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910785
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5472
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytokine-cytokine receptor interaction	KEGG Pathways 2026	1.0	null
Behcet Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JHU011	DepMap CRISPR Gene Dependency	1.0	3.75914
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90014
biology	GeneRIF Biological Term Annotations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844602
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.60409
KYO1	DepMap CRISPR Gene Dependency	1.0	6.70564
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
receptors	GeneRIF Biological Term Annotations	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57782
SUPM2	CCLE Cell Line Gene CNV Profiles	1.0	2.71305
then	GeneRIF Biological Term Annotations	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	7.5614
hsa-miR-4524	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SUP-M2	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
pustulosis	GeneRIF Biological Term Annotations	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of tyrosine phosphorylation of STAT protein	GO Biological Process Annotations 2023	1.0	null
YBX1_01_64	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65576
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
signalregulated	GeneRIF Biological Term Annotations	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2485
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
proatherogenic	GeneRIF Biological Term Annotations	1.0	null
spondyloarthropathy	GeneRIF Biological Term Annotations	1.0	null
other	GAD High Level Gene-Disease Associations	1.0	0.293278
keratinocytes	GeneRIF Biological Term Annotations	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC1SQSF	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96118
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of keratinocyte differentiation	GO Biological Process Annotations 2015	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1978
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96205
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
resulted	GeneRIF Biological Term Annotations	1.0	null
regulation of defense response	GO Biological Process Annotations 2025	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24474
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02867
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.69197
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
il1	GeneRIF Biological Term Annotations	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.62703
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844602
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.53755
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extent	GeneRIF Biological Term Annotations	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970243
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-491-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.949073
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62258
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7090-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01177
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62694
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92922
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.64
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852275
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0688
asthma; bronchiolitis, viral; respiratory syncytial virus infections	GAD Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
asymmetric	GeneRIF Biological Term Annotations	1.0	null
within	GeneRIF Biological Term Annotations	1.0	null
p38	GeneRIF Biological Term Annotations	1.0	null
ultraviolet	GeneRIF Biological Term Annotations	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.88916
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH10TC	DepMap CRISPR Gene Dependency	1.0	4.75564
Acute Kidney Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	1.35224
CAS1	DepMap CRISPR Gene Dependency	1.0	3.70909
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9069
PMC3436816__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911756
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67D-01A-31R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAR/SIN/STRIPAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.321
examination	GeneRIF Biological Term Annotations	1.0	null
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hepatitis c	GAD Gene-Disease Associations	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2025	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
interleukin20	GeneRIF Biological Term Annotations	1.0	null
KIJK	CCLE Cell Line Gene CNV Profiles	1.0	1.36042
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3038
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
hsa-miR-561	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DLD1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.5935
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HSC4	DepMap CRISPR Gene Dependency	1.0	2.60793
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.986428
photosensitizing	GeneRIF Biological Term Annotations	1.0	null
Postlarva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
ART5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40507
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
Pre-Renal Acute Kidney Injury	DisGeNET Gene-Disease Associations	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.17399
Intraocular Pressure Disorder	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-15b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
systemic	GeneRIF Biological Term Annotations	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH322	DepMap CRISPR Gene Dependency	1.0	3.03573
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
SALL4	ChEA Transcription Factor Targets	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
mesangial	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17700529-Table2	GeneSigDB Published Gene Signatures	1.0	null
p21waf1	GeneRIF Biological Term Annotations	1.0	null
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.16919
Hepatitis C, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63697
positive regulation of epithelial cell differentiation	GO Biological Process Annotations 2015	1.0	null
PMC5742522-peerj-05-4214-s004.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_AND_strabismic_lateral_rectus_LR_vs_donor_LR_experiments_COMBINED_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-2.77891
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediators	GeneRIF Biological Term Annotations	1.0	null
Arthritis, Juvenile Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76958
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.886
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC4596691__F4	PFOCR Pathway Figure Associations 2023	1.0	null
17700529-Table1	GeneSigDB Published Gene Signatures	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08758
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4525
inhibitory	GeneRIF Biological Term Annotations	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5607433__F5	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.042822
disc	GeneRIF Biological Term Annotations	1.0	null
fibrosis	GeneRIF Biological Term Annotations	1.0	null
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
