association	dataset	threshold value	standardized value
GT3TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.846669
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of movement	HPO Gene-Disease Associations	1.0	null
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91275
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_8290_KD_PRPF8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.01847
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
exchanges	GeneRIF Biological Term Annotations	1.0	null
Perturb_10075_KD_AQR_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.562
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.936109
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34454
CTPS2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42557763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27743
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29398
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22334
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40851
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE84462,GSE84762_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63504496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44354
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7352
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5657_KD_EF1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.944
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Perturb_2361_KD_YBX1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.88927
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073179
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55589
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K25876174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6288
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRE	Pathway Commons Protein-Protein Interactions	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.00684
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41673
PMC10189495-mmc10.xlsx-TCF4_wk1-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72157
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
identify	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47513
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
france	GeneRIF Biological Term Annotations	1.0	null
Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00396
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66231
Alzheimer 39 s disease and miRNA effects	WikiPathways Pathways 2024	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_7_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31918
BRD-K32930844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63969
velocity	GeneRIF Biological Term Annotations	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
BRD-K41044903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07316
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1998
Charcot-Marie-Tooth disease axonal type 2F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
JUND	ENCODE Transcription Factor Targets	1.0	null
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26849
Perturb_8289_KD_NONO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.7859
BRD-K57732605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13327
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883701
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_8755_KD_SON_SRP300475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
CI-1040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99443
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.223
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.06987
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22242
Intra-Golgi and retrograde Golgi-to-ER traffic	Reactome Pathways 2024	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15616
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833365
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57803
MSH2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55598155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08738
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0758
RCOR1	ChEA Transcription Factor Targets	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.54194
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
equilin-5255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16943_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.4739
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05062
BRD-K52424224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68319
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.688
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04904
BRD-K66413698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30031
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth disease type 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08834
biperiden-5279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.823139
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37297
microtubule associated complex	GO Cellular Component Annotations 2015	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.34715
Perturb_15901_KD_Jun_SRP361315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.76245
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11226445-41467_2024_49921_MOESM1_ESM.pdf-6-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69102
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26765
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.2428
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.299255
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965468
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.597
Charcot-Marie-Tooth disease axonal type 2CC	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPG2	Pathway Commons Protein-Protein Interactions	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92086
TRAK1	Pathway Commons Protein-Protein Interactions	1.0	null
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02647
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.71937
SLC25A13	Pathway Commons Protein-Protein Interactions	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.35271
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.884
BRD-K12342133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13767
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17004
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76677554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31097
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8196_KD_TIAL1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.56396
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	0.224946
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217541,GSE217543_3_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8450_KD_NPM1_SRP230777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12438
hydrochlorothiazide-1987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE153484_2_v_0_foxp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
MAP4K4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88195243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08284
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.999
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43799
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278251
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32472
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9027_KD_lncFAM_SRP377217	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.3994
Brain Lower Grade Glioma_LGG_TCGA-HT-7475-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884837
clozapine-5630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H64	GDSC Cell Line Gene Expression Profiles	1.0	1.70742
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	14.9745
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29105
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nabumetone-6487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.84636
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
zimeldine-2012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	ChEA Transcription Factor Targets	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33803
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00228
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72774
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.317456
BRD-K06392309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12146
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	0.951448
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.894918
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38506
binding	GO Molecular Function Annotations 2015	1.0	null
K562_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175566
lateral part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.061
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.41388
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.589
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-20a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
BRD-K09373762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00727
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25135
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.52987
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54317
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07504
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75074
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911757
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54507
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00436
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13263
interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076335
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
axonal	GeneRIF Biological Term Annotations	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.324201
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07481
LIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-379	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
LOX IMVI	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.36244
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1770	GDSC Cell Line Gene Expression Profiles	1.0	1.54753
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2647
Perturb_16944_OE_Snca_SRP280164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
charcotmarietooth	GeneRIF Biological Term Annotations	1.0	null
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02781
Perturb_15699_KD_PARP1_SRP280274	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.85095
Helam	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
GSE156923_0_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
microtubule-based movement	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZR	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43196
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.88
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24541
K562_Tucidinostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161534
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63019
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00654
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TOV112D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17448
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.706351
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_10134_KD_CTCFL_SRP108859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62886
BRD-K50710005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09994
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K33997327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19505
short-rib thoracic dysplasia 6 with or without polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.2279
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63024
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39566
HEY	DepMap CRISPR Gene Dependency	1.0	2.15561
SNU840	DepMap CRISPR Gene Dependency	1.0	2.09243
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65705
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4024
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
colon	HPA Tissue Protein Expression Profiles	-1.0	-0.794096
atropine oxide-1370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K63937112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05117
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.003
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859474
IKBKB	Pathway Commons Protein-Protein Interactions	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.315943
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.83574
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09518
Hereditary spastic paraplegia 5A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.451
Cancer of the testis_Testis_GSE1818	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.18975
methyldopa-5272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAPGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
etiocholanolone-3639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule associated complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17889
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
Perturb_8625_KO_Hnrnpd_SRP311571	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.5086
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE210476_9_v_8_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79801
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6861
HLA-DQA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dysautonomia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17425
transport	GO Biological Process Annotations 2015	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Perturb_9894_KD_STAU1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04594
LIVF001-028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89891
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13964
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3474
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061347
Perturb_10168_KO_TOP2A_SRP297586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.74311
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01698
Perturb_6891_KD_PIRIN_SRP375440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
E2F1	ChEA Transcription Factor Targets	1.0	null
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4678
BRD-K20110031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18937
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061162
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.291
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917145
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
TRAF3IP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-103a-3p	MiRTarBase microRNA Targets	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21177
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05162
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hereditary spastic paraplegia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.24804
Perturb_10048_KD_NONO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59816
TP63_NULL MUTATION_GDS1434_308_mouse_Skin at embryonic age E18.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12028
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
Perturb_12666_OE_GFP_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.3598
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.33291
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8282_KD_BCCIP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.51036
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4103
OARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01371
Lung adenocarcinoma_LUAD_TCGA-05-4427-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56847
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Urinary Urgency	DisGeNET Gene-Phenotype Associations	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41133627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55876
BRD-K15393664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2593
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33249
BRD-K39107553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04174
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68354
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06527
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.39079
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45414
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
BRD-K72255851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28131
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
neurodegenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	4.04661
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8194_KD_SAFB2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.82467
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.114624
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19395
RAB5C	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35896
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18183
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36133
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.588037
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.851584
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal breathing pattern	MPO Gene-Phenotype Associations	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.39206
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845728
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960306
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.014
pathology	GeneRIF Biological Term Annotations	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
Patellar Clonus	DisGeNET Gene-Phenotype Associations	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17675924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27619
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4390253__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	19.0045
BRD-K37203945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21356
hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
AGS_STOMACH	CCLE Cell Line Proteomics	1.0	2.57121
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30302
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0039
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44771
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RPL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37098
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.581758
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Perturb_11455_KD_GPRC5C_ERP135375	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.64536
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26225
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_8951_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4211
abnormality of extrapyramidal motor function	HPO Gene-Disease Associations	1.0	null
Babinski Reflex	DisGeNET Gene-Phenotype Associations	1.0	null
metronidazole-2003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-VN-1203-2004(H5N1)_Day4-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.10517
BRD-K45361857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23681
Perturb_16855_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55884
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
residue	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GB1	CCLE Cell Line Gene CNV Profiles	1.0	1.63154
BRD-K75981692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01776
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1684
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09728
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
BRD-K11893906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21322
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01099
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979176
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86105
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6042247-NIHMS966841-supplement-Sup_Table_2.xlsx-Gene_Sets-NEUROD2_NEUROD2	Rummagene Transcription Factor Associations 2026	1.0	null
AKT2_knockdown_44_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77714
depression	GWASdb SNP-Phenotype Associations	1.0	0.389907
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	19.5894
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11612
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-E2F6_OE_vs_EGFP_CTR_DE-gene_E2F6	Rummagene Transcription Factor Associations 2026	1.0	null
Myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.647
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55510118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04112
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.452
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36575
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
CSRNP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99747
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.14994
VMRC-LCD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15236
Perturb_8181_KD_XPO5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.09444
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01447
hsa-miR-107	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54717
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_176_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03204
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058189
BRD-K87146261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14337
Pontocerebellar hypoplasia type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
BZW1	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.746
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.0
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24416
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046735
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7557
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.125
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18122
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.31051
Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.879
H4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78086
FHF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.83178
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9539
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88314
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_IOX2_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181179
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46094
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
RRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36565
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OXSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18244
Cerebellar Purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58613
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.421
HDAC1	ENCODE Transcription Factor Targets	1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34187
BL8514 (CKAP2)	NURSA Protein Complexes	1.0	null
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
BRD-K18561719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14534
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.916957
Myelin membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9672
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	1.0	1.81333
YBX3_02_98	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60811
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20046
CRCGN015_MCF10A_48H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.033
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62886
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36625
hsa-miR-3647-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_2294_KD_DDX5_SRP139509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.35211
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
coagulation	GO Biological Process Annotations 2015	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39933
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23535
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05377
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052059
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.686368
charcot-marie-tooth disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.880653
RHO GTPase Effectors	Reactome Pathways 2024	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.94391
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20984
family	GeneRIF Biological Term Annotations	1.0	null
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998306
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861086
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07036
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29125789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39497
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.736
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0875
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26935
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041555
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05442
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
BRD-K84073439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91921
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941419
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66373
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.392
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97101
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.081372
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78026
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
Spinocerebellar ataxia type 29	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
SRY	ChEA Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00387
ZMPSTE24	Pathway Commons Protein-Protein Interactions	1.0	null
pneumoconiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11448
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dizocilpine-2232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NOMO1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K83586473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10069
cellular process	GO Biological Process Annotations 2015	1.0	null
mechanisms	GeneRIF Biological Term Annotations	1.0	null
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0929
RFX5	ENCODE Transcription Factor Targets	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847747
BRD-K68595406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05933
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gliding	GeneRIF Biological Term Annotations	1.0	null
SUDHL4	DepMap CRISPR Gene Dependency	1.0	3.03951
CAL-120	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Golgi-to-ER retrograde transport	Reactome Pathways 2024	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842255
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4985
BRD-K53354260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34683
dense core granule cytoskeletal transport	GO Biological Process Annotations 2023	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37835
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Downregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
A4FUK	CCLE Cell Line Gene CNV Profiles	1.0	1.40885
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Alzheimer disease	KEGG Pathways 2026	1.0	null
SNU213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35811
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Upper Limb Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.14098
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42982
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
RNF139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55035
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7892
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03528
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57387
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3660_KO_ZCCHC4_SRP189763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48527
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93479
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40726
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892733
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.904894
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.154
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K88313926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49153
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K29469525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24583
Perturb_16853_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.79282
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53308623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22885
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterograde dendritic transport	GO Biological Process Annotations 2025	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.923838
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03232
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97855
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897062
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03483
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071604
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872655
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_2_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.41829
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8603
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.933676
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53275
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Amyotrophic Lateral Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K61485947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2419
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_2-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
parkinsonism	HPO Gene-Disease Associations	1.0	null
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_16897_KI_Htt_SRP250656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.82607
establishment of localization	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20947
RUNX1	ChEA Transcription Factor Targets	1.0	null
large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.029927
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46517
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
disulfiram-1369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
Mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08174
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11501
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859522
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.47982
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906805
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.76063
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
PMC6545035-12943_2019_1031_MOESM7_ESM.xlsx-Sheet1-Supplementary_table_5_The_significant_reduced_genes_in_TET1_knockdown_cells_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16265
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.673
Effect of omega 3 PUFA on Huntington 39 s disease pathways	WikiPathways Pathways 2024	1.0	null
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.08788
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841717
large	GeneRIF Biological Term Annotations	1.0	null
EC-GI-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84205
Perturb_4134_KO_Trrap_SRP198540	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.58429
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05336
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23481
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.795
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.896
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958562
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80962
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40804
BRD-K69248736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42324
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841796
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8549
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pindolol-1392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
monastrol-596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SJSA1	DepMap CRISPR Gene Dependency	1.0	10.7521
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87939000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46215
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906074
CRCGN015_MCF10A_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22813
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K72356321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01977
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40316
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
anion binding	GO Molecular Function Annotations 2015	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7978
GSE122067_3_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL3837 (KDM5A)	NURSA Protein Complexes	1.0	null
Metabolism of proteins	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.7045
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
hsa-miR-936	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Cybrid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993778
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07133
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054521
Amyotrophic lateral sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.21549
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27457
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07737
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.877072
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.977067
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04698
Ionotropic glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-642a	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31864
GSE228181_4_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
DNAJA2	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10938
Thickening Of Pleura	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2275
