association	dataset	threshold value	standardized value
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100670_TCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.07249
GIPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77349
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902557
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930962
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
compared	GeneRIF Biological Term Annotations	1.0	null
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97042
KP4	CCLE Cell Line Gene CNV Profiles	1.0	1.45449
cellular_component	GO Cellular Component Annotations 2015	1.0	null
cSARS Bat SRBD_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.2155
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4481
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22327
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.36565
C-type lectin fold	InterPro Predicted Protein Domain Annotations	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13025
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042136
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5014
Perturb_4877_OE_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8516
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NK-92 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.088865
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79447
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Large_Intestine-cd8-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	2.0226
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84269
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
MSMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36099
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2506
manner	GeneRIF Biological Term Annotations	1.0	null
INSR	Kinase Library Tyrosine Kinome Atlas	1.0	97.44
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53095
HNF4A	ENCODE Transcription Factor Targets	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5063
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
PSMB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64333
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63792
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
monomeric	GeneRIF Biological Term Annotations	1.0	null
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.38114
establishment of localization	GO Biological Process Annotations 2015	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00846
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
natural killer cell activation involved in immune response	GO Biological Process Annotations 2023	1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
mbl2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3541
HPDL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57797
Body Height	dbGAP Gene-Trait Associations	1.0	0.066925
RPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32931
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.84846
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.36843
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6316
EW22	DepMap CRISPR Gene Dependency	1.0	3.58967
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904338
HCT15	DepMap CRISPR Gene Dependency	1.0	4.05638
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9195
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847197
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90139
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14005
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11940_KD_SMARCD1_ERP132006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.41212
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
other	GeneRIF Biological Term Annotations	1.0	null
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.81406
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.115
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.898226
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.237
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.62203
leukocyte activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94657
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2364
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69715
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
keratinocytes	GeneRIF Biological Term Annotations	1.0	null
PMC11399095-44161_2024_532_MOESM14_ESM.xlsx-Sheet1-Supplementary_Table_13_DEG_in_the_AA_borderzone_in_AF_vs_SR_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91827
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.166
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903397
Perturb_8656_OE_ESRRG_SRP304240	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
lymphocyte activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.469804
Perturb_8473_Mut|KD_IDH1_SRP099826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.17625
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901585
Mastocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
affinity	GeneRIF Biological Term Annotations	1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30515
abnormality of body height	GWASdb SNP-Phenotype Associations	1.0	0.585507
Acute megakaryoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3776
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2023	1.0	null
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88009
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3112
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83607
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22124
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.58619
structure	GeneRIF Biological Term Annotations	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77458
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88249
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0469
regulated secretory pathway	GO Biological Process Annotations 2015	1.0	null
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	11.5511
kacl	GeneRIF Biological Term Annotations	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62366
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4773
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Perturb_1180_KD_RUNX1_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
A172	DepMap CRISPR Gene Dependency	1.0	4.54761
nkp65expressing	GeneRIF Biological Term Annotations	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3107
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
E2F4	ENCODE Transcription Factor Targets	1.0	null
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.83255
OCI-AML3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.9774
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5292
IRR	Kinase Library Tyrosine Kinome Atlas	1.0	99.65
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3035
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56454
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lymphocyte activation	GO Biological Process Annotations 2015	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00052
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71516
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43677
OVMIU	DepMap CRISPR Gene Dependency	1.0	12.4708
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4915
cell activation	GO Biological Process Annotations 2015	1.0	null
cellcell	GeneRIF Biological Term Annotations	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05412
chr12_9921215_C_T_b38	GTEx eQTL 2025	1.0	1.41965
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
S-layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27975
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
Perturb_4392_KD_RNF5_SRP276909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.64606
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	2.18987
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10336
16140871-SuppTable7	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of cytokine production	GO Biological Process Annotations 2025	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27212
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57756
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
ESR1_T47D_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1667
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
PMC8571097-41588_2021_941_MOESM3_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_List_of_KMT2A_fusion_oncoprotein_target_genes_in_each_sample_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52462
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09033
CUL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4263
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	1.6151
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63383
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
interleukin-15 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.524
ESR1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
PL4	DepMap CRISPR Gene Dependency	1.0	2.66332
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.721
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68408
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903397
single-organism process	GO Biological Process Annotations 2015	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3645
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65284
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34641
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54935
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.56
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
PSS008	DepMap CRISPR Gene Dependency	1.0	4.29202
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1148
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
regulation of cytokine production	GO Biological Process Annotations 2025	1.0	null
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.40955
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08564
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43677
disease	GWASdb SNP-Disease Associations	1.0	0.023819
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896578
T84	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.963498
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59547
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14005
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930962
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85166
exocytosis	GO Biological Process Annotations 2015	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32206
PMC9203705-10.1182-2021014723_bloodbld2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833106
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
GDM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91093
non-Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6342
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922861
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17144
natural killer cell degranulation	GO Biological Process Annotations 2023	1.0	null
SNU81	DepMap CRISPR Gene Dependency	1.0	13.1842
