association	dataset	threshold value	standardized value
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50525
TASK1	DepMap CRISPR Gene Dependency	1.0	10.887
BRD-K31110422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26682
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
attributes	GeneRIF Biological Term Annotations	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gallbladder Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_7766_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4286
BC-13-OQ01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.352312
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867745
menadione-2439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
metastatic	GeneRIF Biological Term Annotations	1.0	null
BRD-K16789950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53935
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31518
CLK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517159
fluphenazine-2697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-ensembl_gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.624645
PMC7902901-Table_12.xlsx-JUN-Unnamed_7_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15809
clebopride-1292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chlorpromazine-1822	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Generalized Pustular Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
azacyclonol-5398	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45296
bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561245
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042318
Hyperlipidemias	CTD Gene-Disease Associations	1.0	1.11081
Premature Birth	CTD Gene-Disease Associations	1.0	1.25899
Typhoid Fever	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899059
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03931
BRD-K53900606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06106
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04044
distribution	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65269
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58018
Endocardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.731
KNS62	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80618
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
CRCGN016_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23205
PMC7826840__F4a	PFOCR Pathway Figure Associations 2024	1.0	null
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-LEUTX_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_LEUTX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5915057__F4	PFOCR Pathway Figure Associations 2023	1.0	null
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
modified	GeneRIF Biological Term Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030259
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71284
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Asthma	CTD Gene-Disease Associations	1.0	1.18193
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.828
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50154
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3975	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71864
Lymphoid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.02436
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
counteract	GeneRIF Biological Term Annotations	1.0	null
serve	GeneRIF Biological Term Annotations	1.0	null
nude	GeneRIF Biological Term Annotations	1.0	null
agent	GeneRIF Biological Term Annotations	1.0	null
Perturb_12371_KO_NR4A1_SRP293165	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.32845
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.36466
metastasis	GeneRIF Biological Term Annotations	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927339
tumour	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15763
Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K60807536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73052
proliferation	GeneRIF Biological Term Annotations	1.0	null
BRD-K15532741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72568
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661929
vivo	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.093
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01132
a-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.734735
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.07492
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122763
BRD-K29077209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21136
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8947
Gastric Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05291
BRD-K70511574_sunitinib_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0994
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426121
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94244
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liposarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.107754
status	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17313
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
il24	GeneRIF Biological Term Annotations	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4092
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92982
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
JAK1_druginhibition_165_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.33785
BRD-K30632097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19099
GTEX-XUJ4-0926-SM-4BOPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888076
Multiple Sclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01243
LB-65-SM65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.852037
BRD-K45947503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21315
BRD-K48994888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83725
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
therapy	GeneRIF Biological Term Annotations	1.0	null
stress	GeneRIF Biological Term Annotations	1.0	null
increased heart weight	IMPC Knockout Mouse Phenotypes	1.0	null
OUMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.55055
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41554
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10157
PMC5751286__F2	PFOCR Pathway Figure Associations 2024	1.0	null
myeloid	GeneRIF Biological Term Annotations	1.0	null
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870335
Integrin alphav-beta5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.28827
treatment	GeneRIF Biological Term Annotations	1.0	null
GSE211177,GSE211178_4_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
p1Lim part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27616
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.962
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52602
LPS853	DepMap CRISPR Gene Dependency	1.0	5.65928
mapk	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01971
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
helveticoside-2192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6791
Perturb_9820_KD_LMO1_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27274
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
mefloquine-5724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
FF-34-KW62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.4366
Influenza	DisGeNET Gene-Disease Associations	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
cellular	GeneRIF Biological Term Annotations	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
marginal	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.175
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
17823238-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987769
interferongamma	GeneRIF Biological Term Annotations	1.0	null
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.22773
Mesothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851697
Skin-muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	7.54984
BRD-K27823380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26118
psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182957
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
AE-52-NW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.339875
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303559
Four-helical cytokine, core	InterPro Predicted Protein Domain Annotations	1.0	null
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
senescent	GeneRIF Biological Term Annotations	1.0	null
oncogenes	GeneRIF Biological Term Annotations	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36264
BRD-K01283689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30009
Leukemia	CTD Gene-Disease Associations	1.0	1.20751
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69762
response to wounding	GO Biological Process Annotations 2015	1.0	null
BRD-K81544427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49472
revealed	GeneRIF Biological Term Annotations	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4875
interleukin-27 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.299
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.2212
PBX3	ENCODE Transcription Factor Targets	1.0	null
Urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.229
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4457
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02028
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69728
GB-64-HC34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354362
U-373MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12419315-medi-104-e44180-s001.xlsx-Table_S4-MR_estimates_of_PCa_on_ninety-one_inflammatory_cytokines_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_190_KD_Slpi_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.02605
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.56581
BRD-K73880067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60153
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
colo741	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
cd8	GeneRIF Biological Term Annotations	1.0	null
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04482
KMS34	DepMap CRISPR Gene Dependency	1.0	5.07338
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79377
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.71426
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.904148
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.496771
ELF1	ENCODE Transcription Factor Targets	1.0	null
Regulatory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.921
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.288315
RPMI-7951 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.886551
Skin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1559
PMC11891720-mmc1.docx-0-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.1617
Integrin alphav-beta6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
BRD-K85336956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02831
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
migratory	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
mandatory	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Calprotectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.312
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
kills	GeneRIF Biological Term Annotations	1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
troglitazone-1173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04669
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121671
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05624
butyl hydroxybenzoate-3069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KB-49-NF63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.647507
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48864953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57874
lycorine-3808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7767_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BE-90-YK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362478
CAPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06399
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
Perturb_16740_KO_Gcn5_SRP271119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.2215
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.0303
MITF_01_24	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.79007
HB-54-ZC59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.444835
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62574
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
negatively	GeneRIF Biological Term Annotations	1.0	null
negative regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
Perturb_8813_KD_YAP1/WWTR1_SRP284279	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.2902
mrc9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
BRD-K60287661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64671
protein-dna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.620104
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
p38	GeneRIF Biological Term Annotations	1.0	null
BRD-A97759891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46389
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12313
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
BRD-K82477786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12731
BRD-K97223487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.063
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05437
promotes	GeneRIF Biological Term Annotations	1.0	null
BRD-K82671459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00334
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978005
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.418768
Encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
Primary cutaneous T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
AG-013608-5949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mode	GeneRIF Biological Term Annotations	1.0	null
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213714
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Hyper IgE recurrent infection syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0986
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08539
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.182743
U-87MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
melanocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ergocalciferol-2442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3826
arsenic trioxide	CTD Gene-Chemical Interactions	1.0	null
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
BRD-K17059629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00164
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01033
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Keratinocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.709
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.26062
Vaginal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
reducing	GeneRIF Biological Term Annotations	1.0	null
mdr	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_74_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985646
Rh-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
response to stress	GO Biological Process Annotations 2015	1.0	null
induction	GeneRIF Biological Term Annotations	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.915264
BRD-K24393110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26012
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
toward	GeneRIF Biological Term Annotations	1.0	null
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12228
BRD-K68002543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2784
Chronic urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.427
Pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.388
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863903
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886521
Peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.87614
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9785
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
markedly	GeneRIF Biological Term Annotations	1.0	null
their	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular component movement	GO Biological Process Annotations 2015	1.0	null
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.46
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
Malignant Pleural Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_11441_KO_TP53_SRP253428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.14152
Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07755570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08751
ovary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161863
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.871
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
potent	GeneRIF Biological Term Annotations	1.0	null
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
8-azaguanine-1833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL20RA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
causing	GeneRIF Biological Term Annotations	1.0	null
DE-30-UR76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.498473
single-organism process	GO Biological Process Annotations 2015	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.16102
hdac4	GeneRIF Biological Term Annotations	1.0	null
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.141
Umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hyper IgE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0442
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12779
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.82227
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
JD-87-KA71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345641
antimycin A-2098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3004
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A55153871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87536
Her2-Negative Breast Cancer	DisGeNET Gene-Disease Associations	1.0	null
rescinnamine-2130	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MIR122_OE_GDS3470_573_human_Embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06245
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958636
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01241
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18646
PMC12695664-41588_2025_2410_MOESM4_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932126
inos	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6796-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
Breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.869
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
regulation of tyrosine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
PMC3805541__F3	PFOCR Pathway Figure Associations 2023	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3742913__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Gall bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51924
interleukin-12 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Urease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
PMC6532024__F3	PFOCR Pathway Figure Associations 2024	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7373-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hydroxyzine-1941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.44409
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01675
BRD-K68328788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06313
produced	GeneRIF Biological Term Annotations	1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1076
tetramisole-4412	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6397
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
source	GeneRIF Biological Term Annotations	1.0	null
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
HD-29-LW24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353321
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975142
Perturb_15437_KD_NUSAP1_SRP074246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.84904
protein modification process	GO Biological Process Annotations 2015	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07309
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphangiogenesis	GeneRIF Biological Term Annotations	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40378
Rectum adenocarcinoma_READ_TCGA-EI-6881-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naringenin-4597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
route	GeneRIF Biological Term Annotations	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K78217087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19101
GTEX-Q2AH-0226-SM-48U1I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21737
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2C-20629094-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4259415-oncotarget-05-10198-s002.xlsx-Sheet1-STAT3_Pathway_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.503099
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930148
BRD-K11630986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11258
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K78983822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13506
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2613
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947459
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18428
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
MOVAS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5719
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.571226
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226219
AB-21-VE32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247444
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
agdriven	GeneRIF Biological Term Annotations	1.0	null
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.245
Apocrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
BRD-K63800697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00726
Perturb_12953_KO_ZFP36L2_SRP251843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.47037
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71762
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
cd34positive	GeneRIF Biological Term Annotations	1.0	null
PPARD-23176727-KERATINOCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11516_KD_L1CAM_SRP076162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.66714
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17294
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833797
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
intracranial	GeneRIF Biological Term Annotations	1.0	null
BAK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.774
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5215
PMC5742522-peerj-05-4214-s004.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_AND_strabismic_lateral_rectus_LR_vs_donor_LR_experiments_COMBINED_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37751
GSE126463_5_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
peptidyl-serine modification	GO Biological Process Annotations 2015	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4807
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616183
BRD-K88135858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06034
18160665-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
pancreatic	GeneRIF Biological Term Annotations	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22145
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-29-HQ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293688
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46298577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42973
lines	GeneRIF Biological Term Annotations	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15465
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06912
orciprenaline-2485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38191
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.963194
Keratitis	DisGeNET Gene-Disease Associations	1.0	null
positive regulation of cysteine-type endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cassettes	GeneRIF Biological Term Annotations	1.0	null
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881987
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00859
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67337
hepatoma	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843957
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0651
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88314
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8786
establish	GeneRIF Biological Term Annotations	1.0	null
PMC9550700__F7	PFOCR Pathway Figure Associations 2024	1.0	null
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
inhibition	GeneRIF Biological Term Annotations	1.0	null
il10	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5289
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856974
Mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.333
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
azaperone-6151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE209533_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949762
CRCGN016_MCF10A.TP53.M_24H:L24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00932
proteosome-associated autoinflammatory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
serum	GeneRIF Biological Term Annotations	1.0	null
Perturb_2834_KD_ESR1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5916
POLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537161
Astrocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
pustulosis	GeneRIF Biological Term Annotations	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-RAF_UP_V1_DN-Ensemble_gene_ID_ZHX2	Rummagene Transcription Factor Associations 2026	1.0	null
induce	GeneRIF Biological Term Annotations	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.04031
LXF-289	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57557
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98393
genistein-5595	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ifngamma	GeneRIF Biological Term Annotations	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23429
alpha	GeneRIF Biological Term Annotations	1.0	null
Carcinoma	CTD Gene-Disease Associations	1.0	1.63563
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850573
BRD-K75534737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38124
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K58408512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48306
PMC4647707__F4	PFOCR Pathway Figure Associations 2023	1.0	null
GSE138789_0_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
differentiation	GeneRIF Biological Term Annotations	1.0	null
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72663
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.161
lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05677
BRD-A67788537_Salermide_PC3_24.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
digoxigenin-3060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
KML1	DepMap CRISPR Gene Dependency	1.0	2.14318
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07733
PMC6013441__F4	PFOCR Pathway Figure Associations 2024	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64021
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Interleukin-20 family signaling	Reactome Pathways 2024	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
PMC4596691__F4	PFOCR Pathway Figure Associations 2024	1.0	null
OE-75-WF43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.929763
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
IgD B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55249
BRD-K90821428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31141
Bronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
cellular response to molecule of bacterial origin	GO Biological Process Annotations 2015	1.0	null
Penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
PMC10891378-tau-13-01-91-supplementary.pdf-116-ZNF683_ZNF683	Rummagene Transcription Factor Associations 2026	1.0	null
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
B-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.249
reported	GeneRIF Biological Term Annotations	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27451
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.886882
Serum Albumin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
structural	GeneRIF Biological Term Annotations	1.0	null
BRD-K70695911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0839
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
BRD-K77601667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27011
Apocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
DB-24-CQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372278
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.657
promising	GeneRIF Biological Term Annotations	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0715
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.6595
Skin-cd1c-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	1.29082
MEF2A	ENCODE Transcription Factor Targets	1.0	null
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
functions	GeneRIF Biological Term Annotations	1.0	null
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.255202
Adult Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
reversal	GeneRIF Biological Term Annotations	1.0	null
upon	GeneRIF Biological Term Annotations	1.0	null
modulation	GeneRIF Biological Term Annotations	1.0	null
Perturb_710_KO_DNMT1_SRP389363	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.70646
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.386
abnormal	GeneRIF Biological Term Annotations	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92749
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642454
transgenic	GeneRIF Biological Term Annotations	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.645786
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22926
separate	GeneRIF Biological Term Annotations	1.0	null
interleukin	GeneRIF Biological Term Annotations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65924
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lung	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
impact	GeneRIF Biological Term Annotations	1.0	null
Immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.213
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052766
Autoimmune disease of cardiovascular system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14998
Prepuce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56388
Chlorosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35758
Melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4732-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7036277-peerj-08-8662-s005.xlsx-42_genes_were_downregulated_in-Supplemental_Table_S3_42_genes_were_downregulated_in_the_EN2-Eca109_cells_as_compared_with_the_NEO-Eca109_cells_Related_to_Figure_5A_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
Colitis	CTD Gene-Disease Associations	1.0	1.30666
pi3k	GeneRIF Biological Term Annotations	1.0	null
BRD-K01281780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0814
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10767
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1546
SNU324	CCLE Cell Line Gene CNV Profiles	1.0	1.43979
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.463
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3213
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
etoposide-1626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_16731_KO_Myc/Pin1_SRP069191	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.0849
Overview of proinflammatory and profibrotic mediators	WikiPathways Pathways 2024	1.0	null
SK-MEL-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
GSE199644_3_v_1_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:E02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0449
Hepatitis C, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07979
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44773
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916165
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC298	CCLE Cell Line Gene Expression Profiles	1.0	3.40758
pleura	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189992
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06763
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7385
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966922
memory	GeneRIF Biological Term Annotations	1.0	null
18849563-SuppTable5a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0579
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8785
GSE139455_7_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3473-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12339
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.468
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849143
lethality	GeneRIF Biological Term Annotations	1.0	null
ESR1-22217937-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28601
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29175
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89554
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.76
hiv infections; [x]human immunodeficiency virus disease	GAD Gene-Disease Associations	1.0	null
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K46308702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0183
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.54435
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32325
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mutagenesis	GeneRIF Biological Term Annotations	1.0	null
BRD-K34252131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42149
Perturb_11102_KO_Tpt1_SRP214000	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.55644
cytokines	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979907
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1725
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
temozolomide	GeneRIF Biological Term Annotations	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8627
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00063
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01087
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.063
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44799
Laryngeal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15087476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63448
Pulmonary artery smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5318
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22587
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.204039
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Miscarriage	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044335
RERFLCMS	CCLE Cell Line Gene Expression Profiles	1.0	1.49037
Perturb_11964_KO_BATF_SRP401628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HIC1_01_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.93949
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AsPC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1139
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.10753
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839554
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pruritus	CTD Gene-Disease Associations	1.0	1.12048
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-10-GX45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04922
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Perturb_3013_KO_TLE4_SRP298305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.44754
Pustulosis of palm and sole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08604
upregulation	GeneRIF Biological Term Annotations	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.923225
Breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
tropine-6147	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver	GeneRIF Biological Term Annotations	1.0	null
Bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.613
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64339
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5958
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892029
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228196
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923649
Arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
BRD-K94936556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19372
