association dataset threshold value standardized value intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.177439 PPARD_KO_GDS4320_619_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PMC6618143__F3 PFOCR Pathway Figure Associations 2023 1.0 null negative regulation of cell communication GO Biological Process Annotations 2015 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41395 GATA1-19941827-MEL-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null defense GeneRIF Biological Term Annotations 1.0 null Perturb_7980_KD_Kmt2d_SRP253323 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.06574 production GeneRIF Biological Term Annotations 1.0 null MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.33972 molecular_function GO Molecular Function Annotations 2015 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null organic substance metabolic process GO Biological Process Annotations 2015 1.0 null SW620 DepMap CRISPR Gene Dependency 1.0 3.53749 zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092771 NCIH1869 DepMap CRISPR Gene Dependency 1.0 3.05215 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NCIH1993 DepMap CRISPR Gene Dependency 1.0 8.90396 RAJI DepMap CRISPR Gene Dependency 1.0 5.88032 intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049726 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 negative regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null response to hormone GO Biological Process Annotations 2015 1.0 null SNU283 CCLE Cell Line Gene Expression Profiles 1.0 1.53117 cellular response to organic substance GO Biological Process Annotations 2015 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ETS1 ENCODE Transcription Factor Targets 1.0 null COLO205 CCLE Cell Line Gene CNV Profiles 1.0 1.96352 SIMA CCLE Cell Line Gene Expression Profiles -1.0 -1.47359 regulation of response to biotic stimulus GO Biological Process Annotations 2015 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.40925 OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null liver HPA Tissue Protein Expression Profiles -1.0 -1.22104 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144846 GA10 CCLE Cell Line Gene Expression Profiles 1.0 2.08633 Perturb_15672_KD_Hnrnpc_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.5481 negative regulation of toll-like receptor 4 signaling pathway GO Biological Process Annotations 2023 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886249 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055586 MEIS1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14377 cellular response to lipid GO Biological Process Annotations 2023 1.0 null mediated GeneRIF Biological Term Annotations 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null negative regulation of type i interferon production GO Biological Process Annotations 2015 1.0 null NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -1.55004 cellular catabolic process GO Biological Process Annotations 2015 1.0 null response to interferon-beta GO Biological Process Annotations 2015 1.0 null nutrition disease GWASdb SNP-Disease Associations 1.0 0.386378 organic acid metabolic process GO Biological Process Annotations 2015 1.0 null response to lipopolysaccharide GO Biological Process Annotations 2023 1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null BV-173 COSMIC Cell Line Gene Mutation Profiles 1.0 null immune GeneRIF Biological Term Annotations 1.0 null regulation of antimicrobial humoral response GO Biological Process Annotations 2015 1.0 null tolerance GeneRIF Biological Term Annotations 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831645 Glioma DisGeNET Gene-Disease Associations 1.0 null pancreas HPA Tissue Protein Expression Profiles -1.0 -0.795216 short-chain fatty acid catabolic process GO Biological Process Annotations 2015 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.59647 negative regulation of toll-like receptor 2 signaling pathway GO Biological Process Annotations 2023 1.0 null TN2 DepMap CRISPR Gene Dependency 1.0 2.92876 Perturb_1532_KO_Hsp90b1_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.64549 cellular_component GO Cellular Component Annotations 2015 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058903 promotes GeneRIF Biological Term Annotations 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null monocarboxylic acid catabolic process GO Biological Process Annotations 2015 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835239 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886249 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056514 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31039 KMH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null human immunodeficiency virus infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.14124 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28225 HCC33 CCLE Cell Line Gene CNV Profiles 1.0 1.93777 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.7574 L428 CCLE Cell Line Gene CNV Profiles -1.0 -1.40797 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26027 KYSE520 DepMap CRISPR Gene Dependency 1.0 4.80921 cecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.558856 LB647-SCLC COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908357 primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04935 Lung Diseases CTD Gene-Disease Associations 1.0 1.49967 positive regulation of reactive oxygen species metabolic process GO Biological Process Annotations 2015 1.0 null mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.171409 HCC2218 CCLE Cell Line Gene Expression Profiles 1.0 3.05885 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.88371 A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.32879 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular lipid metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_5725_KO_Mertk_SRP279562 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.5742 response to chemical GO Biological Process Annotations 2015 1.0 null DBTRG05MG CCLE Cell Line Gene Expression Profiles -1.0 -2.10508 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055518 peripheral blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.10012 TC-YIK COSMIC Cell Line Gene Mutation Profiles 1.0 null TAL1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949045 U-698-M COSMIC Cell Line Gene Mutation Profiles 1.0 null small molecule metabolic process GO Biological Process Annotations 2015 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.833358 bone marrow-derived dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.471927 Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -2.8826 positive regulation of antimicrobial humoral response GO Biological Process Annotations 2023 1.0 null regulating GeneRIF Biological Term Annotations 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052995 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051569 Perturb_3220_KO_C3ar1_ERP024585 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.53404 NCIH446 CCLE Cell Line Gene Expression Profiles -1.0 -1.89603 MDAMB134VI CCLE Cell Line Gene CNV Profiles -1.0 -1.33519 CL-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12481 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null indicated GeneRIF Biological Term Annotations 1.0 null colon GTEx Tissue Gene Expression Profiles 1.0 1.16753 CA9-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null MOLT-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of multi-organism process GO Biological Process Annotations 2015 1.0 null Perturb_2050_KO_Bmal1_SRP124290 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.70213 connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04475 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.170888 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.11037 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.07914 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null LU65 CCLE Cell Line Gene Expression Profiles 1.0 1.85179 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23693 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 PCI15A