association	dataset	threshold value	standardized value
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03484
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346699
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22317
PMC12079334-ADVS-12-2501734-s002.pdf-149-ENSG00000180357_ZNF609	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40804250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95094
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB-06-WW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333044
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5632
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.83518
BRD-K62572662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05291
merck-ketone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00834
BRD-K76210487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11299
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.38514
5564_NDUFC2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.539284
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16647
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2449
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57081
BRD-K12593465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16126
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
BRD-K83949633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96493
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00754
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24006
BRD-K03265347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38605
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.90085
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317326
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805097
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.87564
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.0788
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379814
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.20281
BRD-K13844473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14942
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164998
BRD-K94862255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23161
BRD-K64836560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77424
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24322
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_8_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06203
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30628
BRD-K50600207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01256
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.603589
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.760852
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00286
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07906
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79753227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15747
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
BRD-K98961458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66355
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06575
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67115
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0239
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7011
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4643
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51643438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31106
GSE57871_8_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.067
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397665
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191694
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06996
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.96348
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348374
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0759
BRD-K36198653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14489
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K25423143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07526
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12574
PMC12289921-41467_2025_62099_MOESM5_ESM.xlsx-MI-2-80-Gene_Symbol_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE250089_0_v_3_epcam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23963854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12615
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73351
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8963
BD-69-XG81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278454
BRD-A94420133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85271
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36815
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62263376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47362
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160654
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01602
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	1.0	null
Integrator complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PHF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39432
6351_PIK3C2A_ENST00000265970.7	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.631733
MAPK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41667
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7754
EFM19_BREAST	CCLE Cell Line Proteomics	1.0	3.5585
BRD-K75806288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24191
BRD-K81574470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74732
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63984483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0649
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53795
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414828
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00499
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.57545
BRD-K87230984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5913
BRD-K85500722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19147
CF-97-AV07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423135
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10384
EB-67-WB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.537206
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6873
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.26905
PMC10960568-mjad044_supplemental_file.pdf-38-HES1_HES1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24043
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.17207
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73719
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268774
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.15812
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60057192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28561
BRD-K87790666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29479
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4122
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352297
BRD-K52054012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26219
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1187_BREAST	CCLE Cell Line Proteomics	1.0	2.1151
BRD-K18189580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.192
NE-20-WM78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.7244
BRD-K58194737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34938
HC-76-HU27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442981
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	14.8656
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74019
Myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67693903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91216
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426986
KDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38339
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09768
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3834
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45014
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348537
BRD-K54621976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07583
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07366
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4591
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2735
BRD-K19245310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26657
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.919883
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.58415
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399554
BRD-K13761649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10155
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.82208
BRD-K07794261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39074
DA-27-BW40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228733
CRCGN016_MCF10A.TP53.M_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07646
BRD-K98086832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3199
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K20831543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44958
Nuclear exosome targeting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	4.61138
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210478
MF-11-EW49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316535
BRD-K28720546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13604
RA-49-ZB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265625
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0642
MCF7_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143295
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33756
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
BRD-K16915521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09699
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
BRD-K90366266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27712
RPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20653
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17841
BRD-K03371288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87974
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02823
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PECAPJ34CLONEC12_UPPER_AERODIGESTIVE_TRACT	CCLE Cell Line Proteomics	1.0	2.86249
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28762
nizatidin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41794
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_5_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337471
KARPAS-422 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96759
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69754
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29760532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05199
EA-40-KQ08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420377
snRNA metabolic process	GO Biological Process Annotations 2025	1.0	null
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68798
BRD-A47963183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70106
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04918285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00476
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213611_1_v_0_nuf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.968
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.93047
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01279
1381_CD99L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654339
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39277
GSE57871_8_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20185
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14787
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48372
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09803
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92838
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258509
CRCGN015_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0434
AC-55-XA97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830763
CRCGN017_MCF10A.TP53.M_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00794
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90255725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11184
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6474
regulation of DNA-templated transcription elongation	GO Biological Process Annotations 2023	1.0	null
TB-06-VB30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206598
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20595
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00247
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9951
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80940089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29192
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308745
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
4108_IMP4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515141
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73635724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51385
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455601
