association	dataset	threshold value	standardized value
protein-lysine N-methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
alvimopan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM106C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44962
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2344
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
5762_NPAT_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.59476
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
Odanacatib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paraspeckles	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7454_RPL27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621552
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
SHREC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UMUC5	DepMap CRISPR Gene Dependency	1.0	2.19244
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.926
GSE205163,GSE205164_3_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of B cell activation	GO Biological Process Annotations 2025	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
LSM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55651
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
HPGDS-In1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
NCIH1755	DepMap CRISPR Gene Dependency	1.0	3.34852
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29794
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5435
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.359
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12079334-ADVS-12-2501734-s002.pdf-197-ENSG00000204604_ZNF468	Rummagene Transcription Factor Associations 2026	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pineocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13743
PMC10646502-Table_1.xlsx-Table_S8-IRF3_Target_genes_according_to_Dorothea_s_TF-TG_network_confidence_A_to_C_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04603
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-SOX2-M_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12928
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1453
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GW 441756	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
Adult astrocytic tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Lung fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
CENP-A containing nucleosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140074_1_v_0_kif20a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.681986
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16288
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC-827 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165689_0_v_1_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_6_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.296
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fetal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
105_ACTG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.825698
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF507	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28396
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.627
GSE124014_0_v_1_nnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dense fibrillar component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
CHOP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.539
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hematopoietic cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10228
DNA damage response	GO Biological Process Annotations 2023	1.0	null
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8345
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
heterochromatin	GO Cellular Component Annotations 2023	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.557
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
G-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.68
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3626
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.62111
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.5933
PMC8384902-mmc2.xlsx-3_ASCL1_high_subtype-Gene_Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
nBAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
NCIH1573	DepMap CRISPR Gene Dependency	1.0	6.83566
Metolazone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
ICC2	DepMap CRISPR Gene Dependency	1.0	2.93594
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.557
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.222
Cleavage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
B-lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28795
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39161
HCC78	DepMap CRISPR Gene Dependency	1.0	7.96245
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE73562,GSE73563_1_v_2_preb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Blood cancer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
PRC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.317
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00765
HDA1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of B cell activation	GO Biological Process Annotations 2023	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
RNA polymerase I upstream activating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein-lysine N-methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.467
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SR 11237	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.22971
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1413
HBL-100 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56053
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
histone H4 methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
Brahma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pons	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.117
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
GSE112860_9_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
RBL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
g2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.057
MDA-MB-361 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0953
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.133
Fluoxymesterone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.29
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65789
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32259
positive regulation of double-strand break repair via nonhomologous end joining	GO Biological Process Annotations 2023	1.0	null
PMC8042281__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
NCO2	DepMap CRISPR Gene Dependency	1.0	6.92758
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55111
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6138666-41398_2018_246_MOESM4_ESM.xlsx-Sheet1-Table_S3_Nominally_significant_ZBTB20_targets_from_association_analysis_of_SAD_versus_healthy_controls_sorted_by_p-value_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Barr body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.666
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
LM3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283112
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24915
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28903
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
N6022	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
HT-1080 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
SCF-Skp2 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
MM160113	DepMap CRISPR Gene Dependency	1.0	8.87455
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18733
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Selisistat	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
6024_PABPC1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512907
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Immunodeficiency with hyper-IgM type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1657
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200464
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2128
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16559
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25747
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.071
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lysine degradation	KEGG Pathways 2026	1.0	null
Rupatadine	DeepCoverMOA Drug Mechanisms of Action	1.0	1.11
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12109
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8641
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WSU-DLCL2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14827
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78098
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Ino80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22249
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72709
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28405
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7696
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3225
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.055
KMS26	DepMap CRISPR Gene Dependency	1.0	2.36125
positive regulation of double-strand break repair	GO Biological Process Annotations 2025	1.0	null
Silmitasertib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.75
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.055
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20394
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53333
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Midbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.061
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
Nucleolus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251907
Erythroid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
TRAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14301
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8723
CHRAC	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.533
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSK429286A	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.69
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nuclear inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.64806
Olaparib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5015
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6997
PMC7927886-2019_239970_BOUSSAID_SUPPL_TABS2.xlsx-GATA1_targets_-_genesets-Unnamed_1_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243893
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
Primary hyperoxaluria type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.692
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.551
MRE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29971
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Myelodysplastic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Methylosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15554
Chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7244323-elife-55325-supp3.xlsx-This_paper_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SWI/SNF superfamily-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.043
PML body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lamin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	7.17176
