association	dataset	threshold value	standardized value
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22893
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.06004
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19809
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19026
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54937
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923533
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A_02_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.10434
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00069
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.28326
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COMMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03588
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02221
Vilazodone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11885
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57204
large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5627
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6603-0104	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Perturb_6252_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.5752
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94477
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37405
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23217
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1314
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64496
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26617
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Allergic disease (asthma, hay fever or eczema)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1267
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6956
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_01_324	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60268
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17122
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11618
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37208
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06174
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26581
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836067
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02341
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96289
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06679
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.078553
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36398
GTEx Esophagus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	8.49907
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
NB1	DepMap CRISPR Gene Dependency	1.0	2.31131
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53277
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51474
PMC10794847-mmc2.xlsx-PBRM1_KD_down-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76602
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41943
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6782
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08439
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00062
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910441
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57884
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922531
CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19738
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09885
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16128
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949571
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
PMC12211054-spectrum.00100-25-s0002.pdf-13-ZNF331_ZNF331	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01686
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985506
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39708
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915436
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9431
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8272
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13572
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14251
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32419
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11086
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34858
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4943
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.66914
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09247
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912283
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9929
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75498
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45165
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
LU99	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60462
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55251
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54492
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60691_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.39673
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9878
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0461
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910342
GTEx Testis 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.27573
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42284
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.99868
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65992
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47519
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3103
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siYAP_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07627
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8571
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37625
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1236
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984469
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21245
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64687
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97738
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907611
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12103
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81402
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25464
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8682
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75222
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15826
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2508
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86631
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29836
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.5822
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65449
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847142
ZNF610	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44176
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17916
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39665
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2666
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2548
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07676
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	CCLE Cell Line Gene Expression Profiles	1.0	1.40272
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86328
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85535
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17713
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240497
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.998
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857649
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04308
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03869
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.85458
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80156
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57681
hsa-miR-4525	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.93762
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6958
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FED48h_vs_D2FAST48h_968_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44043
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0461
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8585
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864668
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905185
PX-12	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.61
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98608
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95521
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.92625
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6377
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01411
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837583
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10511
Pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
T84	DepMap CRISPR Gene Dependency	1.0	2.17922
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85177
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12079
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0675
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
GSK4112	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Patent ductus arteriosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08047
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922705
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2414
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858497
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7485
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0123
SYNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86415
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82717
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899483
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49322
null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58459
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.958082
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4995
JQ-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.3
Nonsyndromic congenital nail disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928861
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11975
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892473
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13492
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28399
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1281
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.51201
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04075
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58232
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909064
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901448
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924325
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64784
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07292
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34455
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27907
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869192
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926234
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59293
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52133
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11418
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58923
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5245798-pgen.1006538.s023.xlsx-Sheet1-HOXA2_HOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11129
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Ileus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56883
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37117
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45239
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27085
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41686
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05857
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.26725
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9849
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08927
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5973
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.957324
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91451
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89985
AS-605240	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924329
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.782
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839984
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30104
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27541
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0535
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59807
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11457
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13543
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.30628
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30346
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00304
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17093
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
GSE209601_2_v_3_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26822
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7134
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7396
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46691
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17227
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26503
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44248
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39091
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874045
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29228
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52318
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00062
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.40505
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.74571
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51798
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948799
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2992
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.02315
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77244
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58665
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99812
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15004
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0926-SM-47JXZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914686
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825929
hsa-miR-4762-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08145
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36099
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40242
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3704
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2956
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68214
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04623
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30244
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00202
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964467
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.08394
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36652
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.34767
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05027
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24468
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858664
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36784
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9325
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568823
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35859
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84124
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4719
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831005
Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30674
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944822
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850792
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
NCIN87	DepMap CRISPR Gene Dependency	1.0	5.01248
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19484
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0015
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.49608
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927275
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21245
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86142
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65175
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47878
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
H zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99742
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7623
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4535
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07615
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93274
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
hsa-miR-371b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
RO495	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.88
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46522
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07393
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903281
ELF1	ChEA Transcription Factor Targets	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3719
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37145
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.945436
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04769
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15227
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869275
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22444
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990811
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03331
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
NELFE	ENCODE Transcription Factor Targets	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925818
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30467
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96702
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7643
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00825
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.972594
