association	dataset	threshold value	standardized value
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.234191
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835637
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
delayed rectifier potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09074
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.447524
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A264-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846598
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.37028
infratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077751
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carbamazepine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0330539
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04717
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15889
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10299
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22474
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kcnh5	GeneRIF Biological Term Annotations	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
blepharophimosis-impaired intellectual development syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4807
abnormal fear/anxiety-related behavior	MPO Gene-Phenotype Associations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25504
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78439
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.141619
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22948
overnutrition	GWASdb SNP-Disease Associations	1.0	0.484681
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2064
Liver Diseases	CTD Gene-Disease Associations	1.0	1.52914
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.07511
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02716
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.49334
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2512
Integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
S-Adenosyl-L-methionine (disulfate tosylate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0190744
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
glycine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052226
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.249
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67392
SUZ12	ChEA Transcription Factor Targets	1.0	null
methylcrotonoyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
Medulloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.623
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13878
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852727
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
Intestinal Neoplasms	CTD Gene-Disease Associations	1.0	1.07983
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3926
NCIH2172	CCLE Cell Line Gene Expression Profiles	1.0	1.67561
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
domains	GeneRIF Biological Term Annotations	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Chodhfr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67911
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
Kna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6029
Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB13	DepMap CRISPR Gene Dependency	1.0	4.08283
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00049
non-small cell lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.349717
K562_Quercetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143735
schizophrenia	GAD Gene-Disease Associations	1.0	null
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.102206
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1411
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1304	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Gastric corpus mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
eomes_23431145_e14dot5_neocortex_lof_mouse_gpl6246_gse43387	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.06135
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
K562_WP1066_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164915
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889663
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
performed	GeneRIF Biological Term Annotations	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02217
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TEDISAMIL	DGIdb Drug Targets 2026	1.0	0.165412
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5702
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38602
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.819
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03526
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01505
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050437
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32543
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4747
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4499
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07367
true	GeneRIF Biological Term Annotations	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE6	CCLE Cell Line Gene CNV Profiles	1.0	2.09655
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
structural	GeneRIF Biological Term Annotations	1.0	null
NRF2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069559
kidney disease	GWASdb SNP-Disease Associations	1.0	1.14065
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_immune_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_3_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058867
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957742
hsa-miR-217	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.6505
interleukin-23 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7061
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.932557
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96947
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933602
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	1.63405
hsa-miR-1256	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02148
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05219
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
EZH2	ENCODE Transcription Factor Targets	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.067225
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39528
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7906
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22015
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955192
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8239
Perturb_12868_KD_EP400_SRP059494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982773
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
layer II of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886314
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AMIFAMPRIDINE	DGIdb Drug Targets 2026	1.0	0.157536
peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Doxorubicin (hydrochloride)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0218782
TIA1_KO_GSE54418_266_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70335
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.987958
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35912
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4103
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11525
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
cell surface	GO Cellular Component Annotations 2015	1.0	null
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2025	1.0	null
Indacaterol (maleate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.025053
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18054
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.84055
Infancy electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19481
potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14279
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955438
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28308
Pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oligomers	GeneRIF Biological Term Annotations	1.0	null
cyclic	GeneRIF Biological Term Annotations	1.0	null
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.79082
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09482
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50027
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00785
TIA1_KO_GSE54418_265_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
exome	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912047
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407453
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_3_AP1_Up_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.677395
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.94872
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.054396
PCI-15A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
structure	GeneRIF Biological Term Annotations	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33626
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44532
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64859
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.861455
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.788
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47148
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.874612
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912855
potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33243
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Vitamin K4_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0235479
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926174
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03355
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73868
GATA2	ENCODE Transcription Factor Targets	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23197
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249302
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55189
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075613
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839097
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883741
whole	GeneRIF Biological Term Annotations	1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03371
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7268
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYSE-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.811
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.944891
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956139
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15659
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.321181
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05173
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05062
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.09075
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101529
Plastid nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9997
K562_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0275317
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847284
Adult Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04538
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.33451
K562_Ki16425_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250535
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.547
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35198
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36812
Clark-Baraitser syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
represent	GeneRIF Biological Term Annotations	1.0	null
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889591
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045835
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.18456
Episodic ataxia type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.21981
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09768
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB3A_KO_GDS2483_701_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058804
TRIM24_Deficiency_GDS3087_609_mouse_Hepatocellular carcinoma (HCC) tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63247
RmlC-like jelly roll fold	InterPro Predicted Protein Domain Annotations	1.0	null
Perturb_4180_KO_Tsc1_SRP279018	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45019
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-147	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21687
Autosomal recessive nonsyndromic deafness 94	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93854
mood disorder	GWASdb SNP-Disease Associations	1.0	0.372858
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11286
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35126
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08112
Perturb_10359_KD_Ascl1_SRP340223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.2218
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72463
protein kinase activity	GO Molecular Function Annotations 2015	1.0	null
Epilepsy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.39387
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939721
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
voltage-gated monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906181
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981408
hsa-miR-3673	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62551
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
K562_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019318
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830743
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02175
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02265
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903692
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3945
HSF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17046
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16465
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16711
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09188
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17812
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.710719
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytarabine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0291893
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-595	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3041
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7032
