association	dataset	threshold value	standardized value
MCF7_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0282218
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47062
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42573
MCF7_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0087102
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72843
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20207
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50893
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.7477
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8679
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98097
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
GSE236497,GSE236500_1_v_0_pemrametostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72641
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
GSE160817_3_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135514_2_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8382
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92851
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.723
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.23979
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69045
MCF7_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114416
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2542
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44288
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07224
RSBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68709
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64333
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81914
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65798
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33287
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60825
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11801
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79254
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
MCF7_AZD1480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137065
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40374
ABCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73351
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEPTIN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37088
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27514
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29383
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5424
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5074
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87709
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8616
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192156
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23197
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10054
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-28-ENSG00000221818_EBF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27902
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166536_3_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5247
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3334
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63332
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0103515
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.723
GSE145476_1_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0681
MCF7_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162676
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06333
MCF7_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150172
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHST7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87615
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03137
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
MCF7_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161485
MCF7_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141267
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6786
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148734
PMC10713402-aging-15-205220-s005.docx-0-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35561
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Iniparib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013923
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97083
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1633
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5353
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08869
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19836
NEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00863
MCF7_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170404
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8323949-pcbi.1009228.s007.xlsx-HNSCC_ALL_exceptLN-X17_ZNF717	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9244
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15192
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_4_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8406
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60835
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9928
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0319
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44875
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.965
MCF7_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197108
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61667
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2222
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04831
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1634
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13293
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60401
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45458
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149568
HBS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71809
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0548
Esophageal squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1835
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.595
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40841
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37544
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46097
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55571
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119303
MCF7_Patupilone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119932
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94692
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GAS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99003
GSE225735_1_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53441
EFNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38046
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03659
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88644
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.653
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155059
MCF7_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014653
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48327
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39361
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.6864
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44172
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15142
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75291
GSE175920_0_v_3_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49906
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91129
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8152
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50924
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58142
MCF7_RG108_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014781
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76539
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32398
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.965
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.82461
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91977
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1312
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97695
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78109
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86828
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4569
CNKSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13456
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3641
GSE148888_0_v_1_fstl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99898
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0248
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157663
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4949
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40498
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60805
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29637
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3223
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4688
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5594
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23734
MCF7_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138989
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4069
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-NCOA3_mod_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.869
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73161
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46883
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18674
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52381
WIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75718
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35433
ZNF579	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78761
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68371
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47887
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66364
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72306
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9377
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43827
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92743
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29935
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39148
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41204
GSE198054,GSE198057_0_v_1_csf1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3
MCF7_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159482
MCF7_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01352
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07357
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IDH3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42913
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8271
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22436
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8345
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr19_18280332_A_AG_b38	GTEx eQTL 2025	1.0	1.23681
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8323949-pcbi.1009228.s007.xlsx-X17-Unnamed_0_ZNF717	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KCNK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95026
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36692
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71855
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47973
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0834
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27202
Medication use (thyroid preparations)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.40458
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62777
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31791
SW-1353 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4028
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92586
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48534
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5342
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
GSE246576,GSE246826_0_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PHOSPHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13058
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49217
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7417
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Visceral adipose tissue volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
MCF7_CUDC-907_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0103784
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64007
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0496
MCF7_Regorafenib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145799
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55726
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81596
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18406
MCF7_Disulfiram_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115746
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37636
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73196
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66186
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3326
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71397
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94227
spermatid development	GO Biological Process Annotations 2025	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167087
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127916_1_v_3_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.723
MCF7_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133373
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-MLL-AF4_Patient_Cells-Non-spreading_targets_gene_names_302_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173840_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Box H/ACA RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66955
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36875
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02518
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93218
GSE135350_2_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
A body shape index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.03979
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55007
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37591
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2928
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2805
MED23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42893
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Panobinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100522
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86427
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43725
PMC11237048-41598_2024_64364_MOESM1_ESM.pdf-28-EBF2_EBF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6281
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81853
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43428
CACUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36657
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
chr19_18272918_T_C_b38	GTEx eQTL 2025	1.0	2.30924
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01039
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7663
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00839662
A549_JQ1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186838
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.813
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60985
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19186
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45118
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109603
MCF7_Motesanib Diphosphate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139356
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44938
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7458
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7255
PMC9558712-Data_Sheet_2.xlsx-POU3F4_WT_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.475
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151865
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12338
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23102
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39171
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.8057