BAY 57-1293	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
positive regulation of double-strand break repair via nonhomologous end joining	GO Biological Process Annotations 2025	1.0	null
Dosage compensation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of developmental process	GO Biological Process Annotations 2023	1.0	null
Leukemia cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
Urinary bladder transitional cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4322
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6273
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77706
Chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.491
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.046
Primitive endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
PMC8384902-mmc2.xlsx-4_NEUROD1_high_subtype-Gene_Symbol_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of double-strand break repair via nonhomologous end joining	GO Biological Process Annotations 2023	1.0	null
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.3001
MV4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06304
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0125
GAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31319
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-422 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
Trigeminal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75253
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4114
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Progeria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
4946_MED23_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502775
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8951
Embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.834
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_5_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	2.01519
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.16
Nucleus lentiformis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.141
BEST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21965
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RITS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
679_ATP6V1A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.656135
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.057
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6427
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF-268 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6194
Jiyoye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromosomal region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9194
histone H4K20 methyltransferase activity	GO Molecular Function Annotations 2023	1.0	null
Endometrial carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284323
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9436
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INO80-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.979
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T-cell chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PSMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1588
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11269579-41598_2024_67843_MOESM1_ESM.pdf-76-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
MCMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08431
CCC5	DepMap CRISPR Gene Dependency	1.0	4.58441
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
4270_KANSL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.531517
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20957
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11182
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
Lymphoblastoid cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2074
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214237
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
PcG protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.063
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1736
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46454
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.675
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512872
PMC8042281__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A-196	DGIdb Drug Targets 2026	1.0	26.466
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
6890_PSPH_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.593752
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40719
GSE198165,GSE198166_7_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.391
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1348
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37506
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46501
PMC4909395-elife-13964-supp1.xlsx-Sheet1-Supplementary_file_1_shRNA_screen_hits_selective_to_ERG-positive_prostate_cancer_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02551
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.035
1966_CUL7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.575787
PMC11297914-41389_2024_531_MOESM1_ESM.pdf-228-ZNF277_ZNF277	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
Inner kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
GSE128333_3_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE244072_4_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Menopause (age at onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31523
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of DNA recombination	GO Biological Process Annotations 2023	1.0	null
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.675
Ophthalmic nerve	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1379
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216412
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5692555-pnas.1708341114.sd04.xlsx-3TFs_no_GATA2-gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Fibrosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6498
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37498
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sin3-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.096
PMC11151076-ADVS-11-2306486-s002.xlsx-TSPYL1_FOXA1_targets-DDB2_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4327
KPNYS	DepMap CRISPR Gene Dependency	1.0	12.1178
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197197,GSE212981_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cytotoxic T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.057
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29886
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rpd3S/Clr6-CII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5035
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
Peripheral ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
PMC9882185-media-2.xlsx-Ctrl-specific_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7428
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8244
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.56158
Tolimidone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13368
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Basophilic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
NCIH2052	DepMap CRISPR Gene Dependency	1.0	5.69451
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5762
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.7136
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
PMC10534007-Table_2.xlsx-S1_overlap_MSC_up_B_V-438_common_elements_in_BFTC905_MSC_up_and_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
MLL1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89188
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69372
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06251
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05328
Erythromycin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.84371
IMR32	DepMap CRISPR Gene Dependency	1.0	5.31911
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6045
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
NCIH446	DepMap CRISPR Gene Dependency	1.0	3.15527
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NuA3 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoblast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
pre-replicative complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.179
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dinoprost	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55518
DNA damage response	GO Biological Process Annotations 2025	1.0	null
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44182
C-643 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
Lymphocytic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
positive regulation of isotype switching	GO Biological Process Annotations 2025	1.0	null
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14243
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.949923
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81729
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.30206
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.608
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HAC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60619
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alfuzosin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.67
PMC9882185-media-2.xlsx-All_B2-AR_targets-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_ATF1-gene_ATF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186483_6_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4796
T-lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
TOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35002
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28568
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24215
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3773
chromosome, centromeric core domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
PMC9882185-media-2.xlsx-Ctrl-specific_B2-AR_targets-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0175
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188832,GSE188835_0_v_1_irf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal dominant intellectual developmental disorder 51	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.403
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.927
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31148
Progeroid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cranial nerve	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.956
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60558
DNA replication and repair system	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2906
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Spinal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
Lymphoblastic leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4953_MED30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.681159
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.97
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73383
positive regulation of immunoglobulin production	GO Biological Process Annotations 2023	1.0	null
Wolf-Hirschhorn syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
pericentric heterochromatin	GO Cellular Component Annotations 2023	1.0	null