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78918
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4844
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1478
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10558
propose	GeneRIF Biological Term Annotations	1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0294
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4758
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374068
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14982
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.126165
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.931861
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867841
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13178
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58895
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71862
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56443
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041556
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.141888
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50648
CDAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39501
GK_KO_GDS1555_127_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
increased thigmotaxis	MPO Gene-Phenotype Associations	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN3_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
K562_JNJ-26854165_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150785
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17968
Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
Visual areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02835
Ion transport domain	InterPro Predicted Protein Domain Annotations	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49909
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064457
HCC1187	CCLE Cell Line Gene Expression Profiles	1.0	1.45442
K562_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217128
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15328
MEF2A_KD_GDS4759_340_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32027
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
voltage-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566828
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986515
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397979
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00805
Minodronic acid_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00986549
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.948359
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
K562_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211324
Hyperplasia	CTD Gene-Disease Associations	1.0	1.59778
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227707
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05939
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0225
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.98029
Perturb_10411_KD_MAP3K7/CHD1_SRP310151	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.20734
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
Body Mass Index Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21223
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27803
SW1463	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.760576
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12921
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642048
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.93551
AMIFAMPRIDINE PHOSPHATE	DGIdb Drug Targets 2026	1.0	0.165412
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889228
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0458
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06727
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73937
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4713
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00806
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17935
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09322
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24831
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.03671
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06523
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.904788
outer CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97974
EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8482521-mmc13.xlsx-Phosphosites_12_hr_48_hr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4796-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102876
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86822
residue	GeneRIF Biological Term Annotations	1.0	null
COLO800	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075068
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847776
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868126
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14982
Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28041
placenta	HPA Tissue Gene Expression Profiles	1.0	0.969046
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15154
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06763
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.55108
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.073752
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
interacting	GeneRIF Biological Term Annotations	1.0	null
Autosomal dominant intellectual developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73649
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063981
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895553
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.722633
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00844
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endometriosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.82
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063593
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.05384
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.781
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	155.998
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YAP1	ChEA Transcription Factor Targets	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.629101
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09663
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18136
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2258
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921843
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29985
REST	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10330983-ab-22-0432-Supplementary-Table-8.pdf-47-INTS1_MAFK_MAFK	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88724
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	1.79236
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09001
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GS-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.53941
Early infantile epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409351
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01618
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14725
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.233
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38815
threedimensional	GeneRIF Biological Term Annotations	1.0	null
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49422
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0729
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
abnormality of connective tissue	GWASdb SNP-Phenotype Associations	1.0	0.413807
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44081
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11286
SF172	CCLE Cell Line Gene CNV Profiles	1.0	1.64168
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10384
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
electron	GeneRIF Biological Term Annotations	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74845
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1974
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43243
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
resistin	GAD Gene-Disease Associations	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15003
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16607
humans	GeneRIF Biological Term Annotations	1.0	null
PAS domain	InterPro Predicted Protein Domain Annotations	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04262
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15085
cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169571
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.38822
pancreatic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288158
novo	GeneRIF Biological Term Annotations	1.0	null
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05353
SKES1	CCLE Cell Line Gene Expression Profiles	1.0	1.76208
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05283
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851578
K562_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191391
maximal midexpiratory flow rate	GAD Gene-Disease Associations	1.0	null
Dorsal hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26058
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46089
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844733
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00987
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57469
UBL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15296
adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.253479
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943109
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.867868
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
critical	GeneRIF Biological Term Annotations	1.0	null
epilepsies	GeneRIF Biological Term Annotations	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979452
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.597
AKT1_OE_GDS2308_498_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
BI-3406_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0187916
Atazanavir (sulfate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0195646
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7623
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939381
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.808
myocardial infarction	GWASdb SNP-Disease Associations	1.0	1.24623
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87713
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CGTHW1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47469
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13685
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.67484
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971041
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975952
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ion	GeneRIF Biological Term Annotations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22496
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14013
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
5-Azacytidine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0221806
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
phosphotransferase activity, alcohol group as acceptor	GO Molecular Function Annotations 2015	1.0	null
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38785
TE10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54889
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65074
Pyridoxine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0237969
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22999
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20522
stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134445
stroke	GWASdb SNP-Phenotype Associations	1.0	0.433364
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65339
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04335
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_9_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42673
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24551
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19506
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.37958
regulation of cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.82
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87435
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.371
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26478
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9233
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58877
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64382
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Developmental and epileptic encephalopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
SCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6778
LK2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00459
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923537
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60387
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6548
PMC5503627-oncotarget-08-39497-s003.xlsx-hyper_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.274
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Maximal Midexpiratory Flow Rate	dbGAP Gene-Trait Associations	1.0	0.705778
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8442
melanoma	GeneRIF Biological Term Annotations	1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49508
time	GeneRIF Biological Term Annotations	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
K562_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019116
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161929
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41252
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34782
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.962111
FAM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47949
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
Darolutamide_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00911362
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.455529
igr1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15268
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Hypertension	CTD Gene-Disease Associations	1.0	1.09366
RBBP5	ENCODE Transcription Factor Targets	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223486
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations	1.0	0.266721
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.244