AP3S1	Pathway Commons Protein-Protein Interactions	1.0	null
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53312
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hypomyelinating leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7971
T98G	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.63687
GSE154577_2_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0403_PANCREAS	CCLE Cell Line Proteomics	1.0	3.36343
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971815
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051908
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54144
GSE112763,GSE112767_4_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	1.0	1.37457
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24416
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912443
H3K79me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spastic	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4748	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1977
Salmonella infection	KEGG Pathways 2026	1.0	null
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
tubulin binding	GO Molecular Function Annotations 2023	1.0	null
optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.689092
Perturb_3010_KD_PAX2_SRP119912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53332
STX7	Pathway Commons Protein-Protein Interactions	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77891
Feeding Difficulties	DisGeNET Gene-Phenotype Associations	1.0	null
Charcot-Marie-Tooth disease type 4B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.502
16715129-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Autoimmune Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18149
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27913
paraplegia	GeneRIF Biological Term Annotations	1.0	null
Perturb_9694_KO_GPNMB_SRP382180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CGTHW1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61027
GSE160817_0_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
identification	GeneRIF Biological Term Annotations	1.0	null
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51082
cc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.286
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28258
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3692
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6152
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
Multisystem proteinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
BRD-K72872864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21887
MAPK14_knockout_14_GDS2693	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.3179
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6497_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64872
microtubule motor activity	GO Molecular Function Annotations 2015	1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K63145472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15354
CADM1_Deficiency_GDS2027_722_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
spastic gait	HPO Gene-Disease Associations	1.0	null
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.83562
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19588
NAP1L4	Pathway Commons Protein-Protein Interactions	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38347
atpase	GeneRIF Biological Term Annotations	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04703
urinary incontinence	HPO Gene-Disease Associations	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.23
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66823
Poisoning	CTD Gene-Disease Associations	1.0	1.05685
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
BRD-K62147342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3226
DNM1L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SJSA-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
combining	GeneRIF Biological Term Annotations	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34475
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04163
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurofibrillary tangle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.204
HCC827	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2998
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2518_KD_ZNF414_SRP269946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.82324
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1978
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17692
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8972
LUDLU1_LUNG	CCLE Cell Line Proteomics	1.0	2.21382
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16952
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.622
11739862-Table4	GeneSigDB Published Gene Signatures	1.0	null
Spastic Paraplegia	DisGeNET Gene-Disease Associations	1.0	null
MDA-MB-415	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
diloxanide-3399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retrograde neuronal dense core vesicle transport	GO Biological Process Annotations 2025	1.0	null
Henoch-Schoenlein Purpura	DisGeNET Gene-Disease Associations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
CAL-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51369
Lupus Vulgaris	DisGeNET Gene-Disease Associations	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1489
Endolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
ventropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21262
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1453
Perturb_531_KD_NKX22_SRP234742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90196
rosiglitazone_mus musculus_gpl1261_gse11343	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8091
asbestosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.451454
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84237
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE110268_2_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127104
Eye-retinal bipolar neuron	Tabula Sapiens Gene-Cell Associations	1.0	0.291195
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29931
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49143
BRD-K24929039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20358
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.583
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21186
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08406
hsa-miR-4667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
BRD-K08000110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22867
Hereditary sensory neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0509
BRD-K45142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23916
hsa-miR-4464	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.36748
hsa-miR-93	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5507
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.34
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.951629
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_171_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Hyaline inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
PRC1_BMI_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.30697
colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.078553
BRD-K59002219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60757
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33244
IST-SL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HLA-DQA2	Pathway Commons Protein-Protein Interactions	1.0	null
neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.129751
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2006
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15084
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08559
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.12811
BRD-K51972131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26444
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03785
ABCD1	Pathway Commons Protein-Protein Interactions	1.0	null
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922497
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.588672
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944284
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2855
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.946028
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0915
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95552
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04032
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
15980968-Table3b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02329
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01305
A-VN-1203-2004(H5N1)_Day4-10^3pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69739
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18987
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
hydrastinine-5494	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.08049
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03818
IDH2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K98944347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08049
BRD-K69817695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14495
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28172
Prion disease	KEGG Pathways 2026	1.0	null
sequencing	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
SPOAN syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
Autosomal dominant distal hereditary motor neuronopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_154_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A61522392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.80919
U2OS_BONE	CCLE Cell Line Proteomics	1.0	2.31043
hsa-miR-3617	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06075
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7949
BRD-K27302831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69362
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.4019
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.782
E.F.G complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
breast	HPA Tissue Protein Expression Profiles	-1.0	-1.14994
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14716
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.7841
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
german	GeneRIF Biological Term Annotations	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67835
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
docetaxel	CTD Gene-Chemical Interactions	1.0	null
KCTD12	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2342	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21004
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontotemporal Dementia	DisGeNET Gene-Disease Associations	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56402
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895252
KARPAS-45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65511
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867869
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.6
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.16
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prestwick-972-6511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.015203
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8232
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2868
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43818
DTNB	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.8108
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.929994
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061319
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11846
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.12608
BRD-K59386816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03306
cyanosis	MGI Mouse Phenotype Associations 2023	1.0	null
PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_3-Gene_Symbol_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91765
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34386
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53050301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34788
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17095
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4332150-msb0011-0775-sd13.xlsx-JUN-Prey_Gene_Symbol_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6233
anterograde dendritic transport of neurotransmitter receptor complex	GO Biological Process Annotations 2025	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33105
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22138
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
SLC7A5	Pathway Commons Protein-Protein Interactions	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999886
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68671
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
e2f1_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.382943
mammary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093244
BRD-K78195641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29326
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.956428
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831921
BRD-K49029187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73025
Perturb_8056_KD_IGF2BP1_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.68352
SUPHD1	CCLE Cell Line Gene Expression Profiles	1.0	2.47433
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
Cerebrotendinous xanthomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Perturb_11350_KD_NFAT1_SRP173011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.3979
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4873
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	3.21655
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_130_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886919
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	1.70653
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6397
astrocytes	BioGPS Cell Line Gene Expression Profiles	1.0	0.951448
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations	1.0	0.346786
neuron projection guidance	GO Biological Process Annotations 2015	1.0	null
BRD-K51779559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48324
ntera2	HPA Cell Line Gene Expression Profiles	1.0	0.903197
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.026
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42185
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13695
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69389
optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.434899
BRD-K44743425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61538
SKOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
Perturb_3243_KD_UCA1_SRP124072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.699
NESCAV syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
Talipes	DisGeNET Gene-Disease Associations	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26678
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.341
BRD-K16884266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08565
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	1.44639
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU5F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
SMN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834746
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8777
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44962
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_7_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE-70	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43526
impaired vibratory sensation	HPO Gene-Disease Associations	1.0	null
16424041-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16058
BRD-A40010674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70327
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45871
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.997
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47956
Centralspindlin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.57712
chlorzoxazone-2263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AFG3L2	Pathway Commons Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57077
Polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20912
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20844
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.626483
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10027
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.798
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27729
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09064
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ITSN1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31292
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959413
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	1.22577
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02554
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77643
orchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.499231
MHC class II antigen presentation	Reactome Pathways 2024	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.81495
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6589
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2378
SOX9	ChEA Transcription Factor Targets	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.497266
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899731
GATA2	ENCODE Transcription Factor Targets	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.69862
Charcot-Marie-Tooth disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.375
RNF2	ENCODE Transcription Factor Targets	1.0	null
neurite	GeneRIF Biological Term Annotations	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875002
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887696
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
arthritis, rheumatoid; rheumatoid arthritis	GAD Gene-Disease Associations	1.0	null
hsa-miR-4264	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
NOMO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03267
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_454_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6948
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13985
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35245
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07737
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08232
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
Perturb_10026_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68696
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.60652
population	GeneRIF Biological Term Annotations	1.0	null
BRD-K56107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58854
ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79714
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49708
TMA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3243
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31598
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02389
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74446
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
lidocaine-1999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-320-HSR	GDSC Cell Line Gene Expression Profiles	1.0	1.99862
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
zimeldine-1930	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07563
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57502201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00418
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30914
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1804
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38601
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33006
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05188
lorglumide-6456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3591-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	1.77467
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.502
CAL120	CCLE Cell Line Gene CNV Profiles	1.0	2.09602
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1477
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior horn cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3115
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6621
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12225
Myoclonus	DisGeNET Gene-Phenotype Associations	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
Charcot-Marie-Tooth disease type 2A1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45704
IPO8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K98201103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42559
Perturb_14627_KO_OGT_SRP146064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.82293
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
ATP1A3	Pathway Commons Protein-Protein Interactions	1.0	null
charcot-marie-tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.532314
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35716
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.938
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6369
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44346
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74783
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936494
NANOG	ChEA Transcription Factor Targets	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nfs25c3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
Cerebellum	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.901684
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044319
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90069
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27885385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09255
Bone inflammation disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
FOXA2	ChEA Transcription Factor Targets	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
peripheral neuropathy	HPO Gene-Disease Associations	1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.87837
Spastic paraplegia 10, autosomal dominant	CTD Gene-Disease Associations	1.0	2.88009
K562_Tazemetostat_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187515
Cytoplasmic stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04918
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19375
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04163
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954518
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81722
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A427	DepMap CRISPR Gene Dependency	1.0	2.83302
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Hemostasis	Reactome Pathways 2024	1.0	null
BRD-K58138729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23939
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
located	GeneRIF Biological Term Annotations	1.0	null
CAPN2	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye-muller cell	Tabula Sapiens Gene-Cell Associations	1.0	3.3885
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
oxolamine-3006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00118
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.00684
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70148
Perturb_12060_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6396
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Amyotrophic lateral sclerosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7031
immune system disease	GWASdb SNP-Disease Associations	1.0	0.091204
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.003
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42692
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.14865
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20478
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13905
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
BRD-K49292348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15863
Perturb_14004_OE_Kcnj2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.91011
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
ITGB2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41774018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69072
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30747
SMN-Sm protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.43783
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9237
BRD-K56357490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60816
Perturb_11691_OE_MYC_SRP253943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.41663
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
knee clonus	HPO Gene-Disease Associations	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
causing	GeneRIF Biological Term Annotations	1.0	null
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.033
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
SLC1A5	Pathway Commons Protein-Protein Interactions	1.0	null
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31243
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gitter cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68671
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5578
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36487
GSE81803,GSE81912_2_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2696
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14843
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DANG_PANCREAS	CCLE Cell Line Proteomics	1.0	2.41113
PMC12371027-42003_2025_8373_MOESM7_ESM.xlsx-Sheet_1-DYRK3_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30542
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03102
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_16_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2233
TMPO	Pathway Commons Protein-Protein Interactions	1.0	null
MDM2	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07829
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18267
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68397
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.927572
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2525
MDAMB436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98447
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58724
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3774
SW948	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2341
DOCK8	Pathway Commons Protein-Protein Interactions	1.0	null
k562	HPA Cell Line Gene Expression Profiles	1.0	0.850211
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73649
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.075
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78087
Perturb_1436_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54556
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.468401
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDC37	Pathway Commons Protein-Protein Interactions	1.0	null
atelectasis	MPO Gene-Phenotype Associations	1.0	null
cSARS Bat SRBD_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4634
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94867
motor	GeneRIF Biological Term Annotations	1.0	null
BRD-K84052780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45097
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.889021
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Nintedanib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164036
hsa-miR-4510	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086252
Perturb_9673_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.08893
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74766
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
SOX4_KD_GDS2193_37_human_adenoid cystic carcinoma derived cells ACC3	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55314
BRD-K73523821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1486
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
nextgeneration	GeneRIF Biological Term Annotations	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5255
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05843
Cytoplasmic ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.51
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Impaired Distal Vibration Sensation	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arthritis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
Urinary Incontinence	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_9_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
pirinixic acid-487	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
substance dependence	GWASdb SNP-Disease Associations	1.0	0.232384
G-292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38641
BRD-K46065636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49401
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21853
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11928
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67926
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0594
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978992
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21032
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92613860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50194
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Peptide hormone metabolism	Reactome Pathways 2024	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52511
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041164
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874608
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1453
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
Spastic Paraparetic Gait	DisGeNET Gene-Phenotype Associations	1.0	null
Peripheral Axonal Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.98152
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.913856
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00204
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45462
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31292
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Charcot-Marie-Tooth disease axonal type 2Z	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
Ankle Clonus	DisGeNET Gene-Phenotype Associations	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13712
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12379
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18367
Autosomal Dominant Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arthritis, Rheumatoid	dbGAP Gene-Trait Associations	1.0	0.654022
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20545
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61112
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.21
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053093
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08491
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2025	1.0	null
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.749
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5729
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4821
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59667
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48899005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71999
hsa-miR-4786-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82857
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927907
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930133
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01001
MOGS	Pathway Commons Protein-Protein Interactions	1.0	null
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
mania	GWASdb SNP-Phenotype Associations	1.0	0.708265
symptom	GeneRIF Biological Term Annotations	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85544
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84559
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCSTN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04577
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leg Muscle Stiffness	DisGeNET Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM129A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31842
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31175
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.132
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50328
BRD-K21671578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22162
BRD-K12396271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00045
BRD-K09875820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45618
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914784
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5006_KO_BACH1_SRP143680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.0369
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46259
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.309
microtubulebinding	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3919	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09774
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
azlocillin-2727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22273
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0804
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17714
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
Delayed Myelination	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal vesicle-mediated transport	MGI Mouse Phenotype Associations 2023	1.0	null
amiodarone-2434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.824013
BRD-K27525139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0852
rectum	HPA Tissue Protein Expression Profiles	1.0	1.00684
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.951448
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
systemic lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.238054
BRD-K21000135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15518
Perturb_14971_KD_Crebbp_SRP154933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11051
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45402
Talus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
