association	dataset	threshold value	standardized value
regulation of monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6817
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939953
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08023
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35287
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04333
Syncope	DisGeNET Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938425
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080073
Familial atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054422
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01205
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61053
MAZ	ENCODE Transcription Factor Targets	1.0	null
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.355
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991543
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870975
Acute Chest Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2411
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.62463
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941275
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825276
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
TBP	ENCODE Transcription Factor Targets	1.0	null
Astrocyte_Embryonic prefrontal cortex_Human	CellMarker Gene-Cell Type Associations	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.1665
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3968
MV411	CCLE Cell Line Gene Expression Profiles	1.0	2.66587
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442962
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.886627
H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37702
GSE62843,GSE64371_2_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glomerulopathy Assessment	DisGeNET Gene-Phenotype Associations	1.0	null
relevant	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35001
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155025
T24	BioGPS Cell Line Gene Expression Profiles	1.0	0.912666
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830027
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
t-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.364331
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07012
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.84289
positive regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02844
ekg, abnormal	GAD Gene-Disease Associations	1.0	null
potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38827
action potential	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4308	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
SW1463	DepMap CRISPR Gene Dependency	1.0	4.66964
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58748
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84633
Neuron	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.26176
Megalocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
regulation of potassium ion export across plasma membrane	GO Biological Process Annotations 2023	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10722
Depressed Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28675
atrial cardiac muscle cell action potential	GO Biological Process Annotations 2023	1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76014
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62496
negative regulation of potassium ion transport	GO Biological Process Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39032
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3003
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
SPI1	ChEA Transcription Factor Targets	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825797
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.80276
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80471
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76147
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04808
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041586
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68071
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.2705
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
voltage-gated potassium channel complex	GO Cellular Component Annotations 2023	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95872
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895797
Disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
hsa-miR-4510	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
striated muscle contraction	GO Biological Process Annotations 2015	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.994552
Perturb_1066_KO_Esr1_SRP087718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.29824
Brugada Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6434
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIAML2	CCLE Cell Line Gene Expression Profiles	1.0	3.20695
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.36768
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3198	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8519
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36558
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67305
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0088
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869356
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868702
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
abnormality of the nephron	HPO Gene-Disease Associations	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.702308
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.747285
Perturb_9565_KO_Cdx2_SRP149724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41408
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86828
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MONOMAC6	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.927
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	3.15306
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851392
Long QT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.748
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35429
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30043
GATA2	ENCODE Transcription Factor Targets	1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83762
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.5508
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41627
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919946
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
hsa-miR-593	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17802
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14514
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
regulation of blood circulation	GO Biological Process Annotations 2015	1.0	null
Ventricular Arrhythmia	DisGeNET Gene-Disease Associations	1.0	null
Bone_Marrow-hematopoietic stem cell	Tabula Sapiens Gene-Cell Associations	1.0	4.01763
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829281
negative regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284262
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836381
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.909668
Lung-dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.10464
PMC10290283-biol-2022-0622-sm3.pdf-448-BSX_BSX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13536
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885734
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964399
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100450_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16736
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69268
CBX3	ENCODE Transcription Factor Targets	1.0	null
Elliptocytosis	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
Cardiac arrest	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042
hsa-miR-4419a	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22346
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068753
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.79125
Stellate ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922276
hsa-miR-2682	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20966
hypokalemic periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00161
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.39076
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38869
PK8	DepMap CRISPR Gene Dependency	1.0	2.21042
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-608	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_3145_KO_Mrfta/Mrtfb_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70574
SIN3A	ENCODE Transcription Factor Targets	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985881
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85086
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8261
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828922
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25133
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33935
AMME complex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.585
C10	DepMap CRISPR Gene Dependency	1.0	2.16201
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06247
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49092
anemia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13324
regulation of blood circulation	GO Biological Process Annotations 2023	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46544
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.36768
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.396353
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95515
cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858931
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49941
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9177
metal ion transport	GO Biological Process Annotations 2015	1.0	null
thick vermilion border	HPO Gene-Disease Associations	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
specific developmental disorder	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.20947
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188632
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.56258
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923294
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40366
regulation of potassium ion export across plasma membrane	GO Biological Process Annotations 2025	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910374
regulation of atrial cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2025	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3305
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9518
Alport Syndrome, Mental Retardation, Midface Hypoplasia, And Elliptocytosis	DisGeNET Gene-Disease Associations	1.0	null
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.75
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00343
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51863
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090438
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858199
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.521023
NCI-H1299	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53735
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
modulates	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL6	CCLE Cell Line Gene Expression Profiles	1.0	1.34771
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04931
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01013
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01311
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45248
Proteinuria	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2826
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.5174
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68437
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11216
abnormality of the heart valves	HPO Gene-Disease Associations	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8554
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5896
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8993
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06318
voltage-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08375
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-1526-SM-3LK7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904509
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898303
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6985
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09695
bronchus	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47658
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862001
GTEX-XGQ4-1226-SM-4AT67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08549
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KU812	CCLE Cell Line Gene Expression Profiles	1.0	1.42391
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8037
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05773
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18157
Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062528
WM115	DepMap CRISPR Gene Dependency	1.0	3.44489
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01631
UPCISCC111	DepMap CRISPR Gene Dependency	1.0	4.23365
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.9577
Tcof1_OE_GDS998_154_mouse_neuroblastoma N1E-115 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07868
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16261
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884317
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MDAMB231_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24231
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50143
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3563
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06349
fibrillation	GeneRIF Biological Term Annotations	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861903
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53402
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03869
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30147
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04731
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01805
hsa-miR-3178	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
negative regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23391
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33374
abnormality of the glomerulus	HPO Gene-Disease Associations	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.609
EW-3	GDSC Cell Line Gene Expression Profiles	1.0	1.59467
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of potassium ion export across plasma membrane	GO Biological Process Annotations 2023	1.0	null
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
hemolytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05578
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
upregulated	GeneRIF Biological Term Annotations	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of system process	GO Biological Process Annotations 2015	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MGAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29704
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	1.2942
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
CMAH_KO_GDS4200_114_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
voltage-gated potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34827
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.612
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924784
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7858
KDM4A	ENCODE Transcription Factor Targets	1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.40272
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10424
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
