association dataset threshold value standardized value posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88785 Nucleus of the lateral lemniscus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45294 periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0506 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16 Rummagene Transcription Factor Associations 2026 1.0 null MT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05176 LS513 DepMap CRISPR Gene Dependency 1.0 2.36903 Brain - Amygdala GTEx Tissue Gene Expression Profiles 2023 1.0 2.74431 CHMP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68321 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_7day-MOI-10^3_None_GSE43302 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.86685 PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1 Rummagene Transcription Factor Associations 2026 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.43946 IRF1 ENCODE Transcription Factor Targets 1.0 null NarGHI complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.625 CHD2 ENCODE Transcription Factor Targets 1.0 null H2BK12ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48789 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.958486 PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR Rummagene Transcription Factor Associations 2026 1.0 null GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Inner medullary collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.361 paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15149 PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null RCOR3 ChEA Transcription Factor Targets 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null kidney TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_11212_KO_Cd36_SRP351120 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.6131 GSE62843,GSE64371_2_v_0_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE184902_4_v_1_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100314_HIP_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3279 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31627 GTEX-OOBK-2626-SM-2HMKY GTEx Tissue Sample Gene Expression Profiles 1.0 0.850873 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896552 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169590_0_v_1_rptor_human RummaGEO Gene Perturbation Signatures 1.0 null GSE174701_4_v_8_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE111247_2_v_7_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38106 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_10_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03951 Medial preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94229 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06106 HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.65281 THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7527 Perturb_17702_KO|KD_Pds5a|Stag2_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.301 CTCF ENCODE Transcription Factor Targets 1.0 null KYSE30 DepMap CRISPR Gene Dependency 1.0 2.40911 M059K CCLE Cell Line Gene Expression Profiles -1.0 -1.46027 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE214823,GSE214824_0_v_2_crtc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UPK5-1426-SM-4JBHH GTEx Tissue Sample Gene Expression Profiles 1.0 0.908171 SRY-25088423-EMBRYONIC-GONADS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE165122_0_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XBED-0826-SM-47JYC GTEx Tissue Sample Gene Expression Profiles 1.0 0.824386 GSE157594_5_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19546 GSE176093_2_v_3_mineral oil_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE247775_1_v_0_tmprss2_mouse RummaGEO Gene Perturbation Signatures 1.0 null bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11841 HT55 DepMap CRISPR Gene Dependency 1.0 4.29258 GSE237984_1_v_0_magi1_human RummaGEO Gene Perturbation Signatures -1.0 null MPHOSPH9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51902 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.899906 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2218 CCLE Cell Line Gene CNV Profiles -1.0 -1.77174 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1343 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GSE119978,GSE180930_6_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23916 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.864942 GTEX-XGQ4-0426-SM-4AT4I GTEx Tissue Sample Gene Expression Profiles 1.0 1.01747 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15427 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL1789 (PAXIP1) NURSA Protein Complexes 1.0 null r6 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56104 H3K27ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UBAP2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19049 SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE81193_3_v_5_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE74251_0_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE239844_6_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 15260889-TableS2a GeneSigDB Published Gene Signatures 1.0 null Perturb_11250_KO_Med23_SRP027536 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.31923 PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CAMA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null PMC10537816-12967_2023_4509_MOESM1_ESM.xlsx-ST18-Unnamed_4_ST18 Rummagene Transcription Factor Associations 2026 1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53998 NANOG ChEA Transcription Factor Targets 1.0 null preoptic telencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37794 NCIH1944 CCLE Cell Line Gene CNV Profiles -1.0 -1.4695 GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158743_1_v_2_nfkbia_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XV7Q-1326-SM-4BRWM GTEx Tissue Sample Gene Expression Profiles 1.0 1.14667 ZBTB7A ENCODE Transcription Factor Targets 1.0 null GTEX-QCQG-0426-SM-48U29 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899759 hsa-miR-34c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE178714_3_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null CESS COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61124 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03829 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13454 TET1 ChEA Transcription Factor Targets 1.0 null GSE210580_4_v_6_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.14316 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67678 GTEX-SUCS-0226-SM-32PLQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07328 Perturb_7111_KO_Atf4_SRP344236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.4012 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31828 periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44677 GSE70499_3_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE214823,GSE214824_5_v_7_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.964975 Precancerous Conditions CTD Gene-Disease Associations 1.0 1.22404 GTEX-PW2O-1226-SM-48TCH GTEx Tissue Sample Gene Expression Profiles 1.0 1.08092 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.841997 dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87691 hsa-miR-4731-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Galloway-Mowat syndrome 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.982 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-T6MO-0526-SM-4DM6R GTEx Tissue Sample Gene Expression Profiles 1.0 0.962473 PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null USP2_KO_GDS5079_25_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 496100525_TCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.65714 GSE166004_5_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Parataenial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12213 GTEX-UJHI-0826-SM-4IHLM GTEx Tissue Sample Gene Expression Profiles 1.0 1.04327 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NFK9-1626-SM-3LK5J GTEx Tissue Sample Gene Expression Profiles 1.0 0.897002 GSE184902_4_v_1_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE199541_2_v_4_mbd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE171292_1_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4774-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 POU5F1-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE129389_0_v_6_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.9764 dorsolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40582 A375 COSMIC Cell Line Gene Mutation Profiles 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null COV504 DepMap CRISPR Gene Dependency 1.0 6.94726 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8307_OE_GALNT3_ERP012063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.48183 GTEX-P4QS-0626-SM-3NMD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884267 TBX3-20139965-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_4426_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.95434 NCIH28 CCLE Cell Line Gene CNV Profiles -1.0 -1.48118 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8036 GSE174498,GSE174500_3_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07881 r6 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37395 eye and adnexa disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 PMC5967331-41467_2018_4384_MOESM4_ESM.xlsx-Sup_data1_with_CCF_txt-Gene_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_6941_KO_Rbm20_SRP403612 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.5104 Perturb_3575_KO_Otx2_SRP279863 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.46634 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7797 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07042 496100366_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.90532 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE158834_1_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R0-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29683 SKRC20 CCLE Cell Line Gene Expression Profiles 1.0 1.48621 mantle zone of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61015 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13081 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null R3HDM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54425 Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MED21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07239 Perturb_13203_KO_Stat3_SRP213608 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_793_KO_Nrip1_SRP327958 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.36737 RNASE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22355 ZR7530 CCLE Cell Line Gene CNV Profiles -1.0 -1.39268 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPK5-2326-SM-3P5Z8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78683 Serous carcinoma_Fallopian tube_GSE10971 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.36704 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0326-SM-4BRVV GTEx Tissue Sample Gene Expression Profiles 1.0 0.958372 Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00903 GATA1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1026-SM-4DXT1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47185 GSE135244_0_v_1_trdmt1_human RummaGEO Gene Perturbation Signatures -1.0 null Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06407 GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE168171,GSE168173_0_v_1_ddx41_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE232631_0_v_2_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SLFN13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71959 SLR21 CCLE Cell Line Gene Expression Profiles 1.0 1.36366 HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38539 ESRRB ChEA Transcription Factor Targets 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.2941 Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26904 periventricular stratum of Dg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0675 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00561 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null GSE119978,GSE180930_6_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06256 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE235587_2_v_0_mitoxantrone_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Anteroventral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17954 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.878921 RAB3A_KO_GDS2483_700_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -1.52714 GSE174498,GSE174500_3_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null TPRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83407 HERPUD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39384 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 2.14978 Perturb_10860_KO_Med13_SRP302233 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.17305 JUND ENCODE Transcription Factor Targets 1.0 null SARS-BatSRBD_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.0867 ZSWIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01033 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE175787_11_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939312 ESR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QDVJ-0926-SM-2I5FU GTEx Tissue Sample Gene Expression Profiles 1.0 0.9285 GTEX-PWCY-0926-SM-48TD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98589 hsa-miR-3976 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.6195 TRIM28_knockout_301_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.27867 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142210_9_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null TLE5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07286 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63662 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.46518 RCOR1 ENCODE Transcription Factor Targets 1.0 null nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94709 RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE174701_1_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR Rummagene Transcription Factor Associations 2026 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112760,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null liminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20182 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.52287 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.36608 GSE210885_5_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTBP2 ENCODE Transcription Factor Targets 1.0 null GSE175787_8_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4LF-0426-SM-3NMB5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25584 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04678 IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980375 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47308 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980395 GSE63048_11_v_8_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null Mammary Neoplasms DisGeNET Gene-Disease Associations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20926 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1954 DepMap CRISPR Gene Dependency 1.0 2.11934 Diabetes DisGeNET Gene-Disease Associations 1.0 null Perturb_13187_OE_Cry2_SRP303502 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.61205 Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.6391 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.54273 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2117 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.128 GSE150669_0_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null myopathy GWASdb SNP-Disease Associations 1.0 0.687994 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE221955_3_v_2_igfbp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE218879_1_v_2_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE140997_10_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null RPL24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37098 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28025 GSE235828_1_v_2_igf2_human RummaGEO Gene Perturbation Signatures 1.0 null septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01113 Perturb_5107_OE_Yy1_SRP281855 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 EP300_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO3-23340844-DLD1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null TET1-21451524-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE226316_3_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01762 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.900159 GTEX-WH7G-0526-SM-3NMBI GTEx Tissue Sample Gene Expression Profiles 1.0 0.920809 GSE216147_2_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE197555_1_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE111247_14_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.901906 ChIP_TBX3_20139965 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S33H-0826-SM-4AD5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.943269 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.88696 TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles 1.0 1.40759 GSE158197_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K79me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_TCF3_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WHPG-0226-SM-3NMB9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09113 NMB DepMap CRISPR Gene Dependency 1.0 2.13145 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37794 GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles 1.0 0.929865 GSE237040_4_v_5_notch3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE135030_8_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23854 GSE186767_1_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null TCL1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58997 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE228106_3_v_5_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76511 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null paralemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59174 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37856 NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1576 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865621 H3K79me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU72-1426-SM-46MUF GTEx Tissue Sample Gene Expression Profiles 1.0 0.895536 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1386 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4313 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE172494_2_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.906621 GSE153189_1_v_3_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE67266_5_v_3_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.871163 excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE123734_1_v_0_mien1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE221020,GSE221023_2_v_1_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-520a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.89441 