Insulin processing	Reactome Pathways 2014	1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.285
single-organism intracellular transport	GO Biological Process Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01515
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PFKL	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6794_KD_PAF1_SRP060227	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.43474
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
KIF5A-related amyotrophic lateral sclerosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
BRD-K53548389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36364
Sensory dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.741
HLA-DPA1	Pathway Commons Protein-Protein Interactions	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053344
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20826
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887967
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32077
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34766
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17106
gamma-tubulin large complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62111
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
axonal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.069
mantle zone of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.061
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Arthritis, Rheumatoid	CTD Gene-Disease Associations	1.0	2.88009
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ankle clonus	HPO Gene-Disease Associations	1.0	null
COPI-dependent Golgi-to-ER retrograde traffic	Reactome Pathways 2024	1.0	null
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998306
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K38558166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28412
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13980_KD_Ago2_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.8718
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	1.22577
Autosomal dominant Emery-Dreifuss muscular dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7101
BRD-K05969019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22705
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Sickle Cell Anemia_Endothelial cell_GSE9877	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.162206
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40739
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cyanosis	IMPC Knockout Mouse Phenotypes	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.33754
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.83993
hsa-miR-519b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
GNAT3	Pathway Commons Protein-Protein Interactions	1.0	null
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06922
BRD-K56868780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34806
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999886
BRD-K57443386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33328
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25025
LPCAT1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.51079
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71221636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02738
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46167
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886141
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51966
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29398
Anterior spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
Chronic progressive external ophthalmoplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
OCILY10	CCLE Cell Line Gene Expression Profiles	1.0	1.5777
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8174_KD_PABPC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.68579
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36531
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39408
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56547
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25519
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12394
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE3C	Pathway Commons Protein-Protein Interactions	1.0	null
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113563
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2749
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92803674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36257
BRD-K09975619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33856
impaired vibration sensation in the lower limbs	HPO Gene-Disease Associations	1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
Membrane Trafficking	Reactome Pathways 2024	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1202
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4404
bone inflammation disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
transmission	GeneRIF Biological Term Annotations	1.0	null
BRD-K61681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1394
Perturb_337_KD_MYC_SRP301562	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.9876
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6673
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.246098
abnormality of the vertebral column	HPO Gene-Disease Associations	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02463
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61058
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
causes	GeneRIF Biological Term Annotations	1.0	null
Dendritic tree	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.073
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4297
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01872
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	2.8656
GSE201239_6_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	7.99095
SJRH30	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81423
microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829389
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.395
Charcot-Marie-Tooth disease axonal type 2H	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
extends	GeneRIF Biological Term Annotations	1.0	null
PCBD1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2492
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16566
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05775
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrosis Of Pleura	DisGeNET Gene-Disease Associations	1.0	null
anterograde dendritic transport of neurotransmitter receptor complex	GO Biological Process Annotations 2023	1.0	null
COLGALT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883184
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2342	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95145
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48997
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90168
Motor proteins	KEGG Pathways 2026	1.0	null
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K83139520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20981
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863273
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38526
TMEM185B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2256
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5404
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5958
PMC6078853-molce-41-7-695-suppl2.xlsx-Sheet1-Table_S1_Genes_exhibiting_two-fold_changes_in_expression_between_WT_and_CTCF_KO_otocyst_with_FDR_less_than_0_05_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13687_KD_ATG5_ERP127841	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.4837
Metabolism of proteins	Reactome Pathways 2024	1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2788
paraplegia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K32947579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19308
BRD-K18494310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6349
BRD-K48052985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05657
CLDN1_OE_GDS3510_393_human_CL1-5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
BRD-K25646425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42523
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08148
hsa-miR-3665	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43742
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PITPNB	Pathway Commons Protein-Protein Interactions	1.0	null
forms	GeneRIF Biological Term Annotations	1.0	null
Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57317
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50393
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02617
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.87948
Joubert syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
Diabetes Mellitus, Type 1	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959844
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hereditary sensory and autonomic neuropathy type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22357
Kinesins	Reactome Pathways 2024	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16698
SUIT2	CCLE Cell Line Gene CNV Profiles	1.0	1.58837
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2788
Postsynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38037
SFXN3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35555
OPLAH	Pathway Commons Protein-Protein Interactions	1.0	null
anterograde dendritic transport of neurotransmitter receptor complex	SynGO Synaptic Gene Annotations	1.0	null
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38047
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63407
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998306
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09364
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916453
PLAA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56149020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48613
ALAD	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28921
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01322
abnormal breathing pattern	MGI Mouse Phenotype Associations 2023	1.0	null
RAD21	ChEA Transcription Factor Targets	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.746798
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13959_KO_YAP1_SRP194022	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.7862
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50348
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23715
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04337
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lower limb muscle weakness	HPO Gene-Disease Associations	1.0	null
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myoclonus	ClinVar Gene-Phenotype Associations 2025	1.0	null
DU145	BioGPS Cell Line Gene Expression Profiles	1.0	0.951448
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73843
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96616
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931967
Brain disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8156_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.35097
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16397
Perturb_1752_KO_Runx1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
clofazimine-5277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21999
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	1.0	1.20193
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
USF2	ENCODE Transcription Factor Targets	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9129
microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CREBBP	ENCODE Transcription Factor Targets	1.0	null
BRD-K54694941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8543
Perturb_6393_KO_Ngr1_SRP098816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.68493
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09055
muscle weakness	HPO Gene-Disease Associations	1.0	null
BRD-K95035301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39594
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09659
BL1705 (PHB2)	NURSA Protein Complexes	1.0	null
bone disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DEL	CCLE Cell Line Gene Expression Profiles	1.0	1.72136
abnormal gas homeostasis	MPO Gene-Phenotype Associations	1.0	null
abnormal oxygen level	MPO Gene-Phenotype Associations	1.0	null
GSE189683_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973731
PFKM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2240_KO_L2hgdh_SRP093280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.62276
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6442
PCI38	DepMap CRISPR Gene Dependency	1.0	3.35266
Charcot-Marie-Tooth disease axonal type 2S	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.7649
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66079
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5004
Perturb_12576_KO_NOTCH1_SRP143456	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61157
U87	BioGPS Cell Line Gene Expression Profiles	1.0	1.61015
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59478
ADK	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K77965546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03368
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP1A1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9967_KD_SRPK2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.77518
t58-heart_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	2.4936
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79658624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1981
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Schinzel Giedion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891496
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33817
FAM49B	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amyotrophic lateral sclerosis type 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
ajmaline-2899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.27238
Myoclonic Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.00684
Signal Transduction	Reactome Pathways 2024	1.0	null
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
PRR4	Pathway Commons Protein-Protein Interactions	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
Perturb_5928_KD_MATR3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.18133
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52333
BRD-K39600742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46249
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4028
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83422
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62202
Wegener Granulomatosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.279
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09407
neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446862
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GMPS	Pathway Commons Protein-Protein Interactions	1.0	null
neural	GeneRIF Biological Term Annotations	1.0	null
Autosomal dominant distal hereditary motor neuronopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4359
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44596
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PSMD13	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95552
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4424
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
complicated	GeneRIF Biological Term Annotations	1.0	null
abnormality of the curvature of the vertebral column	HPO Gene-Disease Associations	1.0	null
BRD-K25757224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17264
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HSP90AB2P	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94294
molecular	GeneRIF Biological Term Annotations	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12869
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.98028
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963205
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Charcot-Marie-Tooth disease axonal type 2K	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21034
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8576
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67456
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45535
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.24715
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tubulin binding	GO Molecular Function Annotations 2015	1.0	null
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86045
hsa-miR-20b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67108
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
italian	GeneRIF Biological Term Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.046921
abnormality of the musculature of the limbs	HPO Gene-Disease Associations	1.0	null
Perturb_5192_KO_Nanog_SRP116119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.68032
SORBS1	Pathway Commons Protein-Protein Interactions	1.0	null
azathioprine-5262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20565
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50611
Cadmium Chloride	CTD Gene-Chemical Interactions	1.0	null
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
insight	GeneRIF Biological Term Annotations	1.0	null
IGR39	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04049
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89709
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951304
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
postsynaptic cytosol	SynGO Synaptic Gene Annotations	1.0	null
retrograde axonal transport	GO Biological Process Annotations 2025	1.0	null
BRD-K92144896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72431
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1775
Hereditary spastic paraplegia 77	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10102
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01816
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50017
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SURF4	Pathway Commons Protein-Protein Interactions	1.0	null
A388	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.90897
multiple	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069738
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41389
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13905
SNU216	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40383
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35205
hsa-miR-3529	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PCI15A	DepMap CRISPR Gene Dependency	1.0	2.15554
Perturb_3591_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.09374
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49443
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98385
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2006
KIF11	Pathway Commons Protein-Protein Interactions	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875836
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10908
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
Filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.117
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Progressive Pes Cavus	DisGeNET Gene-Phenotype Associations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940645
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
BRD-K52245873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4568
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	2.08847
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12982
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	4.06616
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36594
JAK2_activemutant_178_GSE44961	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.91468
MARCKS	Pathway Commons Protein-Protein Interactions	1.0	null
Amyotrophic lateral sclerosis	KEGG Pathways 2026	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931769
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.887314
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856301
Hereditary neuropathy with liability to pressure palsies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11294
Myelin sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
Pure Hereditary Spastic Paraplegia	DisGeNET Gene-Disease Associations	1.0	null
ChIP_POU5F1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059403
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
SC-583 (CREBBP)	NURSA Protein Complexes	1.0	null
ATP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A89354030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25888
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule binding	GO Molecular Function Annotations 2023	1.0	null
Rheumatoid arthritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE221955_3_v_2_igfbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47548
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555671
RHOC	Pathway Commons Protein-Protein Interactions	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
Inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
CRCGN015_MCF10A.TP53.M_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1924
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86527
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13472
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07332
visual pathway disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.428891
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05852
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6397
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
19605494-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV362	Achilles Cell Line Gene Essentiality Profiles	1.0	2.24399
TARS	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88314
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
Perturb_9963_KD_MTPAP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.4949
Rheumatoid arthritis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
USP15	Pathway Commons Protein-Protein Interactions	1.0	null
axo-dendritic protein transport	GO Biological Process Annotations 2025	1.0	null
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19308
intermediate part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19162
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2788
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	GWASdb SNP-Disease Associations	1.0	0.398392
VPS4B	Pathway Commons Protein-Protein Interactions	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.732
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10598
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12878
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290652
Perturb_8197_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.56985
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04393
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pirenperone-5274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38299
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21181
Perturb_6764_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.65903
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999763
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal joint morphology	HPO Gene-Disease Associations	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
ATP2B3	Pathway Commons Protein-Protein Interactions	1.0	null
susceptibility	GeneRIF Biological Term Annotations	1.0	null
Progressive supranuclear palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862163
BRD-K11342801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61728
hsa-miR-4728-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
Polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67091
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41046
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4036
iopanoic acid-6348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
N1E-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.568832
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18837
TSG101	Pathway Commons Protein-Protein Interactions	1.0	null
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37786
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
PANC0813	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.48403
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68671
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83569
BRD-K93316985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59363
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10473
pace of progression	HPO Gene-Disease Associations	1.0	null
ATP2A3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158197_6_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tranexamic acid-1401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dantrolene-3978	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COV434	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07451
K562_FLLL32_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167522
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.935226
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62762
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906074
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914829
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24906
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.622663
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IFI30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1964
Perturb_6838_KO_DOHH_SRP199981	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.18715
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855176
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31367
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43341
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
SW1783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.24192
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6969-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1187_KD_BCL6_SRP187038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.38337
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
D-423MG	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.541
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15084
spastic paraplegia 10, autosomal dominant	OMIM Gene-Disease Associations	1.0	null
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1937	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40344
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3269
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10535
Perturb_9882_KD_UTP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39244
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ischemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
mitochondrion	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K55662526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2509
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4419a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6196
clinical modifier	HPO Gene-Disease Associations	1.0	null
BRD-K48922193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80556
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20217
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08543
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
n1e-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576015
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	2.80463
PTK2B	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.36244
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBB4A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07775
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57969466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7788
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.84433
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05913
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28992
hsa-miR-106a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Central region of growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55426
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.688
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02928
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_19_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09017
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 26	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.997
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2568_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.4568
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.30147
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01301
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Charcot-Marie-Tooth disease type 1F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
Perturb_8173_KD_KHDRBS1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.65066
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26078
LCP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45414
steps	GeneRIF Biological Term Annotations	1.0	null
dominant	GeneRIF Biological Term Annotations	1.0	null
Spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56531
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.14976
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.35939
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960199
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Amyotrophic lateral sclerosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Perturb_2569_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.36101
intracellular transport	GO Biological Process Annotations 2015	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202323
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_123_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
Supramolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.406
diphenylpyraline-3640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31304
Autosomal dominant distal hereditary motor neuronopathy 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.737
Muscle Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
CAPZA1	Pathway Commons Protein-Protein Interactions	1.0	null
uncomplicated	GeneRIF Biological Term Annotations	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01082
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13969_KD_Elavl2/Elavl3/Elavl4_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.98439
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
SSRP1	Pathway Commons Protein-Protein Interactions	1.0	null
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Upper Limb Amyotrophy	DisGeNET Gene-Disease Associations	1.0	null
Lower Limb Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69396
MYC	ENCODE Transcription Factor Targets	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830715
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65955
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3184
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25268
PMC11373733-ABR-13-34_Suppl1.pdf-66-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046128
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97082
Perturb_14681_KD_NKX22_SRP072566	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.73614
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0844
PSMD6	Pathway Commons Protein-Protein Interactions	1.0	null
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.485289
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1467
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10096
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU423_LIVER	CCLE Cell Line Proteomics	1.0	2.96164
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90161
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940645
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-GSX1_GSX1	Rummagene Transcription Factor Associations 2026	1.0	null
ATXN10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7896
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21247
Lower Limb Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42404
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14042
Paresthesia	DisGeNET Gene-Phenotype Associations	1.0	null
RS411	Achilles Cell Line Gene Essentiality Profiles	1.0	2.34274
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
major	GeneRIF Biological Term Annotations	1.0	null
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35244
IKBIP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
atelectasis	MGI Mouse Phenotype Associations 2023	1.0	null
Oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.671
one	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05728
Hereditary spastic paraplegia 70	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0478
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_2543_KD_SNHG7_SRP179498	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.23056
Perturb_4721_KO_Setd5_SRP117752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.87594
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6351
Plasma membrane	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
FUOV1_OVARY	CCLE Cell Line Proteomics	1.0	5.57755
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Autosomal recessive cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IKBKG	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.131
BRD-K24640918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22611
when	GeneRIF Biological Term Annotations	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.26443
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0389
Spinal trigeminal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
EIF4A2	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal vesicle-mediated transport	MPO Gene-Phenotype Associations	1.0	null
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8533
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Basis pedunculi cerebri	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
nicotine_mus musculus_gpl1261_gse31004	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32565
Inherited Neuropathies	DisGeNET Gene-Disease Associations	1.0	null
POU5F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885773