malar flattening	HPO Gene-Disease Associations	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28223
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29518
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17756
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25932
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827624
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911058
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.13279
SIGM5	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60346
cardiac conduction	GO Biological Process Annotations 2025	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65493
Perturb_4159_KO_Mir137_SRP072457	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.4162
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053627
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828922
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06582
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.39006
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single	GeneRIF Biological Term Annotations	1.0	null
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0036
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903789
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4584_KO_Socs3_SRP099234	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.59411
GTEX-UJHI-1026-SM-4IHJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56107
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9892
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
negative regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.109635
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26172
tapered finger	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09373
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.7333
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01393
CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.97013
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885189
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Gastric dilatation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11483
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.768
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5462
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830727
GSE148494,GSE182513_1_v_0_hoxd13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-555	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.738
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125696
Heart conduction disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
familial periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.911845
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integral component of nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.532
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-BRF2_BRF2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05168
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99867
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42324
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898399
neuroblast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10071
NIHOVCAR3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59911
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
Long QT syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496874
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394408
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859711
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02517
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06437
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01805
Perturb_13742_KO_Nfib_SRP096738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34107
Perturb_4583_KO_Socs3_SRP074146	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.59411
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50416
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05069
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abnormality Of The Metaphysis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0397
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33474
slanting of the palpebral fissure	HPO Gene-Disease Associations	1.0	null
regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
negative regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.999
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1226
Acute Coronary Syndrome	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.306
Perturb_15620_KO_Net39_SRP273304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17947
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
regulation of atrial cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2023	1.0	null
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03119
496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59644
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.55046
AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04046
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967221
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
Usher syndrome type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61502
18231642-TableW1	GeneSigDB Published Gene Signatures	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66841
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0589
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02799
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10876
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874545
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.36012
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058817
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69237
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES-D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.479
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Microscopic Hematuria	DisGeNET Gene-Phenotype Associations	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57822
regulation of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843452
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95337
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01805
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14252
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889118
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32598
downslanted palpebral fissures	HPO Gene-Disease Associations	1.0	null
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.693311
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09866
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12629
potassium channel regulator activity	GO Molecular Function Annotations 2015	1.0	null
Alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.859087
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44181
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887225
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.168236
Perturb_6342_KO_LONP1/ATF4_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.0458
PMC11257629-media-9.xls-METTL3_KD_upregulated_Genes-METTL3KD_UPregulated_Genes_1694_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75115
TUR	GDSC Cell Line Gene Expression Profiles	1.0	1.52752
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.579661
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
immune system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.017
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE172494_2_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.23414
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044664
KPNYS	DepMap CRISPR Gene Dependency	1.0	5.24966
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049827
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8171
action potential	GO Biological Process Annotations 2015	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22279
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1748
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6659
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5437
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26641
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420004
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.39427
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00751
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11735
abnormality of long bone morphology	HPO Gene-Disease Associations	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.953208
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
regulation of metal ion transport	GO Biological Process Annotations 2015	1.0	null
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
strabismus	HPO Gene-Disease Associations	1.0	null
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37269
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074105
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0766
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23882
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09024
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73669
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2494
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33661
deafness-intellectual disability, Martin-Probst type syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
potassium ion export across plasma membrane	GO Biological Process Annotations 2023	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970615
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
skin	HPA Tissue Protein Expression Profiles	1.0	1.02146
CAL29	DepMap CRISPR Gene Dependency	1.0	2.32077
Rectum adenocarcinoma_READ_TCGA-AH-6897-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Patent Ductus Arteriosus	DisGeNET Gene-Disease Associations	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09493
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849698
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08085
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85146
fallopian tube	HPA Tissue Gene Expression Profiles	-1.0	-0.860332
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.33091
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.804
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48993
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12903452-mmc5.xlsx-ST2-2_OCT4_Off_Targets-Target_Gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.04308
hsa-miR-4482	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00579
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart contraction	GO Biological Process Annotations 2023	1.0	null
voltage-gated potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2704
abnormality of cells of the erythroid lineage	HPO Gene-Disease Associations	1.0	null
UMUC11	DepMap CRISPR Gene Dependency	1.0	11.5334
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25028
abnormality of the midface	HPO Gene-Disease Associations	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53851
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051366
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12292
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.977761
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGGT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23757
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13411
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995479
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85815
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane repolarization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914036
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882875
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042592
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932363
Perturb_15778_KO_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57545
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4764-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
brs	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36577
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50677
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09836
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985215
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876135
Perturb_8598_KO_Arid1a_SRP312002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.63762
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Long QT syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.276
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of blood and blood-forming tissues	HPO Gene-Disease Associations	1.0	null
KPL1	DepMap CRISPR Gene Dependency	1.0	2.30076
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59646
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	0.834184
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87198
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22411
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851378
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.85761
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14919
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49241
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
SH2B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52575
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
brugada syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.36422
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36143
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4082
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166319
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00424
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.4182
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53539
regulation of heart contraction	GO Biological Process Annotations 2023	1.0	null
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27112
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42536
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939145
GSE143782_6_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51325
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
expressions	GeneRIF Biological Term Annotations	1.0	null
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13962
patent ductus arteriosus	HPO Gene-Disease Associations	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848996
hsa-miR-2861	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.286519
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55722
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37861
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
depressed nasal bridge	HPO Gene-Disease Associations	1.0	null
WDR53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0948
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77462
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Type 1 diabetes mellitus_Thymic epithelial cell_GSE11	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48832
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
first-degree atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30311
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
17597811-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.822
screening	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885825
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859241
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85552
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910771
Cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.077
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835423
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6363
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of voltage-gated potassium channel activity	GO Biological Process Annotations 2023	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092815
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Long QT syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.099