DepMap CRISPR Gene Dependency 1.0 2.93703 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044418 Edema CTD Gene-Disease Associations 1.0 1.07199 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32352 regulation of metabolic process GO Biological Process Annotations 2015 1.0 null DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 2-methylcitrate dehydratase activity GO Molecular Function Annotations 2015 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02372 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MIST1_KO_GDS1731_758_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null cellular response to biotic stimulus GO Biological Process Annotations 2015 1.0 null lung HPA Tissue Protein Expression Profiles -1.0 -0.795216 CMK CCLE Cell Line Gene CNV Profiles 1.0 1.49225 COLO800 CCLE Cell Line Gene Expression Profiles -1.0 -2.32231 mitochondrion COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829091 Perturb_1501_KO_Tirap_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.41392 Perturb_1804_KO_lncFAO_SRP192861 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 response to cytokine GO Biological Process Annotations 2015 1.0 null response to interleukin-1 GO Biological Process Annotations 2015 1.0 null CMK115 CCLE Cell Line Gene CNV Profiles 1.0 1.74882 cellular response to interferon-gamma GO Biological Process Annotations 2015 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220152 HNF4alpha_KO_GDS1915_173_mouse_Small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_1473_KO_Hsp90b1_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.06367 nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73291 molecular GeneRIF Biological Term Annotations 1.0 null SCD_KO_GSE24243_46_mouse_Skin (8-9 wk) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cellular response to lipopolysaccharide GO Biological Process Annotations 2015 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950465 acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050083 NCIH510 CCLE Cell Line Gene CNV Profiles -1.0 -1.97627 NCIH522 CCLE Cell Line Gene CNV Profiles -1.0 -1.52135 regulation of immune system process GO Biological Process Annotations 2015 1.0 null RL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.918848 FLI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SMARCA4 ChEA Transcription Factor Targets 1.0 null Skin Diseases CTD Gene-Disease Associations 1.0 1.142 negative regulation of nf-kappab transcription factor activity GO Biological Process Annotations 2015 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TE617T CCLE Cell Line Gene Expression Profiles 1.0 1.47573 Perturb_14803_KD_Gm26917_SRP340980 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 TAL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056043 mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 single-organism process GO Biological Process Annotations 2015 1.0 null NH12 DepMap CRISPR Gene Dependency 1.0 4.90235 PANC1 CCLE Cell Line Gene Expression Profiles 1.0 1.57145 HPAFII CCLE Cell Line Gene CNV Profiles -1.0 -2.05841 positive regulation of immune system process GO Biological Process Annotations 2015 1.0 null GATA1_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null small molecule catabolic process GO Biological Process Annotations 2015 1.0 null negative regulation of inflammatory response GO Biological Process Annotations 2023 1.0 null RI1 CCLE Cell Line Gene CNV Profiles 1.0 2.16421 A-VN-1203-2004(H5N1)_Day7-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.9312 disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041767 KASUMI6 CCLE Cell Line Gene CNV Profiles 1.0 1.43466 regulation of type i interferon production GO Biological Process Annotations 2015 1.0 null SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43834 bipolar disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 Perturb_1724_KO_Tet2_SRP353433 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 NOMO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of toll-like receptor 4 signaling pathway GO Biological Process Annotations 2015 1.0 null HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.833358 GATA-1_KD_GDS1245_81_mouse_megakaryocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062564 glucose intolerance DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.378514 organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057996 PMC5796629__F2 PFOCR Pathway Figure Associations 2023 1.0 null macrophage cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.481259 intracellular part GO Cellular Component Annotations 2015 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056972 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056618 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12885 cellular process GO Biological Process Annotations 2015 1.0 null embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.102923 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.16935 cellular response to lipid GO Biological Process Annotations 2015 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053882 Perturb_1821_KO_Irf5_SRP233379 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.34142 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.861259 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null CP66-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_9377_KO_lincRNAEPS_SRP354151 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 HCT-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1978 tolerance induction GO Biological Process Annotations 2015 1.0 null skin cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063282 OUMS23 CCLE Cell Line Gene Expression Profiles -1.0 -1.52858 19605494-TableS3 GeneSigDB Published Gene Signatures 1.0 null NCIH889 CCLE Cell Line Gene CNV Profiles -1.0 -1.83276 negative regulation of toll-like receptor signaling pathway GO Biological Process Annotations 2015 1.0 null SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.308494 15845616-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null GATA1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null gout DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.655254 RCM1 DepMap CRISPR Gene Dependency 1.0 9.04425 SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039617 negative regulation of molecular function GO Biological Process Annotations 2015 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046576 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65909 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1561_KO_Tlr4_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.35635 Perturb_1553_KO_Sf3b6_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.97748 regulation of rna metabolic process GO Biological Process Annotations 2015 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886645 Perturb_1488_KO_Rela_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.70507 JHH7 CCLE Cell Line Gene Expression Profiles 1.0 1.71411 SK-MEL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_SFPI1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ISHIKAWAHERAKLIO02ER DepMap CRISPR Gene Dependency 1.0 3.40305 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null DOV13 CCLE Cell Line Gene CNV Profiles 1.0 1.75109 epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059901 negative regulation of innate immune response GO Biological Process Annotations 2015 1.0 null endotoxin GeneRIF Biological Term Annotations 1.0 null Perturb_1500_KO_Ticam2_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.31059 Perturb_1806_KO_Trif_SRP377807 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.36617 positive regulation of response to biotic stimulus GO Biological Process Annotations 2023 1.0 null lpsstimulated GeneRIF Biological Term Annotations 1.0 null defense response GO Biological Process Annotations 2015 1.0 null SNU449 CCLE Cell Line Gene CNV Profiles -1.0 -1.43817 cellular response to steroid hormone stimulus GO Biological Process Annotations 2015 1.0 null 16717027-Table2 GeneSigDB Published Gene Signatures 1.0 null Perturb_16365_KO_Auf1_SRP076844 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.98192 