association	dataset	threshold value	standardized value
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00935
t70-white-adipose_male_2w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.41101
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
GSE234289_3_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94692
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41889
CARNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61068
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.848
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3821
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0941
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0333
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5968
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7357
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46738
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37568
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4214
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95001
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0892
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8597
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46718
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_A549_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15412
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80291
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF672	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20252
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01588
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06291
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101239_3_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07778
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30294
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29494
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.6302
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87314
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60848
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6655
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80672
PMC12606276-41698_2025_1121_MOESM1_ESM.pdf-25-JUND_JUND	Rummagene Transcription Factor Associations 2026	1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19505
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57622
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83288
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
chr7_31527239_A_C_b38	GTEx eQTL 2025	1.0	1.14323
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3219
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28354
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26532
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0047
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0279
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.48437
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22876
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.04498
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
HMG20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64166
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HSDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34264
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3318
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74304
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1746
LDAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07479
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-607-ENSG00000164600_NEUROD6	Rummagene Transcription Factor Associations 2026	1.0	null
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24025
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37139
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3773
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9605
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32824
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0269
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.223
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37889
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3055
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7136
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46259
CEP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94155
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02042
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1784
TXNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24028
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36212
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39994
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45273
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31886
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45471
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-158-NEUROD6_NEUROD6	Rummagene Transcription Factor Associations 2026	1.0	null
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38994
RIOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19133
ETV6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1424
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23514
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3284
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36448
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16774
NPAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27795
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9362
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18285
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1922
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32989
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5637
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13007
Papillary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21362
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12955
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5976
PEX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98534
ITGB1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52854
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6238
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31706
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62969
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56037
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13017
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05666
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1814
chr7_31547941_C_T_b38	GTEx eQTL 2025	1.0	2.35882
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00193
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27455
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5154
GSE153189_2_v_0_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8285
GSE196701_1_v_0_atorvastatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15106
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1061
496100304_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16241
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45579
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
SPNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40605
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03639
GSE126127_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9717
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.01538
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0136
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75357
increased mean platelet volume	IMPC Knockout Mouse Phenotypes	1.0	null
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01322
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01904
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
ATP5F1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02017
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10388
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47455
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52593
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6471
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
RGS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71152
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.09939
Astrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91609
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46689
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0506
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03107
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45118
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61813
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung acinar adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.704
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21196
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5678
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2108
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2669
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1472
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4302
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82576
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8327
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0287
GSE100217_1_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98223
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93698
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09664
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6928
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
GSE174383_2_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06672
SAMHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9993
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
SASS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64474
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8651
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16784
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83765
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59672
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8238
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47055
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83135
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3134
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25996
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12934
INTS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97501
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29065
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36671
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5035
SLC25A30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27047
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29154
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95759
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4316
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
Tn polyagglutination syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.352
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48033
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5735
CHST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53428
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05625
PAX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.12735
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18655
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1683
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39791
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-97-SOX14_SOX14	Rummagene Transcription Factor Associations 2026	1.0	null
OCRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23864
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36757
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57743
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03808
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
Brain_CT2_Astro 59	HuBMAP ASCT+B Annotations	1.0	null
GSE174383_6_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21463
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2021
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73704
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8865
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2641
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51614
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03312
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18157
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99887
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59453
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96508
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17459
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
increased basophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2024
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
PMC11997329-mmc1.pdf-1-HAND2_HAND2	Rummagene Transcription Factor Associations 2026	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10330983-ab-22-0432-Supplementary-Table-8.pdf-80-HSF5_HSF5	Rummagene Transcription Factor Associations 2026	1.0	null
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
TNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17189
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5763
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80554
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65144
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93107
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43212
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71769
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8351
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0656
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78109
HSFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17109
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0283
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7857
ASXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11779
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9706
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32402
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76581
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36016
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
TMEM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71473
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91428
PKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04792
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7169
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0101
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49855
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44772
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50485
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36667
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54207
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34546
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1427
FBXO44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30117
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01259
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39327
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.752
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37369
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8038
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27698
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88869
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.204
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
Telangiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8019
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8735
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25507
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52194
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5783
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63437
ZNF778	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83228
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64996
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72992
PMC8384902-mmc5.xlsx-H889_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29241
GSE148252_2_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7438
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99091
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23699
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84455
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40252
MRPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55379
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79122
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6431
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19948
ZNF75A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87774
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3667
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32387
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
Thorny excrescence	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.264
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44085
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3323
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.05799
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43397
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.79664
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6208
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89997
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
PMC6042247-NIHMS966841-supplement-Sup_Table_2.xlsx-Gene_Sets-FOXA2_FOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.67966
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31427
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2534
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9153
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.299
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02817
FAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45107