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42428
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86576
ecg	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.93794
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01805
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213833
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
potassium channel regulator activity	GO Molecular Function Annotations 2023	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37474
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.60641
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936882
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.27311
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24671
positive regulation of potassium ion transport	GO Biological Process Annotations 2025	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55815
Perturb_3146_KO_Mrfta/Mrtfb/Myocd_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.4979
mRNA_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04893
abnormality of digit	HPO Gene-Disease Associations	1.0	null
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMRC1	CCLE Cell Line Gene Expression Profiles	1.0	1.866
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04547
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29106
voltage-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.697
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2092
I band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
GSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54797
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869531
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951741
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61548
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16021
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057109
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55206
Rheumatic heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GTEX-QCQG-1426-SM-48U22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02824
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12475
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89432
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00855
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.50602
HCT116	DepMap CRISPR Gene Dependency	1.0	2.68963
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96985
thyrotoxicosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.566831
SF268	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00401
MAPK14_knockout_13_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.02347
regulation of delayed rectifier potassium channel activity	GO Biological Process Annotations 2023	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.81413
system process	GO Biological Process Annotations 2015	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.97472
GSE199543,GSE239447_2_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
atrial cardiac muscle cell to AV node cell signaling	GO Biological Process Annotations 2023	1.0	null
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17745
hsa-miR-2278	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24149
regulation of ventricular cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2025	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.045136
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_259_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19666
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32044
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.73533
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00878
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04642
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.645
regulation of cation channel activity	GO Biological Process Annotations 2023	1.0	null
hsa-miR-760	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.51078
NB13	DepMap CRISPR Gene Dependency	1.0	2.04311
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.898354
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853968
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.7516
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1193
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.37
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944157
18316601-Table1	GeneSigDB Published Gene Signatures	1.0	null
LN18	CCLE Cell Line Gene Expression Profiles	1.0	1.70609
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82098
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32062
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82245
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879172
SPRYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43304
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62029
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10809
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03031
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58199
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873895
Atrial Fibrillation	HuGE Navigator Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940015
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045083
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34457
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67196
voltage-gated potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71607
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828449
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327483
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16917
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38126
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
preeclampsia	GeneRIF Biological Term Annotations	1.0	null
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826064
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-16.9885
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.73177
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.33236
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997498
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
ankyrin-B-related cardiac arrhythmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
brain	GTEx Tissue Gene Expression Profiles	1.0	1.80184
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41577
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17475_KO_Ubr4_SRP259313	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.68293
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90111
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850384
cognitive impairment	HPO Gene-Disease Associations	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5638
positive regulation of cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Atrial heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
SKGI	DepMap CRISPR Gene Dependency	1.0	2.58487
NOMO-1	GDSC Cell Line Gene Expression Profiles	1.0	2.57944
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05747
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20575
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.721
Perturb_9498_KO_Lsd1_SRP096254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.36685
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Tooth, Supernumerary	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17597811-SuppTable7	GeneSigDB Published Gene Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17055
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08007
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Phase 2 - plateau phase	Reactome Pathways 2024	1.0	null
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54262
gainoffunction	GeneRIF Biological Term Annotations	1.0	null
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.693
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957769
GTEX-UPIC-1726-SM-4IHKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
Perturb_15296_KO_Ash2l_SRP212178	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.7696
cardiac muscle cell action potential involved in contraction	GO Biological Process Annotations 2015	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02669
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.2708
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850967
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.908786
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16476
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05291
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
CP67-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.80264
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4741	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04179
Perturb_2240_KO_L2hgdh_SRP093280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64993
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963254
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991543
X-linked Alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.56195
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962331
FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
forms	GeneRIF Biological Term Annotations	1.0	null
GTEx AdiposeTissue 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-7.13751
PANC0403	CCLE Cell Line Gene CNV Profiles	1.0	1.32983
regulation of heart rate	GO Biological Process Annotations 2015	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30938
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945916
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.298214
negative regulation of potassium ion export across plasma membrane	GO Biological Process Annotations 2025	1.0	null
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
proxymetacaine-3113	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17871
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14088
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.912885
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08253
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49419
SHSY5Y	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30313
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77678
NCI H226	BioGPS Cell Line Gene Expression Profiles	1.0	1.20562
Perturb_6340_KO_Nrtn_SRP273435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.01187
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931491
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905902
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16689
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
NO36	DepMap CRISPR Gene Dependency	1.0	2.04969
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2694
nordihydroguaiaretic acid-2683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	7.09169
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87341
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12569
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.61078
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6415
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970019
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84721
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09611
Cardiac conduction	Reactome Pathways 2024	1.0	null
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JHH6	CCLE Cell Line Gene Expression Profiles	1.0	1.53752
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.961177
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832058
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15877
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.058
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15314
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46065
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.025
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51973
single-organism transport	GO Biological Process Annotations 2015	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3781
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
right ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88016
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944861
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thin Lips	DisGeNET Gene-Phenotype Associations	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.236862
cardiac muscle contraction	GO Biological Process Annotations 2023	1.0	null
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07113
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
malar anomaly	HPO Gene-Disease Associations	1.0	null
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
delayed rectifier potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04352
EB-3	GDSC Cell Line Gene Expression Profiles	1.0	1.4591
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
regulation of heart contraction	GO Biological Process Annotations 2025	1.0	null
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051359
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14422
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT549	CCLE Cell Line Gene CNV Profiles	1.0	1.53518
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52296
KINGS1	DepMap CRISPR Gene Dependency	1.0	2.11893
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06215
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.681155
Brugada syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.047
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71775
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.902832
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868371
Timothy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
GSE85874_3_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01396
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84649
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3130-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.65399
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
prednisolone_homo sapiens_gpl570_gse32962	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL2094 (MSH2)	NURSA Protein Complexes	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
COGN305	DepMap CRISPR Gene Dependency	1.0	4.65345
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.44662
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appeared	GeneRIF Biological Term Annotations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
hsa-miR-3202	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Perturb_8559_OE_Snca_SRP102360	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.9745
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051429
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59455
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43495
TCCPAN2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69403
RET_knockout_270_GSE32093	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.00243
negative regulation of transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965083
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7536
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57831
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
Supraventricular Tachycardia	DisGeNET Gene-Disease Associations	1.0	null
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3214
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45547
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LAMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06184
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
common	GeneRIF Biological Term Annotations	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.958591
647V	CCLE Cell Line Gene Expression Profiles	1.0	1.40222
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE180185_4_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L363	DepMap CRISPR Gene Dependency	1.0	3.36538
developmental disorder of mental health	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NCI-SNU-5	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.61078