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.86352 TEAD4_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMRT1-23473982-TESTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.259236 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.4381 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE246195,GSE246305_4_v_5_sin3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE174506_0_v_1_ror2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12179 22RV1 DepMap CRISPR Gene Dependency 1.0 2.74681 NANOG_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1286 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.3328 GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.15893 GSE140997_4_v_3_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35884 GSE213410_2_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures 1.0 null precuneus, left, inferior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.829753 ROS50 DepMap CRISPR Gene Dependency 1.0 6.93467 GTEX-WFJO-0626-SM-4LVMC GTEx Tissue Sample Gene Expression Profiles 1.0 1.02783 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Necrosis CTD Gene-Disease Associations 1.0 1.7544 TAF7 ENCODE Transcription Factor Targets 1.0 null GSE193258,GSE193259_9_v_0_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3322 intermediate stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08934 639V DepMap CRISPR Gene Dependency 1.0 3.45937 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null superior rostral gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856596 orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.25166 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25946 TCF12 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4786-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 EW22 DepMap CRISPR Gene Dependency 1.0 3.02444 cell part LOCATE Predicted Protein Localization Annotations 1.0 null mRNA_RXRA_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null RPL23A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64294 Nucleus accumbens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08649 SNU324 CCLE Cell Line Gene Expression Profiles -1.0 -1.77358 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.2099 15260889-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7833 dorsomedial nucleus, terminal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03002 vitamin c_mus musculus_gpl6246_gse32994 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE125007,GSE125008_4_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE232223_1_v_0_letmd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966365 NCIH1836 CCLE Cell Line Gene CNV Profiles 1.0 2.68146 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865621 GSE160373_1_v_2_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null r6 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6089 GTEX-TKQ1-0326-SM-4DXSM GTEx Tissue Sample Gene Expression Profiles 1.0 1.04817 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE199255,GSE199356_3_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12036 GSE244072_11_v_1_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE205021_3_v_1_fenofibrate_mouse RummaGEO Drug Perturbation Signatures 1.0 null PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DMRT1 ChEA Transcription Factor Targets 1.0 null GTEX-QCQG-0626-SM-48U21 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946612 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61956 GTEX-T8EM-0226-SM-3DB7C GTEx Tissue Sample Gene Expression Profiles 1.0 0.824527 vascular disease GWASdb SNP-Disease Associations 1.0 0.144067 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.30906 TCF3 ENCODE Transcription Factor Targets 1.0 null GSE120370_0_v_6_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38226 GSE158815_1_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 1.54518 GTEX-QDVJ-0726-SM-48U1W GTEx Tissue Sample Gene Expression Profiles 1.0 1.27374 hsa-miR-4423-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51244 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC4A1AP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09707 GSE158197_0_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7583 PMC6420765-12864_2019_5550_MOESM5_ESM.xlsx-D9_vs_D15-Unnamed_4_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37262 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles 1.0 1.18565 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.507377 TUBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39878 NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WY7C-0226-SM-3NB37 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06371 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84286 H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null E2F1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CHP126 CCLE Cell Line Gene CNV Profiles -1.0 -1.93748 Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WYJK-1326-SM-3NB2T GTEx Tissue Sample Gene Expression Profiles 1.0 1.86796 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0614 GSE247764_3_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures -1.0 null central part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20182 GPKOW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03336 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.0579 GSE227592_13_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28553 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE211744_2_v_1_gdf15_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU5 CCLE Cell Line Gene CNV Profiles -1.0 -1.68319 Rectum adenocarcinoma_READ_TCGA-CL-4957-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE189653,GSE203344_5_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26989 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.882281 GSE123943_1_v_3_sox1_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-891b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE157594_0_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null hypothalamus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.900838 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.7596 intermediate stratum of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12615 GTEX-SNOS-0226-SM-32PLR GTEx Tissue Sample Gene Expression Profiles 1.0 0.912973 GSE119978,GSE180930_2_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null HNF4G ENCODE Transcription Factor Targets 1.0 null ES5 DepMap CRISPR Gene Dependency 1.0 2.7314 GSE122990,GSE123061_0_v_1_urod_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE227891_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0678 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02614 Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_5_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22079 GSE100316_5_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.325 kidney HPA Tissue Gene Expression Profiles 1.0 1.5267 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A62O-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE220520_1_v_7_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0109 SNU1079 CCLE Cell Line Gene Expression Profiles 1.0 1.52188 GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100431_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04569 Skin Cutaneous Melanoma_SKCM_TCGA-OD-A75X-06A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11195_KO_Pparg_SRP294559 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.10679 SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -2.74239 GSE215351,GSE215794_2_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81842 Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10653 GSE91015_0_v_1_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17538 UBTF ENCODE Transcription Factor Targets 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98657 GSE217405_3_v_2_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null lateral posterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44677 GSE248770_0_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles 1.0 1.45255 GSE195568_6_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null RSL1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18121 GSE160373_5_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE184902_3_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.964558 GTEX-X15G-0526-SM-3NMB7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.920439 GSE122101,GSE122103_3_v_4_ssu72_mouse RummaGEO Gene Perturbation Signatures -1.0 null SLC25A45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64001 GSE181513_2_v_1_usp7_human RummaGEO Gene Perturbation Signatures -1.0 null LU-139 COSMIC Cell Line Gene Mutation Profiles 1.0 null r6 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25472 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13359 GSE165174,GSE165175_0_v_2_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null MDAMB453 DepMap CRISPR Gene Dependency 1.0 3.65331 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07777 MAFK ENCODE Transcription Factor Targets 1.0 null GSE163862_2_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00575 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60024 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRL-2626-SM-2I3F1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24786 KLE CCLE Cell Line Gene CNV Profiles 1.0 1.61241 GSE153124_4_v_0_dsg2_mouse RummaGEO Gene Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02339 KML1 DepMap CRISPR Gene Dependency 1.0 2.5601 FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.0615 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.960202 artery disease GWASdb SNP-Disease Associations 1.0 0.191219 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null U-87-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_11148_KD_Cx43_ERP124601 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.18685 UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2YK-2226-SM-32QPT GTEx Tissue Sample Gene Expression Profiles 1.0 1.25091 Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.1213 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01226 GSE189653,GSE203344_2_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178714_6_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03064 PAX5 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null GSE173578_1_v_0_atf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IM-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1200 TargetScan Predicted Conserved microRNA Targets 1.0 0.050854 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18278 Perturb_4427_KO_Eed_SRP172483 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.61769 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31257 Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral tegmental area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.900998 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23616 LN319 CCLE Cell Line Gene CNV Profiles 1.0 2.25433 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LOVO DepMap CRISPR Gene Dependency 1.0 6.23853 GSE159084_0_v_1_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15 Rummagene Transcription Factor Associations 2026 1.0 null TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14872 H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7518891-elife-58374-supp1.xlsm-0_585-SOX11_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.95744 CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE70499_3_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MT-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.839008 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210655_1_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09187 CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -2.14532 GTEX-W5WG-1726-SM-4LMI5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03956 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1260b TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 GSE241036_4_v_1_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null parvicellular (lateral) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.939969 hsa-miR-1260 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 GSE172146_2_v_0_mettl1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE210655_3_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Estimated glomerular filtration rate GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 TET1-21490601-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE207611,GSE207612_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE112762,GSE112767_2_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QDVN-1626-SM-48TZC GTEx Tissue Sample Gene Expression Profiles 1.0 2.79321 GTEX-X3Y1-0726-SM-3P5YU GTEx Tissue Sample Gene Expression Profiles 1.0 0.875881 MAZ ENCODE Transcription Factor Targets 1.0 null r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36636 r3 pontine raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13858 Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.843728 GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null chr1_18471209_A_G_b38 GTEx eQTL 2025 1.0 8.20528 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARA-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null Liver enzyme levels (gamma-glutamyl transferase) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.439307 ABCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04846 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07809 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.873399 Perturb_3415_KO_Cdx2_SRP093647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00543 hsa-miR-4308 TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSS131R DepMap CRISPR Gene Dependency 1.0 2.21443 Perturb_8356_KO_HKDC1_SRP346010 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-PX3G-0826-SM-48TZS GTEx Tissue Sample Gene Expression Profiles 1.0 1.19579 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS79 CCLE Cell Line Gene CNV Profiles 1.0 1.5459 496100612_HIP_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14062 NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TIA1_KO_GSE54418_265_mouse_midbrain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles 1.0 0.855468 hsa-miR-330-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.03694 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.981948 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.872269 GSE209582_1_v_2_chloroquine_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.76109 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-F2-A7TX-01A-33R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mIMCD-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.912 GTEX-WFON-1126-SM-4LVMA GTEx Tissue Sample Gene Expression Profiles 1.0 1.28641 RT112 DepMap CRISPR Gene Dependency 1.0 5.81844 Perturb_12092_KD_Krt14_SRP066319 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.93896 PMC7681055-ACEL-19-e13226-s014.xlsx-Sheet1-Ryk-independent_FOXO3_targets_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null GSE186440,GSE186443_1_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990367 ZNF449 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2655 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.900782 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18481 urinarybladder_5c HPA Tissue Sample Gene Expression Profiles 1.0 1.25613 Lung adenocarcinoma_LUAD_TCGA-55-6981-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146982_3_v_1_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE151119_3_v_0_hsf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null COPZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14212 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IPO13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62088 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE189653,GSE203344_2_v_0_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Pelvic organ prolapse (moderate/severe) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 Perturb_787_KD_Irf3_SRP074478 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.40598 GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931841 increased vertical activity MGI Mouse Phenotype Associations 2023 1.0 null GSE227592_4_v_3_adar_human RummaGEO Gene Perturbation Signatures 1.0 null first (dorsal) preoptic domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12036 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null SKOV3 DepMap CRISPR Gene Dependency 1.0 6.50091 GSE228106_0_v_5_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GSE239844_6_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.2472 mRNA_SOX2_17515932 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null MES-SA COSMIC Cell Line Gene Mutation Profiles 1.0 null Fatty Liver CTD Gene-Disease Associations 1.0 1.50323 GSE158632_2_v_4_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null KCNJ11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54629 SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 1.75258 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr1_18478428_A_G_b38 GTEx eQTL 2025 1.0 1.31601 triangular septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46679 SNU869 CCLE Cell Line Gene Expression Profiles 1.0 1.36819 terminal paraventricular area of THyA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26904 TE5 CCLE Cell Line Gene Expression Profiles 1.0 1.63398 GSE92364_0_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 2.23609 GSE239844_7_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null KO52 CCLE Cell Line Gene CNV Profiles 1.0 1.50958 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21967 GSE148695,GSE167281_0_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null KMRC3 CCLE Cell Line Gene Expression Profiles 1.0 1.54076 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE150134_1_v_0_scn5a_human RummaGEO Gene Perturbation Signatures -1.0 null EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOSL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE199660_1_v_3_secretin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10071 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.72846 GSE157594_5_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Estimated glomerular filtration rate in non-diabetics GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.730103 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.954415 Parametrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 u TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.721 Medullary collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.62 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.81545 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20682 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26561 cellular_component GO Cellular Component Annotations 2015 1.0 null SLR26 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 GSE210580_4_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE160083,GSE160084_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56934 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null