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240444_2_v_3_idasanutlin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549621
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN008_HEPG2_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09975
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342497
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130946
PMC9675280-12950_2022_317_MOESM3_ESM.xlsx-siPAD2_LPS_vs_siCON_LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14688
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10758
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5513
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08878
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87580376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1239
CRCGN016_MCF10A.WT.HP_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01659
BD-93-AM31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234627
BRD-K47748211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08145
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.959593
SOSS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.45
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
snRNA processing	GO Biological Process Annotations 2025	1.0	null
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145174
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.23467
BRD-K36134372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47385
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339319
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0855
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K83028309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06751
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:D21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5461
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47842
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1781
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57522
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7355
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49215099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41299
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338242
BRD-K45537529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70314
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.36057
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42754852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10676
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47626
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.828
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.93291
BRD-A22089150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43065
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.9107
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22552
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22564762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42146
AF-80-GK24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.61758
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20677
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410975
BRD-K37328981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09629
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.30492
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.054
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10483
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.92762
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
BRD-K62795540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02935
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K40697889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.536
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21868
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.556445
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06911479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25445
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	11.3926
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.60675
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33479
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.627
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.939643
GSE135350_3_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27935
BRD-K32476586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09618
BRD-K24243182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20871
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3728595-srep02327-s1.pdf-17-POU2F2_POU2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Feather calamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.29115
BRD-K57472585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3284
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25065
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5384
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0612
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569421
BRD-K55853030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26368
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81456
BRD-K90040724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32236
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19908
GSE186810,GSE186813_2_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23306
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1545
BRD-K53110645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64399
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01154
BRD-K66299486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5085
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
BE-69-RD44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.570737
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.5967
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251961
CRCGN015_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0934
BRD-K75311902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99328
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4751
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275312
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34809
BRD-K14359826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4272
PMC12347849-mmc1.pdf-25-ENSG00000096401_CDC5L	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10728
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01352
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363752
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28347985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37375
BRD-K50474387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33481
Bile duct carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-up_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
DSIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.839
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4689
BRD-K23840704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31826
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3446
CRCGN017_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0665
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16238
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A80081229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18935
CRCGN017_MCF10A.TP53.M_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23215
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57209
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82671459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09403
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280492
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12295
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34164
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13385
BRD-K86288396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09139
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299308
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.554615
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40163
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.557183
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44252
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13524
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01726
BRD-K64451677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30318
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BB-55-JH29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221716
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5729
EE-23-MF14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214277
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56939
BRD-K42558179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26825
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20049
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNA polymerase II, holoenzyme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.94
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrion	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44944875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36094
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PC-62-AQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.872449
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Promyelocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
BRD-K32362211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95764
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30893
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.878212
BRD-K24752397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49452
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.089
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57495
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2688
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2664
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.52276
RNA polymerase II transcribes snRNA genes	Reactome Pathways 2024	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.43616
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29013
Mr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
4651_LRP8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.815182
BRD-K64194889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03279
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26182
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.66335
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DA-10-HD17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22919
BRD-K73831263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00893
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.00732
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98374711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56826
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35381
DF-84-RT50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226409
BRD-K69438930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19272
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22599787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07723
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06388
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08392
GSE231799_2_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6326
snRNA 3'-end processing	GO Biological Process Annotations 2025	1.0	null
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97641
Corpuscular Hemoglobin Concentration Mean	DisGeNET Gene-Phenotype Associations	1.0	null
GTEx Thyroid 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.7113
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00098
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07311
CRCGN017_MCF10A.WT.HP_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6079
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365338
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310798
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39601
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.56309
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664041
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16239
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K09376957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31559
BRD-K34985200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99728
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49405
cyclin/CDK positive transcription elongation factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
BRD-U02532950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91012
GSE149943_2_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-72-JP86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222572
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01355
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229294
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01625
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1723
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03001
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3065
AB-17-WP43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202155
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10238
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26266
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23845