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25935
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949064
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18208
CL-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.42789
NSMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15958
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.788
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906599
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6025
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825764
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06612
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82746
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056994
potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50525
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2779
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hematopoietic system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.843091
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31941
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03915
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.27525
639-V	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51816
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
membrane repolarization	GO Biological Process Annotations 2023	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57029
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
neuron	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
coronary	GeneRIF Biological Term Annotations	1.0	null
Paroxysmal Familial Ventricular Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4503
hsa-miR-654-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07627
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0502
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10582
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO Molecular Function Annotations 2023	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	5.22953
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
hsa-miR-2355-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
X-linked deafness 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE450	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61184
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29103
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969995
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47975
Bmi-1_KD_GDS2724_102_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870996
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41068
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.396
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85086
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829875
congenital malformation of the great arteries	HPO Gene-Disease Associations	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905857
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	1.69345
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04339
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.70014
PMC10795826-jciinsight-8-170518-s128.xlsx-Fig_5B-Gene_Regulated_by_VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55841
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905201
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.957718
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64432
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44413
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nerve	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85447
RSV-A2_24Hour-KO_RSV_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7786
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.796
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9394
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06241
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845982
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0063
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the metaphyses	HPO Gene-Disease Associations	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6224-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990827
muscular hypotonia	HPO Gene-Disease Associations	1.0	null
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7678
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	2.1648
Thoracic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.574
PMC7921413-41467_2021_21650_MOESM5_ESM.xlsx-002_DE-CD34_Blasts_AP1_low_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
Long QT Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE227891_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56356
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.566054
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891202
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71039
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53444
channel regulator activity	GO Molecular Function Annotations 2015	1.0	null
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.53346
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837425
Perturb_4423_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7771
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052976
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486326
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20311
regulation of atrial cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2015	1.0	null
Muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
hsa-miR-3158-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897383
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13837
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99614
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88719
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
PMC4029819-pone.0098069.s005.xlsx-FOXA1-Table_S4_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_ER_negative_samples_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59964
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00632
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6691
placenta	HPA Tissue Protein Expression Profiles	1.0	1.70014
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.03329
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938533
normocytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
congenital hemolytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
COGN278	DepMap CRISPR Gene Dependency	1.0	4.57744
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
TBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35593
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.51953
MERO82	DepMap CRISPR Gene Dependency	1.0	2.86158
Perturb_14122_KD_Tcf4_SRP061034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PMC12301693-ALZ-21-e70505-s001.xlsx-ST12-Unnamed_13_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.871923
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
Long QT syndrome 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179633
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
potassium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48937
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896649
CASKI	DepMap CRISPR Gene Dependency	1.0	2.78851
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913187
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48598
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.68505
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50262
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16645
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40911
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55362
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45564
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.91503
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35428
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871225
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46259
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	3.03733
acquired	GeneRIF Biological Term Annotations	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32683
Andersen-Tawil syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of transmembrane transporter activity	GO Biological Process Annotations 2015	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44846
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78737
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874878
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8529
SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054629
SNU478	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43358
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50272
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5609
GSE222445_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
negative regulation of potassium ion transport	GO Biological Process Annotations 2015	1.0	null
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42452
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888463
Myopia	DisGeNET Gene-Disease Associations	1.0	null
Nodal receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
colon	GTEx Tissue Gene Expression Profiles	-1.0	-0.833734
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
GMNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60919
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41757
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904301
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961481
non-syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
especially	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841037
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31426
quadriplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.882292
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897549
gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314409
cyclopentolate-6132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GAMG	DepMap CRISPR Gene Dependency	1.0	3.0171
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23762
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58921
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30261
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071674
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059375
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900768
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53851
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889365
abnormality of bone marrow cell morphology	HPO Gene-Disease Associations	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42771
regulation of heart rate by cardiac conduction	GO Biological Process Annotations 2023	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.111
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1632
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.16985
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937852
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49762
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21955
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72945
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00859
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40617
potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.13543
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.12969
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61246
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892248
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.836831
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065213
blood	GTEx Tissue Gene Expression Profiles	1.0	0.965597
Phase 3 - rapid repolarisation	Reactome Pathways 2024	1.0	null
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	GO Molecular Function Annotations 2015	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7169
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
cellular potassium ion transport	GO Biological Process Annotations 2015	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214742
Right Bundle Branch Block	DisGeNET Gene-Disease Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54692
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844437
E12	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52635
abnormality of the head	HPO Gene-Disease Associations	1.0	null
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07815
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15851
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CV-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.08007
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94687
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966889
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01888
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069655
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.965664
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5ST-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4194
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21458
abnormality of the nasal alae	HPO Gene-Disease Associations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15237
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066933
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05599
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	3.06475
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921789
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U937	CCLE Cell Line Gene Expression Profiles	1.0	1.87284
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60071
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35171
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
Long QT syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.126
heart contraction	GO Biological Process Annotations 2025	1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52598
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWCY-1426-SM-48TCT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964842
regulation of monoatomic ion transmembrane transporter activity	GO Biological Process Annotations 2023	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18785
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21487
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.24205
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
NCIH1618	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7243
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7067
abnormality of the lip	HPO Gene-Disease Associations	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58837
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
membrane part	GO Cellular Component Annotations 2015	1.0	null
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2205
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166920_6_v_2_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50471
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
Perturb_12974_KO_IGF2BP2_SRP365416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
atrial	GeneRIF Biological Term Annotations	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53929
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-1.27311
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.75777
PPARA_KO_GDS2886_484_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02521
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61836
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7083
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890816
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.077
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5052
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04973
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5944
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904404
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19494