racecadotril-1782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ADRBK2	Pathway Commons Protein-Protein Interactions	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_7587_KO_ALKBH5/FTO_SRP362871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.12159
MYL12A	Pathway Commons Protein-Protein Interactions	1.0	null
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.886
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	GeneRIF Biological Term Annotations	1.0	null
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
CLGN	Pathway Commons Protein-Protein Interactions	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00537
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.20136
Perturb_8097_KD_SUCLG1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.72326
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040769
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ciclosporin-602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01532
Perturb_17225_KD_SOX2_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93219
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33081
STAU1	Pathway Commons Protein-Protein Interactions	1.0	null
ANKRD27	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8582
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945478
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
Distal arthrogryposis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.878943
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882196
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31921933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10095
Perturb_69_KD_SMARCB1_SRP280151	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE210990,GSE211030_3_v_1_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940624
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39123
BRD-K74988798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19417
Perturb_5656_KD_CT_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.9348
ACTR1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15074
Pseudobulbar palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
neuron projection guidance	GO Biological Process Annotations 2023	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937147
Amyotrophic lateral sclerosis type 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90852
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17803_KO_ZNF675_SRP305529	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.09767
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-519c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5148
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25917
HMY1	DepMap CRISPR Gene Dependency	1.0	4.70179
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85611
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ASNA1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4653-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18776
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6476
MYO1D	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19383
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35912
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14248
Perturb_3885_KD_EIF2B5_SRP124930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.08592
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67392
ALDH1L2	Pathway Commons Protein-Protein Interactions	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4277
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KA2	Pathway Commons Protein-Protein Interactions	1.0	null
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.73532
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2887
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.21076
ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LN428	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.33382
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041917
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996772
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46214
sensory peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.284728
K562_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218106
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuromuscular disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26518
SLC25A12	Pathway Commons Protein-Protein Interactions	1.0	null
GSE255410,GSE255416_1_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
Hereditary spastic paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.313
REST	ChEA Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0074
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8819
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3733
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17098
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230931
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966014
Spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.425
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88252
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01783
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07096
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919779
provide	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SCYL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35521
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64914
Perturb_9061_KD_NANOG_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.9363
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07781
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Immune System	Reactome Pathways 2014	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08505
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PAX6_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
confers	GeneRIF Biological Term Annotations	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
microtubulebound	GeneRIF Biological Term Annotations	1.0	null
ARHGAP4	Pathway Commons Protein-Protein Interactions	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36098
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.45009
Perturb_14705_KO_Col1a1_SRP198671	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.80113
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171286
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.7614
AP2A2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29538
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIF5C	Pathway Commons Protein-Protein Interactions	1.0	null
anterograde axonal protein transport	GO Biological Process Annotations 2025	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMD7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
BRD-K78902613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03367
Perturb_5273_KO_Rif1_SRP348198	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.43849
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25118
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56807
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78557
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45759
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K68916730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66436
abnormal peripheral nervous system morphology	HPO Gene-Disease Associations	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12676
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atp-dependent microtubule motor activity, plus-end-directed	GO Molecular Function Annotations 2015	1.0	null
AARS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K47886441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0661
POLD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.042
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81082552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24433
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63296
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8350019-mmc3.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14197
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNAL	Pathway Commons Protein-Protein Interactions	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2393
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_19_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86637
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11449
15297395-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Chorea	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-A80010944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0416
biological_process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
BRD-K10189430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86602
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01103
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2734_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.36635
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Peptide hormone metabolism	Reactome Pathways 2014	1.0	null
BRD-K30217326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.15358
BRD-K90879242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0502
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48773
BRD-K42296822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09311
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
paraplegias	GeneRIF Biological Term Annotations	1.0	null
SMN2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Frontoparietal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
GNA13	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51976
COLO-678	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Myoclonus	DisGeNET Gene-Disease Associations	1.0	null
Epilepsy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
trichostatin A-2208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
celiac disease	GWASdb SNP-Disease Associations	1.0	1.40141
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11457
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899578
regulate	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07861
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897835
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Astral microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hyperreflexia	HPO Gene-Disease Associations	1.0	null
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45414
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
IDH1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826352
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.003
missense	GeneRIF Biological Term Annotations	1.0	null
Oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25889
BL1485 (MLST8)	NURSA Protein Complexes	1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03954
rimexolone-5092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48772
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8731
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.259969
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.914284
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K56870337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34018
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99103
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8185471-mmc4.xlsx-D2-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_2_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Ptosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48659
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kinesins	Reactome Pathways 2014	1.0	null
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6433
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73595
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48474
Perturb_6766_KD_PAF1_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.93833
REC1	CCLE Cell Line Gene CNV Profiles	1.0	1.47949
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_8287_KD_DDX55_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.86105
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.145
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.910097
ATAD3C	Pathway Commons Protein-Protein Interactions	1.0	null
MHC class II antigen presentation	Reactome Pathways 2014	1.0	null
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Frontotemporal dementia and/or amyotrophic lateral sclerosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.537731
vesicular	GeneRIF Biological Term Annotations	1.0	null
CDK8_knockdown_63_GSE19199	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.63968
Axonal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.263
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51665
hsa-miR-1301	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.18357
CAP1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998306
CHD4	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vesicle-mediated transport	Reactome Pathways 2024	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883701
cytosol	GO Cellular Component Annotations 2015	1.0	null
BRD-A94698726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34024
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.621951
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28921
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77875023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18567
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17622
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063627
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26518
CBX3	ENCODE Transcription Factor Targets	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0818
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.53703
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30516
amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.391885
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
only	GeneRIF Biological Term Annotations	1.0	null
BRD-K47762331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09719
antigen processing and presentation of exogenous peptide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K58930048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00322
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948126
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
retrograde neuronal dense core vesicle transport	GO Biological Process Annotations 2023	1.0	null
Distal myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
BRD-K39438085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12802
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953563
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40128
oxolinic acid-2266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10566
BRD-K54506283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73814
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933733
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2224
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976381
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.085714
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
BRD-K55852567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81503
pinacidil-6356	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE217541,GSE217543_0_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule	GO Cellular Component Annotations 2023	1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08902
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1758
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.006325
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	3.57945
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83569
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82612
Lung adenocarcinoma_LUAD_TCGA-50-5946-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
BCPAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
kinesin	GeneRIF Biological Term Annotations	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.057442
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.881085
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
BRD-K85843964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18162
BRD-K53816426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.005
BRD-K85044233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3609
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22692
BRD-K66013406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02121
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6465
PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17087
review	GeneRIF Biological Term Annotations	1.0	null
peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.661594
Perturb_8172_KD_ILF3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.393
BRD-K27354087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50852
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01656
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44637
BRD-K15174326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05581
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01962
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057386
Perturb_2567_KD_HMGCR_SRP216293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.98948
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63052
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7004
BRD-K46085646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50825
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48386
HLA-DQB2	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868425
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary spastic paraplegia 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
BRD-A52729710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30697
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BL2780 (SUV39H1)	NURSA Protein Complexes	1.0	null
movement	GeneRIF Biological Term Annotations	1.0	null
BRD-K79551673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62093
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08948
BRD-K81322049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27787
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850772
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979113
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia 37	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.921
Sensory peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
Hereditary spastic paraplegia 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
axo-dendritic protein transport	GO Biological Process Annotations 2023	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843323
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4302	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
docosahexaenoic acid ethyl ester-664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86287
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.34459
GTEX-Q2AH-1726-SM-3NB2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1097
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25649
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6397
LPCAT2	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053744
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.97015
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40866
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.951448
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1629
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849805
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17227
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08842
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FDFT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.98144
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993778
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0107
CYFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32079
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6826
Neurodegenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30833
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Autonomic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
Muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.024
G-292-Clone-A141B1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39258
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950404
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.096874
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1717
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12057_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.0105
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.11843
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLC2	NURSA Protein-Protein Interactions	1.0	0.128074
LPS27	DepMap CRISPR Gene Dependency	1.0	10.2715
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83569
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
plus-end kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
confirms	GeneRIF Biological Term Annotations	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	3.64529
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.891
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SLC3A2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10135_KD_RNPA1_SRP141197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.01431
ATP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17218_KD_OCT4_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
distal sensory impairment	HPO Gene-Disease Associations	1.0	null
Charcot-Marie-Tooth disease type 2E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839016
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09792
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13184
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2479
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062025
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11513
bsc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53693
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Developmental Stagnation	DisGeNET Gene-Phenotype Associations	1.0	null
MDM2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14503
BRD-K74855272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95867
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954793
BRD-K45732260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17594
antigen processing and presentation of peptide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48988
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A30758703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19219
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.427
KLC2-nKHC-uKHC kinesin complex	CORUM Protein Complexes	1.0	null
PMC4390253__F1	PFOCR Pathway Figure Associations 2024	1.0	null
SW962	GDSC Cell Line Gene Expression Profiles	1.0	2.00133
Hereditary spastic paraplegia 45	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66870022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93974
BRD-K43979194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29133
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857959
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
kinesins	GeneRIF Biological Term Annotations	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872587
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33401
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.886845
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57489406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06967
ATP1A4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30297
Lung adenocarcinoma_LUAD_TCGA-99-7458-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14761_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.50504
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03529
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
Inflammation	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932207
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiomyoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
motor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850496
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02925
Charcot-Marie-Tooth disease X-linked dominant 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.575772
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	2.20996
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6576
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.502
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-GSX1_GSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72367
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
Charcot-Marie-Tooth disease intermediate type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
BRD-K44403120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96424
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.00684
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS422	CCLE Cell Line Gene Expression Profiles	1.0	2.06003
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895478
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.502
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00681
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60386
BRD-K51140037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67269
hemostasis	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26035
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75425
protein complex	GO Cellular Component Annotations 2015	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
cytoskeleton-dependent intracellular transport	GO Biological Process Annotations 2015	1.0	null
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18048
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.204499
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.25438
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16182
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11213
Perturb_2615_Mut_SF3B1_SRP249914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.04526
BRD-K39561340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57172
GSE119345_2_v_4_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
H357	DepMap CRISPR Gene Dependency	1.0	2.05842
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
Myelin sheath adaxonal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03893
sclerosis	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.16112
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9511
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00623
Xanthomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.05719
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hereditary spastic paraplegia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Perturb_8180_KD_STIP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.10755
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01359
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
TOMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2653
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25669
K562_YM155_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143546
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.192004
Perturb_13008_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13173
Hereditary spastic paraplegia 39	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.027
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37005
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03535
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27635561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08389
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MEL-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.755499
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29939
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31611
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPP_KO_GSE40207_380_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
M6PR	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58212
BRD-K52225720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64371
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.18259
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38205
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01546
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50146
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9184
CRCGN012_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81115
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3791
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.63205
Perturb_11348_KD_NFAT1_SRP173011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.9249
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68576
PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33268
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K90827020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30535
BRD-K40241022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64887
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.528162
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00657
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.404629
BRD-K53488338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09342
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spastic cerebral palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.427765
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047262
Motor neuron disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Hereditary spastic paraplegia 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.513
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28339
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.6109
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
phenotype	GeneRIF Biological Term Annotations	1.0	null
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40361
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.463527
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954793
Lung adenocarcinoma_LUAD_TCGA-44-2657-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GNAO1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17801_KO_FOXB1_SRP179665	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.01809
arthritis, rheumatoid;	GAD Gene-Disease Associations	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044572
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9651
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.2428
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.161464
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S100A9	Pathway Commons Protein-Protein Interactions	1.0	null
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.934
ANGMCSS	DepMap CRISPR Gene Dependency	1.0	3.93341
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
propantheline bromide-3352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMS10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32771
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87047
Signaling by Rho GTPases	Reactome Pathways 2024	1.0	null
AP3B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38404
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blood Protein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.575495
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07618
Pyramidal Sign	DisGeNET Gene-Phenotype Associations	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35737
BRD-K30797133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96031
brompheniramine-4131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K08036779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.80269
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.013
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6036
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13256
BRD-K44648112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55571
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13909_KO_QPRT_SRP143388	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.87804
PPP2R2A	Pathway Commons Protein-Protein Interactions	1.0	null
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17453
Perturb_3845_KD_lncRNAAF339830_SRP161584	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.99798
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21177
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56668
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75503
BRD-K46015322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08476
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL268 (MCM8)	NURSA Protein Complexes	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921974
Edema	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_10211_KD_TP63_SRP353945	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.3372
KLC1-nKHC-uKHC kinesin complex	CORUM Protein Complexes	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064304
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29565
TPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29294
MYL6B	Pathway Commons Protein-Protein Interactions	1.0	null
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27027
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.56284
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842552
Perturb_17800_KO_FOXB1_SRP179665	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.32414
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4311
Perturb_12516_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.3574
Perturb_14589_KI_LAMC2_ERP136718	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.31315
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skein-like inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31331
ERR2 (ESRRB)	MotifMap Predicted Transcription Factor Targets	1.0	null
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.950332
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.870885
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00498
SRP68	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00261
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.992
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29568
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_493_KO_RN7SK_SRP367813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.9281
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901079
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15257
Bunina body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
CLPP_KO_GSE40207_396_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25559116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30827