U251MGDM DepMap CRISPR Gene Dependency 1.0 2.39238 nod2_21335489_hek293_lof_human_gpl570_gds4416 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.08381 Perturb_9479_KO_Mecp2_SRP154883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.95841 vertical nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47308 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 2.55616 GSE216147_0_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE102675_2_v_1_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsal entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07881 GSE210580_3_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11554218-ppat.1012673.s015.xlsx-Sheet_A-IRF1_Target_Gene_Lists_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null M059K DepMap CRISPR Gene Dependency 1.0 3.11929 superficial stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89471 GSE81193_3_v_2_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null GSE193258,GSE193259_9_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.917026 GSE112860_9_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8409_KO_Yap1/Wwtr1_SRP143461 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.51937 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09853 isthmus proper Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30152 GSE162276_2_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null urinary bladder HPA Tissue Gene Expression Profiles 1.0 0.926492 LSM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40564 rostral interstitial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03002 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null GSE155852_0_v_2_apigenin_mouse RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12521 GTEX-RN64-1626-SM-48FD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75873 GSE167886_3_v_1_chd7_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE239844_11_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_17177_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE112760,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38975 Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles 1.0 2.04655 Perturb_13210_KO_Mbd3_ERP001253 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 2.08547 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55815 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4701-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GSE143955_1_v_2_ripk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE88819_5_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01732 hsa-miR-4314 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 GSE150055_0_v_2_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.911117 GSE161800_0_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE119978,GSE180930_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_12035_KO_Ccr2_SRP247656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.77143 GSE206729_4_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures -1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877961 SFTPC_KO_GDS4876_476_mouse_Lung Type II cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_5_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE149901_2_v_1_anlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE150669_2_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.21102 Perturb_17183_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47653 KMRC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.39243 GSE158197_6_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Hemorrhage CTD Gene-Disease Associations 1.0 1.05015 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60988 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43019 COGN305 DepMap CRISPR Gene Dependency 1.0 4.50876 GSE144443_0_v_6_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE146982_3_v_6_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_symbol_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39895 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE174498,GSE174500_2_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Dhori Virus_24Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.2346 GSE166783_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.11343 PCNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02126 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37794 GTEX-RWS6-1126-SM-47JXC GTEx Tissue Sample Gene Expression Profiles 1.0 0.926271 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.18125 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17256 TBX3-20139965-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null inner CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853533 GSE215351,GSE215794_1_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE133087_1_v_2_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.07003 PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2 Rummagene Transcription Factor Associations 2026 1.0 null NANOG ENCODE Transcription Factor Targets 1.0 null spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1164 MEWO CCLE Cell Line Gene CNV Profiles 1.0 1.49845 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-3177-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09084 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44523 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17 Rummagene Transcription Factor Associations 2026 1.0 null Kelch repeat type 1 InterPro Predicted Protein Domain Annotations 1.0 null GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.22651 lateral anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26904 GSE168797_2_v_0_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null GSE193402_0_v_2_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205730,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF784 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68917 GSE120612_6_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null MDA-MB-453 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56104 Glomerular Filtration Rate DisGeNET Gene-Phenotype Associations 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.867018 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01717 posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32207 GSE79572_0_v_1_pax8_human RummaGEO Gene Perturbation Signatures 1.0 null t60-adrenal_male_1w MoTrPAC Rat Endurance Exercise Training 1.0 1.58723 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NF-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-24763339-IMN-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08308 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-196b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GSE123638,GSE123639_2_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE129389_0_v_5_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null GSE171269_1_v_3_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE166536_1_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null TMEM106A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14711 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.996894 PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GSE175787_4_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE161800_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null SLVL COSMIC Cell Line Gene Mutation Profiles 1.0 null ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5355 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41965 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-613 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-XXEK-0826-SM-4BRWG GTEx Tissue Sample Gene Expression Profiles 1.0 0.897535 GSE111247_14_v_12_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null 496100656_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.34338 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31882 TAL1 ENCODE Transcription Factor Targets 1.0 null preopto-hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31882 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.423 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881475 H3K4me1_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.96567 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01639 GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.09577 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44962 Retrochiasmatic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08649 Perturb_17248_OE_Tnfsf15_SRP106312 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.6171 GSE162276_2_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52531 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29351 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3043 Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26904 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865621 YJU2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06234 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE211357_1_v_3_atg7_human RummaGEO Gene Perturbation Signatures -1.0 null BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4881 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7421 HCC-1954 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.9 NCIH2196 CCLE Cell Line Gene Expression Profiles 1.0 1.83724 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.84006 TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE114013,GSE114014_1_v_4_itraconazole_human RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.67514 TP53-20018659-R1E-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GF1B-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE235587_2_v_1_mitoxantrone_human RummaGEO Drug Perturbation Signatures 1.0 null OCIAML3 DepMap CRISPR Gene Dependency 1.0 2.94912 RASSF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08876 GTEX-W5WG-1626-SM-4LMKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.965127 GSE196671_6_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYC_01_324 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.5985 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MSH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61326 Hmgn1_KO_GDS5010_405_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null 17880687-TableS2 GeneSigDB Published Gene Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62145 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.996259 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.354 GTEX-QEL4-1226-SM-447A4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07332 GTEX-T6MO-0226-SM-32QOL GTEx Tissue Sample Gene Expression Profiles 1.0 0.959912 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE161184_0_v_1_tlr7_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.04698 hsa-miR-34a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25543 Digestive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NB-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OHPM-1026-SM-3LK74 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02315 Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30162 TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60693 GSE255680_2_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17042 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916989 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46822 E2F6 ENCODE Transcription Factor Targets 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40582 NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.63804 perilemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66407 shell of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13858 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null D423MG DepMap CRISPR Gene Dependency 1.0 3.4857 GSE169155_5_v_2_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.7584 mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08607 hsa-miR-1291 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 TP53INP2_OE_GDS5054_387_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5105 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2227 Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE212486,GSE212488_0_v_1_gata4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE102870_11_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04485 GSE241036_4_v_2_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868647 PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04124 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OUMS23 DepMap CRISPR Gene Dependency 1.0 4.48487 GSE113329,GSE113335_2_v_4_taf6l_mouse RummaGEO Gene Perturbation Signatures 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.66846 PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1 Rummagene Transcription Factor Associations 2026 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CDC26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21342 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205976,GSE205978_2_v_4_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null A704 CCLE Cell Line Gene Expression Profiles 1.0 2.03188 PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20674 RRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63911 GSE247764_4_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-U3ZN-0326-SM-3DB86 GTEx Tissue Sample Gene Expression Profiles 1.0 0.873659 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.38376 KDM5B_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW837 DepMap CRISPR Gene Dependency 1.0 2.79903 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE62843,GSE64371_4_v_0_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 1.7629 STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null Perturb_2894_KO_Ebf2_SRP102659 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.40651 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.867618 GSE146840,GSE146842_3_v_2_qrich1_human RummaGEO Gene Perturbation Signatures -1.0 null LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null ZBTB7A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR3C1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AK5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE112762,GSE112767_2_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16532 HEC50B CCLE Cell Line Gene CNV Profiles -1.0 -1.87645 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null lower dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31882 peduncular subparaventricular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-DLX5_DLX5 Rummagene Transcription Factor Associations 2026 1.0 null Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.17995 NR2E1_01_306 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.09583 LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE153871_5_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE86507,GSE86509_7_v_9_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null skeletal muscle HPA Tissue Protein Expression Profiles 1.0 2.04572 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_9_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MDAMB175VII CCLE Cell Line Gene Expression Profiles 1.0 1.45181 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 78.2852 CEBPB ENCODE Transcription Factor Targets 1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kelch-type beta propeller InterPro Predicted Protein Domain Annotations 1.0 null Perturb_13461_KO_Pnpla2P_SRP261793 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.50726 BT16 DepMap CRISPR Gene Dependency 1.0 2.76759 PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE205163,GSE205164_5_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84863 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 NCIH1385 CCLE Cell Line Gene CNV Profiles -1.0 -2.4617 Perturb_11712_KO_Kpna3_ERP009054 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE217405_3_v_2_osimertinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24099 FAM98B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38462 central part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33653 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22539 preoptic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147283_1_v_3_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null GSE207514,GSE207515_2_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null Retinal vasculopathy with cerebral leukodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.661 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.5812 TCF12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-1626-SM-47JYN GTEx Tissue Sample Gene Expression Profiles 1.0 1.23666 SA1-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39895 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0672 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870508 Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE199255,GSE199356_4_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_9782_KD_Esrrb_SRP321923 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.47713 kidney_b HPA Tissue Sample Gene Expression Profiles 1.0 1.59367 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Np TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.865 ECC12 CCLE Cell Line Gene Expression Profiles -1.0 -2.69014 PPARG ChEA Transcription Factor Targets 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AKT1_knockout_211_GSE39699 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.4765 GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2284 muscle tissue disease GWASdb SNP-Disease Associations 1.0 0.220143 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null SFTPC_KO_GSE35989_48_mouse_lung (type II cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null IMR32 CCLE Cell Line Gene CNV Profiles -1.0 -2.04622 Diabetes Mellitus DisGeNET Gene-Disease Associations 1.0 null ES6 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null liminal part of the r5 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25922 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25993 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A148-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE144838_4_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles 1.0 1.83548 SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0726-SM-4AD5F GTEx Tissue Sample Gene Expression Profiles 1.0 0.847814 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980395 c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CHSA0011 COSMIC Cell Line Gene Mutation Profiles 1.0 null SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55013 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13165 GATA2-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.11571 GSE157383_0_v_1_abemaciclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE80098,GSE80366_0_v_8_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59055 E2A MotifMap Predicted Transcription Factor Targets 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028543 CTV1DM DepMap CRISPR Gene Dependency 1.0 3.96354 KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76511 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.93328 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.76109 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_2174_KO_Nlrp3_SRP366634 