association	dataset	threshold value	standardized value
hsa-miR-584	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.67933
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62725
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73853
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6078_KD_TARDBP_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.8614
hsa-miR-4537	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Hemorrhage	CTD Gene-Disease Associations	1.0	1.18521
Regio orbitalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
A101D	CCLE Cell Line Gene Expression Profiles	1.0	1.63591
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53657
hsa-miR-410	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49971
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15568
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07228
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.69961
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37602
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60405
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
paclitaxel_homo sapiens_gpl570_gse19136	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09757
N-nitrosomorpholine	CTD Gene-Chemical Interactions	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.89758
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57814
Perturb_10909_KD_Eif3m_SRP157047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.141
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0573
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43276
GATA1	ENCODE Transcription Factor Targets	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	2.00982
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5371
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72918
H4	CCLE Cell Line Gene CNV Profiles	1.0	2.21256
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882186
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14729
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042498
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80693
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48849
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041611
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.78351
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7171
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-01-RI07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.402907
Perturb_11335_KO_Bmal1_SRP060296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64666
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849214
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25299
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882186
GSE121009,GSE121014_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tobacco Smoke Pollution	CTD Gene-Chemical Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11759_OE_Ddah1_SRP027595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.63626
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.10631
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01443
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18994
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9586
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
HLF	DepMap CRISPR Gene Dependency	1.0	2.00896
Type II protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127273
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.29861
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26997
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1701
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
ERCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80505
improved glucose tolerance	IMPC Knockout Mouse Phenotypes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33728
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
hsa-miR-4662a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20544
Perturb_16364_KO_Cryab/Hspb2_SRP055864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.55524
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04249
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3218
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.82894
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.13007
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	2.76653
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55992
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05386
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58441
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	1.82128
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8556
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03189
TMEM82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16115
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.013
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966252
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07607
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.404
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19408
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43294
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61127
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.299569
PMC11481653-mmc33.pdf-138-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15155
spina bifida	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.781479
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34582
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42599
estradiol_mus musculus_gpl75_gse280	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ntera2	HPA Cell Line Gene Expression Profiles	1.0	0.842001
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.002
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49925
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.20913
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.34914
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25534
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857864
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055659
DLX1_02_55	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.43741
18394172-S4GeneList	GeneSigDB Published Gene Signatures	1.0	null
Perturb_10798_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.902
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04749
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16473
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30837
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02955
Perturb_9221_KO_Scgn_SRP396836	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.07614
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27548
Integral component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_11187_KO_Trp53/Gdown1_SRP244620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.89889
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928963
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7147
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thymus-medullary thymic epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.54489
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.43197
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16678
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058478
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4371
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tryptamine	HMDB Metabolites of Enzymes	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05324
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28734
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13589
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7759
Heart Septal Defects, Ventricular	CTD Gene-Disease Associations	1.0	1.17926
Perturb_18146_KO_Nampt_SRP245819	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.91952
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tryptophan metabolism(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00957
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146134
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6274
Learning Disorders	CTD Gene-Disease Associations	1.0	1.54208
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94312
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.08266
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5313
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58053
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Perturb_9700_KO_TREX1_SRP355094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09839
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13304
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04422
culture fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62385
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.132
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97418
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphatic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51292
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.07112
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38648
PMC12714181-pone.0337892.s004.xlsx-Supplementary_Table2-S4_Table_Differential_expressed_genes_between_si-CEBPB_and_si-NC_HCT116_cells_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
baclofen_mus musculus_gpl1261_gse17266	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
15845616-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06693
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10747
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78716
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19694
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.33995
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32833
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24882
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79426
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18013
KAT2A	ENCODE Transcription Factor Targets	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4947
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09201
PMC4859987__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83487
Neoplasms	CTD Gene-Disease Associations	1.0	1.8215
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62155
Perturb_3006_KD_FAP_SRP285807	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.81168
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-11A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10816_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.15706
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.593
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31371
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897092
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.80466
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03607
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04249
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60478
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37779
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18972
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19597
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45897
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3518
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49669
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Gene_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043808
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882511
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933159
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18123
Perturb_11746_KO_Mek2_SRP321493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.44339
PMC4552674-pone.0136569.s005.xlsx-Blad1-DOWNSTREAM_MOLECULES_OF_NFE2L2_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-449	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_6094_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_10596_KO_Nr1h3/Nr1h2_SRP351084	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.12251
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17898
PMC6433273-pone.0214296.s009.xlsx-Table_C-S3_Table_Differentially_expressed_mRNAs_in_human_primary_monocytes_after_6_hours_of_LPS_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22152
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73851
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	2.18155
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12777
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081419
H2BK20ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-379	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7762
Methylation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
amine n-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72067
periventricular stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09741
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21608
ce92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04303
NMCG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43106
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2475
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49976
abnormal lymph node morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855734
hsa-miR-1268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289199
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792709
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46878
Hirschsprung's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12560_KD_Setd2_SRP323765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
response to stimulus	GO Biological Process Annotations 2015	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N-Methyltryptamine	MW Enzyme Metabolite Associations	1.0	null
Perturb_6087_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.5757
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05353
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lung_3f	HPA Tissue Sample Gene Expression Profiles	1.0	1.411
Hepatomegaly	CTD Gene-Disease Associations	1.0	2.2196
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.10769
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-606-ENSG00000050344_NFE2L3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
laminin-4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8545
Brain Lower Grade Glioma_LGG_TCGA-DB-5276-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
Tryptamine	MW Enzyme Metabolite Associations	1.0	null
SNU626	CCLE Cell Line Gene CNV Profiles	1.0	1.33782
Perturb_7111_KO_Atf4_SRP344236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.94774
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
TFDP1_02_71	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27426
CLOCK-20551151-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F8-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13871
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8766
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871942
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0622
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98518
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862355
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09232
TP53_01_68	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.58111
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61569
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19123
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72158
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91914
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041728
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.10104
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16577
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.53872
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
Succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43195
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12768
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13349
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926706
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01758
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.591
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4883
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SKMEL5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73773
HS834T	CCLE Cell Line Gene Expression Profiles	1.0	1.52131
OC315	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24484