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12149
MOLM13	DepMap CRISPR Gene Dependency	1.0	2.46652
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44717
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
marc145	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
CHD-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.98
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03569
UMUC16	DepMap CRISPR Gene Dependency	1.0	2.31996
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07739
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.827
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
LNCaP-AI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8836
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.057
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC4889920-supp_gkw096_nar-03505-x-2015-File018.xlsx-Target_genes_per_GO_class-ZNF57_ZNF57	Rummagene Transcription Factor Associations 2026	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
L428	DepMap CRISPR Gene Dependency	1.0	3.05645
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rpmi1788	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.284
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7976
AT 406	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249803
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24395
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3654
immunodeficiency-centromeric instability-facial anomalies syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
RERF-LC-AI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
PanIN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.427
GSE196407_1_v_0_fluorouracil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8042281__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Chromatin organization	Reactome Pathways 2024	1.0	null
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26568
NCIH1993	DepMap CRISPR Gene Dependency	1.0	2.02857
regulation of isotype switching	GO Biological Process Annotations 2023	1.0	null
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
U2-OS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
Kleefstra syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
positive regulation of double-strand break repair	GO Biological Process Annotations 2023	1.0	null
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59958
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21095
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
Endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.029
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34267
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9308
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54763
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
4148_INTS3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.613264
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Syndromic X-linked intellectual disability Claes-Jensen type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.806919
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
RNA polymerase II, holoenzyme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35614
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38495
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
Snt2C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4686
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6786
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.942
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249886
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26293
Cysmethynil	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02772
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02418
GSE235066_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pamoic Acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.6
regulation of isotype switching	GO Biological Process Annotations 2025	1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
NTERA-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7589
Origin recognition complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.657
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Histone modifications	WikiPathways Pathways 2024	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Subtelomeric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Chronic lymphocytic leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	2.54205
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
OSI-027	DeepCoverMOA Drug Mechanisms of Action	1.0	0.83
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67015
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.47779
PMC12583649-41419_2025_8086_MOESM11_ESM.xlsx-Sup_Table_4-Supplementary_Table_4_Mean_Influence_MI_of_regulators_in_DMSO_Capmatinib_or_Trametinib_treatment_under_HGF_stimulation_conditions_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of immunoglobulin mediated immune response	GO Biological Process Annotations 2025	1.0	null
Globus pallidus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.141
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27202
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126621,GSE126920_1_v_3_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
GSE192689_0_v_3_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265429
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.8606
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02274
GSE205163,GSE205164_9_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-11/TKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.513
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06842
GSE147210_3_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11092
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Omega speckle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08593
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1082
GSE223008_5_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14629
pericentric heterochromatin	GO Cellular Component Annotations 2025	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12129
DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Blonanserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.75
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.07482
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	2.72416
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
HT1376	DepMap CRISPR Gene Dependency	1.0	3.77178
ESC/E(Z) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.039
PMC12661842-13018_2025_6493_MOESM5_ESM.pdf-7-KDM2B_KDM2B	Rummagene Transcription Factor Associations 2026	1.0	null
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85732
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10329
chromosome, telomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	215.545
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.172
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61438
MOLM14	DepMap CRISPR Gene Dependency	1.0	9.0647
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75389
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Trigeminal nerve	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Lorcaserin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.34
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_BMS-536924_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105929
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
chromosome, centromeric region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
positive regulation of DNA recombination	GO Biological Process Annotations 2025	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.651
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.438
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
histone methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1579
MM253	DepMap CRISPR Gene Dependency	1.0	5.66125
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4595
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
SF3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47493
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17354
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
Sitaxsentan	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
GSE195568_2_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7477_RPL7A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.29323
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248859
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1786
Vicriviroc	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
8680_TANGO6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.733208
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_TEAD2-gene_TEAD2	Rummagene Transcription Factor Associations 2026	1.0	null
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0009
Heterochromatin domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.573
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.08646
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sulfanilamide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.22
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
GSE160246_9_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Calu-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.072
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57326
Tiplaxtinin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120595_0_v_1_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Larynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54942
positive regulation of immunoglobulin mediated immune response	GO Biological Process Annotations 2023	1.0	null
Nuclear speck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212287
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	3.01157
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heterochromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Pericentric heterochromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
SHREC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.88
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
FOXQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52933
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11167
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48773
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6466304__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
Super elongation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FACT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.98
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52869
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
Cerebral peduncle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.061
GSE87404,GSE87812_1_v_3_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3962
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03872
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Telomerase catalytic core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.533163
Adrenal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.114
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8957
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE254517_3_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
Levosimendan	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
Leukemia cell line	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52792
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46984
