association	dataset	threshold value	standardized value
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16643
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77Q-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.136
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31743
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.01396
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74381
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90157
BRD-K16560691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56449
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42467
Bladder-plasmacytoid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.18575
Integration of energy metabolism	Reactome Pathways 2014	1.0	null
Detrusor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907265
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117606
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02605
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18691415-Table5d	GeneSigDB Published Gene Signatures	1.0	null
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25115
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056608
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864689
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5719
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32713
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86217
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3442
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30257
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K13402127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20603
potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60851
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990965
BRD-K86070914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09012
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0746
BRD-K15410616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60126
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34678
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99699
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27387
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874877
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
GSE150032,GSE181873_3_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994634
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56112
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27576
abnormality of the uterus	GWASdb SNP-Phenotype Associations	1.0	0.425272
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05098
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10062
BRD-K85697068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26293
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23332
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08281
M059K	DepMap CRISPR Gene Dependency	1.0	2.04536
NCI-H650	GDSC Cell Line Gene Expression Profiles	1.0	1.56877
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4387
Bladder wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46516
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.85244
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.36874
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9456
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32022
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10748141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07438
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49724
Visual areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33313
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32518
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44351
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26104
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TIMM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35715
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44405
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18933
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBL1_KO_GDS1932_739_mouse_Neurospheres	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95316
central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
786	BioGPS Cell Line Gene Expression Profiles	1.0	1.182
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28439
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1QB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41456
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909795
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18115
BRD-K61050695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57614
DG-75	GDSC Cell Line Gene Expression Profiles	1.0	1.97688
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38357
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15963
Perturb_7976_KO_Npm1/Smc3_SRP337222	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.83826
H3K36me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850237
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79768
BRD-K18494310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61553
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5993
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20044
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05481
Lassa fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04595
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07396
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.861
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26986
CRCGN015_HEPG2_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11727
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0779
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0385
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51574
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3014
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.957
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08014
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80087
BRD-K26461918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3385
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23415
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046571
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09736
pulmonary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433757
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062137
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.936071
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Reactome Pathways 2014	1.0	null
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03877
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3476
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42505
KCL22	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23157
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946558
SNCA_KO_GDS4153_445_mouse_Striatum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52761
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97198
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34113
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.101931
BRD-K80622681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67394
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20306
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993125
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05485
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992017
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00659
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31667
Opioid sensitivity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28254
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33676
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33275
SLR26	CCLE Cell Line Gene Expression Profiles	1.0	1.67973
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58584
BRD-K33064989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05005
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07779
BRD-K40088786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44939
CRCGN015_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04119
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30643
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289199
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37019
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29867
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83562499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73292
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07753
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04736
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881363
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07212
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.569
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45939
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.36874
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37336973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09066
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20207
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85047
amyotrophic lateral sclerosis	GWASdb SNP-Phenotype Associations	1.0	1.38847
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123739
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832261
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00381
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60981
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2135
CD55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27008
HSC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41428
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52392
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842834
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167915
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77957
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862391
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
energy derivation by oxidation of organic compounds	GO Biological Process Annotations 2015	1.0	null
BRD-K82176569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11018
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.08709
decreased circulating serum albumin level	MGI Mouse Phenotype Associations 2023	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06046
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890955
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874279
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.04112
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.643828
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ATP5PB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82158
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43308
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30153
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05641
EP300	ENCODE Transcription Factor Targets	1.0	null
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32561
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63647
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48812
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.829107
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
BRD-K51335814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13941
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94807
PMC7347220__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.194401
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.77688
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15714
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81507
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18198
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42253
EW8	CCLE Cell Line Gene Expression Profiles	1.0	2.48633
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7186
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PTK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95954
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11216188-peerj-12-17616-s013.pdf-300-ZNF236_ZNF236	Rummagene Transcription Factor Associations 2026	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00321
CRCGN009_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04279
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K09977699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20293
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.67636
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72237
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41383
AMIFAMPRIDINE PHOSPHATE	DGIdb Drug Targets 2026	1.0	0.22055
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
BRD-K24639784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57887
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03246
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36331
NCIH2126	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5256
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62937
PMC7347220__F5	PFOCR Pathway Figure Associations 2024	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01108
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066404
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81229
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86861
BRD-K90863245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69461
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03246
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
disease	GWASdb SNP-Disease Associations	1.0	0.034456
Purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37121
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.26917
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905007
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57936
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94542
BA-86-AL61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.4032
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56485
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03246
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04237
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77618
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.877344
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24234
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62011
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41109
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18857
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344818
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981242
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13928
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12164
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92758
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41699
Kleptomania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01098
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32472782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1166
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68438
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_3_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02383
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08422
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
brain	HPA Tissue Gene Expression Profiles	1.0	1.11007
BRD-K75844451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13744
fleroxacin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58259
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1434
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06658
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874279
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2977
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.43628
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.57176
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28134
PMC11462941-CAS-115-2947-s001.pdf-150-LBX2-AS1_LBX2	Rummagene Transcription Factor Associations 2026	1.0	null
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13971
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31296
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298731
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45094
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15636
FBXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18699
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K97748657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39586
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
BRD-K63987422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08174
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
abnormality of female internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.133596
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
voltage-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02436
Perturb_4708_KD_Dnmt3b_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.5229
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.338
KARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88446
umbilical vein endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17223
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.485119
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81133
Rheaume et al.Nat Commun.39_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866221
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832469
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13911
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34982
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	1.182
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.1466
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93975
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71222
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49838
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80895
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21183
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.302168
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3948
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PRKACG	Pathway Commons Protein-Protein Interactions	1.0	null
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18549
CRCGN011_HEPG2_24H:J02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5429
CDS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29139
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40485
regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
MCC13	DepMap CRISPR Gene Dependency	1.0	2.40853
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.26514
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04565
ARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98874
Secondary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19715
FOXP3_ABLATION_GDS2525_64_mouse_mature regulatory T cells (Treg)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040862
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-11A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01345
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07778
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
action potential	GO Biological Process Annotations 2025	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97457
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24242
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4896
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11758
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.20371
BRD-K35560933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05771
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
PMC5495879__F3	PFOCR Pathway Figure Associations 2023	1.0	null
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61451
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29148
BRD-K38446773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4425