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642858
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.04
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00062
SNU81	DepMap CRISPR Gene Dependency	1.0	3.09421
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47077
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36491
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.829
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
OV7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.1893
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.74882
GSE183890_7_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.852698
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10047
AGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14866
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.924254
Fetal Death	CTD Gene-Disease Associations	1.0	1.87875
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1405
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31877
Perturb_11603_KD_AKR1C1_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55727
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6777-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96662
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065
hsa-miR-3529	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4754
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19129
Nephrolithiasis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16596
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057905
Perturb_11129_KO_Yap1_SRP281955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75398
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12035
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22462
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3225
McLeod syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16653
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Perturb_17680_KO_Foxo1_SRP063560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
C19orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22936
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7959
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70826
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17561
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11885_KO_Stat3_SRP307561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.72312
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6976
Perturb_16099_KO_Eed_SRP125082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.48261
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10325_KO_Gsdmd_SRP318237	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.93182
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02101
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89333
TP63_01_201	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.00368
Perturb_6025_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.8813
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070194
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.829074
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26302
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46382
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOC5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09279
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39029
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	2.35464
amine N-methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE159084_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69268
NFATC1_02_22	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.62449
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.23291
Acute Myeloid Leukemia_LAML_TCGA-AB-2881-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069933
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910833
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS53	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60423
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Electron transfer flavoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12615
ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927952
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94765
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069113
Seizures	CTD Gene-Disease Associations	1.0	1.08833
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13463
Poisoning	CTD Gene-Disease Associations	1.0	1.41856
RS411	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01075
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11122_KD_Eif3m_SRP162708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.141
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98677
DROSHA-22980978-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11159_KO_Foxo1_SRP094428	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.6669
PMC8705244__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1781
NCIH596	CCLE Cell Line Gene CNV Profiles	1.0	1.86966
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19203
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91593
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7924
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
propiconazole	CTD Gene-Chemical Interactions	1.0	null
Lymphoid dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2603
hsa-miR-3927	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46765
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83347
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.35855
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09041
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044989
enlarged lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
Parabrachial nucleus, medial division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12187
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42224
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01486
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09359
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03284
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883243
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2256
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0756
c2c12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4269
everolimus_mus musculus_gpl6885_gse37129	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937854
GSE127970_2_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.07896
CBX3	ENCODE Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859019
Fever	CTD Gene-Disease Associations	1.0	1.17695
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11828
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.677238
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43611
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33698
Mental Disorders	CTD Gene-Disease Associations	1.0	1.13929
Perturb_11640_KD_ITCH_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.88915
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.489474
Perturb_10846_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45927
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01795
Perturb_10797_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.42195
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38776
ER membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42373
NFYA_02_76	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.45943
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1313
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.971
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1973
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54818
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6439317-Table_4.XLSX-NR2F6-Supplementary_Table_4_Genes_with_significant_correlation_with_NR2F6_NR2F6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.53127
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8651
HCC15	DepMap CRISPR Gene Dependency	1.0	5.1618
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40812
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3273
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041269
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31529
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.63009
NCI-H226	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13467_Mut_Ar_SRP045727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
15845616-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80845
Weight Gain	CTD Gene-Disease Associations	1.0	1.66188
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8481
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43294
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051013
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10734
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838487
DBTRG05MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.87444
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-4700-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.878442
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-22025678-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93075
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28531
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896191
Parabrachial nucleus, medial division, medial medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38204
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0654
CBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04646
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.32794
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Substance Withdrawal Syndrome	CTD Gene-Disease Associations	1.0	1.36304
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07728
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18044
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enlarged lymph nodes	IMPC Knockout Mouse Phenotypes	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91339
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.24623
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21978
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887097
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06155
BRD4_knockdown_223_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.22676
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06624
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14029
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10732
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3681
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10089
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
isthmic part of mesencephalic trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1758
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874846
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23006
DPF2_02_14	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.11548
PMC7347220__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_10834_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.49745
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66197
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.088811
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-198	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Adenoma	CTD Gene-Disease Associations	1.0	1.02114
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01541
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00861
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66655
RNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64849
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19993
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.621379
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8311
STAT6_02_57	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.05889
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1149
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.20145
DM3	CCLE Cell Line Gene Expression Profiles	1.0	2.04118
Metapathway biotransformation Phase I and II	WikiPathways Pathways 2024	1.0	null
Metapathway biotransformation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11291
SNW1_02_49	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24793
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06963
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	1.20424
contractile fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243158
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00439
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24678
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Perturb_10946_KO_Nr1d1_ERP117724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.4141
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21202
USF2_02_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.81592
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24567
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25811
Dyslipidemias	CTD Gene-Disease Associations	1.0	1.26638
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00135
Glucose homeostasis traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.404
appendicitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.859771
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ID-00-IC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33384
PMC10070455-41598_2023_32568_MOESM3_ESM.xlsx-Genes_AA-genes_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
COLO818	CCLE Cell Line Gene Expression Profiles	1.0	1.63133
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS616T	CCLE Cell Line Gene Expression Profiles	1.0	1.6504
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22378
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10219
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.947475
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05116
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE1	CCLE Cell Line Gene CNV Profiles	1.0	1.75864
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935109
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.72014
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48662
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847137
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922853
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10506
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13943
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03535
Myosin XVI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.364
HDMYZ	DepMap CRISPR Gene Dependency	1.0	14.5013
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21504
Perturb_16100_KO_Map3k12_SRP157873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55212
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29649
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.947169
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13463
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10709_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3346
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TE159T	CCLE Cell Line Gene Expression Profiles	1.0	1.39892
methylation	GO Biological Process Annotations 2015	1.0	null
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12313
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hallucinogen abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
S-Adenosylhomocysteine	MW Enzyme Metabolite Associations	1.0	null
sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301425
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874692
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840217
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08123
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05314
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7889
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92089
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4468904__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71075
PMC8482636__F7	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1923
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49465
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.25059
PMC6469946-aav1472_Data_file_S3.xlsx-PPARG_targets_UP_RNA-Seq_Young-Supplemental_Table_3_PPARG_targets_up_regulated_in_dKO_vs_CONTROL_RNA-Seq_Young_FDR_0_1_n_376_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-HSLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_10893_KO_Jnk1_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.82311