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352665
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311661
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8875
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52708
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92215
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.835
BRD-K11687039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77818
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0769
1p36 copy number variation syndrome	WikiPathways Pathways 2024	1.0	null
PMC4729482-pone.0146505.s001.xlsx-Sheet1-chRCC_positively_associated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241004
P-TEFb complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.257
BRD-K12571248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2935
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502381
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62620616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11397
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3888
BRD-K72463020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08453
BRD-K94962273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02402
BRD-K09900382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03265
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13829
BRD-K86545229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08098
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.72184
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38865
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
DMS273_LUNG	CCLE Cell Line Proteomics	1.0	5.8073
BRD-K61595867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11998
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85629
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42804674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24671
BRD-K59399000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11373
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3384
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29429
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18188
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.78921
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.601829
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.613209
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61316494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21135
BRD-K52735829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72876
BRD-K05777604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64425
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9962
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245244
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14501
CRCGN015_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02295
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64593
K562_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154486
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.84154
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.68475
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_9_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36537572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08386
CRCGN017_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64964
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.23495
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64537
BRD-K26393435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02746
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325213
BRD-A59682351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29738
BRD-K04317371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2308
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26543702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22517
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K04366109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09791
Nuclear cyclin-dependent protein kinase holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05504
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78984
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15353
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K84514454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09548
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.86651
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75999096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00003
BRD-K76197651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08849
CRCGN015_MCF10A.TP53.M_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11459
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08239
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.629411
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.983
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1944
GSE182680,GSE182683_5_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40001470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35591
BRD-A14331394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50724
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43543979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0277
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21269
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0939
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95500860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60616
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32911
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72239
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3224
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540323
BRD-K54872884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32678
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257721
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44295
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73497584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60088
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35462787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50598
Hyaline body myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
496100415_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20803
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.758
GSE92589_0_v_1_sirolimus_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.80635
BRD-K63299069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63369
BRD-K34677894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11201
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27186
BRD-K30199352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54926
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34739404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11587
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5840266-41598_2018_22384_MOESM13_ESM.xlsx-UBR7_KD_significant-Unnamed_23_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94742710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2197
BRD-K24525269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29709
BRD-K97247086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41653
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24198
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UE-90-AA63_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230912
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.59594
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07927
OF-05-CB18_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460716
CRCGN015_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15954
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9487
1-EBIO	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02727
BRD-K53104784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03727
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-9.51651
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.31212
CRCGN016_MCF10A.TP53.M_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15578
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32843
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22385
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0343
10163_ZNF131_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.715483
Cholangiocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72145393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32653
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNA 3'-end processing	GO Biological Process Annotations 2025	1.0	null
ERVMER34-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01094
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1107
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12723
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71022
BRD-K00502656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75398
BRD-K20440082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54029
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1942
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.841065
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37842
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bile duct adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319162
BRD-K53458780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89205
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12635
GE-22-ME44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224913
BRD-K32839286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32122
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23252
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317165
BRD-A06232236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82291
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44749
ncRNA processing	GO Biological Process Annotations 2023	1.0	null
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51399866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04375
BRD-K55795421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06798
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409444
MCF7_Ramelteon_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177243
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60869
A549_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136841
A549_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150878
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.06849
BRD-K04725393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01461
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19176
HEK-293F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39579
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25789
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507014
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0071
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5542
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K35480932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81555
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14923
BRD-K44834268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05852
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00908
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80630598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53771
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72475
BRD-K71357636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3781
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.62092
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19609
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11880379-41467_2025_57480_MOESM3_ESM.xlsx-SOX9_RIME_Limma-Gene_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62582
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.33925
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38687
CRCGN016_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.54934
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553474
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2497
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.68075
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0731
Cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
BRD-K11258719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69422
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.58942
CAKI2_KIDNEY	CCLE Cell Line Proteomics	1.0	3.85017
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27298
GSE153871_0_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44224
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.52383
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNA processing	GO Biological Process Annotations 2025	1.0	null
BRD-K01827055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0427
BRD-K24382357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45144
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.840261
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.011392
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59821747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25836
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.257
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.82538
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.61737