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39705 cellular response to chemical stimulus GO Biological Process Annotations 2015 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0952 EW-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular response to steroid hormone stimulus GO Biological Process Annotations 2023 1.0 null Perturb_17379_KD_Pparg_SRP190223 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.34297 NCI-H508 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057321 Perturb_1502_KO_Tlr4_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.4423 inflammatory response GO Biological Process Annotations 2015 1.0 null hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.317315 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fatty acid catabolic process GO Biological Process Annotations 2015 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.516891 uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.415814 VCAP COSMIC Cell Line Gene Mutation Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054076 CPC-N COSMIC Cell Line Gene Mutation Profiles 1.0 null vagina GTEx Tissue Gene Expression Profiles -1.0 -1.06998 cellular response to molecule of bacterial origin GO Biological Process Annotations 2015 1.0 null negative regulation of cellular process GO Biological Process Annotations 2015 1.0 null RERFLCAD1 CCLE Cell Line Gene Expression Profiles -1.0 -1.61878 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.49383 regulation of rna biosynthetic process GO Biological Process Annotations 2015 1.0 null negative regulation of signaling GO Biological Process Annotations 2015 1.0 null regulation of biological process GO Biological Process Annotations 2015 1.0 null negative regulation of toll-like receptor 4 signaling pathway GO Biological Process Annotations 2015 1.0 null carboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_11984_KD_Act1_SRP336727 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.260945 HS695T CCLE Cell Line Gene Expression Profiles -1.0 -1.54306 MLMA COSMIC Cell Line Gene Mutation Profiles 1.0 null Fog2_KO_GDS3659_152_mouse_adult heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EPLC272H CCLE Cell Line Gene Expression Profiles 1.0 1.75929 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HUH28 CCLE Cell Line Gene Expression Profiles -1.0 -1.67087 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 JURKAT DepMap CRISPR Gene Dependency 1.0 5.30782 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53087 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05664 negative regulation of NF-kappaB transcription factor activity GO Biological Process Annotations 2023 1.0 null ros GeneRIF Biological Term Annotations 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03608 Perturb_13493_KD_Ncor1_ERP132013 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 UACC812 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 MFE280 CCLE Cell Line Gene Expression Profiles -1.0 -1.98858 positive regulation of defense response GO Biological Process Annotations 2023 1.0 null RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.32264 Septicemia DisGeNET Gene-Disease Associations 1.0 null positive regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null SKMEL30 DepMap CRISPR Gene Dependency 1.0 7.13288 catalyzing GeneRIF Biological Term Annotations 1.0 null 12446012-Table2 GeneSigDB Published Gene Signatures 1.0 null irg1 GeneRIF Biological Term Annotations 1.0 null HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848117 viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044089 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null response to interleukin-1 GO Biological Process Annotations 2023 1.0 null KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.974424 TAL1_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12227 Perturb_11739_KO_Nrf2_SRP108108 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.79687 membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 macrophages GeneRIF Biological Term Annotations 1.0 null Perturb_926_OE_Scnn1b_SRP272854 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.08681 OV90 CCLE Cell Line Gene Expression Profiles 1.0 1.54715 Perturb_167_KO_Itgb3_SRP305656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.50151 negative regulation of inflammatory response GO Biological Process Annotations 2015 1.0 null negative regulation of toll-like receptor 2 signaling pathway GO Biological Process Annotations 2015 1.0 null SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41395 regulation of macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65909 CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null negative regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null air pouch TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.666402 blastocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.483986 cellular response to molecule of bacterial origin GO Biological Process Annotations 2023 1.0 null Prenatal Injuries CTD Gene-Disease Associations 1.0 1.09119 positive regulation of immune response GO Biological Process Annotations 2015 1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.48087 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08687 Perturb_13295_KD_Klf5_SRP307776 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.76846 regulation of cellular macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07649 Cystic Fibrosis_Lung_GSE3100 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.40274 negative regulation of response to biotic stimulus GO Biological Process Annotations 2015 1.0 null cellular response to interleukin-1 GO Biological Process Annotations 2023 1.0 null intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 Hyperplasia CTD Gene-Disease Associations 1.0 1.66382 lipid catabolic process GO Biological Process Annotations 2015 1.0 null RAJI CCLE Cell Line Gene Expression Profiles 1.0 1.91341 JUN_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ChEA Transcription Factor Targets 1.0 null NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12227 intracellular organelle GO Cellular Component Annotations 2015 1.0 null HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890078 MONOMAC6 CCLE Cell Line Gene CNV Profiles 1.0 1.52829 GATA1_G1E-ER4_mm9_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null increasing GeneRIF Biological Term Annotations 1.0 null CMAH_KO_GDS4200_114_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858237 E2A MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_3217_KO_Stat1_SRP271755 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.56725 HDQP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.47761 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829091 response to stimulus GO Biological Process Annotations 2015 1.0 null negative regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2015 1.0 null hippocampus HPA Tissue Protein Expression Profiles -1.0 -2.34145 Perturb_13302_KO_Tet2_SRP338315 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.2518 15947096-TableS1b GeneSigDB Published Gene Signatures 1.0 null monocarboxylic acid metabolic process GO Biological Process Annotations 2015 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0636 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054103 cellular response to lipopolysaccharide GO Biological Process Annotations 2023 1.0 null hypoinflammation GeneRIF Biological Term Annotations 1.0 null positive regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.861259 regulation of cell communication GO Biological Process Annotations 2015 1.0 null Waist Circumference dbGAP Gene-Trait Associations 1.0 0.146448 macrophage BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Perturb_14806_KO_Pdk2/Pdk4_SRP136941 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.19104 A-Vietnam-1203-2004(H5N1)_2day-wtC57BL-6J_None_GSE40792 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.52054 encodes GeneRIF Biological Term Annotations 1.0 null cellular response to progesterone stimulus GO Biological Process Annotations 2015 1.0 null GATA1_G1E-ER4_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null