demonstrates	GeneRIF Biological Term Annotations	1.0	null
positive regulation of osteoclast differentiation	GO Biological Process Annotations 2015	1.0	null
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.938
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.707
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytokine activity	GO Molecular Function Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910785
PMC3022822-1471-2164-12-11-S5.XLS-Tabld_S4_GO-0045595geneset_txt-Additional_File_5_SOX2_binding_targets_in_GO_0045595_REGULATION_OF_CELL_DIFFERENTIATION_geneset_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-16	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9517
PMC4792926-ncomms10810-s3.xlsx-list3_G9a_PHF20-overlaps-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02491
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12752
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.19229
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2507
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00125
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4551
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19802007-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Spondylarthritis	DisGeNET Gene-Disease Associations	1.0	null
GSE241031_0_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
il19il20	GeneRIF Biological Term Annotations	1.0	null
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877483
PMC5370073__F1	PFOCR Pathway Figure Associations 2023	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67591
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1189
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	1.57947
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3229
cpg	GeneRIF Biological Term Annotations	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0265
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLETIKUMAB	DGIdb Drug Targets 2026	1.0	52.932
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77472
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6661
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911756
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09275
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
discrimination	GeneRIF Biological Term Annotations	1.0	null
regulation of keratinocyte differentiation	GO Biological Process Annotations 2023	1.0	null
Cutaneous leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
TC32	CCLE Cell Line Gene CNV Profiles	1.0	1.50081
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09884
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC3609811__F2	PFOCR Pathway Figure Associations 2023	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	6.22519
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.57213
analytes	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897081
PMC7100912-EMS85677-supplement-Suppl__Tables_1_8.xlsx-Table_6-Supplementary_Table_6_Nanostring_gene_expression_profiling_of_memory_T_cells_transduced_with_BHLHE40_BHLHE40	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1677
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
taken	GeneRIF Biological Term Annotations	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
crystallographic	GeneRIF Biological Term Annotations	1.0	null
Plasmodium vivax malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67383
Mucocutaneous leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8431
PMC3382223__F2	PFOCR Pathway Figure Associations 2024	1.0	null
FTC238	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51831
PMC6274312__F5	PFOCR Pathway Figure Associations 2024	1.0	null
gacaccggaa	GeneRIF Biological Term Annotations	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bladder	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF_01_79	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61179
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
phenotypes	GeneRIF Biological Term Annotations	1.0	null
th2	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3671	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80168
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9062
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	67.4289
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907739
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5094
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3382223__F3	PFOCR Pathway Figure Associations 2024	1.0	null
mexican	GeneRIF Biological Term Annotations	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.833328
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8043
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.710382
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
Sarcoma_SARC_TCGA-DX-A3UF-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146687_2_v_6_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52507
serve	GeneRIF Biological Term Annotations	1.0	null
PMC8388390__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4389010__F1	PFOCR Pathway Figure Associations 2023	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
associations	GeneRIF Biological Term Annotations	1.0	null
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186151_1_v_0_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.987
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.831861
positive regulation of epidermis development	GO Biological Process Annotations 2025	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.4293
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03831
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mmp9	GeneRIF Biological Term Annotations	1.0	null
premenopausal	GeneRIF Biological Term Annotations	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44407
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06886
DANG	DepMap CRISPR Gene Dependency	1.0	2.84284
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44416
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10452
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36578
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.41012
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835448
recombinant	GeneRIF Biological Term Annotations	1.0	null
regulation of defense response	GO Biological Process Annotations 2023	1.0	null
nephritis	GeneRIF Biological Term Annotations	1.0	null
regulation of response to wounding	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitogenactivated	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular ketone metabolic process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08915
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4821
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
exacerbated	GeneRIF Biological Term Annotations	1.0	null
PMC3382223__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	4.39409
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6861325__F4	PFOCR Pathway Figure Associations 2023	1.0	null
crucial	GeneRIF Biological Term Annotations	1.0	null
Vesicoureteral Reflux	DisGeNET Gene-Disease Associations	1.0	null
496100329_FWM_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.6452
Lung squamous cell carcinoma_LUSC_TCGA-21-1079-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upregulation	GeneRIF Biological Term Annotations	1.0	null
major	GeneRIF Biological Term Annotations	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0462
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Interleukin-10/19/20/24/26 family	InterPro Predicted Protein Domain Annotations	1.0	null