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95175
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06776
Perturb_1232_KD_PCBP2_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.00376
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888654
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974355
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11147
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46819
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26073
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.16475
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21684
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5527
MyoD	MotifMap Predicted Transcription Factor Targets	1.0	null
FFAR4_KO_GDS4811_507_mouse_adipose	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.92892
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33956
cardiac muscle cell action potential involved in contraction	GO Biological Process Annotations 2025	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB4	CCLE Cell Line Gene Expression Profiles	1.0	1.81369
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.86028
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
delayed rectifier potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02775
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.13729
15869706-Table3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972378
Nkx-2.5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382966
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.81009
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31327
hsa-miR-4480	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
atrial cardiac muscle cell to AV node cell signaling	GO Biological Process Annotations 2025	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857641
protein complex	GO Cellular Component Annotations 2015	1.0	null
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29781
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06961
sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175466
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5468
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04243
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular cardiac muscle cell action potential	GO Biological Process Annotations 2015	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56291
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40113
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32137
Long Qt Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27996
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striated muscle contraction	GO Biological Process Annotations 2025	1.0	null
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0357
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7114
Phospholamban complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
NEC8	GDSC Cell Line Gene Expression Profiles	1.0	1.72085
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76447
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3135b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05894
Long QT syndrome 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898303
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of erythrocytes	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4091
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918818
hsa-miR-4468	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28325
hsa-miR-1827	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13262
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10341
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863021
proteinuria	HPO Gene-Disease Associations	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04911
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980445
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379499
15869706-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979233
meptazinol-2906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
variants	GeneRIF Biological Term Annotations	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65337
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833313
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23373
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856454
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12602
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37258
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60296
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.22653
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40055
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45878
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01942
PPARA_Deficiency_GDS2934_632_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912796
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
potassium ion export	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
abnormality of lower lip	HPO Gene-Disease Associations	1.0	null
17597811-SuppTable9	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91776
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544946
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16705
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
thick lower lip vermilion	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94285
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5699
regulation of potassium ion transport	GO Biological Process Annotations 2023	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
SGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83122
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30412
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03272
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06466
Perturb_8536_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.32295
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13183
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Corpora quadrigemina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
OVCA420	DepMap CRISPR Gene Dependency	1.0	3.11425
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43906
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_fMSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	2.00702
hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415024
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.563238
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37238
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20991
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1582
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054743
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ito	GeneRIF Biological Term Annotations	1.0	null
tsA-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21237
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07318
OVCAR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46984
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936186
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41423
PMC2694838-1471-2164-10-241-S3.xls-Sheet1-Commonly_altered_genes_by_ZNF191_overexpression_and_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10725
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
GFAP_OE_GDS1488_255_mouse_Olfactory bulb of  4 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09765
Perturb_5502_Mut|KO_Hras_SRP026484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96926
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969723
Paroxysmal Ventricular Tachycardia	DisGeNET Gene-Disease Associations	1.0	null
RTRAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86635
metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140527
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12867
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	201.357
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18047
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03578
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05759
FU97	DepMap CRISPR Gene Dependency	1.0	2.26426
ventricular cardiac muscle cell action potential	GO Biological Process Annotations 2023	1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16193
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968326
embryo	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052878
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01575
single organism signaling	GO Biological Process Annotations 2015	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34435
regulation of potassium ion transport	GO Biological Process Annotations 2015	1.0	null
OCI-AML2	GDSC Cell Line Gene Expression Profiles	1.0	3.25408
voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	GO Molecular Function Annotations 2025	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57837
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054428
Sinoatrial node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.267
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8289
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5672
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0271
Corpus cavernosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31779
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930112
all	HPO Gene-Disease Associations	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2451
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19104
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.19732
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93913
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922324
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927341
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842883
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20161
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056982
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60772
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88785
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838724
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01203
MDAMB415	DepMap CRISPR Gene Dependency	1.0	2.46406
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.64474
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26971
atrial cardiac muscle cell action potential	GO Biological Process Annotations 2025	1.0	null
voltage-gated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936835
regulation of ventricular cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2015	1.0	null
hnf1a_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.10059
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139335
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40274
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04969
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136812
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929459
alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.690293
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01954
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844872
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41403
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
Perturb_6175_OE_Zeb1_SRP187711	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.51978
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.83858
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5302
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Premature Ventricular Contractions	DisGeNET Gene-Phenotype Associations	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07048
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904307
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842379
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95233
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36377
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4894
St Segment Elevation (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158951
mRNA_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09017
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875199
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13914
MONO-MAC-6	GDSC Cell Line Gene Expression Profiles	1.0	2.30399
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55062
nerve	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2585
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.61046
WEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31799
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.727288
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64434
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.694
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66431
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5216
PBX1	ChEA Transcription Factor Targets	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
CSTB_KO_GDS5090_199_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
ion channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
abnormal facial shape	HPO Gene-Disease Associations	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	6.45695
atrial cardiac muscle cell action potential	GO Biological Process Annotations 2015	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0683
rectum	HPA Tissue Gene Expression Profiles	-1.0	-0.860332
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00314
male	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47778
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13102
hypoplastic facial bones	HPO Gene-Disease Associations	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21858
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945043
Anemia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
myopia	HPO Gene-Disease Associations	1.0	null
abnormal number of teeth	HPO Gene-Disease Associations	1.0	null
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
acetylcholine-gated channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the nares	HPO Gene-Disease Associations	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05325
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18291
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.78729
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982467
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849698
E2F1	ChEA Transcription Factor Targets	1.0	null
DETROIT562	CCLE Cell Line Gene CNV Profiles	1.0	1.50202
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885189
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40195
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
Perturb_4158_KO_Mir137_SRP072457	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.2681
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02577
negative regulation of delayed rectifier potassium channel activity	GO Biological Process Annotations 2023	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14929
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42996
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07981
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
Middle cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.59362
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98264
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.904
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5023
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.36012
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08157
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiac muscle contraction	GO Biological Process Annotations 2015	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885089
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RET_mutant_23_GDS3319	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.56442
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865385
medial orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856312
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MONOMAC1	CCLE Cell Line Gene Expression Profiles	1.0	2.40883