carbon-oxygen lyase activity GO Molecular Function Annotations 2015 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063134 carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.092833 GATA2_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 regulation of humoral immune response GO Biological Process Annotations 2015 1.0 null response to interferon-gamma GO Biological Process Annotations 2015 1.0 null A-CA-04-2009(H1N1)MA_Day1_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.97453 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48391 ZC3H11A ENCODE Transcription Factor Targets 1.0 null carbon-carbon lyase activity GO Molecular Function Annotations 2015 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05599 germ tube COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.02629 Perturb_1725_KO_Tet2_SRP353433 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 HH CCLE Cell Line Gene Expression Profiles 1.0 1.60923 organic substance catabolic process GO Biological Process Annotations 2015 1.0 null TAL1_megakaryocyte_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null tolerance induction to lipopolysaccharide GO Biological Process Annotations 2015 1.0 null negative regulation of response to biotic stimulus GO Biological Process Annotations 2023 1.0 null response to interferon-beta GO Biological Process Annotations 2023 1.0 null TBK1_druginhibition_188_GSE53658 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.9294 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79641 NCIH508 CCLE Cell Line Gene CNV Profiles 1.0 2.09474 Perturb_15678_KD_Srsf6_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SQ1 CCLE Cell Line Gene CNV Profiles -1.0 -2.49351 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_797_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 19.699 protein homodimerization activity GO Molecular Function Annotations 2023 1.0 null mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.152929 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null H357 DepMap CRISPR Gene Dependency 1.0 3.66433 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.3786 RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BICR78 DepMap CRISPR Gene Dependency 1.0 4.41379 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -1.68256 PMC7472464__F7 PFOCR Pathway Figure Associations 2023 1.0 null Perturb_11979_KD_Etv5_SRP304972 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14369 OLIG2 ChEA Transcription Factor Targets 1.0 null regulation of macromolecule biosynthetic process GO Biological Process Annotations 2015 1.0 null KMS21BM CCLE Cell Line Gene Expression Profiles 1.0 2.50595 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ME-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HS172T CCLE Cell Line Gene Expression Profiles -1.0 -1.47181 metabolism GeneRIF Biological Term Annotations 1.0 null positive regulation of humoral immune response GO Biological Process Annotations 2015 1.0 null regulation of transcription, dna-templated GO Biological Process Annotations 2015 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08285 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.889668 cell part LOCATE Predicted Protein Localization Annotations 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932772 RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04825 IALM CCLE Cell Line Gene CNV Profiles -1.0 -1.37161 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01465 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null negative regulation of immune system process GO Biological Process Annotations 2023 1.0 null epithelial ovarian cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.706402 stomach GTEx Tissue Gene Expression Profiles 1.0 0.938981 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.22104 Perturb_794_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080245 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059906 NCIH446 CCLE Cell Line Gene CNV Profiles -1.0 -1.8422 Fetal Death CTD Gene-Disease Associations 1.0 1.40288 Perturb_13490_KD_Ncor1_ERP132013 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.2167 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26027 ileocecum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.324605 MAX ENCODE Transcription Factor Targets 1.0 null Perturb_1560_KO_Tirap_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.15132 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 parenchyma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195672 regulation of toll-like receptor 2 signaling pathway GO Biological Process Annotations 2023 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null negative regulation of DNA-binding transcription factor activity GO Biological Process Annotations 2023 1.0 null cellular response to oxygen-containing compound GO Biological Process Annotations 2023 1.0 null Perturb_1672_KO_Mda5_SRP119759 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.50503 negative regulation of immune response GO Biological Process Annotations 2023 1.0 null E2F1_KD_GDS4094_446_mouse_Mammary tumors GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null regulation of toll-like receptor 4 signaling pathway GO Biological Process Annotations 2023 1.0 null positive regulation of humoral immune response GO Biological Process Annotations 2023 1.0 null PATU8902 DepMap CRISPR Gene Dependency 1.0 4.77908 GATA2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null indicating GeneRIF Biological Term Annotations 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56404 negative regulation of innate immune response GO Biological Process Annotations 2023 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.861259 cellular response to stimulus GO Biological Process Annotations 2015 1.0 null cellular response to tumor necrosis factor GO Biological Process Annotations 2023 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.171149 Lung Injury CTD Gene-Disease Associations 1.0 1.10942 positive regulation of cellular metabolic process GO Biological Process Annotations 2023 1.0 null SLR21 CCLE Cell Line Gene Expression Profiles -1.0 -1.56753 TYKNU DepMap CRISPR Gene Dependency 1.0 3.24073 response to stress GO Biological Process Annotations 2015 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028668 abnormality of body weight GWASdb SNP-Phenotype Associations 1.0 0.340787 response to type II interferon GO Biological Process Annotations 2023 1.0 null autolysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.821288 ovary cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.244232 Perturb_8401_OE_Chrna4_SRP214624 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Hypertension CTD Gene-Disease Associations 1.0 1.02114 16585964-SuppTable6 GeneSigDB Published Gene Signatures 1.0 null increased body weight GWASdb SNP-Phenotype Associations 1.0 0.679979 adult GeneRIF Biological Term Annotations 1.0 null obesity GWASdb SNP-Phenotype Associations 1.0 0.679979 IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19368 Perturb_1600_KO_Ticam1_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.49249 tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.671285 LYL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null OUMS23 CCLE Cell Line Gene CNV Profiles 1.0 1.4324 middle ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.507064 CAOV4 DepMap CRISPR Gene Dependency 1.0 9.54465 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08277 HLE CCLE Cell Line Gene CNV Profiles -1.0 -1.48587 negative regulation of multi-organism process GO Biological Process Annotations 2015 1.0 null NCIH1963 CCLE Cell Line Gene CNV Profiles 1.0 1.61852 CL-40 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.980637 cellular response to cytokine stimulus GO Biological Process Annotations 2015 1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11924 defense response to virus GO Biological Process Annotations 2023 1.0 null Perturb_2157_KO_Tnfaip3_SRP126279 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.577 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.10014 HDQP1 CCLE Cell Line Gene CNV Profiles 