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3598
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04558
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17234
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10243
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848186
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54633
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9565
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32659
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86292
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40896
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80124
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.61397
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911299
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10462
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	3.63212
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86714
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952623
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7793
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20912
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894026
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.46281
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36897
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929879
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.863187
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907411
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1566
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28332
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86946
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6446
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87428
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965213
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4893
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887611
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86249
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28692
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AM 630	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	1.70684
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87302
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842002
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31414
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55097
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17638
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93347
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4381
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12279
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.83548
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37624
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09114
RBPJ	ChEA Transcription Factor Targets	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38648
KDM5A	ENCODE Transcription Factor Targets	1.0	null
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37899
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937044
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0027
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37568
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34517
skin	GTEx Tissue Gene Expression Profiles	1.0	1.17725
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20852
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83275
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK2334470	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.64
intermediate filament	GO Cellular Component Annotations 2015	1.0	null
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63417
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8226
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_02_198	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.8365
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39808
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01756
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977079
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4037
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19588
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2553
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975832
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2081
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841601
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92186
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
4-Benzylpyridine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92895
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83117
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994272
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94459
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831125
KYAE1	DepMap CRISPR Gene Dependency	1.0	10.8333
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.45814
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_16604_KO_Phb_SRP229743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45143
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00584
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30921
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62768
Prostate adenocarcinoma_PRAD_TCGA-G9-6385-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05165
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039359
GLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81605
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06077
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0455
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8423
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.33381
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47094
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984469
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8394
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4861
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19596
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
SMC3	ENCODE Transcription Factor Targets	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12984
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59565
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934544
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
White sponge nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980038
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26722
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3875
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33396
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12993
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0962
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61779
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7164
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.75541
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25656
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976124
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80004
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826665
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3255
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82237
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2543
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864625
Intestinal pseudo-obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911791
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00365
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4199
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
cell part	GO Cellular Component Annotations 2015	1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	2.71406
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49073
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12027
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20934
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873066
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855275
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7724
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4774
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24112
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70132
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42981
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93017
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9961
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28159
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95364
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13669
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30018
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12727
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.63755
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79458
C32	DepMap CRISPR Gene Dependency	1.0	2.91361
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915376
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07843
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6165_KO_Tet2/Tet3_SRP060364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.35091
adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75775
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4126
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05549
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10579
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57781
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949571
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31605
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71671
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874212
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92267
Asthma or allergic disease (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52626
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15533
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834721
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3719
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01102
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.26176
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0075
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4883
PPARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13152
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01831
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06545
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88578
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860346
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999661
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
A4FUK	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75482
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39139
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31171
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84273
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912071
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7465
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38642
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35904
SW626	DepMap CRISPR Gene Dependency	1.0	4.39537
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76153
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34687
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35425
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46705
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7895
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893565
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0836
OSRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.81343
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27615
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039007
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48693
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45408
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11833
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0908
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE195559_0_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Moh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840033
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978194
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92687
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32141
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2198
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26638
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.1676
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Stipe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836285
hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6999
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
Monilethrix	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05016
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20736
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826378
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93496
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10457
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91236
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85895
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25892
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997803
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24892
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14565
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909422
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01455
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89392
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30759
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78238
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
TMN 355	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.91
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05391
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0079
U2OS	DepMap CRISPR Gene Dependency	1.0	2.47024
rectum	HPA Tissue Protein Expression Profiles	1.0	1.0929
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9318
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17614
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12945
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976165
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10426
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5361
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246716_0_v_1_trappc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60719
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09412
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31129
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9982
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24093
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32285
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9452
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.4211
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06278
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08627
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5373
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3392
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00771
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	241.352
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1925
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58665
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963111
Congenital epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0887
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35302
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937051
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29972
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07183
MONOMAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71812
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3482
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01282
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06672
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34574
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939791
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4315
Chorionic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
ATF7IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03589
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887685
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16643
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5477
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14261
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35622
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9625
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05879
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23171
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7801
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67638
A2780	CCLE Cell Line Gene Expression Profiles	1.0	1.55386
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.57151
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15324
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.915719
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.49699
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08221
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40629
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.839358
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17427
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14544
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4832
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.996837
Varespladib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64687
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20754
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67094
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05794
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11315
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908242
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15702
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.49562
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90497
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0247
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.910874
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72686
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2791
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1668
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41651
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96372
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88274
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0136
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13217