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.673
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35321
BRD-K47951859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98445
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917129
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.14994
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
impairment	GeneRIF Biological Term Annotations	1.0	null
K562_A-366_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165517
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HLA-A	Pathway Commons Protein-Protein Interactions	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11718
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9238
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5631-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.812342
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.554
Perturb_10058_KD_UCHL5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76544
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome Pathways 2024	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNE3	Pathway Commons Protein-Protein Interactions	1.0	null
RSV-A2_24Hour-KO_RSV_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.48117
heavy	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69164
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92901
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Friedreich ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79619
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90122
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98083
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19621087-Table1e	GeneSigDB Published Gene Signatures	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
K562	CCLE Cell Line Gene Expression Profiles	1.0	2.7735
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.07376
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58779
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
SUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.4465
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0261
Lateral loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
nucleotide-excision repair factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
PMC2742312-1479-7364-3-3-221-S3.PDF-259-DDIT3_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.00684
axonogenesis	GO Biological Process Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.35271
Acute Myeloid Leukemia_LAML_TCGA-AB-2996-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	1.40141
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.38071
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.01198
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20621
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36655
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DHCR7	Pathway Commons Protein-Protein Interactions	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957961
Perturb_10116_KD_PAPOLA_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.90329
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57077
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06611347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.492
OGDHL	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8595_KO_Scn1a_SRP311872	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.85654
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10765
Perturb_8764_KD_SLIT2_SRP158939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.38973
ZC3HAV1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14994
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9189
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840672
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843763
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19521
HLA-DRB4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAND1	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01618
BRD-K46715415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09518
unresponsive to tactile stimuli	IMPC Knockout Mouse Phenotypes	1.0	null
CCK81_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.0939
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
IGROV1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.59373
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28518
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53529
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26717
CRCGN011_HEPG2_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0581
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5146
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09061
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20246
GSE157262,GSE157268_3_v_0_ythdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bilateral parasagittal parieto-occipital polymicrogyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13032
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42238
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226233_0_v_1_pccb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Pallor	DisGeNET Gene-Phenotype Associations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.81
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21990363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44767
PMC6287006__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997151
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.520206
hsa-miR-3140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.32813
DHCR24	Pathway Commons Protein-Protein Interactions	1.0	null
ATAD1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11175
CP-944629-7497	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hereditary spastic paraplegia 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.318
H3K36me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adaptive Immune System	Reactome Pathways 2024	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050596
lower limb spasticity	HPO Gene-Disease Associations	1.0	null
GSE201239_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4524	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832282
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51348
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.523
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990485
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925125
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
hereditary	GeneRIF Biological Term Annotations	1.0	null
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31593
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41957
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51566
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16636_OE_Chmp2b_SRP238748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76491
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53452
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-gene_name_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
nKHC-KLC1-KLC2 kinesin complex	CORUM Protein Complexes	1.0	null
Omega speckle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Charcot-Marie-Tooth Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2114	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.588832
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of vesicle localization	GO Biological Process Annotations 2023	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.70884
CRCGN017_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18772
Perturb_13968_KD_Ago2_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06417
BRD-K05462252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15296
Perturb_9782_KD_Esrrb_SRP321923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.96795
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.171548
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77836
TIM22 mitochondrial import inner membrane insertion complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.51
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0276
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.28515
Perturb_2455_KD_ZNF213_SRP243455	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.68118
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.47796
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09457
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
RNH1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48237
hsa-miR-1914	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HLA-DRB5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75742
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25592
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
variable	GeneRIF Biological Term Annotations	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0579
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15695_OE_PARG_SRP337621	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.93358
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9165_KD_circCAMSAP1_SRP366297	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.77768
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32226
LU-139	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GSE84678,GSE93902_3_v_0_bcl11b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
SART3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64317863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80187
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051968
including	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11775
functional abnormality of the bladder	HPO Gene-Disease Associations	1.0	null
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the ankles	HPO Gene-Disease Associations	1.0	null
ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.299197
CD9	Pathway Commons Protein-Protein Interactions	1.0	null
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.912859
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
Myosin II filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
Perturb_8591_KO_Fto_SRP097869	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.501881
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_9972_KD_BCLAF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.06401
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1602
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mast syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.930055
ARHGEF7	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15080_KD_Chd8_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.0638
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847681
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Factors involved in megakaryocyte development and platelet production	Reactome Pathways 2014	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38042
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3353
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
TBP	ChEA Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.886
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01107
BRD-K41033343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16692
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08625
BRD-K46607226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53298
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K34451734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30404
Perturb_16641_KO_Gaa_SRP277449	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.3937
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18122
SNPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12224
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epilepsy	GeneRIF Biological Term Annotations	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Perturb_9852_KD_LUC7L_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.70814
Amyotrophic lateral sclerosis type 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
HLA-DRA	Pathway Commons Protein-Protein Interactions	1.0	null
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69673
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18181
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6206
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-1926-SM-3GIL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980296
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03535
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93722
BRD-K45516283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09473
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00144
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.74789
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.53844
Amyotrophic lateral sclerosis type 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39744
LPS6	DepMap CRISPR Gene Dependency	1.0	9.71529
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.920547
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045181
deferoxamine-3936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8973
Perturb_9672_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.53343
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15903
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4797-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Centrum semiovale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053575
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2389_KD_NSD3_SRP267458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.78895
neck	GeneRIF Biological Term Annotations	1.0	null
Perturb_13886_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.1507
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4527
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.534
t58-heart_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.04925
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RH18	CCLE Cell Line Gene CNV Profiles	1.0	1.76221
CFPAC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7451
hsa-miR-4724-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3471
KIAA0196	Pathway Commons Protein-Protein Interactions	1.0	null
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
timolol-5280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
all	GeneRIF Biological Term Annotations	1.0	null
asbestosis	GeneRIF Biological Term Annotations	1.0	null
NCIH596	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34905
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904641
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54988
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3312
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26351
Spastic/Hyperactive Bladder	DisGeNET Gene-Phenotype Associations	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983381
YY1	ENCODE Transcription Factor Targets	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.3689
PMC3470785-NIHMS377161-supplement-3.pdf-104-C11orf9_MYRF	Rummagene Transcription Factor Associations 2026	1.0	null
CCT5	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscular Fasciculation	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5884
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01889
rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TSPYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39694
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00524
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2981
Progressive muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.549
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860733
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.866034
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
site	GeneRIF Biological Term Annotations	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6343
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26994
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.997
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854776
BRD-K45282594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53227
Hereditary spastic paraplegia 78	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Amyotrophic lateral sclerosis type 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4556
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990724
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32973
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07925
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
progressive disorder	HPO Gene-Disease Associations	1.0	null
XRCC4	Pathway Commons Protein-Protein Interactions	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
BRD-K89574562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.18309
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.647721
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71274
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K47160864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3473
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18826
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.268845
CHD1	ENCODE Transcription Factor Targets	1.0	null
Nerve Degeneration	HuGE Navigator Gene-Phenotype Associations	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
CAL120	DepMap CRISPR Gene Dependency	1.0	6.69442
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993778
Early myoclonic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
hypertonia	HPO Gene-Disease Associations	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69209
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_7280_KO_CASC3_ERP118046	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.5615
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35876
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88314
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24407
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_3_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.02879
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40093
BRD-K76713298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32732
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972887
Central Visual Impairment	DisGeNET Gene-Disease Associations	1.0	null
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15456
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Autosomal dominant distal hereditary motor neuronopathy 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00681
BRD-K63263229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49601
BRD-K54123736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15599
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51498
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42373
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.138
immune system process	GO Biological Process Annotations 2015	1.0	null
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-1.14994
Perturb_4211_KO_Fmr1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.57088
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.271
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.932998
SUN2	Pathway Commons Protein-Protein Interactions	1.0	null
metformin-61	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77375
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
anterograde dendritic transport	GO Biological Process Annotations 2023	1.0	null
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A02612852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08546
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
anterograde axonal transport	GO Biological Process Annotations 2025	1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.166
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.18816
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.73423
K562_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202239
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65561
hsa-miR-17	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46108
hsa-miR-657	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GSE199606_5_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.263
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30965
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.21695
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18305
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01082
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.67984
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2285
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69885
AGPAT5	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10002_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.31969
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897027
metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862458
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43139
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
change	GeneRIF Biological Term Annotations	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91152
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088415
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_11_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHI3L1	Pathway Commons Protein-Protein Interactions	1.0	null
multiple sclerosis	GAD Gene-Disease Associations	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05736
Lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06988
Oligospermia	CTD Gene-Disease Associations	1.0	1.28518
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00118
arthritis, juvenile rheumatoid; arthritis, rheumatoid; chronic childhood arthritis; rheumatoid arthritis	GAD Gene-Disease Associations	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876288
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29741
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5556
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906074
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
merbromin-3700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SAR1B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MYO1E	Pathway Commons Protein-Protein Interactions	1.0	null
CARD9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.642715
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61522
NUP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24323
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	GeneRIF Biological Term Annotations	1.0	null
Huntington disease	KEGG Pathways 2026	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14721
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2548
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48988
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01464
FAM105A	Pathway Commons Protein-Protein Interactions	1.0	null
NB120-3333 (PSME3)	NURSA Protein Complexes	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03854
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obtained	GeneRIF Biological Term Annotations	1.0	null
PMC8350019-mmc3.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral white matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.869
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08302
kinesin complex	GO Cellular Component Annotations 2015	1.0	null
BRD-K41939184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22573
phenotypes	GeneRIF Biological Term Annotations	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6671
Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.655024
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34721572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43939
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	1.79189
BRD-K83567669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03045
Microtubule end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.897
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04107
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01411
Anterior horn cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6175
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20748
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08054
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.296
antigen processing and presentation of exogenous antigen	GO Biological Process Annotations 2015	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.20327
BRD-K57756744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2806
Alzheimer 39 s disease	WikiPathways Pathways 2024	1.0	null
non-myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
Perturb_2211_OE_Trp53|Pdgfra_SRP332087	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99269
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.958154
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.9214
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM26	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_3987_KO_Actb_SRP195587	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951304
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68671
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
EWS502	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90765
Hereditary spastic paraplegia 35	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.088
CADM1_KO_GDS2026_301_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881861
CRCGN017_MCF10A.TP53.M_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98986
membrane	GO Cellular Component Annotations 2015	1.0	null
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.2842
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82625
TCF3	ChEA Transcription Factor Targets	1.0	null
Perturb_9927_KD_SRSF5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.19254
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25621
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
stalk	GeneRIF Biological Term Annotations	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16308
PMC11046693-pnas.2320938121.sapp.pdf-24-ISL1_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5640_KD_JQ1_SRP142503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.89896
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13641
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50271780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79017
BRD-K86158100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04988
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.923
ATL3	Pathway Commons Protein-Protein Interactions	1.0	null
APOL2	Pathway Commons Protein-Protein Interactions	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
BZW2	Pathway Commons Protein-Protein Interactions	1.0	null
did	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70436
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.46847
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16502
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974097
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
ATP4A	Pathway Commons Protein-Protein Interactions	1.0	null
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20052
Prostate adenocarcinoma_PRAD_TCGA-CH-5754-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060221
Perturb_3841_KD_NFE2L2_ERP105460	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.48027
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8375
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8417
NCIN87_STOMACH	CCLE Cell Line Proteomics	1.0	2.76848
Microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.701
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29754
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60359
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUL4A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3785_KD_TOX4_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.356
Intracellular signaling and cell migration supercomplex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48938
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93154
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EB-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
TRIM28	ChEA Transcription Factor Targets	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7289
synaptic vesicle transport	GO Biological Process Annotations 2023	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
potentially	GeneRIF Biological Term Annotations	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41758
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19805
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenosine Triphosphate	CTD Gene-Chemical Interactions	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847899
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76105
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_8_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	3.68561
single	GeneRIF Biological Term Annotations	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_111_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73808079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21575
Perturb_12515_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.32675
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2072
BRD-K13257316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5776
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47745
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30262
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24114
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33271
BRD-K35308744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8298
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Brain Lower Grade Glioma_LGG_TCGA-HT-7877-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04403
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11866
BRD-K75807319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84883
A-VN-1203-2004(H5N1)_Day4-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.02119
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYNCRIP_OE_GDS3575_87_mouse_C57BL/6 mice	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
argues	GeneRIF Biological Term Annotations	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25094
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.285
Autosomal dominant distal hereditary motor neuronopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50831
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24994
isocorydine-1787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10923439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38496
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955765
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
mantle zone of VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20942
MX1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19613760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0833
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980716
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_16642_OE_Chmp2b_SRP238748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57032
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46529
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
Insulin processing	Reactome Pathways 2024	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.90023
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.783252
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0921
Perturb_3632_KO_HDAC8_SRP355605	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.79872
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.721
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65737
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.93269
spasticity	HPO Gene-Disease Associations	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2226
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68875
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15352_KO_DND1_SRP319950	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.5802
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962817
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Amyotrophic lateral sclerosis type 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.0204
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51295743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91085
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.927932
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883701
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.597276
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8527
Perturb_17807_KO_ZNF675_SRP304971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.09767
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.626
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19675
phthalylsulfathiazole-3371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.063989
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20389
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.68208
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44969
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH18A1	Pathway Commons Protein-Protein Interactions	1.0	null
ranging	GeneRIF Biological Term Annotations	1.0	null
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.49932
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
Leukodystrophy	DisGeNET Gene-Disease Associations	1.0	null
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
F36P	CCLE Cell Line Gene Expression Profiles	1.0	1.82894
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fluoxetine-2453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.259
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98082
BRD-K98374711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52832
ESCRT IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6233
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIN1	Pathway Commons Protein-Protein Interactions	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	7.7246
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919881
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17083
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3913-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27682
clonus	HPO Gene-Disease Associations	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.0785
BRD-K37120019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00362
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26617
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.50829
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9186_KD_Ptbp1_SRP348448	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.90289
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82291
