association	dataset	threshold value	standardized value
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898819
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Doxylamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Entinostat-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0238281
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
together	GeneRIF Biological Term Annotations	1.0	null
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16518
West Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18868
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.05692
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39005
A549_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229492
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.856327
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895451
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paroxysmal nonkinesigenic dyskinesia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
hsa-miR-3123	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2696
A549_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180638
A549_Alisertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0278994
A549_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159058
GSE248045,GSE248046_6_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.508424
A549_Avagacestat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176449
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53353
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.88654
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01327
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76397
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13673
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4520b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4205_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.49921
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Two pore domain potassium channel domain	InterPro Predicted Protein Domain Annotations	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10641
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936782
A549_Tazemetostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0268759
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17367
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13292
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10259
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986479
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061999
A549_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152966
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27858
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146924
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10486
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11537
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854345
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_Filgotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155919
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2458 (UBE2L3)	NURSA Protein Complexes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225273
A549_Pelitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0292186
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07178
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1583
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09452
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01265
obesity	GWASdb SNP-Disease Associations	1.0	0.717191
AZD-8055_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0243786
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57946
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_Inh L2 VIP SLC6A16	HuBMAP ASCT+B Annotations	1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46149
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09693
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16991
abnormality of the curvature of the vertebral column	GWASdb SNP-Phenotype Associations	1.0	0.510327
SKGT2	DepMap CRISPR Gene Dependency	1.0	3.49799
transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00756
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82757
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16991
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154791
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58006
Na<sup>+</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893174
SP1	ENCODE Transcription Factor Targets	1.0	null
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08805
Perturb_13852_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839135
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55001
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64046
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4782
A549_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248136
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824698
A549_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198932
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA	ChEA Transcription Factor Targets	1.0	null
CNOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07103
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XB-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHORBOL 12-MYRISTATE 13-ACETATE	DGIdb Drug Targets 2026	1.0	1.47033
hsa-miR-491-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
SUP-M2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	185.32
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45781
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.95122
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09183
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59165
K562_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173552
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
cellular_component	GO Cellular Component Annotations 2015	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15484
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875675
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
A549_TMP195_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239016
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18411
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9942
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57433
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
ovary	HPA Tissue Gene Expression Profiles	1.0	1.62479
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.166812
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097169
Autosomal recessive spinocerebellar ataxia 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
calcium activated cation channel activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5901
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XI-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5865663-oncotarget-09-14193-s002.docx-0-Supplementary_Table_S2_Somatic_mutation_Genes_which_are_high_frequency_in_TP53_signature_MT_TCGA_data_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	1.50411
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875001
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83284
A549_ITSA-1_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160814
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3942
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981214
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MK-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04779
NB10	DepMap CRISPR Gene Dependency	1.0	3.79599
A549_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0263279
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung_3f	HPA Tissue Sample Gene Expression Profiles	1.0	0.991724
K562_Droxinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217648
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cation channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A549_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205887
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kuhnt-Junius degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.069
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94703
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.99
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.27693
Partial motor epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
Adrenocortical carcinoma_ACC_TCGA-OR-A5KT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41746
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
segments	GeneRIF Biological Term Annotations	1.0	null
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	1.0	3.07932
A549_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223403
SNU46	DepMap CRISPR Gene Dependency	1.0	2.22571
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0383
A549_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0244011
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21867
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44849
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2831
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32078
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.389289
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.63513
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.52915
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.016
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Age-related macular degeneration (extreme sampling)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.30458
MRPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08301
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12641
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15765
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222635
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46487
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49932
A549_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171651
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830396
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5222
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	1.0	null
ion gated channel activity	GO Molecular Function Annotations 2015	1.0	null
tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213112
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
A549_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155058
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897194
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135185
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.53312
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858753
Von Willebrand Disease	DisGeNET Gene-Phenotype Associations	1.0	null
18280641-table2	GeneSigDB Published Gene Signatures	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.146018
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.284013
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39314
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07833
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3792-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Canagliflozin (hemihydrate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0381066
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51049
potassium ion export across plasma membrane	GO Biological Process Annotations 2025	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10463
PMC7021759-41467_2020_14682_MOESM8_ESM.xlsx-Upregulated_Genes-Table_S5_Upregulated_genes_in_MYCN_amplified_neuroblastoma_relative_to_non-amplified_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150072,GSE169209_4_v_10_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12736
A549_BMS-754807_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0232687
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cannabis abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03178
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47379
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Pirarubicin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151051
Necrosis	CTD Gene-Disease Associations	1.0	1.40008
GSE148262,GSE150691_1_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959446
A549_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134332
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63134
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Streptozotocin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167191
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.465486
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.567
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07403
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.909
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151925
RKN	DepMap CRISPR Gene Dependency	1.0	4.01372
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.24331
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97442
Perturb_6485_OE_LncRNA XLOC013218_SRP367251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.00775
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894121
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NP-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09542
A549_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162039
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964002
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051569
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
A549_INO-1001_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139949
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73829
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55936
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08845
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158729
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48752
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10512
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.235
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06699
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.34927
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06728
Progressive bulbar palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
A549_Divalproex Sodium_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162053
electrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449116
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-1126-SM-4E3I1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13279
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908278
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79406
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.939
Dendrite membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92282
Temsirolimus_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0190094
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9289
A549_Abexinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0308273
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gates	GeneRIF Biological Term Annotations	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35932
Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32777
A549_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017571
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.32146
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.919013
cellular process	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69288
Benign neonatal seizures	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
A549_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210665
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Daphnetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134362
potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49169
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40988
hsa-miR-502-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52807
Lung adenocarcinoma_LUAD_TCGA-44-6145-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3162-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
A549_Resminostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155583
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22468
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838883
Vemurafenib_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0219956
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.085115
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1667
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02481
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871975
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913301
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00211
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06787
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833643
A549_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165064
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23776
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41872
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_BMS-754807_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204146
TETRAMETHYLAMMONIUM	DGIdb Drug Targets 2026	1.0	0.367583
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03086
A549_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228205
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97899
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26291
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Crizotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202162
GSE132369,GSE132371_5_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.861961
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
A549_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0231953
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3714	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Retinoic acid_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0281051
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993405
immune system disease	GWASdb SNP-Disease Associations	1.0	0.096718
A549_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125435
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Perturb_4976_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.54319
A549_Zileuton_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203502
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
GTEX-REY6-0926-SM-48FDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825164
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17201
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15389
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45102
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175676
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8765
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03579
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.198
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15426
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909252
Perturb_4979_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.09601
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
decreased locomotor activity	IMPC Knockout Mouse Phenotypes	1.0	null
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15879
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871178
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06623
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
JUN	ENCODE Transcription Factor Targets	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39765
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.12045
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
transmembrane transporter complex	GO Cellular Component Annotations 2015	1.0	null
connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20977
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	1.45324
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11935
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22259
cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18313
PMC12337709-mmc3.xlsx-Wild-type_vs_RAG1_KO_Myeloid-Unnamed_1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
localization	GO Biological Process Annotations 2015	1.0	null
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
A549_Panobinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152224
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21968
Visceral hump	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35932
A549_Ellagic acid_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126085
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-427-NFIX_NFIX	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18899
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03732
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.158255
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.12201
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47461
Prostate adenocarcinoma_PRAD_TCGA-EJ-5526-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sirt1_OE_GDS2658_140_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12173
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872638
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00691
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
TOV112D	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45102
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10915192-ab-23-0304-Supplementary-Table-S6.pdf-6-TEF_TEF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40681