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18183
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937797
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88296
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05499
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874749
hsa-miR-1234	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC-78	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.61078
Perturb_13763_KO_Uqcrq_SRP284268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.91805
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02749
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02779
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
nucleotide	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941162
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
kcne5	GeneRIF Biological Term Annotations	1.0	null
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	0.928428
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51936
NOMO1	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.2925
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4516
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26811
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_8-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
multicellular organismal signaling	GO Biological Process Annotations 2015	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068195
Perturb_15774_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.6406
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07477
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053939
UM-UC-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.61078
rectum	HPA Tissue Protein Expression Profiles	1.0	1.70014
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930596
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45584
ACHE_OE_GDS891_241_mouse_Prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_8535_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.40102
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00048
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63767
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11253
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
APP	Pathway Commons Protein-Protein Interactions	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945491
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19404
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991543
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981977
Cardiac Arrest	DisGeNET Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43743
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18693
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5422
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39363
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	GO Molecular Function Annotations 2023	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09378
RBBP5	ENCODE Transcription Factor Targets	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.891107
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Short QT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.638
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98977
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931892
membrane repolarization during action potential	GO Biological Process Annotations 2025	1.0	null
Perturb_9752_KO_Rnf20/Rnf40_SRP228497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
hearing impairment	HPO Gene-Disease Associations	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23987
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9495
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elliptocytosis	DisGeNET Gene-Phenotype Associations	1.0	null
NPRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24331
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
survival	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
positive regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39965
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02194
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20621
hsa-miR-2467-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
CARMIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13064
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166884
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84967
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38763
cardiac muscle cell action potential involved in contraction	GO Biological Process Annotations 2023	1.0	null
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
CAMA1	DepMap CRISPR Gene Dependency	1.0	3.70174
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266069
regulation of ion transmembrane transporter activity	GO Biological Process Annotations 2015	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955009
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63936
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7069-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4757-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
cho-k1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126183
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7246
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
HT144	DepMap CRISPR Gene Dependency	1.0	6.70575
AIRE_KO_GDS2274_245_mouse_Medullary thymic epithelial cells (with low CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.662329
disease of mental health	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
positive regulation of potassium ion transport	GO Biological Process Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
ACHE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65626
Downward Slant Of Palpebral Fissure	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21827
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03464
positive regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19467
MYL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4111
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6034
GSU	DepMap CRISPR Gene Dependency	1.0	3.35996
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.927
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825361
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I2-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Catecholaminergic polymorphic ventricular tachycardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22041
EPLC-272H	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5487
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0024
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.85784
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
thin vermilion border	HPO Gene-Disease Associations	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84749
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08733
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0617
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837803
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57858
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825955
PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
Long QT syndrome 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
cause	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06862
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69795
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.047
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
snp	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27668
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-9_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.828922
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07829
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.57904
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151622
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890647
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8793
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30403
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061784
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37886
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066933
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.838888
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71822
GATA1	ENCODE Transcription Factor Targets	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	1.0	0.968956
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12797
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02321
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0472
CHD1	ENCODE Transcription Factor Targets	1.0	null
deafness-dystonia-optic neuronopathy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02202
positive regulation of cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.284
Long QT syndrome 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-556-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4675	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
regulation of transporter activity	GO Biological Process Annotations 2015	1.0	null
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008736
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.395
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.377621
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	212.4
regulation of heart rate by cardiac conduction	GO Biological Process Annotations 2025	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043812
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.001
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.747285
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960339
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2672
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
increased number of teeth	HPO Gene-Disease Associations	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836369
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cardiac muscle cell action potential	GO Biological Process Annotations 2015	1.0	null
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0726
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alport syndrome	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.36414
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.75678
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Cardiovascular system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
renal insufficiency	HPO Gene-Disease Associations	1.0	null
regulation of potassium ion transport	GO Biological Process Annotations 2025	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.913853
PMC7806814-41598_2020_80145_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_S4_X-linked_genes_differentially_expressed_in_response_to_LPS_in_males_only_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071682
SW1463	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0565
Perturb_15777_KO_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165493
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46871
Hematopoietic system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4225
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064092
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89226
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.50595
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.19681
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905365
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0928
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828335
PHF8	ENCODE Transcription Factor Targets	1.0	null
Mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.319
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ONS76	CCLE Cell Line Gene Expression Profiles	1.0	1.71762
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30077
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888314
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.355
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02394
Left ventricular noncompaction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04117
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960339
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893872
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
NCIH841	CCLE Cell Line Gene CNV Profiles	1.0	3.09524
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868971
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10911
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842914
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882436
H1_Derived_Neuronal_Progenitor_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.24957
positive regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
CA-60-LK14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.260207
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.49667
CCK81	DepMap CRISPR Gene Dependency	1.0	2.50673
Perturb_11479_KO_Ring1_SRP321271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7604
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10809
regulation of transport	GO Biological Process Annotations 2015	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964416
regulation of cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2023	1.0	null
FRTL-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53125
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18721
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
postacute	GeneRIF Biological Term Annotations	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.625
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828689
Brugada syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05965
hela	HPA Cell Line Gene Expression Profiles	1.0	0.886317
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76147
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Tongue-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	2.78195
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849339
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2025	1.0	null
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98491
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977559
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
kidney	HPA Tissue Protein Expression Profiles	-1.0	-1.44662
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53564
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965561
TR146	DepMap CRISPR Gene Dependency	1.0	2.36434
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939145
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51749
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29917
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87155
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21984
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81134
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.55706
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39563
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855738
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899012
Thick Vermilion Border	DisGeNET Gene-Phenotype Associations	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-7-TBX2_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951562
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.829
RCM1	DepMap CRISPR Gene Dependency	1.0	2.08754
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28348
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947258
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09288
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976429
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55012
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901559
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866986
Alport syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Right ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876021
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.954103