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.9318
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.7205
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51776
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.24616
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.469804
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5655
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA3_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83314
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993595
C80	DepMap CRISPR Gene Dependency	1.0	3.34498
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962647
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.093779
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3099
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886411
LUZP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61949
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7336
protein binding	GO Molecular Function Annotations 2015	1.0	null
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78915
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3218
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24669
RSC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86179
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
natural killer cell mediated cytotoxicity	GO Biological Process Annotations 2025	1.0	null
pairs	GeneRIF Biological Term Annotations	1.0	null
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39739
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38874
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
depression	GWASdb SNP-Phenotype Associations	1.0	0.355772
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25405
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3037
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
CLRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.26
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58217
UACC893	DepMap CRISPR Gene Dependency	1.0	14.2872
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1395
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
TLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98719
natural killer cell mediated cytotoxicity	GO Biological Process Annotations 2023	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.53197
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6326
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992876
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69841
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9369
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
positive regulation of cytokine production	GO Biological Process Annotations 2023	1.0	null
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13426
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78962
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.258672
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24177
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32724
ESR1	ENCODE Transcription Factor Targets	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05412
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.485
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61221
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9939
Cord blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
Perturb_597_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.42057
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33215
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.922861
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60405
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.6312
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76197
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30526
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCT116	DepMap CRISPR Gene Dependency	1.0	2.85128
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
9505BIK	DepMap CRISPR Gene Dependency	1.0	8.74968
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10733
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65918
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CHD2	ENCODE Transcription Factor Targets	1.0	null
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55048
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1149
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13951
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.107
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46492
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.94
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60615
protein secretion	GO Biological Process Annotations 2015	1.0	null
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2713
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8215
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54475
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7582
cell activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43739
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5751
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1844
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14316
GSE193351_4_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27698
capable	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904338
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.38032
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.54112
Car cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77208
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65091
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	0.973941
FOS	ENCODE Transcription Factor Targets	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4012
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
JHU022	DepMap CRISPR Gene Dependency	1.0	6.14353
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72622
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39105
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896578
PMC9203705-bloodBLD2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90446
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7093
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63871
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66886
USF2	ENCODE Transcription Factor Targets	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.08805
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.25
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	1.389
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1149
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	6.13099
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0888
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.166
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33399
MYC	ENCODE Transcription Factor Targets	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896578
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9758
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70858
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07132
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.52827
SW579	CCLE Cell Line Gene CNV Profiles	1.0	2.75444
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78767
Perturb_4909_KD_IMP1_SRP070819	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28846
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
PL4	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
Molluscum contagiosum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992876
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59092
GSE160817_2_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888062
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45236
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993595
GSE140997_10_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07638
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mood disorder	GWASdb SNP-Disease Associations	1.0	0.286115
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27848
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1416
compensate	GeneRIF Biological Term Annotations	1.0	null
stimulating	GeneRIF Biological Term Annotations	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856971
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24906
NCI-H650	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2364
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36419
POLDIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3552
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.837068
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.984
COLO824	DepMap CRISPR Gene Dependency	1.0	4.523
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886411
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9269
C-type lectin	InterPro Predicted Protein Domain Annotations	1.0	null
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08714
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30867
GSE195559_8_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.48737
C-type lectin-like	InterPro Predicted Protein Domain Annotations	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17671
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
natural killer cell activation involved in immune response	GO Biological Process Annotations 2025	1.0	null
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52748
single-organism transport	GO Biological Process Annotations 2015	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56113
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0135
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7486
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930962
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34214
nature	GeneRIF Biological Term Annotations	1.0	null
natural killer cell activation involved in immune response	GO Biological Process Annotations 2015	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3403
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81758
PMC4820104-pone.0152929.s021.docx-0-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08874
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20887
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07188
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.0684
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.75
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85948
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70483
cellular process	GO Biological Process Annotations 2015	1.0	null
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86122
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17614
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935121
natural killer cell degranulation	GO Biological Process Annotations 2015	1.0	null
immune system process	GO Biological Process Annotations 2015	1.0	null
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7137
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
natural killer cell degranulation	GO Biological Process Annotations 2025	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
CABLES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56035