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.55031 mantle zone of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11122 GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93821 ARID3A ENCODE Transcription Factor Targets 1.0 null GSE146982_7_v_6_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11934 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01717 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 REST ChEA Transcription Factor Targets 1.0 null GSE150669_2_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null DUXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01531 PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A ChEA Transcription Factor Targets 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.49032 Perturb_2890_KO_Mecp2_SRP154883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.95455 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TET1-21451524-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.5126 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19144 hsa-miR-3124-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 core part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81842 hsa-miR-1 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.894907 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-POMQ-0826-SM-3P61H GTEx Tissue Sample Gene Expression Profiles 1.0 1.22677 TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0826-SM-48FD3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.58692 MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE199606_2_v_7_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 1321N1 CCLE Cell Line Gene CNV Profiles 1.0 1.41793 GSE150669_0_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.916482 H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EWSR1 ChEA Transcription Factor Targets 1.0 null GSE158197_6_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC7518891-elife-58374-supp1.xlsm-0_585_3D_2days-SOX11_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null GSE75976_3_v_6_abl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-0826-SM-3NB2K GTEx Tissue Sample Gene Expression Profiles 1.0 1.02827 Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142210_3_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH446 DepMap CRISPR Gene Dependency 1.0 2.04532 GSE122101,GSE122103_0_v_1_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3657 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-1226-SM-48TCO GTEx Tissue Sample Gene Expression Profiles 1.0 0.875113 GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null OVK18 DepMap CRISPR Gene Dependency 1.0 2.37701 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 Perturb_11215_KO_Gpr151_SRP359303 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.6616 intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07881 NR3C1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE81193_3_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null PPARG-20887899-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13613 GSE175787_8_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE149880_0_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7124_KO_Prkcd/Prkce_SRP049245 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 17.2434 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953061 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-01A-02R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152734,GSE152735_2_v_0_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE218819_3_v_4_kdm5b_human RummaGEO Gene Perturbation Signatures -1.0 null Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE124920_1_v_2_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55198 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles 1.0 1.9009 AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20182 SUPT11 CCLE Cell Line Gene CNV Profiles 1.0 1.85249 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_10_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03529 outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43822 ZNF729 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58184 BMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85035 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9518 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.129691 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7089-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I1-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE188382_4_v_0_sirt5_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4Q7-0926-SM-4AD5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.16374 TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BL465 (AHCYL2) NURSA Protein Complexes 1.0 null GSE227891_5_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null CDC45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07884 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE237040_6_v_3_notch3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SE5C-0726-SM-4BRWY GTEx Tissue Sample Gene Expression Profiles 1.0 1.10926 GSE193258,GSE193259_9_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null SKRC31 CCLE Cell Line Gene Expression Profiles 1.0 1.42092 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148263_6_v_0_trim3_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE191105_0_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.988 mantle zone of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22702 GSE102870_1_v_2_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null GSE207514,GSE207515_1_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56893 Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5655 Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969044 intermediate stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19987 disease GWASdb SNP-Disease Associations 1.0 0.031336 GATA3-21867929-TH1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GATA2-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 EZH2 ENCODE Transcription Factor Targets 1.0 null GSE165682_4_v_3_ptbp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH2170 DepMap CRISPR Gene Dependency 1.0 2.31351 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 9.10399 GSE171292_5_v_2_ehhadh_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4QS-1126-SM-3NMD5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.74151 lateral part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05016 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BBC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18866 hsa-miR-647 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 CCM2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41038 urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE214931_4_v_5_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null CHL1 CCLE Cell Line Gene Expression Profiles -1.0 -1.9158 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31836 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75781 morphine_mus musculus_gpl6246_gse17731 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12186 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5435 TBP ENCODE Transcription Factor Targets 1.0 null GSE218580_1_v_3_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXO3 ChEA Transcription Factor Targets 1.0 null GSE204784,GSE204787_1_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3462 GSE81803,GSE81912_4_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Urinary system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1264 Retrosplenial area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07881 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.954415 GSE148263_6_v_9_trim3_human RummaGEO Gene Perturbation Signatures 1.0 null H3C14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.267 NR0B1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CENPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09096 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02904 hsa-miR-4783-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00453 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88027 GSE139455_2_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE146612_2_v_0_amiodarone_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_7006_KO_Mtfp1_ERP132295 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.97085 GSE229973_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930882 JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.19966 AKT1_OE_GDS2308[_473_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-Q2AG-0226-SM-2S1P4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14376 Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.5872 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29683 GSE102467_3_v_2_pazopanib_human RummaGEO Drug Perturbation Signatures -1.0 null ZR7530 CCLE Cell Line Gene Expression Profiles 1.0 1.65058 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null GSE175787_11_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5655 Brush border membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.919 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905157 GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162276_5_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41472 GSE216147_0_v_3_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5968 GSE238018_1_v_4_mxra8_human RummaGEO Gene Perturbation Signatures 1.0 null GSE217452_3_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE227592_8_v_3_adar_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_17701_KO|KD_Pds5a|Stag1_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE131798,GSE131804_2_v_0_igf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.14245 Cell Transformation, Neoplastic CTD Gene-Disease Associations 1.0 1.05274 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.76362 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.92105 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 GSE70499_3_v_6_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03824 TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GF1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE195568_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03506 PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE205070_2_v_5_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946562 ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992801 Perturb_16602_KO_Alkbh5_SRP125927 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.04678 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.921468 GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-2626-SM-2HMJM GTEx Tissue Sample Gene Expression Profiles 1.0 0.940859 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TOP2B-26459242-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE244940_0_v_1_edf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UJMC-1226-SM-4IHLI GTEx Tissue Sample Gene Expression Profiles 1.0 1.32248 pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.847435 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.997886 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70362 Perturb_5056_OE_MERVL_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.5336 17115125-SuppTable4 GeneSigDB Published Gene Signatures 1.0 null TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null GSE242367_1_v_0_dpp9_human RummaGEO Gene Perturbation Signatures 1.0 null GSE174701_5_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01281 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.0354 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.02976 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ3S-1326-SM-4BOPQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.13259 TRMT112 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84853 HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17880687-TableS1 GeneSigDB Published Gene Signatures 1.0 null SLR23 CCLE Cell Line Gene Expression Profiles 1.0 1.73507 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TG-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.9701 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE189653,GSE203344_4_v_3_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null ADCY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65374 Medial preoptic nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81842 GSE248858_6_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ICC4 DepMap CRISPR Gene Dependency 1.0 2.30623 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48789 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA420 DepMap CRISPR Gene Dependency 1.0 2.12115 GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER ChEA Transcription Factor Targets 2022 1.0 null NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1232 NCIH209 CCLE Cell Line Gene Expression Profiles -1.0 -1.48853 RRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64674 occipito-temporal gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0285 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23079 GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles 1.0 0.978195 SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE162276_2_v_0_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25887 GTEX-XUZC-1226-SM-4BRVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.29439 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7103 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.836231 GTEX-XYKS-1226-SM-4BRVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.04556 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04333 posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15801 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null KCNC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46542 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22885 SMAD4-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE234340_10_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null ESRRB-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE131887_1_v_0_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.865 TCF12_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PX3G-1526-SM-48U11 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31889 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-0826-SM-48TC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.927726 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC4 CCLE Cell Line Gene Expression Profiles -1.0 -1.57948 GSE65617_0_v_4_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ureteric bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.861 Perturb_167_KO_Itgb3_SRP305656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.6978 GI-ME-N COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930965 Liver Diseases CTD Gene-Disease Associations 1.0 1.73048 GSE174701_4_v_7_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.965039 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.95207 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00561 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.02178 GSE184892_6_v_1_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null GSE171292_6_v_0_ehhadh_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RNOR-0926-SM-2TF56 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913738 Panic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11341 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08994 PEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54837 hsa-miR-4417 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE89767_6_v_5_cebpa_mouse RummaGEO Gene Perturbation Signatures 1.0 null central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.829959 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.32354 GSE63048_11_v_5_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10789 NCI-H1734 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE176008_8_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE113817_0_v_1_bach1_human RummaGEO Gene Perturbation Signatures -1.0 null r5 part of magnocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66239 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE162276_5_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE232631_5_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE143782_7_v_11_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QEL4-2126-SM-447AE GTEx Tissue Sample Gene Expression Profiles 1.0 2.31524 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null C3A CCLE Cell Line Gene CNV Profiles 1.0 2.0331 hsa-miR-1184 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18367 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06197 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10953 A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.42931 pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0766 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31948 H3K4me1_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TP53INP2_OE_GDS5054_385_mouse_Muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-588 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 mantle zone of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30116 Perturb_13984_KO_Setd5_ERP110684 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.60883 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18354 IGR1 CCLE Cell Line Gene CNV Profiles 1.0 2.83733 hsa-miR-196a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05373 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.039357 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42582 GSE135439_0_v_1_pax5_human RummaGEO Gene Perturbation Signatures 1.0 null P2URK562 DepMap CRISPR Gene Dependency 1.0 2.67064 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6248 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14972 GTEX-PWCY-2326-SM-2I3EQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.961335 Perturb_791_KD_Irf3_SRP074478 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.5592 BCPAP CCLE Cell Line Gene CNV Profiles 1.0 1.49708 Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.574 SUIT2 CCLE Cell Line Gene CNV Profiles -1.0 -1.34322 GSE169571_3_v_4_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE135030_11_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null kidney BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.921932 STAT3 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-hgnc_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03829 GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X4XY-0826-SM-4E3JM GTEx Tissue Sample Gene Expression Profiles 1.0 0.856335 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.960691 Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138818_2_v_0_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12186 hsa-miR-3123 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3 Rummagene Transcription Factor Associations 2026 1.0 null MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29836 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35749 Perturb_10873_KO_Slc25a34_SRP342539 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.9671 hsa-miR-4453 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44686 GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.35463 Brain - Putamen (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 0.53614 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JC-1526-SM-4DM68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.926714 GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF235 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27304 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-1326-SM-4LMK1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21052 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18354 GSE67266_7_v_3_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null Costamere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.528 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null ChIP_PRDM14_21183938 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PLC-PRF-5 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.918 GSE218814_1_v_0_suv39h1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96832 arteriosclerotic cardiovascular disease GWASdb SNP-Disease Associations 1.0 0.441222 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null RXR-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_12061_KO_Stat5a_SRP012574 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 mantle zone of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 GSE133087_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null atherosclerosis GWASdb SNP-Disease Associations 1.0 0.687994 YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE151119_3_v_1_hsf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE205163,GSE205164_2_v_0_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GRANTA519 CCLE Cell Line Gene CNV Profiles -1.0 -1.41881 GSE140997_2_v_1_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24312 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 hsa-miR-4786-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.32519 GSE215351,GSE215794_4_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.072275 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.0192 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE161864,GSE161866_0_v_2_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null HNF4A ChEA Transcription Factor Targets 1.0 null SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-4432 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24429 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 1.55768 786O DepMap CRISPR Gene Dependency 1.0 3.3189 GSE146074_0_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.875 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.839788 GSE248858_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null NFIC_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55G-2426-SM-2TC5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.29845 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20357 GSE248858_1_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1963 COSMIC Cell Line Gene Mutation Profiles 1.0 null ESR1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15618_KO_Mss51_SRP215371 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.56309 GTEX-X5EB-0526-SM-46MVP GTEx Tissue Sample Gene Expression Profiles 1.0 0.842161 POLR3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84324 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.91612 Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19005 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130864_0_v_1_tincr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE199092_2_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null PRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19199 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A560-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-615-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Mammary Carcinoma DisGeNET Gene-Disease Associations 1.0 null Perturb_8710_OE_SMAD4_SRP255626 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.31546 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81854 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null IGR39 DepMap CRISPR Gene Dependency 1.0 3.40885 GSE70499_3_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Giant axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.664 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03877 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39895 GTEX-V955-0326-SM-4JBGV GTEx Tissue Sample Gene Expression Profiles 1.0 0.964146 GTEX-WEY5-1226-SM-4LMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.18353 GSE171401_1_v_0_adnp_mouse RummaGEO Gene Perturbation Signatures 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.992546 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981174 hsa-miR-4646-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -2.23205 GTEX-XMD1-0826-SM-4AT52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.965888 YY1 ENCODE Transcription Factor Targets 1.0 null septodiagonal transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Diabetic retinopathy GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 GTEX-U3ZN-2026-SM-4DXUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.28542 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE247764_1_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE130437_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE132386_2_v_0_ppara_mouse RummaGEO Gene Perturbation Signatures -1.0 null IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.899807 ITGA7_OE_GDS3209_142_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE87299_1_v_0_nr1d1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null A673 COSMIC Cell Line Gene Mutation Profiles 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902917 GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.5237 Rge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.573 GTEX-WFJO-2026-SM-4LVM3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.974463 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -2.03514 Perturb_5161_KO_Trp53_SRP048945 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.47132 SLR24 CCLE Cell Line Gene Expression Profiles 1.0 1.79018 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PKNOX1_PKNOX1 Rummagene Transcription Factor Associations 2026 1.0 null GSE158834_1_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40305 eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPIC-0926-SM-4IHLV GTEx Tissue Sample Gene Expression Profiles 1.0 0.837675 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.294276 MELJUSO CCLE Cell Line Gene Expression Profiles -1.0 -1.46453 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SIN3B ChEA Transcription Factor Targets 1.0 null GTEX-U3ZM-0126-SM-3DB8M GTEx Tissue Sample Gene Expression Profiles 1.0 1.01975 Ventromedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42208 hsa-miR-544b TargetScan Predicted Conserved microRNA Targets 1.0 0.123298 FOXM1 ENCODE Transcription Factor Targets 1.0 null posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.972529 Perturb_11252_KO_Med13_SRP302233 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.86148 intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40266 HDAC6 ENCODE Transcription Factor Targets 1.0 null GTEX-QEL4-1426-SM-447AC GTEx Tissue Sample Gene Expression Profiles 1.0 1.28825 GTEX-S4Z8-0526-SM-4AD4T GTEx Tissue Sample Gene Expression Profiles 1.0 1.41185 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1355 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.554 Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.856702 r5 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19918 GSE160083,GSE160084_2_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null USH2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.926 496100413_FWM_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03887 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null D-392MG COSMIC Cell Line Gene Mutation Profiles 1.0 null NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE230354_0_v_1_rheb_mouse RummaGEO Gene Perturbation Signatures -1.0 null USP2_KO_GSE43517_20_mouse_kidney GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE158197_2_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF644 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28864 REST ENCODE Transcription Factor Targets 1.0 null KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.25631 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19176 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861667 SNU503 DepMap CRISPR Gene Dependency 1.0 2.28577 GSE206502_2_v_1_igf2bp1_human RummaGEO Gene Perturbation Signatures -1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931841 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210377_0_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null LU-134-A COSMIC Cell Line Gene Mutation Profiles 1.0 null Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.5984 CREB_DEPLETION_GDS3487_41_human_K562 myeloid leukemia cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intermediate stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41387 LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56549 Inner medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.069 PHF8 ENCODE Transcription Factor Targets 1.0 null NCIH1563 CCLE Cell Line Gene CNV Profiles -1.0 -1.51093 GSE43041,GSE43044_0_v_1_ldb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mitochondrial pyruvate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.508 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.43093 NCI-H2066 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVTOKO CCLE Cell Line Gene Expression Profiles 1.0 2.5492 GTEX-R55C-0626-SM-2TF4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.04399 GSE129389_0_v_1_tropifexor_mouse RummaGEO Drug Perturbation Signatures -1.0 null Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.8078 nucleus of the stria medullaris (prethalamic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12677 NANOG-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.61753 Perturb_9603_KO_Satb2_SRP328167 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.9863 GSE169697,GSE169725_0_v_5_prrx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null inner SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932457 interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12027 DHX15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04211 Non-alcoholic Fatty Liver Disease CTD Gene-Disease Associations 1.0 1.27502 GSE193258,GSE193259_5_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE139455_0_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE143847_2_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GSE235701,GSE261434_0_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11238_KO_Trp53_SRP322469 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.4267 GTEX-SUCS-0626-SM-32PM5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.898561 NB14 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOSL2 ENCODE Transcription Factor Targets 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE192663_3_v_2_acly_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.046108 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GALNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23769 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59953 PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_id_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_17704_KO_Pds5b_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.1928 r5 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38114 GSE164757,GSE164759_4_v_2_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null RCOR3-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Low Density Lipoprotein Cholesterol Measurement DisGeNET Gene-Phenotype Associations 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28337 superior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.991829 Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD2/3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43797 GSE193258,GSE193259_5_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19161 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28291 GSE232714_0_v_1_raver1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE71468,GSE76476_2_v_1_rbfox1_human RummaGEO Gene Perturbation Signatures 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61921 SW1463 COSMIC Cell Line Gene Mutation Profiles 1.0 null TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4776 GSE93124_0_v_1_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32094 ACSM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40945 Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03627 stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01872 Perturb_7053_KO_Tead1_SRP229838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null PPP1R8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74159 Perturb_5100_KO_Zmym2_SRP161512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.8762 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931841 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.35743 GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.26385 NOS-1 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 GTEX-WHSB-1626-SM-3LK6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.06032 GSE118816_2_v_3_myo1c_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60024 GSE153871_0_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null SRY ChEA Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76997 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.00089 GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null PMC11324510-41587_2023_1949_MOESM3_ESM.xlsx-Supplementary_Table6-Supplementary_Table_6_TP53_pathway_genes_list_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S341-1526-SM-4AD6K GTEx Tissue Sample Gene Expression Profiles 1.0 0.968324 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205070_2_v_9_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08676 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7060-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-1226-SM-4DXUD GTEx Tissue Sample Gene Expression Profiles 1.0 1.5594 PMC7518891-elife-58374-supp1.xlsm-Common_in_3D_0_585-SOX11_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26526 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FANCM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4225 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896177 eye disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 GTEX-VJYA-1026-SM-4KL21 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3908 GSE166317_2_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2991 GTEx Lung 20-29 vs 60-69 GTEx Tissue-Specific Aging Signatures -1.0 -8.97162 GSE248769_1_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.5171 GSE165122_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null prerubral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17954 hsa-miR-150 TargetScan Predicted Conserved microRNA Targets 1.0 0.059817 GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures 1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04793 TEAD4_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01113 RFX5 ENCODE Transcription Factor Targets 1.0 null hsa-miR-449a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE157904_2_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE142210_9_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null GSE184902_3_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures -1.0 null coronary artery disease GWASdb SNP-Disease Associations 1.0 0.687994 RCOR3-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null OSRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.53187 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49G-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028521 Perturb_8633_KO_Sh3gl1/Sh3gl2_SRP082219 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.88744 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MS-1626-SM-3LK5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.32233 GTEX-S95S-0826-SM-4B64N GTEx Tissue Sample Gene Expression Profiles 1.0 1.54807 GSE156923_0_v_3_rbmx_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11214_KO_Cyp2e1_SRP355413 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.1524 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.01373 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.698704 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06002 GSE249714_0_v_1_anxa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null COLO800 DepMap CRISPR Gene Dependency 1.0 4.20878 dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37794 PAGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09903 lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08607 EIF3M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45961 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0375 GSE169155_6_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null OV7 DepMap CRISPR Gene Dependency 1.0 4.1538 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE150055_0_v_1_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null GATA2 ChEA Transcription Factor Targets 1.0 null Perturb_854_KD_Ogt_SRP297858 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.76799 GSE193258,GSE193259_5_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null MZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17268 MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null FZD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12083 CMLT1 CCLE Cell Line Gene Expression Profiles -1.0 -1.77917 GSE226584,GSE226589_3_v_0_ezh2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE80446_2_v_1_anakinra_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE206729_3_v_1_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3 Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55888 Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.17993 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF622 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12188 CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58795 IVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00255 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null RPL27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02867 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40015 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.796753 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980395 intermediate stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03627 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.294276 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.9647 GTEX-T5JC-2126-SM-32PMO GTEx Tissue Sample Gene Expression Profiles 1.0 2.89936 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posterior intralaminar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11122 NANOG-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGFBR2_knockout_292_GSE46150 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.63451 ESRRB-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null