1.0 1.5959 HUH28 CCLE Cell Line Gene CNV Profiles 1.0 1.51967 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null Perturb_1453_KO_Ash2l_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.58569 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -1.22104 Perturb_1494_KO_Sf3b6_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.07723 regulation of cellular process GO Biological Process Annotations 2015 1.0 null response to endogenous stimulus GO Biological Process Annotations 2015 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829091 GR MotifMap Predicted Transcription Factor Targets 1.0 null ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.067133 inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.139046 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 lyase activity GO Molecular Function Annotations 2015 1.0 null MECOM-23826213-KASUMI-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null SCC9 DepMap CRISPR Gene Dependency 1.0 5.16892 regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14296 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12227 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.38071 Infertility, Female CTD Gene-Disease Associations 1.0 1.01625 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.918848 Perturb_9304_KO_Gsk3b_SRP295417 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cellular response to tumor necrosis factor GO Biological Process Annotations 2015 1.0 null IM95 CCLE Cell Line Gene CNV Profiles -1.0 -1.41875 response to molecule of bacterial origin GO Biological Process Annotations 2023 1.0 null OE19 CCLE Cell Line Gene Expression Profiles 1.0 1.39556 autophagic vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.429465 SETDB1 ChEA Transcription Factor Targets 1.0 null ECC12 CCLE Cell Line Gene CNV Profiles -1.0 -1.34021 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null response to external biotic stimulus GO Biological Process Annotations 2015 1.0 null RL DepMap CRISPR Gene Dependency 1.0 3.49621 HMC18 CCLE Cell Line Gene Expression Profiles 1.0 2.50581 bone inflammation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063784 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69582 regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Ebolavirus(ZEBOV)_3day_Spleen_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.28742 MAFK ENCODE Transcription Factor Targets 1.0 null ZC3H11A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of lipopolysaccharide-mediated signaling pathway GO Biological Process Annotations 2015 1.0 null negative regulation of cytokine production GO Biological Process Annotations 2015 1.0 null HS255T CCLE Cell Line Gene Expression Profiles -1.0 -1.68945 Perturb_15680_KD_Srsf9_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.8 hyperglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.145327 A-VN-1203-2004(H5N1)_Day7-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.91595 MmgE/PrpD InterPro Predicted Protein Domain Annotations 1.0 null Perturb_11978_OE_Ifng_ERP109050 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.66068 KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.980637 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.10222 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858237 single-organism catabolic process GO Biological Process Annotations 2015 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.05337 Infection by Yersinia enterocolitica_macrophage_GSE2973 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.00681 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028692 KP-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null propionate metabolic process GO Biological Process Annotations 2015 1.0 null HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32731 vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.12687 negative regulation of signal transduction GO Biological Process Annotations 2015 1.0 null response to organic cyclic compound GO Biological Process Annotations 2015 1.0 null positive regulation of cellular process GO Biological Process Annotations 2015 1.0 null intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 response to organic substance GO Biological Process Annotations 2015 1.0 null acquired immunodeficiency syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161139 regulation of gene expression GO Biological Process Annotations 2015 1.0 null SW1463 CCLE Cell Line Gene CNV Profiles 1.0 1.40794 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null melanoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064559 Necrosis CTD Gene-Disease Associations 1.0 1.34547 NB10 DepMap CRISPR Gene Dependency 1.0 2.52307 parenchymal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33744 HEL9217 DepMap CRISPR Gene Dependency 1.0 2.87587 catalytic activity GO Molecular Function Annotations 2015 1.0 null PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 18270326-Table1 GeneSigDB Published Gene Signatures 1.0 null links GeneRIF Biological Term Annotations 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 Sendai virus infection_Tracheal epithelium_GSE10211 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.5603 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956701 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null waist circumference GAD Gene-Disease Associations 1.0 null Scd1_DELETION_GDS4910_309_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null positive regulation of antimicrobial humoral response GO Biological Process Annotations 2015 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.024693 MYC_Activation - 2 hours_GDS2025_723_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null tca GeneRIF Biological Term Annotations 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886249 GATA2 ENCODE Transcription Factor Targets 1.0 null carboxylic acid catabolic process GO Biological Process Annotations 2015 1.0 null SK-MEL-28 COSMIC Cell Line Gene Mutation Profiles 1.0 null blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.134595 response to oxygen-containing compound GO Biological Process Annotations 2015 1.0 null T3M4 DepMap CRISPR Gene Dependency 1.0 3.28335 TGF-beta_OE_GDS2974_137_mouse_corneas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GCT CCLE Cell Line Gene Expression Profiles 1.0 2.09068 positive regulation of biological process GO Biological Process Annotations 2015 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.344556 Sepsis DisGeNET Gene-Disease Associations 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34334 cellular response to cytokine stimulus GO Biological Process Annotations 2023 1.0 null H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null A-Vietnam-1203-2004(H5N1)_2day-IDO1KO_None_GSE40792 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.15861 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041432 granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224893 blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.274744 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858237 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042907 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DUSP1_KO_GDS1606_773_mouse_spleens GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SAT DepMap CRISPR Gene Dependency 1.0 2.04777 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04426 other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.080619 A-CA-04-2009(H1N1)_Day3_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.29055 response to biotic stimulus GO Biological Process Annotations 2015 1.0 null secondary lysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.589714 fetal GeneRIF Biological Term Annotations 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7335 EP300_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null F36P CCLE Cell Line Gene CNV Profiles -1.0 -1.38451 Perturb_1559_KO_Ticam2_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.55078 Perturb_14023_KO_Ppid_DRP008865 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.32017 Perturb_1524_KO_Dhx15_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.34967 