hsa-miR-3972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0274
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19306
Pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08056
GTEX-QDVN-0126-SM-4GIC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34503
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.462619
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03001
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30568
SNUC5	DepMap CRISPR Gene Dependency	1.0	2.34188
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16283
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62704
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.200239
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954734
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46279
SIN3A	ENCODE Transcription Factor Targets	1.0	null
abnormality of coagulation	GWASdb SNP-Phenotype Associations	1.0	1.28088
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857247
JHU022	DepMap CRISPR Gene Dependency	1.0	2.26711
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915408
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31631
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15753
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07301
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911643
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4353
Lung adenocarcinoma_LUAD_TCGA-49-6744-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
VIPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18466
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0119
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7260947-pnas.1912355117.sd02.xlsx-Sheet1-1185_common_genes_in_D_E_genes_KD_and_AcAPE1_ACOGG1_G4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09392
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
permeation	GeneRIF Biological Term Annotations	1.0	null
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958407
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pyridoxine (hydrochloride)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0254208
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.88617
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.332294
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90512
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34572
Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Sodium Phenylbutyrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190962
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.758519
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19786
CBX2_KO_GDS4445_353_mouse_E11.5 XX embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06954
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-376a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846107
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13975
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20128
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2463
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the vertebral column	GWASdb SNP-Phenotype Associations	1.0	0.196972
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.0259
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834685
CBX3	ENCODE Transcription Factor Targets	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205259
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16412
12734205-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174657
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
reading disorder	GWASdb SNP-Disease Associations	1.0	0.457463
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5956
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreatic ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.772759
Ba<sup>2+</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.163429
mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
Perturb_17289_OE_lncRNA5251_SRP239062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.87173
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.696
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19975
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_2_TBRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19092
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89767
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
FOXP2	ChEA Transcription Factor Targets	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0615
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29555
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41937
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.45473
M07E	DepMap CRISPR Gene Dependency	1.0	2.7303
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07827
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982951
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991077
bone disease	GWASdb SNP-Disease Associations	1.0	0.203855
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934834
A549_Hesperadin_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164839
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3087
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	1.51241
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.876
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1119
Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Human - Heart - L2 - Mesothelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63998
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46225
A549_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0252255
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071777
Post bronchodilator FEV1	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
A549_AZ 960_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0233246
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09503
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
A549_EED226_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0121936
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931897
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7339
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60847
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896226
specific developmental disorder	GWASdb SNP-Disease Associations	1.0	0.171657
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
EWS502	Achilles Cell Line Gene Essentiality Profiles	1.0	1.104
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40245
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893174
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.81301
A549_Ruxolitinib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130058
Perturb_6284_OE_CPEB3_SRP364591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_1100_KO_Perk_SRP370072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.531154
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13612
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848965
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69165
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S4-Supplemental_Table_S4_Differentially_expressed_genes_between_cases_with_G-CSF-induced_pY-STAT3_DMFI_1_5_STAT3_Low_v_DMFI_1_5_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
A549_Resveratrol_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213153
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337072
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2103
APTO-253_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0275586
monoatomic ion gated channel activity	GO Molecular Function Annotations 2023	1.0	null
Primary somatosensory area, unassigned, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20819
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09016
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30814
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
A549_Lenalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0312667
Paclitaxel_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0260567
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965783
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
MXI1	ENCODE Transcription Factor Targets	1.0	null
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.694
Malotilate_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0233767
A549_Danusertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189274
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47226
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein complex	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
potassium ion transport	GO Biological Process Annotations 2015	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05874
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29555
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.129
Perturb_7611_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.6265
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
Perturb_123_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.8356
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879027
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96826
PMC3500769-srep00875-s3.xls-GATA3-Time_1_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27672
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55823
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932323
Lateral loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_24_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13374
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22296
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
PMC3500769-srep00875-s3.xls-GATA3-Time_24_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28373
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62616
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	1.72642
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.574994
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14084_KD_FGF13_SRP114701	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.299
retinal degeneration	GWASdb SNP-Disease Associations	1.0	1.27692
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.53328
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06478
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0119
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37944
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21602
A549_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187563
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4015
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.8084
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14879
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15797
Idiopathic dilated cardiomyopathy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	2.73962
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.493
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997316
A549_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208186
BXPC3	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NS1619	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_4_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30568
Chronic Central Serous Chorioretinopathy	DisGeNET Gene-Disease Associations	1.0	null
A549_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0238534
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13232
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827253
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01937
potassium ion export across plasma membrane	GO Biological Process Annotations 2023	1.0	null
PMC6293073-LSA-2018-00153_TableS3.xlsx-B_KD_Tr_2_genes-155_genes_upregulated_upon_knockdown_of_Tr_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0107
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062715
pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.807299
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
outward rectifier potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
PMC5986551__F5	PFOCR Pathway Figure Associations 2024	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5199
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939592
A549_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172391
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7153
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86872
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.016
GTEX-O5YW-3026-SM-3MJHI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0347
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851646
layer 6 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11931
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044271
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Alisertib_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200007
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15147
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18608
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13684
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901788
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059943
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826385
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-2.90716
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849091
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1702
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.091389
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.3756
Cardiomyopathy_Myocardial tissue_GSE5406	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.60786
stomach	HPA Tissue Protein Expression Profiles	1.0	0.929222
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31044
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896801
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3682-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Schwalie et al.Nature.P3_Adipose tissue_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
A549_Luminespib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138864
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12641
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0637
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27945
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836182
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BL-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSS	DepMap CRISPR Gene Dependency	1.0	2.23612
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02299
A549_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145561
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06637
Dystonia 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
A549_BRD4770_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157323
A549_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154869
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.75438
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COMPOUND 43 [PMID: 37812884]	DGIdb Drug Targets 2026	1.0	6.6165
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Uridine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0226347
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Aurora A Inhibitor I_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148134
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63154
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-592	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0254754
GTEX-Q2AH-0626-SM-48TZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70232
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.544
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40757
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2341
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.533083
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873038
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936903
developmental disorder of mental health	GWASdb SNP-Disease Associations	1.0	0.142894
A549_Tazemetostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0279016
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914564
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx SalivaryGland 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.53895
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09748
NCIH508	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59021
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30662
Cytosolic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
PADI4-21655091-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829103
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955439
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.83751
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17867
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63956
macular degeneration	GWASdb SNP-Phenotype Associations	1.0	2.14243
SIRT6	ENCODE Transcription Factor Targets	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970383
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
A549_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203159
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	316.953
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987041
Lissencephaly 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
A549_ZM 447439_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116841
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07036
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851368
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
A549_Tranylcypromine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219275
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE221004_1_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05302
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	3.03666
A549_Selisistat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200011
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016569
A549_Pracinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187177
HT29	DepMap CRISPR Gene Dependency	1.0	4.67074
A549_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193968
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25804
A549_Nilotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0286618
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14301
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1662
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Irinotecan_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0266228
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.856
PTEN_KD_GDS2958_101_human_SKBR-3 MAMMARY ADENOCARCINOMA cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046243
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09413
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45354
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57515
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epilepsy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
chloride-activated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06748
A549_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0285408
A549_INO-1001_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139441
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022247
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952542
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832004
A549_Panobinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0100613
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.9693
AR	ChEA Transcription Factor Targets	1.0	null
heparin_homo sapiens_gpl570_gse12710	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
M/G1 phase-specific MADS box-forkhead transcription factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4395
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bag cell neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9942
FLO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74638
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835623
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03548
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999149
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912249
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.775
A549_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212423
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63006
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.6784
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0330162
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47909
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ampicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.354834
PMC12171002-jcav16p2578s1.pdf-16-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-500b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09839
A549_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195888
GTEX-PWN1-2426-SM-48TDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1964
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0688
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_PHA-680632_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132766
GTEX-WFON-1026-SM-4LVMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933301
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877211
HCC1187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09346
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7996-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_SRT2104_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149774
