association	dataset	threshold value	standardized value
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976237
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4883
Intermediate filament protein, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62768
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24892
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18086
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48479
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17427
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869192
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10579
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	2.06814
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14191
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
Adrenal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64408
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3482
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.598
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7623
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21511
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7463
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40168
GSE209601_2_v_3_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45098
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06679
Monilethrix	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22444
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.998647
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05902
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8571
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67094
H zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80357
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20009
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7942
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2553
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
SC 560	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
PMC12430004-ugae028_Supplemental_File.pdf-9-IKZF3_IKZF3	Rummagene Transcription Factor Associations 2026	1.0	null
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28399
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89392
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21451
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00062
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07279
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28332
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63176
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.64908
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32285
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15924
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29569
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970397
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874837
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30507
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958034
Conjunctival degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824736
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24581
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13294
NFYA	ENCODE Transcription Factor Targets	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337808
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9929
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972272
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A 438079	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.58
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4535
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74625
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9747
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Moh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842701
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00999
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64305
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87428
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46698
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23533
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20586
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94978
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92267
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99812
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pomalidomide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23492
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08569
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00912
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10348
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4444
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97437
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55904
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30018
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31928
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAB33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11228
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.81459
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039414
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34306
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4719
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78593
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08874
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908242
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05464
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01455
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01396
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A23V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840033
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885405
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85145
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47094
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46759
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3103
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1925
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847145
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAPK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0123
B4GALT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12086
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.832664
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.77293
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32123
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17614
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74643
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-geneID_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06077
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1938
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5622
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95111
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855275
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25803
Perturb_16564_KD_Eda_SRP110814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31177
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044634
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05794
RERFLCSQ1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79878
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Patent ductus arteriosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909064
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85895
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855111
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94148
RBBP5	ENCODE Transcription Factor Targets	1.0	null
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81988
PF-04418948	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5375
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39582
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36818
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45107
hsa-miR-1243	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954373
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	1.45337
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
6603-0104	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
Acute Myeloid Leukemia_LAML_TCGA-AB-2855-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00062
GSK4112	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal pseudo-obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
GREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80087
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997803
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7092
KIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91674
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112707
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37117
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28164
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31129
TR-14035	DeepCoverMOA Drug Mechanisms of Action	1.0	0.23
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86481
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.30628
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42538
Perturb_6165_KO_Tet2/Tet3_SRP060364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.35091
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56394
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63539
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23348
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05152
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.66469
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843708
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
GSE148066,GSE157787_8_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0931
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40374
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6048
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16819
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875537
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.236
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.33381
Basal node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
PMC5245798-pgen.1006538.s023.xlsx-Sheet1-HOXA2_HOXA2	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18141
IRX4	MotifMap Predicted Transcription Factor Targets	1.0	null
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2992
NRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15024
YY1	ENCODE Transcription Factor Targets	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63999
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06137
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826665
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043395
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63618
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57192
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05198
FLI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01131
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.585
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77164
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7076
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02341
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.9324
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01525
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21349
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14982
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nonsyndromic congenital nail disorder 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6833
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01697
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8059
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907411
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40242
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1682
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913403
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861709
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.03224
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
ASCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05557
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52164
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132956
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79732
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7801
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21689
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7869
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14571
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80004
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069085
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67638
TRAF3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79478
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2967
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00365
GSK2656157	DeepCoverMOA Drug Mechanisms of Action	1.0	0.41
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05307
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ileus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09394
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52171
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01927
CAKI2	CCLE Cell Line Gene Expression Profiles	1.0	2.40872
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54937
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22438
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
EWP-815	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.32
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14565
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943743
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3373
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47188
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2539
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59807
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47519
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3255
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.841
LU99	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0277
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7498
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838449
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06078
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5871
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0015
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054751
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07911
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2806
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.56962
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4199
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1456
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53629
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40473
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6782
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91915
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864367
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09585
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02262
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CTCF	ENCODE Transcription Factor Targets	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02577