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_REPRESSED-RING1B_EWSR1-FLI1_repressed_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02362
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Human papillomavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_3h_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138923
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66967
MCF7_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0097371
CITED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57121
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45678
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0458
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9472
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7873
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49908
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160631
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
MCF7_UNC0379_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125415
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42233
GSE189941_1_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
Acrosomal matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79697
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6646
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32212
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34989
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09413
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26037
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3059
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0758
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82024
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2828
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.515
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.0
MCF7_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00848712
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7058
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87384
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06532
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87184
chr19_18291307_G_A_b38	GTEx eQTL 2025	1.0	1.83421
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37078
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21501
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5788
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63853
GSE138939_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14724
MCF7_Resminostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00804874
Mucinous stomach adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6474
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0249
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2812
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56171
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49524
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44571
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40367
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124925
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5868
MCF7_Roscovitine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154771
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59291
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41318
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.046
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
MCF7_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114226
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4882
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
GSE182680,GSE182683_0_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29668
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81683
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0235
MCF7_JNJ-7706621_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0114488
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27878
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0225722
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138403
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1345
PMC11185845-NIHMS1996282-supplement-Table_S1.xls-TableS1_txt-CB_TBL1XR1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Pelitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138285
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31864
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1946
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00805
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_TAK-901_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017984
MCF7_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154199
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
GLB1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94682
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48413
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44956
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52334
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27262
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34396
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39523
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13734
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87998
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35826
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17883
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.91184
MCF7_Patupilone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125852
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0667
GAIT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92427
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
MCF7_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130406
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55914
chr19_18287818_G_C_b38	GTEx eQTL 2025	1.0	1.97642
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06208
C22orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7588
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163428
MCF7_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0243764
CIAO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12754
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5662
A549_JQ1_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119645
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.869
chr19_18283269_G_A_b38	GTEx eQTL 2025	1.0	2.11088
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08271
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21277
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8084
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8832
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7056
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122509,GSE122513_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr19_18293908_A_G_b38	GTEx eQTL 2025	1.0	2.7759
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84921
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.723
PSENEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0363
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84232
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08064
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
MCF7_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150439
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31399
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TEX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41595
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43195
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30528
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31997
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48524
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70512
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8748
MCF7_Andarine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144521
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
PMC5313641-CAM4-6-349-s001.docx-0-HIVEP1_HIVEP1	Rummagene Transcription Factor Associations 2026	1.0	null
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62829
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65961
MCF7_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185365
MCF7_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00972844
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33393
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_BMS-265246_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175323
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10483
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4411
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4339
chr19_18282084_C_T_b38	GTEx eQTL 2025	1.0	1.44025
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37888
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10056
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98114
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94216
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263152
MCF7_Abexinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0092165
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47641
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82032
chr19_18277130_A_G_b38	GTEx eQTL 2025	1.0	4.01996
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56883
SEC14L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69977
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98293
MCF7_Sorafenib Tosylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00947662
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0275
MCF7_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016065
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09265
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15237
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48084
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39549
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78086
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00966595
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86735
MCF7_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0247219
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6074
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3797
MCF7_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170895
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46693
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88771
MCF7_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124986
MCF7_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138984
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36102
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
TUBA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4928
MCF7_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015872
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0006
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7641
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0648
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO3-_-_vs_FOXO3_hMyotubes_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54086
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21357
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17046
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0574
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44912
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115113
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
PMC7585942-mmc5.xlsx-RBM10_OE_upregulated-Supplementary_Table_S5_RBM10-mediated_gene_expression_changes_in_BEAS-2B_and_PC9_cells_Cutoff_P_0_05_log2FoldChange_1_KD_knockdown_OE_overexpression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5236
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRPRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51216
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174104
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31809
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53773
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.826
APBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8176
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Aminoglutethimide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144021
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88045
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50148
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
AMMECR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60612
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64987
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00699
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70871
PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55038
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.843
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.23979
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7075
AP5S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15062
GSE197197,GSE212981_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-A549_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_A549_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5468
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95486
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6841
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35763
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03325
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02939
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2047
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
GSE223008_5_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26267
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.53697
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43476
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18641
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.653
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8495
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0098465
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76046
MCF7_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0222105
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.861
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lsd1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.6181
EEF1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2911
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06969
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54429
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22465
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
GSE85995_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_6_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40668
GSE95771_0_v_2_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17696
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54547
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80637
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04452
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-382-CSRNP1_CSRNP1	Rummagene Transcription Factor Associations 2026	1.0	null
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33086
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58718
MCF7_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145419
PMC11846991-41598_2025_90195_MOESM1_ESM.pdf-11-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173201_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00594
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1805
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36448
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66951
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92453
Mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
MCF7_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136163
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26126
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11573
MCF7_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176679
GSE121009,GSE121014_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7685
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19863
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8476
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75862
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85154
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69648
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2884
GSE227592_0_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Fedratinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159363
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89934