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46441
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944398
Adolescent Idiopathic Scoliosis	DisGeNET Gene-Disease Associations	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1223
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11685
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transporter complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21198
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01804
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893655
A549_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198251
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19203
19286929-SuppTable2h	GeneSigDB Published Gene Signatures	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Aurora A Inhibitor I_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150222
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.088691
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WFG7-0426-SM-4LMK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09747
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12261
UWB1289	DepMap CRISPR Gene Dependency	1.0	3.84546
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873359
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Early infantile epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.181
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67261
M059J	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180414
Lung adenocarcinoma_LUAD_TCGA-44-2661-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laminin-9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074835
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908418
hsa-miR-4305	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12212
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K029AX	DepMap CRISPR Gene Dependency	1.0	2.78937
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
Tomivosertib_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0175381
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35688
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0259022
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013832
Verapamil_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0167133
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60733
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.75
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177847
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06831
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
A549_PFI-1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112279
Fibrosis	CTD Gene-Disease Associations	1.0	1.18026
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5798892-41421_2017_3_MOESM9_ESM.xlsx-IARGs-MSC-Supplementary_Table_4_Gene_list_for_IARGs_and_CARGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201535
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978493
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
d2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89387
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07724
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26491
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19935
Bergenin_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0213284
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0256768
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
A549_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169171
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05152
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	1.0	3.31189
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74888
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_JQ1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146876
A549_JQ1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226023
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16621
Zymogen granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23778
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14059
A549_SRT1720 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015331
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11173
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85107
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3617	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55921
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22355
EP300	ENCODE Transcription Factor Targets	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069426
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LNZ308	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.85003
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930305
Perturb_4276_KO_Smad2/Smad3_SRP132215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.3845
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834785
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.865962
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63055
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.889832
A549_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0197217
DKMG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24886
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16348
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15632
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NB4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07886
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973415
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.868719
20081105-ST-2	GeneSigDB Published Gene Signatures	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.694
A549_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165711
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836654
hsa-miR-4307	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22569
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016185
Heart-fibroblast of cardiac tissue	Tabula Sapiens Gene-Cell Associations	1.0	1.27023
A549_JQ1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130357
Perturb_13451_OE_PAX8NFE2L2_SRP072669	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.14575
A549_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162325
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4733
Agranular insular area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05421
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
GSE144443_5_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27672
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.089654
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PJ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63218
potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pore	GeneRIF Biological Term Annotations	1.0	null
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
A549_Tubastatin A HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147361
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975147
SMAD4	ChEA Transcription Factor Targets	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01664
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronotype	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00969
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200121
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93033
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29629
all	GWASdb SNP-Phenotype Associations	1.0	0.071826
CHD7	ENCODE Transcription Factor Targets	1.0	null
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
A549_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0272257
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.775
Total ventricular volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.77888
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	2.02613
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3667
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.27544
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11764
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
A549_Aurora A Inhibitor I_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186236
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15057
A549_ITSA-1_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211595
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987052
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.237992
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46279
A549_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0264886
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.566
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.450701
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05444
A549_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195105
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06937
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220014
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02337
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0235492
A549_TMP195_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160622
TC138	DepMap CRISPR Gene Dependency	1.0	2.63359
GTEX-U3ZN-2526-SM-3DB7V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980679
A549_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203026
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.679
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33047
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39573
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.44327
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
K562_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126967
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972879
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62664
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.899
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.71
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0727
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66018
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4056
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29359
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29393
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40518
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27826
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SRT2104_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217995
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160978
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64871
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29077
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Vismodegib-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10827
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
nasopharynx	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984645
A549_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186591
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3881
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12978
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.016
SUIT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35105
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
SKRC31	CCLE Cell Line Gene CNV Profiles	1.0	1.4304
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980582
Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Pracinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196202
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913127
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49035
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Myometrial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826115
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94806
PMC4521181-oncsis201520x8.pdf-89-TBX15_TBX15	Rummagene Transcription Factor Associations 2026	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947202
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130521
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29221
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95008
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	2.33004
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05819
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04866
bone structure disease	GWASdb SNP-Disease Associations	1.0	0.60074
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832972
age related macular degeneration	GWASdb SNP-Disease Associations	1.0	2.19599
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934406
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16496
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.50866
tetraethylammonium	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
hsa-miR-1253	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.073
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.62703
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bundle	GeneRIF Biological Term Annotations	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.280321
A549_Belinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171896
SJRH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88441
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
A549_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184738
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12633
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03523
K562_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0223429
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987269
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
A549_Alisertib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152327
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Exudative Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878994
NB4	DepMap CRISPR Gene Dependency	1.0	2.47402
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_fMSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0715
Developmental and epileptic encephalopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.096
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.182638
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29118
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04838
Developmental and epileptic encephalopathy 57	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.509
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YO-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dynamic	GeneRIF Biological Term Annotations	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04904
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86649
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16496
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.045441
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42494
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Cannabis dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
ntera2	HPA Cell Line Gene Expression Profiles	1.0	0.909032
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.617647
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4327
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30631
FOXP2	ENCODE Transcription Factor Targets	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0115077
F5	CCLE Cell Line Gene Expression Profiles	1.0	2.01118
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877018
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42243
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.861322
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13232
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.392
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15127
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05586
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.795869
20421987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855526
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7202
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
voltage-gated ion channel activity	GO Molecular Function Annotations 2015	1.0	null
Hallucinogen dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.099
Naproxen_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.022941
A549_Divalproex Sodium_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121965
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05511
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895397
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979704
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86348
OPTN_KD_GDS2892_268_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17362
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3456
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70408
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.197766
A549_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182985
Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	9.80518
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06255
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
A549_Fasudil_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219487
K562_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174435
A549_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151979
layer 4 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00478
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
HS766T	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2421
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small spleen	MGI Mouse Phenotype Associations 2023	1.0	null
FUS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
layer 6 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31528
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33878
cation transport	GO Biological Process Annotations 2015	1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115768
Econazole_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0239469
Tucidinostat_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.019992
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834781
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884946
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
chr1_196544193_A_G_b38	GTEx eQTL 2025	1.0	1.55674
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11292
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57512
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128456
SW626	DepMap CRISPR Gene Dependency	1.0	4.96813
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827981
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06971
GTEX-S4P3-1826-SM-3K2AL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55946
PMC4070589-NIHMS573166-supplement-1.pdf-106-SPEN_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7140408__F6	PFOCR Pathway Figure Associations 2024	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06701
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.39298
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46441
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64821
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02177
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23458
potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TGFBR2_KO_GDS5008_282_mouse_Embryonic palatal mesenchymal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7255
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78521
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perineuronal net	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4301
Busulfan_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0112668
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22475
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993588
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
potassium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16621
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871984
RINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00681
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86925
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850208
dyslexia	GWASdb SNP-Disease Associations	1.0	0.82519
hsa-miR-582-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3541
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8759
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90782
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SARS-CoV MA15_Day4-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.16305
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04618
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	0.830564
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Gangliocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0252768
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2674
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.878956
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489057
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.957429
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02577
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898165
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36306
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75538
A549_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191872
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11497
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169418
SETDB1	ENCODE Transcription Factor Targets	1.0	null
SU-DHL-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45797
Perturb_4972_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.3171