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77435
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.847976
Filgotinib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0146264
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.83442
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8298
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06616
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21112
USF2	ENCODE Transcription Factor Targets	1.0	null
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65895
Glucose	dbGAP Gene-Trait Associations	1.0	0.716267
Intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cotinine glucuronidation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01914
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899224
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.504
single-organism process	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869706
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.82683
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826996
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5581
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11519
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869561
single-organism localization	GO Biological Process Annotations 2015	1.0	null
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12597
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.23112
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17294
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H19_DEPLETION_GDS4787_92_mouse_C2C12 myoblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.710719
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.710719
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5112
NRF1	JASPAR Predicted Transcription Factor Targets	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
regulation of cell cycle G2/M phase transition	GO Biological Process Annotations 2023	1.0	null
increased anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
RAJI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912855
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Rifaximin_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0221368
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03497
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05781
mRNA_FOXJ2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
arhgef15	GeneRIF Biological Term Annotations	1.0	null
capan-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635976
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.16236
hypomethylation	GeneRIF Biological Term Annotations	1.0	null
Voltage gated Potassium channels	Reactome Pathways 2014	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.945755
SUPM2	DepMap CRISPR Gene Dependency	1.0	2.00024
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
regulation of G2/M transition of mitotic cell cycle	GO Biological Process Annotations 2023	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-292-OTX2_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	GO Cellular Component Annotations 2015	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.32568
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12222
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69311
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04092
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23959
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67381
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
E2F6	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42289
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912047
IRF1	ENCODE Transcription Factor Targets	1.0	null
channel	GeneRIF Biological Term Annotations	1.0	null
voltage-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08477
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16498
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.195774
mRNA_AES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
abnormal startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29317
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984641
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45969
Intelligence	DisGeNET Gene-Phenotype Associations	1.0	null
neuroectodermal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201635
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17983
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27294
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10515
cellular_component	GO Cellular Component Annotations 2015	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.1243
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54259
Larval brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5165
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131935
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37324
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48826
Peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15583
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86415
particle	GeneRIF Biological Term Annotations	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70164
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_2_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10595
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.332291
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
perantsim	GeneRIF Biological Term Annotations	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
roles	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12815
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32485
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1045
Hemorrhage	CTD Gene-Disease Associations	1.0	1.165
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.11902
AKT1_knockdown_141_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.34733
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71265
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01959
EP300	ENCODE Transcription Factor Targets	1.0	null
hela	HPA Cell Line Gene Expression Profiles	1.0	0.904794
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36921
DEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57093
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08997
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.710719
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0548
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.63949
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE138228,GSE138230_2_v_1_cdkn1c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
metal ion transport	GO Biological Process Annotations 2025	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133615
disease	GWASdb SNP-Disease Associations	1.0	0.060968
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28679
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1713
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.979087
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12535
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77011
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29383
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62047
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
kinase activity	GO Molecular Function Annotations 2015	1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
DALFAMPRIDINE	DGIdb Drug Targets 2026	1.0	0.150375
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30357
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092771
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27709
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2854
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16125
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.5276
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.067694
RVH-421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
voltage-gated cation channel activity	GO Molecular Function Annotations 2015	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02913
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7968
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.32726
TP53	ChEA Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22232
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
previously	GeneRIF Biological Term Annotations	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24668
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28598
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.59623
potassium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32235
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071225
quinidine	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.6021
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32516
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.248834
SOX2-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
APOBEC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62161
Potassium voltage-gated channel subfamily H member 5	InterPro Predicted Protein Domain Annotations	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14733
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35936
voltage-gated potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.05461
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
M07E	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45403
metabolic process	GO Biological Process Annotations 2015	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072044
OVMIU	DepMap CRISPR Gene Dependency	1.0	10.0721
Mesopallium ventrale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833061
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreatic ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527928
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01649
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28598
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.75662
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.213564
BCP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39178
central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045545
brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.408666
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848882
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	CCLE Cell Line Gene Expression Profiles	1.0	1.40496
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.121356
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
Dentate granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO684	DepMap CRISPR Gene Dependency	1.0	2.84159
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
NFE2L2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2023	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05456
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09856
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41063
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.41368
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV6_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35129
Lewy body-like hyaline inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26765
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15605
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21708
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14733
GSE232261,GSE232263_0_v_1_usf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN4_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCC9	CCLE Cell Line Gene CNV Profiles	1.0	2.02958
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.50293
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02949
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Major depressive disorder	GWAS Catalog SNP-Phenotype Associations	1.0	0.104568
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Eye-ciliary body	Tabula Sapiens Gene-Cell Associations	1.0	0.0856442
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828241
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.78555
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49748
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24245
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77538
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13154
GB1	CCLE Cell Line Gene Expression Profiles	1.0	1.88331
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064563
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08961
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
NIHOVCAR3	DepMap CRISPR Gene Dependency	1.0	9.24377
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of G2/M transition of mitotic cell cycle	GO Biological Process Annotations 2025	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30962
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32332
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8804
3-methylcrotonyl-CoA carboxylase complex, mitochondrial	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.98029
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33113
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6122
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05631
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23048
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.921
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03491
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59564
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09937
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.869329
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25165
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
panc-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310059
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.13827
NCIH841	CCLE Cell Line Gene Expression Profiles	1.0	2.14451
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.430311
TALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.15256
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS695T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90365
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12366
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0215
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934939
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95412
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23006
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28989
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827118
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893371
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43381
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A253	CCLE Cell Line Gene CNV Profiles	1.0	1.41762