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
FOSL2	ENCODE Transcription Factor Targets	1.0	null
CARD11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00612242
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70243
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
EP300_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13761649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48895
AB-71-CI37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.20592
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2889
Respiratory epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.574
including	GeneRIF Biological Term Annotations	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
GSE126463_4_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34942615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02502
Lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K76664579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0369
reduced	GeneRIF Biological Term Annotations	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55016
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885879
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
BRD-K82674931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38707
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.467807
Biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106454
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52988
Hemorrhage	CTD Gene-Disease Associations	1.0	1.41613
Anemia	CTD Gene-Disease Associations	1.0	1.21631
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48501
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513948
Perturb_3883_KO_RELB_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972702
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2816
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1372
CRCGN015_MCF10A.WT.HP_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05274
Perturb_12932_KD_DHODH_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61344
Perturb_12260_KD_IGF2BP2_SRP334258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19978
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54556
SC-25-HE80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.502369
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.24591
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071343
ARHGDIB_Transfection_GDS4455_551_human_UM-UC-3 bladder carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K49345010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28926
SNU601	DepMap CRISPR Gene Dependency	1.0	2.57661
GATA3	ENCODE Transcription Factor Targets	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87383650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10527
BRD-K65836113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63516
Urinary bladder cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
Prune Belly Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.52117
Precursor Cell Lymphoblastic Leukemia-Lymphoma	CTD Gene-Disease Associations	1.0	1.13075
MYC	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K03659510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20756
PMC4596691__F4	PFOCR Pathway Figure Associations 2023	1.0	null
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
Prostate gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
Irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1551
PMC5013636-ncomms12601-s5.xlsx-ETS2-Groups_ETS2	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.04441
Perturb_1161_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.70083
Glioblastoma multiforme cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
sparing	GeneRIF Biological Term Annotations	1.0	null
BRD-K42805893_HG-14-8-02_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
utr	GeneRIF Biological Term Annotations	1.0	null
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6502
ESR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K70875838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31205
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_14146_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.93003
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160119
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32556
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
subfamily	GeneRIF Biological Term Annotations	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69864
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00903
bucladesine-2741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.157
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.684207
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
BRD-K33863933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01776
first	GeneRIF Biological Term Annotations	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10531214__F4	PFOCR Pathway Figure Associations 2024	1.0	null
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
fluspirilene-3086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K71357636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44964
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.55093
histone	GeneRIF Biological Term Annotations	1.0	null
BRD-K37770214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32425
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3784
oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
apoptotic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857405
Transcription factor AP-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
akt	GeneRIF Biological Term Annotations	1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
demonstrate	GeneRIF Biological Term Annotations	1.0	null
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LLC-RK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
opportunity	GeneRIF Biological Term Annotations	1.0	null
Vaccinia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41123
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6497
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Bronchoalveolar lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
Respiratory Tract Diseases	CTD Gene-Disease Associations	1.0	1.19213
CE-03-YQ91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.424979
BD-69-XG81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626427
different	GeneRIF Biological Term Annotations	1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GBC-SD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.53391
BRD-K59843356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81525
NCIH292	CCLE Cell Line Gene Expression Profiles	1.0	1.40099
atypical	GeneRIF Biological Term Annotations	1.0	null
Perturb_2595_KD_SMURF1_SRP115428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
neuroblastoma	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20667
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protriptyline-5438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD3	ChEA Transcription Factor Targets	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44123
trabecula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642858
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CRTAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522702
STAT3	ChEA Transcription Factor Targets	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.536183
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837253
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23095
PMC10561055-mmc3.xlsx-LPS_T0-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
host cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183025
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6852
immune system process	GO Biological Process Annotations 2015	1.0	null
Pulmonary fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
BRD-K65245206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07037
BRD-K83721789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42378
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05799
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-74-QN56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.56809
Synovitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151782_6_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
correlates	GeneRIF Biological Term Annotations	1.0	null
BRD-K03370561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10281
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
PMC7498011__F5	PFOCR Pathway Figure Associations 2024	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	2.11549
influence	GeneRIF Biological Term Annotations	1.0	null
synthesis	GeneRIF Biological Term Annotations	1.0	null
Lymphoid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.955
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13042
sanguinarine-2927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	4.73822
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.662859
ECGI10	CCLE Cell Line Gene Expression Profiles	1.0	1.8087
BRD-K47349225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44348
ULK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053597
BRD-K95129711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06217
ticlopidine-1895	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CB-99-OG76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275426
L33	DepMap CRISPR Gene Dependency	1.0	3.05732
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_757_KO_DNMT3B_SRP389363	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.68502
biology	GeneRIF Biological Term Annotations	1.0	null
Chronic Idiopathic Urticaria	DisGeNET Gene-Disease Associations	1.0	null
PMC6895828__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K52872067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23854
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.545
BRD-K24422491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24549
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM793	CCLE Cell Line Gene Expression Profiles	1.0	1.45125
negative regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
guanabenz-1961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
appendices_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.05429
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.30421
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03935
Urticaria	DisGeNET Gene-Disease Associations	1.0	null
PMC9730246-Table_7.xlsx-LPS_Val_up-Upstream_Regulator_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88295
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.306632
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
SMC3	ENCODE Transcription Factor Targets	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01208
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.602987
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830699
diseasefree	GeneRIF Biological Term Annotations	1.0	null
Biofilm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308122
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.330295
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215977
BRD-K34851865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03567
Prostate carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.244696
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833852
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7543
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_DN_NR2F1_ind_DN-D_HEP3_DN_NR2F1_Ind_DN_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54824
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866125
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.658272
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.19399
positive regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
thioridazine-1171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
1br3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28316
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434957
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912892
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.907058
PMC12703266-gutjnl-75-1-s002.pdf-29-TBX21_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
necrosis	GeneRIF Biological Term Annotations	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
BRD-K18043221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69681
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38502
spironolactone-2064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
local	GeneRIF Biological Term Annotations	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
PMC4919052__F10	PFOCR Pathway Figure Associations 2024	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558457
Microphthalmia	DisGeNET Gene-Disease Associations	1.0	null
Signaling by Interleukins	Reactome Pathways 2024	1.0	null
DAUDI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
alcuronium chloride-4409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64535513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02636
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
requiring	GeneRIF Biological Term Annotations	1.0	null
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735147
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.355
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44253
PMC7902901-Table_12.xlsx-NFKB1-Unnamed_7_NFKB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65706
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302478
Peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.333
thioridazine-4085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UE-58-EW15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203258
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399398
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
17823238-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
cc90	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4188
Gall bladder cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
mutz1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
mmp7	GeneRIF Biological Term Annotations	1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SUP-M2	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.401413
regulator	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12667_OE_MX2_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.54136
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78848
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52635
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064022
transduction	GeneRIF Biological Term Annotations	1.0	null
M14 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	1.5101
Adult Burkitt Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K23430426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03196
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
PMC11979991-mmc1.xlsx-12_AP1-E2F_targets_CIB-MG-Gene_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2431
PMC3382204__F5	PFOCR Pathway Figure Associations 2023	1.0	null
multifunctional	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32462
gliomas	GeneRIF Biological Term Annotations	1.0	null
sensitizing	GeneRIF Biological Term Annotations	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8525330__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Perturb_3882_KO_ITPR3_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05581
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
CB-88-LG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367448
Decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
alpha-beta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
BRD-K34382498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10043
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6512
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01717
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10329
Arthritis, Juvenile Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873914
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
positive regulation of cell death	GO Biological Process Annotations 2015	1.0	null
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.294053
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12665_KD_SLNCR_SRP151199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.08385
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3584
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.15458
similar	GeneRIF Biological Term Annotations	1.0	null
inhibiting	GeneRIF Biological Term Annotations	1.0	null
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.758615
BRD-K39925250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00879
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31778
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38224
beta-escin-4544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15752
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846983
other	GAD High Level Gene-Disease Associations	1.0	0.293278
18849563-SuppTable5c	GeneSigDB Published Gene Signatures	1.0	null
Laryngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
guanabenz-4642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
injection	GeneRIF Biological Term Annotations	1.0	null
splicing	GeneRIF Biological Term Annotations	1.0	null
Pemphigoid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19544
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab8_TRIM11-KD-up_genes-Table_8_Up-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73717
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385143
BRD-K07914894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73104
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.168
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.672786
CAV3_KO_GDS3533_17_mouse_mammary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Actinic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
acetylation	GeneRIF Biological Term Annotations	1.0	null
adenoviruses	GeneRIF Biological Term Annotations	1.0	null
here	GeneRIF Biological Term Annotations	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
Decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4484
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120752
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
18849563-SuppTable3a	GeneSigDB Published Gene Signatures	1.0	null
HL-7702 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402144
Disseminated Malignant Neoplasm	DisGeNET Gene-Phenotype Associations	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20726
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14739
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
RCOR1	ENCODE Transcription Factor Targets	1.0	null
thioridazine-1230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
norcyclobenzaprine-4190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
interacting	GeneRIF Biological Term Annotations	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.80106
inflammation	GeneRIF Biological Term Annotations	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849089
Perturb_14154_KD_RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.9113
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069909
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283207
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91269
propoxycaine-6803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.55297
PMC3607232-mmc3.xlsx-RUNX1_targets_in_K562_and_SEM-x_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
PMC11979991-mmc1.xlsx-12_AP1-E2F_targets_CIB-MG-ensembl_id_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
clonidine-1555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26657
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.8037
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22504
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
fluphenazine-1237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FEN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533983
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05058
Superior colliculus, motor related, deep white layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25608
Craniofacial Abnormalities	CTD Gene-Disease Associations	1.0	1.09083
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57111
EPLC272H	CCLE Cell Line Gene Expression Profiles	1.0	2.13747
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77115
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
host cell nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.609086
Glioma	DisGeNET Gene-Disease Associations	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3685
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19723
localization	GeneRIF Biological Term Annotations	1.0	null
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106511
mRNA_STAT3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
BRD-A56592690_PX12_PL21_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89008
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.734262
Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.443
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04235
BRD-K82793574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76527
BD-01-RI07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26279
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.64
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76383
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478145
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6601
sulindac sulfone	CTD Gene-Chemical Interactions	1.0	null
S100A9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.931
8-azaguanine-1791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K94657740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35014
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15722
transcription	GeneRIF Biological Term Annotations	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62000282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49156
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
response to external biotic stimulus	GO Biological Process Annotations 2015	1.0	null
Apoptotic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
ANGPTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34399
damage	GeneRIF Biological Term Annotations	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A375	GDSC Cell Line Gene Expression Profiles	1.0	1.81075
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01419
HEC50B	DepMap CRISPR Gene Dependency	1.0	2.76674
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39264
Endoplasmic reticulum chaperone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
il22	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41714
temozolomide	CTD Gene-Chemical Interactions	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72582
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973421
GSE185163_5_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46439
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24518
Extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.611
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.02847
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993977
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00213
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gastric	GeneRIF Biological Term Annotations	1.0	null
BRD-K76015448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1392
Lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.532
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6167
HS706T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06283
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.24682
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
action	GeneRIF Biological Term Annotations	1.0	null
DB-56-XL71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.14973
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4978
WRL-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
complete	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20131
BRD-K90103010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01457
RFX5	ENCODE Transcription Factor Targets	1.0	null
cuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17719
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53125
Pneumonia	CTD Gene-Disease Associations	1.0	1.10246
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36037
Perturb_14156_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EPLC-272H	GDSC Cell Line Gene Expression Profiles	1.0	1.77532
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.242
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
possibly	GeneRIF Biological Term Annotations	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12496
multiple	GeneRIF Biological Term Annotations	1.0	null
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.412405
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079211
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
mda7il24gas3beta1integrinfibronectin	GeneRIF Biological Term Annotations	1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28436
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18559
Perturb_12664_KD_SLNCR_SRP151199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.291539
prochlorperazine-1156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
19192944-TableS4	GeneSigDB Published Gene Signatures	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27037
T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
thioredoxin	GeneRIF Biological Term Annotations	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.427729
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
positive regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15811
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Salmonellosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
BRD-K94325918_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937451
discriminating	GeneRIF Biological Term Annotations	1.0	null
gallbladder	GeneRIF Biological Term Annotations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Perturb_1122_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.3777
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02279
SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7902901-Table_12.xlsx-MITF-Unnamed_7_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
viable	GeneRIF Biological Term Annotations	1.0	null
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38583
hep-3b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59405
Rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
thapsigargin-7103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06363
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06487
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.879725
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_DN_AA_DN-D-HEP3_DN_AA_DN_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Smallpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.62674
CD47	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490604
malignant	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05397
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049667
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1626
Eukaryotic translation initiation factor 4F complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	2.17299
GSE153871_0_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Epithelial stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17267
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08745
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40221
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
Early Pregnancy	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892556
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cellular response to lipopolysaccharide	GO Biological Process Annotations 2015	1.0	null
iii	GeneRIF Biological Term Annotations	1.0	null
piperine-1327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.0949
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
ras	GeneRIF Biological Term Annotations	1.0	null
Her2-Positive Carcinoma Of Breast	DisGeNET Gene-Disease Associations	1.0	null
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837448
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54302
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42766
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.04412
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
AB-85-JR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511491
PMC8639500__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15203
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165334_3_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vitiligo	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06527
CD86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00614235
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2035
il22r1il20r2	GeneRIF Biological Term Annotations	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13471
wi-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59646
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-88-PW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395408
cytokine activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20347
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067173
germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
Hidradenitis suppurativa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
Ankylosing spondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
erk12	GeneRIF Biological Term Annotations	1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.44791
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.75915
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947459
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21596
BRD-K84320538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41967
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13788
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01516
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
ppp	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13233
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.406
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
animals	GeneRIF Biological Term Annotations	1.0	null
PMC10248509-Data_Sheet_5.CSV--Autophagy_AND_GSE41177_DE-Genes_NOT_GSE58294_DE-genes_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4919052__F10	PFOCR Pathway Figure Associations 2023	1.0	null
inhibits	GeneRIF Biological Term Annotations	1.0	null
CJM	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928861
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5033
BC-43-PD20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297855
Skin-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	7.2301
nfkappab	GeneRIF Biological Term Annotations	1.0	null
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02718
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
calcification	GeneRIF Biological Term Annotations	1.0	null
BRD-K19590405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66217
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
BRD-K70408591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6451
Perturb_12897_KO_NCOR1_SRP319377	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.77947
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-357 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
BRAF_drug inhibition_GSE42872_368_human_A375	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Extrinsic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
regulation of cell migration	GO Biological Process Annotations 2015	1.0	null
BxPC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26213
du145	GeneRIF Biological Term Annotations	1.0	null
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.326152
BAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77792
hyperplasia	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03095
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00213
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048581
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26852
Oral cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060317
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA3Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
PMC9437808-mmc5.xlsx-Upstream_regulators-IPA_Upstream_regulator_analysis_genes_that_were_downregulated_in_the_cf-mRNA_of_AZD_treated_group_at_2-hour_post_LPS_time_point_were_used_as_inputs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.437983
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88384
Weight Loss	CTD Gene-Disease Associations	1.0	1.38696
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.58561
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98424
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85162
DD-89-HG56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.240663
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
QPCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46157
cytokine activity	GO Molecular Function Annotations 2025	1.0	null
cellcell	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.540036
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.48751
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13252
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nso	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848273
lymphocytic	GeneRIF Biological Term Annotations	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87439
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to organic substance	GO Biological Process Annotations 2015	1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214983
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K59041191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16936
Goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12759
PMEPA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00626343
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
P69 prostate cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
HB1.F3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
leukemia	GeneRIF Biological Term Annotations	1.0	null
PMC10561055-mmc3.xlsx-LPS_T2-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3	ChEA Transcription Factor Targets	1.0	null
Laryngeal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
TC32	CCLE Cell Line Gene CNV Profiles	1.0	1.4955
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Perturb_8729_KD_USP7_SRP256243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.92229
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
il19il20	GeneRIF Biological Term Annotations	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042063
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29793
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15405
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
murine	GeneRIF Biological Term Annotations	1.0	null
ethisterone-4340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TA-19-YA45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235933
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20433
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Tritocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
Adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.251
Fatty Liver	CTD Gene-Disease Associations	1.0	1.82341
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65048
Asthma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gall bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
PMC10040389-mmc7.xlsx-URs_IMIDs_SP1_6-UR_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11211652-j_pp-2024-0001_suppl_001.pdf-8-SNAI1_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular response to cytokine stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K74803017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12831
QE-93-PG25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200063
18362358-Table10	GeneSigDB Published Gene Signatures	1.0	null
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27726
20096135-Table3	GeneSigDB Published Gene Signatures	1.0	null
synergizes	GeneRIF Biological Term Annotations	1.0	null
achn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350372
LN319	DepMap CRISPR Gene Dependency	1.0	3.37897
BRD-K54872884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47056
Perturb_2704_KD_FOXQ1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33927
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
essential	GeneRIF Biological Term Annotations	1.0	null
Dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Bcl-2 family protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