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62499
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	2.59897
Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829751
Hyperplasia	CTD Gene-Disease Associations	1.0	2.16256
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17851
cytosol	GO Cellular Component Annotations 2015	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050833
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37942
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02226
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	1.20703
Hypophosphatemic nephrolithiasis/osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55085
Liver-endothelial cell of hepatic sinusoid	Tabula Sapiens Gene-Cell Associations	1.0	0.359641
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17824
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33096
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04249
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28617
IRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04794
ERRFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10854
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827767
496100531_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76848
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990018
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987848
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.94561
Perturb_11712_KO_Kpna3_ERP009054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887509
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1525
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.249608
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21215
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3439
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24784
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7312
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97154
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38725
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985901
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Vasculature-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.062675
HS940T	CCLE Cell Line Gene Expression Profiles	1.0	1.47589
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27255
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162801
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87536
EPOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03489
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24826
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73912
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29982
tryptophan metabolism	KEGG Pathways	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-468-BATF_BATF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4676-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830346
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
CDAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39501
Methyltransferase, NNMT/PNMT/TEMT	InterPro Predicted Protein Domain Annotations	1.0	null
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.965694
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01135
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37693
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47312
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899183
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74316
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043143
hsa-miR-550a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15240_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.80105
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42295
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04462
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_15133_OE_Klf10_SRP360603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.5376
GTEX-RTLS-0726-SM-46MV4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00871
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28448
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3588
Nicotine_degradation	PANTHER Pathways	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50359
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228497
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868929
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873549
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915856
Follicular dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83154
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55357
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878409
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29677
15361855-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Methylation pathways	WikiPathways Pathways 2024	1.0	null
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210580_3_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.847
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Schwalie et al.Nature.G3_Adipose tissue_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14296
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47116
hsa-miR-3673	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.752
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11858
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945813
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8566
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.462792
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30125
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946392
heart_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03742
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.40971
metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94721
Perturb_11071_KO_Slc10a1_SRP174097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.79379
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80767
Perturb_10837_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.80306
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59744
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medullary reticular cell (MedRCs)_Undefined_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18012
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22996
amine metabolic process	GO Biological Process Annotations 2023	1.0	null
subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273346
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15649
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127501
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091014
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53699
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.32273
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12619
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86121
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7912
TUBA1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5362
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45666
Lung-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0924703
Dimethyl selenide	HMDB Metabolites of Enzymes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TO175T	CCLE Cell Line Gene Expression Profiles	1.0	1.43157
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21606
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905203
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
SKMES1	CCLE Cell Line Gene CNV Profiles	1.0	1.43455
nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08957
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77679
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
786O	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00699
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39396
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18408
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33769
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33905
Perturb_10838_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96129
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.443
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1093
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3437
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95023
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37823
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.3501
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862584
GSE100316_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09912
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.61006
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872066
GSE166317_3_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60401
Serotonin	HMDB Metabolites of Enzymes	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	4.6613
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999972
PMC6756575__F3	PFOCR Pathway Figure Associations 2023	1.0	null
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0926-SM-3P5YT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00884
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GSE237040_0_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44671
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827407
PACADD161	DepMap CRISPR Gene Dependency	1.0	7.13104
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_18499_KO_TWIST1_SRP121466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871422
Trimethyl sulfonium	HMDB Metabolites of Enzymes	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18041
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50377
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1187	DepMap CRISPR Gene Dependency	1.0	6.2652
Spleen	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS895T	CCLE Cell Line Gene Expression Profiles	1.0	1.3544
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20421987-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_10712_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.4164
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.36164
Hepatitis	CTD Gene-Disease Associations	1.0	1.21076
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PANC0813	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.16462
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08109
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04635
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4167-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866653
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73147
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44339
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43609
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85022
SKMEL31	CCLE Cell Line Gene Expression Profiles	1.0	1.70024
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	1.7628
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897569
Respiratory system_CT1_alveolar type 1 fibroblast cell	HuBMAP ASCT+B Annotations	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BICR31	DepMap CRISPR Gene Dependency	1.0	2.57845
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37691
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935802
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077484
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854847
Perturb_8409_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.41554
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2185
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.257
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02845
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Diseases	CTD Gene-Disease Associations	1.0	1.08055
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053765
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36634
Perturb_9754_KO_Cfb_SRP333300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.02343
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989852
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.48416
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23257
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079783
COV644	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03908
SNU466	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
KDM5A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41922
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31548
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.15608
Tryptophan metabolism	WikiPathways Pathways 2024	1.0	null
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09527
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890459
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878409
AKT1_activemutant_10_GDS2304	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.27332
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78989
Perturb_16729_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23927
biological_process	GO Biological Process Annotations 2015	1.0	null
Perturb_3838_KO_ITPR3_SRP361791	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.59484
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840615
Perturb_10740_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6998
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4651
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66701
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-GeneExpression_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832937
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.524
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04749
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19145
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42815
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21835
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Methylation of MeSeH for excretion	Reactome Pathways 2024	1.0	null
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842624
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087548
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
Perturb_10322_KO_MYC_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.22891
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	2.04572
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
Perturb_960_KO_Psmc4_SRP173487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.16987
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48693
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.064978
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13797
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866549
BTK_knockout_2_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.170907
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27412
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863154
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.3036
UOK101	Achilles Cell Line Gene Essentiality Profiles	1.0	1.53456
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051061
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.022
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.40008
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051371
hsa-miR-296-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.30451
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29006
methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
GIMEN	DepMap CRISPR Gene Dependency	1.0	3.28043
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1075_KO_Il17a_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.67971
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1300_KO_Foxp1_SRP158103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.6982
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124135
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62811
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86076
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34257
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38795
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913126
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12313
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31939
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43436
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52853
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083238
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36905
SRY	ChEA Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