CHK1_KD_GSE54268_666_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal startle reflex	MPO Gene-Phenotype Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of mitotic cell cycle phase transition	GO Biological Process Annotations 2015	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630718
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.484
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32294
chr14_62708242_C_T_b38	GTEx eQTL 2025	1.0	1.40162
POU5F1-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835612
first	GeneRIF Biological Term Annotations	1.0	null
cfpac-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0466
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.505808
Episodic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95695
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21708
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309204
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32446
hsa-miR-648	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hemoglobinopathy	GWASdb SNP-Disease Associations	1.0	0.595123
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885098
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173814
Neuronal System	Reactome Pathways 2014	1.0	null
Dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977034
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09308
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29983
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.31
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.133081
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07271
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31683
regulation of cell cycle g2/m phase transition	GO Biological Process Annotations 2015	1.0	null
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.803
Subcutaneous adipose tissue	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07736
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04602
regulation of g2/m transition of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21708
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5930-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11359
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.183
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.316092
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832814
Potassium Channels	Reactome Pathways 2024	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893495
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	0.710719
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31246
EFNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28435
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02796
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.156783
OC315	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95563
Cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LN319	CCLE Cell Line Gene Expression Profiles	1.0	1.58368
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	2.24324
Perturb_14674_Mut_GCK_SRP089943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.78955
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12517
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
atherosclerosis	GWASdb SNP-Disease Associations	1.0	0.808055
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
Perturb_4186_KO_Abca7_SRP227468	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.62839
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06972
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51811
brain	HPA Tissue Gene Expression Profiles	1.0	1.70997
cellular process	GO Biological Process Annotations 2015	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39507
Intelligence (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978382
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12306
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6624
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42372
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20509
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24236
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10681
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3965
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949612
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829947
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant nocturnal frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
Familial episodic pain syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hereditary sensory and autonomic neuropathy type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C6-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51382
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01076
GSE144484_2_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cation channel complex	GO Cellular Component Annotations 2015	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.710719
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35295
Axonal spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.73413
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Hub Proteins Protein-Protein Interactions	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.908977
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057346
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1373	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75066
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3298
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14303
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.652994
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84969
PMC8482521-mmc13.xlsx-Phosphosites_48vhr_MLR-Gene_names_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057925
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3231
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
Cyclic nucleotide-binding-like	InterPro Predicted Protein Domain Annotations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.82
Harringtonine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0266901
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837134
hsa-miR-1207-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Carotid Artery Diseases	dbGAP Gene-Trait Associations	1.0	0.167555
regulation of transport	GO Biological Process Annotations 2015	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
major depressive disorder	GWASdb SNP-Disease Associations	1.0	1.07599
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73075
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6444
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10054
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98769
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12184404-jitc-13-6-s004.pdf-10-AKAP8L_AKAP8L	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MONOMAC1	DepMap CRISPR Gene Dependency	1.0	2.96152
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE193157_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30039
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861552
K562_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249224
K562_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167811
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3878
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54543
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213410_0_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95137
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.35791
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20422
Glioblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6148
Neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
normocytic anemia	GWASdb SNP-Disease Associations	1.0	0.595123
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSC-19	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE22255_DE-Genes_NOT_Autophagy_NOT_GSE66724_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06331
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880485
Perturb_17326_KO_Dis3_SRP328540	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.30824
K562_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194609
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PANC0403	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39699
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7442
voltage-gated potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.71583
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.73079
hsa-miR-3690	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.46119
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11078
chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.865721
cell part	GO Cellular Component Annotations 2015	1.0	null
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0758
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.710719
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30461
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11046693-pnas.2320938121.sapp.pdf-24-ISL1_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-741-ENSG00000165588_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
mesenchymal stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360782
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.465723
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41812
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.572
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG2	ChEA Transcription Factor Targets	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAOV4	DepMap CRISPR Gene Dependency	1.0	2.55359
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
VMRC-MELG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19741
HUCCT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89885
nucleotide	GeneRIF Biological Term Annotations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0654
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GUANIDINE HYDROCHLORIDE	DGIdb Drug Targets 2026	1.0	0.165412
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28989
cnbd	GeneRIF Biological Term Annotations	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
A2BAR_Deficiency_GDS3662_520_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421529
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43279
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CSE1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05523
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0587
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.297291
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976207
MYC	ENCODE Transcription Factor Targets	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.286
Upper layer 3 cell_Primary visual cortex_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21446
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1485
GSE206400_1_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.75809
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03451
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10718
NCIH1092	DepMap CRISPR Gene Dependency	1.0	5.05676
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nsclc	GeneRIF Biological Term Annotations	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MFE280	DepMap CRISPR Gene Dependency	1.0	7.54409
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21097
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.153818
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4639-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24664
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31644
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169767
protein histidine kinase activity	GO Molecular Function Annotations 2015	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072944
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39527
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67258
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40701
mental depression	GWASdb SNP-Disease Associations	1.0	0.478563
TP53-18474530-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53441
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19652
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0002
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
studied	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863439
NB10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_1_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.302
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24346
Inflammation	CTD Gene-Disease Associations	1.0	1.5992
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11434
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LY97241	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HB-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63247
PMC12211054-spectrum.00100-25-s0002.pdf-56-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Status epilepticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60016
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4171
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0915
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948136
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23399
potassium ion transport	GO Biological Process Annotations 2025	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080198
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32179
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101546_3_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3081
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_UNC0631_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0293304
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.59124
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068278
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE151195_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956139
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89579
QUINIDINE	DGIdb Drug Targets 2026	1.0	0.315071
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064535
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day14-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
sequencing	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27084
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36432
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26548
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1799
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910446
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.86033