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38635
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59973
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Perturb_8517_OE_CamkdeltaC_SRP287242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.57317
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13585
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
A549_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174875
SMARCA4	ChEA Transcription Factor Targets	1.0	null
A549_Danusertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0266998
para-high vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
A549_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131843
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071899
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11816
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ligand-gated monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
A549_PHA-680632_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182417
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064906
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04639
hsa-miR-4496	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	2.5311
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10042
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.40827
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4095
hsa-miR-3157-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987473
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Human - Heart - L1 - Mesothelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29149
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27672
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982032
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR1I2-20693526-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.257929
Agranular insular area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10416
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857029
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83153
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Asciminib_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0243057
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895094
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09326
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51565
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910078
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27383
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HPAC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.903057
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69995
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_BMS-754807_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234232
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02325
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07069
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33175
PMC5986551__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-PLZ4-2826-SM-3P617	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35462
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32793
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827481
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891209
Decitabine_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0188049
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96915
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8257
electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A815-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Verapamil_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0288597
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24686
hsa-miR-4698	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
A549_ABT-737_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229888
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H841	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16145
cloning	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17828
LOVO	DepMap CRISPR Gene Dependency	1.0	4.68105
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106557
Dihydroartemisinin_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0245458
muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166058
HCV JFH1_168Hour-Huh7_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39959
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Clark-Baraitser syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20819
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.55366
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33725
Brain Lower Grade Glioma_LGG_TCGA-HW-8319-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U343	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09681
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73524
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182442
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876926
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42256
c-reactive protein	GAD Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymus-medullary thymic epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.729184
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90634
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.62927
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833851
macular degeneration	GAD Gene-Disease Associations	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07923
sublayer 6a of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10074
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36317
chloride channel activity	GO Molecular Function Annotations 2023	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12065
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00075
NCO2	DepMap CRISPR Gene Dependency	1.0	5.13576
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63691
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35932
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_SRT2104_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018178
A549_FLLL32_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123921
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07593
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
A549_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149357
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	3.04733
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Harringtonine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0142237
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59181
Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2835
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.982849
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.21193
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52339
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.55188
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88733
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36316
A549_Daphnetin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162245
blood coagulation disease	GWASdb SNP-Disease Associations	1.0	1.45324
sevoflurane_homo sapiens_gpl570_gds2772	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	1.0	1.50698
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20763
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6558
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.176189
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87235
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15183
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postsynaptic endocytic zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
Cyclosporin A_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0243712
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.068981
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.74084
Riluzole hydrochloride_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.017881
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K562_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159144
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884943
FURIN_Deficiency_GDS3512_568_mouse_T-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2235
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959828
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942632
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059836
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87546
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35738
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81718
potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985215
Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE206400_1_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8263
A549_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157321
Heart Diseases	CTD Gene-Disease Associations	1.0	1.19574
PRECLH	CCLE Cell Line Gene Expression Profiles	1.0	1.77233
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21837
PC-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.17182
voltage-gated potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A_CA_04_2009_7dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51087
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37563
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
17880687-TableS1	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-1264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6428
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
A375	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10238
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379499
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146934
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011056
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25276
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17656
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09949
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15021
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901835
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05204
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06701
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_JQ1_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138357
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916985
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
K562_Dasatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016514
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9941
A549_Abexinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0259797
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.974559
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.50942
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	2.2266
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18214
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Andarine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152737
Geographic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE98579_0_v_1_tfam_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
cell part	GO Cellular Component Annotations 2015	1.0	null
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Tacedinaline_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022229
selectivity	GeneRIF Biological Term Annotations	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36798
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15507
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20769
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.546763
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.65067
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
testis	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lactate (calcium)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0154799
Inflammation	CTD Gene-Disease Associations	1.0	1.4612
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7406
channel activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.766
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065665
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.453
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-KLF4_correlates_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Silodosin_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0294643
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041433
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1599
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181052
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26978
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13488
Perturb_7612_KD_PARP1_SRP410217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3122
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18552
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZEB2_01_56	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58715
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
Perturb_1020_KO_Apoe/Apoa1_SRP318735	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21666
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Secretory progenitor cell_Small intestine_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05538
monoatomic ion-gated channel activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
A549_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135182
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
A549_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158999
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31713
Hereditary renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.85688
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Generalized epilepsy with febrile seizures plus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Familial isolated trichomegaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
RT112	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61025
A549_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196371
CCDC121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86754
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.67067
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30503
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952256
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00326
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	1.01861
Flumatinib (mesylate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0239573
Lung adenocarcinoma_LUAD_TCGA-44-6776-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.79327
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
Age-related macular degeneration	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.1
arthritis	GWASdb SNP-Disease Associations	1.0	0.263719
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96724
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907918
A549_JNJ-7706621_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0331399
Cl<sup>-</sup>	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12368524-Supplementary_materials.pdf-33-DZIP1_DZIP1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.95105
intracellular sodium activated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0946
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28594
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17946
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24609
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04884
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956344
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	2.20456
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Familial temporal lobe epilepsy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
PADI4	ChEA Transcription Factor Targets	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44131
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866441
A549_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143897
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969087
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
intracellular sodium-activated potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62725
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.6446
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.82786
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7497
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18777
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043689
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
AGS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A549_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230854
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24501
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928117
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Seizure	ClinVar Gene-Phenotype Associations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946756
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.63391
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886918
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_2-Methoxyestradiol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204617
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901341
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13746
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.211
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4113-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926873
GSE158320,GSE183351_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-501-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77435
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06701
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11483
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78711
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30372
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28457
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75296
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849245
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08855
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49697
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4918
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19662
Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26243
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0626
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32688
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04236
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37116
Developmental and epileptic encephalopathy 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
A549_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248174
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
retinal disease	GWASdb SNP-Disease Associations	1.0	0.545989
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61198
PMC9377669-tx1c00392_si_002.xlsx-Valproic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.341272
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06269
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2547
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13250_KO_Mettl14_SRP182641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1016
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14646
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94674
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48143
Seizures, Focal	DisGeNET Gene-Phenotype Associations	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980101
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93555
overnutrition	GWASdb SNP-Disease Associations	1.0	0.444962
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Iniparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166384
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842869
SW948	DepMap CRISPR Gene Dependency	1.0	4.00176
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GK_KO_GDS2610_162_mouse_Brown adipose tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25863
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85123
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.884978
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07617
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.75487
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0199
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24838
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79125
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37094
REST	ENCODE Transcription Factor Targets	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
Episodic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
A549_AZD1480_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143211
small spleen	IMPC Knockout Mouse Phenotypes	1.0	null
Carbidopa (monohydrate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0280896
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0391
GSE233679_6_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_Inh L2 VIP SLC6A16	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8754
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78477
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890872
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47449
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25838
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908104
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14498