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9316
BRD-K01717817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27802
BRD-K06116445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63969
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.796561
PMC10591418-12711_2023_849_MOESM11_ESM.xls-AA_5W_vs_LS_5W-gene_name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1437
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254404
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86586698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20428
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68856
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.04459
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38896
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.885
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-5.96226
Organellar large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370883
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
i10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312064
BRD-K81006490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3146
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7387
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00223
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247046
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36858
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.555293
BRD-K20253608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33316
8905_TIFA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.529133
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-26-RY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277988
BRD-K94049419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01082
BRD-K81266242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42792
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
7275_RGS14_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.504675
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.907
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00525
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65311
CRCGN017_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61975
BRD-K56075657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12461
CRCGN015_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24855
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A63503250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32318
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2552
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.76428
BRD-K14520048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43538
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.426896
PMC8160578-JCB_202009147_TableS4.xlsx-FOXM1_targets-Genes_n_696_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24425
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80098154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54636
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04228
BRD-K13534347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94649
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46586
CLDN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77896
BRD-K93874059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55135
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42943023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13195
BRD-A99990159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54284
BRD-K29969800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6311
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02955
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309156
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13571
Organelle membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
CRCGN017_MCF10A.TP53.M_24H:E05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61022
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78597
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.05851
Mitochondrial large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5552
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.11177
regulation of transcription elongation by RNA polymerase II	GO Biological Process Annotations 2025	1.0	null
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59157
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00053
BRD-K70357895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10987
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26508889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31098
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48142
C12orf57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66389
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337962
Nemaline myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
NB-12-ZK38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402553
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12260863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16712
CRCGN015_MCF10A.TP53.M_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15345
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12304
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05361
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33234
NCIH1581_LUNG	CCLE Cell Line Proteomics	1.0	2.69771
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374593
Feather rachis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
regulation of transcription elongation by RNA polymerase II	GO Biological Process Annotations 2023	1.0	null
K562_PF-573228_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178481
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30281
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4779
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.9061
BRD-K17303020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10798
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9894
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	8.34439
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.057
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.881
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262623
BRD-K81031146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.061
TB-06-VB30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264331
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.609293
BRD-K68492420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05066
BRD-K47254434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22064
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26059
BRD-K47620421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09334
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial function and metabolism regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BRD-K21969044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19517
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89830699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09615
MCF7_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171497
Hybridoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28117
GTEx Brain 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	9.26996
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509162
Endomembrane system	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82517280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34486
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.90104
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69484
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04248
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34435
nucleus	GO Cellular Component Annotations 2023	1.0	null
GSE146982_3_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93537437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18973
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23681
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47535493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18318
BRD-K05096562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19556
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	84.2213
PMC6138639-41467_2018_6247_MOESM5_ESM.xlsx-S2_7_ChIP-seq_RNA-seq_overlaps-49_common_elements_in_ZZZ3_bound_and_shZZZ3_Up_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
Hs-578T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33707
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
K562_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157899
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.530967
TE14_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	4.21752
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19767
PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55884477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71157
BRD-K64147309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8481
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.096
BRD-K42185771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23729
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37619154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23431
BRD-K94277689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23765
A549_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144918
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305734
flumethasone-pivalate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16711
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1189
Nuclear envelope	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.579185
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:M11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01743
BRD-K07665396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20843
GSE206729_3_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.28592
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.74028
BRD-K51215422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12876
BRD-K48188521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43485
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02213
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4774
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.40081
LU65_LUNG	CCLE Cell Line Proteomics	1.0	4.7641
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.98749
Bile duct cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71552
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468546
DA-40-HO94_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241373
A549_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153729
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357576
Organelle envelope	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
BRD-K99446825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27367
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29136
BRD-K70854630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37063
thiamphenicol-glycinate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07982
RNA 3'-end processing	GO Biological Process Annotations 2023	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.40047
BRD-K31852848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35263
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.634819
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8843
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39158
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44107
BRD-K88323568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91621
VB-89-RG34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272066
PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX	Rummagene Transcription Factor Associations 2026	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.540422
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33657
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
BRD-K79232672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07737
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49461735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55888
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47255
BRD-K41202439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92591
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06121
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.769938
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93063
BRD-K15615178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00173
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76998
BRD-A39031631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33384
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.238358
DD-93-NF74_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201318
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32979
8645_TACC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.538618
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385314
BRD-K74626943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15071
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23622
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11666716-41698_2024_782_MOESM1_ESM.pdf-2-PRDM10_PRDM10	Rummagene Transcription Factor Associations 2026	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.890886
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K46936325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41424