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DENND4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96277
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039234
CHD1	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849187
Osteoporosis	dbGAP Gene-Trait Associations	1.0	0.537919
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Long QT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
regulation of cell cycle	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337072
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977937
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08951
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20522
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.493745
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.202746
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.64155
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nematocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
Epirubicin (hydrochloride)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0216722
CHD2	ENCODE Transcription Factor Targets	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14982
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
hsa-miR-1183	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183328
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4488
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-3.01204
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.85934
phosphotransferase activity, nitrogenous group as acceptor	GO Molecular Function Annotations 2015	1.0	null
NKX3-1	JASPAR Predicted Transcription Factor Targets	1.0	null
NRF2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.01966
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345314
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40138
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57571
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bronchus carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913781
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73376
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30146
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042262
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995176
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.879089
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063258
promoter	GeneRIF Biological Term Annotations	1.0	null
Perturb_4211_KO_Fmr1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.83016
Plasma membrane protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34256
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11219
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.99829
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35917
HSC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33054
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475812
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TOV21G	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59168
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Upper layer 2 cell_Primary visual cortex_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	1.09159
PMC3500769-srep00875-s3.xls-CEBP-Time_4_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845785
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.8696
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930072
SNU1079	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62275
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12654
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.68872
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892248
GATA1	JASPAR Predicted Transcription Factor Targets	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
Learning Disorders	CTD Gene-Disease Associations	1.0	1.16203
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.072892
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55127
PCI15A	DepMap CRISPR Gene Dependency	1.0	2.42047
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebellar granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40509
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.126165
transporter complex	GO Cellular Component Annotations 2015	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
K562_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0210395
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40379
SK-MEL-31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Gill raker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	1.55677
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042504
cation transport	GO Biological Process Annotations 2015	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
PMC3500769-srep00875-s3.xls-AP1-Time_24_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63893
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular	GeneRIF Biological Term Annotations	1.0	null
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26058
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cyclic nucleotide-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95343
CAL72	DepMap CRISPR Gene Dependency	1.0	3.09538
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1082
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47332
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9614
OC316	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68271
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH82	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of mitotic cell cycle	GO Biological Process Annotations 2015	1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21112
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084448
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4785
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991168
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00152
vitamin c_mus musculus_gpl6246_gse19377	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34594
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lopinavir_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0230437
SCH	DepMap CRISPR Gene Dependency	1.0	10.6378
hsa-miR-3976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909816
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37168
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41309
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
Paroxysmal extreme pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Neratinib (maleate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0389389
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388535
phosphorylation	GO Biological Process Annotations 2015	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DDX46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14252
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55206
mRNA_STAT3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30285
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pemigatinib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0271066
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4676-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Perturb_7782_KD_ASCC3_SRP023199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.626
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09954
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00699
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
ctermini	GeneRIF Biological Term Annotations	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
mental depression	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.126165
medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.383708
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80125
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942412
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.797144
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961775
Lung squamous cell carcinoma_LUSC_TCGA-22-0940-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sleep duration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SP5_SP5	Rummagene Transcription Factor Associations 2026	1.0	null
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165883
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.9938
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943244
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3066
BL2792 (TRIM24)	NURSA Protein Complexes	1.0	null
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45216
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.764
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal ion transport	GO Biological Process Annotations 2015	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09342
PMC8302638-41467_2021_24677_MOESM4_ESM.xlsx-S1_LMS_SNV-Supplementary_Data_1_Most_Recurrent_Non-Synonymous_Point_Mutations_in_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_233_KD_BRG1_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Roxadustat_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0191446
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512957
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969336
HEY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94869
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853903
NF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10314
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30276
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17202
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17461
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063094
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.06661
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67286
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01932
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912047
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bendamustine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0189245
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424581
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26656
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14139
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Y-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10835
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59837
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ELF1	ChEA Transcription Factor Targets	1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09495
voltage-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Docetaxel_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0306363
Benign familial infantile seizures 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12301
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226667
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71943
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.671285
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3122
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7245
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59155
MOGGUVW	DepMap CRISPR Gene Dependency	1.0	4.71604
bone disease	GWASdb SNP-Disease Associations	1.0	0.132672
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.67914
Integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_1_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32009
Voltage gated Potassium channels	Reactome Pathways 2024	1.0	null
phosphorelay signal transduction system	GO Biological Process Annotations 2015	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091966
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0494
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arbutin_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0160562
KCNH1	Pathway Commons Protein-Protein Interactions	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289569
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36993
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29714
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.233
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39537
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16049
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
microscopy	GeneRIF Biological Term Annotations	1.0	null
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_5472_KD_Ptbp1_SRP265083	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.03771
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26267
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.873938
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
endogenous depression	GWASdb SNP-Disease Associations	1.0	1.07599
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.079
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.018235
SOX2	ChEA Transcription Factor Targets	1.0	null
obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131344
Headache	CTD Gene-Disease Associations	1.0	1.01512
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5622
Subcutaneous adipose tissue	GWAS Catalog SNP-Phenotype Associations	1.0	0.165905
Muscle-mesothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00475801
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.966164
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NFE2L2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3079
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBX3	ChEA Transcription Factor Targets	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3545
placentalspecific	GeneRIF Biological Term Annotations	1.0	null
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.867487
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.01212
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95267
mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.126165
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50049
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
membrane	GO Cellular Component Annotations 2015	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03927
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_3_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Episodic ataxia type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
state	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856721
congenital hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.595123
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057001
form	GeneRIF Biological Term Annotations	1.0	null
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.00862
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98361
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40077
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945442
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36407