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.373
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
c16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01856
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498832
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Field CA1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00504
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-519d	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32263
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.494
DNAJC9	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.03215
BRD-K17574409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87896
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6833
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050917
HNF4A	ChEA Transcription Factor Targets	1.0	null
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09787
Hereditary spastic paraplegia 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
rheumatoid arthritis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
SEC63	Pathway Commons Protein-Protein Interactions	1.0	null
BL434 (NCOA1)	NURSA Protein Complexes	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.06774
Growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91271
icSARS CoV_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74824
Hereditary spastic paraplegia 44	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
ARID3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02182
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95552
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12571248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10768
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05336
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50342
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GART	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K94962942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3325
sulfamerazine-2181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53191200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71234
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
flurbiprofen-5269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.08444
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.243
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
Hereditary spastic paraplegia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55561
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40467
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964867
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29209
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26254
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31695
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23995
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93301
drofenine-3455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842995
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.867
microtubulekinesin	GeneRIF Biological Term Annotations	1.0	null
babinski sign	HPO Gene-Disease Associations	1.0	null
SNU182	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52102
BRD-K85475457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94934
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
CNOT3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94675
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heliotrine-2180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90686530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41788
Semantic dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
retrograde axonal transport	GO Biological Process Annotations 2023	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57077
BRD-K53992608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5641
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40249
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7472
Site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.799
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Microtubule minus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.696
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.174
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K58757743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03211
Cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053709
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Curcumin_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171685
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41202
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38724926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0374
BRD-K91615044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26331
region	GeneRIF Biological Term Annotations	1.0	null
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
SNU685	CCLE Cell Line Gene CNV Profiles	1.0	2.67098
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997423
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930133
impaired pupillary reflex	IMPC Knockout Mouse Phenotypes	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
Spastic paraplegia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Peripheral nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996101
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093789
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87403
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_9930_KD_TIA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.84653
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16862
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9693_KO_GPNMB_SRP382180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156342
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30262
Perturb_8191_KD_ILF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1158
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35321
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21676
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein localization to presynapse	GO Biological Process Annotations 2025	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89542
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8156
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117963
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03176
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6793
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14685
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16773
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
Hereditary Autosomal Dominant Spastic Paraplegia	DisGeNET Gene-Disease Associations	1.0	null
Axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14034
diabetic ketoacidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178403
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82691
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL756 (CSNK2A2)	NURSA Protein Complexes	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	4.6686
diabetes, type 1	GAD Gene-Disease Associations	1.0	null
BRD-K89324382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97439
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12189
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13335
BRD-K05261060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00569
NUAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21378
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AP1B1	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
butirosin-2518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.708265
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31843
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.484886
CLINT1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8628_KO_Pyk2_SRP329328	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.20841
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
paraplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.22926
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.72333
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36448
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
ESYT2	Pathway Commons Protein-Protein Interactions	1.0	null
Primary progressive multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9065
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.3878
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterograde axonal protein transport	GO Biological Process Annotations 2023	1.0	null
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39533
Thoracic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
LPS853	DepMap CRISPR Gene Dependency	1.0	7.88335
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79696
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35923
Charcot-Marie-Tooth disease type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09208
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4639
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33794
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Joubert syndrome 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03232
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12129
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01222
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Shs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06313
BRD-K35668999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56841
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
Perturb_12655_KD_Yap1/Wwtr1_SRP212072	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
E2F6	ENCODE Transcription Factor Targets	1.0	null
ESYT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47309161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07383
genetic	GeneRIF Biological Term Annotations	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00118
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.502
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
hsa-miR-4663	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K46619710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.006
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
697	COSMIC Cell Line Gene Mutation Profiles	1.0	null
altretamine-6467	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71213946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3118
testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192344
Blepharoptosis	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
HEATR3	Pathway Commons Protein-Protein Interactions	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.26886
Charcot-Marie-Tooth disease type 2R	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.31701
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875744
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03102
abnormal spinal cord grey matter morphology	MPO Gene-Phenotype Associations	1.0	null
CNOT10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K31001397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0499
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
levonorgestrel-3606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3344
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIP13	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_4788_OE_Gadd45g_SRP315685	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.46605
Perturb_2054_KD_CHERP_SRP354316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.51589
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4607
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30871
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14363
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85874
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43901
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.926764
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95328
PSMD14	Pathway Commons Protein-Protein Interactions	1.0	null
NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
APEH	Pathway Commons Protein-Protein Interactions	1.0	null
Varicosity	DisGeNET Gene-Disease Associations	1.0	null
Perturb_7646_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43792
Brain myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
neurofilament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446862
hsa-miR-4639-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCI-H2066	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39328
Perturb_8949_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.80785
BRD-A28219573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57567
Autosomal dominant intellectual developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924203
Charcot-Marie-Tooth disease axonal type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86953
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.84326
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.832329
CORO7	Pathway Commons Protein-Protein Interactions	1.0	null
used	GeneRIF Biological Term Annotations	1.0	null
ACLY	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15775_OE_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.08738
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2775
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.55503
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21837
Perturb_13914_KD_SLC45A4_SRP173763	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.29816
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053221
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05454
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86287
CARS	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64645
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16854_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.65657
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18998
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41505
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883701
Perturb_14731_KD_SUPT6H_SRP181929	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K77935284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01925
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.826055
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917145
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.04692
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19192
GFPT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30153
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
BRD-K48069820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32899
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.966
Motor peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.839
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891998
EPB41	Pathway Commons Protein-Protein Interactions	1.0	null
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC11295044-pnas.2403331121.sapp.pdf-216-ZNF33B_ZNF33B	Rummagene Transcription Factor Associations 2026	1.0	null
19185848-TableS1	GeneSigDB Published Gene Signatures	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4198
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39364
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraplegia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9657
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31125
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-503	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
NB5	DepMap CRISPR Gene Dependency	1.0	2.82399
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2939
boldine-4122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240996
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12172
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35321
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40563
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.830007
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31454
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51481
PPP2CB	Pathway Commons Protein-Protein Interactions	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.35377
COLO-792	GDSC Cell Line Gene Expression Profiles	1.0	1.66258
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LNZ308	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-646	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Hyperreflexia In Upper Limbs	DisGeNET Gene-Phenotype Associations	1.0	null
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3658_KO_SENP1_SRP133685	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.83745
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42657
RPS14_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Perturb_14148_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66743
Hereditary sensory and autonomic neuropathy type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
Polymeric cytoskeletal fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.447
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919329
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.601487
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01402
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062533
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881701
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154961,GSE154963_4_v_0_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41814083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3012
BRD-K93836438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03512
BRD-K16663346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04716
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7371
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PHACTR4	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53432
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
TNPO2	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07481
RAB11A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.37896
CRCGN014_HEPG2_3H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08401
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58026
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3474
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91692
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ensembl_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
West syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
perinuclear region of cytoplasm	GO Cellular Component Annotations 2015	1.0	null
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53291208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35141
amprolium-1979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987621
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09316
onset	GeneRIF Biological Term Annotations	1.0	null
signaling	GO Biological Process Annotations 2015	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21393
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08124
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
tubulin binding	GO Molecular Function Annotations 2025	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71986
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.501881
ioversol-3365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01903
neuron projection guidance	GO Biological Process Annotations 2025	1.0	null
Hereditary spastic paraplegia 75	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.93687
Distal axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.045
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65019
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
Methoxychlor	CTD Gene-Chemical Interactions	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02472
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31166
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78676
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055277
Spinal muscular atrophy with lower extremity predominant	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
PMC6436215-13073_2019_626_MOESM2_ESM.xlsx-PCM-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62675
Perturb_13190_KO_Wnt5a_SRP346437	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87874
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04493
pes cavus	HPO Gene-Disease Associations	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20007
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09765
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7416
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2945
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56577
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08196
Basal-Like Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
Neuronal ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
SOX2	ChEA Transcription Factor Targets	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.77394
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.00684
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.9127
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27175
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16469
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881701
BRD-K71944426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09029
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.099555
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.328834
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.815
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.972
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82144
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
successive	GeneRIF Biological Term Annotations	1.0	null
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39936
protein localization to presynapse	GO Biological Process Annotations 2023	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913039
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.087
BL5589 (MYBL2)	NURSA Protein Complexes	1.0	null
Perturb_9670_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.40791
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.69209
UBA7	Pathway Commons Protein-Protein Interactions	1.0	null
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.61382
Messenger ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.018
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1236
Axonal Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.508
GALK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K39913135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13287
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
BRD-K87404495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58923
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06659
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13432
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89364
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01291
musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_623_KO_SLFN11_SRP233180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.14686
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66191
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68671
MAZ	ENCODE Transcription Factor Targets	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cyanosis	MPO Gene-Phenotype Associations	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77514
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29182
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52547
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0774
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.03784
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14981
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887252
Amyotrophic lateral sclerosis type 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
NSC-34 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.92607
SLC25A24	Pathway Commons Protein-Protein Interactions	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.812342
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33047
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HLA-DRB1	Pathway Commons Protein-Protein Interactions	1.0	null
enoxacin-5616	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05223209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31869
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28256
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Congenital Deafness	DisGeNET Gene-Disease Associations	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6831
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00916
Burkitt lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Cytoplasmic microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
conventional	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57042334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1892
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86969
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04898
Glial cytoplasmic inclusion	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77596
postcentral gyrus, left, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892007
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35694
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0891
direction	GeneRIF Biological Term Annotations	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
invariant	GeneRIF Biological Term Annotations	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.189539
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
three	GeneRIF Biological Term Annotations	1.0	null
LRRC8C	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863016
Anosognosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23647
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22185032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8278
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13572
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871225
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12824862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60498
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3613
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83766
rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.948269
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAOY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39872
VSNL1	Pathway Commons Protein-Protein Interactions	1.0	null
CAD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.408
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00571
Lung adenocarcinoma_LUAD_TCGA-75-5125-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8318
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9011
Primary immunodeficiency disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12231
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.788
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01673
atp binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15058
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.276
SCCPDH	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04577
TBP	ENCODE Transcription Factor Targets	1.0	null
U0125-663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bone disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
type	GeneRIF Biological Term Annotations	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964353
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Perturb_8498_OE_Sox9_SRP375106	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.94606
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973206
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3241
regulation of body fluid levels	GO Biological Process Annotations 2015	1.0	null
Impaired Vibration Sensation In The Lower Limbs	DisGeNET Gene-Phenotype Associations	1.0	null
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38283
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51168
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21529
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25957
Dopaminergic synapse	KEGG Pathways 2026	1.0	null
abnormalities	GeneRIF Biological Term Annotations	1.0	null
Perry syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856386
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5879
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1666_LUNG	CCLE Cell Line Proteomics	1.0	2.19415
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08625
BGC823	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32918
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.40564
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954299
Spastic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.988
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE199606_5_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
scoliosis	HPO Gene-Disease Associations	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10253
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7	ChEA Transcription Factor Targets	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12712
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17107
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.18885
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19729
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14831
italy	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00489
Prestwick-685-2188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K50201262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37149
Perturb_8763_KD_ROBO1_SRP158939	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.50853
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2315
BL1866 (FHL2)	NURSA Protein Complexes	1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dupuytren Contracture	DisGeNET Gene-Disease Associations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.33525
Perturb_10876_KD_Glis2_SRP297106	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.11828
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.9347
PRKACB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13753_KD_EP300_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.07899
dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927483
JHUEM1	DepMap CRISPR Gene Dependency	1.0	4.12569
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.870852
microtubule binding	GO Molecular Function Annotations 2025	1.0	null
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
antigen processing and presentation of peptide antigen	GO Biological Process Annotations 2015	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2071
BRD-K45378289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3157
BRD-K52101275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61664
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052717
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.293278
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VCP	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965037
Perturb_7224_KO_CDK8/CDK19_SRP271652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.79831
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08113936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67965
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46942
BRD-A01848933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50151
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00278
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.434524
cell communication	GO Biological Process Annotations 2015	1.0	null
Katanin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
HT55	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19725
IRF1	ENCODE Transcription Factor Targets	1.0	null
ATP2B4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82007
determination	GeneRIF Biological Term Annotations	1.0	null
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79707
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66182
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054736
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
Hereditary spastic paraplegia 73	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
Generalized Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
Kinesin motor domain, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
CSDE1	Pathway Commons Protein-Protein Interactions	1.0	null
Cortical Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.69692
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K77892726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59368
BRD-K04710685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89917
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.950393
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02897
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HLA-DPB1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Pek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
MYL12B	Pathway Commons Protein-Protein Interactions	1.0	null
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
HLA-DRB3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88107
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U4B1-1726-SM-3DB9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00539
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975942
GSE57871_5_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15087_KD_Dek_SRP376094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.79226
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.365551
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_128_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
TUBB8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PABPC3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K34095226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66514
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.27511
LRPPRC	Pathway Commons Protein-Protein Interactions	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0807
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19155
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898288
GSE151612_4_v_10_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08232
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11904
thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145121
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.434
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14803
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.868128
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03506
Amyotrophic lateral sclerosis type 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
protein binding	GO Molecular Function Annotations 2015	1.0	null