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
DMWD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50404
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29843
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974265
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.91
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16954
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34973
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0962
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13193
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699444
TAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8423
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051525
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57884
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41333
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4758
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FED48h_vs_D2FAST48h_968_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hmc1	HPA Cell Line Gene Expression Profiles	1.0	2.54962
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0096
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05879
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70132
OAW28	CCLE Cell Line Gene Expression Profiles	-1.0	-2.86655
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15091
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47427
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828072
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96123
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834721
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938451
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30921
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.92625
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-XOTO-0226-SM-4B66H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827277
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19408
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06085
VTI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94082
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6204
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22105
FH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09584
OCUBM	DepMap CRISPR Gene Dependency	1.0	14.6073
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30346
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.964467
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.338
KDM1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33292
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77006
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92373
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09726
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2756
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ACVR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8226
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01686
Perturb_16604_KO_Phb_SRP229743	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45143
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9318
COMMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03588
Guanfacine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.943055
GTEx Esophagus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	8.49907
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0136
SOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38532
SNU878	CCLE Cell Line Gene Expression Profiles	1.0	1.75541
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41757
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869275
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86719
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81961
FNDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99893
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1566
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.87447
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B7-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6492
Ruboxistaurin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
Vilazodone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.59
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17916
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1668
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837154
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	ChEA Transcription Factor Targets	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1813
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.4211
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949571
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19596
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.86405
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6763
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07285
GSE158197_2_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36652
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0162
GSE220520_3_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3227
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.61897
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.952623
Keratin, type I	InterPro Predicted Protein Domain Annotations	1.0	null
Genistein	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
ntera2	HPA Cell Line Gene Expression Profiles	1.0	1.02315
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7643
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18064
BHLHE41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14261
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.645
gallbladder	HPA Tissue Gene Expression Profiles	1.0	0.880131
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19163
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9431
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887611
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58871
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34858
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77885
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20852
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLPP_KO_GDS4791_376_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8209
SW626	DepMap CRISPR Gene Dependency	1.0	4.39537
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55687
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2198
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88578
JHH5	CCLE Cell Line Gene Expression Profiles	1.0	1.34767
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1183
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15075
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37185
TSPYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39278
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06207
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDGFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30705
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01584
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899483
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882059
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8594
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11418
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98696
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91236
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22997
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.782
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71141
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4315
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56182
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07843
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41686
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84757
LARGE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92441
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15504
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6837
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35238
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53796
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36099
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01102
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240497
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.63013
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mp14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1161
Intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46776
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858497
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31171
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48821
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7465
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
BCL2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58168
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00008
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4468
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68769
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998775
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2294
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27541
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61188
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05857
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83275
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828855
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864668
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70038
Adenosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.42603
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38892
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920768
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052404
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23268
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17598
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30674
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nonsyndromic congenital nail disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
Cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
rectum	HPA Tissue Protein Expression Profiles	1.0	1.0929
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27907
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58542
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34691
Subsynaptic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09561
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5748
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	2.71406
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASPC1	DepMap CRISPR Gene Dependency	1.0	3.68137
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3818
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.3587
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28333
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCPRF5	CCLE Cell Line Gene Expression Profiles	1.0	1.6301
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82428
PMC12978397-wjon-17-02-247-s002.xlsx-S2-Suppl_2_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903281
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35302
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966363
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-2.8215
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5731
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NF-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9701
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35859
Sarcoma_SARC_TCGA-DX-A8BV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9849
HCC366	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64687
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953896
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.663
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27085
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941845
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15779
DMS114	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47372
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848092
hsa-miR-4455	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55642
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0461
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79458
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16506
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54241
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76153
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06174
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57781
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7559
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05943
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839237
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9325
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924689
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01756
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42284
GSE60691_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCA1	DepMap CRISPR Gene Dependency	1.0	2.29797
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51146
Burn wound healing	WikiPathways Pathways 2024	1.0	null
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54774
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936385
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70848
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09505
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16564
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.85458
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
POU5F1	ChEA Transcription Factor Targets	1.0	null
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95364
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08145
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37405
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825405
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07419
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927275
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46906
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00597
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4257
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34828
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8364
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05652
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3157
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996749
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10454
AP3M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45016
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995047
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55837
GSE231891_3_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03252
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07615
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RO495	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.88
H1-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99308
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01316
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-495	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83727
AQP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81384
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00069
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34765