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1047
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977927
BRD-K35936801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14104
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48373
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6516
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85205
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25354
LOXL2_KD_GSE35600_688_human_MDA-MB-231 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	5.012
BRD-K93496326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37395
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44976
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17193
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Piriform area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23235
CRCGN013_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18764
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53776
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.251476
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55918
HL60	CCLE Cell Line Gene CNV Profiles	1.0	1.48618
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64509
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23978
dichlorophen	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01709
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15976
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06816
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
UTP-C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97411
BRD-K53241408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76159
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6281
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45998
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.531
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057703
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41248
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20479
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.030612
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57438
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3603
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.62199
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79252
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integration of energy metabolism	Reactome Pathways 2024	1.0	null
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54952
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11082
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058176
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00277
CRCGN009_HEPG2_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05042
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18839
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35542
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
EN	CCLE Cell Line Gene Expression Profiles	1.0	1.38379
Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43531
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13086
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68563
NAXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86721
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02675
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12846
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71695
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893903
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949598
BRD-K25757224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65009
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29022
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051456
BRD-K38450726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89815
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03932
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999807
H357	DepMap CRISPR Gene Dependency	1.0	2.20982
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32685
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67814
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27568
GSE201309_4_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21751
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04414
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.124807
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862555
regulation of insulin secretion	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K32159948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06483
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	208.471
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78492
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49685
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08191
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.753
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8093
BRD-K67430561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03766
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49570068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60947
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86086
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	1.40265
BRD-K73834056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76063
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
intermediate stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35765
BRD-K45936761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4335
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37757
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846255
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9264
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65974
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17079
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
BRD-K99131664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39052
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1668
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55835
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825553
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935006
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11873
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05968
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05182
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93002
18689800-TableS8	GeneSigDB Published Gene Signatures	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21588
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969844
BRD-K05041276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02239
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.51618
BRD-K20454972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32126
BRD-K52148119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96888
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1754
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44125
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7065
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34783
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13289
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12022
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09657
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976917
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19507
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46169
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16076
RELA_01_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63938
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25866
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88613
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30553
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31537
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PMC11747033-Table1.xlsx-Sup_Table_S1-IFNy_LPS_TREATED_HMEC_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
HCC515	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865615
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5381
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.20823
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08021
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2497
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47978
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51851
BRD-K04614055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29108
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09009
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32577
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.99486
Perturb_8389_KO_Rnaseh1_SRP108593	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.35897
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.815
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K35386584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81571
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53128
SUDHL8	DepMap CRISPR Gene Dependency	1.0	6.02513
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02276
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10124
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77726
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902724
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88412
CCFSTTG1	DepMap CRISPR Gene Dependency	1.0	2.80176
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3663
potassium ion transport	GO Biological Process Annotations 2015	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83509
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02116
Bone_Marrow-hematopoietic stem cell	Tabula Sapiens Gene-Cell Associations	1.0	0.415205
BRD-K73430970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76833
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881555
GSE235707,GSE235712_1_v_0_ctbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28414977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74726
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02661
delayed rectifier potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870659
CAKI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3611
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.16296
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09952
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48761
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03172
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20522
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0636
female reproductive system disease	GWASdb SNP-Disease Associations	1.0	0.198189
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3588
G-401	GDSC Cell Line Gene Expression Profiles	1.0	2.50609
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.7171
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1732
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.753
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33306
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01189
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80961
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824932
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876857
LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K79547691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3683
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27825
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03314
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69727
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.81934
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34615
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
NCO2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59747
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824121
Sarcoma_SARC_TCGA-DX-A2J4-01A-32R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A_KD_GDS4759_340_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
LMSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60209
HCC1599	GDSC Cell Line Gene Expression Profiles	1.0	1.52236
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05186
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82332
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.072429
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48168
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78964
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054758
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14708
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	202.592
ITGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1826
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856314
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27695
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44558
Endopiriform nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07277
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49753
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02605
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02049
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922173
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5624
GABPA	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39444
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.05312
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
BRD-K77518191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17004
BRD-K33350866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24936
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
potassium ion transport	GO Biological Process Annotations 2025	1.0	null
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36176133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0301
LS1034	DepMap CRISPR Gene Dependency	1.0	3.32544
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.936
BRD-K83494171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11402
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63758740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39286
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66824
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01117
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21022
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62188824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20341
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08365
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41298
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31239
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79778
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87967
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4256
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	1.38266
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41721
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50791
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19292
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21856
BRD-K39543844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07726
BRD-K70357895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14251
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21183
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06968
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04633
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31377965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20515
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14969
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41818
SR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.1
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18159
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57201
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.5529
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39447
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40326
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841387
CRCGN017_MCF10A.WT.HP_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54803
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45535
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.773
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10607_KO_Kcnj8_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.74304
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.989774
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47875
BRD-K47275094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89111
U343	CCLE Cell Line Gene Expression Profiles	1.0	2.00881
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5431-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04886976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02899
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
em3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68257
BTB/POZ fold	InterPro Predicted Protein Domain Annotations	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32505
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32802
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.26218
BRD-K46820725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52747
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANC0403	CCLE Cell Line Gene Expression Profiles	1.0	2.1808
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62585
Ion transport domain	InterPro Predicted Protein Domain Annotations	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4888
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.90378
C80	DepMap CRISPR Gene Dependency	1.0	2.69781
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80281
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.241
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15643
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92435
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01485
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41259
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	1.39315
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3954
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26678
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05897
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-IRF1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50251
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	4.2753
Secondary motor area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10157
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
neurodegenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45501
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82829
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	5.23382
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33726
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30929
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24993
BRD-K04443775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05536
BRD-K84118789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29786
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19308
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879205
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Opioid-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0607
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3462
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.68979
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9471
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.46847
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25021
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35782
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14885
BRD-K98170574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37616
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5381
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045364
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858149