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2702
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953341
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20194
Kinesin motor domain	InterPro Predicted Protein Domain Annotations	1.0	null
Immune system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75954
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19445
BRD-K83836941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17975
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8350019-mmc2.xlsx-DESeq2_Pten_vs_control_batch_LF-ENSG_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6859
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K33960497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2046
PIP	Pathway Commons Protein-Protein Interactions	1.0	null
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91321
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2328
chain	GeneRIF Biological Term Annotations	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
HSF1_KD_GDS1733_754_human_HeLa cells -  0 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9685
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9223
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863016
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955195
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HSP90AA4P	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78079
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21177
CSTF3	Pathway Commons Protein-Protein Interactions	1.0	null
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ARPC3	Pathway Commons Protein-Protein Interactions	1.0	null
parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
17009876-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
RNASE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2981
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73711
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3912
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50823
lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180652
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.721452
GNA12	Pathway Commons Protein-Protein Interactions	1.0	null
adult	GeneRIF Biological Term Annotations	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18503
central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.70442
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9151
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
AMPA glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07486
corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Factors involved in megakaryocyte development and platelet production	Reactome Pathways 2024	1.0	null
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.926
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07875
Cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.693
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02886
Perturb_9891_KD_HSPD1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.89947
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64587
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73948
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21905
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82308
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SRP72	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5529
CRCGN014_HEPG2_3H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04055
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
TUBAL3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.424
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98875
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26937
Perturb_7863_KD_METTL3_SRP226173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53298
BRD-K49552510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03816
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.581758
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12727
BRD-K48827674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37013
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82386
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAC2	Pathway Commons Protein-Protein Interactions	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
Progressive Leukoencephalopathy	DisGeNET Gene-Phenotype Associations	1.0	null
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33461
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869882
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053275
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8266
BL3195 (CDX2)	NURSA Protein Complexes	1.0	null
AKR7A2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8018_KO_PXR_SRP257678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08152
proton-transporting ATP synthase complex, catalytic core F(1)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
Perturb_9973_KD_CSTF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.92774
BRD-K95688447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31895
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.209562
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38666
NCIH1792	DepMap CRISPR Gene Dependency	1.0	6.91205
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGW	GDSC Cell Line Gene Expression Profiles	1.0	2.29842
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
dense core granule cytoskeletal transport	GO Biological Process Annotations 2025	1.0	null
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMOE-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.60428
LMAN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K48519079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88285
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60389
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48662
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065666
roxarsone-5470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
Eukaryotic translation initiation factor 2B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10926
BRD-K50004365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70373
IPO9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151494_1_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary sensory neuropathy type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
BRD-K59955428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53021
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9315_OE_MEOX2_SRP330486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62449
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.0664
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
BRD-K73692505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79249
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.1786
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TE-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81767
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34954
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2685
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOA2	Pathway Commons Protein-Protein Interactions	1.0	null
oligomers	GeneRIF Biological Term Annotations	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6824
hsa-miR-4738-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-5047	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4202
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06772291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95793
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26765
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.859474
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30495
SNU685	CCLE Cell Line Gene Expression Profiles	1.0	1.61186
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0114
anterograde axonal transport	GO Biological Process Annotations 2023	1.0	null
arginine	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4Q7-1626-SM-3K2AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883212
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2045
Charcot-Marie-Tooth disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.558
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09944
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2078_OE_PUM2_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.88296
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_5635_KD_JQ1_SRP142503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.79326
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87707
all	HPO Gene-Disease Associations	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64524
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26765
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-580	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06868
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20312
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.13355
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-641	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1287
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14161
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.215
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82404
CPT1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-106b	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Perturb_14766_KD_HDAC5_SRP265842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.6252
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6397
BRD-K17285234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25453
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76115
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wortmannin-389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.02299
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
PDHA1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_160_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30622
Perturb_14003_OE_Kcna2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.1482
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01532
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960451
microtubule	GO Cellular Component Annotations 2025	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5969
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840638
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kennedy's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8279_KD_ZNF622_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.64589
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06628
SRPR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57441129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82531
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958664
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7625_KD_ICE1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.72517
Hereditary spastic paraplegia 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.624
frame	GeneRIF Biological Term Annotations	1.0	null
urinary urgency	HPO Gene-Disease Associations	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
Hemostasis	Reactome Pathways 2014	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77182
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35321
HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1719
Charcot-Marie-Tooth disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HLA-DQB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9839
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sensory impairment	HPO Gene-Disease Associations	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885071
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51973
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06208
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPYSL2	Pathway Commons Protein-Protein Interactions	1.0	null
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996545
HCC95	CCLE Cell Line Gene Expression Profiles	1.0	1.37767
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19776
MYH14	Pathway Commons Protein-Protein Interactions	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
cycle	GeneRIF Biological Term Annotations	1.0	null
Mei2 nuclear dot complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
Pick Disease Of The Brain	DisGeNET Gene-Disease Associations	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.38504
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850038
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K53224568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95264
Perturb_17224_KD_OCT4_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
E2F4	ChEA Transcription Factor Targets	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79552
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARS	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38831170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20564
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.204668
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Resminostat_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177733
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.00684
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09139
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41562445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46243
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06688
BRD-K31559225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65422
age	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0177
Charcot-Marie-Tooth disease type X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
hsa-miR-503	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30575
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09709
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89297
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
due	GeneRIF Biological Term Annotations	1.0	null
KLC3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.70213
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41577
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Smoking initiation (ever regular vs never regular)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
BRD-K42873980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02165
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03507
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
L1236	CCLE Cell Line Gene Expression Profiles	1.0	2.07686
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33167
Arthritis, Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3143
BRD-K42971210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94284
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
Athetosis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12044
splice	GeneRIF Biological Term Annotations	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77168
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-1.90204
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.2785
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58401
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51531
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55362
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
GSE139455_2_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.98
aminoacid	GeneRIF Biological Term Annotations	1.0	null
Paroxysmal dyskinesia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84605
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41427
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07946
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06348
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-1322	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8334_KD_HCF1_SRP178073	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.15416
Perturb_13984_KO_Setd5_ERP110684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.33804
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73954
BRD-K56224420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13079
PMC4392212-gutjnl-2013-306620-s9.pdf-12-SETDB1_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
RH-18	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
hsa-miR-455-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76865
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-C1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.47345
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18259
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_14_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862993
Perturb_8294_KD_TFIP11_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86178
Urinary Bladder Sphincter Dysfunction	DisGeNET Gene-Phenotype Associations	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1609
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90335
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
deletion	GeneRIF Biological Term Annotations	1.0	null
Gout	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05017
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
linker	GeneRIF Biological Term Annotations	1.0	null
mda-mb-468 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
Hereditary sensory neuropathy type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.543587
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57787
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
GBE1	Pathway Commons Protein-Protein Interactions	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.605706
OGDH	Pathway Commons Protein-Protein Interactions	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.503
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1529
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12115687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32815
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21067
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897184
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30405
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36657
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSIP1_02_99	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59288
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111606
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88314
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Moderate Intellectual Disability	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.006
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50149147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35871
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5712_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.21547
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Multiple Sclerosis	HuGE Navigator Gene-Phenotype Associations	1.0	null
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADD1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26513
Perturb_1698_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.84039
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.01459
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
253JBV	CCLE Cell Line Gene Expression Profiles	1.0	1.44854
connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00221
Spastic ataxia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77392
frequency	GeneRIF Biological Term Annotations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.097
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40055
lingual gyrus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05262
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2325
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0433
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
Perturb_7648_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.84419
Non-small cell lung cancer	KEGG Pathways 2026	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13796
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09017
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
glipizide-1926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919694
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO1F	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06436
IA-LM	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64202
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01408
KPNB1	Pathway Commons Protein-Protein Interactions	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61278
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7037
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52415
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054878
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-455-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
DNM1	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
Paraparesis, Spastic	DisGeNET Gene-Phenotype Associations	1.0	null
Charcot-Marie-Tooth disease dominant intermediate B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14993
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3897
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
Spastic Paraplegia, Hereditary	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15254
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.917145
Supramolecular polymer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.397
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-NFKB2_NFKB2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43237307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56582
Distal Sensory Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
K562_Mocetinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0202059
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.037
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984722
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii	GO Biological Process Annotations 2015	1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85853
rilmenidine-6512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16617
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.05498
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14685
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907423
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37507
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05947
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24216
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915232
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20018
Perturb_15348_KD_SMARCD3_SRP329316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63889
Congenital muscular dystrophy with cataracts and intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92375
Liver Diseases	CTD Gene-Disease Associations	1.0	1.35531
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6855_KD_YTHDF1_SRP287222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.84984
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
CYFIP1	Pathway Commons Protein-Protein Interactions	1.0	null
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_818_KO_BCL7A/BCL7B/BCL7C_SRP345839	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K39979171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30003
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Charcot-Marie-Tooth disease type 2I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.673762
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.708265
EIF4G1	Pathway Commons Protein-Protein Interactions	1.0	null
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
YAP1	Pathway Commons Protein-Protein Interactions	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08625
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056727
BRD-K90527476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12833
KDM1A	ENCODE Transcription Factor Targets	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_7631_KD_AF4_SRP078067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.30314
EHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12144
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19321
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4824
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842205
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834597
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27763
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5392
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01778
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VARS	Pathway Commons Protein-Protein Interactions	1.0	null
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
motility	GeneRIF Biological Term Annotations	1.0	null
Hereditary Motor And Sensory Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44955380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13967
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3069
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary spastic paraplegia 30	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.789
motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.340173
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880647
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826352
BRD-K64424704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52106
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6436215-13073_2019_626_MOESM2_ESM.xlsx-PCM-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.720058
Perturb_17617_KO_TIP60_SRP386872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.47591
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.827908
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03219
BRD-K97368902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42202
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-103a	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Perturb_4048_KO_Pde10a_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70282
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25135
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL976 (PLK1)	NURSA Protein Complexes	1.0	null
alphasynuclein	GeneRIF Biological Term Annotations	1.0	null
abnormal motor neuron morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.202714
FKBP8	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_181_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862268
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93942001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38681
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the bladder	HPO Gene-Disease Associations	1.0	null
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.014044
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24498
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5919
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22555
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27803932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85271
intermediate stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05144
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K95648552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54173
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83031
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18689
Perturb_12295_OE_PHGDH_SRP363494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.71152
bone disease	GWASdb SNP-Disease Associations	1.0	0.212895
Urgency Of Micturition	DisGeNET Gene-Disease Associations	1.0	null
GSE176008_4_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35935
Nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.495
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
SF539	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95017
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
golgi apparatus	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.57354
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59071
Kinesin-like protein	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26809
Sarcoma_SARC_TCGA-DX-A3U5-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07871
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30093
Perturb_7168_KD_ACTG1_SRP385887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.75323
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880777
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26518
VMRC-LCD	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9213552-41467_2022_30858_MOESM6_ESM.xlsx-Hu-FGF4_and_NANOG-List_of_the_genes_correlated_with_both_FGF4_and_NANOG_expression_in_ICMd_cells_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23668
Perturb_4140_KO_Dars2_SRP233306	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.86183
GSE157049,GSE157051_6_v_2_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44722328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99483
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7968
cuneus, left, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991596
NHDF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21541
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31815
BRD-K39681206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01534
Distal Lower Limb Amyotrophy	DisGeNET Gene-Disease Associations	1.0	null
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18001
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36526
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40658
Perturb_8867_KD_PNN_SRP063860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.27611
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.874
salbutamol-2306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0829
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84159
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSP90AB4P	Pathway Commons Protein-Protein Interactions	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MCM6	Pathway Commons Protein-Protein Interactions	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64528
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79727
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsp	GeneRIF Biological Term Annotations	1.0	null
fludrocortisone-3977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.868203
BRD-K56590597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21456
BCB000038-7516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3239
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9576
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.471609
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14977
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52903
Complex cortical dysplasia with other brain malformations	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
Perturb_10035_KD_PUM1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68917
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8843
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24927
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DNM3	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.68608
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.27689
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920558
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16203778-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CNS cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
INTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73994
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6706_KD_ELOA_SRP314942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12257
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27938
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946734
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.18262
doxazosin-4988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11589
CRCGN013_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30869
PMC5054603__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
Charcot-Marie-Tooth disease type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
Parkinson disease	KEGG Pathways 2026	1.0	null
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
axon guidance	GO Biological Process Annotations 2025	1.0	null
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.876276
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160304,GSE163392_2_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65780164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22559
hiPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5466_KD_WWTR1_SRP125175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.6956
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19255
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95552
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34136030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05241
GSE200352_5_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Amyotrophic lateral sclerosis type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.608
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.673
Perturb_8948_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5888
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30026
U343	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33647
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.146174
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.27
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1917
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.011777
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.0664
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0154
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.986027
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94457
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.861
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.33941
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931233
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.337
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873582
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32363
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC62_SKIN	CCLE Cell Line Proteomics	1.0	3.06194
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17295
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60578
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831233
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4916
Necrosis	CTD Gene-Disease Associations	1.0	1.71503
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066958
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.807308
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60027