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22071
GTEX-XYKS-1626-SM-4BRUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905185
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51813
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.02997
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41191
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25464
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830005
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26536
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34687
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58615
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054297
MGME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18126
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11143
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00304
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.913609
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985023
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66032
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949571
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977744
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98608
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21312
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31171
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78821
RBPJ	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08806
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62187
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5116
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02221
Sarcoma_SARC_TCGA-DX-AB2F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.947949
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61641
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30458
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8393
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.43728
Huntington's Disease_Brain_GSE3621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.95825
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	3.63212
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830097
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20174
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86141
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55428
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852895
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02729
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.89156
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08493
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89358
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01051
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.49608
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32419
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96174
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08287
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37334
PX-12	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.61
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9695
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98365
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70665
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835946
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
PPARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13152
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59565
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07478
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_01_324	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60268
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67095
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2912
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
Foramen magnum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)_30Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.13345
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00202
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01166
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963111
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.996837
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.74571
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62685
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58036
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40416
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86451
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82609
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42444
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849051
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37625
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3026
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63517
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830938
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59601
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39328
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05092
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07627
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15876
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
terminal hypothalamus (rostral hypothalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13217
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11129
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61482
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55097
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4261
GSE171837_0_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15662
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31811
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0075
ZNF610	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44176
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07191
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.30104
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39826
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44545
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0104
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31235
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4B-Up_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	8.51385
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039007
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94176
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5477
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.08627
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41651
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06839
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14548
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937051
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93347
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08823
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
White sponge nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45348
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887685
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18198
Sarcoma_SARC_TCGA-3B-A9HL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	2.42162
hsa-miR-4469	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MFSD14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55184
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12933
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20197
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03472
Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35637
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15532
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88141
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KYAE1	DepMap CRISPR Gene Dependency	1.0	10.8333
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88694
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13535
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.128
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93347
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38081
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1314
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06672
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0887
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30907
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.88818
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.156
PMC6932815-ppat.1007634.s011.xlsx-ST1_DGE_ELF1_lfc2_fdr05_interse-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13511_OE_Nfkbiz_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.18024
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20754
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4893
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58923
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926495
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857649
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53364
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39091
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861747
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32629
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U2OS	DepMap CRISPR Gene Dependency	1.0	2.47024
CUX1	ENCODE Transcription Factor Targets	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3719
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9041
NIBR189	DeepCoverMOA Drug Mechanisms of Action	1.0	0.36
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86142
Trihydroxyisoflavone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20979
Metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.25992
ID1_01_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58664
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64105
brain	HPA Tissue Gene Expression Profiles	1.0	1.63755
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
Perturb_6330_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49158
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979051
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
CDK20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78344
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Cognitive decline rate in late mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
C1orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07171
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12496
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31467
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17724
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848186
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86597
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915376
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96601
LIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64045
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62852
AM 630	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98537
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39139
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU16	DepMap CRISPR Gene Dependency	1.0	2.52272
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09946
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864625
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936755
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26089
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6307
Cetrorelix	DeepCoverMOA Drug Mechanisms of Action	1.0	0.47
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59831
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8445
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9961
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17581
ZNF384	ENCODE Transcription Factor Targets	1.0	null
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44248
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16875
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68214
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57204
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36784
abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568823
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965213
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86245
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30304
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35238
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893565
hsa-miR-4502	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siYAP_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11718
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25892
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948799
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26503
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0061
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89985
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0799
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07183
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78608
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53589
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6958
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32362
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OCILY18	DepMap CRISPR Gene Dependency	1.0	2.06004
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51944
medial geniculate complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19738
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
CNOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88225
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01922
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D4REFED48h_750_AR--Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56269
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1267
ARID3A_02_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.10434
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988363
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82294
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE148066,GSE157787_5_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12984
mpkCCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.60006
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34034
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23289
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85535
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12993
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33086
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26638
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27525
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95885
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0438
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86328
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11086
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9168
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949012
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6737
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3053
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901448
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39679
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980038
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910342
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05508