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mouse - Motor Cortex - Cross-Species Cluster - Layer 5 glutamatergic neuron, intratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09815
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04529
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20538
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.056126
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55025
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01197
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTEN_KD_GDS4759_337_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC3500769-srep00875-s3.xls-GATA3-Time_1_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07206
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02992
regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
MK-8353_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0173195
PIAS1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8556
closed	GeneRIF Biological Term Annotations	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9057
Hypertrophy	CTD Gene-Disease Associations	1.0	1.32547
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189244
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75824
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96679
NCIH2081	CCLE Cell Line Gene Expression Profiles	1.0	1.97971
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07989
HSC4	CCLE Cell Line Gene CNV Profiles	1.0	2.42996
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74188
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89746
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955438
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Geniculate group, ventral thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06221
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09268
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16419
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39627
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuronal System	Reactome Pathways 2024	1.0	null
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10585
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.0241
CTCF	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
Mesopallium dorsale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
echocardiography	GAD Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	5.95116
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
only	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26677
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834916
LY97241	DGIdb Drug Targets 2026	1.0	3.30825
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.06043
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.59648
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16724
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30111
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1808
noncancerous	GeneRIF Biological Term Annotations	1.0	null
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04241
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874694
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sulfatinib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0315509
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.32785
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00797
binding	GO Molecular Function Annotations 2015	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165624
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.62
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475423
Eye-retinal pigment epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.86514
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6831
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73649
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00797
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08312
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.843984
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.282597
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19429
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05456
Bestatin_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0187352
single organism signaling	GO Biological Process Annotations 2015	1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Plastid chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79743
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.103
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
phosphorelay sensor kinase activity	GO Molecular Function Annotations 2015	1.0	null
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53812
Potassium Channels	Reactome Pathways 2014	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	1.14463
Cyclic AMP	HMDB Metabolites of Enzymes	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.942765
amnion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16643
ASPC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31047
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12817
mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.073
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14093
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.240216
GSE126127_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1255
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937032
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78608
STAT1	ENCODE Transcription Factor Targets	1.0	null
NAMALWA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41403
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06877
GSE206400_1_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pas	GeneRIF Biological Term Annotations	1.0	null
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47136
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0663
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.99667
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
regulation of cell cycle process	GO Biological Process Annotations 2015	1.0	null
ipc298	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.067174
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Spinocerebellar ataxia type 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UT-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GH3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07178
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28614
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883845
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88595
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DAN-G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7037
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.059735
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18207
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.26133
PLB-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HCC2429	DepMap CRISPR Gene Dependency	1.0	2.77202
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16419
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068757
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01109
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24477
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	1.42329
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
potassium ion transport	GO Biological Process Annotations 2023	1.0	null
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48777
CUX1	ENCODE Transcription Factor Targets	1.0	null
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00599
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62451
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
occipital cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00036
K562_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251204
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04159
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60974
Short QT syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46114
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79605
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.0187
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4798
NCI-H1755	COSMIC Cell Line Gene Mutation Profiles	1.0	null
stroke	GAD Gene-Disease Associations	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.6039
regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
TIMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29528
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22951
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.992743
receptor signaling protein activity	GO Molecular Function Annotations 2015	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07099
hsa-miR-3605-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31327
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38281
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	3.19133
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10042
POU5F1-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOP-92	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98812
potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
variants	GeneRIF Biological Term Annotations	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34459
pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.686776
modeling	GeneRIF Biological Term Annotations	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149838
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Childhood Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
HUCCT1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02607
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.48743
POU5F1	MotifMap Predicted Transcription Factor Targets	1.0	null
Benign familial infantile epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
H2731	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Thymus-mesothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00475801
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38866
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0748
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.03149
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05456
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65754
OPM2	CCLE Cell Line Gene CNV Profiles	1.0	1.53696
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KM12	DepMap CRISPR Gene Dependency	1.0	2.83231
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60893
CREB1	ENCODE Transcription Factor Targets	1.0	null
osteoporosis	GAD Gene-Disease Associations	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Familial adult myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TAX1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27805
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12621
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51002
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152432_6_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.07683
Perturb_6587_KO_Hira_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.329
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05257
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10994
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
K562_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202487
BLVRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04441
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0826
SCABER	CCLE Cell Line Gene CNV Profiles	1.0	1.64972
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38964
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858796
all	GWASdb SNP-Phenotype Associations	1.0	0.050473
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170059
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3472
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139491
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08031
hsa-miR-452	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX1_LHX1	Rummagene Transcription Factor Associations 2026	1.0	null
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.53772
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRAP_Deficiency_GDS3527_566_mouse_Brown adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0535
nh17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6538374-elife-45672-supp3.xlsx-DEGs-Genes_expressed_at_lower_levels_in_SMARCB1_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06862
voltage-gated potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.82
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50257
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26242
potassium ion transport	GO Biological Process Annotations 2015	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19767
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
colon	HPA Tissue Protein Expression Profiles	1.0	0.710719
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0999
K562_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150717
neurological	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68869
KMRC3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46638
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.85379
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056561
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.930981
K562_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155903
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1414
Fatty Liver	CTD Gene-Disease Associations	1.0	1.4332
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Perturb_13045_KO_Tmem259_SRP195618	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.20763
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13155
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fulvestrant_NCI-H1573	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0026754
MAFF	ENCODE Transcription Factor Targets	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063213
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22956
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849771
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29808
voltage-gated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23171
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Finding Of Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05644
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01979
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82889
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
REL	JASPAR Predicted Transcription Factor Targets	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35085
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15955
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05554