il17a	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of keratinocyte differentiation	GO Biological Process Annotations 2025	1.0	null
altogether	GeneRIF Biological Term Annotations	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08823
CHD2	ENCODE Transcription Factor Targets	1.0	null
Perturb_2595_KD_SMURF1_SRP115428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.11549
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
highly	GeneRIF Biological Term Annotations	1.0	null
Rectal prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6408
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.62173
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910785
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
had	GeneRIF Biological Term Annotations	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.955934
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4573
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of epidermis development	GO Biological Process Annotations 2015	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47934
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21818
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0237
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46903
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.34362
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.70538
palmoplantar	GeneRIF Biological Term Annotations	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0277
RAD21	ENCODE Transcription Factor Targets	1.0	null
hepatitis b, chronic	GAD Gene-Disease Associations	1.0	null
BT483	CCLE Cell Line Gene Expression Profiles	1.0	2.65493
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2015	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
responsive	GeneRIF Biological Term Annotations	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5416
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.592
hMPV_6Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6445
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0277
Brain Infarction	DisGeNET Gene-Disease Associations	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
progenitors	GeneRIF Biological Term Annotations	1.0	null
Eczema	DisGeNET Gene-Disease Associations	1.0	null
corresponding	GeneRIF Biological Term Annotations	1.0	null
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48859
positive regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02587
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00936
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8432
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06886
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cd40	GeneRIF Biological Term Annotations	1.0	null
separate	GeneRIF Biological Term Annotations	1.0	null
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37937
CTCF	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9303
Osteopenia	DisGeNET Gene-Disease Associations	1.0	null
supporting	GeneRIF Biological Term Annotations	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69006
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851312
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7179
PMC11328671-jitc-12-4-s003.pdf-151-IKZF4_IKZF4	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5035
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.49703
extracellular	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
il19gc	GeneRIF Biological Term Annotations	1.0	null
fluid	GeneRIF Biological Term Annotations	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rejection	GeneRIF Biological Term Annotations	1.0	null
regulation of cell differentiation	GO Biological Process Annotations 2015	1.0	null
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35147
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926599
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
methylation	GeneRIF Biological Term Annotations	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65641
represent	GeneRIF Biological Term Annotations	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18979
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
herniation	GeneRIF Biological Term Annotations	1.0	null
PMC1705513__F1	PFOCR Pathway Figure Associations 2023	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Pneumonitis	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
jak1stat	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	DisGeNET Gene-Phenotype Associations	1.0	null
hcv	GeneRIF Biological Term Annotations	1.0	null
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.926
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9415
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.45239
HEL	DepMap CRISPR Gene Dependency	1.0	3.52635
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
ligands	GeneRIF Biological Term Annotations	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17371
skeletal	GeneRIF Biological Term Annotations	1.0	null
cox2pge2	GeneRIF Biological Term Annotations	1.0	null
plasma	GeneRIF Biological Term Annotations	1.0	null
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44532
increased circulating alanine transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
PMC12419315-medi-104-e44180-s001.xlsx-Table_S1-MR_estimates_of_ninety-one_inflammatory_cytokines_on_PCa_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene Expression Profiles	1.0	1.46609
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of inflammatory response	GO Biological Process Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
haplotypes	GeneRIF Biological Term Annotations	1.0	null
erkmediated	GeneRIF Biological Term Annotations	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0192
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46336
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
PMC7037253__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XG-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.099
interleukin-22 receptor binding	GO Molecular Function Annotations 2015	1.0	null
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
PMC4596691__F4	PFOCR Pathway Figure Associations 2024	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.93777
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart  (day 12.5 C57Bl/6)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	4.36689
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cell differentiation	GO Biological Process Annotations 2015	1.0	null
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synovial	GeneRIF Biological Term Annotations	1.0	null
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3436816__F2	PFOCR Pathway Figure Associations 2023	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.033
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3472
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7684
PMC10873402__F5	PFOCR Pathway Figure Associations 2024	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74194
Respiratory Syncytial Virus (Rsv) Infection In Conditions Classified Elsewhere And Of Unspecified Site	DisGeNET Gene-Disease Associations	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ccl2mcp1	GeneRIF Biological Term Annotations	1.0	null
Asthma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Generalized Pustular Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Respiratory Syncytial Virus Bronchiolitis	DisGeNET Gene-Disease Associations	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30742