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCA1	DepMap CRISPR Gene Dependency	1.0	2.29797
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32123
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06137
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88694
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86776
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9234
ABL1_mutant_24_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.38505
TR-14035	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.89156
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65268
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.63013
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79814
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12219
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Anagrelide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58249
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09561
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04249
Trunk kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52171
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21511
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKN3	DepMap CRISPR Gene Dependency	1.0	2.68868
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0219
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39633
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49906
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1396
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93746
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.832664
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959405
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.65708
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861747
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D4REFED48h_750_AR--Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40062
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07285
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41333
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.947949
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68166
sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19163
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20341
HNRNPH1_02_08	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12928
Epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7605
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05152
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14846
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64408
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02779
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6833
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_5_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043395
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07191
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6568
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18064
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.87447
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053196
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97437
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995047
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91514
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.663
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11799
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05652
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828072
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23801
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4767
C1orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07171
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62929
PMC3639976-pone.0063011.s017.xls-DataFrame-Dataset_S3_Microarray_analysis_of_HeLa_cells_treated_with_si-PPARD_in_the_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953896
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00008
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07837
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20197
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51029
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Type I terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874404
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92484
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91927
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922573
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23268
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09585
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37334
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850898
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06528
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21689
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37821
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5375
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30907
GATA3	ENCODE Transcription Factor Targets	1.0	null
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5731
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4092
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850898
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61477
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.0929
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998647
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74643
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34034
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	2.06814
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sartorius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14219
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054297
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41262
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67982
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20174
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01927
CHD2	ENCODE Transcription Factor Targets	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05928
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20056
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44162
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0835
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26371
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
u2197	HPA Cell Line Gene Expression Profiles	1.0	1.15275
JUND_02_16	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.11548
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4502	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995995
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55184
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23492
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60122
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95885
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08823
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07478
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	4.51864
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86481
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57024
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885239
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895008
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54136
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8902
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54241
Gingival overgrowth	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66836
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057211
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1938
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057085
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.149
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884425
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39011
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15719
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36054
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12521
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78608
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923569
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19545
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42676
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77013
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97219
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72011
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26328
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72195
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13445
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00357
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22583
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824392
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94148
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28333
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927448
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.44875
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.839066
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10056
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05092
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
Guanethidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
DMS114	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47372
gallbladder	HPA Tissue Gene Expression Profiles	1.0	0.880131
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5215
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57316
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08975
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Keratin, type I	InterPro Predicted Protein Domain Annotations	1.0	null
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70848
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0059
HCC2998	DepMap CRISPR Gene Dependency	1.0	10.0118
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16862
GSE228413_2_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976062
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24965
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06094
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8059
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5538
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880718
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869479
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911637
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14191
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941378
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112707
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78821
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1345
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.37345
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3157
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04894
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02595
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03472
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051525
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912941
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	2.42162
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1106
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939755
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06291
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78332
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3052
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3737
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22997
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97268
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84757
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45098
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918433
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE212762_1_v_2_smarcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72776
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00912
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054751
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68702
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2249
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66536
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.81459
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	1.95767
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04026
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2539
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01396
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09912
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NF-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44549
Cetrorelix	DeepCoverMOA Drug Mechanisms of Action	1.0	0.47
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12593
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7939
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982132
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938451
JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.74449
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56269
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7221
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825405
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88141
Terazosin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06215
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45016
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.290565
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01896
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980096
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4665-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7559
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.43728
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18449
Conjunctival degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78593
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR0B1	ChEA Transcription Factor Targets	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13193
Volasertib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.22
YY1	ENCODE Transcription Factor Targets	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2539
cellular_component	GO Cellular Component Annotations 2015	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08999
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45107
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21368
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36818
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3912
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900301
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
PMC12430004-ugae028_Supplemental_File.pdf-9-IKZF3_IKZF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17778
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39826
Foramen magnum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955211
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8137
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64534
Trihydroxyisoflavone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81403
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5072
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.727711
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503141
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16953
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70411
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46759
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861709
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966363
PMC3712200-584604.f1.pdf-44-SPDEF_SPDEF	Rummagene Transcription Factor Associations 2026	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29347
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18086
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78145
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2756
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835946
Perturb_7062_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.0088
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25878
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16819
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
Necrosis	CTD Gene-Disease Associations	1.0	1.23775
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33292
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26102
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4074
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11435
GTEX-W5X1-2626-SM-4LMI8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1697
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56144
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95111
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83197
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337808
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977744
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29898
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16163
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68563
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6985
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86749
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964967
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19726
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45348
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17056
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12528
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18018
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4257
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12012
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10083
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92946
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06925
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19408
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839237
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4813
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894154
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3701
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01023
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852895
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29957
POU5F1	ChEA Transcription Factor Targets	1.0	null
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23234
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13535
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44922
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848533
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.62377