Car cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
synthase	GeneRIF Biological Term Annotations	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04296
HA-17-MS45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.850816
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Hepatitis C	DisGeNET Gene-Disease Associations	1.0	null
Fungal esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1205
larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143013
Melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.182
neonatal	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-203a	MiRTarBase microRNA Targets	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
receptors	GeneRIF Biological Term Annotations	1.0	null
PMC7902901-Table_12.xlsx-FOS-Unnamed_7_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81751
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46884
independent	GeneRIF Biological Term Annotations	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_2820_KD_Src_SRP194728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
immune response	GO Biological Process Annotations 2015	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.34897
Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.72235
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32054
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0519
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05674
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42659
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.956
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.596
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03811
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9884
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01095342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29476
Sarcoma_SARC_TCGA-IW-A3M6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
PMC3500769-srep00875-s3.xls-AP1-Time_24_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12419315-medi-104-e44180-s001.xlsx-Table_S1-MR_estimates_of_ninety-one_inflammatory_cytokines_on_PCa_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135350_2_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
flunisolide-3747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
dipyridamole-1517	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
colonyforming	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rh-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59304
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57723
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.962747
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07907
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.511386
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16584
BRD-K43224838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21613
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22135
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97579
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_755_KD_ZFR_SRP107875	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.62892
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.63091
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949274
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17863
capacity	GeneRIF Biological Term Annotations	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9923
glycocholic acid-2454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Psoriasis 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877801
major depressive disorder	GAD Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
BRD-K61623863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36259
IL23-mediated signaling events	PID Pathways	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.17168
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23528
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915299
BRD-K27540772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04593
PD-60-FM93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.579874
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83459
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
triggers	GeneRIF Biological Term Annotations	1.0	null
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250217
phosphatidylinositol 3-kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.221025
ehrlich ascites carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307889
haplotype	GeneRIF Biological Term Annotations	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76364
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869807
SOX4_01_260	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.76918
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
hsa-miR-764	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0711
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15985
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GM133	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
BRD-K10276373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33556
ganciclovir-6289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05411
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
BEAS-2B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
STAT6-20620947-CD4-POS-T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
negative regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AD-00-WA10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.880893
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.195
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.98273
Lung squamous cell carcinoma_LUSC_TCGA-66-2744-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58689
HEC1	DepMap CRISPR Gene Dependency	1.0	2.24151
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.51582
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97351
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.0493
improved	GeneRIF Biological Term Annotations	1.0	null
cycle	GeneRIF Biological Term Annotations	1.0	null
ID-90-NM43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.33209
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Recurrent Urinary Tract Infection	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47349
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5003
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.961062
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.978202
cytosolic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081181
PMC7902901-Table_12.xlsx-CREB1-Unnamed_7_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45042519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14694
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867247
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1422
lymph	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03835
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68146
BRD-K00773626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27415
Respiratory Syncytial Virus Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946404
Perturb_539_OE_EWS_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.38003
16740760-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.33339
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0227
Leishmaniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.703283
Synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0619
MEL270	DepMap CRISPR Gene Dependency	1.0	5.99104
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
terguride-6299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
huh-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50275
kidney cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704764
digoxin-2423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.393226
cicloheximide-5743	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-2667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE138789_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
pathophysiology	GeneRIF Biological Term Annotations	1.0	null
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
cell death	GO Biological Process Annotations 2015	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.63451
levomepromazine-3701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240497
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22379
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
PMC10794847-mmc2.xlsx-PBRM1_KD_down-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fc receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
clenbuterol-1613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
etynodiol-3102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83690550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55308
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
syrosingopine-1761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235804
XBP1_OE_GDS2861_60_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
o6methylguaninedna	GeneRIF Biological Term Annotations	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.74059
l-02 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.791044
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.400061
Rectum adenocarcinoma_READ_TCGA-AG-4022-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.42805
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33626
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17679
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06056
fourth	GeneRIF Biological Term Annotations	1.0	null
NCIH508	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53457
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7642
PMC8851354-Table_5.xlsx-FUS-DDIT3_reg_FD-bound-Supplementary_Table_5_Genes_regulated_by_FUS-DDIT3_that_are_FUS-DDIT3_targets_in_MLS_402-91_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.11769
family	GeneRIF Biological Term Annotations	1.0	null
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
B cell deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08248
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
U031	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43766
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
BRD-K22679163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58609
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22168
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66998
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	1.0	0.966931
Perturb_17145_OE_Xbp1_ERP110244	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7386
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312201
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.826331
B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913533
Methoxychlor	CTD Gene-Chemical Interactions	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.264
retrorsine-2784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AE-51-ZO26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.908788
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22906
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
PMC11979991-mmc1.xlsx-13_AP1-E2F_targets_Cycl-Quies-ensembl_id_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.14217
Lung squamous cell carcinoma_LUSC_TCGA-21-1079-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826916
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71762
PMC7470101__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938299
Perturb_15540_KD_Chd1_SRP201304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.83134
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A59449038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23327
Nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059166
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.37646
DE-98-FC24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.625728
tnfalpha	GeneRIF Biological Term Annotations	1.0	null
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30644
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9275
myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078736
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.23134
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
hsa-miR-4305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
oprs1	GeneRIF Biological Term Annotations	1.0	null
BRD-K66941670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80028
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
apoptosis	GeneRIF Biological Term Annotations	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4425
PMC7537965__F1	PFOCR Pathway Figure Associations 2023	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.11945
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
JUND_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
having	GeneRIF Biological Term Annotations	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853003
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28813
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991939
showed	GeneRIF Biological Term Annotations	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.800437
prdm1_00000000_e9dot5_placenta_lof_mouse_gpl6887_gse39584	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.174325
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374613
STAT1	ENCODE Transcription Factor Targets	1.0	null
Nasopharyngeal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62031
Adenoma	CTD Gene-Disease Associations	1.0	1.32577
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969781
PMC8851354-Table_2.xlsx-Genes_reg_by_FUS-DDIT3-Supplementary_Table_2_Genes_significantly_regulated_by_FUS-DDIT3_expression_in_HT1080_cells_adjusted_p-value_0_05_and_log2_Fold_change_1_or_-1_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03387
Perturb_12030_KD_ADORA1_SRP215261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
LOX IMVI	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.465
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.66786
PancreaticIslet	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.50552
EL-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2015	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.77724
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22379
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45667
dlx4_00000000_mcfdash7_gof_human_gpl201_gse21657	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.538592
Breast Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4652
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9148
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41204
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4131
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3892
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975199
FOXA1	ENCODE Transcription Factor Targets	1.0	null
DC-22-OP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303466
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699035
AC-75-CE67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.935032
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
major	GeneRIF Biological Term Annotations	1.0	null
BRD-K67859584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43504
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02196
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86872
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.23868
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.499614
Infant, Premature, Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Childhood Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
enhance	GeneRIF Biological Term Annotations	1.0	null
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13252
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86671
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91987
BRD-K07313741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75037
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Precursor B-Cell Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
fibroblast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09916
Pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28273
AM38	CCLE Cell Line Gene Expression Profiles	1.0	1.90551
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
wound	GeneRIF Biological Term Annotations	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Heparanase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
Gastroenteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
EHMT2_KD_GDS4800_315_human_MDA-MB231	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881987
Perturb_15558_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.35497
leads	GeneRIF Biological Term Annotations	1.0	null
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-153-JDP2_JDP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A87325732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77865
lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.68188
HCC44	CCLE Cell Line Gene Expression Profiles	1.0	1.63342
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.163641
BA-95-YU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263965
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42883
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
increased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052438
Null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.129
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0833
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945384
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.426993
GTEX-XBEW-1526-SM-4AT4K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936599
Perturb_173_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
proteasomes	GeneRIF Biological Term Annotations	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
DB-56-XL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.703329
M14	GDSC Cell Line Gene Expression Profiles	1.0	1.51478
Fc-epsilon receptor I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
(+)-isoprenaline-3046	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AD-54-FG24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.338355
Perturb_199_KD_Asns_SRP119932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.5528
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3688-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
non-small cell lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.18151
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dexamethasone-2079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_174_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12431
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212368
prognostic	GeneRIF Biological Term Annotations	1.0	null
Mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99252563_QL-XII-47_HS578T_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45296
Amyloidosis	DisGeNET Gene-Disease Associations	1.0	null
Mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942567
beta-escin-3807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
biological	GeneRIF Biological Term Annotations	1.0	null
BRD-K62203376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84074
20458058-TableS3b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900865
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05053
GSE48812_4_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904513
sirolimus-1148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUPM2	CCLE Cell Line Gene CNV Profiles	1.0	2.71305
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
complexes	GeneRIF Biological Term Annotations	1.0	null
BRD-K90655269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1868
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2576
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00562
such	GeneRIF Biological Term Annotations	1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29108
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1401
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxorubicin_homo sapiens_gpl96_gds3514	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42252
BRD-K36204977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05808
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.612134
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844685
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1395
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51036
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16702
BRD-K83697352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49304
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
viability	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18287
exerts	GeneRIF Biological Term Annotations	1.0	null
HEp-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235759
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
suppressing	GeneRIF Biological Term Annotations	1.0	null
alexidine-3699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939507
Prostate adenocarcinoma_PRAD_TCGA-CH-5738-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to biotic stimulus	GO Biological Process Annotations 2015	1.0	null
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1453
Advanced Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72474
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66632
Carcinoma, Non-Small-Cell Lung	CTD Gene-Disease Associations	1.0	1.01474
BRD-K50168500_S1019_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PLCB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00403287
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53265
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41204
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.0311
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7374
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74503
BRD-K96491043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27766
hsa-miR-4774-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
azacyclonol-1937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
BRD-K32145037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04884
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30719
RAF_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Multilymphoid progenitor cell_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.461901
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.56747
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.959
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
critical	GeneRIF Biological Term Annotations	1.0	null
Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28912
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92924
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1383
LB831-BLC	GDSC Cell Line Gene Expression Profiles	1.0	1.6418
glutamyl-tRNA(Gln) amidotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
mucosa	GeneRIF Biological Term Annotations	1.0	null
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41363
extended	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.16467
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6486
VA-06-DB75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250619
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nsaids	GeneRIF Biological Term Annotations	1.0	null
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109167
Uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
Prostate adenocarcinoma_PRAD_TCGA-HC-7079-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25517783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47352
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
Epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.334
cellular_component	GO Cellular Component Annotations 2015	1.0	null
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044448
BA-53-FM66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430315
Th17 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.861
HBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872045
BD-69-XG81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.422904
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827586
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978321
spondyloarthropathy	GeneRIF Biological Term Annotations	1.0	null
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276846
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
BRD-K10640729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41226
regulation of tyrosine phosphorylation of stat3 protein	GO Biological Process Annotations 2015	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4C_BATF3_downreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NHEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.556032
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
MutS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
Early Pregnancy Loss	DisGeNET Gene-Phenotype Associations	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05175
biochemical	GeneRIF Biological Term Annotations	1.0	null
renal cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148218
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25438
18849563-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
59M	DepMap CRISPR Gene Dependency	1.0	3.08856
CORL88	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05273
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626677
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277977
G361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54153
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
positive regulation of signaling receptor activity	GO Biological Process Annotations 2025	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_NCIH2073_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.4103
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Herpes simplex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21879
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEx SmallIntestine 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.03539
BRD-K55779851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02249
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354826
QA-58-CX23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.870379
PMC10873402__F5	PFOCR Pathway Figure Associations 2024	1.0	null
reticulum	GeneRIF Biological Term Annotations	1.0	null
response to lipopolysaccharide	GO Biological Process Annotations 2015	1.0	null
jak stat signaling pathway	KEGG Pathways	1.0	null
BRD-K33194123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2589
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
pleural fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214202
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
lymph node	HPA Tissue Gene Expression Profiles	1.0	1.24595
Perturb_1050_KD_MIA3_SRP344054	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.599139
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72397
ligands	GeneRIF Biological Term Annotations	1.0	null
distinct	GeneRIF Biological Term Annotations	1.0	null
negative regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.392888
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37127
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
develop	GeneRIF Biological Term Annotations	1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
rectum adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.301976
FOS	ENCODE Transcription Factor Targets	1.0	null
germinal	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86262
Perturb_16784_KD_CCNA1_SRP313541	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KG1C	CCLE Cell Line Gene Expression Profiles	-1.0	-2.46392
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36155
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLU	Pathway Commons Protein-Protein Interactions	1.0	null
fulvestrant-6197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.19745
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8836
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
nonmetastatic	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56754
Perturb_12108_KD_CCND1_SRP244245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.5558
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11082
Rheumatoid arthritis disease specific synovial tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.452
endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.801562
GTEX-S3XE-1326-SM-4AD4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04137
regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09192
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68233
Angioedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_16_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NR3C1	ENCODE Transcription Factor Targets	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.66771
pyrantel-5513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
respiratory system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.379626
HEP-3B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.55971
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446
MEF2A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9818_KD_GATA3_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.34642
BRD-K54198678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35743
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962618
hecogenin-5818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.637533
Perturb_12898_KO_NCOR1_SRP319377	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08115
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17342
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
discrete	GeneRIF Biological Term Annotations	1.0	null
BRD-K05402890_NCGC00165289-01_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ap1	GeneRIF Biological Term Annotations	1.0	null
preisthmic midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06002
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64339
PMC3609811__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
BRD-K56912308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15682
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
B-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.602
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.439332
positive regulation of tyrosine phosphorylation of stat3 protein	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07573
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.68
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
proapoptotic	GeneRIF Biological Term Annotations	1.0	null
penbutolol-2972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58358
tranylcypromine-7293	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_1302_OE_ERG/MYC_SRP069177	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.00338
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.03704
Allergic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40907
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07573
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23854
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30105551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30302
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22957
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345493
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28335
cd44	GeneRIF Biological Term Annotations	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
expense	GeneRIF Biological Term Annotations	1.0	null
BRD-K18253469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08928
FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Plasma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
Avellino Corneal Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944273
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.672913
acute myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090819
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
compelling	GeneRIF Biological Term Annotations	1.0	null
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
emetine-2145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
favoring	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71256
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063576
il20il24	GeneRIF Biological Term Annotations	1.0	null
BRD-K81144230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47661
PDE1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630813
SNU46	CCLE Cell Line Gene Expression Profiles	1.0	1.5811
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
MEL-JUSO	GDSC Cell Line Gene Expression Profiles	1.0	2.46243
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871595
IgD immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
Trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
fluticasone-2928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
QB-88-PG52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3328
GSE223241_2_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sp1	GeneRIF Biological Term Annotations	1.0	null
infected	GeneRIF Biological Term Annotations	1.0	null
understanding	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985733
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11083
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
lycorine-2195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_12049_KO_LSD1_SRP310135	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Papilloma	CTD Gene-Disease Associations	1.0	1.18326
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43153
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
15159021-table2	GeneSigDB Published Gene Signatures	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885163
Breast cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
J82	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64285
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20149
EE-85-SK26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367575
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54978
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307685
dosedependent	GeneRIF Biological Term Annotations	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00699
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
GTEX-XXEK-1226-SM-4BRUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55872
pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213621
Chronic inducible urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13681
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6FZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
class	GeneRIF Biological Term Annotations	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
involvement	GeneRIF Biological Term Annotations	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876288
Brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
myxoid liposarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.359657
suggests	GeneRIF Biological Term Annotations	1.0	null
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K98953112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05952
Perturb_538_OE_EWS_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.72654
crohns	GeneRIF Biological Term Annotations	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1467
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
CP66-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.43266
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04013
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.545224
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.175
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942718
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.4006
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SW-626 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.25
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73219
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987403
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621428
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.52541
ELK4	ENCODE Transcription Factor Targets	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.862111
Replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.833
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_13048_KO_Il33_SRP259135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8457
LL24 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
serine-type endopeptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.333
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4256
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380251
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07046
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
targeting	GeneRIF Biological Term Annotations	1.0	null
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