nonfamilial	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994625
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
hsa-miR-449c	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72525
membrane repolarization	GO Biological Process Annotations 2025	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19384
a549	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	0.875785
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.76701
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.290462
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.9443
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895967
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08455
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	1.0	1.0241
IM9	DepMap CRISPR Gene Dependency	1.0	3.36321
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73374
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.937917
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08501
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.156845
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936882
GTEX-WEY5-1226-SM-4LMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212608
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09735
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.87834
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10878
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.944
positive regulation of potassium ion transport	GO Biological Process Annotations 2023	1.0	null
glomerulopathy	HPO Gene-Disease Associations	1.0	null
regulation of blood circulation	GO Biological Process Annotations 2025	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943426
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924253
TE-6	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59018
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.432646
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069243
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83356
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06033
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
MOTN1	CCLE Cell Line Gene Expression Profiles	1.0	1.53495
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827624
transporter complex	GO Cellular Component Annotations 2015	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278179
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20984
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.868552
hsa-miR-626	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
Wolff-Parkinson-White syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
syndrome	GeneRIF Biological Term Annotations	1.0	null
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4894
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74367
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05024
membrane repolarization during action potential	GO Biological Process Annotations 2015	1.0	null
8305C	CCLE Cell Line Gene Expression Profiles	1.0	1.35235
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hemolytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40974
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28462
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01336
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.93761
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24743
HDAC6	ENCODE Transcription Factor Targets	1.0	null
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834179
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17925
gastric outlet obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.881472
positive regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17645
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906688
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237465
Ventricular Tachycardia, Polymorphic	DisGeNET Gene-Disease Associations	1.0	null
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28162
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.05451
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06283
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40354
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897902
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19773
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15851
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895978
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32177
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39505
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Cardiomyopathy, Hypertrophic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hypokalemic periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987445
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884546
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
MFM-223	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93563
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896643
Muscle contraction	Reactome Pathways 2024	1.0	null
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06191
Hyperthyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2126-SM-4BOOX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	310.526
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01113
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35527
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pulmonary venous myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
Arrhythmogenic right ventricular cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.128
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17291
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852067
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	192.091
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94789
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.099072
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881773
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133651
HDAC2	ENCODE Transcription Factor Targets	1.0	null
striated muscle contraction	GO Biological Process Annotations 2023	1.0	null
voltage-gated cation channel activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
HL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07465
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064157
effects	GeneRIF Biological Term Annotations	1.0	null
negative regulation of potassium ion transport	GO Biological Process Annotations 2025	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBFA2T3_KD_GDS4045_458_human_Non-Hodgkin's lymphoma Reh cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PWN1-1526-SM-48TDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110477
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Severe Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Familial periodic paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954282
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.829635
intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.467306
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870805
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0695
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11814291-41698_2025_830_MOESM1_ESM.pdf-3-ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
MKN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78928
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
OVMIU	DepMap CRISPR Gene Dependency	1.0	4.17189
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	6.00871
PMC5823716-onc2017356x6.xlsx-350POS_noreps_txt-Supplementary_Table_4_ESC_SNAI1_FLK1hi_UP_Human_orthologs_of_top_350_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074764
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
cardiac conduction	GO Biological Process Annotations 2023	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72847
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32442
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Right bundle branch block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.286
potassium channel complex	GO Cellular Component Annotations 2023	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990993
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04176
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31191
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972547
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.61643
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87995
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
First Degree Atrioventricular Block	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07013
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65827
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68629
Bone_Marrow-granulocyte	Tabula Sapiens Gene-Cell Associations	1.0	6.07711
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055058
CTV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.646
ivf	GeneRIF Biological Term Annotations	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.679
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PATU8902	DepMap CRISPR Gene Dependency	1.0	3.95744
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
acute	GeneRIF Biological Term Annotations	1.0	null
intellectual disability	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29223
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54017
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4688
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77403
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37289
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.65753
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34204
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07796
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37583
polymorphism	GeneRIF Biological Term Annotations	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058643
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
Congenital hemolytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6366
Sick Sinus Syndrome	DisGeNET Gene-Disease Associations	1.0	null
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06276
cardiac muscle contraction	GO Biological Process Annotations 2025	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8271
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.783557
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76029
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
16109776-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959321
hereditary elliptocytosis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1339	CCLE Cell Line Gene Expression Profiles	1.0	1.45613
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23276
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12759
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851182
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.005
Usher syndrome type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83015
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04859
Abnormality Of Aortic Valve	DisGeNET Gene-Disease Associations	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0097
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13329
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of heart rate by cardiac conduction	GO Biological Process Annotations 2015	1.0	null
kcnq3	GeneRIF Biological Term Annotations	1.0	null
Cystic Fibrosis_Pancreas_GSE769	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.927924
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33358
Huntington's Disease_Brain_GSE3621	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.43964
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.783972
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.96842
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97531
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MTF2	ChEA Transcription Factor Targets	1.0	null
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56553
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13191
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906738
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.35567
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0512
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851288
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscle contraction	GO Biological Process Annotations 2015	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mesopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
HT1376	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74356
regulation of potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898303
E2F4	ENCODE Transcription Factor Targets	1.0	null
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85325
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.650439
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50043
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.356314
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40457
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24788
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07492
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932075
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.70014
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1057
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of membrane repolarization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15237
potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26231
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25557
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.59775
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24104
abnormality of finger	HPO Gene-Disease Associations	1.0	null
Rmz	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
PEO4	DepMap CRISPR Gene Dependency	1.0	2.29783
Lymph_Node-hematopoietic stem cell	Tabula Sapiens Gene-Cell Associations	1.0	0.241938
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24857
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane repolarization during cardiac muscle cell action potential	GO Biological Process Annotations 2015	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10944
negative regulation of cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09936
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054118
ion channel binding	GO Molecular Function Annotations 2015	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24663
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58983
hyperthyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162707
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
Long QT syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.245
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane repolarization during action potential	GO Biological Process Annotations 2023	1.0	null
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34848
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.518034
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0777
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13741_KO_Nfia_SRP096738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.81045
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.972195
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09139
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09396
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0645
hsa-miR-4254	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
channel activity	GO Molecular Function Annotations 2015	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	3.17514
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.47625
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18907
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832767
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16972
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Tapering Fingers (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