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0558
RES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29419
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
GSE229580_0_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17512
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6857
RPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69344
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33965
Lung papillary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.286
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5514
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67664
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66715
FNDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83312
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8781
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16831
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33848
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14027
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9012
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
increased eosinophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8804
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1395
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21742
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3406
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33034
decreased lymphocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41658
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32492
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.40331
GSE154074_5_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50608
Brain_CT2_Astro 59	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7847
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16102
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.72342
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57094
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3265
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78344
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00646
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3064
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4142
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09108
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7273
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54223
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5317
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12182
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
BBX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43136
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4024
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16342
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2596
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5935
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27187
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94505
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13377
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76442
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38919
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.797
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36653
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0213
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82867
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82668
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13964
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.6705
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06543
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
YWHAG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66729
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
ACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20104
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15998
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64174
GSE174383_1_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32989
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8025
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83437
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71722
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52868
EDA2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48615
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30951
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7752
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94949
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99659
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69241
ZWILCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61297
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57223
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85703
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9781
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87046
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1653
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46225
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13918
USP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18696
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6888
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2912
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38192
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33938
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0205
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15339
SOCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00165
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07048
Egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4658
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38718
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4617
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6173
Cajal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.104
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6925
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.121
GSE142684_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7917
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31772
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7502
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.921
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Psoriasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19677
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03206
HDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68745
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42539
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24832
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49037
increased neutrophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48855
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.3704
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7216
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61072
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.339
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34991
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7337
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02344
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4929
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
PCNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43415
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01203
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1974
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29807
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05578
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01177
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4521181-oncsis201520x8.pdf-141-ZGPAT_ZGPAT	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69684
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01168
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73074
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49348
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
colo829	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.994
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73781
PMC5637904-PATH-243-193-s016.xlsx-human_up_in_fat_SOX11-Table_S5A_Upregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30304
MAN2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37175
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33219
chr7_31547760_G_A_b38	GTEx eQTL 2025	1.0	2.45488
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59163
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9944
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.446
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08263
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9073
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2356
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7771
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7959
GSE153189_2_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85819
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57156
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.031
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64559
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0387
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89371
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3614
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
ONECUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38701
DBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11854
GSE169590_6_v_5_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9687
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2026
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54896
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68172
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
Psoriasis 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45941
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75944
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35004
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79739
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30643
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5561
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22373
CYP51A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6197
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8351
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2739
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6822
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44532
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65224
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37989
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3308
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6151
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98915
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7796
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51223
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.899
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46607
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33353
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55251
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
increased monocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87156
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54337
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
GSE85874_3_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PACSIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23486
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
LSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36044
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30338
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85931
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45295
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2122
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49562
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55557
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1862
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8153
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166536_0_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5853
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83691
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.56604
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8018
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25385
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41445
Psoriasis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8781
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX2-sequence_name_MSX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.41373
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
SPDEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4607
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60027
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23993
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15074
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20401
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38431
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0541
EN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43891
GPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47033
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84392
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Clear cell adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2778
HELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53669
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0572
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5614
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
GSE248668_1_v_0_atxn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08165
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.686
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61137
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1697
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.1155
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56239
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84001
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32401
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1177
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.0801
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.656
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06046
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52433
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16228
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43839
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32632
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1213
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19706
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03819
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03703
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99835
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.58566
SARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58551
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3501
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91713
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38016
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22583
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9398
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2303
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8037
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9602
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62719
MRTFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94999
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54673
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.261
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.429
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7693
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2296
TRMT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24779
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47933
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4762
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35978
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7937
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9907
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.399
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56941
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5844
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4919
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98661
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84164
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02287
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0831
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16319
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32366
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26397
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00077
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7683
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5576
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25308
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Slit-Robo signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6749
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SSBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9576
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC27A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83132
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34717
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0536
PRXL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79012
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67871
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63517
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874