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_9_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytokines	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.938
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885168
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
positive regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A148-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930336
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06141
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41589
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ils	GeneRIF Biological Term Annotations	1.0	null
virus	GeneRIF Biological Term Annotations	1.0	null
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18678
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Failure	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of tyrosine phosphorylation of STAT protein	GO Biological Process Annotations 2025	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc6.xlsx-PIAS1_KD_down-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vegf	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-8468-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Unipolar Depression	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PJ-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.3388
11823860-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3927	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.96139
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
regulation of epithelial cell differentiation	GO Biological Process Annotations 2015	1.0	null
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
proliferation	GeneRIF Biological Term Annotations	1.0	null
PMC9086235__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.34263
BT483	CCLE Cell Line Gene CNV Profiles	1.0	1.44507
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.108
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytokine receptor binding	GO Molecular Function Annotations 2025	1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911756
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Behcet's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.938
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
observed	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879495
Lumbar Spondylolisthesis	DisGeNET Gene-Phenotype Associations	1.0	null
CRO-AP2	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cytolytic granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
PMC9372960__F1	PFOCR Pathway Figure Associations 2024	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.38258
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	0.929317
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27705
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0943
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	GeneRIF Biological Term Annotations	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.15931
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lupus	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
scleroderma	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.82264
promotes	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911756
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41688
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970243
loss	GeneRIF Biological Term Annotations	1.0	null
model	GeneRIF Biological Term Annotations	1.0	null
PMC4266326__F2a	PFOCR Pathway Figure Associations 2024	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	2.70417
NCIH1975	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67002
regulation of response to external stimulus	GO Biological Process Annotations 2015	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
NB13	DepMap CRISPR Gene Dependency	1.0	7.67382
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_16_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79988
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57576
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85683
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Tendinopathy	DisGeNET Gene-Disease Associations	1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
RVH421	DepMap CRISPR Gene Dependency	1.0	3.68175
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2024
angiogenesis	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7395311__F3	PFOCR Pathway Figure Associations 2023	1.0	null
extracellular space	GO Cellular Component Annotations 2015	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
decreased startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28427
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
baseline	GeneRIF Biological Term Annotations	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.83194
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3196
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
one	GeneRIF Biological Term Annotations	1.0	null
mouse	GeneRIF Biological Term Annotations	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reveals	GeneRIF Biological Term Annotations	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46722
members	GeneRIF Biological Term Annotations	1.0	null
natural	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signaling by Interleukins	Reactome Pathways 2024	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38035
KPL1	CCLE Cell Line Gene Expression Profiles	1.0	1.81812
EFM19	CCLE Cell Line Gene Expression Profiles	1.0	2.27603
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Cytokine cytokine receptor interaction	WikiPathways Pathways 2024	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2257
TAL1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hiv infections; [x]human immunodeficiency virus disease	GAD Gene-Disease Associations	1.0	null
PMC3607232-mmc3.xlsx-RUNX1_targets_in_K562_and_SEM-x_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79529
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.841862
presence	GeneRIF Biological Term Annotations	1.0	null
NCIN87	Achilles Cell Line Gene Essentiality Profiles	1.0	1.75296
particularly	GeneRIF Biological Term Annotations	1.0	null
Infant, Premature, Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
epithelial	GeneRIF Biological Term Annotations	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7721
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
il22	GeneRIF Biological Term Annotations	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of epithelial cell differentiation	GO Biological Process Annotations 2025	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0075
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vesicoureteral	GeneRIF Biological Term Annotations	1.0	null
cytokine activity	GO Molecular Function Annotations 2025	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.08314
histone	GeneRIF Biological Term Annotations	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	4.08786
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18352
rheumatoid	GeneRIF Biological Term Annotations	1.0	null
cd34	GeneRIF Biological Term Annotations	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.67462
americans	GeneRIF Biological Term Annotations	1.0	null
body	GeneRIF Biological Term Annotations	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
nfkappab	GeneRIF Biological Term Annotations	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clearance	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null