GSE254649_2_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Giant axonal neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.83032
Perturb_6420_KD_SPRY4IT1_SRP347515	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.83434
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870695
Corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
SERPINB8	Pathway Commons Protein-Protein Interactions	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
KTN1	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956294
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.23663
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96491664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10778
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14526
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8193_KD_PPIL4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.16258
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02757
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
CRCGN014_HEPG2_3H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31921
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.704
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7692
TBP-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ABC1_LUNG	CCLE Cell Line Proteomics	1.0	2.5473
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12571_KD_YBX1_SRP262465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.62305
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42406
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1804
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.608663
phentolamine-4336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hereditary spastic paraplegia 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.138
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1513
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.04089
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57214
Perturb_6487_OE_MDM2_SRP302203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.03463
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92365616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23301
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91793
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.226536
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10793
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27493
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4198
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
N-acetyl-L-leucine-6462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3345
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915986
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
antigen processing and presentation	GO Biological Process Annotations 2015	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.241
antigen processing and presentation of exogenous peptide antigen	GO Biological Process Annotations 2015	1.0	null
Charcot-Marie-Tooth disease recessive intermediate B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-82-IRX3_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4659
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16266
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary spastic paraplegia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.309
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BL6644 (EPS15L1)	NURSA Protein Complexes	1.0	null
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
Perturb_8947_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.60643
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273696
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-11A-01R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	2.5467
RERF-LC-FM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.26802
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954793
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06835
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.21016
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955969
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39797
BRD-K40102258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12033
microtubule binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
detected	GeneRIF Biological Term Annotations	1.0	null
PMC10214295-mmc4.xlsx-B_-_Beta_Cell_ZBTB16_targets-Gene_Name_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
inactivated	GeneRIF Biological Term Annotations	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRB	Pathway Commons Protein-Protein Interactions	1.0	null
SCC90	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K09275191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29159
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.956975
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957961
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX5	ChEA Transcription Factor Targets	1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
clozapine-5265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Amyotrophic Lateral Sclerosis	DisGeNET Gene-Phenotype Associations	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29003
BRD-K71876816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05686
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Perturb_9668_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.63412
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K63345683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11849
BRD-K27035180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01614
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876234
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52745
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pathways of neurodegeneration - multiple diseases	KEGG Pathways 2026	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41185648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54029
polymeric cytoskeletal fiber	GO Cellular Component Annotations 2023	1.0	null
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914857
RNPEP	Pathway Commons Protein-Protein Interactions	1.0	null
NDUFS1	Pathway Commons Protein-Protein Interactions	1.0	null
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5054603__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Egtazic Acid	CTD Gene-Chemical Interactions	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998811
FAR1	Pathway Commons Protein-Protein Interactions	1.0	null
megestrol-6468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
conformations	GeneRIF Biological Term Annotations	1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
BRD-K55414200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72369
r3 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05144
Classical Lissencephaly	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06459
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9131
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
drives	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98385
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5138
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE241848_1_v_0_tsc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06094529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36246
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11602
Perturb_1354_OE_U11_SRP314103	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.9069
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
Endocytosis	KEGG Pathways 2026	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1974
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arthritis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47009
BRD-K50068274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81856
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71493
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.30798
Spastic paraplegia 10	ClinVar Gene-Phenotype Associations	1.0	null
Amyotrophic lateral sclerosis type 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic variability	HPO Gene-Disease Associations	1.0	null
hsa-miR-519a	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49692
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11677
REST	ENCODE Transcription Factor Targets	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24416
MSN	Pathway Commons Protein-Protein Interactions	1.0	null
Ribonucleoprotein granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.833
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0
BRD-K66541877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77125
BRD-K43918778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18306
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053972
generation	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Charcot-Marie-Tooth disease type 4J	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_326_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.03609
BRD-K47582411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32601
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7061
A498	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89141
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14595
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9063
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71821
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.95299
ATP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
Hereditary spastic paraplegia 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	1.0	2.01988
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12379
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Machado-Joseph disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76515
PPT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22977
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45457
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.282926
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.216
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0971
UQCRC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8232
RANBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2809
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.54857
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70439
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.39464
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
represent	GeneRIF Biological Term Annotations	1.0	null
GSE217541,GSE217543_0_v_1_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	4.10464
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981826
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5041
kindred	GeneRIF Biological Term Annotations	1.0	null
pirenperone-5639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.470018
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11973
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal spinal cord morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_7169_KD_CD81_SRP385887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.86303
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spastic Gait	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50167
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29118
developing	GeneRIF Biological Term Annotations	1.0	null
Sensorimotor Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
Hereditary spastic paraplegia 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
Arthritis, Juvenile Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.190723
vesicle transport along microtubule	GO Biological Process Annotations 2025	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6608
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06333
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14654
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
axon guidance	GO Biological Process Annotations 2023	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterograde trans-synaptic signaling	GO Biological Process Annotations 2023	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
microtubule-based process	GO Biological Process Annotations 2015	1.0	null
mestranol-4792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Adaptive Immune System	Reactome Pathways 2014	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.04076
Charcot-Marie-Tooth disease axonal type 2T	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
GSE210580_3_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
BRD-K39624517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89501
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6049
GSE165307_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEG-01	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47398
Arthritis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
BRD-K56857396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30069
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978634
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04818
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.307397
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
Microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Spinocerebellar ataxia type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
autoimmune disease of gastrointestinal tract	GWASdb SNP-Disease Associations	1.0	1.40141
EIF3D	Pathway Commons Protein-Protein Interactions	1.0	null
BL809 (PRKAA1)	NURSA Protein Complexes	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083059
ADRBK1	Pathway Commons Protein-Protein Interactions	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.479
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8202
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
CST4	Pathway Commons Protein-Protein Interactions	1.0	null
GCH1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
BRD-K85294251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78727
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
disease	GWASdb SNP-Disease Associations	1.0	0.045228
G-MEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.09101
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kinesin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HS600T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74583
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38296
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40758
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.696
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964142
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATP2B2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47029
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33402
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	10.4044
biomarker	GeneRIF Biological Term Annotations	1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A17687311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1173
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0133
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07021
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K42899345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92477
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918937
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.044515
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38666
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081178
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057901
Neoplasms	CTD Gene-Disease Associations	1.0	1.13997
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058792
axonogenesis	GO Biological Process Annotations 2023	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.003
ELMO2	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40974
OLA1	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the knees	HPO Gene-Disease Associations	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2914
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0665
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89622
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-2.33754
Perturb_8293_KD_SUPV3L1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
bephenium hydroxynaphthoate-5628	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Charcot-Marie-Tooth disease type 2B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
urinary bladder sphincter dysfunction	HPO Gene-Disease Associations	1.0	null
Perturb_7312_KO_CASC3_ERP118046	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.46486
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL4516 (ATRX)	NURSA Protein Complexes	1.0	null
limb muscle weakness	HPO Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
properties	GeneRIF Biological Term Annotations	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6559
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.314
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050666
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068229
hsa-miR-4720-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Perturb_17219_KD_SOX2_ERP128142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27621
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11545_KD_TARBP2_SRP196881	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69544
GSE157594_3_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03285
Charcot-Marie-Tooth disease type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8329_KD_FTO_SRP125734	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0802
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29565
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02251
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
neomycin-1383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH196_LUNG	CCLE Cell Line Proteomics	1.0	4.89736
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.14995
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lewy body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.705
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01869
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
5666823-609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852539
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7082
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3886_KD_CTR_SRP124930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.58486
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08932
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.27929
WASF2	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907075
impaired pupillary reflex	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16904
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56381552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.90799
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
hsa-miR-1910	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
HCC-827	COSMIC Cell Line Gene CNV Profiles	1.0	2.07776
Troyer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.773
Juvenile Arthritis	DisGeNET Gene-Disease Associations	1.0	null
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34838
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K43192836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24164
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05066
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24084
abnormal motor neuron morphology	MPO Gene-Phenotype Associations	1.0	null
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.408752
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.29438
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55936
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00793
families	GeneRIF Biological Term Annotations	1.0	null
NCKAP1L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26625
type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.136135
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA2	Pathway Commons Protein-Protein Interactions	1.0	null
PRKACA	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4728-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
BRD-K24532125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51107
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LNZTA3WT4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.42799
spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319863
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11854
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41382
BRD-K43287163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21181
RHO GTPases activate KTN1	Reactome Pathways 2024	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9692
general	GeneRIF Biological Term Annotations	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45677
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
kinesin5	GeneRIF Biological Term Annotations	1.0	null
BRD-K85656316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26117
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
autosomal	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02713
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14153
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ACTN3	Pathway Commons Protein-Protein Interactions	1.0	null
K562_Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177708
BRD-K72379955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17407
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kinesin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.936
atpase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09896
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10189495-mmc7.xlsx-TCF4_wk1-gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88314
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96382853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30133
estradiol-121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vesicle transport along microtubule	GO Biological Process Annotations 2023	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15898103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21319
YKG-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.86841
polyneuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.563723
Cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.518
Perturb_9666_Mut_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.14693
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.848307
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873176
BRD-K58412301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03713
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68838
Lethal congenital contracture syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29065
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829201
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00327
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8017
CLDN1_OE_GDS3510_31_human_CL1-5 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
Primary progressive aphasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.09226
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13567
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31008
KIF5B	NURSA Protein-Protein Interactions	1.0	0.56253
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
early	GeneRIF Biological Term Annotations	1.0	null
BRD-K20199304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66554
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19002
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97945
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941086
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.013585
unresponsive to tactile stimuli	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.077
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52137
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21137
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050362
Myoclonic Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
NCIH441	Achilles Cell Line Gene Essentiality Profiles	1.0	1.20341
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.339791
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of lower limb joint	HPO Gene-Disease Associations	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
Myelin sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.963588
Somatodendritic compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.135
vitro	GeneRIF Biological Term Annotations	1.0	null
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
BRD-K47461610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3626
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18821
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13223
inhibitory	GeneRIF Biological Term Annotations	1.0	null
BRD-K97962579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00033
dystonia, DOPA-responsive	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18568
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	2.36675
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6618
Charcot-Marie-Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.528
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64926
BRD-K79355381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42549
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189859
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Hereditary spastic paraplegia 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16947_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.5055
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16566
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09933
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04532
BRD-K29338816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36293
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axonal growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058157
Perturb_12554_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57045
FAM49A	Pathway Commons Protein-Protein Interactions	1.0	null
CUL4B	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03589
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053475
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00806
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF2	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5204
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87571
Basolateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13666
synaptic vesicle localization	GO Biological Process Annotations 2023	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71034
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03749
BRD-K55069932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26313
Hereditary spastic paraplegia 43	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.847
BRD-K08353229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09645
293n3s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69264
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1962
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10105
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.344
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55503
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866834
Perturb_4745_KD_ADAR1/ADAR2_SRP050149	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.03863
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97775
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
fipexide-5737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal respiratory function	MPO Gene-Phenotype Associations	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14014
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8392
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18777
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80332123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55929
spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075041
NCIH23	DepMap CRISPR Gene Dependency	1.0	3.12193
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92551
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8273_KD_RPS19_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.18336
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neurodegeneration with brain iron accumulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08625
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
Supramolecular fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.398
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52097
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57525
Connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03232
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39024
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7571
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00104
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05159
Pontocerebellar hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.515
Brain Diseases	CTD Gene-Disease Associations	1.0	1.01739
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64099
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838214
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8350-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951304
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1597
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.126236
SAP30	ENCODE Transcription Factor Targets	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
kinesin complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20217
Axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.319
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0041
EIF3H	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.111945
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94212
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
CBC802 ()	NURSA Protein Complexes	1.0	null
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_730_KD_ELAVL1_SRP293637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86804
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_3_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUSA	DepMap CRISPR Gene Dependency	1.0	2.30825
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF4G3	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15023_KD_RelA_SRP078053	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.6252
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2502
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34143
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947711
axon guidance	GO Biological Process Annotations 2015	1.0	null
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XPO1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996919
Demyelinating peripheral neuropathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
neuronal	GeneRIF Biological Term Annotations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21264
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37168
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10027
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18001
basomedial amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01359
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_14_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.12805
Psoriasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3058
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00489
CRCGN015_HEPG2_48H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12515
mammary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087825
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3694_KO_ANGPTL8_SRP376269	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.0061
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.729
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840914
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K90746817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13737
CHD7	ENCODE Transcription Factor Targets	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood coagulation	GO Biological Process Annotations 2015	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.087
GTEX-XUZC-1826-SM-4BRVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06457
BRD-K21927299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25166
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17106
Perturb_8264_KD_EEF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.64637
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.986891
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
latamoxef-5609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.25848
A101D_SKIN	CCLE Cell Line Proteomics	1.0	2.57121
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57162
hsa-miR-16-5p	MiRTarBase microRNA Targets	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04349
BRD-K32595757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62466
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
methylphenidate_mus musculus_gpl11180_gse33619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neuropathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1074
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0809
NCI-H747	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78394
BL2790 (PTEN)	NURSA Protein Complexes	1.0	null
PMC4172779-13048_2014_87_MOESM1_ESM.pdf-21-IRF2_IRF2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.63269
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-A20305532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.21835
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55589
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01062
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3714
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70737
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64882872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09231
Perturb_4922_KD_WTAP_ERP019668	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.90249
Perturb_2607_KD_lncSNHG7_SRP179047	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.45328
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12379
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
arthritis, rheumatoid	GAD Gene-Disease Associations	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6721
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
K562_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141971
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.139893
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
EFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13417