suppression	GeneRIF Biological Term Annotations	1.0	null
jak1stat	GeneRIF Biological Term Annotations	1.0	null
BRD-K04853698_-666_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Respiratory allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
origin	GeneRIF Biological Term Annotations	1.0	null
GTEx SmallIntestine 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-4.95061
without	GeneRIF Biological Term Annotations	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23162
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_350_OE_B3GNT2_SRP287831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Rhinitis	DisGeNET Gene-Disease Associations	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tumor Initiation	DisGeNET Gene-Phenotype Associations	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870335
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.789915
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40721
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6867
presenting	GeneRIF Biological Term Annotations	1.0	null
BRD-K78618254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44775
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21387
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
cephaeline-2429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
glioblastoma	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84054
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
BRD-K26156776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12138
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Mesenteric lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
CRCGN014_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27911
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
evidence	GeneRIF Biological Term Annotations	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
phosphoenolpyruvate-dependent sugar phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.903
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.659482
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00395
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951993
ID-90-NM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.519246
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231141
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71021
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18635
BRD-K29028138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23324
infection	GAD High Level Gene-Disease Associations	1.0	0.303208
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
amitriptyline-5453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50668
Lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.554
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
center	GeneRIF Biological Term Annotations	1.0	null
PMC8284339__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K27630941_N-(2-methoxyphenyl)-4-morpholino-6-(pyrrolidin-1-yl)-1,3,5-triazin-2-amine hw-gc-act01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAJI	DepMap CRISPR Gene Dependency	1.0	2.48897
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.13175
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01736
key	GeneRIF Biological Term Annotations	1.0	null
RBM17_02_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.41504
BRD-K32535831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61947
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974429
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08042
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.33242
PMC7902901-Table_12.xlsx-ATF3-Unnamed_7_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
vitro	GeneRIF Biological Term Annotations	1.0	null
dilazep-7364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35288418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54658
JA-63-WB39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.645542
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9533
A-498 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
plus	GeneRIF Biological Term Annotations	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.924356
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
eradicate	GeneRIF Biological Term Annotations	1.0	null
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9097
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
regulation of jak-stat cascade	GO Biological Process Annotations 2015	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83931
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Influenza A	DisGeNET Gene-Disease Associations	1.0	null
grhl3_16949565_skin_lof_mouse_gpl1261_gds2629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.658389
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1693
phosphatidylinositol 3-kinase complex, class iii	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.432618
CRCGN016_MCF10A.WT.HP_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03841
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40562
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27554
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dsbs	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01251
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21032
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01033
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.69446
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.509
Solid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971235
TRAMP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.345
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
Lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
guanfacine-5621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EA-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940207
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.40036
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853458
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828417
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18858
Neoplasm Invasiveness	CTD Gene-Disease Associations	1.0	1.5254
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21262
Perturb_3839_KO_RELB_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_19_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
myricetin-1334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315135
CE-18-AP85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.542854
Lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
Liver Diseases	CTD Gene-Disease Associations	1.0	1.51255
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35319
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_186_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.53855
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968461
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59083
BRD-K35863275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26432
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44084
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.173
Ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
KRAS.DF.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40361885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2732
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K35708212_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRO-AP2	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879058
Perturb_175_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.54796
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844914
negative regulation of cell motility	GO Biological Process Annotations 2015	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.44544
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65558
BRD-K33760911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1179
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
leukocytes	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
erk	GeneRIF Biological Term Annotations	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
prochlorperazine-2675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92982
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04588
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE155567_2_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.452
gadd45gamma	GeneRIF Biological Term Annotations	1.0	null
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
idoxuridine-1899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
promoter	GeneRIF Biological Term Annotations	1.0	null
rectal	GeneRIF Biological Term Annotations	1.0	null
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01185
BRD-K54115231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75459
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GSE196962_2_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid-6199	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0043
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epidermal	GeneRIF Biological Term Annotations	1.0	null
Glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.816
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49778
BACH1	ChEA Transcription Factor Targets	1.0	null
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56413
BRD-A26222320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26758
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.415337
lymphnode_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.25408
azathioprine-1945	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
suppress	GeneRIF Biological Term Annotations	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Adult Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.951534
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1453
Perturb_16783_KD_EIF3_SRP284164	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of cellular amine metabolic process	GO Biological Process Annotations 2015	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039108
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BD-90-DK64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222504
STAT6	ChEA Transcription Factor Targets	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
BC-10-OR76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.07982
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
hsa-miR-624	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09558
shsy5y	GeneRIF Biological Term Annotations	1.0	null
BRD-K68424387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08298
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05985
BRD-K73394628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52633
FOXA2	ENCODE Transcription Factor Targets	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10264401-41467_2023_Article_38238.pdf-50-TCF7_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Oral epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
acetyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
leukemic	GeneRIF Biological Term Annotations	1.0	null
lipomatous cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.103072
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mice	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
defense response	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41506
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48004
Th1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
ubiquitination	GeneRIF Biological Term Annotations	1.0	null
RSC-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26041
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14463
mefenamic acid-1863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.07732
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
lysine	GeneRIF Biological Term Annotations	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
being	GeneRIF Biological Term Annotations	1.0	null
trophoblasts	GeneRIF Biological Term Annotations	1.0	null
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.48376
negative regulation of cysteine-type endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SON_KD_GDS4448_35_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.199
basis	GeneRIF Biological Term Annotations	1.0	null
viral replication complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.609086
Fenretinide	CTD Gene-Chemical Interactions	1.0	null
stages	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04446
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40019
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.19601
BRD-K09450441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05501
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87396
BT16	DepMap CRISPR Gene Dependency	1.0	2.06826
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07573
Lung epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924091
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35836
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1927
BRD-K86086888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21325
DU-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.82
negative regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.341788
coordinate	GeneRIF Biological Term Annotations	1.0	null
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
celecoxib_homo sapiens_gpl8300_gds3384	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
melanoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78848
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30868
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.134
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.332
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
nfkappa	GeneRIF Biological Term Annotations	1.0	null
Dermal microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
Laryngeal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55173
SK-MEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21032
BRD-A52650764_Ingenol 3, 20-dibenzoate_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1607
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3022822-1471-2164-12-11-S10.XLS-Suppl_7_newLN229_SOX2_KO_MOCK_2-Unnamed_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
increased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
ISGF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.089
cdk1	GeneRIF Biological Term Annotations	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	2.17664
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947459
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846475
combination	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4719	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.157
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03199
P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537416
SMAD2	ChEA Transcription Factor Targets	1.0	null
PMC11955568-41467_2025_57429_MOESM9_ESM.xlsx-Data_S7-JUN_OIS_Martinez2020_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236647
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.894429
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.168
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BE-59-WG31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372258
non-small cell lung adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
linked	GeneRIF Biological Term Annotations	1.0	null
blocking	GeneRIF Biological Term Annotations	1.0	null
Chronic Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
trifluoperazine-2684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
selectivity	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40393
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31837
GTEX-XAJ8-0126-SM-47JYG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01686
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.85141
large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281776
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26324
naringenin-1342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Allergic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90046
Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62133
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838766
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
isoflupredone-1832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.133
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
positive regulation of tyrosine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
PMC2390572__F10	PFOCR Pathway Figure Associations 2023	1.0	null
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.09971
BA-29-OX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.565153
U178	CCLE Cell Line Gene Expression Profiles	1.0	1.37031
positive regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral Hemorrhage	CTD Gene-Disease Associations	1.0	1.09611
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18198
interleukin-5 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
Unipolar Depression	DisGeNET Gene-Disease Associations	1.0	null
mediators	GeneRIF Biological Term Annotations	1.0	null
Perturb_14318_KD_CEBPB_SRP270331	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
u266	HPA Cell Line Gene Expression Profiles	1.0	1.09754
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6947
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MDAMB231_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12635
exhibits	GeneRIF Biological Term Annotations	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852014
GSS	DepMap CRISPR Gene Dependency	1.0	2.66751
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.356314
nystatin-2500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10848
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01557
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57801
BRD-K75311902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29197
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12236
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.710449
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
negative regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
advanced	GeneRIF Biological Term Annotations	1.0	null
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37911
stabilization	GeneRIF Biological Term Annotations	1.0	null
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15921
tribenoside-2946	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
il20	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061339
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HG3	DepMap CRISPR Gene Dependency	1.0	3.11817
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
Filariasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74107
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.673
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05916
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
STAT4	ChEA Transcription Factor Targets	1.0	null
selectively	GeneRIF Biological Term Annotations	1.0	null
BRD-K15600710_S1057_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08451
NB-1691 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38554
AD-58-PW17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.257536
Viral protein interaction with cytokine and cytokine receptor	KEGG Pathways 2026	1.0	null
hsa-miR-4760-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.16859
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18368
Synovium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
Anemia	DisGeNET Gene-Phenotype Associations	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.506
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1779
ELK1	ChEA Transcription Factor Targets	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6695
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
scoulerine-1742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.68508
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57111
GSE139239_3_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
histological	GeneRIF Biological Term Annotations	1.0	null
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	1.35626
GE-40-GQ38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.913597
K5	GDSC Cell Line Gene Expression Profiles	1.0	2.0107
PMC5751286__F2	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K96379403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1168
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866099
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
radiation	GeneRIF Biological Term Annotations	1.0	null
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Metacercaria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
sulpiride-4389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K79965790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64872
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.94275
mecamylamine-3525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluid	GeneRIF Biological Term Annotations	1.0	null
confirm	GeneRIF Biological Term Annotations	1.0	null
BRD-K24950073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27451
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53434
CNTN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00397864
BRD-K02070226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54469
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
interface	GeneRIF Biological Term Annotations	1.0	null
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4647
well	GeneRIF Biological Term Annotations	1.0	null
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207978
vidarabine-2706	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348315
GUCY2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603011
BRD-A79316179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53424
increased hemoglobin content	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69136
Smc5-Smc6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.659482
BRD-K98089885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29237
danazol-1954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72883
Large cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217451
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37674
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43889
BRD-K42653521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17034
Perturb_12952_KO_ZFP36L2_SRP251843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.51715
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.002
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704355
jak1statactivating	GeneRIF Biological Term Annotations	1.0	null
b-lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223662
Hemolytic-Uremic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
BRD-K18768614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4432
LMNB2_02_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03171
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57441
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6489
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225229
Burkitt Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26485
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1626
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1375
GSE165689_0_v_1_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-47-IB34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.552864
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850739
trigger	GeneRIF Biological Term Annotations	1.0	null
RISC-loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
Sulindac	CTD Gene-Chemical Interactions	1.0	null
Phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.312
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.14071
PMC13127299-mmc2.xlsx-PBX1_kdRNAseq-hgnc_symbol_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
RCC10RGB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53211
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063206
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883983
Pancreatic Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
alexidine-7397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.923
layer 2 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06885
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08231
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
response to interleukin-4	GO Biological Process Annotations 2015	1.0	null
Leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.591
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892951
death	GeneRIF Biological Term Annotations	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78533
Cyclin E2-CDK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
17297461-Table2	GeneSigDB Published Gene Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
BRD-K62841603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40584
examination	GeneRIF Biological Term Annotations	1.0	null
ZB-33-MZ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.314235
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94787
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.35129
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34588
BRD-K22698363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21601
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
estradiol_homo sapiens_gpl571_gds4052	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17682054-Table1	GeneSigDB Published Gene Signatures	1.0	null
rko cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947459
col7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.842892
viomycin-2979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
colonic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
FB-33-LI31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.917889
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73721
TFAP2C	ChEA Transcription Factor Targets	1.0	null
Fever	CTD Gene-Disease Associations	1.0	1.03641
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8852
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828212
BRD-K54850621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07618
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55671
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158266
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35281
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78558
interactions	GeneRIF Biological Term Annotations	1.0	null
ROCK1_knockdown_156_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.40851
Bladder Urothelial Carcinoma_BLCA_TCGA-LC-A66R-01A-41R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39788
Buffy coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
beta-escin-2194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
reveals	GeneRIF Biological Term Annotations	1.0	null
Bullous Pemphigoid	DisGeNET Gene-Disease Associations	1.0	null
BRD-K64859133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11022
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58996
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09923
Tendon sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.474
Secondary motor area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02655
Glioblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
alpha-ergocryptine-3817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LTE2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4718	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DD-54-MA35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.486497
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79478
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.8936
regulation of cellular ketone metabolic process	GO Biological Process Annotations 2015	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
Esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2497
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29488
BRD-K39074860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97123
CRCGN016_MCF10A.TP53.M_24H:F09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31488
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09208
Stomach carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
PMC7537965__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955201
large cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190104
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_1162_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.17759
Perturb_5466_KD_WWTR1_SRP125175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.84588
tumors	GeneRIF Biological Term Annotations	1.0	null
BRD-K71755056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95827
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.429165
positive regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interferons	GeneRIF Biological Term Annotations	1.0	null
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86554
Refractory Cytopenia Of Childhood	DisGeNET Gene-Disease Associations	1.0	null
contribution	GeneRIF Biological Term Annotations	1.0	null
BRD-K44797874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06024
CB-02-XL81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247643
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.404184
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950353
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF217	ENCODE Transcription Factor Targets	1.0	null
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.41504
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19849
Fetal Death	CTD Gene-Disease Associations	1.0	1.13793
Perturb_15238_KD_TINCR_SRP082178	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.11056
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15282144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09304
BRD-K87516578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36013
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.412
Perturb_14152_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K46195730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45765
appears	GeneRIF Biological Term Annotations	1.0	null
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50293
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
Ring gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
PMC6895828__F4	PFOCR Pathway Figure Associations 2023	1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.01419
maturation	GeneRIF Biological Term Annotations	1.0	null
Chronic lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.18587
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.29229
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MA-43-MR37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331014
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	3.06306
suppressive	GeneRIF Biological Term Annotations	1.0	null
DE-69-QQ25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.587197
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47192
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-TPRX1_DOWN-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_down_from_an_FPKM_of_at_least_2_TPRX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K80483148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40986
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2421
MYC_01_237	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.38656
PMC7408575__F2	PFOCR Pathway Figure Associations 2024	1.0	null
16-HBE14o cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
ALDH9A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541388
SB-228357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0605
21NT	DepMap CRISPR Gene Dependency	1.0	3.41318
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
receptor binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858804
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85006
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61626
way	GeneRIF Biological Term Annotations	1.0	null
luteolin-3041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
whose	GeneRIF Biological Term Annotations	1.0	null
PMC10561055-mmc3.xlsx-LPS_T2-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Nausea	CTD Gene-Disease Associations	1.0	1.03827
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958215
more	GeneRIF Biological Term Annotations	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4211
designation	GeneRIF Biological Term Annotations	1.0	null
Planktonic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.58005
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41356
BRD-K00507184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25173
AD-30-VB23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390028
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73749
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01124
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.60238
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CRCGN009_HEPG2_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06304
PMC5611503__F9	PFOCR Pathway Figure Associations 2024	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49161
hs888lu	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.60189
Premature Coronary Artery Atherosclerosis	DisGeNET Gene-Phenotype Associations	1.0	null
terbutaline-1585	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDAN1_02_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.24793
pregnancy	GeneRIF Biological Term Annotations	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
QE-18-WG07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260567
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.228
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
bowel	GeneRIF Biological Term Annotations	1.0	null
PLC-PRF-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
Perturb_14153_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_182_KD_Slpi_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.2718
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49627
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.175
DC-17-ZB19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297753
AC-83-LN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207913
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
atovaquone-2480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0777
BRD-K58248315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8921
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eukaryotic translation initiation factor 2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
BRD-K88119862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31498
Perturb_198_KD_Asns_SRP119932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.0191
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K67390061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21901
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
diverse	GeneRIF Biological Term Annotations	1.0	null
PMC7583966__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2052	GDSC Cell Line Gene Expression Profiles	1.0	1.68118
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.495869
timolol-4685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_15223_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.22462
PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
been	GeneRIF Biological Term Annotations	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09368
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27713
Endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.74
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.750818
LY-294002-6195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
Interleukin-10, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864955
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
causal	GeneRIF Biological Term Annotations	1.0	null
mmp29	GeneRIF Biological Term Annotations	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233162
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10157
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Choriodecidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
molecular_function	GO Molecular Function Annotations 2015	1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06485
BRD-K91145395_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.951196
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60034
sitedirected	GeneRIF Biological Term Annotations	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-2.05145
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7706
Atrophy	CTD Gene-Disease Associations	1.0	1.63698
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478145
transcriptional	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C6-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
BC-51-ME52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308324