bed nucleus of the stria terminalis, mediocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06691 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.685864 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t60-adrenal_consensus MoTrPAC Rat Endurance Exercise Training 1.0 6.17592 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9373 SNU1272 CCLE Cell Line Gene Expression Profiles 1.0 1.36659 Liver TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null HDAC6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE221356_1_v_0_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC9046280-41467_2022_29963_MOESM8_ESM.xlsx-Supplementary_Fig_4B-Genes_annotated_to_enhancers_bound_by_ASCL1_ChIP_and_lost_expression_in_42D_K_D_ASCL1_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7518891-elife-58374-supp1.xlsm-Common_in_all_3_datasets_0_585-SOX11_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05448 GSE96649_1_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE139948_3_v_2_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7884 GSE171572_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_1121_KD_E2APBX1_SRP115954 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83901 RNF187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17031 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE198434_1_v_0_aspirin_human RummaGEO Drug Perturbation Signatures 1.0 null rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17691 mantle zone of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07147 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F1 ChEA Transcription Factor Targets 1.0 null GTEX-V1D1-1726-SM-4JBHB GTEx Tissue Sample Gene Expression Profiles 1.0 1.00998 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.11577 MARCKSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30641 GSE164757,GSE164759_4_v_3_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75758 GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SMAD3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31338 GSE200673,GSE200691_2_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPD ENCODE Transcription Factor Targets 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03877 SMAD4 ChEA Transcription Factor Targets 1.0 null GSE118816_2_v_1_myo1c_human RummaGEO Gene Perturbation Signatures -1.0 null GSE88819_5_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.80393 SOX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28388 horizontal nucleus of the diagonal band, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42208 GSE172020_0_v_2_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE205976,GSE205978_2_v_5_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null arteriosclerosis GWASdb SNP-Disease Associations 1.0 0.373598 Urate levels in lean individuals GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE239844_8_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14774 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06941 GSE186440,GSE186443_1_v_7_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33286 HDAC1 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4073-01B-02R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.74172 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149075_3_v_5_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 ChIP_POU5F1_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_6218_KO_H3f3b_SRP151535 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.37049 GSE175787_5_v_7_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null ESR1_ECC-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AI-0826-SM-48TZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.27938 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE162276_2_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146074_1_v_8_ly6e_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S33H-0326-SM-4AD6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.38421 hsa-miR-4449 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.40936 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03877 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null second (ventral) preoptic domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 CIAO2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45926 GSE221020,GSE221023_2_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null RBSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58449 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE139455_2_v_3_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3902 Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.900782 GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles 1.0 2.51238 hsa-miR-4538 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1048 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.19351 Perturb_16431_KD_E2f4_SRP327850 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.80592 GSE191174_0_v_1_ccdc92_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.09266 GSE208350_0_v_1_fgfr1_human RummaGEO Gene Perturbation Signatures 1.0 null RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC11968629-12672_2025_2184_MOESM1_ESM.pdf-5-AEBP1_AEBP1 Rummagene Transcription Factor Associations 2026 1.0 null T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE139455_4_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12657_KD_Yap1/Wwtr1_SRP212072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 hsa-miR-1224-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07114 17880687-TableS3 GeneSigDB Published Gene Signatures 1.0 null SUIT-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48789 ESR1_ECC-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169617_1_v_2_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null GSE116299_6_v_5_folic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE139948_3_v_6_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null RPL26L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15932 GSE126345_4_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE232631_4_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF3-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null superficial stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42208 doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12889 hsa-miR-4758-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-XPVG-0326-SM-4B653 GTEx Tissue Sample Gene Expression Profiles 1.0 0.961428 ChIP_NANOG_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59T-01A-21R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945158 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15178 GSE227592_0_v_3_adar_human RummaGEO Gene Perturbation Signatures 1.0 null Ureterolithiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 PMC7906903-41366_2020_716_MOESM2_ESM.xlsx-DEG_HMGA2-fusion-Gene_Symbol_HMGA2 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2266 NR3C1 ENCODE Transcription Factor Targets 1.0 null GSE198165,GSE198166_9_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null TLR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17047 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54138 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18354 ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0539 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.91391 PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 TBX3-20139965-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MEG-01 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE148692,GSE148695_5_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATF1 ENCODE Transcription Factor Targets 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PDX1_KO_GDS4348_360_mouse_Proximal small intestine GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE205163,GSE205164_3_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null GSE195568_3_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null SRF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12548_KO_Shank2_SRP309197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.15465 SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4296 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B6-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5536_Mut_Trp53_ERP128838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.5052 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12186 mantle zone of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87947 Perturb_17699_KO_Pds5a_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.7985 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE92364_1_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 0.95125 GSE148510_1_v_2_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null TP53-23651856-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Principal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.73 anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16844 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10349 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.971216 GTEX-P78B-0526-SM-2I5F7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853103 H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ECT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3968 CSNK2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26732 EP300_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05458 Plasma membrane respirasome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 GTEX-PX3G-0226-SM-3NB2C GTEx Tissue Sample Gene Expression Profiles 1.0 1.23345 PMC12211054-spectrum.00100-25-s0002.pdf-44-KLF4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.981464 PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1786 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05713 JUN ENCODE Transcription Factor Targets 1.0 null External cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06491 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE140997_4_v_8_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.94595 GSE146840,GSE146842_0_v_2_qrich1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE96649_1_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.7337 RUNX2 ChEA Transcription Factor Targets 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM1A_KD_GDS5055_367_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles 1.0 0.907784 GSE178714_3_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC4 DepMap CRISPR Gene Dependency 1.0 2.4086 PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q734-0326-SM-48U15 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19474 ELF1 ENCODE Transcription Factor Targets 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.06315 PPP2R5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11867 GTEX-S341-0626-SM-4AD5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.26164 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53478 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07661 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174498,GSE174500_5_v_4_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LDL cholesterol GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.830103 GSE168233_0_v_1_setdb1_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of p2B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12036 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.859078 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RASA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25245 GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null HNF4A ENCODE Transcription Factor Targets 1.0 null KURAMOCHI CCLE Cell Line Gene CNV Profiles 1.0 1.4341 hsa-miR-3940-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17179 Perturb_5247_KO_Tfcp2l1_SRP288317 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE229468,GSE229471_0_v_3_znf587_human RummaGEO Gene Perturbation Signatures 1.0 null MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.821168 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TIA1_KO_GSE54418_266_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles 1.0 1.17942 Henles loop TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 SMC4-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-RNOR-1426-SM-48FDJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00533 Perturb_12655_KD_Yap1/Wwtr1_SRP212072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 intermediate stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43299 GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE175787_13_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-1291 TargetScan Predicted Conserved microRNA Targets 1.0 0.031759 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DI-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39835 t60-adrenal_female_8w MoTrPAC Rat Endurance Exercise Training -1.0 -1.668 GSE161864,GSE161866_1_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05444 Prostate adenocarcinoma_PRAD_TCGA-EJ-5531-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.70898 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16639_KO_Tardbp_SRP278199 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.35832 GSE125007,GSE125008_6_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4428 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9727 GTEX-NFK9-1526-SM-3LK7B GTEx Tissue Sample Gene Expression Profiles 1.0 0.841594 FJX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17244 GTEX-P4QS-1026-SM-3NMCW GTEx Tissue Sample Gene Expression Profiles 1.0 0.961813 OSC-20 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE210655_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null lateral part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88134 ChIP_RCOR3_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-3141 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04975 Perturb_11241_KD_Csde1_SRP383422 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 15.2606 Neoplasms CTD Gene-Disease Associations 1.0 1.24687 intermediate stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72381 periventricular stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20182 GSE120370_4_v_1_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180813,GSE180815_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158632_3_v_1_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null GSE193258,GSE193259_2_v_0_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE125007,GSE125008_1_v_0_uhrf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null LASV_FML29 _4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.25815 Perturb_17173_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.6837 dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35963 hsa-miR-449b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE205070_2_v_7_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-525-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.232827 SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -2.53873 GTEX-T6MO-0726-SM-4DM58 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01968 GSE119978,GSE180930_2_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.325 NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 1.79514 H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE86507,GSE86509_3_v_5_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25436 PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-O5YW-1526-SM-3MJGL GTEx Tissue Sample Gene Expression Profiles 1.0 1.1185 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE254155_5_v_0_per2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6422 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04096 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4UY-0926-SM-4AD6O GTEx Tissue Sample Gene Expression Profiles 1.0 1.38438 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03627 GTEX-XUZC-0726-SM-4BOPH GTEx Tissue Sample Gene Expression Profiles 1.0 1.50249 GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE199255,GSE199356_3_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06941 CAL54 CCLE Cell Line Gene Expression Profiles 1.0 1.5966 Perturb_15122_KD_PRKAB1_SRP076036 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.87813 GATA3 ENCODE Transcription Factor Targets 1.0 null NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05493 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94709 kidney_c HPA Tissue Sample Gene Expression Profiles 1.0 1.47822 GSE239844_11_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46161 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128099,GSE128159_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837542 RT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.44846 Perturb_6550_KO_Adig_ERP017365 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.2209 GSE231524,GSE231526_0_v_1_dusp6_human RummaGEO Gene Perturbation Signatures -1.0 null MCM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3264 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NB10 DepMap CRISPR Gene Dependency 1.0 4.05961 Microspike COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.648 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7586 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.11309 SP1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE138818_1_v_0_nanog_mouse RummaGEO Gene Perturbation Signatures 1.0 null HT1197 CCLE Cell Line Gene CNV Profiles 1.0 1.33034 Perturb_2240_KO_L2hgdh_SRP093280 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -14.9717 LRRC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07832 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.909189 ATM_KD_GSE54268_661_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LXR-22158963-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-hgnc_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null SIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3121 HH CCLE Cell Line Gene CNV Profiles 1.0 1.51127 SP1 ENCODE Transcription Factor Targets 1.0 null GTEX-XUW1-1726-SM-4BOOZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.840432 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852775 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.17 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_6_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9373 GSE218879_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5817 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08994 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null TP53 ChEA Transcription Factor Targets 1.0 null hsa-miR-4329 TargetScan Predicted Conserved microRNA Targets 1.0 0.099701 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86899 mRNA_TCEA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-OHPM-2626-SM-33HC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952101 GSE119978,GSE180930_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null kidney_a HPA Tissue Sample Gene Expression Profiles 1.0 1.61609 GSE207514,GSE207515_0_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE193258,GSE193259_5_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913573 OVTOKO DepMap CRISPR Gene Dependency 1.0 2.64269 dorsal nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43457 