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97738
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52318
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21202
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3875
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6999
WM115	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01997
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12718
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01864
MONOMAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71812
JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.74449
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51029
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11311
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26406
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33396
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11375
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824392
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44742
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04643
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7864-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_13513_OE_Card11_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.30614
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	2.77729
Eukaryotic translation elongation factor 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51J-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
Prostate adenocarcinoma_PRAD_TCGA-G9-6385-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01641
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10875
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36969
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65992
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.08394
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75775
SCC9	DepMap CRISPR Gene Dependency	1.0	4.51864
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26328
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9374
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7793
hsa-miR-3650	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839984
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899345
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03671
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07424
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29972
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04558
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50579
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33827
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3392
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959405
intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32868
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948791
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04308
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924329
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55411
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88274
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12716
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66836
JQ-1	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.3
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.49562
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58665
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Guanethidine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874404
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13275
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
TRIM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10868
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15004
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
TDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00016
White Blood Cell Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885134
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11315
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68702
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850898
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62648
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06094
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29898
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00651
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58249
Yohimbine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11714
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927448
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912941
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91927
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02614
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61477
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4629
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04894
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9565
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95762
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5288
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18018
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948639
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00825
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2348
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94972
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44549
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24468
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976062
Perturb_16827_KO_MLL4_SRP058264	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.09295
ZFAND2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36448
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0568
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44599
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873066
CHEMBL2041153	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78145
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11435
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1903
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39588
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82676
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1345
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.727711
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08518
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15227
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04694
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64784
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	0.910874
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38694
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17122
Intermediate filament protein	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28809
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32141
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07128
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.365
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86249
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.509
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14544
protein complex	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28159
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ELF1-20517297-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52171
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53438
SMC3	ENCODE Transcription Factor Targets	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929879
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45506
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46547
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25817
KIJK	DepMap CRISPR Gene Dependency	1.0	3.96897
CAL-101	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57458
CFPAC1	CCLE Cell Line Gene CNV Profiles	1.0	1.39449
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51314
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69994
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56144
AS-605240	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.219
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08004
GSE195559_0_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23234
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34455
HS172T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5805
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23217
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46126
OAW-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.835209
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4713
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918433
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.49699
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
SKLU-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29347
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0711
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.57151
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
TBP	ENCODE Transcription Factor Targets	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.958082
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.94906
IRX1_01_227	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.45814
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80156
Chorionic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.82717
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977079
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.82712
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70411
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860119
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24261
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07126
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40017
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02238
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.83548
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07676
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81466
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.149
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34977
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72874
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054277
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925818
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0247
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68999
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.0783
ATXN7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91451
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84817
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64534
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28692
Type I terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37821
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30244
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01221
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894154
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54189
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1213_KO_Zfp580/Sp3_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.60378
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0461
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.39673
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6985
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978736
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43176
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21427
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0027
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
DKK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60719
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13747
SENP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65743
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10457
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3703
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
XCT 790	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.38
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	0.839066
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964565
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874212
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38189
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1236
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56883
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07837
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12521
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2208
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.28326
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15702
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51569
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20341
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46788
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66723
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1991
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12279
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58665
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A4FUK	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75482
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04075
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04026
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25878
MYCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25429
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2449
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06094
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887695
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5032
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4861
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4234
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.32659
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.13936
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.923533
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18645
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55003
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3737
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6183
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.46281
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981711
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62302
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86946
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66536
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22436
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926234
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.23775
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57316
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01896
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911299
metencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.66914
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96372
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60523
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92484
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30759
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924325
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59252
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23729
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0908
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9234