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.530768
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.214934
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28095
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24365
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3246
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.58487
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51561
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6A-targets_down-EWSR1_FLI1-KDM6A_downregulated_targets_upon_KDM6A_knockout_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4690-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13486
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04533
AGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27592
Hyperplasia	CTD Gene-Disease Associations	1.0	1.44899
single-organism process	GO Biological Process Annotations 2015	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987147
CBX2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
x-linked disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.911022
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932834
TAF15-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942632
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8063
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.32295
A549_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0184364
quinidine	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724453
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19898
MM485	DepMap CRISPR Gene Dependency	1.0	4.96756
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03024
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM14-20953172-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170432
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03328
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
A549_JNJ-7706621_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182695
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068646
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0149
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.081608
GTEX-S4Z8-2026-SM-3K2A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11445
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.036424
anion binding	GO Molecular Function Annotations 2015	1.0	null
A549_PCI-34051_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176371
WM115	DepMap CRISPR Gene Dependency	1.0	2.33379
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.8821
Adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.881
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COQ10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13471
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27676
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
A549_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0224023
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37868
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31606
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5223
Developmental Regression	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-4789-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
EW-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30975
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48446
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATR_knockdown_140_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.97603
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33417
GSE180951_2_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
charybdotoxin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0271
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999423
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A427	DepMap CRISPR Gene Dependency	1.0	5.88379
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05393
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33122
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Takayasu arteritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28095
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9710014-12876_2022_2535_MOESM2_ESM.pdf-40-ZFP82_ZFP82	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Roxadustat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0238642
A549_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0264009
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20042
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993566
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53942
A549_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.033186
hsa-miR-3670	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
myoclonic-atonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
EN	DepMap CRISPR Gene Dependency	1.0	2.48774
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936137
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22998
A549_Filgotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0260709
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25621
PMC9377669-tx1c00392_si_002.xlsx-5_5-Diphenylhydantoin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26901
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987609
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96774
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0574
gamma-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
A549_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0238267
GTEX-PSDG-0826-SM-48TCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25393
abnormal axial skeleton morphology	GWASdb SNP-Phenotype Associations	1.0	0.133393
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7140408__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4225
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98008
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1915
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05935
Atypical Absence Seizure	DisGeNET Gene-Disease Associations	1.0	null
GSE180951_6_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870287
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0613
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Mouse - Motor Cortex - Cross-Species Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12768
PMC12208648-txd-11-e1829-s001.pdf-26-IRF8_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68536
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.15748
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64476
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF1-19129219-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
A549_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01498
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b69	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4618
A549_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159638
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0573
NB1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S7-Supplemental_Table_S7_Genes_that_are_commonly_upregulated_in_both_pY-STAT3_Low_groups_v_pY-STAT3_High_groups_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80232
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.036
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YKG1	DepMap CRISPR Gene Dependency	1.0	3.20237
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82448
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13374
A549_BMS-265246_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0279358
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896647
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988285
Sulfisoxazole_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0202801
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
Pitavastatin (Calcium)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0272847
neurodevelopmental abnormality	GWASdb SNP-Phenotype Associations	1.0	0.720196
A549_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0270347
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90772
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89104
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3403
Pyromania	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
PMC9377669-tx1c00392_si_002.xlsx-Folic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Macular Degeneration	dbGAP Gene-Trait Associations	1.0	1.60654
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19418
GSE180951_1_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146936
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09203
Hypertrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48269
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05949
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08332
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42716
A549_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225993
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0119
A549_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013886
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC30A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08805
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948843
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TTT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.858
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.258064
Sperm cytoplasmic droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41782
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02693
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19372
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1902
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
K562_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158919
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01689
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42225
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30228
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153233
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.85687
hsa-miR-630	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ponatinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0203508
A549_BRD4770_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180056
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
A549_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144229
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135085
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884583
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
Fibroblast_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837946
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48672
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202208
helix	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958751
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88744
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03167
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041162
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.02971
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	0.615445
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171572
A549_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167303
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04017
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910475
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Arterial smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04843
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03167
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10416
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54574
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02235
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
degeneration of macula and posterior pole	GWASdb SNP-Disease Associations	1.0	2.19599
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067803
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869883
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067217
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131308
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73917
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.530885
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26684
TAK-901_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00695466
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31781
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07885
LP-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3500769-srep00875-s3.xls-CEBP-Time_24_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.52915
PTEN_01_303	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.20347
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SOCS3_KO_GDS3149_8_mouse_multiple cell types	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10004
Perturb_10893_KO_Jnk1_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.32226
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Resveratrol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177761
RCOR1	ENCODE Transcription Factor Targets	1.0	null
West syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
Pathological gambling	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183468
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00982
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0574
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI1	DepMap CRISPR Gene Dependency	1.0	2.12428
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NR2F2_NR2F2	Rummagene Transcription Factor Associations 2026	1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55595
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098055
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04844
GTEX-RUSQ-0426-SM-47JWR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5005
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71188
Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALR_KO_GDS3680_149_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lennox-Gastaut Syndrome	DisGeNET Gene-Disease Associations	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071058
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ChEA Transcription Factor Targets	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl570_gse37474	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NS004	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08891
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41458
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_17229_KO_Tsc1_SRP096336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.6198
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8575
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6002
K562_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153889
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10303
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
F36P	CCLE Cell Line Gene Expression Profiles	1.0	1.97461
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE214823,GSE214824_6_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-1126-SM-3NMBY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78111
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842491
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19833
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0726-SM-4GIAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06084
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951257
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95056
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vomeronasal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40842
A549_MC1568_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234944
IgA glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.775
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6397
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
E2F6	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918772
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20068
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
A549_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174741
A549_Tranylcypromine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137831
A673	Achilles Cell Line Gene Essentiality Profiles	1.0	1.58242
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03381
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27224
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03743
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A549_Roscovitine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151016
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58495
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864694
GTEX-X261-0926-SM-3NMCY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0005
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PK45H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52154
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162486
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_CUX2-Unnamed_6_CUX2	Rummagene Transcription Factor Associations 2026	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181229
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
A549_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142706
A549_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020067
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_JQ1_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108355
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979354
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0443
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6651
A549_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01591
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897111
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895587
SERBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04529
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant nocturnal frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.244
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
Vasculature-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	0.226785
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080361
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23217
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631931
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134732
A549_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163198
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.26767
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10673
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901128
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100655
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.82439
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02347
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58264
A549_Divalproex Sodium_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0393349
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
MYC	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6743-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53464
ion channel complex	GO Cellular Component Annotations 2015	1.0	null
ion	GeneRIF Biological Term Annotations	1.0	null
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01599
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
JUND	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01911
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
KP363T	DepMap CRISPR Gene Dependency	1.0	3.42618
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5082
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
hsa-miR-642b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27895
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45378
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.03869
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01209
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03027
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adult body size	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15701
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871178
A549_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166775
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52467
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0209809
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19433
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
A549_Dacinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149884
HS944T	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05775
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840858
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03027
Perturb_130_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11771
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912946
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071024
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20188
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHP212	CCLE Cell Line Gene Expression Profiles	1.0	1.35378
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081884
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63981
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07289
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90634
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995258
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.41811
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5858