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34535
Uveal coloboma-cleft lip and palate-intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Kindler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077999
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77052
pre-malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
UC-80-UO92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.539927
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26331
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1545
bmediated	GeneRIF Biological Term Annotations	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
active	GeneRIF Biological Term Annotations	1.0	null
oxyphenbutazone-6160	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879964
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831403
decreasing	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
targets	GeneRIF Biological Term Annotations	1.0	null
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54132860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30367
Cyclosporine	CTD Gene-Chemical Interactions	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nocodazole-7145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75496
Perturb_15568_KD_ATF6_SRP364933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26972
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.56425
zardaverine-2926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Splenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07166
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.2691
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
resistance	GeneRIF Biological Term Annotations	1.0	null
Perturb_12240_KD_CHD4_SRP190500	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.68321
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87309
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02234
Cholinergic urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
novo	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.12647
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00605
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.393226
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.76412
pivmecillinam-7312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JAK-STAT signaling pathway	KEGG Pathways 2026	1.0	null
PMC3742913__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16227
HMV-II	GDSC Cell Line Gene Expression Profiles	1.0	2.41037
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04801
Embryo Loss	CTD Gene-Disease Associations	1.0	1.21567
BRD-K27417269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23854
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71621
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1968
Heart Diseases	CTD Gene-Disease Associations	1.0	1.4612
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12756
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18655
18794137-SuppTable1d	GeneSigDB Published Gene Signatures	1.0	null
Spontaneous Abortion	DisGeNET Gene-Phenotype Associations	1.0	null
mRNA_TUBA1A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
own	GeneRIF Biological Term Annotations	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1764
ATF3-23680149-GBM1-GSC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64385
VA-92-QP54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.369736
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
mrc-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92004
BCPAP	GDSC Cell Line Gene Expression Profiles	1.0	1.47999
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67326
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11783
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069529
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18862
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02994
BRD-K82839033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06671
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.22451
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13473
Perturb_178_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.3093
Painful Bladder Syndrome	DisGeNET Gene-Disease Associations	1.0	null
increased hemoglobin content	IMPC Knockout Mouse Phenotypes	1.0	null
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
melanoma	GeneRIF Biological Term Annotations	1.0	null
Perturb_694_KD_SREBP2_SRP064735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.19695
BRD-K63758740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1844
connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
positive regulation of jak-stat cascade	GO Biological Process Annotations 2015	1.0	null
mda7	GeneRIF Biological Term Annotations	1.0	null
STING complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40158
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
CF-42-OS28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275026
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-delta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905137
hep3b	GeneRIF Biological Term Annotations	1.0	null
Perturb_12234_KD_STAT3_SRP081918	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_688_KD_ASAP2_SRP406127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K32078195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36775
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
survival	GeneRIF Biological Term Annotations	1.0	null
PPARD-23176727-KERATINOCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
increased circulating sodium level	IMPC Knockout Mouse Phenotypes	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21097
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57522
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86084
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
Perturb_12931_KO_KAT7_SRP212620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.94796
Childhood Leukemia	DisGeNET Gene-Disease Associations	1.0	null
dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38453
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.664775
H3K23ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Bronchial epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04156
BRD-K93008833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07701
BRD-K49847771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83591
PMC9619093__F2	PFOCR Pathway Figure Associations 2024	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01851
ATR_KD_GSE54268_664_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.203
m8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
BRD-K19800225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18439
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94Y-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
gadd45alpha	GeneRIF Biological Term Annotations	1.0	null
Ovary cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.411
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
BRD-A56592690_PX12_NOMO1_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_12895_KO_NCOR1_SRP319377	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.83935
Seizures	CTD Gene-Disease Associations	1.0	1.173
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18227
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981672
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41063
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5747
BRD-K16929626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63159
BRD-K51654114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3022
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.584
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
selective	GeneRIF Biological Term Annotations	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
breast	GeneRIF Biological Term Annotations	1.0	null
Perturb_12268_KO_CECR1_SRP255026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.55106
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
Dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.811
BRD-K73681382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33201
migration	GeneRIF Biological Term Annotations	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ajmaline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5034
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27876
Measles	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69294
smooth	GeneRIF Biological Term Annotations	1.0	null
BRD-K18084996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45677
PMC6298946__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Ire1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.262
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.62153
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4865
CHK1_KD_GSE54268_666_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
azacitidine-4010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pimozide-1562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
athymic	GeneRIF Biological Term Annotations	1.0	null
2-hydroxymethyl-4,8-dihydrobenzo(1,2-b-5,4-b')dithiophene-48-dione	CTD Gene-Chemical Interactions	1.0	null
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16916
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00504
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_339_KD_EIF4A1_SRP072285	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
pramocaine-3811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135842_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206767
Bronchogenic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.62
Perturb_2456_KD_RNF181_SRP243458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.39566
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10308
ATM_01_219	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.65306
Colonic epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
hsa-miR-4274	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
quinpirole-2977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-01-FB85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366115
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
KE39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44622
BRD-K11188962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64656
trifluoperazine-1165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Attachment organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
provide	GeneRIF Biological Term Annotations	1.0	null
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung Injury	CTD Gene-Disease Associations	1.0	1.14268
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901996
activating	GeneRIF Biological Term Annotations	1.0	null
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.517362
Fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03912
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.163641
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
properties	GeneRIF Biological Term Annotations	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.789
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
BRD-K75495990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07454
BRD-K40222892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0111
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K12043227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12981
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.657167
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.6636
Psoriatic arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
antigen	GeneRIF Biological Term Annotations	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.980263
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70747
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4484_OE_Msi2_SRP067535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.98284
LNCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
T-cell non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Lower gum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98776
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03055
supporting	GeneRIF Biological Term Annotations	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51527
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
Cytokine-cytokine receptor interaction	KEGG Pathways 2026	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_FEM1B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
prochlorperazine-4439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
15958547-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
il19	GeneRIF Biological Term Annotations	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11979991-mmc1.xlsx-13_AP1-E2F_targets_Cycl-Quies-Gene_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8776082__F1	PFOCR Pathway Figure Associations 2024	1.0	null
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13473
lymphatic	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34652
buspirone-1282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
15492251-Table1	GeneSigDB Published Gene Signatures	1.0	null
endoplasmic	GeneRIF Biological Term Annotations	1.0	null
Prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.996
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04872
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Melioidosis	DisGeNET Gene-Disease Associations	1.0	null
6-bromoindirubin-3'-oxime-7048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932489
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.454725
hsa-miR-140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84058
COLO-679	GDSC Cell Line Gene Expression Profiles	1.0	1.74739
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7109
conditions	GeneRIF Biological Term Annotations	1.0	null
BRD-A50913845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87919
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Esophageal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Large cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
GSE111247_14_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.98394
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52383
BL70	DepMap CRISPR Gene Dependency	1.0	4.30768
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34705
plasma	GeneRIF Biological Term Annotations	1.0	null
PMC5709591__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
vsmc	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9212
Pancreatic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
17297478-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
cc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.515
safe	GeneRIF Biological Term Annotations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.601066
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
tgase4	GeneRIF Biological Term Annotations	1.0	null
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
A-375 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.610448
bcell	GeneRIF Biological Term Annotations	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT483	CCLE Cell Line Gene CNV Profiles	1.0	1.43745
gadd	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.334356
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841083
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
du-145 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.513743
Trunk kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
S0-EE-YMWJ_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433907
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2043
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Mammary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PF-59-CY33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.856641
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
manner	GeneRIF Biological Term Annotations	1.0	null
sirolimus-1183	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
secreted	GeneRIF Biological Term Annotations	1.0	null
Perturb_171_KD_Asns_SRP119931	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70097
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946404
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320227
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20951
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02773
hsa-miR-4493	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
strongly	GeneRIF Biological Term Annotations	1.0	null
regulate	GeneRIF Biological Term Annotations	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.39338
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946404
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63496
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835388
PMC10638041-mmc1.docx-0-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Neoplasms, Experimental	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85114
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
PC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.597
lead	GeneRIF Biological Term Annotations	1.0	null
lisuride-1962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Advanced Melanoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43056
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850491
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
suppressor	GeneRIF Biological Term Annotations	1.0	null
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
BRD-K46149271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05287
DC-23-UM36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.695575
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25263
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19603900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03794
FLI1_01_15	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	8.12403
hela	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846801
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.27
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
Infertility, Female	CTD Gene-Disease Associations	1.0	1.28058
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08601
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980537
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.57214
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55173
report	GeneRIF Biological Term Annotations	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970894
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87323
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01287
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tonsil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
ipc298	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
BRD-K03287885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07682
caaac	GeneRIF Biological Term Annotations	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
effects	GeneRIF Biological Term Annotations	1.0	null
MAX_02_192	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.9542
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
carbenoxolone-3353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE249404_0_v_1_oxytocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
sirolimus-1162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.267
Hypersensitivity	CTD Gene-Disease Associations	1.0	1.02671
Intestinal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
Rheumatoid arthritis disease specific synovial fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
serine-type peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.333
CRCGN012_HEPG2_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15081
PMC6487024-13148_2019_658_MOESM2_ESM.xlsx-S10-Pr_intrc_ADNP-1-Unnamed_1_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
Vomiting	CTD Gene-Disease Associations	1.0	1.2895
cisplatin_homo sapiens_gpl6883_gse47980	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	2.52651
trimester	GeneRIF Biological Term Annotations	1.0	null
PMC3382204__F5	PFOCR Pathway Figure Associations 2024	1.0	null
prostate gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
HOXA10_01_358	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.73752
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10351
Lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12635
glycosylation	GeneRIF Biological Term Annotations	1.0	null
gamma	GeneRIF Biological Term Annotations	1.0	null
mammary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.536684
sensitizes	GeneRIF Biological Term Annotations	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
subepithelial	GeneRIF Biological Term Annotations	1.0	null
tight	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.573
rtg2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Neoplasms	CTD Gene-Disease Associations	1.0	1.89169
HUNS1	DepMap CRISPR Gene Dependency	1.0	3.92986
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt	CTD Gene-Chemical Interactions	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.83197
PMC9314667-Table_1.xlsx-Regulons-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11331752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93093
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
MXI1	ENCODE Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
Perturb_9727_KD_SF3B1_SRP337858	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hsa-miR-601	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
justify	GeneRIF Biological Term Annotations	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97795
ionizing	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
il20r1il20r2	GeneRIF Biological Term Annotations	1.0	null
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43215
Alveolar Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
cicloheximide-2723	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
stage	GeneRIF Biological Term Annotations	1.0	null
interleukin24	GeneRIF Biological Term Annotations	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Conjunctival disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2294
RAD21	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53168
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clozapine-1170	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
killing	GeneRIF Biological Term Annotations	1.0	null
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2063
GSE157635_1_v_0_trem2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503481
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41243
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420004
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9686
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30466
BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
PMC12783836-41398_2025_3738_MOESM3_ESM.xlsx-Table_S5-Table_S5_Pleiotropy_assessment_for_the_significant_results_of_forward_MR_analyses_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
overexpression	GeneRIF Biological Term Annotations	1.0	null
UD-07-US73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.984049
CRCGN015_MCF10A.WT.HP_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19876
ligandreceptor	GeneRIF Biological Term Annotations	1.0	null
BRD-K98189856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68675
Rectum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246649
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385896
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31189
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
indicates	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43233
12734205-TableS2	GeneSigDB Published Gene Signatures	1.0	null
sh-sy5y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250627
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.36715
HS944T	CCLE Cell Line Gene Expression Profiles	1.0	1.84043
Psoriasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nsclc	GeneRIF Biological Term Annotations	1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.19788
thus	GeneRIF Biological Term Annotations	1.0	null
igr37	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12964
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223593
IgM immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.703
pancreatitis	GeneRIF Biological Term Annotations	1.0	null
autocrineparacrine	GeneRIF Biological Term Annotations	1.0	null
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DJ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
wide	GeneRIF Biological Term Annotations	1.0	null
acute myeloid leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10003
differentiationinducing	GeneRIF Biological Term Annotations	1.0	null
20460173-ImmPortInterleukins	GeneSigDB Published Gene Signatures	1.0	null
BRD-K53993775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22744
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929315
PMC6039466-41598_2018_28739_MOESM1_ESM.docx-3-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
driving	GeneRIF Biological Term Annotations	1.0	null
BD-38-QC39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.34719
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K26214026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11599
SKMEL24	CCLE Cell Line Gene Expression Profiles	1.0	1.51046
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.234
Squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04874
BRD-K91944762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22832
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00063
Peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
ccl2mcp1	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04181
PGR_01_188	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.78182
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82882
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895455
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.074
TBP	ENCODE Transcription Factor Targets	1.0	null
PMC12436147-41380_2025_3032_MOESM1_ESM.xlsx-ST2-Supplementary_Table2_Blood_pQTLs_that_were_selected_as_genetic_instruments_for_MR_analyses_UKB_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CCR5	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.787
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21554
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10085
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
DA-10-GX45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.505844
CAV3_KO_GDS3533_357_mouse_mammalian glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
produce	GeneRIF Biological Term Annotations	1.0	null
Nasal lavage fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88645
BRD-A16119053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10287
todralazine-5087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spectrum	GeneRIF Biological Term Annotations	1.0	null
Kidney Failure, Acute	DisGeNET Gene-Disease Associations	1.0	null
AF-41-QY60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.696126
BRD-K96817767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17884
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62212
BRD-A52650764_Ingenol 3, 20-dibenzoate_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06119
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
lymphnode_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.910075
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61535
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09668
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75495
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC3500769-srep00875-s3.xls-AP1-Time_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71406
18849563-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
rHypoE-22 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061887
H-1299	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
BC-80-FK74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256074
serine phosphorylation of stat3 protein	GO Biological Process Annotations 2015	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980537
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cvc7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
PMC12422825-aging-17-8-206293-s003.xlsx-i_MR_IP-Unnamed_5_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.32577
PMC7498011__F5	PFOCR Pathway Figure Associations 2023	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.56747
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
overcomes	GeneRIF Biological Term Annotations	1.0	null
18277965-Table4a	GeneSigDB Published Gene Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06557
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.611
stachydrine-1751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Measles Chicago-1_24Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.89032
Mammary-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.738554
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.47435
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3701
Respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
CHD2	ENCODE Transcription Factor Targets	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
11-deoxy-16,16-dimethylprostaglandin E2-7519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
increased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39217
thioridazine-2690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SCABER	CCLE Cell Line Gene Expression Profiles	1.0	1.69036
interference	GeneRIF Biological Term Annotations	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Lung Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23429
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938299
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863206
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62261
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13752
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
fatty-acyl-CoA synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16787_KD_ETS1_SRP131807	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.699
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87402
Lung cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.872
Esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62084
laryngeal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.563637
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.465214
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37911
progesterone-2426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33245
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24826
nhej	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34974
Chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826013
BRD-K81206010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11333
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911313
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45563
5g3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
BRD-K02106348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21497
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16183
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
18178870-Table2	GeneSigDB Published Gene Signatures	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08876
fluorocurarine-6083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K91410469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15798
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03667
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6686
BRD-K91423144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27307
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04933
classical	GeneRIF Biological Term Annotations	1.0	null
oxantel-6738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
repair	GeneRIF Biological Term Annotations	1.0	null
ciclosporin-1331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
chronicity	GeneRIF Biological Term Annotations	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873027
Lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.49665
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0011
caski cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301758
contributes	GeneRIF Biological Term Annotations	1.0	null
inducing	GeneRIF Biological Term Annotations	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44084
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.44217
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
harmol-1750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monocyte-derived dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975824
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.201
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214363
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0545
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.88659
endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
S100A8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.009
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47835
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73502
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10157
MAOA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517216
Perturb_13727_KD_SH3PXD2AAS1_SRP330559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
EZH2	ENCODE Transcription Factor Targets	1.0	null
non-small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
PMC2390572__F10	PFOCR Pathway Figure Associations 2024	1.0	null
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835596
Helper T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.082
prednicarbate-5119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85685
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.5094
496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80896
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387794
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11025
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC9374760__F3	PFOCR Pathway Figure Associations 2024	1.0	null
SR-95531-1316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6837
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
jnk13	GeneRIF Biological Term Annotations	1.0	null
BRD-K58245454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57196
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13516
however	GeneRIF Biological Term Annotations	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15482_OE|KD_ERG|EWSR1_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4026
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.410597
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02175
STAT3	ENCODE Transcription Factor Targets	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24208
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
dizocilpine-2069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE139239_1_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3249
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.651573
p53	GeneRIF Biological Term Annotations	1.0	null
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25354
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
multidrug	GeneRIF Biological Term Annotations	1.0	null
STAT6-20620947-CD4_POS_T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXA1_01_110	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.02771
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03844
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Interleukin-10/19/20/24/26 family	InterPro Predicted Protein Domain Annotations	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77669
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063246
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.94655
perk	GeneRIF Biological Term Annotations	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512564
constitute	GeneRIF Biological Term Annotations	1.0	null
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PD-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-23-TZ42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378728
JUN	ENCODE Transcription Factor Targets	1.0	null
pathways	GeneRIF Biological Term Annotations	1.0	null
under	GeneRIF Biological Term Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988948
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887611
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.741725
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63957636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09819
PMC11474168-ccr-23-1242_supplementary_table_s4_suppst4.xlsx-AR_tumors_genes-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancers	GeneRIF Biological Term Annotations	1.0	null
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34751
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
thioridazine-4454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-58-PW17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.827953