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05264
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04519
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149943_1_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20091
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422161
BRD-K47498351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12813
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39971
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32703
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54121
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67373
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6311
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.06061
BRD-K75074041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15099
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07976
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54225
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94427708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05889
A549_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140622
AF-73-HJ84_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272197
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401694
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.991695
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SA-31-VB03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.875691
BRD-K58735963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1111
BRD-A73150064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11195
BRD-K75672292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05507
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56742
BRD-K67142640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02435
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62225
GSE163052,GSE163198_2_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
Histone pre-mRNA 3'end processing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.708
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36513
BRD-K46120925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1531
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62822
EF-73-IP33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242425
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06122
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40991
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.995
BRD-K75857911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0089
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381923
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43798
ITGAV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25047
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261625
BRD-K12833024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10601
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62994
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Protein phosphatase type 2A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01072
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26803
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K78477132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85506
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.423429
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
BF-89-QD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283671
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.576852
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03482
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21241
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02286
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
S0-EE-XMXE_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459999
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03276
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6292
PMC11955568-41467_2025_57429_MOESM9_ESM.xlsx-Data_S7-JUN_OIS_Martinez2020_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16034
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25581
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9911
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13232
Finding Of Mean Corpuscular Hemoglobin	DisGeNET Gene-Phenotype Associations	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02487
HUH6_LIVER	CCLE Cell Line Proteomics	1.0	4.29776
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K42333498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06273
CRCGN016_MCF10A.WT.HP_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15598
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62536891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11657
NELF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.75
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360068
EB-09-OC36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325936
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.612666
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56031
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226345
ELP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40377
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227734
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.4314
BRD-K20171002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37707
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10241968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64249
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K11331752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0136
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61236
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.551913
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.683
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74424
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.370482
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6769
BRD-K50942788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10372
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276746
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35826866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1404
BRD-K81372870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61425
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Anacardic Acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0183097
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.55286
BF-27-HP68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237196
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0198
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373083
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
NE-37-BQ24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231068
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3502
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57645
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81604
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23972
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10565
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20401
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3113
GSE153189_1_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0926
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08304
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80765
LD-14-PB06_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303717
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43311
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K15827385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20786
JIMT1_BREAST	CCLE Cell Line Proteomics	1.0	2.19596
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.5785
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61185
BRD-K77490065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04522
BRD-K99644502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24378
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.36472
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257222
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.53456
BRD-A42246453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07468
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.364132
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13578
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.57322
DCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50639
BRD-K58498516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01065
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.01253
AD-66-NV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.696209
BRD-K55869732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38224
BRD-K76166595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18765
MCF7_PF-573228_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134254
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355292
BRD-K61386375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16555
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
BRD-K22875057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48229
BRD-K54384984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21383
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.868
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334085
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35398
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15172
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3807
BRD-K87433679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04512
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75136523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55228
BRD-K11399565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28256
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33123
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21039
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
BRD-K06166879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11355
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49811
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.787548
BRD-K79402882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14494
PMC7064337-elife-51373-supp2.xlsx-847_genes_down-regulated-List_of_847_genes_down-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15532741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04188
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mean corpuscular hemoglobin	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89845
BRD-K01716842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54853
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332021
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20259776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23901
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563685
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73858940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22337
BRD-K55814495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02472
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431669
BRD-K37770214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1764
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392269
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21617
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82453
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-down_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07734771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47077
regulation of DNA-templated transcription elongation	GO Biological Process Annotations 2025	1.0	null
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06679
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90956468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23954
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12722
BRD-K03733288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68518
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2582
snRNA 3'-end processing	GO Biological Process Annotations 2023	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00687
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K65969715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33305
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265325
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BE-28-WW67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220112
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CAKI1_KIDNEY	CCLE Cell Line Proteomics	1.0	2.74924
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.77415
HC-76-SY22_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20516
GSE187005_5_v_2_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Super elongation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2845
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10691
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PA-25-OV46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233917
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PA-57-FX61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261169
KU1919_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	2.64068
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4306