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.60283
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890175
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.19344
calcium-activated potassium channel activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974937
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.47773
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_AICAR_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210889
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01085
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93619
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64348
A549_BMS-911543_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166253
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3146
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23583
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.712796
A549_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0200196
A549_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0329696
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spinocerebellar ataxia 45	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Topotecan (hydrochloride)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0208141
K562_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201551
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
UACC893	DepMap CRISPR Gene Dependency	1.0	4.69717
potassium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39184
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41101
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30034
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Resveratrol_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.030345
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82338
Encorafenib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0226469
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_B-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.725685
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.0027
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.156135
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04082
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46939
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
binding	GO Molecular Function Annotations 2015	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
A549_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015957
A549_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189789
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07273
A549_UNC1999_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133425
Perturb_11055_KO_Stab1_SRP149099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2245
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1877
A549_Pracinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0261735
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20521
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08833
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
cation channel activity	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.29978
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.368619
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852603
A549_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0251268
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35632
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11258
A549_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213291
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93516
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2834
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52758
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20819
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994993
GTEX-OHPN-2826-SM-3LK67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871641
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31884
FOXP2-23625967-PFSK-1-AND-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56404
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1452
K562_ENMD-2076 L-Tartaric acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215047
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3146
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34502
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	3.42819
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.54497
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03881
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68091
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54469
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228101
POLR2A	ENCODE Transcription Factor Targets	1.0	null
MUTZ5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37952
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.197045
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18596
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907412
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE60837_6_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18387
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99221
hsa-miR-451b	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17615
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	0.806326
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4329
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30674
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39781
Geep	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Fostamatinib (disodium hexahydrate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0135619
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942632
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939504
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11228
CLOFILIUM	DGIdb Drug Targets 2026	1.0	1.65412
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.186024
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.947544
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215407
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41642
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830427
A549_ITSA-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136143
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02711
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2052	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.17182
REH	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02176
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49008
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05285
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Kenyon cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.24197
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05471
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186815
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.1078
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158449
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HPAF-II	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911187
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59093
fragile x syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10594
hsa-miR-4529-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.596
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13797
A549_Azacitidine_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241683
Perturb_9622_OE_Mir155_SRP295675	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.10274
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOCS3_KO_GDS3149_297_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17307
A549_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015454
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936258
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.821336
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92627
A549_Rucaparib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.030199
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ES5	DepMap CRISPR Gene Dependency	1.0	4.83445
Bruxism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67178
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.173
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD3-22036565-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GOLGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12272
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50955
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IRF1-19129219-H3396 breast cancer cells-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921981
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13333
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717472
sublayer 6b of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17241
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CP21R7_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0217595
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_JNJ-26854165_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171575
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.1694
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	2.4876
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01587
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25396
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_ZM 447439_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204769
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Perturb_13045_KO_Tmem259_SRP195618	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.97098
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892747
cellular potassium ion transport	GO Biological Process Annotations 2015	1.0	null
TAL1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00982
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75684
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27189
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.40827
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48925
voltage-gated potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
A549_Bosutinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225572
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08527
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89651
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00878
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29387
Liver Diseases	CTD Gene-Disease Associations	1.0	1.07625
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.859118
Benign epilepsy with centrotemporal spikes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69782
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40973
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12172
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
JHH-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1693	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86298
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41683
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17095
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09993
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_UNC0379_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192592
PMC8390401-12094_2021_2621_MOESM2_ESM.xls-S5-Supplemental_Table_S5_Differentially_expressed_genes_between_cases_with_CM-induced_pY-STAT3_DMFI_1_76_STAT3_Low_v_DMFI_1_76_STAT3_High_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070439
SOX4-29892750-EML-MOUSE-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06621
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5792
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.377604
A549_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163732
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54284
PMC5624885-41537_2017_33_MOESM1_ESM.xlsx-SIT1-SIT1_Top_500_differentially_expressed_genes_with_perturbations_in_CNTNAP2_carrier_NGN2-neurons_using_DESeq2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.88097
Lipoic acid_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0174075
A549_G007-LK_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175086
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21732
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-21	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
A549_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163436
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.016
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59403
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.66642
Perturb_13853_KO_RET_ERP126468	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE178267_2_v_0_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54556
Olanzapine_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0179289
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74116
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.167
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994879
A549_Tucidinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0289012
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42105
BT474	CCLE Cell Line Gene CNV Profiles	1.0	2.21093
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
U251MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17074
A549_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165937
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Biotin deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04977
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57607
Dendritic spine membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5446
TOMM40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08702
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04664
voltage-gated potassium channel activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_UNC1999_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130388
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	2.12823
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8672
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17465
Trametinib_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00772045
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0058
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.181
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09576
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-g-Classification_of_camel_SON_basal_genes_-_ion_channels_SON	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
NAD(P)-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
A549_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154541
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
pancreatic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51571
Perturb_124_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.95109
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05874
SAP30	ENCODE Transcription Factor Targets	1.0	null
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16744
Paranodal junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.967
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_MC1568_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182717
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
RELA-24523406-FIBROSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15071
PMC9528698-NIHMS1835045-supplement-Supp_table_53.xlsx-Sheet1-NC2_gene_symbol_DR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.064719
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_TG101209_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158144
A549_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203805
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67621
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4607
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07522
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3682
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83781
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLUFENAMIC ACID	DGIdb Drug Targets 2026	1.0	0.174118
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33038
USF2	ENCODE Transcription Factor Targets	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0389
A549_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118331
A549_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0302253
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28383
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0106
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180927
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediates	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68161
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87873
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCBP1_02_137	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63136
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.237992
Osimertinib (mesylate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0246401
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	2.65628
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33156
Perturb_13304_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.19858
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968899
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83057
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118343
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06009
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.189
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36784
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.0204
A549_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.009617
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09965
KYSE450	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14621
HSCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18679
TUFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11112
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
gated channel activity	GO Molecular Function Annotations 2015	1.0	null
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
specific learning disability	GWASdb SNP-Phenotype Associations	1.0	0.720196
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179414
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33362
lung	HPA Tissue Gene Expression Profiles	1.0	0.863053
CPK20	DGIdb Drug Targets 2026	1.0	3.30825
crig1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18387
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944684
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90424
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
age-related macular degeneration	GWASdb SNP-Phenotype Associations	1.0	2.14243
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10489
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
A2058	Achilles Cell Line Gene Essentiality Profiles	1.0	1.9702
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26153
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71023
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
SDHAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55541
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68169
KYSE150	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4857
channel	GeneRIF Biological Term Annotations	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.193
Sildenafil_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0223244
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922963
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03488
A549_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0217014
A549_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210736
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Potassium channel, calcium-activated, BK, alpha subunit	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.119678
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20662
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.36812
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LP1	CCLE Cell Line Gene CNV Profiles	1.0	2.10027
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24557
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03661
Exudative Age-Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
Dexamethasone_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0257869
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01216
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
voltage-gated cation channel activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847024
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943512
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Decitabine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0317857
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1809
17344918-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867638
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21366
Gastrocnemius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97445
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-545	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07427
capan-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.885862
A549_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214452
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41761
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
vincristine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0135585
artery disease	GWASdb SNP-Disease Associations	1.0	0.193829
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.40605