SNU46	DepMap CRISPR Gene Dependency	1.0	2.73123
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852259
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20592
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823917
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16875
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80614
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46698
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56182
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0162
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5711
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899345
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98537
Blonanserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.61
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1682
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95923
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875537
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	2.73869
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79452
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51146
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02011
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82983
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43227
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.156
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43094
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41197
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51944
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53364
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859802
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_13513_OE_Card11_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.30614
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8215
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57386
Type III polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51527
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-13.9843
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79662
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.377
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34691
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62852
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864979
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827277
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30507
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	2.77729
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65743
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.61897
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964723
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.86405
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994781
JTE 013	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Basal node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5288
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1474
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26958
GSK2656157	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59252
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79619
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51586
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24447
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08569
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4629
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835459
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28164
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9892
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08806
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31171
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46126
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57864
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
RBM25_02_166	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.338
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02055
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8176
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.09314
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924689
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8214
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976237
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04694
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42538
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4261
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985023
Pinguecula	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848256
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
JVM3	DepMap CRISPR Gene Dependency	1.0	4.42618
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33086
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18645
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13089
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21365
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8887
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09584
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948791
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30458
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14846
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.03224
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02891
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76296
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8004
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847321
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07126
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39679
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40168
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04665
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01525
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02187
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5116
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82428
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77885
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72602
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901604
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30406
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03842
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35637
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
SNU16	DepMap CRISPR Gene Dependency	1.0	2.52272
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15779
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7383
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
A 438079	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6204
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29569
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86719
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851424
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848092
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00597
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01896
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23061
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46727
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2688
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35183
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05943
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.645
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.415
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15876
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13345
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26406
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38457
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36448
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9344
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63999
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974265
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18198
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.44876
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.25992
EWSR1	ChEA Transcription Factor Targets	1.0	null
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.46253
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.13936
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01864
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.598
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856116
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9695
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SLC18B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78651
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996749
intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6602
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26368
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21427
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57458
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1523
Burn wound healing	WikiPathways Pathways 2024	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849165
CAPAN2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53492
Genistein	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30304
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.02997
hsa-miR-1275	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.8
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63517
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04171
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08895
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17793
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55428
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41191
Perturb_16827_KO_MLL4_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.09295
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.7224
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34828
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949012
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51314
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3942
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6737
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20979
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01166
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25832
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5622
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diverticulitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78921
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0711
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33211
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81961
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tick infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44742
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49182
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838449
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.0362
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70665
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41757
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936385
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50579
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31467
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01987
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74625
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4466
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9374
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861519
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59831
HT1376	CCLE Cell Line Gene Expression Profiles	1.0	1.4992
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01641
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2105
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1096
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1901
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23729
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1899
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4444
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998775
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14429
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8594
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02187
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2611
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21161
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01131
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61482
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82676
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904862
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00016
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55642
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.57823
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5498
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904184
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87305
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09394
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33356
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4713
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864367
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84647
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31811
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TWIST1_01_253	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59509
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02614
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74382
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01221
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82609
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	4.65835
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29614
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0276
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26089
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91152
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42658
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81466
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88225
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2912
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5061
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67095
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.509
OCUBM	DepMap CRISPR Gene Dependency	1.0	14.6073
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31145
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3-M syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40374
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044634
HS172T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5805
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08287
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99626
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLPP_KO_GDS4791_376_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45892
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81384
EWP-815	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Perturb_14724_KO_Dicer_SRP082704	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4416
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.862445
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52194
CLPP_KO_GSE40207_399_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2329
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843828
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72182
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25125
PLCPRF5	CCLE Cell Line Gene Expression Profiles	1.0	1.6301
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2253
mpkCCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47427
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970397
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7006
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32331
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06006
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42177
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943055
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15504
Ruboxistaurin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53629
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78344
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38727
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31928
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1456
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48821
Cerebral arteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28812
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71812
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85145
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885922
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PF-04418948	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11833
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44545
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5284
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07285
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95977
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0494
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43302
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66723
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39581
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855111
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9701
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96724
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42444
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
mp14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74682
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913403
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2208
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98365
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905292
KE37	DepMap CRISPR Gene Dependency	1.0	2.48609
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7913
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54986
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06943
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80036
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D1FED24h_vs_D1FAST24h_259_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18086
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929303
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22071
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964565
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34973
Perturb_14916_KO_Cd2bp2_SRP034660	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.86358