SNU216 DepMap CRISPR Gene Dependency 1.0 2.83083 SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE190186,GSE190188_8_v_10_apoe_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE214931_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04027 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIPA1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24389 SIMA CCLE Cell Line Gene CNV Profiles -1.0 -1.75 NCIH1581 DepMap CRISPR Gene Dependency 1.0 3.72001 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.101379 AR-25329375-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COV318 CCLE Cell Line Gene CNV Profiles 1.0 1.48239 GSE156923_2_v_3_rbmx_human RummaGEO Gene Perturbation Signatures 1.0 null Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20182 Perturb_17223_KD_NANOG_ERP128142 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE111035,GSE111040_3_v_13_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE227891_5_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIC_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE140997_10_v_7_nsun6_human RummaGEO Gene Perturbation Signatures -1.0 null CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.58733 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE243683_0_v_1_s100a16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null HCV_8week-No IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.60216 dorsal part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12585 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3650 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205021_3_v_2_fenofibrate_mouse RummaGEO Drug Perturbation Signatures 1.0 null SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE210580_0_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11207_KO_Zhx2_SRP332476 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.95401 hsa-miR-206 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 CLMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10588 SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE146074_9_v_7_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE179880_7_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE119603_1_v_0_oxaliplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -2.0876 496100351_FWM_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 8.6656 NH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.38989 GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null KURAMOCHI COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_8911_KO_YAP1_SRP132362 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.6971 GSE178227_1_v_0_tet1_mouse RummaGEO Gene Perturbation Signatures 1.0 null BL2793 (TRIM24) NURSA Protein Complexes 1.0 null NCIH292 CCLE Cell Line Gene CNV Profiles -1.0 -1.72723 GSE215351,GSE215794_1_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1605 Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1246 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31828 NB17 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_5_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210842_3_v_1_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF736 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30386 hsa-miR-4265 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE211151_1_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null muscular disease GWASdb SNP-Disease Associations 1.0 0.19995 SP4 ENCODE Transcription Factor Targets 1.0 null GA-04-SF76_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.233689 GTEX-OOBJ-1526-SM-3NB1Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.955316 hsa-miR-765 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE166536_0_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null Learning Disorders CTD Gene-Disease Associations 1.0 1.04721 C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05156 SMAD3-22036565-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE152699,GSE152723_0_v_2_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.06205 SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71092 mantle zone of PThE Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12645 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE172494_3_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null increased vertical activity IMPC Knockout Mouse Phenotypes 1.0 null GOLGA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11894 Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7112_KO_Atf4_SRP344236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.29509 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0939 GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles 1.0 1.24628 r9 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08011 Perturb_11251_KO_Med13_SRP302233 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.1485 GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.984667 superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45213 H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4483 GSE132759_4_v_0_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE102870_7_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null GSE85880,GSE85881_0_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.901717 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224004,GSE224005_0_v_1_chd4_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-POYW-1326-SM-48TCG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11608 GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.911913 KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE148692,GSE148695_5_v_6_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null planum polare, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.868123 GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.851866 GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null GSE160373_5_v_4_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.95744 Perturb_3135_KO_Sox5/Sox6_SRP045626 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.1459 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3805_KO_Cftr_SRP067491 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE239844_8_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6445 TE617T CCLE Cell Line Gene Expression Profiles -1.0 -1.65031 TP53-20018659-R1E-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE112763,GSE112767_4_v_5_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE95685_2_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null TMEM145 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41947 KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XXEK-1726-SM-4BRVB GTEx Tissue Sample Gene Expression Profiles 1.0 0.877434 GLB1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08911 PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE109140_0_v_3_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null GSE219274,GSE219276_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE199255,GSE199356_4_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05629 GSE81193_0_v_4_irf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE199606_2_v_7_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.55253 GSE186440,GSE186443_0_v_5_daxx_human RummaGEO Gene Perturbation Signatures -1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Decreased_in_both_CSDE1_KD_hESC-gene_short_name_AR Rummagene Transcription Factor Associations 2026 1.0 null Urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.958105 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Smad4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.962 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19161 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Intermediate reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27163 Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCBTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49272 GSE174701_5_v_6_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mccoy TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 Parvicellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09172 Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112760,GSE112767_4_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4322 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.79969 SNU349 CCLE Cell Line Gene Expression Profiles 1.0 2.3008 BEL-7402 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.751 KYSE-150 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE188774_1_v_0_hkdc1_human RummaGEO Gene Perturbation Signatures -1.0 null KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.51968 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 1.11446 DMRT1-23473982-TESTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null stomach_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.11192 HIC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6493 PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE234340_1_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-1626-SM-3NB17 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98702 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.981174 GSE127790_13_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NAMALWA CCLE Cell Line Gene CNV Profiles 1.0 1.54202 GTEX-SJXC-1226-SM-4DM78 GTEx Tissue Sample Gene Expression Profiles 1.0 0.850008 GSE96641_3_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.01762 Disease Models, Animal CTD Gene-Disease Associations 1.0 1.14302 H2AK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57123 A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.72922 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7568 GTEX-QDVJ-1226-SM-48U1V GTEx Tissue Sample Gene Expression Profiles 1.0 1.15322 SOX2 ChEA Transcription Factor Targets 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20705 GSE140997_4_v_6_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null ChIP_ESRRB_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-QV31-0726-SM-3GAEG GTEx Tissue Sample Gene Expression Profiles 1.0 1.37444 temporal pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906382 PPP1R1A_KO_GDS1920_708_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-3620 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08649 UMRC2 CCLE Cell Line Gene Expression Profiles 1.0 2.03071 GSE138097_0_v_2_otx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140997_4_v_5_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5261 OLIG2-26023283-AINV15-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SMAD4-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KIAA2026 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52468 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.76109 GSE158197_0_v_11_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0626-SM-46MUI GTEx Tissue Sample Gene Expression Profiles 1.0 0.850432 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPIC-1126-SM-4IHLO GTEx Tissue Sample Gene Expression Profiles 1.0 2.25908 GSE158815_5_v_3_trib1_mouse RummaGEO Gene Perturbation Signatures -1.0 null AKAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12078 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.94413 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2141 CCLE Cell Line Gene Expression Profiles -1.0 -2.29028 GSE202434,GSE202438_9_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 117.705 Perturb_5169_KO_Ddx5_SRP068412 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.3715 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.848113 GSE157050,GSE157051_2_v_4_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null TCF3-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145249_0_v_2_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null CHAF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02912 Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23577 GTEX-U3ZN-1726-SM-4DXUQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00798 GSE119978,GSE180930_0_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.09249 GSE182179_0_v_3_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null GSE210885_3_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22392 GSE146982_3_v_1_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70325 GSE144838_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE146962_0_v_1_glucosamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S3XE-1226-SM-4AD4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.09202 E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A115-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null prethalamic eminence Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12645 GSE102870_3_v_9_nr1h4_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66239 GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ESR1_ECC-1_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-1426-SM-3NB1T GTEx Tissue Sample Gene Expression Profiles 1.0 0.867299 COV318 DepMap CRISPR Gene Dependency 1.0 7.74187 NPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1755 GSE212486,GSE212488_2_v_3_gata4_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of SePal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31882 YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3 ChEA Transcription Factor Targets 1.0 null r2 part of median raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17954 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KP-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Twist2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.8526 Nemaline myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.189 POU5F1 ChEA Transcription Factor Targets 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null GSE174498,GSE174500_2_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null GSE158632_2_v_5_oxyquinoline_human RummaGEO Drug Perturbation Signatures -1.0 null periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28061 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MSX1_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE200352_1_v_8_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE157050,GSE157051_2_v_3_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Perturb_15338_KO_Ldha_SRP255398 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.23867 GTEX-S4UY-1626-SM-4AD55 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19062 GSE215351,GSE215794_4_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null TP53-23651856-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE81803,GSE81912_0_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anterior hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53215 GSE126345_9_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null 17115125-SuppTable6 GeneSigDB Published Gene Signatures 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_NR0B1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC5682285-41467_2017_1744_MOESM8_ESM.xlsx-Change_in_both_CSDE1_KD_hESCs-gene_short_name_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Human - Tonsil - L2 - Mast cells HuBMAP Azimuth Cell Type Annotations 1.0 null mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930965 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C1orf43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07129 GSE246053_1_v_3_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_12122_OE_Aire_SRP250736 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.15293 SMAD4-21741376-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51331 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.90009 integral component of membrane GO Cellular Component Annotations 2015 1.0 null DJM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE157594_6_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9859 hsa-miR-330-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17256 Renal medulla cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.65 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ALAS2_OE_GDS2118_74_human_Blood GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88548 SNRPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14369 FOXO3-23340844-DLD1-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-0826-SM-2HMKF GTEx Tissue Sample Gene Expression Profiles 1.0 0.836612 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25453 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5571 tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87397 Rat-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2045 TET1-21490601-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 0.870399 NCIH1105 CCLE Cell Line Gene Expression Profiles -1.0 -1.89426 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.871134 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03877 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE117212,GSE117214_0_v_1_zbtb1_human RummaGEO Gene Perturbation Signatures -1.0 null NOVA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09062 PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9 Rummagene Transcription Factor Associations 2026 1.0 null abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.232827 Distal tip cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06298 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OXA1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32198 H3K79me2_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-V955-1326-SM-4JBHR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18002 GSE153189_1_v_0_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null ELP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.58008 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XMK1-0626-SM-4B65A GTEx Tissue Sample Gene Expression Profiles 1.0 1.02561 FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MYBBP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29082 chr1_18480564_T_C_b38 GTEx eQTL 2025 1.0 4.16042 DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17310_KO_setdb1_SRP291600 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.47215 kidney GTEx Tissue Gene Expression Profiles 1.0 1.25784 GTEX-TMMY-1626-SM-4DXTY GTEx Tissue Sample Gene Expression Profiles 1.0 1.25824 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881475 hsa-miR-186 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 CDH4-35650610-MESC-MOUSE-STEM-AUTISM ChEA Transcription Factor Targets 2022 1.0 null GSE225218_0_v_3_abcb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59692 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 2.16438 Perturb_17222_KD_SOX2_ERP128142 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_15703_KD_JMJD1A/AGE_SRP353924 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE242367_1_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.15028 KPNSI9S CCLE Cell Line Gene CNV Profiles -1.0 -3.21012 kidney_d HPA Tissue Sample Gene Expression Profiles 1.0 1.55556 POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94173 MDAMB415 DepMap CRISPR Gene Dependency 1.0 2.16037 ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.4065 FOXM1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edema CTD Gene-Disease Associations 1.0 1.04757 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64925 