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-649	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RCM1	DepMap CRISPR Gene Dependency	1.0	6.72099
A549_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0231229
A549_Belinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0272481
K562_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192967
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08801
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
A549_Vandetanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0214289
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-590-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
phorbol 12-myristate 13-acetate	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	1.22553
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHOM1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.96833
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.230445
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36088
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898884
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828604
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PFI-1_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118244
A549_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142265
Scoliosis, Isolated, Susceptibility To, 3	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79004
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19272
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.3861
crossing	GeneRIF Biological Term Annotations	1.0	null
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.06106
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48394
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053836
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.461639
USP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19053
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170885
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30717
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92131
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.95558
Perturb_9215_KO_Rai1A_SRP260241	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55141
C-Reactive Protein	dbGAP Gene-Trait Associations	1.0	0.076146
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984353
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865629
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913215
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967076
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998379
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909848
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-8121-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-up-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17925
PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80098
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907316
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAFA-gene_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.245138
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.965766
CHD1	ENCODE Transcription Factor Targets	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76154
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0829
Arcuate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
A549_Veliparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171591
Human - Motor Cortex - Cluster - PVALB+ CDK20+ Layer 1-2 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized Myoclonic Seizures	DisGeNET Gene-Disease Associations	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6558
CDK8_knockdown_147_GSE32108	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.51996
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15118
NCIH520	DepMap CRISPR Gene Dependency	1.0	2.10742
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Temuterkib_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0153017
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999512
FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166646
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05436
abnormality of the macula	GWASdb SNP-Phenotype Associations	1.0	2.14243
Myofibrillar myopathy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67777
Arbutin_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0221853
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A549_Linifanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145411
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.41793
Dilated cardiomyopathy 1HH	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
A549_Luminespib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013653
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.30696
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_118_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44914
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14458
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19807
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.81827
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
A549_EED226_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0331062
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4353
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20834
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03837
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49933
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42971
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40993
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3829
HS834T	CCLE Cell Line Gene Expression Profiles	1.0	1.48594
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17033
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.51772
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10914
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.1899
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96592
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.0788
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163409
A549_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158911
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52837
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0433
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2019
CG-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12463
SNB75	DepMap CRISPR Gene Dependency	1.0	2.19337
GSE143692_0_v_1_trim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chorionic plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870396
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.775
PMC8755441-mmc3.xlsx-IRF1-UP-chip_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Temsirolimus_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154606
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55686
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
A549_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203459
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987799
A549_Tazemetostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.034448
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48715
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64924
Orlistat_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0243861
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27386
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12867
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29337
ES4	DepMap CRISPR Gene Dependency	1.0	4.52967
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122708,GSE123105_2_v_1_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.102913
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01696
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52181
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29502
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_NM-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30227
Human - Kidney - L2 - Parietal Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7261
A549_AT9283_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167225
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4433
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
adipose tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ascorbic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.12716
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892175
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-2426-SM-4AT4O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971745
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10917
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950164
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961941
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
STK11_knockout_278_GSE34866	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.21673
hsa-miR-4691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167505
Sodium	HMDB Metabolites of Enzymes	1.0	null
TP53_01_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60552
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172524
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851705
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124146
filter	GeneRIF Biological Term Annotations	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung cancer in ever smokers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7133
K562_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157983
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985621
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05986
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
ion channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TET1	ChEA Transcription Factor Targets	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19306
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
YY1	ChEA Transcription Factor Targets	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
A549_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0261713
A549_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171579
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	1.0	1.55459
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27528
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43029
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
NCI-H292	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Human - Kidney - L1 - Parietal Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06422
A549_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0303265
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45444
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909006
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.76655
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.4322
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.101
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23368
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47066
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14578
A549_Danusertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155104
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50048
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29063
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14966
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195255
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.049886
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03795
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867638
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Sucralose-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26378
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08699
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079698
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46104
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74617
A549_Ki16425_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016696
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917941
K562_Barasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156655
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03406
A549_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.02234
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01135
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
K562_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131234
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174628
D542MG	DepMap CRISPR Gene Dependency	1.0	5.4519
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
voltage-gated potassium channel complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0058
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151625
A549_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018631
A549_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018393
K562_Alvespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0361324
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847893
substrate-specific channel activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_17686_OE_HSD17B1_SRP366068	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34008
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89752
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	1.69835
potassium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975042
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26565
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32115
Ropivacaine (hydrochloride monohydrate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.01896
A549_CUDC-101_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190281
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40874
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12255
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34049
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55899
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2266
Perturb_119_KD_Fto_SRP314220	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0303199
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972199
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03021
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
cfpac-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10491
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
cation channel complex	GO Cellular Component Annotations 2015	1.0	null
A549_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147617
hsa-miR-362-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Atazanavir (sulfate)_SHP-77	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0107755
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12686
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21203
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19654
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15879
PMC3348545-NIHMS263168-supplement-3.pdf-62-ZNF648_ZNF648	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF780A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0951
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26656
kidney disease	GWASdb SNP-Disease Associations	1.0	0.975492
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Frontal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.225
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878622
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20178
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-2.62462
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0153
Pyridoxine_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0304446
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
A549_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149552
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.860141
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847796
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.017
Epineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
chloride-activated potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
COLO-783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE196117_6_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01944
NR1I2	ChEA Transcription Factor Targets	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903131
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.354834
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9206
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06489
outward rectifier potassium channel activity	GO Molecular Function Annotations 2025	1.0	null
PMC12645189-MRD-92-e70068-s005.pdf-0-ZBTB8A_ZBTB8A	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Hesperadin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0217998
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BEN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3500769-srep00875-s3.xls-PAX2-Time_1_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.34431
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5682
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
potassium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Azacitidine_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203539
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Tucidinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157522
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.25503
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21608
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21412
Hypsarrhythmia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683103
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4782
A549_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189296
High density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5504-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04999
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03584
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0226-SM-46MUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88989
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.28856
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11550_KD_HNRNPC_SRP366058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-UPK5-0126-SM-3GADM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13895
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52866
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.33749
hsa-miR-376b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.64039
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00909
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06752
A549_G007-LK_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153034
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232039
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	228.733
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15214
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42278
Cell body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85815
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16629_KO_Kir4.1_SRP133512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65404
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203752
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15457
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43745
Chlorine	HMDB Metabolites of Enzymes	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.62722
NCIH1876	CCLE Cell Line Gene Expression Profiles	1.0	2.15491
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858306
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.465486
SCH	DepMap CRISPR Gene Dependency	1.0	4.19324
PMC8569557-Table_2.XLSX-venn-Only_ZEB1_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.11843
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.39535
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94504
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29028
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04062
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-522	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902983
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	4.30293
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882756
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49963
EWS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84786
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97557
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Familial renal papillary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.092
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.0844
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.33936
A549_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210507
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.20709
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-0326-SM-3MJGV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825234
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.46617
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0258479
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44375
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96609
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3889
ion binding	GO Molecular Function Annotations 2015	1.0	null
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.169214
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02697
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01296
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190479