HMGN3_02_45	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.76377
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.22758
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44898
Perturb_11713_KO_Kpna3_ERP009054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874308
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970093
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69161
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30289
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872097
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.52821
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46597
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059429
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3973
Perturb_6028_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2825
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0293
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27584
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04343
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961699
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41875
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77056
A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.83174
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58871
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7123_KO_Prkcd_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.0004
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196139
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51495
intermediate stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32996
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98408
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0845
S-Adenosylmethionine	MW Enzyme Metabolite Associations	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22532
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064211
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12175
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357058
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.831
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50091
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
Retinitis pigmentosa 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
RAVE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bleomycin_mus musculus_gpl81_c57bl6j_gds251	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66135
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09728
JVE015	DepMap CRISPR Gene Dependency	1.0	3.27415
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34402
klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.073319
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
fh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.31
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069313
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Edema	CTD Gene-Disease Associations	1.0	1.6891
Perturb_10819_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.4831
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876389
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25287
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00888
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB4_02_64	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3012
subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998791
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08678
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12095_KD_Pten_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.18698
MPZL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62947
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.554367
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
High endothelial venule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
GMS10	CCLE Cell Line Gene Expression Profiles	1.0	1.36941
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96863
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7628
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.09846
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.37217
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09565
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30395
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947551
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19612
Perturb_11595_KD_CGAS_SRP107235	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.24776
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89859
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS274T	CCLE Cell Line Gene Expression Profiles	1.0	1.90654
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882186
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
PMC7591516-41467_2020_18955_MOESM6_ESM.xlsx-Overlap_DEGs_MSC_Diff_GCTB-Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCA4_02_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4804-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93384
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4004
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01315
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10236_KD_Kat7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.32791
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12252
Perturb_16080_KO_Myf6_SRP212302	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15362
Fatty Liver	CTD Gene-Disease Associations	1.0	1.94829
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19713
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21249
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24185
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01926
Perturb_11090_OE_Alr_SRP153001	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5938
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42087
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06363
spleen	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3525
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38726
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68901
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1936
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28935
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25761
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834205
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11077
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212488,GSE218420_1_v_2_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
glipizide_mus musculus_gpl81_gds1808	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047326
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
JUND	ENCODE Transcription Factor Targets	1.0	null
Dimethylsulfide	HMDB Metabolites of Enzymes	1.0	null
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72805
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18582
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857045
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22533
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.741
HS840T	CCLE Cell Line Gene Expression Profiles	1.0	1.75451
mitochondrion	LOCATE Curated Protein Localization Annotations	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4330	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16857
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09456
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02282
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18846
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061821
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17097
GSE212488,GSE218420_0_v_2_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2752
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.51657
Immunologic Deficiency Syndromes	CTD Gene-Disease Associations	1.0	1.01137
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090845
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105239
mantle zone of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09072
SQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89768
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855056
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78898
Hypertension	CTD Gene-Disease Associations	1.0	1.62379
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076064
Nanotubes, Carbon	CTD Gene-Chemical Interactions	1.0	null
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12661
Perturb_6370_KD_ETV1_SRP124661	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.04298
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.48556
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06154
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21001
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.85403
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02322
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.42511
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Memory T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.694
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S-Adenosylhomocysteine	HMDB Metabolites of Enzymes	1.0	null
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878409
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69422
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.65358
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868522
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE188599_11_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4417587__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_11654_KD_MCFP_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02906
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15408
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5536
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Airway fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18331
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.229
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18912
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21203
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45744
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal lymph node morphology	IMPC Knockout Mouse Phenotypes	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10830_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.64211
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841208
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17777_KO_Nr4a1_SRP158538	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.2737
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.971
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14408
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68344
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71621
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03227
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02724
SEM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74304
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13505
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2122
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12486367-Supplementary_Data2.pdf-353-EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39099
TRPM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77122
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27576
Tryptophan metabolism	KEGG Pathways 2026	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43928
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857534
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873995
Drug Hypersensitivity	CTD Gene-Disease Associations	1.0	1.13109
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09099
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27024
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47791
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07402
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.08248
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75378
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12777
GATA2_02_28	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.96963
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.14713
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942848
N-Methylserotonin	HMDB Metabolites of Enzymes	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29649
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878409
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24765
MAFK	ENCODE Transcription Factor Targets	1.0	null
HS675T	CCLE Cell Line Gene Expression Profiles	1.0	2.91754
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8924039-Table1.DOC-0-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37768
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	0.691275
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30669
HSF1_02_73	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.08746
Tryptophan metabolism(Mus musculus)	WikiPathways Pathways 2014	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4762-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02163
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
periventricular stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3883
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8866
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43676
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56044
ZNF395_02_69	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.05889
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49582
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48476
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40104
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14729
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00887
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981857
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARG-19884340-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01765
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1494
Perturb_16375_OE_Erap1_SRP265324	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.16077
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.319363
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.27688
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
94T778	DepMap CRISPR Gene Dependency	1.0	2.03885
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.971
FGFR1_drugactivation_149_GSE32316	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84635
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945813
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	5.74051
Lymphatic endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50416
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.763499
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17344
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.2898
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72188
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.5241
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20231
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
methionine-importing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66447
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18403
Lung adenocarcinoma_LUAD_TCGA-49-6744-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19694
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67658
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957524
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36407
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869782
Anemia	CTD Gene-Disease Associations	1.0	1.10665
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
GSE90754_0_v_1_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Table_S2_List_of_TAL1_UTX_co-bound_genes_in_Jurkat_cells_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_2_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04254
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09921
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68111
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1296
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51839
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9948
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066474
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disorders of Sex Development	CTD Gene-Disease Associations	1.0	1.5382
Perturb_11739_KO_Nrf2_SRP108108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.77594