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0096
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837693
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16506
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69994
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	1.64116
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98537
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7463
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21937
ROS50	DepMap CRISPR Gene Dependency	1.0	2.25948
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24468
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30229
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23348
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58615
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7293
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01196
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14544
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04459
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971546
Perturb_1213_KO_Zfp580/Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.60378
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55687
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62685
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979051
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56394
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99308
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1251
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943743
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35333
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5765
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82795
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.36739
CALU-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48156
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.585
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083082
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07279
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal volvulus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3158
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51569
SYNCRIP_02_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09946
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eukaryotic translation elongation factor 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59565
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64428
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43176
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0783
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49198
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24581
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39328
TOV21G	CCLE Cell Line Gene Expression Profiles	1.0	1.65689
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05902
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46776
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24261
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34977
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.783972
NIBR189	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3698
STAT1	ChEA Transcription Factor Targets	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978736
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05198
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50404
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7942
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978733
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27525
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06094
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1098
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3373
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
XCT 790	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868558
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91832
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79313
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08806
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907594
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
TE6	CCLE Cell Line Gene CNV Profiles	1.0	2.66863
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0104
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1183
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16283
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20088
Intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
SW1990	DepMap CRISPR Gene Dependency	1.0	5.3262
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86141
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.42603
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897604
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2335
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84634
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941845
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
CUX1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0438
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.916607
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI-34051	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85121
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15662
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55837
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954373
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3232
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052404
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7092
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898034
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61188
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.0929
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45506
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27796
Adenosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08653
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02729
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02376
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.926
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66674
KLF1	ChEA Transcription Factor Targets	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46906
Intermediate filament protein	InterPro Predicted Protein Domain Annotations	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35639
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830938
KIJK	DepMap CRISPR Gene Dependency	1.0	3.96897
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82294
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6944_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26721
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0237
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	3.65944
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988768
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16564_KD_Eda_SRP110814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31177
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21349
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08874
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00202
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14771
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.954702
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68999
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2003
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62591
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843708
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
RBBP5	ENCODE Transcription Factor Targets	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92373
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93662
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843282
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01922
ARID3A	ENCODE Transcription Factor Targets	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1775
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51222
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92054
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80739
GSE231799_3_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94972
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.64908
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24644
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11721
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07191
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28296
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.365
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Papaverine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8364
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.44081
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15075
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50161
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07279
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1119
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21451
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9747
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
protein complex	GO Cellular Component Annotations 2015	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94424
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2294
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988363
Olopatadine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879212
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0061
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3818
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79732
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03671
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68603
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32001
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885405
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.77293
Nonsyndromic congenital nail disorder 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4333
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0568
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5237
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69873
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.76247
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0451
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08493
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4728
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16564
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68769
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8567
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1813
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
CLPP_KO_GDS4791_541_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06207
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.913609
RERFLCSQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79878
hsa-miR-3650	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65513
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.85699
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26881
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06458
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22436
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89358
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2449
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3227
organelle part	GO Cellular Component Annotations 2015	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10348
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95762
SKLU-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028752
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06078
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40017
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01492
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adrenal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02262
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58036
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86451
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42702
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59601
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99893
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.236
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132956
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6763
HOXA9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1351
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11987
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58711
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41364
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07911
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97373
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.37398
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32629
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62187
GSE148066,GSE157787_8_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Huntington's Disease_Brain_GSE3621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.95825
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7498
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84378
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90477
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25179
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02577
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19727
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.56962
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8393
ID1_01_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58664
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01584
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08004
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6358_KO_NumbL_SRP307901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.83489
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828855
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03293
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.23054
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66602
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4234
Pomalidomide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.10557
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12933
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0799
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05307
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3796
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84572
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26519
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24723
ASPC1	DepMap CRISPR Gene Dependency	1.0	3.68137
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	1.45381
Alfuzosin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921483
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994681
MRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15532
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38081
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2248
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34451
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49458
Timapiprant	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854358
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849051
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874837
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936755
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38375
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830005
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64569
Perturb_7030_KO_Erg|Fli1_SRP402910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887695
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07419
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM15_02_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01316
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6307
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42008
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11209
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8114
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08181
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11718
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.88818
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4572
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34306
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7864-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47547
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890364
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04132
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48479
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824736
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920768
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948639
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90776
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24826
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.4221
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02605
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39696
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52171
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52941
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31235
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38189
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08518
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0247
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JUN	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.82684
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.3587
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04601
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861531
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SC 560	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84806
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03252
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992931
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45965
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71141
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86245
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7853
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96123
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36969
RAD21	ENCODE Transcription Factor Targets	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7122
Cognitive decline rate in late mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3053
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1542
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847145