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
DDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83006
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72625
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.838
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	3.40793
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3031
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57727
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15227
A549_Fluorouracil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01276
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2279
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912946
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28566
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09858
A549_Rucaparib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137353
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917856
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF5_KO_GDS3509_553_mouse_ES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33789
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829364
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02409
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625061
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21692
Down Syndrome_Brain_GSE5390	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37451
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828054
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953626
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548u	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Droxinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166826
Calcium	HMDB Metabolites of Enzymes	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
A549_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159945
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-425	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
A549_Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0270817
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89856
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948892
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923408
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969371
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09932
atp binding	GO Molecular Function Annotations 2015	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57688
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10947
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48916
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838785
Perturb_4981_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9895
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03529
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.438
Spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.655
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Photic sneeze reflex	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8
GSE232564,GSE232566_3_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883147
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91489
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epileptic Encephalopathy	DisGeNET Gene-Disease Associations	1.0	null
Peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921981
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
A549_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192092
CHMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16847
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37918
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-L-Thyronine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32322
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.41717
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01119
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867815
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23322
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5831
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59779
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.52964
BA2+	DGIdb Drug Targets 2026	1.0	0.66165
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21619
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.775
iberiotoxin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.833776
transmembrane transporter complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066047
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07434
SK-MEL-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96125
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.52011
A549_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195943
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE224576_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NIFLUMIC ACID	DGIdb Drug Targets 2026	1.0	0.508961
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8S0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111247_0_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Selisistat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167605
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87027
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04346
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861999
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28549
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12526
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3726
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0339
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.976223
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5398
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10829214-13073_2024_1291_MOESM1_ESM.pdf-1-STAT5A_STAT5A	Rummagene Transcription Factor Associations 2026	1.0	null
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07952
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.09529
A549_SRT2104_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0117206
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27993
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81406
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38651
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.36479
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68672
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0271
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88247
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19662
GSE190177_1_v_0_sgpl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39314
Cinacalcet_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0214999
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13011
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00258
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.3739
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02183
Flutamide_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0193501
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18434
RAD21	ENCODE Transcription Factor Targets	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Methicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68095
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75394
A549_Ofloxacin_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120153
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
A549_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195226
hsa-miR-1202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1331
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dyslexia	GWASdb SNP-Phenotype Associations	1.0	0.720196
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29784
IMR32	CCLE Cell Line Gene Expression Profiles	1.0	1.67484
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9967
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.038
A549_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202335
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.845241
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Lapatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.029868
16778185-Table1	GeneSigDB Published Gene Signatures	1.0	null
UPCISCC111	DepMap CRISPR Gene Dependency	1.0	3.61774
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18411
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1087
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.79407
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996545
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.09173
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
learning disability	GWASdb SNP-Disease Associations	1.0	0.39208
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hippocampal mossy fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	1.67351
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
membrane part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05542
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844326
ion channel activity	GO Molecular Function Annotations 2015	1.0	null
A549_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0232949
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07303
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23583
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53983
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015045
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1242
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Human - Kidney - L3 - Parietal Epithelial	HuBMAP Azimuth Cell Type Annotations	1.0	null
A549_BMS-536924_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164538
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45134
voltage-gated channel activity	GO Molecular Function Annotations 2015	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05876
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923695
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.311891
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA2	ChEA Transcription Factor Targets	1.0	null
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37781
hsa-miR-3607-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
m8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32856
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_UNC1999_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221604
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22627
LPS6	DepMap CRISPR Gene Dependency	1.0	2.5889
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3961
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069102
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.935353
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral group of nuclei, left, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882798
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10881
GSE206400_1_v_0_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00817
Myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20O-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macular degeneration	GWASdb SNP-Disease Associations	1.0	2.19599
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Human - Motor Cortex - Subclass - Vip+ GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
passive transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
A549_Hesperadin_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164796
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070613
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845804
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884549
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7917
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.522421
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.02484
PMC10959942-41525_2024_411_MOESM1_ESM.pdf-13-CIC_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01418
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11135
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15161
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04732
ATF3	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1848
hsa-miR-641	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039857
NCIH838	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34425
hsa-miR-4517	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73603
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4829_KD_Rrp40_SRP150410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.68185
GSE233679_12_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.183599
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.105
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19158
Lennox-Gastaut syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.05
hsa-miR-4712-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03061
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28634
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165388
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Bosutinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113446
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49645
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.071
YMB-1-E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
coupling	GeneRIF Biological Term Annotations	1.0	null
A549_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124517
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.14942
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	4.10606
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870438
COLO818	CCLE Cell Line Gene Expression Profiles	-1.0	-2.26609
A549_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0259261
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50008
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69805
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10336
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.68634
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06288
PMC9377669-tx1c00392_si_002.xlsx-Magnesium_Cl-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
BACH1	ENCODE Transcription Factor Targets	1.0	null
Idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078808
hsa-miR-1911	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Anterior horn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874018
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26755
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
Granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
hsa-miR-4325	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Infancy electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.058
Mitochondrial ATP-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05371
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
Pars recta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
Clopidogrel_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0130779
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0043
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13062
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-TM_KO_vs_WT-Supplementary_Table_S2-2_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_TM_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03914
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OS252	DepMap CRISPR Gene Dependency	1.0	3.85708
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06721
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Rucaparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189436
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7957
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63847
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97437
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075041
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KQ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-0.843443
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14515
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.25121
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976297
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48058
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
potassium ion transport	GO Biological Process Annotations 2025	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844696
GATA3	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93891
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887062
POU5F1	ChEA Transcription Factor Targets	1.0	null
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14519
TCF4	ChEA Transcription Factor Targets	1.0	null
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
voltage-gated potassium channel complex	GO Cellular Component Annotations 2015	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.1104
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1526-SM-2XCFN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875371
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cocaine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.815
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Belumosudil (mesylate)_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0241589
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150187
NANOG	ENCODE Transcription Factor Targets	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4263	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972403
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.233273
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24325
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05637
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.169
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09291
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24929
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
panc-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539793
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3367-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30061
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
A549_Tozasertib_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013417
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0231905
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05471
GTEX-V955-1026-SM-4JBHO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825647
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TZ-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
A549_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138524
hsa-miR-548an	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6752
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2506
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52786
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT3_KO_GDS4817_416_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.841238
Bentamapimod_CHP-212	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0191016
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86819
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046119
NSUN5P2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45761
GSE233679_12_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
A549_ITSA-1_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153358
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11239
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metal ion transport	GO Biological Process Annotations 2015	1.0	null
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.75487
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.69322
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05817
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827981
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
p92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843889
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.89752
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-216b	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
YY1	ENCODE Transcription Factor Targets	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75286
A549_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0265519
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47521
Pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Danusertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.022065
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.118129
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180233
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07757
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67194
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52368
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6195
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.938777
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
Episodic ataxia type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5495
A549_SRT2104_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0297889
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02025
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26387
Perturb_4974_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71272
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.01814
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.24588
A549_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0273276
SOX2	ChEA Transcription Factor Targets	1.0	null
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66667
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7693
DMKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50657
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null