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRX-20693478-ADULT-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.09471
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21015
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22026
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079835
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95771
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07745
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61841
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05911
NB1643	DepMap CRISPR Gene Dependency	1.0	3.17784
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881952
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08294
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22397
ESR1-17901129-mouse liver-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KMRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58936
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987848
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03228
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48353
CRX	ChEA Transcription Factor Targets	1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.4012
MOLM13	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57632
Perturb_11238_KO_Trp53_SRP322469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.39654
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.308
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35288
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depersonalization disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
NUP93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31976
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.21468
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095476
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58798
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09717
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.086
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cecal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.859771
Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77341
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934376
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-PC-A5DO-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91007
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-38-ZNF507_ZNF507	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13173
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82492
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857412
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26284
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106121
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11705
Perturb_10796_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.02336
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0135
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07681
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Megacolon	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1_01_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.11103
PMC12606276-41698_2025_1121_MOESM1_ESM.pdf-30-CSRNP1_CSRNP1	Rummagene Transcription Factor Associations 2026	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07381
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.971
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51266
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76562
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35041
caco2	HPA Cell Line Gene Expression Profiles	1.0	2.1301
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1179
Acetaminophen	CTD Gene-Chemical Interactions	1.0	null
FOXK2_02_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.64386
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13165
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10737
DROSHA	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4768-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HS571T	CCLE Cell Line Gene Expression Profiles	1.0	1.9841
Perturb_10818_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.3193
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.75
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17847
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PMC4782046-supp_30.5.508_TableS2.xlsx-TAL1_UTX-co-bound_genes-Unnamed_4_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11223_KO_Mkrn1_SRP149173	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.5643
Perturb_10842_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.95245
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929264
hsa-miR-613	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_18122_KO_Bmal1_SRP068418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55654
Proximal tubule cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6776-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SET2	DepMap CRISPR Gene Dependency	1.0	2.22783
GSE174383_2_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_6053_KD_PRMT1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.22209
Perturb_10831_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.10371
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16502
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09565
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855863
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2099
NR2F2_02_19	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.95936
HNT34	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17747
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31762
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915227
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34964
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.02596
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872876
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893575
PMC7933006__F2	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11147
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2541
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11068_KO_Dnajb9_SRP097622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.48186
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.66932
CLOCK	ChEA Transcription Factor Targets	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87714
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.23744
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12766
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44751
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044881
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09909
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050681
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47749
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00928
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.04077
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1494
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04304
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20946
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07404
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01155
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43077
Perturb_6060_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43143
Perturb_10823_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31341
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09732
Perturb_10936_KO_Oxr1a_SRP102450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.86554
ethinyl estradiol_mus musculus_gpl75_gds285	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23711
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13165
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.95
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34652
p93	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
Intramolecular phosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.62437
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50474
15845616-Table4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32575
A-CA-04-2009(H1N1)_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.39909
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.04097
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34743
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23264
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31384
PMC12119775-13402_2024_1033_MOESM1_ESM.pdf-38-ENSG00000168813_ZNF507	Rummagene Transcription Factor Associations 2026	1.0	null
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46789
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cytosolic creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
Perturb_10261_KO_Esrrg_SRP119935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.49616
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.6714
myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249664
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16891
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
prednisolone_mus musculus_gpl1261_gse21048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51606
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12187
PMC7863452-12920_2021_883_MOESM6_ESM.xls-SRG_13_GE2-HCC_vs_10_GE1-HCC-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
Drug Eruptions	CTD Gene-Disease Associations	1.0	1.03604
CLOCK-20551151-293T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.3443
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.40232
Perturb_6039_KD_MRTO4_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.50728
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	2.30819
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987848
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11951
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11607_KD_ASB15_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83725
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50461
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Death	CTD Gene-Disease Associations	1.0	1.11673
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4703-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3351_KO_Tsc2_SRP227934	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.301
Selenoamino acid metabolism	Reactome Pathways 2024	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	5.29123
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
N-methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23444
S-adenosylmethionine-dependent methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
Perturb_5695_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13463
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6921
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26147
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16315
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-453-HIC2_HIC2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99152
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94734
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00269
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079088
Pericellular basket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16493
Prostate small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
liminal part of alar isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11464
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.86407
pbmc cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482817
T24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1025
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00961
GSE206779_1_v_3_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
hsa-miR-3667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13034
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRF	MotifMap Predicted Transcription Factor Targets	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
sevoflurane_homo sapiens_gpl570_gds2772	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2009	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10468
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54254
Perturb_8504_KO_Hr_SRP200420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.71468
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0247
CITED2_02_38	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.34577
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02017
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40617
endoplasmic reticulum	LOCATE Curated Protein Localization Annotations	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ROS50	DepMap CRISPR Gene Dependency	1.0	9.02811
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03259
SKGT2	DepMap CRISPR Gene Dependency	1.0	8.95786
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47634
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19129
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4353
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11529
ERBB2_knockdown_238_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.77232
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13709
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832113
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043826
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35542
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.1724
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7437
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949585
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10833_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57462
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05278
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00371
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78185
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14292
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.37876
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52783
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12843
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6205
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0092
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transferase activity, transferring one-carbon groups	GO Molecular Function Annotations 2015	1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.43428
hsa-miR-1268b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825578
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825378
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28853
myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122376
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
DAOY	DepMap CRISPR Gene Dependency	1.0	3.64184
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922909
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02226
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0309
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15169
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42945
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.512
Stevens-Johnson Syndrome	CTD Gene-Disease Associations	1.0	1.10803
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.21695
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08055
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0594
Perturb_16940_KO_Nr4a1_SRP158538	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.68497
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.662742
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05687
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3968
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058454
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12971
hsa-miR-3665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Infertility, Male	CTD Gene-Disease Associations	1.0	1.47915
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44377
nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948518
Metabolism of amino acids and derivatives	Reactome Pathways 2024	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64227
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88124
PPARG	ChEA Transcription Factor Targets	1.0	null
JUND_02_16	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.22239
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64713
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25882
Perturb_12086_OE_Esr1_SRP050547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0334