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04271
CRCGN016_MCF10A.TP53.M_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19089
GSE210101,GSE210114_1_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67596
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
18691415-Table5f	GeneSigDB Published Gene Signatures	1.0	null
BRD-K26272845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93778
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068343
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18146
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77015
BRD-K43484052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05316
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83705
pimosertib	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20144
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00475
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33277
EXOSC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27456
BRD-K00300115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56439
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32119
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878015
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00174
Perturb_7005_KO_Slc14a1_SRP310250	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.12835
CE-15-YU05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275313
BRD-K92484282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26586
Regulation of insulin secretion	Reactome Pathways 2024	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31325
Schwartz-Jampel syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04225
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.850557
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18627
DOHH-2	GDSC Cell Line Gene Expression Profiles	1.0	1.96867
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8192
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03632
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.66935
Perturb_10606_KO_Abcc9_SRP132855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.99331
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04254
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02649
BRD-K89668690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33255
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB_01_238	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.20282
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936773
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8958
BRD-K30772101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4019
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13254
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0712
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
decreased cardiac stroke volume	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894213
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
CRCGN010_HEPG2_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03777
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50275
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28449
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0555
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0103
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81923
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42673
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65529782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29812
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66183
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
SKNDZ	DepMap CRISPR Gene Dependency	1.0	4.16588
A4-Fuk	GDSC Cell Line Gene Expression Profiles	1.0	1.586
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	3.47375
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7109_OE_Sirt5_SRP364867	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97293
all	GWASdb SNP-Phenotype Associations	1.0	0.034421
GTEX-R55C-0726-SM-48FCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837623
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.273
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46447
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
PDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82919
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K51790412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35284
umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192125
MORCPR	CCLE Cell Line Gene Expression Profiles	1.0	1.35009
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041243
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081511
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7219-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18473
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056087
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895535
SF767	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53527
SF295	GDSC Cell Line Gene Expression Profiles	-1.0	-2.49161
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865314
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.3359
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.78155
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.33887
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6863
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6358
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072032
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
BRD-K03770502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30612
Sinoatrial node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-K56272400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06903
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11095
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
Electrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45308
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28161
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830307
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14419
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06694
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55023
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938265
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03646
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092213
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62937
KCNB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36577
Dentate gyrus mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26498
Perturb_7057_KO_Sod2_ERP107154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.80649
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4690-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4313
Lung adenocarcinoma_LUAD_TCGA-05-4398-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K32214429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15243
BRD-K75745696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78601
HCC44	CCLE Cell Line Gene Expression Profiles	1.0	1.35857
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03813
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Clobetasol propionate_NCI-H460	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0125705
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25073
SLR20	CCLE Cell Line Gene Expression Profiles	1.0	1.57043
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02203
endometriosis	GWASdb SNP-Disease Associations	1.0	0.498059
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
ATXN7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36515
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Pyromania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
H3K9me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08925
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24987
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77694
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14957
BRD-K31479652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11475
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67122
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2683
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21086
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62117
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24202
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83777
BRD-K01225799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12611
regulation of peptide transport	GO Biological Process Annotations 2015	1.0	null
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.53303
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42912
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09234
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97073
Lung adenocarcinoma_LUAD_TCGA-73-7498-01A-12R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2496
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70509
voltage-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04901
pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.768197
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931335
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830406
Cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
BRD-K20039572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47618
TUR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050613
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.00551
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.36767
NB13	DepMap CRISPR Gene Dependency	1.0	7.57952
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54901
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26347
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.72154
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10079
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.59851
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LIN28B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30613
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19164
Lung adenocarcinoma_LUAD_TCGA-78-8648-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87152
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16871
BRD-K86694287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36301
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83988
abnormality of the genital system	GWASdb SNP-Phenotype Associations	1.0	0.07559
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2124
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995188
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06862
8505C	CCLE Cell Line Gene Expression Profiles	-1.0	-2.82125
LU-134-A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42329
Perturb_10618_Mut_Ttn_SRP272110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32567
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14249
NCIH2030	DepMap CRISPR Gene Dependency	1.0	2.44723
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71122
SBC-5	GDSC Cell Line Gene Expression Profiles	1.0	1.4387
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29636
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45812
BRD-K51270604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59295
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16338
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076825
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.85984
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3821
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862352
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	3.4632
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45955
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055767
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24059
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07884
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38591
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906169
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03246
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50021
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82906
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0795
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903854
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884624
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SBC-1	GDSC Cell Line Gene Expression Profiles	1.0	2.34989
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64669
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93517
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33459
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11829
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96635
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15758
huvec cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
BRD-K67898193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76145
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	0.902812
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77841
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58146
Perturb_10616_KO_Ttn_SRP136441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.75077
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64368
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22405104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48864
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923264
TRPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10458
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07867
HNF4A_KD_GSE29084_694_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13319
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17193
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88978
BRD-K59314947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17551
Lung adenocarcinoma_LUAD_TCGA-05-4395-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864728
CRCGN017_MCF10A.TP53.M_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40056
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49008
CRCGN009_HEPG2_24H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36291
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50286
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10447
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.894346
PDSS2_KO_GDS3454_120_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48089
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27727
cation transport	GO Biological Process Annotations 2015	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09285
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15228
Perturb_11953_OE_Casz1_SRP332232	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	1.58755
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831205
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936386
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25651
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13103
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J2-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50265
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1337
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866821
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bcor_22012066_cn_aml_lof_human_gpl570_gds4280	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.205492
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK115	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45358
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38097
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02293
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.581
regulation of protein localization	GO Biological Process Annotations 2015	1.0	null
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61083
Perturb_6982_KO_Nlrp3_SRP173143	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.68054
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25814
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.299197
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35952
Human - Motor Cortex - Cluster - FEZF2+ CSN1S1+ Layer 5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878524
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27262
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052658
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01988
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09559
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11483
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05194
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3052
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29257
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64822
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.75632
decreased cardiac muscle contractility	IMPC Knockout Mouse Phenotypes	1.0	null
Mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tribenoside-3507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47945
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2819
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09633
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11873
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921925
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08365
Perturb_6531_KO_C1galt1c1_SRP184497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.53788
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53801
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15666
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905148
GAMG	DepMap CRISPR Gene Dependency	1.0	2.43916
T3M5	DepMap CRISPR Gene Dependency	1.0	2.42049
CTCF	ENCODE Transcription Factor Targets	1.0	null
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05319
LI7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50908
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6955
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
CALU3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58611
BRD-K04441230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46225
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16288
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54948591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02049
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40098
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06257
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924932
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830343
voltage-gated cation channel activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K45621617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28025
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34646
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44316
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PMC6938365-pone.0226733.s020.txt--ESR1_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Voltage-gated potassium channel	InterPro Predicted Protein Domain Annotations	1.0	null
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865836
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13419
DC-81-PH69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.503514
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10697
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50122
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1819
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05021
KMS26	DepMap CRISPR Gene Dependency	1.0	4.03646
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45037
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13909
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.59504
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39364
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24059
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
BRD-K75281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19583