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1219
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12071
G-402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.273228
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.461852
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	0.710719
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27412
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7363
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4008
Psychiatric Status Rating Scales	HuGE Navigator Gene-Phenotype Associations	1.0	null
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9856
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
LSM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14994
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.389729
eb176	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.40496
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059787
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.53761
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41063
Cholesterol, HDL	dbGAP Gene-Trait Associations	1.0	0.1332
anemia	GWASdb SNP-Disease Associations	1.0	0.351251
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.82
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.44273
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845125
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	195.358
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955109
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35523
GP5D	DepMap CRISPR Gene Dependency	1.0	5.6961
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.298214
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042079
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07026
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Pitavastatin (Calcium)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0291157
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08645
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.145227
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23392
change	GeneRIF Biological Term Annotations	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895848
RRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.074
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46375
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09948
Perturb_4722_KO_Smarcc1/Smarcc2_SRP124677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.66345
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21516
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01165
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.61011
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989189
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25341
PC3	CCLE Cell Line Gene CNV Profiles	1.0	1.67823
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944269
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927678
methylation	GeneRIF Biological Term Annotations	1.0	null
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08428
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10054
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889058
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
signal transduction by phosphorylation	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30369
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07282
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27458
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38757
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833642
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53872
A673	CCLE Cell Line Gene Expression Profiles	1.0	1.50236
SFT2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10117
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
hsa-miR-555	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060101
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881825
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nucleus reuniens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
membrane part	GO Cellular Component Annotations 2015	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48222
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33064
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15435
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561245
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transferase activity, transferring phosphorus-containing groups	GO Molecular Function Annotations 2015	1.0	null
Perturb_9187_OE_NeuroD4_SRP390425	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	1.0	2.03785
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165883
demonistrated	GeneRIF Biological Term Annotations	1.0	null
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31682
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89605
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86697
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal anxiety-related response	MPO Gene-Phenotype Associations	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
HELZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00795
Resistin	dbGAP Gene-Trait Associations	1.0	0.147883
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.98029
Thymus-medullary thymic epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.21805
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7992
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.65271
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65584
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96919
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8353
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648532
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.23879
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	0.70084
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49886
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05463
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86415
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09353
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345314
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.65818
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PMC7056823-Table_1.docx-0-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10245
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841756
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04353
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08253
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75506
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51157
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
GSE146074_1_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87576
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05744
Criduchat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15061
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.38462
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155853
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15339
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88952
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96822
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
voltage-gated potassium channel complex	GO Cellular Component Annotations 2025	1.0	null
clcn4	GeneRIF Biological Term Annotations	1.0	null
PC3	DepMap CRISPR Gene Dependency	1.0	3.26941
glucose	GAD Gene-Disease Associations	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.626612
IM95	DepMap CRISPR Gene Dependency	1.0	2.1789
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
PGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14064
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58801
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03631
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03274
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.04647
frequently	GeneRIF Biological Term Annotations	1.0	null
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271174
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
hsa-miR-3942-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0704
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71727
SALL4	ChEA Transcription Factor Targets	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58781
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MESP1_cust_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1825
Brain disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89605
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.973208
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09523
Pemetrexed_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0222687
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63247
ATF1	ENCODE Transcription Factor Targets	1.0	null
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.206
NCIH1869	DepMap CRISPR Gene Dependency	1.0	4.16077
Tal-1beta:E47	MotifMap Predicted Transcription Factor Targets	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168247
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10882
Combined oxidative phosphorylation deficiency 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934983
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cell cycle G2/M phase transition	GO Biological Process Annotations 2025	1.0	null
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10776
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980813
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.44521
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GU-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423054
PDCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41186
CAKI1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0921
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.266
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31976
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138134
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9346
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.96243
PMC3500769-srep00875-s3.xls-CEBP-Time_24_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24634
TP53-18474530-U2OS-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1686
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0254
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06172
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1983
STAT3	ChEA Transcription Factor Targets	1.0	null
aging	GAD High Level Gene-Disease Associations	1.0	0.293278
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057194
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38678
KP1N	DepMap CRISPR Gene Dependency	1.0	4.24868
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Benign neonatal seizures	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
Diphenhydramine_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0223043
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222224
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_18112_KO_Eed_SRP132909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59367
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042046
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
Infratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.837134
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	2.47556
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.53206
hsa-miR-4638-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71661
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25388
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.182553
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30757
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HSC4	DepMap CRISPR Gene Dependency	1.0	5.69977
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32628
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69548
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40361
HCV_8week-No IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00814
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19443
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.050793
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.387365
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51002
hsa-miR-132	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37621
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
identification	GeneRIF Biological Term Annotations	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.43673
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27822
Proteinuria	CTD Gene-Disease Associations	1.0	1.39952
POU5F1	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84521
establishment of localization	GO Biological Process Annotations 2015	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907703
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
carotid artery diseases	GAD Gene-Disease Associations	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.86813
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
KMBC2	CCLE Cell Line Gene Expression Profiles	1.0	3.40758
Electrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
ion transport	GO Biological Process Annotations 2015	1.0	null
Docetaxel (Trihydrate)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0213227
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.45406
OC316	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36237
Tetracycline (hydrochloride)_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0249426
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878404
PAC motif	InterPro Predicted Protein Domain Annotations	1.0	null
Human - Motor Cortex - Cluster - RORB+ MED8+ Layer 5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A673	DepMap CRISPR Gene Dependency	1.0	4.69276
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66955
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.99698
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03697
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
CG-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
Transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05683
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38842
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10876
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD3epsilon deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
yy1_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.870008
lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.01174
NFYB	ENCODE Transcription Factor Targets	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86697
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	1.24623