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A199-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.3639
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3767
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.36876
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68212
ES8	DepMap CRISPR Gene Dependency	1.0	3.29288
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMCH1	DepMap CRISPR Gene Dependency	1.0	4.98171
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	8.70623
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13632
PMC4468904__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972618
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00673
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886727
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07418
Perturb_11160_KO_Atp7b_SRP100615	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93866
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.794
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33001
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964107
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.02975
Sarcoma_SARC_TCGA-X9-A973-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55853
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60253
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
DANG	DepMap CRISPR Gene Dependency	1.0	2.00518
Cholestasis	CTD Gene-Disease Associations	1.0	1.21435
PMC7278058__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9565
Heart Diseases	CTD Gene-Disease Associations	1.0	1.29103
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19124
PMC4686057-pone.0145107.s001.xlsx-CAA-C-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
titanium dioxide_mus musculus_gpl1261_non-pregnant_gds2878	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPA	ChEA Transcription Factor Targets	1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3976
GSE149075_2_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869713
PMC12520974-44161_2025_709_MOESM2_ESM.xlsx-Extended_Data_Fig_4a-Extended_Data_Fig_4a_Marker_genes_used_in_the_heatmap_for_ATF3_4_Capillary_and_Venous_in_non-ischemic_vs_PAD_comparison_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05904
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7146
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058316
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DROSHA-22980978-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00176
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62379
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827941
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.2152
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44982
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39883
GSE157904_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044776
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98021
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70414
Fumarate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.715
Perturb_6534_KD_Cd80_SRP338134	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10320_KO_HDAC1/HDAC2_SRP255858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.52598
rosiglitazone_mus musculus_gpl1261_gse11343	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905346
Perturb_12317_KD_HNRNPM_SRP136770	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.56356
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26441
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10529
S-adenosyl-L-methionine-dependent methyltransferase	InterPro Predicted Protein Domain Annotations	1.0	null
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87837
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11757
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36749
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
Perturb_11186_KO_Gdown1_SRP244620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.92857
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rosiglitazone_mus musculus_gpl81_gds1808	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20324
Perturb_16363_KO_Cryab/Hspb2_SRP055864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71413
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8127234-12885_2021_8319_MOESM2_ESM.docx-0-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050439
Perturb_10832_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.25172
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5444
Pain	CTD Gene-Disease Associations	1.0	1.3931
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1821
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03609
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42489
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.104
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.48879
Metabolism	Reactome Pathways 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6356_KO_Bcat2_SRP058363	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.74804
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41886
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46625
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41619
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36616
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.70044
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.31297
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18166
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44141
GB-93-CC27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200272
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SNUC4	DepMap CRISPR Gene Dependency	1.0	2.09133
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236072,GSE236075_2_v_0_ccr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11108_KO_Cpt2/Ppara_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.44647
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920231
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29649
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01864
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0431
SPRYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93376
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78829
CEBPA-23403033-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KYSE270	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10222
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975058
hsa-miR-4704-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13394
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53465
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11792
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886777
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71689
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4951
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08892
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cyclosporine	CTD Gene-Chemical Interactions	1.0	null
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.26266
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5-Hydroxyindoleacetaldehyde	HMDB Metabolites of Enzymes	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14573
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01565
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4661-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044056
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0126-SM-4GIC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945835
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40148
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17502
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07085
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nephrolithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.971
Perturb_11240_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.41399
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46226
binding	GO Molecular Function Annotations 2015	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
CTBP1_02_41	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
20937356-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4684
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.69341
DMS273	CCLE Cell Line Gene CNV Profiles	1.0	2.9221
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18396
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-602	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37347
Lung Injury	CTD Gene-Disease Associations	1.0	1.09541
SNU398	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75525
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3499
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.087
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF644	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24152
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11839
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052773
KP2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05092
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45488
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32167
methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53771
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07449
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.3231
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02308
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.656972
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4818
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90722
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12321
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06571
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060478
PMC7347220__F5	PFOCR Pathway Figure Associations 2023	1.0	null
S-Adenosylmethionine	HMDB Metabolites of Enzymes	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00805
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9752
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07175
Fibrosis	CTD Gene-Disease Associations	1.0	1.86672
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9988762-43032_2022_1002_MOESM1_ESM.xlsx-Integrate_DEGs_PGR_Gain_Site-Gene_Symbol_PGR	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.71537
Uterine Neoplasms	CTD Gene-Disease Associations	1.0	1.1294
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06634
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19832
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
PMC6096065__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83143
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.34021
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OAW42	Achilles Cell Line Gene Essentiality Profiles	1.0	2.84655
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0859
Perturb_11114_KO_Gps2_SRP140448	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11306
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27934
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847862
Perturb_5521_KD_Apoa4_SRP393880	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11398
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992437
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66653
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_24_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07922
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34562
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08337
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.26793
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Prolactinoma	CTD Gene-Disease Associations	1.0	1.09083
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830352
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12979
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19038
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE250230_1_v_3_gramd1c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.71799
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
RARG-19884340-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.33316
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051633
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.40335
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982971
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0214
Bladder Urothelial Carcinoma_BLCA_TCGA-SY-A9G0-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10856_KO_Shp_SRP220815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75367
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5561
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13477
Carcinoma	CTD Gene-Disease Associations	1.0	1.11843
Brain Injuries	CTD Gene-Disease Associations	1.0	1.09963
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04249
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0526-SM-4DXTH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842337
Perturb_10828_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.15126
MYC	ChEA Transcription Factor Targets	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7278058__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97051
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66212
Perturb_10897_KO_Nr5a2_SRP131036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.18101
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06138
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69893
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860333
HLFA	CCLE Cell Line Gene Expression Profiles	1.0	2.19403
s-adenosylmethionine-dependent methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-1	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054162
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3689d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308867
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6017
response to toxic substance	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14557
lung	GTEx Tissue Gene Expression Profiles	1.0	2.00961
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90082
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10939_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60725
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C33A	DepMap CRISPR Gene Dependency	1.0	8.65373
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.933211
KMS18	DepMap CRISPR Gene Dependency	1.0	2.43346
methionine-importing ABC transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920232
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10843_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.48962
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24017
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09199
GATA1-22025678-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830356
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876732
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978842
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03169
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2644
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.22696
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907084
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80767
HS172T	CCLE Cell Line Gene Expression Profiles	1.0	2.75955
Perturb_10824_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.65269
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043573
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76465
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86141
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Proteasome activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935834
Perturb_17239_KD_PDCD10_SRP389914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.99848
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0626-SM-48TZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04924
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945919
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856389
Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
myoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149653
FBXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84652
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.56448
Medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41819
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10877
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.106898
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.72905