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367032
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7903
MCF7_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012905
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.44315
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34204
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02866
SW480_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	7.09848
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08307
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03516
BRD-K83456424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08142
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04432
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461992
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40402
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6775
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44617
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9351
CRCGN011_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1557
BRD-K14081852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05959
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468261
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14037093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32038
AD-31-GO06_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.688548
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30946
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02643
BRD-K39710695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05798
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43744
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.5865
BRD-A06840811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02324
GSE221742,GSE221743_1_v_2_sipa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37866276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26892
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76625
3447_GNL3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.917866
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07764
snRNA-activating protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
BRD-K94273044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10669
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07844
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74091626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15642
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.739582
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16353
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221558
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664975
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24407
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22281
RA-49-ZB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.529781
BRD-A43330902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59907
BRD-K55104181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10451
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09311
BRD-K59386816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18255
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236475
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37544
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.72775
BATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91011
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U7 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9799
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08715020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34789
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2279
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.518
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55651
PMC5840266-41598_2018_22384_MOESM13_ESM.xlsx-RNF181_KD_significant-Unnamed_23_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27228
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07777
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63162
A172_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	2.08113
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
troxerutin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37147
BRD-K93283197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06601
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MTREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K11696795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14384
CRCGN017_MCF10A.TP53.M_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06499
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05667
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94199
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.54532
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47858507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55969
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46862
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73458
CRCGN017_MCF10A.WT.HP_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46791
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387504
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67980271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49033
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350177
BRD-K34974135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03798
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22405
BRD-K16525290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54928
BRD-K94088690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34947
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39390441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19369
nucleus	GO Cellular Component Annotations 2025	1.0	null
BRD-K58208155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17899
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.84801
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
ABCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14727
TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.12652
VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K31748787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53323
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-5.48468
BRD-K52361779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10751
BRD-K35635390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02788
MCF7_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118985
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58907
Adductor magnus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
BRD-K83127279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5242
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304443
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.578
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27584
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28629
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215419
f1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.72015
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98942
snRNA metabolic process	GO Biological Process Annotations 2023	1.0	null
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49433
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21282
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22789
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07313
BRD-A64523751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34035
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31077
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09161
Nuclear membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22447639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56805
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4446
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.59329
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62038
9226_TRAF2_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.719469
BRD-K57616143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53187
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00831
BRD-K46119789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65638
BRD-K25846934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37058
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82916
CB-55-AK76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205996
BRD-K61533770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91243
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.700697
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355643
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
carboxy-terminal domain protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
1972_CWC22_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.51416
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87316858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13874
ZM-226600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08711
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21412
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
6152_PDCD11_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.543421
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1844
BRD-K86232678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23443
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
snRNA processing	GO Biological Process Annotations 2023	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65039
C18orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51912
BRD-K25465939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15368
BRD-K69348766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01138
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74257
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276791
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67207
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.920569
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389595
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12175
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A79248021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28787
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63964
11227_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.711169
BRD-K59100858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08528
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11301
CRCGN008_HEPG2_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02405
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37253
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476009
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.55023
BRD-K84090286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00249
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484391
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13782
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53757555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02482
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03224
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.461122
BRD-K88421348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25793
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH4_LIVER	CCLE Cell Line Proteomics	1.0	2.02376
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35532
BRD-K36190163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44818
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32522654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75413
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55447
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04918
BRD-A69110668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85239
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21706
BE-81-QL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04899
BRD-A03898562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02468
BRD-K73587666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04173
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.789696
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432459
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0809
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72662
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5852
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45714931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0382
LIVF001-012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00278
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35574
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8027
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2268
Folic acid deficiency anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.333137
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95114614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24554
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13395
BRD-K84794783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45757
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.533489
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.60694
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.03227
PMC6080909-JEM_20171312_TableS1.xlsx-Fig_1_B_THP1_Pulldown_Targets-Unnamed_1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null