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20171
Perturb_8419_KD_NME7_SRP304271	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
Periodontitis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bullous pemphigoid	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
jnk	GeneRIF Biological Term Annotations	1.0	null
Keloid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.369
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847911
PMC7569567__F2	PFOCR Pathway Figure Associations 2024	1.0	null
TCF7L2_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10580455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48354
0173570-0000-7389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18123
BRD-K29120026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16617
BRD-K58933168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56256
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.38478
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53075
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.693187
MRK-NU-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994135
Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K80098154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43276
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
downregulation	GeneRIF Biological Term Annotations	1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389134
OB-65-AI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267452
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
positive regulation of peptidyl-tyrosine phosphorylation	GO Biological Process Annotations 2015	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25174
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14865
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861464
dna	GeneRIF Biological Term Annotations	1.0	null
increases	GeneRIF Biological Term Annotations	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.89723
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282983
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13588
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08724
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08781
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90955
SLAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
ivermectin-7206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4751
Mammary Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.35386
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.05089
Endoplasmic reticulum-Golgi intermediate compartment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Infertility, Male	CTD Gene-Disease Associations	1.0	1.48582
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
induces	GeneRIF Biological Term Annotations	1.0	null
clu	GeneRIF Biological Term Annotations	1.0	null
regulation of cysteine-type endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
proteasome-associated autoinflammatory syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
CD274	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00660388
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982199
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
18270326-Table1	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_711_KO_DNMT3B_SRP389363	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.05813
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076355
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24426
Mixed Lineage Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
buflomedil-1338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9721
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406385
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08193
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052359
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49195
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K77547131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63676
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5687
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.027384
Systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC5670203-41467_2017_1251_MOESM5_ESM.xlsx-differential_expressed_BCL6_tar-gene_id_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26357
LP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88079
hematopoietic	GeneRIF Biological Term Annotations	1.0	null
fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56257
Memory Disorders	CTD Gene-Disease Associations	1.0	1.20295
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57958
GSE102187_0_v_1_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NC-27-AD53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.222929
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.265
PMC7076804__F5	PFOCR Pathway Figure Associations 2024	1.0	null
KC-32-GO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.834258
Chronic asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
Secondary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
C8166	DepMap CRISPR Gene Dependency	1.0	3.31548
ABCC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053885
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891829
myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.261952
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.725835
effectively	GeneRIF Biological Term Annotations	1.0	null
TE-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.907574
YD38	CCLE Cell Line Gene Expression Profiles	1.0	1.75452
fludroxycortide-7378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17523
BRD-K50580743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29356
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962997
counterparts	GeneRIF Biological Term Annotations	1.0	null
Decidual stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A02481876_Importazole_HA1E_24.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNA15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0041191
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8478
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52855
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.16169
Cytotoxic T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.841
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05014
Perturb_4592_KD_EBNA1_SRP064652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.12959
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.04813
Perturb_6540_KO_XIST_SRP301287	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.60602
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
ATM_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60460300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63498
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A3L1-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32875
higher	GeneRIF Biological Term Annotations	1.0	null
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.220371
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
hemolytic-uremic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
ability	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28167
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.624
investigated	GeneRIF Biological Term Annotations	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00631
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47035
Dermatographia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226766
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21874
Colorectal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25938
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.044
CE-20-VA70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.376884
mir203	GeneRIF Biological Term Annotations	1.0	null
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83506
immune	GAD High Level Gene-Disease Associations	1.0	0.295739
thereby	GeneRIF Biological Term Annotations	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.336
expressing	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	Pathway Commons Protein-Protein Interactions	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24841
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7630-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4489805-pone.0132249.s008.xls-STAT1_T_cell_activation-Supplementary_Table_4_SDEG_involved_in_STAT-1_mediated_T_cell_activation_network_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35963610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97353
proteasome	GeneRIF Biological Term Annotations	1.0	null
AA-52-JS03_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.55407
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16800391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25533
adenocarcinoma	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_540_OE_EWS/FLI_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.066
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I1-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73558
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.4047
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0979
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
testosterone-5271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
17297478-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-1972	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
GSE96641_5_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM1	ENCODE Transcription Factor Targets	1.0	null
tomatidine-1754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hiv Infections	DisGeNET Gene-Disease Associations	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70323
Retinoblastoma	DisGeNET Gene-Disease Associations	1.0	null
PMC10808687-Table_1.xlsx-Supplementary_Table_9-Supplementary_Table_9_Replication_MR_analysis_results_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SmoothMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
depends	GeneRIF Biological Term Annotations	1.0	null
Perturb_15046_OE_FOXQ1_SRP319582	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.2419
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35533
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
Myeloid Leukemia	DisGeNET Gene-Disease Associations	1.0	null
regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
BRD-K66538269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39197
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08205
IgE immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.142
Hyperimmunoglobulin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
guanabenz-5703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
current	GeneRIF Biological Term Annotations	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32663
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
within	GeneRIF Biological Term Annotations	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
binding	GO Molecular Function Annotations 2015	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.481263
intermediate stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17719
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40469
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9597993__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC6352980__F2	PFOCR Pathway Figure Associations 2024	1.0	null
KLF15_Deficiency_GDS2687_649_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
sulfachlorpyridazine-4326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
keratinocyte	GeneRIF Biological Term Annotations	1.0	null
3,3',4,5'-tetrahydroxystilbene	CTD Gene-Chemical Interactions	1.0	null
investigate	GeneRIF Biological Term Annotations	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13252
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09639
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
correlations	GeneRIF Biological Term Annotations	1.0	null
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183453
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25735
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
preferentially	GeneRIF Biological Term Annotations	1.0	null
BRD-K20138377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58097
acute	GeneRIF Biological Term Annotations	1.0	null
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.333124
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
CP-690334-01-3826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7565
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09673
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25131
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16974
significant	GeneRIF Biological Term Annotations	1.0	null
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55393
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1721
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.96727
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.7071
skin	GeneRIF Biological Term Annotations	1.0	null
PMC8010670-Table_7.XLSX-LPS_3_Genes-CCL3L1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hexestrol-5776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.57498
review	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
anisomycin-1304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.558
cellular process	GO Biological Process Annotations 2015	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42883
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.22243
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14149_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MDA-MB-453 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
keratinocytes	GeneRIF Biological Term Annotations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0776
20460173-ImmPortCytokines	GeneSigDB Published Gene Signatures	1.0	null
diflorasone-4077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
P3H3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540887
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56999
negative regulation of cellular component movement	GO Biological Process Annotations 2015	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881987
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
BRD-K82571240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78235
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
alclometasone-6094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82909038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06153
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51778
CB-73-HZ47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.54251
PMC8923803__F9	PFOCR Pathway Figure Associations 2024	1.0	null
response to cytokine	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211689
betulinic acid-1345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
BRD-K99252563_QL-XII-47_HS578T_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
m2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06176
Pulmonary Fibrosis	CTD Gene-Disease Associations	1.0	1.36247
jakstat	GeneRIF Biological Term Annotations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42807
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.547
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208193
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85474
Weight Gain	CTD Gene-Disease Associations	1.0	1.42967
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WP-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRIK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00529632
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.168
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887484
burkitt lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102482
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.47
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3856
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955482
laryngeal benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.67551
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lymphopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.63
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.1313
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18326
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.366944
PK 11195	CTD Gene-Chemical Interactions	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_177_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.97903
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0285
BRD-K76251351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15088
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41229
Perturb_12299_KD_METTL3_ERP137121	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.05084
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15052303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11478
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
gbm	GeneRIF Biological Term Annotations	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Facial hemiatrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
bronchus	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.001
epidermis	GeneRIF Biological Term Annotations	1.0	null
BB-87-SF89_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283553
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854129
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07305
Nasopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41641
HDQP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66458
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27816
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8256365-JCMM-25-6373-s003.xlsx-ONECUT1_KEGG_JAK_STAT_SIGNALING-PROBE_ONECUT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25838
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67124
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
il2activated	GeneRIF Biological Term Annotations	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0008
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.64958
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917032
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308974
BRD-K30989303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2685
enhances	GeneRIF Biological Term Annotations	1.0	null
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
BRD-K56120807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88594
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-D_eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04779
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
IgG immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.663
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40879
HCC1359	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947459
BRD-K93195567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15255
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
metoclopramide-4285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918431
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
B16-F10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
TPD52L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00443623
BRD-A53381587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08536
intracellular part	GO Cellular Component Annotations 2015	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.958
BRD-K72161690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26713
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01208
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64268
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4111
BRD-K20245846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17358
positive regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3959
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068136
adenoviral	GeneRIF Biological Term Annotations	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29732
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.429333
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26213
KA-63-FH23_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259004
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951541
inflammatory response	GO Biological Process Annotations 2015	1.0	null
negative regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
various	GeneRIF Biological Term Annotations	1.0	null
BRD-K14327064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79566
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
mexican	GeneRIF Biological Term Annotations	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309697
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.86874
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73667
BRD-K50829918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56323
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
mdamb157	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
Perturb_14151_KD_RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.5051
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00613
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1053
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47537
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395783
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.844424
regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22528
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39591
Gastric epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22489
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interleukin-1 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
PMC4904359-12915_2016_267_MOESM12_ESM.xlsx-ARGFX_UP-All_significantly_up_regulated_genes_determined_by_DESeq2_fold_change_greater_than_1_25_going_up_to_an_FPKM_of_at_least_2_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94275706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32265
betacatenin	GeneRIF Biological Term Annotations	1.0	null
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6831824-mmc7.csv--IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31758107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70535
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1278
BRD-K04568082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34755
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03945
NCIH660	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60704
regulation of protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
etilefrine-2930	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60997369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14231
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
PMC9192598__F3	PFOCR Pathway Figure Associations 2024	1.0	null
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209792
CHK2_KD_GSE54268_667_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.50689
spleen	HPA Tissue Gene Expression Profiles	1.0	1.07547
mephenesin-7374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Melanoma	CTD Gene-Disease Associations	1.0	1.19014
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09992
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
BRD-K12710356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97563
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40466
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
BRD-K53757555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35735
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
prostate gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00458
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072127
Nucleus of the solitary tract, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06384
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
secondary	GeneRIF Biological Term Annotations	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3248
furthermore	GeneRIF Biological Term Annotations	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.48601
positive regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
fulvestrant-1146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_1371_KD_IGF2BP2_SRP252209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.11287
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VEGF-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.832
correlated	GeneRIF Biological Term Annotations	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4159
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2777
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.460869
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-A02481876_Importazole_HA1E_6.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
theobromine-6613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
stimulated	GeneRIF Biological Term Annotations	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884336
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S0-EE-XKW4_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248368
BRD-K25718630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24273
PMC8108288-gutjnl-2020-321731supp004.xlsx-LPS_stimulation-gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
programmed cell death	GO Biological Process Annotations 2015	1.0	null
AD-58-PW17_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319739
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.874457
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Perturb_15562_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63151
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.471
Perturb_4262_KD_TRASH_SRP361857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
OB-77-XJ02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22487
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943753
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35708
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39595
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.713409
Four-helical cytokine-like, core	InterPro Predicted Protein Domain Annotations	1.0	null
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.0843
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.33489
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3648
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
QA-34-PH05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.945096
induced	GeneRIF Biological Term Annotations	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.41206
BRD-K18332967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10618
Perturb_17201_OE_GATA3|JUN_SRP188712	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.98441
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
r9ab	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056184
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.498
minimal	GeneRIF Biological Term Annotations	1.0	null
QE-00-EB96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.318111
BRD-A36630025_-666_PC3_24.0_h_0.35_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
primary	GeneRIF Biological Term Annotations	1.0	null
Severe combined immunodeficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.582989
DA-10-GX45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.21299
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
il24induced	GeneRIF Biological Term Annotations	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Granulocyte macrophage colony-stimulating factor receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
gk1.5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Eosinophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
tetracycline-5757	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-23-PM31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20654
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870044
Persistent Oligoarticular Juvenile Idiopathic Arthritis	DisGeNET Gene-Disease Associations	1.0	null
inflammatory	GeneRIF Biological Term Annotations	1.0	null
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.44282
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased	GeneRIF Biological Term Annotations	1.0	null
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26459891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05706
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
trichostatin A-4237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.567997
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
Dyslipidemias	CTD Gene-Disease Associations	1.0	1.01174
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12286
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
CORL47	DepMap CRISPR Gene Dependency	1.0	6.01138
MAPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437791
BRD-K89377615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01634
allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.904978
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01382
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Filarial elephantiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	0.997566
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16654
Prostate gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.984
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
changes	GeneRIF Biological Term Annotations	1.0	null
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00385464
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923957
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31052
17952126-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.876
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
suloctidil-1297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846782
regulation of cellular amino acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.33025
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15203
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_8768_OE_lncSLC4A11_SRP167170	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.70848
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.875
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40409
BRD-K04628654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16624
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11452
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
Solid Neoplasm	DisGeNET Gene-Phenotype Associations	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18184
interleukin10	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
b84	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
PRDM1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	3.15304
tdependent	GeneRIF Biological Term Annotations	1.0	null
BRD-K54533560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31251
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9371
invasive	GeneRIF Biological Term Annotations	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Growth factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51444
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059941
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263763
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00903
RKN	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35219
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.26483
glioma	GeneRIF Biological Term Annotations	1.0	null
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943314
BB-86-BE39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.505201
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90465
effective	GeneRIF Biological Term Annotations	1.0	null
YA-44-LW45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.330935
Perturb_2821_KD_Src_SRP194728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K85606544_neratinib_SKBR3_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-WK-A8XX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inducible	GeneRIF Biological Term Annotations	1.0	null
ESR1-20056654-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
delivered	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.624
BRD-K18117162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07016
Eye Diseases	CTD Gene-Disease Associations	1.0	1.18718
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216379
BRD-K08576275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39282
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120845
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.851992
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00863
Autoimmune Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
periodontitis	GeneRIF Biological Term Annotations	1.0	null
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046408
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73974
HO-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.41084
negative regulation of cell migration	GO Biological Process Annotations 2015	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983227
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4807
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.82779
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BE-42-IC00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.08614
Q fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cb95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209744
KMRC1	DepMap CRISPR Gene Dependency	1.0	2.01915
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05729
cellular response to biotic stimulus	GO Biological Process Annotations 2015	1.0	null
diethylstilbestrol-4547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91617
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881997
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6691
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93349
Cytokine cytokine receptor interaction	WikiPathways Pathways 2024	1.0	null
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16347
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_3835_KD_RNPK_SRP342664	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
versions	GeneRIF Biological Term Annotations	1.0	null
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.41677
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7109
Interleukin-24	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE179002_0_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.773383
Tetrachlorodibenzodioxin	CTD Gene-Chemical Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30236
Periodontal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
mast	GeneRIF Biological Term Annotations	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
adenovirus	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5556
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912394
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51667
chronic	GeneRIF Biological Term Annotations	1.0	null
LIN28A_01_215	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.25587
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.04941
Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47103
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
TFAP2C-20629094-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
drug	GeneRIF Biological Term Annotations	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-2054	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28395
CELF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479962
Perturb_3419_KO_USP7_SRP330182	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K27265817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49259
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
Alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32114
BRD-K04454173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18755
PMC10901932-10528_2023_10379_MOESM1_ESM.docx-0-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
nilutamide-6763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clusterin	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9297
behavior	GeneRIF Biological Term Annotations	1.0	null
Prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.879
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16259
Gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Hepa-1c1c7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39129
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53598
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07567
clioquinol-3084	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prochlorperazine-1215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.64985
gstmda7	GeneRIF Biological Term Annotations	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82764
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.7098
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5761
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11399565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3155