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of cytokine production GO Biological Process Annotations 2015 1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03608 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043291 regulation of toll-like receptor signaling pathway GO Biological Process Annotations 2015 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.33346 negative regulation of defense response GO Biological Process Annotations 2015 1.0 null regulation of response to stress GO Biological Process Annotations 2015 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.211023 Disease Models, Animal CTD Gene-Disease Associations 1.0 1.21823 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066639 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 embryo implantation GO Biological Process Annotations 2015 1.0 null Perturb_11102_KO_Tpt1_SRP214000 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 single-organism cellular process GO Biological Process Annotations 2015 1.0 null cellular response to interferon-beta GO Biological Process Annotations 2023 1.0 null Perturb_18379_KO_Izumo1r_SRP354764 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.60264 regulation of nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null oxoacid metabolic process GO Biological Process Annotations 2015 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MERO48A DepMap CRISPR Gene Dependency 1.0 4.36858 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BJHTERT CCLE Cell Line Gene Expression Profiles -1.0 -2.04053 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08277 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.2201 Perturb_10733_OE_Sirt6_SRP282071 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.3979 regulation of response to stimulus GO Biological Process Annotations 2015 1.0 null MYC_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Whipple's Disease_macrophage_GSE16180 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.77525 Endotoxemia DisGeNET Gene-Phenotype Associations 1.0 null RUNX1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KARPAS422 DepMap CRISPR Gene Dependency 1.0 2.94165 Perturb_15967_KO_Tbet_SRP063567 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.20237 immune system process GO Biological Process Annotations 2015 1.0 null response to ketone GO Biological Process Annotations 2015 1.0 null regulation of innate immune response GO Biological Process Annotations 2015 1.0 null negative regulation of immune system process GO Biological Process Annotations 2015 1.0 null VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null organelle GO Cellular Component Annotations 2015 1.0 null regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null CAL120 DepMap CRISPR Gene Dependency 1.0 2.73499 carboxy-lyase activity GO Molecular Function Annotations 2023 1.0 null response to progesterone GO Biological Process Annotations 2015 1.0 null regulation of primary metabolic process GO Biological Process Annotations 2015 1.0 null macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04488 DES_KO_GDS4804_171_mouse_young skeletal muscles GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.858237 cellular response to interferon-beta GO Biological Process Annotations 2015 1.0 null L1236 DepMap CRISPR Gene Dependency 1.0 5.84306 SW948 CCLE Cell Line Gene CNV Profiles 1.0 2.00774 CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_1455_KO_Cd14_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.08819 positive regulation of metabolic process GO Biological Process Annotations 2015 1.0 null SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.861259 YD8 CCLE Cell Line Gene CNV Profiles -1.0 -2.34172 regulation of response to wounding GO Biological Process Annotations 2015 1.0 null regulation of nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_776_KD_hsa_circ_0004287_SRP310189 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.74571 catabolic process GO Biological Process Annotations 2015 1.0 null bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048157 cycle GeneRIF Biological Term Annotations 1.0 null lipid metabolic process GO Biological Process Annotations 2015 1.0 null cellular response to oxygen-containing compound GO Biological Process Annotations 2015 1.0 null NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53034 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null regulation of innate immune response GO Biological Process Annotations 2023 1.0 null GATA1 ChEA Transcription Factor Targets 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08285 EVSAT DepMap CRISPR Gene Dependency 1.0 2.36874 negative regulation of type I interferon production GO Biological Process Annotations 2023 1.0 null regulation of sequence-specific dna binding transcription factor activity GO Biological Process Annotations 2015 1.0 null positive regulation of multi-organism process GO Biological Process Annotations 2015 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null regulation of signal transduction GO Biological Process Annotations 2015 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36898 phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.157973 Perturb_4802_KO_Mapk1_ERP004375 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.53703 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.520829 response to lipid GO Biological Process Annotations 2015 1.0 null DUSP1_KO_GDS1606_772_mouse_spleens GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SJRH30 COSMIC Cell Line Gene Mutation Profiles 1.0 null regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null Infertility, Male CTD Gene-Disease Associations 1.0 1.07696 negative regulation of sequence-specific dna binding transcription factor activity GO Biological Process Annotations 2015 1.0 null SN12C COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_16417_Mut_Gli2_SRP154383 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.71 regulation of type I interferon production GO Biological Process Annotations 2023 1.0 null cellular response to endogenous stimulus GO Biological Process Annotations 2015 1.0 null spleen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22246 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28809 WM115 DepMap CRISPR Gene Dependency 1.0 2.22834 lung GTEx Tissue Gene Expression Profiles 1.0 1.29728 sepsis GeneRIF Biological Term Annotations 1.0 null Perturb_15966_KO_Tbet_SRP063567 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.48786 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null cholecalciferol_mus musculus_gpl339_gse18993 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null negative regulation of response to external stimulus GO Biological Process Annotations 2023 1.0 null defense response to symbiont GO Biological Process Annotations 2023 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95099 regulation of antimicrobial humoral response GO Biological Process Annotations 2023 1.0 null differentially GeneRIF Biological Term Annotations 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LMO2 ChEA Transcription Factor Targets 1.0 null SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19368 Perturb_1499_KO_Ticam1_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.84655 Perturb_15677_KD_Srsf2_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08285 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835239 TAL1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null response to external stimulus GO Biological Process Annotations 2015 1.0 null microbody LOCATE Predicted Protein Localization Annotations 1.0 null response to molecule of bacterial origin GO Biological Process Annotations 2015 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_1445_KO_Irf3/Irf7_SRP221603 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.68274 lytic vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.132099 negative regulation of signal transduction GO Biological Process Annotations 2023 1.0 null Respiratory Hypersensitivity CTD Gene-Disease Associations 1.0 1.24056 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null positive regulation of