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46924
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.31564
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12141
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78349
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6306
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.58109
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11878
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24538
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.18797
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24643
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60115
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8655-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71766
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10366
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24548
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15077
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042238
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079701
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2663
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53912
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41289356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85518
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36073
ranolazine_mus musculus_gpl1261_gse25767	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046498
Number of sexual partners	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
TP63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18161
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Heroin dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17029
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85746
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869096
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008736
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29652
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62867
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17178
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05387
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36328
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amyotrophic lateral sclerosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
energy reserve metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TC-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852855
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890351
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96092
BRD-K37283718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10289
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0962
NFATC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03076
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882433
HS895T	CCLE Cell Line Gene Expression Profiles	1.0	1.41655
Potassium channel, voltage dependent, Kv6	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28023
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11525
hl60	HPA Cell Line Gene Expression Profiles	1.0	0.844291
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25108
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19462
Neuronal System	Reactome Pathways 2024	1.0	null
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64635
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
cephalothin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43813
urinary bladder smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49114
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03911
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093395
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040319
BxPC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.55162
BRD-K75845970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11022
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22694
SOX2	ChEA Transcription Factor Targets	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929521
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.322
BRD-K29264158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04542
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.933808
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908006
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87221
PLCPRF5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39076
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85237
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986266
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3017_KD_Ttn_SRP222910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.43106
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01052
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949162
MYBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4262
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89848
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04235
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416521
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888591
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79628
SNCA_KO_GDS4153_530_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hallucinogen dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
NCI-H378	GDSC Cell Line Gene Expression Profiles	1.0	2.27515
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63042
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
WDR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12738
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14381
PCI-15A	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31667
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.874619
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14639
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.33001
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0767
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	0.966722
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06451
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01203
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62976536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12767
LIVF001-008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27282
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.10955
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48258
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57594
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	2.41463
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851519
motor neuron disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48427
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984372
GSE215351,GSE215794_7_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09960817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3771
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66235
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59031
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-2.10541
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3499
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.29125
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.194548
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051277
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88978
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946748
Lung adenocarcinoma_LUAD_TCGA-73-4668-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST486	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80385
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12164
metal ion transport	GO Biological Process Annotations 2023	1.0	null
H3K27me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02674
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29206
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935235
SNU899	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65646
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02203
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39567
membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76685
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	2.61158
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08515
CAL72	DepMap CRISPR Gene Dependency	1.0	3.33177
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93847
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36682
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083367
BRD-K15273135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30232
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	4.1776
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04897
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of protein secretion	GO Biological Process Annotations 2015	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.53596
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A75087829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05009
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859237
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	128.628
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89097
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15526
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895242
COR-L311	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF516	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30592
Neuronal System	Reactome Pathways 2014	1.0	null
TEDISAMIL	DGIdb Drug Targets 2026	1.0	0.22055
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51874
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97964
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43687
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050999
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10603
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901598
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11964
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13924
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7846764-41598_2021_81773_MOESM3_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.60322
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39924
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36763492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71102
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23235
brain	GTEx Tissue Gene Expression Profiles	1.0	0.962581
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15757
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0052
regulation of establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39643
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1474
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409731
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03795
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11268
OVKATE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63537
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06701
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
cellular potassium ion transport	GO Biological Process Annotations 2015	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.25974
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926901
BRD-K73849129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75213
GTEX-OOBK-2025-SM-3LK5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922232
voltage-gated potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1031
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30558
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.081219
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01677
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3431-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64531971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84158
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02991
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4204
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.33938
PHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28471
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4553
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.0875
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
abnormal neuron morphology	GWASdb SNP-Phenotype Associations	1.0	1.38847
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11386
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3538
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81884775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69127
BRD-K52152765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05629
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17224
BRD-K70302892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87282
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38107
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22903
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19164
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.57058
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02334
protein complex	GO Cellular Component Annotations 2015	1.0	null
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24013
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38776
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34697
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.61138
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14081
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17925
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68856
SARS-CoV MA15_Day2-C57BL6_None_GSE50878	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.48772
TIG3TD	CCLE Cell Line Gene Expression Profiles	1.0	1.45071
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19081
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82601
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36567
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.13164
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052102
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.683
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865099
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849823
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.49479
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59815
establishment of localization	GO Biological Process Annotations 2015	1.0	null
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04491
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04565
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64419
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67536
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94745
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87372
protein oligomerization	GO Biological Process Annotations 2015	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854746
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14255
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8951
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4543
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
HDLM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93792
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42457
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-A90969585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29854
BRD-K19084671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12105
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58121
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.146094
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86204
Perturb_9067_OE_LCN2_SRP193321	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43312
Perturb_8060_KO_TP53_SRP182675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.61521
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53945
regulation of heart contraction	GO Biological Process Annotations 2015	1.0	null
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39429
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857085
layer 3 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16871
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48312
BRD-K62288678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16359
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16461
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77935
CDX2_01_357	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.18563
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20345
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27864
BRD-K67508052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30274
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29917
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915548
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59338
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6394
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57965
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08478
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K87808996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2452
decreased circulating serum albumin level	IMPC Knockout Mouse Phenotypes	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02764
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0867
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
potassium ion transport	GO Biological Process Annotations 2023	1.0	null
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09793
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37019
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50826
BRD-K47541706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09732
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46524
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074223
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865285
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49545
CRCGN015_HEPG2_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07585
Lung adenocarcinoma_LUAD_TCGA-44-3396-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Potassium Channels	Reactome Pathways 2024	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41818
BRD-K14121002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79262
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.74442
GSE126402_1_v_3_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7048
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08716
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77526
generation of precursor metabolites and energy	GO Biological Process Annotations 2015	1.0	null
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93269
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_214_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30982
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04093
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4846
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.36874
GSE210101,GSE210114_1_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24591
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40767
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8229
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053961
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
FAM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07123
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01199
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF528	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74946
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14836
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08389897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39938
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3PZ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Banded collagen fibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37646
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.95246