mv4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535833
Carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.334
Perturb_200_OE_Mir204_SRP131517	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40121
response to molecule of bacterial origin	GO Biological Process Annotations 2015	1.0	null
positive regulation of protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K02526760_QS 11_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
mRNA_ATF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
peptidyl-serine phosphorylation	GO Biological Process Annotations 2015	1.0	null
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
dobutamine-1589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
degraded	GeneRIF Biological Term Annotations	1.0	null
rheumatoid	GeneRIF Biological Term Annotations	1.0	null
sari	GeneRIF Biological Term Annotations	1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38834
p53independent	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.189
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CB-24-AT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327872
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41294
PNT-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41525
NCI-H1838	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65193
Perturb_5311_KD_NFATC3_SRP275579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21905
hsa-miR-381	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Gamma delta T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.6556
synovial	GeneRIF Biological Term Annotations	1.0	null
Liver And Intrahepatic Biliary Tract Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
DA-10-VU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397465
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874218
MRPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65165
Prostate adenocarcinoma_PRAD_TCGA-J4-A6G1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7499
AD-18-XC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286604
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.96285
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58104
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6335
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53094498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22272
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.30881
Perturb_18442_KD_YAP1/WWTR1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35537
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.10349
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56702
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS852T	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.730946
PMC12783836-41398_2025_3738_MOESM3_ESM.xlsx-Table_S2-Table_S2_Causalities_in_the_forward_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Ovarian Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
fh142	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
identify	GeneRIF Biological Term Annotations	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052425
M cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402523
Periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25862
BRD-K13715646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24715
18427120-DataS4	GeneSigDB Published Gene Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21912
Perturb_4012_KD_AHR_SRP262152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875481
modulates	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490229
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
hetorodimeric	GeneRIF Biological Term Annotations	1.0	null
Glioblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08325
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.676
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05618
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065906
interleukin-13 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12618_KD_SREBF2_SRP281894	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
monobenzone-3054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
geldanamycin	CTD Gene-Chemical Interactions	1.0	null
Preosteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985977
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Adult Diffuse Large B-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.183
belonging	GeneRIF Biological Term Annotations	1.0	null
mediated	GeneRIF Biological Term Annotations	1.0	null
mesoridazine-1725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
leading	GeneRIF Biological Term Annotations	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7634
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063206
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070241
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3432
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
intercalate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12431
Hypereosinophilic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
BRD-K97842654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08037
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.151
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.864577
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66472
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC5611503__F9	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K07307589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32878
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098983
AD-86-OB87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375178
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.79275
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.81665
Juvenile rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925955
Perturb_2874_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TCF4-18268006-LS174T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
regulation of locomotion	GO Biological Process Annotations 2015	1.0	null
Pulmonary tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78533
HSC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.50012
turn	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
biological_process	GO Biological Process Annotations 2015	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36851
gacaccggaa	GeneRIF Biological Term Annotations	1.0	null
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32458
HS675T	CCLE Cell Line Gene Expression Profiles	1.0	1.43285
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.249356
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YBX1_01_256	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.97736
SK-N-AS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
CaSki cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
GSE232261,GSE232263_0_v_1_usf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79402882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04932
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2294
antitumor	GeneRIF Biological Term Annotations	1.0	null
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02579
PMC11125956__F8	PFOCR Pathway Figure Associations 2024	1.0	null
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45833502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20705
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37056
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
clioquinol-4663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945384
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
PMC3500769-srep00875-s3.xls-FOXA1-Time_24_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.07022
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37019
thioridazine-1905	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72474
COLO-678	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IgE B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637594
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898852
melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27785
hapt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
chemosensitivity	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.968
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285422
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
presence	GeneRIF Biological Term Annotations	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40235
Plant gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.60733
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0826
Perturb_756_KO_DNMT1_SRP389363	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.57143
Naive T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.664
CD95 death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.736
elevated	GeneRIF Biological Term Annotations	1.0	null
adhesion	GeneRIF Biological Term Annotations	1.0	null
aktdependent	GeneRIF Biological Term Annotations	1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Abortion, Tubal	DisGeNET Gene-Phenotype Associations	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.79474
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20829
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2291
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046185
ketoconazole-1285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
death	GO Biological Process Annotations 2015	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25156
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.174
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
downregulating	GeneRIF Biological Term Annotations	1.0	null
prostate	GeneRIF Biological Term Annotations	1.0	null
burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105409
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K46311453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37299
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3216
Acne	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.62021
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75315
Laryngeal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18574
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061741
BRD-K38510068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09106
BRD-K99638698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39324
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
BRD-K68547601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30855
EHMT2_KD_GSE34925_693_human_MDA-MB231 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-SNU-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.96377
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
JUN_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interleukin-10 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.439
possible	GeneRIF Biological Term Annotations	1.0	null
p3 part of the ZL core	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39853
EE-01-FB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.785618
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.782926
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33097
primaquine-1343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
degree	GeneRIF Biological Term Annotations	1.0	null
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.756
Acetylcysteine	CTD Gene-Chemical Interactions	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Microphthalmia with limb anomalies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
radiosensitization	GeneRIF Biological Term Annotations	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
phosphorylation	GO Biological Process Annotations 2015	1.0	null
PMC7902901-Table_12.xlsx-STAT1-Unnamed_7_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammatory Dermatosis	DisGeNET Gene-Disease Associations	1.0	null
HHUA	DepMap CRISPR Gene Dependency	1.0	3.2032
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44797
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.595
BRD-K08006576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15261
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430629
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.02836
Perturb_12262_KD_SIRT1/IGF2BP2_SRP334258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
il6	GeneRIF Biological Term Annotations	1.0	null
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25131
psoriatic	GeneRIF Biological Term Annotations	1.0	null
Lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.533
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Vasculitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880057
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29033
17284527-TableS4	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21156
appendix	HPA Tissue Gene Expression Profiles	1.0	0.896204
interleukin-2 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61766
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.677
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.9456
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16566
OVCAR8	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59196
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT1080	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_11_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55579
Brain Lower Grade Glioma_LGG_TCGA-DU-5854-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61996
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.7941
PMC7037253__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00676
MDA-MB-453	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82677
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.54217
PMC9233125__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.295
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7859
Microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
propranolol_mus musculus_gpl6885_gse42534	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20046
metastatic melanoma	GAD Gene-Disease Associations	1.0	null
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.773741
changing	GeneRIF Biological Term Annotations	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7269
BRD-K25805580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50078
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571619
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34229
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
activate	GeneRIF Biological Term Annotations	1.0	null
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21718
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.739
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28826127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3959
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.781
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03589
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00903
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.53408
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93415
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40276277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70548
effect	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977442
QA-34-PH05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.776014
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996424
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54769
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15781
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854425
MAZ	ENCODE Transcription Factor Targets	1.0	null
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Aggressive Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
Respiratory epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
BRD-K84939696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14942
hsa-miR-300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cytokinelike	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15029
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.44515
BRD-K66590796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20743
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86751
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.67953
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37049577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34502
tool	GeneRIF Biological Term Annotations	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873914
BRD-K30530468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87871
myofibroblasts	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.465
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91946
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AM-38	GDSC Cell Line Gene Expression Profiles	1.0	1.74737
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
BRD-K01250897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47042
Perturb_11438_KO_RB1/TP53_SRP253428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76561
manifest	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K79494396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09204
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.428359
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073197
BRD-K65184008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18988
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078926
SP1	ENCODE Transcription Factor Targets	1.0	null
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERGIC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00774125
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.167
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4647707__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Spleen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.271
Diabetes Mellitus	CTD Gene-Disease Associations	1.0	1.23169
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18711
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00213
DC-81-PH69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247413
SMZ1	DepMap CRISPR Gene Dependency	1.0	7.19222
invasion	GeneRIF Biological Term Annotations	1.0	null
Trachea-connective tissue cell	Tabula Sapiens Gene-Cell Associations	1.0	0.205666
CRCGN016_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9538
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37037
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65569
Perturb_10229_OE_miR148a_SRP362328	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8364
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884858
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233731
suppresses	GeneRIF Biological Term Annotations	1.0	null
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061476
Perturb_10200_KD_HNRNPUL1_ERP118119	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13252
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
interleukin-35 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.149
inversely	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
therapeutic	GeneRIF Biological Term Annotations	1.0	null
Perturb_13601_KD_YAP1_SRP337871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.15414
BRD-A93236127_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.8265
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
Depression_Cerebral cortex_GSE12654	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.44369
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.31965
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
SKOV-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
Cleft Palate	CTD Gene-Disease Associations	1.0	1.04051
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8882
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37872
NMRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590856
Allantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
recombinant	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87505
SOX4_01_140	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.63103
cyclobenzaprine-1332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866754
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
oxedrine-7150	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K47650707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22816
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
SMMC-7721 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.857609
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.21695
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01109
arthritis	GeneRIF Biological Term Annotations	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936387
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
tnfstimulated	GeneRIF Biological Term Annotations	1.0	null
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.363043
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60393
while	GeneRIF Biological Term Annotations	1.0	null
distinguished	GeneRIF Biological Term Annotations	1.0	null
Th2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
control	GeneRIF Biological Term Annotations	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Ripoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.11549
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29603
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
member	GeneRIF Biological Term Annotations	1.0	null
Bronchiolitis, Viral	HuGE Navigator Gene-Phenotype Associations	1.0	null
16715129-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	2.31329
PMC3805541__F3	PFOCR Pathway Figure Associations 2024	1.0	null
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50033
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
naftifine-2974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.483631
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96095
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.69124
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
D423MG	DepMap CRISPR Gene Dependency	1.0	2.96244
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860075
JUND	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
ubiquitinated	GeneRIF Biological Term Annotations	1.0	null
PB-09-OE00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.15778
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56167
PMC7395311__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.604113
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46787
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05894
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
Sebaceous gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
physiologic	GeneRIF Biological Term Annotations	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
cellular response to lipid	GO Biological Process Annotations 2015	1.0	null
Pustulosis Of Palms And Soles	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24778
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
BC-81-LO06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202229
AD-52-UZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324477
Latent Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
cellular response to interleukin-4	GO Biological Process Annotations 2015	1.0	null
D425	DepMap CRISPR Gene Dependency	1.0	2.58433
sulfadimidine-4322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO Biological Process Annotations 2015	1.0	null
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fh4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
pentoxifylline-7319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.379913
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90251
BRD-K07385991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15676
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00812
pharmacological	GeneRIF Biological Term Annotations	1.0	null
MAP2K3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00419191
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925635
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11096
Perturb_185_KD_Mgp_SRP048752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.35942
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.525166
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40894
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060429
BRD-K00610900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35916
BRD-K93846199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37908
CRCGN016_MCF10A.TP53.M_24H:P11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43063
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.882
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54441
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33156
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947397
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.828062
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
DYRK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611758
BRD-K96144282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73333
arrest	GeneRIF Biological Term Annotations	1.0	null
CMT-93 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4139
SW1573	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4853
genebased	GeneRIF Biological Term Annotations	1.0	null
IPC-298	GDSC Cell Line Gene Expression Profiles	1.0	2.40759
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5862
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44422
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.818
PMC6556902__F3	PFOCR Pathway Figure Associations 2024	1.0	null
apaf1	GeneRIF Biological Term Annotations	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2264
lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589635
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.995028
TCF12_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881597
hsa-miR-612	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SARS-BatSRBD_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90044
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85888199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20749
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65937
inhibitory	GeneRIF Biological Term Annotations	1.0	null
spiramycin-4319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K81372870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32488
16740760-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE215086_4_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tanespimycin-1206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234878
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
GSE129725_1_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12282
PMC5742522-peerj-05-4214-s005.xlsx-Sheet1-Strabismic_medial_rectus_MR_vs_donor_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
many	GeneRIF Biological Term Annotations	1.0	null
RET_mutant_23_GDS3319	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57024
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48373
BRD-K52001024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17268
Autoimmune uveitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.280406
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21946
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
PMC6386537__F3	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09515
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-2.13474
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
identification	GeneRIF Biological Term Annotations	1.0	null
PMC6386537__F3	PFOCR Pathway Figure Associations 2024	1.0	null
interleukin-20 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.207
Meningococcal infection_Umbilical vein_GSE4646	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51635
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
renal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120952
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284253
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52989
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
maternalfetal	GeneRIF Biological Term Annotations	1.0	null
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.40884
BRD-K76763044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10621
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
hsa-miR-205-5p	MiRTarBase microRNA Targets	1.0	null
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Perturb_15539_Mut_Ezh2_SRP220248	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71883
senescence-associated heterochromatin focus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.56936
subcellular	GeneRIF Biological Term Annotations	1.0	null
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22134
3-hydroxy-DL-kynurenine-5641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IE-19-LI00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.253642
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67227
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.35402
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848168
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.600644
Perturb_336_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17614
homochlorcyclizine-7295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918032
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36405
protein binding	GO Molecular Function Annotations 2015	1.0	null
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ROCK2_knockdown_157_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.11069
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28297
organelle	GO Cellular Component Annotations 2015	1.0	null
negative regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
BRD-K88538240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03945
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Plasmacytoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
CRCGN015_HEPG2_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19088
posttranscriptional	GeneRIF Biological Term Annotations	1.0	null
extracellular space	GO Cellular Component Annotations 2015	1.0	null
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66113
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20077
17313671-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
pivmecillinam-2973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BC-76-HY47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355829
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847282
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6278
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50198
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065263
Autoimmune disease of eyes, ear, nose and throat	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
Synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Hidradenitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911576
nifuroxazide-4253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MOLM14	DepMap CRISPR Gene Dependency	1.0	4.83687
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_24_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2091
PMC7598934__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03931
BB-11-JI42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12718
Perturb_8982_OE_MEOX2_SRP362177	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.587841
Meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
BRD-K16149312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05483
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
Lymphatic Metastasis	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29165
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
blasts	GeneRIF Biological Term Annotations	1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Urinary Tract Infection	DisGeNET Gene-Disease Associations	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30566330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08127
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO Biological Process Annotations 2015	1.0	null
GSE228619_0_v_1_cdh11_human	RummaGEO Gene Perturbation Signatures	1.0	null
vector	GeneRIF Biological Term Annotations	1.0	null
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.299569
interleukin-9 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
Perturb_14573_KO_EP300_SRP336466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.94898
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68356
tRNA methyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.203
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
18081427-TableS7	GeneSigDB Published Gene Signatures	1.0	null
cellmediated	GeneRIF Biological Term Annotations	1.0	null
Secondary Malignant Neoplasm Of Bone	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17599
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HTR-8/SVneo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
1,4-chrysenequinone-1773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypertriglyceridemia	CTD Gene-Disease Associations	1.0	1.41775
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
NCIH889	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46159
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.941
Perturb_12503_KD_ESR1_ERP130561	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.87909
TCF4	ChEA Transcription Factor Targets	1.0	null
profile	GeneRIF Biological Term Annotations	1.0	null
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.61883
GSE215086_4_v_6_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125403_3_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39067
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7347
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.841491
focal	GeneRIF Biological Term Annotations	1.0	null
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65194
cephaeline-4651	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.470763
promote	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3704
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.34459
GC-57-HV87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.238531
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28106
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34085
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16584
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
tissue	GeneRIF Biological Term Annotations	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.3039
GNB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496214
BRD-K91085913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06442
Ovary adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81959
Ventral aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08261
Conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
Langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.655713
profound	GeneRIF Biological Term Annotations	1.0	null
PMC7076804__F5	PFOCR Pathway Figure Associations 2023	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44202
melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5709591__F5	PFOCR Pathway Figure Associations 2023	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15353
BRD-K31466024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7301
Vitiligo-Associated Multiple Autoimmune Disease	DisGeNET Gene-Disease Associations	1.0	null
DA-81-VY50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.740913
HMV-II cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
anisomycin-6764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849035
CUX1	ChEA Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75943
Perturb_16785_KD_AMIGO2_SRP369776	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5978
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25013674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3373
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859632
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nasopharynx carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44181
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31676
MZ2-MEL	GDSC Cell Line Gene Expression Profiles	1.0	2.34519
signal	GeneRIF Biological Term Annotations	1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1641
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sodium Dodecyl Sulfate	CTD Gene-Chemical Interactions	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10769
BRD-K35799753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09377
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	CTD Gene-Chemical Interactions	1.0	null
BRD-K63730594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97009
16740760-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20125
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88493
Perturb_15557_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.75021
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chrysin-3106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18316