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07367
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21299
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043511
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.889085
NERISPIRDINE	DGIdb Drug Targets 2026	1.0	0.13233
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899837
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2L2	ChEA Transcription Factor Targets	1.0	null
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834887
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
K562_BMS-536924_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153025
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.869706
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9625
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398357
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48993
K562_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140412
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Valdecoxib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0303268
Brain Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11399
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02483
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPK14_knockdown_139_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.51696
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03355
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13783
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.507105
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96865
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.703894
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348246
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Potassium channel, voltage-dependent, EAG	InterPro Predicted Protein Domain Annotations	1.0	null
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	3.2219
regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
hsa-miR-1976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171785
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03352
hsa-miR-487a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6199
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20274
abnormality of adipose tissue	GWASdb SNP-Phenotype Associations	1.0	1.00059
hsa-miR-4703-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44111
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H2029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830096
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12927
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.05828
arthritis	GWASdb SNP-Disease Associations	1.0	0.284216
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HS600T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86711
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6218
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
PECAPJ41CLONED2	CCLE Cell Line Gene CNV Profiles	1.0	1.84247
XRK3F2_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0270072
Weight Loss	CTD Gene-Disease Associations	1.0	1.14438
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 3 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34675
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35153
stabilizing	GeneRIF Biological Term Annotations	1.0	null
cell communication	GO Biological Process Annotations 2015	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_ZSCAN4-Unnamed_3_ZSCAN4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_14686_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.24017
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166507
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25173
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.249302
cellular potassium ion transport	GO Biological Process Annotations 2015	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14832
hsa-miR-4736	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
biological_process	GO Biological Process Annotations 2015	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.29935
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41247
Weight Gain	CTD Gene-Disease Associations	1.0	1.33434
OVCA420	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12129
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51013
2313287	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81854
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RUNX1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	1.0	1.71347
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05456
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0124
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069751
calmodulin binding	GO Molecular Function Annotations 2015	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913781
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6848
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25199
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Potassium channel, voltage-dependent, EAG/ELK/ERG	InterPro Predicted Protein Domain Annotations	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
demonstrate	GeneRIF Biological Term Annotations	1.0	null
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.632
icSARA deltaORF6_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.13122
PAS-associated, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21719
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14742
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061856
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09418
OACM5-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHH-NB-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885238
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858563
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50952
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21804
hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.595123
Ornidazole_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0204961
Perturb_7793_KD_UPF1_SRP049611	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66235
SOX2-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
culture condition	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
PMC4523944-DataSheet1.PDF-18-HMG20B_HMG20B	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01348
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
NCIN87	DepMap CRISPR Gene Dependency	1.0	5.86704
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11815
TIA1_KO_GSE54418_263_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
JM1	DepMap CRISPR Gene Dependency	1.0	2.18145
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15662
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09403
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902131
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09949
potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.61244
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_17291_OE_lncRNA5251_SRP239064	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.5677
Nephritis, Interstitial	CTD Gene-Disease Associations	1.0	1.03419
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15986
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Hyperpallium apicale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2163
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GF1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.240216
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.146
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11165
Ccrfsb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.847
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36432
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90398
Echocardiography	dbGAP Gene-Trait Associations	1.0	0.263613
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974384
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392001
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05537
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10455
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23825
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.48843
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	228.971
PMC10895040-Table_1.XLSX-Table_S8_-_mapped_genes-Table_S8_Positional_mapped_genes_of_110_IVs_for_pairs_of_microbial_features_and_MM_with_significant_P_value_in_two-sample_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.110218
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33637
RNF2-27304074-CHIP-SEQ-NSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.10329
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043731
localization	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09997
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7096
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19767
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61309
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922586
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22671
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7105
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61221
PMC9013323-13577_2022_685_MOESM7_ESM.docx-2-KLF5_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
abnormal emotion/affect behavior	MPO Gene-Phenotype Associations	1.0	null
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27799
immune system disease	GWASdb SNP-Disease Associations	1.0	0.112037
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
increased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39624
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04214
MTF2	ChEA Transcription Factor Targets	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61158
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16001_KO_TP53_SRP261893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14314
hsa-miR-3545-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
Perturb_14212_KO_Sp8/Sp8_SRP095936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NENF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05822
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047346
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41138
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868126
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
characterisation	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32074
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1994
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.858202
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04938
OAW42	DepMap CRISPR Gene Dependency	1.0	3.64383
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lacteal cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48332
PMC6275272-FEB4-8-1977-s006.docx-1-Supplementary_Table_S2_Upregulated_genes_under_MYC_knockdown_in_AMU-ML2_cells_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1454
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32194
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95055
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.110019
channel activity	GO Molecular Function Annotations 2015	1.0	null
Familial episodic pain syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
tissues	GeneRIF Biological Term Annotations	1.0	null
CHO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36428
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02474
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.54854
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.7413
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956139
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428018
single	GeneRIF Biological Term Annotations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.24027
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43252
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A520-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40997
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.24275
ZNF384	ENCODE Transcription Factor Targets	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59801
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.081806
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7483
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
Salt gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3122
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.424
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
K562_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166362
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08166
protein-containing complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
NCIH522	CCLE Cell Line Gene Expression Profiles	1.0	1.49189
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26885
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04233
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.129254
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.81089
Familial episodic pain syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
Trametinib_C-33 A	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0248496
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912047
Stroke	dbGAP Gene-Trait Associations	1.0	0.005588
Perturb_11899_KD_SRC1_SRP108577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_7906_KD_ZIP11_SRP363583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1298
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58363
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56431
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923537
Hyperpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
receptor activity	GO Molecular Function Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00594
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE111660_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48931
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12628
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Downregulated-Unnamed_7_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22756
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18052
NCI-H82	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
present	GeneRIF Biological Term Annotations	1.0	null
PMC3500769-srep00875-s3.xls-AP1-Time_4_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KE37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55304
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78411
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
vascular disease	GWASdb SNP-Disease Associations	1.0	0.212688
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62472