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.48168
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
Perturb_4898_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.5184
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12479
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901585
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24017
express	GeneRIF Biological Term Annotations	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8272
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3645
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17144
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.68704
achieve	GeneRIF Biological Term Annotations	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993595
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17797
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8311
GSE195559_6_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2603
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00272
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.59461
FGFR4	Kinase Library Tyrosine Kinome Atlas	1.0	96.23
RNK-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.9689
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0525
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
RCM1	DepMap CRISPR Gene Dependency	1.0	6.97885
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S10_DGEA_IKZF1-Supplemental_Table_10_Differentially_expressed_genes_between_IKZF1_and_all_other_subcluster_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr12_9935485_T_C_b38	GTEx eQTL 2025	1.0	2.00364
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25653
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84733
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73951
LS1034	CCLE Cell Line Gene CNV Profiles	1.0	2.00098
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7634
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77081
MEL270	DepMap CRISPR Gene Dependency	1.0	5.57297
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	3.80754
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965021
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0578
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13083
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45924
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96586
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24177
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5885
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
AGPAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80033
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41042
secretion by cell	GO Biological Process Annotations 2015	1.0	null
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43212
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49796
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
SKMEL30	DepMap CRISPR Gene Dependency	1.0	2.30136
PMC10758738-BLOODA_ADV-2023-010385-mmc2.xlsx-SuppTable_S6_Classifier_params-HOXA_KMT2A_classifier_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
P-815 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3943
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.75069
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4045
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930962
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77834
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.43835
GZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07103
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35755
FOXA1	ENCODE Transcription Factor Targets	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	1.35508
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
T47D	CCLE Cell Line Gene CNV Profiles	-1.0	-3.18948
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50792
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-ML2_-_MLL-AF6-Non-spreading_targets_gene_names_65_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
JAK1	Kinase Library Tyrosine Kinome Atlas	1.0	96.61
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5014
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.23752
CAPAN1	DepMap CRISPR Gene Dependency	1.0	3.86568
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00109
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14005
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24826
Cytoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.16297
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8959
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL1-CLOSEST_GENE_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
MAFK	ENCODE Transcription Factor Targets	1.0	null
leukocyte degranulation	GO Biological Process Annotations 2015	1.0	null
ESR1-30970003-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52769
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847197
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6088
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03635
NCIH1703	CCLE Cell Line Gene CNV Profiles	1.0	1.63898
KDM5A	ENCODE Transcription Factor Targets	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856971
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63827
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8001
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78152
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.262519
KLM1	CCLE Cell Line Gene CNV Profiles	1.0	1.50446
m07e	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.701
CLDN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93902
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5938
leukocyte activation	GO Biological Process Annotations 2015	1.0	null
natural killer cell activation	GO Biological Process Annotations 2015	1.0	null
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.749
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.03017
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39461
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.76753
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3817
explains	GeneRIF Biological Term Annotations	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
OACM5-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.36169
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69747
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.66347
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3801
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1316
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030211
GSE101467_0_v_1_dock8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3731
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98114
kacldependent	GeneRIF Biological Term Annotations	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9639
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
OVOL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6763
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
GATA3	ENCODE Transcription Factor Targets	1.0	null
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993595
SGSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57488
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82309
transport	GO Biological Process Annotations 2015	1.0	null
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28853
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
carbohydrate binding	GO Molecular Function Annotations 2015	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cytokine production	GO Biological Process Annotations 2023	1.0	null
CWC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61678
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43677
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95794
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
IGF1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.053114
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8703
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73951
cytokine secretion	GO Biological Process Annotations 2015	1.0	null
Mastocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
Myeloid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
SKMEL31	CCLE Cell Line Gene CNV Profiles	1.0	1.76084
RHBDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50831
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7578
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1222
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38083
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35467
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50897
PPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92715
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
secretion	GO Biological Process Annotations 2015	1.0	null
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5016
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2969
LTBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28221
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992876
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3645
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89102
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60629
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
PMC7100912-EMS85677-supplement-Suppl__Tables_1_8.xlsx-Table_6-Supplementary_Table_6_Nanostring_gene_expression_profiling_of_memory_T_cells_transduced_with_BHLHE40_BHLHE40	Rummagene Transcription Factor Associations 2026	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20356
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1159
GSE193351_4_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4325
protein transport	GO Biological Process Annotations 2015	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9558
IA-LM	COSMIC Cell Line Gene CNV Profiles	1.0	2.10992
exceptionally	GeneRIF Biological Term Annotations	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.039179
IALM	CCLE Cell Line Gene CNV Profiles	1.0	2.19052
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00109
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.38032
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.550881
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.38804
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
IGF1R	Kinase Library Tyrosine Kinome Atlas	1.0	98.31
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00068
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9971
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04868
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHHCALL4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48351
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00846
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81978
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49457
immune effector process	GO Biological Process Annotations 2015	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856439
positive regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	2.18786
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.764
STX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435