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939942
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.753
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4728
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03874
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41823
channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
KMBC2	DepMap CRISPR Gene Dependency	1.0	2.95901
PMC12502296-40246_2025_829_MOESM3_ESM.xlsx-Supplementary_Table_6-Supplementary_Table_6_Significant_eQTLs_MR_results_between_the_expression_of_druggable_genes_and_NSCLC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.13212
single-organism localization	GO Biological Process Annotations 2015	1.0	null
BRD-K39672303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41745
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0658
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64766
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932446
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34519
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02404
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04187
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.570021
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65974
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	12.1205
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76026
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871286
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.887922
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99384
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06768
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-7085-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.990183
Potassium channel tetramerisation-type BTB domain	InterPro Predicted Protein Domain Annotations	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10006
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
HNF4alpha_DEPLETION_GDS4798_91_human_HepG2 hepatocellular carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9527
BRD-K67137502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12572
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42223
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.06688
BRD-K46126513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6774
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.71142
potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09686
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.581
PRKACB	Pathway Commons Protein-Protein Interactions	1.0	null
motor neuron atrophy	GWASdb SNP-Phenotype Associations	1.0	1.38847
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76873
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23285
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K77603027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6989
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K68078571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46645
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03554
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39935
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47592
LIVF001-018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0721
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11935
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21597
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
ethanol_homo sapiens_gpl96_gds2767	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23541
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067629
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C7-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9382
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44961
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74203
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57827
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38251
NUDT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06584
Acute Myeloid Leukemia_LAML_TCGA-AB-2994-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of blood circulation	GO Biological Process Annotations 2023	1.0	null
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.41905
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87706
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043975
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Cocaine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.559
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79658
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10273
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8958
CDKN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18954
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.954393
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79651
PMC11666716-41698_2024_782_MOESM1_ESM.pdf-2-PRDM10_PRDM10	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05018
liminal part of alar r1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53909
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10261
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.100779
BRD-K63579322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19753
BRD-K87092114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15153
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PC3	CCLE Cell Line Gene Expression Profiles	1.0	1.47918
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841856
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35048
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83115435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72939
regulation of heart contraction	GO Biological Process Annotations 2023	1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
voltage-gated potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Familial adult myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88241
Sick sinus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
Lung adenocarcinoma_LUAD_TCGA-95-7039-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOXL2_DEPLETION_GDS4884_88_human_MDA-MB-231 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09929
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85263
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10447
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870426
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78587
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93715
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5214
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55951
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13971
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17294
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.36874
THAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70126
Pulmonary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92339
ONS-76	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59727
Voltage-dependent channel, four helix bundle domain	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83345
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.37846
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CRCGN011_HEPG2_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19185
BRD-K41410736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44591
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Human - Motor Cortex - Cluster - THEMIS+ SLC22A18+ Layer 5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050853
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	187.619
BRD-K45471346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63351
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62592
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05381
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	1.0	1.34704
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5719
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2963
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12164
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824199
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05688
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K30252238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00138
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9194
regulation of hormone secretion	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871958
OVCA420	DepMap CRISPR Gene Dependency	1.0	4.92953
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.126
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
POGLUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80027
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86913
Perturb_15795_KO_Junb_SRP234700	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.27778
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03284
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
BRD-K88437756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16284
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.096
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30566
GSE89767_4_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42879
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09325
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16577
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53113
delayed rectifier potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853617
THOC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00538
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32475
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070411
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8576
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2999
GA10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44757
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11415
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.887922
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93954
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16345
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86105
transport	GO Biological Process Annotations 2015	1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11596
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2835
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844761
BRD-K30117087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3176
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86992
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054285
BRD-K83276573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17187
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4740-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A83P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42776812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65051
substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.585108
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19225
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80941
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10677
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854417
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23443
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78113
BRD-K42435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03527
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900029
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05182
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
voltage-gated potassium channel complex	GO Cellular Component Annotations 2023	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4455
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79051
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983316
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68295
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.59809
OVCAR-3	GDSC Cell Line Gene Expression Profiles	1.0	1.44111
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956557
JHOS4	CCLE Cell Line Gene Expression Profiles	1.0	1.91207
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03386
HNF4A_KD_GDS4798_550_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
T24	BioGPS Cell Line Gene Expression Profiles	1.0	0.893396
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66434
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-105-GATA6_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.13271
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.274453
Opioid abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.036
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10337
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64765
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42336
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71156
GOPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7943
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61263
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27519
KANSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01482
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38302
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958016
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56153
BRD-K54467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02884
SLR25	CCLE Cell Line Gene Expression Profiles	1.0	1.49831
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20688
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1476
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831601
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317679
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17618
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8393
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76026
BRD-K80893668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09957
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12041
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4929
BRD-K12613826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59935
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872586
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91512
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10239
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17392
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
BUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95555
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36702
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845587
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076876
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52736
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11525
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946929
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23083
GSE143847_2_v_0_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055173
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893313
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24109044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44449
BRD-K42757676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74442
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860895
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11337
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872102
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.994638
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05098
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
JHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13551
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37649
GSE168676_0_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87212
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20239
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.63611
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64307
transporter complex	GO Cellular Component Annotations 2015	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08408
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30397
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04346
Sarcoma_SARC_TCGA-3B-A9HO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3892
vesicle	GO Cellular Component Annotations 2015	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50068274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07723
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05902
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90103
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11525
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929426
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085231
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04911
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05396
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50512
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09606
regulation of localization	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14498
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841272
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21795
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51483
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57117
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
BRD-K06846146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10259
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12552
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16348
BRD-K54317642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17598
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.5684
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29039
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.6025
Rectum adenocarcinoma_READ_TCGA-DY-A1DC-01A-31R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.176942
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28694
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067798
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55577
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-806-JRK_JRK	Rummagene Transcription Factor Associations 2026	1.0	null
decreased cardiac stroke volume	IMPC Knockout Mouse Phenotypes	1.0	null
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35575
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96395
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16386
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923882
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.82601
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56663
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45943
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F2-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49362
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	1.53963
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18948
BRD-K12384030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47943
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.753
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Reactome Pathways 2024	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0578
BRD-K55478267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30686
PMC12549544-mmc2.xlsx-AA_D21_VS_D28-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90541
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46298
BRD-K70969650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37906
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.07269
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867097
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.536441
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2723
BRD-K14251637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.21998
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067036
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37854
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7197