measurements	GeneRIF Biological Term Annotations	1.0	null
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842467
RPMI7951	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3236
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216933
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Sudden infant death syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043646
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18169
long fingers	HPO Gene-Disease Associations	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18793
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837974
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35292
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07494
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventricular cardiac muscle cell action potential	GO Biological Process Annotations 2025	1.0	null
hsa-miR-4671-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ibrs2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
Perturb_6335_KO_MLL4SET_SRP221512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.1547
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CAKI-1	GDSC Cell Line Gene Expression Profiles	1.0	1.52081
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48503
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979792
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32282
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
regulation of monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07285
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67208
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.987976
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25499
z disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383124
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97612
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3774
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
Heart disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
cation channel complex	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4274	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839559
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997048
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
familial atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.57305
cardiac conduction	GO Biological Process Annotations 2015	1.0	null
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19917
mRNA_SMARCA4_22196727	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05509
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09532
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.851335
PMC4271336-13041_2014_88_MOESM6_ESM.xlsx-Genes_in_GENE_CARD_MR_or_ID-Gene_Cards_MR_and_ID_genes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856353
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
voltage-gated potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03977
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03739
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.94
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919476
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20097
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950439
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04695
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ntera2	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
atrial fibrillation	GAD Gene-Disease Associations	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-NFK9-1626-SM-3LK5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824493
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ECC4	DepMap CRISPR Gene Dependency	1.0	3.2926
BRD-K49328571_dasatinib_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCA1_Knock-in_GDS3544_561_mouse_Cerebellum - 4 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
UPF1_Deficiency_GDS2781_188_human_HeLa cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary elliptocytosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39497
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34958
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052504
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4091
regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08628
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02449
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12587
GSE166920_6_v_4_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
regulation of ventricular cardiac muscle cell membrane repolarization	GO Biological Process Annotations 2023	1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48369
ion transport	GO Biological Process Annotations 2015	1.0	null
regulation of heart contraction	GO Biological Process Annotations 2015	1.0	null
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
i band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.350243
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32197
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
Normocytic anemia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87208
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14505
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59728
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898688
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22716
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954097
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04814
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92896
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU-65	GDSC Cell Line Gene Expression Profiles	1.0	1.69164
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1617
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4305
hematuria	HPO Gene-Disease Associations	1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21672
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28613
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0776
regulation of cation channel activity	GO Biological Process Annotations 2015	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04253
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5035
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.85249
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28307
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
Long QT syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
action potential	GO Biological Process Annotations 2025	1.0	null
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.45917
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14626
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054446
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48183
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18974
hsa-miR-320e	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01541
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0523
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53252
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849039
Intrinsic component of nuclear inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.488
missense	GeneRIF Biological Term Annotations	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.9598
SAP30	ENCODE Transcription Factor Targets	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
PRKCZ_KO_GDS4310_293_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_4179_KO_Tsc1_SRP279018	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.46531
Perturb_5503_OE_Hras_SRP026484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.9119
KCNH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12246
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988899
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.908074
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897597
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.2464
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0925
GTEX-V1D1-1726-SM-4JBHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10659
Trifascicular Block	DisGeNET Gene-Disease Associations	1.0	null
Myosin XVI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.457
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.464283
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042194
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.928
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867743
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14015
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827624
Contiguous Gene Syndrome	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the aortic valve	HPO Gene-Disease Associations	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29446
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0292
Restrictive cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Arcus senilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894262
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15411
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19195
pyloric stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.961216
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539793
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17759_KO_Lin9_SRP221087	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.4868
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
Perturb_8534_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.2647
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.823989
SNU308	CCLE Cell Line Gene CNV Profiles	1.0	1.4597
Long QT syndrome 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
CSTB_KO_GDS5090_398_mouse_cerebella	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
abnormal urine cytology	HPO Gene-Disease Associations	1.0	null
NCI-H510A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46976
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943345
Daudi	GDSC Cell Line Gene Expression Profiles	1.0	1.74029
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7418
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09205
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22044
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054997
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91462
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499223
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H357	DepMap CRISPR Gene Dependency	1.0	2.03879
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	4.50366
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5296
frontal operculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886116
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29229
Malar Flattening	DisGeNET Gene-Disease Associations	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.462239
potassium channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
Brugada syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Ventricular Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09906
potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
XBP1_OE_GDS2861_60_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04961
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.701167
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1425
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.095814
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860996
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02394
muscle system process	GO Biological Process Annotations 2015	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
MPP89	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6285
Long QT syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.5
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11753
negative regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33849
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964829
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
abnormality of the zygomatic arch	HPO Gene-Disease Associations	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55909
potassium ion export across plasma membrane	GO Biological Process Annotations 2025	1.0	null
voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	GO Molecular Function Annotations 2025	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67649
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.346409
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Jervell-Lange Nielsen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.973
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.851
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.999102
Sick sinus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.271
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866941
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HE-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
long qt syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26516
voltage-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
JHUEM7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84993
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052063
oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
SKES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56464
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.703
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75504
hsa-miR-4651	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
ZNF384	ENCODE Transcription Factor Targets	1.0	null
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5292
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03019
heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30707
intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192344
GNG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0206
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05169
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
GSE158595_0_v_1_e4f1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964968
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44018
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055852
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04947
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989854
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.09407
potassium ion transport	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anteverted nares	HPO Gene-Disease Associations	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967425
hsa-miR-4685-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
SKOV3	DepMap CRISPR Gene Dependency	1.0	2.03293
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62016
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.45535
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
cation transport	GO Biological Process Annotations 2015	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.842254
Av Block First Degree By Ecg Finding	DisGeNET Gene-Phenotype Associations	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953281
Cardiac muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23919
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18586
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.15425
hsa-miR-4309	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26589
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-922	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
third-degree atrioventricular block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989773
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41375
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18025
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10401
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6153
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
hsa-miR-31	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.98889
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46792
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06261