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
TRIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52194
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15826
TMN 355	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.91
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1899
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4832
Sarcoma_SARC_TCGA-IF-A3RQ-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6944_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26721
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3232
ABL1_mutant_24_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.38505
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24723
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86409
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06215
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847321
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06337
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93662
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26581
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86292
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39808
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26958
ROS50	DepMap CRISPR Gene Dependency	1.0	2.25948
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0104
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45165
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05549
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74923
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.453
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RBM25_02_166	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	1.45381
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20056
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5021
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1457
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84647
SPACA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72195
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2783
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4995
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2081
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.981124
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6568
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3HAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
Pterygium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01282
CLPP_KO_GDS4791_541_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877157
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01987
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34451
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85121
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26822
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4943
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68603
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68166
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09815
Perturb_14724_KO_Dicer_SRP082704	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.4416
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99626
HOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
intermediate filament	GO Cellular Component Annotations 2015	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01492
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19588
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.783972
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	4.65835
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GYPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32851
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900301
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76296
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07191
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71671
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5237
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24965
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.99868
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.8887
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4774
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985506
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912402
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35425
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37208
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84273
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26933
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5284
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.972594
ZNF638	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41197
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864979
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2666
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57652
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08975
liver_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.09801
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8004
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0836
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42177
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39696
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-Genes_with_VDR_elements_only_control_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80036
CCZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75498
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4762-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11885
Cerebral arteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13089
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP5MJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.289
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49198
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923569
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34574
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27796
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78131
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09912
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11618
PCI-34051	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.39
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854358
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42008
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10243
LS1034	DepMap CRISPR Gene Dependency	1.0	3.0559
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7221
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97268
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24025
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10083
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00228
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92946
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4665-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51527
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.4221
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.57681
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74382
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
CAPAN2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53492
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09247
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15103
CS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66443
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02187
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79814
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995995
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38727
PLEKHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52133
GLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90483
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11799
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.57823
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43369
PHTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74737
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10056
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9878
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7122
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0451
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NLGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1096
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7396
TCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81403
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13147
GW9508	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29374
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59517
PMC11618586-41467_2024_55008_MOESM1_ESM.pdf-16-ZNF654_ZNF654	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13669
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92687
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16862
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06458
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930039
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7006
GSK2334470	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.64
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3796
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72011
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0455
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80614
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNCRIP_02_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6602
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02725
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48764
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
QRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34554
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7485
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12027
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
WDR5-24793694-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39581
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54633
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9625
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91514
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885922
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8772
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11648
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18933
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836285
Asthma or allergic disease (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.339
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14544
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975832
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5072
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
RS5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91623
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4381
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.991514
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5498
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03331
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874045
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40988
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9982
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62591
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1281
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39011
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36662
SLC33A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57832
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4767
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A655-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24644
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503141
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19727
cerebellum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40629
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08047
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.46253
CSNK1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46321
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51222
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	3.65944
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837583
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1901
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17713
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5464
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.32457
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28217
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06528
Perturb_17721_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77013
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028752
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24594
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79452
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11833
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5063
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30467
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50161
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47547
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36184
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DCUN1D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.54025
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8394
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.45671
ELF1	ChEA Transcription Factor Targets	1.0	null
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11833
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882104
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8272
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02055
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20088
HCC1937	CCLE Cell Line Gene Expression Profiles	1.0	1.40272
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0035
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45892
H3K4me1_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KE37	DepMap CRISPR Gene Dependency	1.0	2.48609
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26102
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2508
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HT1376	CCLE Cell Line Gene Expression Profiles	1.0	1.4992
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4074
GSE220520_3_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8791
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0219
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999661
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SI-01A-31R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1198
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06291
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2249
JTE 013	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Testis 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.27573
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TB-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978194
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stipe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
WDR74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51042
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24826
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04623
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26808