response to biotic stimulus GO Biological Process Annotations 2015 1.0 null lysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.133699 furthermore GeneRIF Biological Term Annotations 1.0 null NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null aconitate decarboxylase activity GO Molecular Function Annotations 2015 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36623 TT2609C02 CCLE Cell Line Gene CNV Profiles 1.0 1.36724 COLO205 DepMap CRISPR Gene Dependency 1.0 3.75097 Perturb_1529_KO_Gpkow_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.02807 Perturb_1537_KO_Ly96_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.1401 crohn's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.245046 Perturb_1512_KO_Ash2l_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.33938 contributes GeneRIF Biological Term Annotations 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.68509 SCC9 CCLE Cell Line Gene CNV Profiles 1.0 2.53345 glia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.475812 adiposetissue BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07996 negative regulation of multicellular organismal process GO Biological Process Annotations 2015 1.0 null disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 JUN ENCODE Transcription Factor Targets 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.167326 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052053 Perturb_1858_KO_Nrf2_SRP371099 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 negative regulation of immune response GO Biological Process Annotations 2015 1.0 null fatty acid metabolic process GO Biological Process Annotations 2015 1.0 null carboxy-lyase activity GO Molecular Function Annotations 2015 1.0 null regulation of inflammatory response GO Biological Process Annotations 2023 1.0 null Perturb_1841_KO_Ifnar_SRP371304 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.43778 cellular response to organic cyclic compound GO Biological Process Annotations 2015 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCIH2291 CCLE Cell Line Gene CNV Profiles -1.0 -1.61685 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19368 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.19589 Perturb_17512_KO_Mll1_SRP067361 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.59205 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835239 TET2_KO_GDS4287_431_mouse_GMP - bone marrow progenitor population GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null inducible GeneRIF Biological Term Annotations 1.0 null MEIS1 ChEA Transcription Factor Targets 1.0 null HCC2157 CCLE Cell Line Gene CNV Profiles -1.0 -1.79534 response to tumor necrosis factor GO Biological Process Annotations 2023 1.0 null SW403 CCLE Cell Line Gene CNV Profiles 1.0 1.69949 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34353 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63241 intermediate GeneRIF Biological Term Annotations 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060796 response to progesterone GO Biological Process Annotations 2023 1.0 null NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null LYL1 ChEA Transcription Factor Targets 1.0 null NB5 DepMap CRISPR Gene Dependency 1.0 5.35728 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16842 GATA1_G1E-ER4_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72686 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058355 regulation of reactive oxygen species metabolic process GO Biological Process Annotations 2023 1.0 null Perturb_11998_KO_Tet2_SRP379840 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 hydro-lyase activity GO Molecular Function Annotations 2015 1.0 null a20 GeneRIF Biological Term Annotations 1.0 null FLI1 ChEA Transcription Factor Targets 1.0 null TAL1_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886249 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular response to ketone GO Biological Process Annotations 2023 1.0 null HSC2 CCLE Cell Line Gene Expression Profiles 1.0 1.53066 Perturb_15674_KD_Hnrnpu_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.418 enzyme GeneRIF Biological Term Annotations 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45188 Perturb_1446_KO_Tmem173_SRP221603 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.95551 GATA1_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061182 peroxisome LOCATE Predicted Protein Localization Annotations 1.0 null MFE319 CCLE Cell Line Gene Expression Profiles 1.0 1.79299 blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.09744 appendix HPA Tissue Gene Expression Profiles 1.0 1.87412 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69582 Learning Disorders CTD Gene-Disease Associations 1.0 1.11186 15845616-Table4 GeneSigDB Published Gene Signatures 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.472704 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null GFI1B ChEA Transcription Factor Targets 1.0 null 16166618-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null HS604T CCLE Cell Line Gene Expression Profiles 1.0 1.71372 NCIH2141 CCLE Cell Line Gene Expression Profiles -1.0 -2.5678 Perturb_2187_KO_Map3k7_SRP237503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.60991 DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74649 regulation of nucleic acid-templated transcription GO Biological Process Annotations 2015 1.0 null negative regulation of biological process GO Biological Process Annotations 2015 1.0 null CHP126 CCLE Cell Line Gene Expression Profiles -1.0 -1.74213 WSU-FSCCL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04937 decreased grip strength MGI Mouse Phenotype Associations 2023 1.0 null uterine epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.984122 SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.917902 SKUT1 CCLE Cell Line Gene CNV Profiles -1.0 -1.44014 regulation of inflammatory response GO Biological Process Annotations 2015 1.0 null spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03821 MXI1 ENCODE Transcription Factor Targets 1.0 null response to tumor necrosis factor GO Biological Process Annotations 2015 1.0 null NANOG ChEA Transcription Factor Targets 1.0 null regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.161 Perturb_1603_KO_Tlr4_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.51014 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231102 negative regulation of response to wounding GO Biological Process Annotations 2015 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.7161 GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null SARS-CoV MA15_Day4-TNFRsf1b KO_None_GSE40824 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.991981 OE33 CCLE Cell Line Gene CNV Profiles -1.0 -1.6757 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GATA1_G1E-ER4_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null obesity GWASdb SNP-Disease Associations 1.0 0.782562 CAL-78 COSMIC Cell Line Gene Mutation Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null Perturb_1909_KO_Phgdh_SRP303616 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GATA2 ChEA Transcription Factor Targets 1.0 null cellular response to progesterone stimulus GO Biological Process Annotations 2023 1.0 null NCIH1876 CCLE Cell Line Gene Expression Profiles -1.0 -3.05478 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45647 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null MECOM ChEA Transcription Factor Targets 1.0 null internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.252261 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058004 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.10341 mitochondrion GO Cellular Component Annotations 2015 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 antimicrobial GeneRIF Biological Term Annotations 1.0 null MET_knockout_263_GSE8747 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.10812 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellum HPA Tissue Protein Expression Profiles -1.0 -2.34145 Cognition Disorders CTD Gene-Disease Associations 1.0 1.06008 mRNA_RXRA_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950465 glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.096396 synthesizing GeneRIF Biological Term Annotations 1.0 null YT COSMIC Cell Line Gene Mutation Profiles 1.0 null PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21799 cellular response to hormone stimulus GO Biological Process Annotations 2015 1.0 null NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.79321 RCOR1 ENCODE Transcription Factor Targets 1.0 null growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.270379 Hepatitis B DisGeNET Gene-Disease Associations 1.0 null Perturb_11986_KO_Treml4_SRP249697 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.45738 TAL1 ChEA Transcription Factor Targets 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null acid GeneRIF Biological Term Annotations 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.344556 Perturb_15673_KD_Hnrnpk_SRP313287 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.73212 MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.146419 SKNSH DepMap CRISPR Gene Dependency 1.0 5.56499 uterus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.880778 melanoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.468824 aconitate decarboxylase activity GO Molecular Function Annotations 2023 1.0 null cellular GeneRIF Biological Term Annotations 1.0 null NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.998006 microglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.728975 DUSP1_KO_GDS1606_775_mouse_Spleens GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null icSARS CoV_12Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.01409 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212761 cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.035343 PU.1 MotifMap Predicted Transcription Factor Targets 1.0 null cellular response to type II interferon GO Biological Process Annotations 2023 1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ebolavirus(ZEBOV)_5day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.62988 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.173273 Perturb_12009_KD_EmbA_SRP361519 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.26961 adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.110972 dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.160714 cellular response to interleukin-1 GO Biological Process Annotations 2015 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null negative regulation of cytokine production GO Biological Process Annotations 2023 1.0 null SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.65084 GATA1_G1E-ER4_mm9_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04825 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 response to steroid hormone GO Biological Process Annotations 2015 1.0 null single organism reproductive process GO Biological Process Annotations 2015 1.0 null abnormal macrophage physiology MGI Mouse Phenotype Associations 2023 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.371982 positive regulation of reactive oxygen species metabolic process GO Biological Process Annotations 2023 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null positive regulation of response to external stimulus GO Biological Process Annotations 2015 1.0 null STK11_knockout_278_GSE34866 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.927732 EWS502 CCLE Cell Line Gene Expression Profiles -1.0 -1.70634 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34353 Perturb_11769_KO_Cd147_SRP364588 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.34193 16585964-SuppTable9 GeneSigDB Published Gene Signatures 1.0 null Perturb_9305_KO_Med16_SRP295417 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.945978 CA46 CCLE Cell Line Gene CNV Profiles 1.0 1.3782 17284527-TableS1 GeneSigDB Published Gene Signatures 1.0 null regulation of toll-like receptor 2 signaling pathway GO Biological Process Annotations 2015 1.0 null ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085195 ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null melanocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063479 Perturb_1254_KO_Man2a1_SRP268213 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.7482 Perturb_17565_KO_Drd5_SRP382345 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 thyroid GTEx Tissue Gene Expression Profiles -1.0 -1.51637 U87MG CCLE Cell Line Gene Expression Profiles 1.0 1.58981 Perturb_1558_KO_Ticam1_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.4242 regulation of molecular function GO Biological Process Annotations 2015 1.0 null overnutrition GWASdb SNP-Disease Associations 1.0 0.452769 regulation of defense response GO Biological Process Annotations 2015 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08285 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831645 KYSE520 CCLE Cell Line Gene CNV Profiles 1.0 1.76426 pbmcs GeneRIF Biological Term Annotations 1.0 null regulation of signaling GO Biological Process Annotations 2015 1.0 null CALU3 CCLE Cell Line Gene CNV Profiles -1.0 -1.33956 TAL1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -1.74764 single-organism metabolic process GO Biological Process Annotations 2015 1.0 null NCIH2023 CCLE Cell Line Gene CNV Profiles -1.0 -1.87229 VMRCRCW CCLE Cell Line Gene CNV Profiles -1.0 -1.51879 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.135974 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062804 cellular response to ketone GO Biological Process Annotations 2015 1.0 null OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.998006 positive regulation of response to external stimulus GO Biological Process Annotations 2023 1.0 null Perturb_1601_KO_Ticam2_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.22153 short-chain fatty acid metabolic process GO Biological Process Annotations 2015 1.0 null TAL1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42526 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.03766 Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null BT-474 COSMIC Cell Line Gene Mutation Profiles 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP2 CCLE Cell Line Gene CNV Profiles -1.0 -2.04358 Fibrosis CTD Gene-Disease Associations 1.0 1.30147 lyme disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.769618 organic acid catabolic process GO Biological Process Annotations 2015 1.0 null propionate catabolic process GO Biological Process Annotations 2015 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054977 Perturb_1620_KO_Cul3_SRP056432 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.697 Perturb_4457_OE_Atg7_SRP310882 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.33618 regulation of reactive oxygen species metabolic process GO Biological Process Annotations 2015 1.0 null arthritis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.12828 pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.067133 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.173018 response to lipopolysaccharide GO Biological Process Annotations 2015 1.0 null GATA1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular lipid catabolic process GO Biological Process Annotations 2015 1.0 null Perturb_9378_KO|KD_lincRNAEPS|PKR_SRP354151 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 NUDUL1 CCLE Cell Line Gene Expression Profiles 1.0 1.54087 ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069396 negative regulation of defense response GO Biological Process Annotations 2023 1.0 null Perturb_796_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 cellular metabolic process GO Biological Process Annotations 2015 1.0 null Perturb_17377_KD_E2f1/Myc/Pparg/Stat6_SRP190223 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.85118 Liver Diseases CTD Gene-Disease Associations 1.0 1.03715 regulation of immune response GO Biological Process Annotations 2015 1.0 null P31FUJ CCLE Cell Line Gene CNV Profiles 1.0 1.56477 reproductive process GO Biological Process Annotations 2015 1.0 null Perturb_17378_KD_Myc_SRP190223 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 KO52 CCLE Cell Line Gene CNV Profiles 1.0 1.5896 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19623