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33235
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.953981
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18159
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23377
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933859
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35381
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17385
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14653
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.127918
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83513
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5264
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4045
16498405-TableS3	GeneSigDB Published Gene Signatures	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.969
GTEX-S33H-1226-SM-4AD69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00187
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6631
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.173
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1316
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968323
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14968
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98479
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78441
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0142
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0264
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864114
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00462
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60559
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17633
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22407
BRD-K62312047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11216
metal ion transport	GO Biological Process Annotations 2015	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994634
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57901
cation channel complex	GO Cellular Component Annotations 2015	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21161
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3777
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.839613
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05098
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915548
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7969
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14419
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4847
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25174
substance dependence	GWASdb SNP-Disease Associations	1.0	0.399703
DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells -  7 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K06537903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34241
BRD-K36002293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04851
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
Colon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZDHHC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13944
BRD-K99078335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22774
Perturb_228_KO_Lmx1b_SRP194283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.79646
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992222
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53744
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38999
MKN74	DepMap CRISPR Gene Dependency	1.0	2.10907
BRD-K66479240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23695
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934806
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
BRD-K67353973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19828
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22965
BRD-K47175449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00537
SF172	CCLE Cell Line Gene Expression Profiles	1.0	2.82477
GTEX-TKQ1-1226-SM-4GICJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.11634
BRD-K61059900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06559
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90221
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.51283
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857255
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25451
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076553
CORL95	CCLE Cell Line Gene CNV Profiles	1.0	2.08196
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26954
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87366
rostral interstitial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20503
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.57026
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05784
potassium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20854
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15434
ATF6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92927
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00924
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05378
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21789
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18028
BRD-K78603273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69985
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51323
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27019
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1476
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58891
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16516
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28978
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30529
hydroxytoluic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16802
NCIH69	CCLE Cell Line Gene CNV Profiles	1.0	2.00933
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.57058
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53701
abnormal internal genitalia	GWASdb SNP-Phenotype Associations	1.0	0.123873
Familial febrile seizures	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67039
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.75631
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78154
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0775
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21963
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
r1 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35669
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02515
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_150_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42206
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PK1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53869
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65974
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981067
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.826885
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.755726
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	1.41596
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57594
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01046
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859005
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.002974
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66705
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49855
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45785
ethotoin-2196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62946
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.17566
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11052
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.21959
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11455_KD_GPRC5C_ERP135375	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.12269
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97803
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23033
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9874
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32049721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22673
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54859
Sarcoglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.906
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2667
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054303
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
RPRML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50076
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2657
SOCS3_KO_GDS3149_297_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49529
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.93774
Perturb_13785_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.77901
BRD-K31778735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28957
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37194
HCC364	CCLE Cell Line Gene Expression Profiles	1.0	1.40383
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8532
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11533
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.04937
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104366
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53604
H3K9me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44125
regulation of peptide secretion	GO Biological Process Annotations 2015	1.0	null
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13196
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65094
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52553
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23046
Perturb_9760_KO_Ctcf_SRP273104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.6144
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18159
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958689
BRD-K77108448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3838
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02869
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87974
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CBX2	ENCODE Transcription Factor Targets	1.0	null
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72719
stomach	HPA Tissue Protein Expression Profiles	1.0	1.57058
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33491
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15827
meta1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
GOLPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03907
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1488
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3608
BRD-K38403252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64288
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162688_3_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ED-02-CL76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201836
YH-13	GDSC Cell Line Gene Expression Profiles	1.0	2.15594
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04845
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27092
Cannabis dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
BRD-K02420839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47502
BRD-K92498491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05842
BRD-K54549319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5752
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00665
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.865099
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22796
BRD-K91361836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53842
BTB/POZ-like	InterPro Predicted Protein Domain Annotations	1.0	null
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25572
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.17596
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5381
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1423
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2267
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971878
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64992851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01438
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.15547
CRCGN014_HEPG2_3H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00357
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4549
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07823
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.581
Voltage gated Potassium channels	Reactome Pathways 2024	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051317
PAX2_01_72	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59768
CRCGN015_MCF10A.TP53.M_24H:I05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40808
MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52712
NERISPIRDINE	DGIdb Drug Targets 2026	1.0	0.17644
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.722809
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
regulation of peptide hormone secretion	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933266
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8531
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53875
SLC2A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35595
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1476
Acute Myeloid Leukemia_LAML_TCGA-AB-2841-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969178
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38416
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34743
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0065
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24549
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29039
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58301
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17962
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039251
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC7203476-Table_3.XLSX-Sheet1-MI_MII_overlap_99_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917582
nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.043246
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052581
BRD-K87418410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74549
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9758
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80259
BRD-K16673836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03731
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	1.25353
GTEX-S4Z8-1726-SM-3K2AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14898
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36151
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07117
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968959
Lung squamous cell carcinoma_LUSC_TCGA-85-A50M-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28724
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09091
BRD-K96431636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46496
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03604
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2886
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.598696
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060943
SYNGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28487
Mucolipidosis type IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07008
Perturb_3061_KO_Fgf21/Clpp_SRP357955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03006
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.1016
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073993
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19507
BRD-K47947160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51742
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85484
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18225
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23645
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15206
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04684
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42624
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54171
SW954	GDSC Cell Line Gene Expression Profiles	1.0	1.61153
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75219
HINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69474
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
localization	GO Biological Process Annotations 2015	1.0	null
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.49856
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9835
BRD-K05154886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82314
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051923
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1828
PMC5495879__F3	PFOCR Pathway Figure Associations 2024	1.0	null
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90048
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13318
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32228
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40834
CYLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.0666
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.52971
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05956
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34590335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3934
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6_01_85	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60592
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47267
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10809
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884457
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04139
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96263
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998733
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74478
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7785
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
voltage-gated potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853458
TBC1D3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55917
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54699
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886413
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
OVISE	CCLE Cell Line Gene Expression Profiles	1.0	1.93733
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03346
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40186
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13897
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21955
CAMA1	DepMap CRISPR Gene Dependency	1.0	2.80171
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890211
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76384
Lung squamous cell carcinoma_LUSC_TCGA-22-1017-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78825
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96706
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20479
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84716
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12802
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193348
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
PMC10087102-LSA-2023-02054_TableS5.xlsx-Sheet_1_-_Supplementary_Table_6-Supplementary_Table_6_PITA_filtered_output_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06701
BRD-K76672145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00421
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052083
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28669
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38879
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7081
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6459
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.116
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9592