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1296
BRD-K44624253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40874
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
kinase	GeneRIF Biological Term Annotations	1.0	null
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308894
BRD-K09995054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24482
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81921
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Malignant Glioma	DisGeNET Gene-Disease Associations	1.0	null
COLO704	CCLE Cell Line Gene CNV Profiles	1.0	1.36255
USF2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0324
apoptotic	GeneRIF Biological Term Annotations	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.37247
Childhood Burkitt Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57298
EIF2AK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00521843
asthma; bronchiolitis, viral; respiratory syncytial virus infections	GAD Gene-Disease Associations	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.013
pramocaine-2198	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
erbb1	GeneRIF Biological Term Annotations	1.0	null
FA-16-HR75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234316
meptazinol-2906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73035
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.14989
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071568
PMC12875250-peerj-14-20707-s004.docx-0-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.589001
hsa-miR-429	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3609811__F2	PFOCR Pathway Figure Associations 2024	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897483
cancerspecific	GeneRIF Biological Term Annotations	1.0	null
Adult Rhabdomyosarcoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K00765599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7763
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
interleukin-28 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
SF268	BioGPS Cell Line Gene Expression Profiles	1.0	1.09096
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
A375	CCLE Cell Line Gene Expression Profiles	1.0	1.64321
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910228
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.84
BRD-K23857235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58766
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.579365
nci-h460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
ticarcillin-6146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10326_KO_Shp1_SRP370028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.5751
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7156
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695354
PMC7902901-Table_12.xlsx-SPIB-Unnamed_7_SPIB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
RXRA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30982
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	0.883832
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	2.18868
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29153
regulation of cell motility	GO Biological Process Annotations 2015	1.0	null
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DV90	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83512
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1006
16434974-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K42185771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19311
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
other organism part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123533
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.606293
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7517
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.55945
BRD-K65005311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3198
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.52773
icam1	GeneRIF Biological Term Annotations	1.0	null
BRD-K39247583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28046
Pyoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8927
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7176
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44608
Necrosis	CTD Gene-Disease Associations	1.0	2.20647
BRD-K94444134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12376
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.04501
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071439
BRD-K56950366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47034
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59963
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859342
TCF3	ENCODE Transcription Factor Targets	1.0	null
enhancing	GeneRIF Biological Term Annotations	1.0	null
Pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
periventricular stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27362
Nephritis	DisGeNET Gene-Disease Associations	1.0	null
alternative	GeneRIF Biological Term Annotations	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
Perturb_13600_KD_DDIT3_SRP337871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61352
Prostate epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38044
BRD-K71737889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38657
Perturb_2875_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
JAK2_druginhibition_167_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.33785
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853504
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
MS-275-7074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21278
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10675
positive regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
pyrvinium-2957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.845294
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
direct	GeneRIF Biological Term Annotations	1.0	null
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2814
Gbm cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055511
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23429
MiaPaCa-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
specific	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE150688_2_v_0_ursolic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
suppressed	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57383
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.612471
specificity	GeneRIF Biological Term Annotations	1.0	null
JF-55-EN33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.61856
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21128
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839339
PANC0504	DepMap CRISPR Gene Dependency	1.0	5.42633
Perturb_15163_KD_PGR_SRP097736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.99897
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76902
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.17784
BC-09-XQ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378785
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Malignant Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
cardiovascular	GeneRIF Biological Term Annotations	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03378
PMC7470101__F1	PFOCR Pathway Figure Associations 2023	1.0	null
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.895734
response to lipid	GO Biological Process Annotations 2015	1.0	null
Cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8793
gabexate-2937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01208
chlorpromazine-5074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28231
hsa-miR-3135	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K71339292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23906
likelihood	GeneRIF Biological Term Annotations	1.0	null
BRD-K54099984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38201
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76865
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952593
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.831
BRD-K97938633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11729
tyrosine	GeneRIF Biological Term Annotations	1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
BRD-A52650764_Ingenol 3, 20-dibenzoate_OV7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
potentially	GeneRIF Biological Term Annotations	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48501
Lung Diseases	CTD Gene-Disease Associations	1.0	1.29595
BRD-K65868510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01326
autophagy	GeneRIF Biological Term Annotations	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07683
endoplasmic reticulum	GO Cellular Component Annotations 2015	1.0	null
GSE235828_3_v_2_igf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60694
19139136-TableS2	GeneSigDB Published Gene Signatures	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.557897
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.987898
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.779
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Hecv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16264250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50488
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.681064
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.178
ceramide	GeneRIF Biological Term Annotations	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02875
autocrine	GeneRIF Biological Term Annotations	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
determine	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06546
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.36116
Perturb_9819_KD_HEB_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61029
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K75626008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34155
Perturb_1121_KD_E2APBX1_SRP115954	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.7647
Diffuse Large B-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
destabilization	GeneRIF Biological Term Annotations	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55266
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
DC-23-UM36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.679645
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	2.24993
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
496100371_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.46163
tnf	GeneRIF Biological Term Annotations	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.552
Perturb_17525_KO_Foxp3_SRP366054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.1733
TE-26-XS06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246296
3'-fluorobenzylspiperone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43238
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6002
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
bendroflumethiazide-4315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
facilitates	GeneRIF Biological Term Annotations	1.0	null
Perturb_3838_KO_ITPR3_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.35068
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38599
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.422515
NCI-H460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.4342
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045402
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
KYSE150	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54711
BRD-K44946060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58842
PMC12436147-41380_2025_3032_MOESM1_ESM.xlsx-ST3-Supplementary_Table3_Blood_eQTLs_that_were_selected_as_genetic_instruments_for_MR_analyses_eQTLGEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
mediating	GeneRIF Biological Term Annotations	1.0	null
skin cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08741
hsa-miR-4758-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25114
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883025
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20215591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20234
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pizotifen-3134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterus-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.137844
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	5.69611
cytokine	GeneRIF Biological Term Annotations	1.0	null
BRD-A64985224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45502
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
radiationinduced	GeneRIF Biological Term Annotations	1.0	null
noscapine-1753	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
signals	GeneRIF Biological Term Annotations	1.0	null
Senescence and Autophagy(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9322
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063371
Chronic spontaneous urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.504
microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70845
Splenial gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
tuberculosis	GeneRIF Biological Term Annotations	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.238
GSE243199_1_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.172
response to stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858116
activities	GeneRIF Biological Term Annotations	1.0	null
PMC5445595__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Tumor necrosis factor receptor superfamily complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Perturb_14155_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.645
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09752
CRCGN015_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02883
HSC3	CCLE Cell Line Gene Expression Profiles	1.0	2.04767
immortalized	GeneRIF Biological Term Annotations	1.0	null
upregulated	GeneRIF Biological Term Annotations	1.0	null
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07646
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5027
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
Germinal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
hydralazine-4282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC3565070__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
geldanamycin-6187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
seldom	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77575
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.508635
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.979955
methyltransferase	GeneRIF Biological Term Annotations	1.0	null
nifedipine-1814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Bongkrekic Acid	CTD Gene-Chemical Interactions	1.0	null
BRD-K94777797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41263
Perturb_15571_OE_circCSPP1_SRP286288	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MAP2K4_knockdown_62_GSE19091	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.959431
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SW-620 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982762
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
DNMT3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00333656
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30281
GTEX-S4Q7-0526-SM-4AD5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02822
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12703266-gutjnl-75-1-s002.pdf-29-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95538
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hep-G2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.629
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897013
GSE253799_0_v_1_matn3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6088
PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96921
Perturb_14147_KD_RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10547
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
node	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5318-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938504
wortmannin-2703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
procainamide-1263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86554
Esophageal Neoplasms	CTD Gene-Disease Associations	1.0	1.09226
GINS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00404882
emetine-4243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572018
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67185
Pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.753
Perturb_351_OE_CD274_SRP287831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.6574
K562	DepMap CRISPR Gene Dependency	1.0	6.26968
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03839
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06432
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4104
E2F4	ENCODE Transcription Factor Targets	1.0	null
EF-85-DA07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265232
toxicity	GeneRIF Biological Term Annotations	1.0	null
Skin-stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	5.04042
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48675
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.238
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01577
18849563-SuppTable5b	GeneSigDB Published Gene Signatures	1.0	null
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95624
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6013441__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Astrocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
host intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.609086
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873204
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580017
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.661
Myeloid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
negative regulation of locomotion	GO Biological Process Annotations 2015	1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03481
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.599104
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870425
BRD-K76541957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68055
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63496
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895306
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
squamous	GeneRIF Biological Term Annotations	1.0	null
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
RXRA	ENCODE Transcription Factor Targets	1.0	null
MELJUSO	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
GSE221386_3_v_0_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trifluoperazine-4448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55544
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	2.79307
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.24338
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HEMn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
U 0126	CTD Gene-Chemical Interactions	1.0	null
melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764054
adenovirusmediated	GeneRIF Biological Term Annotations	1.0	null
progenitor	GeneRIF Biological Term Annotations	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20595
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16165
BRD-K31852848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24066
thioguanosine-1264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
following	GeneRIF Biological Term Annotations	1.0	null
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.70511
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Type I pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.699626
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.664
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
equilin-4659	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	1.11673
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.326
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874667
methylergometrine-1607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
ils	GeneRIF Biological Term Annotations	1.0	null
inflamed	GeneRIF Biological Term Annotations	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41117
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Abortion, Spontaneous	CTD Gene-Disease Associations	1.0	2.88009
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24426
transformed	GeneRIF Biological Term Annotations	1.0	null
CACNG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614356
production	GeneRIF Biological Term Annotations	1.0	null
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
JAK2_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
ovarian epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485935
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Kidney cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
ethosuximide-7308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.618012
unparalleled	GeneRIF Biological Term Annotations	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.20241
Oral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.205
myeloid leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072511
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
salbutamol-3677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
KIJK	CCLE Cell Line Gene CNV Profiles	1.0	1.34967
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1563
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.875
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528398
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.952
minoxidil-1914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Downregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Death	CTD Gene-Disease Associations	1.0	1.20097
BRD-K69780027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10846
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08305
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
Mammary Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2379
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8594
PKD2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467691
PMC10808687-Table_1.xlsx-Supplementary_Table_4-Supplementary_Table_4_Discovery_of_positive_MR_analysis_results_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.177
Interferon regulatory factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
HA-32-YH61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.688173
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07206
Metastatic Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64133
Endometrial stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
intracellular	GeneRIF Biological Term Annotations	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
rimexolone-2955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mouse	GeneRIF Biological Term Annotations	1.0	null
igr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13473
Poisoning	CTD Gene-Disease Associations	1.0	1.47787
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367609
GTEX-NFK9-0326-SM-3MJGV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Rheumatoid arthritis disease specific synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
ATM_KD_GSE54268_662_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
KC-26-JQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234222
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
HA-17-MS45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.351281
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51W-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PD-60-FM93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348281
procarbazine-3533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
SK-MEL-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98497
vectors	GeneRIF Biological Term Annotations	1.0	null
palmoplantar	GeneRIF Biological Term Annotations	1.0	null
Metastatic Melanoma	DisGeNET Gene-Disease Associations	1.0	null
erlotinib	GeneRIF Biological Term Annotations	1.0	null
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.73632
IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.617
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29164
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.721713
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27068
because	GeneRIF Biological Term Annotations	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17771
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62809
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110804
Tetrad of microspores	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4121
muscle	GeneRIF Biological Term Annotations	1.0	null
CP-690334-01-3823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.054
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.754
PMC3827940-2045-3329-3-12-S1.docx-1-Supplementary_Table_2_Minor_allele_frequencies_MAF_and_p-values_for_comparison_of_genotype_frequencies_Z9001_genotyped_whites_n_273_versus_non-whites_n_58_1_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	GO Biological Process Annotations 2015	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-RAF_UP_V1_DN-Gene_name_ZHX2	Rummagene Transcription Factor Associations 2026	1.0	null
targeted	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Perturb_12159_OE_TCF7_SRP144189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81385
melanomas	GeneRIF Biological Term Annotations	1.0	null
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.347144
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Myofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824927
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZEB2_01_56	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.78464
Human - Pancreas - L1 - quiescent stellate	HuBMAP Azimuth Cell Type Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21729626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23018
perphenazine-1956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	2.16787
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24119
Perturb_5546_Mut_MB21D2_SRP277311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.20231
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.90325
mediates	GeneRIF Biological Term Annotations	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09821
molecular	GeneRIF Biological Term Annotations	1.0	null
reserpine-3003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93726930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51172
cytokine cytokine receptor interaction	KEGG Pathways	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BC-00-YH62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252755
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825377
CHD1	ENCODE Transcription Factor Targets	1.0	null
interleukin-4 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
mda7il24	GeneRIF Biological Term Annotations	1.0	null
BRD-K39664334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1259
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88673
Perturb_1370_KD_IGF2BP1_SRP252209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.2742
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2295
laudanosine-7270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spondyloarthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
Renal cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17107
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Perturb_970_OE_SRSF1_SRP174924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6168
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23428
phenotypes	GeneRIF Biological Term Annotations	1.0	null
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95535
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the solitary tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01382
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39511
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05175
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728152
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931682
FD-25-KX07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.51631
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JUND_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spondylarthritis	DisGeNET Gene-Disease Associations	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.42562
namalwa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.436055
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11595_KD_CGAS_SRP107235	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.11306
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
S0-EE-Y4UM_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217682
MITF_01_207	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.71265
hsa-miR-3121-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Fibroblast	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98453
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0345
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.77086
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
Mechanical Allodynia	DisGeNET Gene-Phenotype Associations	1.0	null
T-47D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46833
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377491
epirizole-1845	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inflammatory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.836
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881987
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870335
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26874
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896436
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01338
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901139
CF-48-QD87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.475757
PMC8108288-gutjnl-2020-321731supp005.xlsx-LPS_stimulation-gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.54387
METTL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84721
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
Pain	CTD Gene-Disease Associations	1.0	1.40373
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571219
Childhood Acute Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.312
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
PPARGC1A_KO_GDS2391_299_mouse_brain striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.83968
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1456
Foreskin fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49467
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352598
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20018718-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Pancreatitis	DisGeNET Gene-Disease Associations	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	0.973757
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	1.49679
negative regulation of cell death	GO Biological Process Annotations 2015	1.0	null
Conventional (Clear Cell) Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49175
Prostate adenocarcinoma_PRAD_TCGA-VP-A87C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JD-87-KA71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353667
TRIM24_knockout_300_GSE19675	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.58927
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98383
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91776
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
cg86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
PMC8010670-Table_5.XLSX-Monocyte_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48622
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858311
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6305
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
bystander	GeneRIF Biological Term Annotations	1.0	null
puromycin-2448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
N-acetylmuramic acid-4582	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372576
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03786
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
apoptosisinducing	GeneRIF Biological Term Annotations	1.0	null
doxorubicin_homo sapiens_gpl96_gse12972	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Memory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
lasalocid-3021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8388390__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
serine phosphorylation of stat protein	GO Biological Process Annotations 2015	1.0	null
BRD-K29935988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64237
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527442
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
line	GeneRIF Biological Term Annotations	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
Physical urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
Liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.826
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0119
MITF	ChEA Transcription Factor Targets	1.0	null
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0756
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10561055-mmc3.xlsx-LPS_T0-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76210487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06661
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00063
M1 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.955
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-369-TTF1_TTF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51363
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.68479
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04482
CF-42-OS28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347464
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05721
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886901
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Macaque_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HEp-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
ethoxyquin-4321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865725
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
respond	GeneRIF Biological Term Annotations	1.0	null
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4822853__F3	PFOCR Pathway Figure Associations 2024	1.0	null
hepatitis c	GAD Gene-Disease Associations	1.0	null
JUND_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7958
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27381
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89064
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-344-GBX1_GBX1	Rummagene Transcription Factor Associations 2026	1.0	null
mestizo	GeneRIF Biological Term Annotations	1.0	null
wound healing	GO Biological Process Annotations 2015	1.0	null
BRD-A52650764_Ingenol 3, 20-dibenzoate_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065618
Cytokine Signaling in Immune system	Reactome Pathways 2024	1.0	null
hydroquinine-1775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4266326__F2a	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_638_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.3669
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423054
isoxicam-1862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04524
PMC5915057__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62373
Perturb_14150_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200381
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966112
Inflammation	CTD Gene-Disease Associations	1.0	2.2892
cell lysate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3976
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408972
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
addition	GeneRIF Biological Term Annotations	1.0	null
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07894
PMC4595011-pgen.1005555.s002.xlsx-MITF_UP_in_30kb-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTSW	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488444
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57229
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
methapyrilene-4990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.30208
Perturb_15561_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.60282
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897548
BRD-K91576495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10236
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
A-549 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615