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NURF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2778
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1166
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.13555
positive regulation of developmental process	GO Biological Process Annotations 2025	1.0	null
Nerve	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
IMR-90 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
BRCA1-BARD1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
histone H4K20 methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
33B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6597
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1688
CAY10650	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
RNA polymerase I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.623
SVGp12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03212
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
NuRD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.982
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
Fibre tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.061
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15657
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
GSE255988_2_v_0_ethanol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RSC-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.104
8MGBA	DepMap CRISPR Gene Dependency	1.0	3.48869
CENP-A recruiting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.7954
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.818
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04918
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9006
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Nucleolar ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
REEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35239
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272632
ABT-737	DeepCoverMOA Drug Mechanisms of Action	1.0	0.45
TE6	DepMap CRISPR Gene Dependency	1.0	5.45965
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.32148
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13791
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3007
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1852
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
5344_MTRNR2L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.686486
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6411
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7854
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270735
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5169
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chromatin modifying enzymes	Reactome Pathways 2024	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_Cal62_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
LNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35106
JHU011	DepMap CRISPR Gene Dependency	1.0	2.4471
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1188
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.92
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19114
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44819
Helper T-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.051
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.551
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G-401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4058
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13532
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.249
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_baboon_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Breast cancer stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42854
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57156
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200687,GSE200688_1_v_0_sox15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MB21D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65918
Histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.371
7516_RPS27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.568763
ISWI-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
positive regulation of isotype switching	GO Biological Process Annotations 2023	1.0	null
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WI-38 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.137
Dyschromatosis universalis hereditaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of immunoglobulin production	GO Biological Process Annotations 2025	1.0	null
Cranial ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.027
SWI/SNF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
ZBTB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19589
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACE1_In	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143512,GSE143513_0_v_1_nr4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
GSE198165,GSE198166_0_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
APPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05128
Actin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tipifarnib	DeepCoverMOA Drug Mechanisms of Action	1.0	0.53
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.7517
GSE144231_6_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
histone H4 methyltransferase activity	GO Molecular Function Annotations 2025	1.0	null
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-56-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.645
DNA repair	GO Biological Process Annotations 2025	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38992
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4931
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Euchromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
Pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.029
SNU182	DepMap CRISPR Gene Dependency	1.0	3.54331
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1857
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.286
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
CAY10683	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.24
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.093
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96188
MSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
Ibutamoren	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.57
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
7607_RUVBL1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.512264
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.433
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
PMC12188705-msphere.00110-25-s0007.pdf-100-THAP7_THAP7	Rummagene Transcription Factor Associations 2026	1.0	null
Granular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
Perinucleolar compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01081
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sotos syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.949
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
BRCA1-A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6466304__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4021
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186483_1_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.992
Interchromatin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6592
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11389
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20014
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32406
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251643
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9529
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
GSE140651,GSE140653_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252726
NCI cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
EKVX cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7614775-EMS178742-supplement-Proteomics_Table_2.pdf-249-SETDB1_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
THP1	DepMap CRISPR Gene Dependency	1.0	5.47473
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
Nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.166
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.163
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
ML349	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
skmel24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250423
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF862	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30003
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_6_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-150 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.77485
regulation of double-strand break repair via nonhomologous end joining	GO Biological Process Annotations 2025	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
B-lymphoblastoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03408
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.072
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.16685
GSE131649_4_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNA repair	GO Biological Process Annotations 2023	1.0	null
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.684
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4368
PMC7244323-elife-55325-supp3.xlsx-Haapaniemi_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
Osteoarthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.495
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7244323-elife-55325-supp3.xlsx-Noordermeer_TP53-KO-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
1351_CCT7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.643789
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE146074_1_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
MOLT-4 cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
Nucleolar chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.39
PMC8042281__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
GSE152432_1_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3564263-msb201265-s10.xls-Up-regulated-ARID5B_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.512613
Uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
PKMTs methylate histone lysines	Reactome Pathways 2024	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51219
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-encode-consensu_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
DNA metabolic process	GO Biological Process Annotations 2023	1.0	null
Meier-Gorlin syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8186
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.024
CENP-A containing chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
PMC9691391-7945884.f3.pdf-186-ENSG00000140993_TIGD7	Rummagene Transcription Factor Associations 2026	1.0	null
5770_NPM1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.668897
senescence-associated heterochromatin focus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.444
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.116
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.127
PMC3590650-bjc2012518x7.xls-Sheet1-Supplementary_Table_S3_list_of_predicted_target_genes_for_miR29c_present_in_both_PITA_and_Targetscan_predictions_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54522