GSE155852_0_v_1_apigenin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4501-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin - Sun Exposed (Lower leg) GTEx Tissue Gene Expression Profiles 2023 1.0 6.43946 SW1783 CCLE Cell Line Gene Expression Profiles -1.0 -2.27176 GTEX-P78B-1826-SM-3P5YX GTEx Tissue Sample Gene Expression Profiles 1.0 1.319 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE125862_2_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30803 CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE123638,GSE123639_3_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846233 GSE63048_11_v_6_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MED8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03675 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_5_v_14_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null TAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47001 Perturb_11062_KO_Jup/Ctnnb1_SRP304535 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.0492 GSE87404,GSE87812_1_v_0_hoxa9_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.849479 PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_downregulated_in_the_low_MEIS1_content_thalamus_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null LBP9 (Tcfcp211) MotifMap Predicted Transcription Factor Targets 1.0 null GSE173911,GSE173917_0_v_1_morc3_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNRPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23911 IMCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.661 H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.929271 ELP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09642 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76511 Congenital Abnormalities CTD Gene-Disease Associations 1.0 1.27966 dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25432 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.6851 intermediate stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24031 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07619 EBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146074_0_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_10326_KO_Shp1_SRP370028 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.18204 GSE139455_2_v_1_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-873 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 shell of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03627 KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.63593 hsa-miR-661 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Perturb_4170_KO_Atp1a2_SRP248220 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.38607 GSE178714_6_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_790_OE_Foxk2_SRP145105 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.161 RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980395 GSE240344_1_v_0_uxs1_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null 18794137-SuppTable1c GeneSigDB Published Gene Signatures 1.0 null GSE158502,GSE158506_3_v_0_fat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE146982_7_v_6_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.78259 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4471 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.872581 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2009 UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_168_KO_Itgb3_SRP305656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.57761 GSE241402_0_v_1_prmt5_human RummaGEO Gene Perturbation Signatures 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.859313 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.824509 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836462 Perturb_6940_KO_Rbm20_SRP403612 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.04943 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23177 EP300_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hepatomegaly CTD Gene-Disease Associations 1.0 1.54086 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 medial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50269 GSE174701_4_v_0_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMRC2 CCLE Cell Line Gene Expression Profiles 1.0 2.07373 E2F1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00645 SKNDZ DepMap CRISPR Gene Dependency 1.0 4.7843 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.1266 Neural Tube Defects CTD Gene-Disease Associations 1.0 1.19279 SRF ENCODE Transcription Factor Targets 1.0 null Parietal foramina DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 TBX3 ChEA Transcription Factor Targets 1.0 null Perturb_15774_KO_Uxt_SRP240277 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -17.7167 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures 1.0 null E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.1486 Hyperplasia CTD Gene-Disease Associations 1.0 1.38298 GSE153871_4_v_2_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE205976,GSE205978_3_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.887791 GSE182179_5_v_4_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830656 GTEX-QV31-0626-SM-447C5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34295 Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE119978,GSE180930_3_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210655_1_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EP300_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46137 NCIH1836 CCLE Cell Line Gene Expression Profiles -1.0 -2.06497 GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-1226-SM-4AT5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.12322 GTEX-P4PQ-1026-SM-3NMCN GTEx Tissue Sample Gene Expression Profiles 1.0 0.861231 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39895 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11375 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26979 Perturb_5309_KD_CDK11_SRP172707 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 15.4441 NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ATP2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37442 GTEX-SUCS-0926-SM-4DM4Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.19938 Periventricular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.10589 Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1206 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Breast cancer GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.4699 isthmic part of the intermediate lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52418 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.85638 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27812 GSE184892_6_v_3_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.2363 Perturb_435_OE_miR1343_SRP066865 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE205316,GSE205317_0_v_1_nrip1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE212299_3_v_0_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCIH526 CCLE Cell Line Gene Expression Profiles 1.0 2.38651 GSE228106_0_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GSE119978,GSE180930_6_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.885409 TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POU5F1-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HMV-II COSMIC Cell Line Gene Mutation Profiles 1.0 null AP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE211151_2_v_4_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE254649_2_v_1_cstf2_human RummaGEO Gene Perturbation Signatures 1.0 null MARCHF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01654 GSE201217_3_v_6_usf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6441 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-V1D1-1026-SM-4JBHE GTEx Tissue Sample Gene Expression Profiles 1.0 1.05532 GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null 8MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.76464 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.0189 TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100534_FWM_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.86257 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03877 CAOV4 DepMap CRISPR Gene Dependency 1.0 2.12215 Perturb_17176_OE_HER2_SRP166112 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-0826-SM-4LVMR GTEx Tissue Sample Gene Expression Profiles 1.0 0.903026 NR0B1 ChEA Transcription Factor Targets 1.0 null ACN COSMIC Cell Line Gene Mutation Profiles 1.0 null CEBPB_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178714_5_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null urinary tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE178714_5_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 1.35921 GSE201882,GSE201883_3_v_4_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5828 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44977 GSE159937_2_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930965 GSE157904_0_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.589794 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OV-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEx Lung 20-29 vs 70-79 GTEx Tissue-Specific Aging Signatures -1.0 -5.99203 GSE160001,GSE160670_3_v_2_lapatinib_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_7054_KO_Tead1_SRP229838 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Perturb_5488_KO_Setdb1/Ring1b_SRP314000 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.87801 CPT1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30552 ATP11B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20815 Perturb_4141_KO_Apoe_SRP131850 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.62248 BTBD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00395 chr1_18481403_C_G_b38 GTEx eQTL 2025 1.0 1.92321 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.913012 EFM19 DepMap CRISPR Gene Dependency 1.0 3.14268 GSE67266_7_v_4_etoposide_mouse RummaGEO Drug Perturbation Signatures -1.0 null KASUMI1 DepMap CRISPR Gene Dependency 1.0 2.03921 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03056 ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE239844_1_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22941 Perturb_13357_KO_Ugcg_SRP352608 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE234340_10_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null nucleus sagulum, deep part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06256 medial part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.41899 GSE95685_2_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39895 SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE100464,GSE100465_1_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null EWS-FLI1-20517297-SK-N-MC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1 Rummagene Transcription Factor Associations 2026 1.0 null GSE171712_0_v_1_scgb1a1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.05202 GTEX-S7SF-0926-SM-4AD4M GTEx Tissue Sample Gene Expression Profiles 1.0 0.954834 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-X5EB-1726-SM-4E3J7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00195 GSE71529,GSE71558_1_v_0_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXM1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.926219 intermediate stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06313 GTEX-SNOS-0526-SM-4DM54 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50512 GSE174498,GSE174500_5_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_11237_KO_Thbs1_SRP164677 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.3139 GSE157904_3_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE143782_3_v_11_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-643 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71628 GSE236454,GSE236456_0_v_1_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17917_KO_Shank2_SRP314506 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.32966 r7 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78967 Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19312 GSE200673,GSE200691_2_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.44493 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MYLA DepMap CRISPR Gene Dependency 1.0 3.3578 GSE210580_0_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69394 SMAD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24896 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01288 Perturb_2816_KD_SUFU_SRP346101 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.13452 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29314 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.93886 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07042 GSE135030_3_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null MAPK1IP1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1182 GSE227592_13_v_3_adar_human RummaGEO Gene Perturbation Signatures 1.0 null 496100388_HIP_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.79871 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE235682_1_v_0_rbl2_mouse RummaGEO Gene Perturbation Signatures 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.867018 NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE214931_3_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null septopallidal core nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42208 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESR1 ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D4-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-P4QS-0526-SM-2I3ET GTEx Tissue Sample Gene Expression Profiles 1.0 0.869963 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3663 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.839504 TMEM86A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31676 HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02357 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE166004_5_v_4_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WFON-0826-SM-4LVMI GTEx Tissue Sample Gene Expression Profiles 1.0 1.28606 mRNA_SALL4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_5338_KO_Haunt_SRP044012 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.48952 EFTUD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20994 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.531 hsa-miR-24 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 intermediate stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08189 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.00879 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.838905 r2 part of prepontine raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33653 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30388 8505C COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S32W-0826-SM-4AD5Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.897967 BL2838 (UIMC1) NURSA Protein Complexes 1.0 null TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25401 GSE111035,GSE111040_8_v_5_plag1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QLQ7-0926-SM-447BC GTEx Tissue Sample Gene Expression Profiles 1.0 0.843058 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0557 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM31 CCLE Cell Line Gene Expression Profiles -1.0 -1.7861 GSE182075_3_v_1_btn1a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE166004_3_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE202587_1_v_0_xrn1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210383_0_v_1_trim71_mouse RummaGEO Gene Perturbation Signatures -1.0 null Weight Gain CTD Gene-Disease Associations 1.0 1.05936 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1092 CCLE Cell Line Gene CNV Profiles 1.0 1.3786 GTEX-VJYA-0826-SM-4KL1M GTEx Tissue Sample Gene Expression Profiles 1.0 0.912668 GSE186316_0_v_1_ccn2_mouse RummaGEO Gene Perturbation Signatures 1.0 null sensory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Rto TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 SEC24B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24712 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S341-0226-SM-2XCAX GTEx Tissue Sample Gene Expression Profiles 1.0 0.848946 Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Plagl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.8477 nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45254 HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA ChEA Transcription Factor Targets 2022 1.0 null GSE139455_7_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RWS6-0926-SM-47JXE GTEx Tissue Sample Gene Expression Profiles 1.0 1.3309 Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27722 Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.02671 Perturb_14325_OE_TIPE2_SRP386829 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.7889 Ventromedial hypothalamic nucleus, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26904 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05464 globe disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.100789 RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.071 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE62843,GSE64370_0_v_1_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE106661,GSE106665_0_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.970423 BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0178 MXI1 ENCODE Transcription Factor Targets 1.0 null Parametrial fat pad TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.969 GSE44157,GSE44163_1_v_0_nr6a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE193751_1_v_3_oridonin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null preopto-hypothalamic band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22702 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.851968 Excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 AU565 DepMap CRISPR Gene Dependency 1.0 2.38089 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null AR ChEA Transcription Factor Targets 1.0 null GTEX-S3XE-1026-SM-4AD4O GTEx Tissue Sample Gene Expression Profiles 1.0 0.968624 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.4057 GSE174498,GSE174500_5_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55898 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null EP300_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE71468,GSE76476_0_v_1_rbfox1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC5630028-supp_gr.220533.117_Supplemental_File_S7.xlsx-TP53_core_genes-Unnamed_1_TP53 Rummagene Transcription Factor Associations 2026 1.0 null NR0B1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.863865 GSE210580_4_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4807-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8350598-NIHMS1728503-supplement-Table_S3.xlsx-Downregulated_by_SMAD4-Gene_Symbol_SMAD4 Rummagene Transcription Factor Associations 2026 1.0 null superior parietal lobule, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.853238 GSE144231_4_v_1_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_GADD45A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SPRYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31653