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32694
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22295
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
chr19_18282103_A_G_b38	GTEx eQTL 2025	1.0	1.05578
SH3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50494
GSE223008_5_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45207
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7304
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24693
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58551
MCF7_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160823
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
RHEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06381
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96584
MCF7_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.031052
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.373
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22462
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30154
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19992
ZNF329	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
MCF7_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171262
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08783
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7185
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Bisindolylmaleimide IX_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123185
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56769
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
Gastroesophageal reflux disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.391
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2402
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56376
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE160817_2_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115657
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7305
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComUp-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4628
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NOVA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99918
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65407
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74787
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03781
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91339
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56599
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LENG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37492
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPP2R5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90196
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77059
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.723
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5472
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66907
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17212
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96072
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
MCF7_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173811
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.942
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46276
MCF7_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165541
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.566
GSE154577_2_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254526,GSE254528_0_v_1_phf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9076
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73552
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88141
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30746
GSE99687_0_v_1_smad5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0261
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52393
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77914
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79293
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17699
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.965
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62144
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27184
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6799
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186131
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25803
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30376
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38881
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58912
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56565
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7831
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48277
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3187
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4609
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03205
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr19_18285487_A_G_b38	GTEx eQTL 2025	1.0	1.4346
chr19_18291240_C_T_b38	GTEx eQTL 2025	1.0	1.00458
MCF7_Entacapone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130699
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93588
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9343
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1762
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2762
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Classical_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54049
KRT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23316
GSE180951_6_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
GSE182640_1_v_0_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11025
GSE185519_1_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46243
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20109
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4909
MCF7_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124692
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86874
MCF7_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142889
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84243
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86847
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13968
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70002
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56417
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPACA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77549
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_TG101209_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136421
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3238
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6102
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44702
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2544
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38803
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.869
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
Borst-Jadassohn intraepidermal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
LYPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63665
H4C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57907
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Box C/D RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
GSE158834_1_v_5_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268027
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC25A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03983
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63136
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3483
MCF7_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137212
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66846
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85994
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.0626
MCF7_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016093
MCF7_Hesperadin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113726
PMC7064337-elife-51373-supp2.xlsx-652_genes_up-regulated-List_of_652_genes_up-regulated_after_PHF19_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DDX39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5781
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TXNDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9638
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40646
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110954
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20484
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54344
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24812
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72762
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42886
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.869
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57208
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8408
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180951_6_v_5_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
MCF7_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195578
MCF7_Alisertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117114
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66327
MCF7_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119847
MCF7_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134937
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52091
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41047
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.311
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53463
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193604
chr19_18291332_C_G_b38	GTEx eQTL 2025	1.0	2.62934
PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26617
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
MCF7_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016733
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4583
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73998
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07247
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11643
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6446
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Rucaparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137557
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.965
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92319
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14328
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1922
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72138
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83329
MCF7_A-366_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139663
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93789
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0597
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2778
MCF7_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126188
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155249
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37152
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.628
MCF7_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00794218
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4809
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76273
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10133
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44896
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3995
PMC10305740-pwac061_suppl_supplementary_table_s1.xlsx-FOXO3-knockout_bulk_RNA-seq-Unnamed_1_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206242
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3823
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
MAST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37231
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51833
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89598
MCF7_Prednisone_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145721
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4549
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14004
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGF1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53277
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46001
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2718
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50319
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
MCF7_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108363
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33444
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9205
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0824
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40982
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Givinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104225
Autoimmune thyroiditis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.965
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41457
chr19_18284966_T_C_b38	GTEx eQTL 2025	1.0	1.51249
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45742
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5523
MCF7_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020927
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6404
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4292
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43056
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2426
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39426
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33806
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52616
PMC8986528-41586_2022_4598_MOESM11_ESM.xlsx-Extended_Data_Fig_6m-NOL9_KD_downreg_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18038
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07968
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TOR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97292
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30426
SYCE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16282
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20576
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2624
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3853
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07028
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155222
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165985
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11063202-41420_2024_1940_MOESM2_ESM.xlsx-THP1-EP300_KOvsNontarget-gene_id_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09631
GSE95771_0_v_1_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8785
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54648
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36884
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74292
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17819
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93395
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM83H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59214
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25181
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85766
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99194
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18063
SUIT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GSE182680,GSE182683_10_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5556
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32506
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57349
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.734
BCL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15988
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45218
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6741
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
HERPUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30907
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAMTOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51372
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50127
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8164
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.5453
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.96
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82821
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94687