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74586
cellular_component	GO Cellular Component Annotations 2015	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.14261
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31441930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51604
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10994
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6780_KD_MED12_ERP024018	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.94058
membrane part	GO Cellular Component Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00053
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7807
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23705
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	4.06726
increased heart weight	IMPC Knockout Mouse Phenotypes	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.26234
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12347
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
TNFRSF10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87882
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72893
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39939
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052936
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31429
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE98579_0_v_1_tfam_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04303
plicamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20026
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50638
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40097
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82069
atrophy/degeneration affecting the central nervous system	GWASdb SNP-Phenotype Associations	1.0	1.38847
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1667
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.34181
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07261
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979847
PMC12555112-Supplementary_Data.pdf-1-FOXK2_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65601
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04991
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12019
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96527
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52843
PMC4416014-pone.0125585.s010.xls-d_-BNC_network-Interactor_B_BNC1	Rummagene Transcription Factor Associations 2026	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071067
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15697
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2628
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18159
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hyperactivity	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928093
NCIH810	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6685
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59258
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.959915
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
ion channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27622
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61313
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1303
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90308
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.866988
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.581
BRD-K01520647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02603
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
potassium channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7934
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.07804
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18982
Lung squamous cell carcinoma_LUSC_TCGA-70-6722-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3855
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32173
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00979
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.044
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053776
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21811
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58753
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	2.41953
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861016
CRCGN016_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03846
cefmetazole-2524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07174
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1479
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14504
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60628
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86313
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.671
BRD-K65392756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97039
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0593
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874212
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00291
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891746
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26598
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.830412
potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56116
BRD-K05205967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0814
BRD-K71253424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89679
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34011
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03514
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00433
YKG1	DepMap CRISPR Gene Dependency	1.0	2.7005
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988831
HCFC1	ENCODE Transcription Factor Targets	1.0	null
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36173
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30593
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38033
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17573
KPNYS	DepMap CRISPR Gene Dependency	1.0	6.065
LB771-HNC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43091
BRD-K43203897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52432
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15496
BRD-K38120474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03389
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69798
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13644
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0557
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15787
lung disease	GWASdb SNP-Disease Associations	1.0	0.569379
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.966
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066404
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31108
Metabolism	Reactome Pathways 2024	1.0	null
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85663
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04286
CXCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86467
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
SNU46	DepMap CRISPR Gene Dependency	1.0	3.50333
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59094
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7579
C3A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45518
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33649
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11273
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29565
BRD-K13206026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2266
Perturb_13787_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.17876
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33513
BRD-K31644794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1378
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05562
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89001
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43433
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925042
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925629
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.088927
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863469
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124329
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13457
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.90523
BRD-K78120854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09465
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7657
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6606
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985513
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28049
MYOG	ENCODE Transcription Factor Targets	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01839
cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00859
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.440914
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.31613
BRD-K09261031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04833
Migraine with aura	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Arsenic	CTD Gene-Chemical Interactions	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95362
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40382
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09895
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03048
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844519
CRCGN013_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23972
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17193
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846214
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71231
plant vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.665995
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8601
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22903
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63369
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35402
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.861671
regulation of system process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21282
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.48197
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12536
BRD-K31248348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33339
BRD-K89992188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0565
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24261
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
regulation of blood circulation	GO Biological Process Annotations 2015	1.0	null
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2116
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99922
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50978
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.57058
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1356
CRCGN008_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3173
16498405-TableS7	GeneSigDB Published Gene Signatures	1.0	null
Anterior cardinal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.40122
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.99427
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37241
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051146
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.089
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4846
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852892
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10473
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06208
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1524
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
BRD-K80462316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43509
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.23
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15576
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898598
drug dependence	GWASdb SNP-Disease Associations	1.0	1.53704
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
voltage-gated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09466
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0829
BRD-K49577636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03995
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Potassium Channels	Reactome Pathways 2014	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998733
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29144
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057895
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
BRD-K47999752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56203
NCI-H2141	GDSC Cell Line Gene Expression Profiles	1.0	1.53531
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01864
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78368
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048637
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.978687
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.8964
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834087
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.96037
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29743
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10603
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3026
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51851
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10834
HS934T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64059
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Sarcoma_SARC_TCGA-SI-AA8B-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16737
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848274
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1378
GSE183474_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.20892
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.753
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28601
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975737
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22164
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19164
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63648
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847883
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36041
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6861
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29549
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77322
potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
BRD-K52075209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30585
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889425
BRD-K07688551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1131
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96395
BRD-K89514545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08765
CRCGN011_HEPG2_24H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1911
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53443
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BT16	DepMap CRISPR Gene Dependency	1.0	6.1779
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59815
Lung adenocarcinoma_LUAD_TCGA-55-6981-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85702
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.62552
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969506
BRD-K34929471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41944
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03216
SF539	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86205
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79658
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30558
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828562
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0962
BCS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86374
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27695
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65197
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
MM160113	DepMap CRISPR Gene Dependency	1.0	2.26909
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76725
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972593
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28362
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07558
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_1_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of protein transport	GO Biological Process Annotations 2015	1.0	null
CRCGN011_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01035
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40281
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947963
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923178
Potassium channel	InterPro Predicted Protein Domain Annotations	1.0	null
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03903
Neonatal abstinence syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
BRD-K25185158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40386
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20554
Urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4102
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23723
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52272
Perturb_4707_KD_Dnmt3a_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.28616
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43869
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876142
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K71893034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25575
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07765
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24431
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50645
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0672
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.59632
Smoking status (ever vs never smokers)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21798
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29412
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120795
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64883
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37922
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15926
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75474
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.09139
GSE126402_1_v_0_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827015
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09836
NCIH1092	DepMap CRISPR Gene Dependency	1.0	2.4009
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4366
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58215
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37563
Age at first sexual intercourse	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.53979
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00495
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829689
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K89014570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44563
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3431
umbilical vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182969
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
RERF-LC-MS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.356
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063716
Perturb_7058_KO_Sod2/Ogg1_ERP107154	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.58167
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77023196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71338
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874279
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DALFAMPRIDINE	DGIdb Drug Targets 2026	1.0	0.2005