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52202
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8013
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72003
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1903
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16351
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48764
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11648
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.90155
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.73005
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11279
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73B-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839696
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.981124
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837545
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958034
Yohimbine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64305
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223378_1_v_0_tead3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8791
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0485
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11484
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02941
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05827
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32868
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3026
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039414
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2967
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924429
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.85185
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2806
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17768
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Guanfacine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CFPAC1	CCLE Cell Line Gene CNV Profiles	1.0	1.39449
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87114
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86011
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.09801
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28217
hmc1	HPA Cell Line Gene Expression Profiles	1.0	2.54962
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16613
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12716
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845026
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40434
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05201
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74923
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01697
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62648
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parasitic ectoparasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.030588
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29749
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069085
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35661
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05663
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41233
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18141
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96601
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981711
GSE231891_3_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17598
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877157
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830097
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58871
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03144
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93193
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95994
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11618586-41467_2024_55008_MOESM1_ESM.pdf-16-ZNF654_ZNF654	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43369
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28461
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.32457
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24594
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
GSE209680,GSE209683_0_v_1_nfat5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997869
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69467
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.453
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.0929
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38312
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17263
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11311
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27441
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32851
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35238
CAL-101	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051525
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.80339
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12718
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26211
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96072
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5142
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20586
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882059
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053719
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24352
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91623
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58227
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926495
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0104
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.52907
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6183
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29843
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.343011
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59161
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0035
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38892
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0731
EP300	ENCODE Transcription Factor Targets	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00999
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16671
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18933
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.23997
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28809
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5782
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054277
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3036
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35238
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CBX8	ENCODE Transcription Factor Targets	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4758
hsa-miR-3174	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39582
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10032
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.91
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33827
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05272
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06839
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25817
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.428
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00903
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.219
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72874
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07128
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5464
PTEN_01_301	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59002
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLN4924	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.96
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04643
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40473
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53589
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8772
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34765
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0277
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63539
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40416
LS1034	DepMap CRISPR Gene Dependency	1.0	3.0559
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835209
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Extended_Data_Table_2_Significant_regions_of_DNA_copy-number_alterations_by_DNA_methylation_class_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842701
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24788
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7869
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20009
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860119
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_13511_OE_Nfkbiz_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.18024
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06989
TP53	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13647
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91027
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03704
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972272
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5871
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32362
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8211
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865428
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07646
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20919
hsa-miR-1243	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5394
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837154
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35564
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05508
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62302
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36662
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6330_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49158
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WM115	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01997
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23289
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871683
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26581
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-2.86655
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55003
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15721
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10573
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10454
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26808
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	1.45337
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02819
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3218
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10023
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06085
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28041
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912402
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06545
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.841
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07424
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57071
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57652
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81988
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2783
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1764
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699444
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23533
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65478
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.60006
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19001
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05464
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13147
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.45671
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09815
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00228
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.97714
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09917
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0931
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.94906
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14982
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.339
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38694
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74937
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09248
Subsynaptic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885134
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03762
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09726
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6995
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02725
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60116
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8272
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039252
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51813
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.66469
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7973
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13747
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17087
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46547
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8209
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39588
Intermediate filament protein, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1161
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930039
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11709
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	8.51385
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26933
IRX4	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC11994450-44161_2025_628_MOESM3_ESM.xlsx-Supplementary_Table30-Supplementary_Table_30_Top_100_EC2_subcluster-specific_markers_in_carotid_atherosclerotic_plaque_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
CHEMBL2041153	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
CLPP_KO_GSE40207_382_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32684
KP1N	DepMap CRISPR Gene Dependency	1.0	2.47129
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3275
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13275
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
CAKI2	CCLE Cell Line Gene Expression Profiles	1.0	2.40872
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78131
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55904
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.58559
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891901
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882104
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6915
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82712
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11714
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15103
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8333
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15924
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5063
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4468
Diffuse alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Marimastat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59517
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20852
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1991
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3703
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6492
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7076
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8301
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44599
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914468
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37185
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69902
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6837
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12496
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57192
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34575
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852013
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66503
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84817
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17397
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11143
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977726
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.9324
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64105
GSE148066,GSE157787_3_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27281
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02238
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94176
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
HOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_2_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66032
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15015
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874958
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8445
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GW9508	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55411
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17724
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26756
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06528
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.991514
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14548
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865584
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6954
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05294
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1198
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1457
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9168
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1409
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17581
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9799
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2348
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06137
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26434
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44914
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90166
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5032
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96174