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01824
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71484
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75245
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03483
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137144_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905488
amine metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10841_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.6635
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47001
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936663
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	ChEA Transcription Factor Targets	1.0	null
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04249
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916192
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0972
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.83007
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81306
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17132
pioglitazone_mus musculus_gpl1261_gds4413	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
N-Methyltryptamine	HMDB Metabolites of Enzymes	1.0	null
HS618T	CCLE Cell Line Gene Expression Profiles	1.0	1.58943
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832583
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03516
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39723
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21279
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35169
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.21337
Porphyria Cutanea Tarda	CTD Gene-Disease Associations	1.0	1.01776
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.96191
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0017
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079187
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE151160_0_v_1_cd36_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thioether s-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14271
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09159
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.32074
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7713
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48446
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51531
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28239
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
Urolithiasis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12235
647V	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77111
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1914	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59603
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37706
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
locus coeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29597
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39082
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.887648
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051062
GSE165548_2_v_1_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
Perturb_10326_KO_Shp1_SRP370028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53907
Perturb_11328_KO_Nr1d1_ERP109959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43956
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Perturb_6074_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.81048
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957825
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6026_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.86916
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87448
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85282
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r6 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03101
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
NCIH2126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62184
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
niacin_mus musculus_gpl1261_gds2605	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47341
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82409
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.37871
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19333
XB-70-NK42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.527471
lateral part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09264
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861373
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.40498
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849329
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.756994
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14317
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC6733950-41598_2019_49548_MOESM7_ESM.xlsx-lncrna_deg_gtf_closest_genes_fd-HIVEP2_HIVEP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06824
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05368
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060013
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111035,GSE111040_10_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061617
SNU-61	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74122
response to chemical	GO Biological Process Annotations 2015	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	2.67473
MET_knockout_250_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82531
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16822
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29136
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.9516
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.16633
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5277
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6073_KD_SUV39H1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.42315
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26437
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amine N-methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4332
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_14215_KO_Psen2_SRP254653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.80118
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00682
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01646
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70501
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945813
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36999
PMC7734567__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TEDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20743
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46328
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.208742
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24578
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A1-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31243
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48594
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61035
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32393
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27846
hsa-miR-596	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
Vgamma9Vdelta2 T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68381
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06742
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.70506
TAL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22452
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17132
WM793	CCLE Cell Line Gene CNV Profiles	1.0	1.53412
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53412
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44973
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82451
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.14704
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7947
Nephrolithiasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06844
Perturb_10825_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79361
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25523
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855054
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74269
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44274
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79752
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6429
Perturb_10817_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96934
GSE165074_0_v_1_fam114a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system_CT1_alveolar type 1 fibroblast cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34297
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_18151_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.44717
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51529
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dizziness	CTD Gene-Disease Associations	1.0	1.25899
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
Perturb_10906_KO_Xbp1_SRP051964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837035
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-157-NFE2L3_NFE2L3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902542
hsa-miR-3160-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
THAP1_02_46	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.27302
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7254-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86776
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81861
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.39232
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179324
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89873
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49567
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.028
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18734
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75851
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859816
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72701
Meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
20630075-AF-3	GeneSigDB Published Gene Signatures	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0477
RPMI7951	CCLE Cell Line Gene Expression Profiles	1.0	2.17801
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17864
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32307
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52618
TMEM88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25564
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28161
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08046
N-Methylserotonin	MW Enzyme Metabolite Associations	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852444
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831336
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
PMC9160255-41467_2022_30710_MOESM5_ESM.xlsx-AR-targeted_enhancer_peaks_anno-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36502
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1795
Liver	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.047
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06317
PMC4417587__F1	PFOCR Pathway Figure Associations 2023	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27076
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73818
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
PANC0327	DepMap CRISPR Gene Dependency	1.0	3.16543
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998888
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897573
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29019
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81009
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26324
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27889
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82135
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.03235
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83075
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18172
CHLA15	DepMap CRISPR Gene Dependency	1.0	2.41196
Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944679
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22559
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.11934
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.841
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.93233
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
20421987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.35138
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28683
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47155
Selenocompound metabolism	KEGG Pathways 2026	1.0	null
PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0543
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75857
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901148
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36396
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60274
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.11673
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
Heart endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.42237
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7243
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87341
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811056
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20333
Perturb_11270_KO_Bmal1_SRP337469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38985
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63179
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6043_KD_NCOA5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.041
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15845616-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GB1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04768
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-RM2N-1126-SM-48FCY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826402
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06013
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80593
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857314
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Integral component of presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.82
S-adenosylmethionine-dependent methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
MV411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.80576
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71745
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5158
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157049,GSE157051_6_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD4_druginhibition_224_GSE50865	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.14532
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28656
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48612
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0036
skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
12734205-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A627-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SARS-CoV MA15_Day4-TNFRsf1b KO_None_GSE40824	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31467
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hirschsprung Disease	DisGeNET Gene-Disease Associations	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53047
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10646
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912161
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38134
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22112
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.51406
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971824
N-methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Hot Flashes	CTD Gene-Disease Associations	1.0	1.02336
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163317
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_mus musculus_gpl81_gds250	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977718
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.88075
Methyltransferase NNMT/PNMT/TEMT, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A6BE-01A-41R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung-alveolar fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0432433