Regulation of insulin secretion	Reactome Pathways 2014	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65839
BRD-K36347292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15142
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23402
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987588
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14656
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24708
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826111
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12317
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.536241
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50043
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00665
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.68901
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46065
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877997
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
Psoas major	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78471
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12733
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08601
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.208
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03372
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.163439
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068169
Severe insulin-resistant type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53652
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06261202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26122
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890445
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841984
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00692
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0546
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.401
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00606
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90255
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79237
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29365
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K47690679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5283
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844296
potassium channel complex	GO Cellular Component Annotations 2023	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19275
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069042
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835116
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.59925
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13708
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41662
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91915
SOCS3_KO_GDS3149_8_mouse_multiple cell types	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53383
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
Potassium channel, voltage dependent, Kv	InterPro Predicted Protein Domain Annotations	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30068
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9856
GSE202470_1_v_3_stat6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POTEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19958
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225622
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20535
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853459
increased heart weight	MGI Mouse Phenotype Associations 2023	1.0	null
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59919062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68406
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62515
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10651
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86204
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.581
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66915
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20466
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91072
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36645
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92054
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19156
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5878
Opioid sensitivity	GWAS Catalog SNP-Phenotype Associations	1.0	0.552116
BRD-K96505704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16759
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20479
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.72864
voltage-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Opiate dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
glioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290295
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61325
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29481
BRD-K43653210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0014
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936107
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63233
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05478
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99898
BRD-K54505405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00056
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16337
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
Urinary bladder smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Metabolism	Reactome Pathways 2014	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.133
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8055
BRD-K52157065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47884
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40873
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11236317-aging-16-205930-s001.pdf-0-CREB3L3_CREB3L3	Rummagene Transcription Factor Associations 2026	1.0	null
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00604
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39609
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
IRF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0759
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872304
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91424
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09742
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57334
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AMIFAMPRIDINE	DGIdb Drug Targets 2026	1.0	0.210048
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982713
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928792
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53624
ion transport	GO Biological Process Annotations 2015	1.0	null
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57416
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880289
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34879
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05682
GSE137144_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54505
BRD-K33961669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10548
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061417
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14094
BRD-K74927219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00871
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11994
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32986
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K64698045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10938
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85765
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03683
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1468
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25874
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965199
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47578
Enterovirus 71_4Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.28153
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42963
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0664
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5972
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
GMS-10	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72232
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35517
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
CRCGN011_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92715
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.598696
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1476
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60822
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.955093
Perturb_12868_KD_EP400_SRP059494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55456
abnormal motor neuron morphology	GWASdb SNP-Phenotype Associations	1.0	1.38847
abnormality of the female genitalia	GWASdb SNP-Phenotype Associations	1.0	0.133596
BRD-K55766625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87041
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053881
chr18_79899561_G_T_b38	GTEx eQTL 2025	1.0	2.02899
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2658
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21104
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905223
BRD-K43495666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57349
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858627
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05943
TTC642	DepMap CRISPR Gene Dependency	1.0	4.25322
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25883
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45763
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03781
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511778
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LB996-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-2.41175
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09686
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00432
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939118
PEO4	DepMap CRISPR Gene Dependency	1.0	3.49735
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11564
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49425
BRD-K59913416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91736
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03246
BRD-K77082178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46165
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K68731395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29414
Endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12477
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28679
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0889
Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.42273
BRD-K50162138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02894
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53877
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079953
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10798
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
umbilical vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196803
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877864
Voltage gated Potassium channels	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07643
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6259
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44574
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26338
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.514
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047707
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937978
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02649
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased cardiac muscle contractility	MGI Mouse Phenotype Associations 2023	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71368
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34945
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909311
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28929
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3447
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842734
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92069
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01672
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25584
GUANIDINE HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.22055
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857291
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40958
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.77006
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05822
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CORL47	CCLE Cell Line Gene CNV Profiles	1.0	1.35571
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0159
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23409
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01892
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32505
abnormal genital system morphology	GWASdb SNP-Phenotype Associations	1.0	0.085978
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31352
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51108
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K21910317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11529
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33817
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09937
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89014
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9759_KO_CTCF_SRP102228	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911906
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53912
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00205
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32611
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K37253987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20796
BRD-K54554531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31198
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833765
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25707
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3184
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31884664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21671
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37639
Perturb_3213_KO_Ifnar1_ERP120506	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79523
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833307
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	2.68437
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09076
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46373
GTEX-Q2AG-1226-SM-4GICA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905238
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.860115
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41367
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18082
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27637
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86937728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20806
GSE79291_1_v_0_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60193
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25584
BRD-K13672060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00332
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14708
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	DepMap CRISPR Gene Dependency	1.0	8.02595
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78916
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.878
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.549212
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831706
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06165
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01047
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.384
regulation of transport	GO Biological Process Annotations 2015	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	7.107
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034508
myclobutanil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06311
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054897
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931136
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.35992
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1393
SCLY	ChEA Transcription Factor Targets	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83694
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64351
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90116
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02374
BRD-K79627231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.25753
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.50001
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75274
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22718
BRD-K72519622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07082
CRCGN015_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2554
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.936
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67228
TN2	DepMap CRISPR Gene Dependency	1.0	3.41863
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949924
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97198
BRD-K58863194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04046
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93336
BRD-K66032509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14902
F5	CCLE Cell Line Gene Expression Profiles	1.0	1.7411
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842791
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039991
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0355
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40097
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161753
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6355
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6069
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2117
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23917
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55511
BRD-K68916730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86995
BRD-K41009039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41679
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90279
long qt syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.71078
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53742
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.19509
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9273
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59348
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4492
Hyperplasia	CTD Gene-Disease Associations	1.0	1.02821
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48367
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76995
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059264
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076876
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5605
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27846
BRD-K07020302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62767
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61157
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20854
BRD-K32511780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66366
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18159
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05458
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23761
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869613
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28233
BRD-K36393312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36352