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03997
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17873912-Table1	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24022
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44317
Lipomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.25676
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62918
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mt-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17935
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18725
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01979
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13767
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78453
UACC62	CCLE Cell Line Gene Expression Profiles	1.0	1.50137
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914874
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07155
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23978
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.126
PMC6469946-aav1472_Data_file_S3.xlsx-PPARG_targets_UP_RNA-Seq_Diet-Supplemental_Table_3_PPARG_targets_up_regulated_in_dKO_vs_CONTROL_RNA-Seq_Diet_FDR_0_1_n_290_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11374
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67484
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31328
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Calcium oxalate nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05803
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28657
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84709
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223177
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6B-Table_S6B_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_Type_II_LGG_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.27716
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11646
Perturb_11854_KO_Fosl2_SRP131329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.70097
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058967
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4736	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Perturb_4494_KO_Ccr8_SRP293026	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.52973
Perturb_11747_KO_Mek2_SRP321493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8109
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.83538
UBTF	ENCODE Transcription Factor Targets	1.0	null
PMC6756575__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20469
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW48	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45664
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69073
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39618
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21086
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64227
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20577
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.860261
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57253
PMC7933006__F2	PFOCR Pathway Figure Associations 2023	1.0	null
UBXN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54147
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03989
Perturb_11610_KD_BPIL1_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.13479
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60759
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE-280	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84372
improved glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20484
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17921
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11171
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44888
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09449
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11496
L-Methionine	HMDB Metabolites of Enzymes	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5092
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150216
RS5	CCLE Cell Line Gene Expression Profiles	1.0	2.40872
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17561
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	4.63131
Perturb_11075_KO_Rictor_SRP097622	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.04946
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5153
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11494_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39164
Tunica externa vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051937
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08917
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
hsa-miR-1251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059681
PMC10338540-41416_2023_2282_MOESM2_ESM.xlsx-AA_metabolism-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98408
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3344
Left nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
MIAPACA2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02421
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10835
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23307
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32516
hyperhomocysteinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.494266
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
COL1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22639
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941292
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8531
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18359
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04789
GATA1	ChEA Transcription Factor Targets	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-386-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58904
Perturb_11265_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.00717
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
PMC7734567__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.61245
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38179
t59-kidney_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-4.69486
Perturb_8418_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.44421
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.10527
s-methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
BBm cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
Phosphomannomutase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07961
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40874
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serotonin	MW Enzyme Metabolite Associations	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JP8 aviation fuel	CTD Gene-Chemical Interactions	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46272
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.532
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSB_FOSB	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75247
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3392
Perturb_10844_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.7081
GSE227415_1_v_0_ucp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS294T	CCLE Cell Line Gene Expression Profiles	1.0	1.45306
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.835
Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ChEA Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97222
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.931049
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11125_KO_Stab1_SRP149099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.9661
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39038
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1821
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44633
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37178
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9165
Peyer's gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17132
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
PMC12092893-12672_2025_2715_MOESM1_ESM.pdf-7-TCF23_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	2.14378
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vasculature-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	11.7129
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49748
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81098
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44748
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04551
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51704
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7399
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.59774
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896887
PMC6096065__F6	PFOCR Pathway Figure Associations 2023	1.0	null
PMC12120721-ADVS-12-2411752-s001.xlsx-Data_S23-Data_S23_DEGs_between_ESR1_SMC_ecotypes_and_DES_SMC_ecotypes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62909
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
Hypertriglyceridemia	CTD Gene-Disease Associations	1.0	1.10211
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47126
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7908
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938334
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879607
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18707
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95209
MXD3_02_83	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.58496
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.59653
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898721
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.37018
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40189
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37989
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00249
A_CA_04_2009_4dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.30206
Perturb_8874_OE_TCF21_SRP081577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC11968629-12672_2025_2184_MOESM1_ESM.pdf-2-ETV1_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11166_KO_Tak1_SRP149497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07493
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OUMS23	CCLE Cell Line Gene Expression Profiles	1.0	1.55392
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5241
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77835
hsa-miR-4645-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65396
Perturb_13052_KO_Il17a_SRP268747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64978
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
methyltransferase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87047
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30177
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96386
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3057
Hypospadias	CTD Gene-Disease Associations	1.0	1.47322
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05066
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0952
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skeletal muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mantle zone of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11333
Perturb_10916_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.18612
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4907
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102275
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1887
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950345
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6758
Liver Diseases	CTD Gene-Disease Associations	1.0	1.90492
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03066
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anorexia	CTD Gene-Disease Associations	1.0	1.09262
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51274
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62981
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.75864
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98408
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11879
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27055
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06463
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967976
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889933
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28357
P31FUJ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28623
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1915	DepMap CRISPR Gene Dependency	1.0	2.10117
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11622
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Perturb_10829_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.29991
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.44001
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59292
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-206	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PMC9086029__F6	PFOCR Pathway Figure Associations 2024	1.0	null
CEBPA-23403033-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
PMC10831540-supplementary_table_1.xlsx-DEG_pc-S-EC2-Unnamed_8_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43533
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75619
15902281-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12738
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92653
8305C	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4766
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38551
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.453
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.3414
Proteinuria	CTD Gene-Disease Associations	1.0	1.34518
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17983
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18477
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Perturb_11203_KO_Mettl3_SRP322470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.9636
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Trimethylselenonium	HMDB Metabolites of Enzymes	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YW-3026-SM-3MJHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02021
Schwalie et al.Nature.P3_Adipose tissue_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940745
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945813
NB10	DepMap CRISPR Gene Dependency	1.0	3.41201
Infertility, Female	CTD Gene-Disease Associations	1.0	1.37676
Perturb_11131_KO_Yap1_SRP281955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.94267
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.9591
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.29393
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100580_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12552
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06671
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926931
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.47614
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9889
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861154
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850212
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Myc-CaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9462
vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04704
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84166
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27644
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	2.92054
Heart-fibroblast of cardiac tissue	Tabula Sapiens Gene-Cell Associations	1.0	0.439959
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12865
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.17132
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30865
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916726
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32446
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59855
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88429
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dexamethasone_mus musculus_gpl339_gds2314	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50342
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1767
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null