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16128
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2335
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5192
Anagrelide	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6377
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1474
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Outer kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78238
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10573
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67755
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
Root cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25832
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13647
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19809
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226926
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94477
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
GSE209680,GSE209683_0_v_1_nfat5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941378
HCC2998	DepMap CRISPR Gene Dependency	1.0	10.0118
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10023
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21937
Rif1_KD_GDS4943_243_mouse_F1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4333
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904862
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98583
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19026
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21368
Gingival overgrowth	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7724
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28812
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901604
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.862445
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86714
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40299
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12593
PMC12211054-spectrum.00100-25-s0002.pdf-13-ZNF331_ZNF331	Rummagene Transcription Factor Associations 2026	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09114
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A766-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.44876
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39633
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01023
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891901
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907611
organelle part	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05663
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS-Cov_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.90155
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.0362
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87305
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94424
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26519
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26756
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45965
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77517
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890364
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54492
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0731
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29228
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937044
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24468
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35807
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64428
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93746
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910441
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86011
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15324
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09917
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841601
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6915
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5142
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0485
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73B-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19726
GTEX-W5X1-2626-SM-4LMI8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1697
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20919
Adrenal gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
OGG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30406
Blonanserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.61
UQCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.401
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02595
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.915719
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13572
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93496
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895008
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2611
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16394
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3275
ETS1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86631
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.41233
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904184
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10511
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25656
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hindbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848256
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0535
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15719
cd8 cells	HPM Cell Type and Tissue Protein Expression Profiles	1.0	0.957324
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31414
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5538
GSE223378_1_v_0_tead3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971546
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05827
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52202
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11279
PMC11994450-44161_2025_628_MOESM3_ESM.xlsx-Supplementary_Table30-Supplementary_Table_30_Top_100_EC2_subcluster-specific_markers_in_carotid_atherosclerotic_plaque_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93193
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.825929
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4728
Olopatadine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33211
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35183
hek293	HPA Cell Line Gene Expression Profiles	1.0	1.23054
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0237
GLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81605
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75222
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80124
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90776
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SLC39A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64556
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.97714
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31145
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922573
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28828
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69467
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37899
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2539
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44043
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0647
ACSL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2003
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58227
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8301
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20592
Pith	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8272
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54986
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8333
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Terazosin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.41
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08653
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14386
GSE162623_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.964723
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
SF3A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86295
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1409
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74682
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057085
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38642
KLF1	ChEA Transcription Factor Targets	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5711
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6446
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29749
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16351
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77244
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06006
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79313
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2253
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05928
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051525
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929303
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
USP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96072
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29614
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28461
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9344
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GADD45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1655
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831125
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41262
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.73005
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.924429
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.23997
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03144
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15533
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.76247
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.428
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65449
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.82684
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865584
RBM15_02_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8137
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17056
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61779
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928861
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944822
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Allergic disease (asthma, hay fever or eczema)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
TRAPPC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37116
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32331
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884425
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32851
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TWIST1_01_253	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59509
BOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95923
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994272
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72776
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0276
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.92186
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20912
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29836
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13543
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14846
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98537
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96289
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29957
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7383
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25179
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00584
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19545
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10426
RNF2	ENCODE Transcription Factor Targets	1.0	null
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A2780	CCLE Cell Line Gene Expression Profiles	1.0	1.55386
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17793
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74937
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92895
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869479
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35564
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52941
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8214
HAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3218
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17263
TXNDC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42981
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92054
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.37398
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66674
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sartorius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955211
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04769
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18449
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19484
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57071
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02941
CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2414
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-13.9843
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99742
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68563
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836067
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8211
SNRPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23911
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.859802
JVM3	DepMap CRISPR Gene Dependency	1.0	4.42618
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10462
3-M syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CLINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78567
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78332
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57801
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14251
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17087
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Intestinal volvulus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07646
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16163
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14916_KO_Cd2bp2_SRP034660	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.86358
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49073
SLC8B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71178
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3704
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0835
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.0929
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81402
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4466
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90497
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02819
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.876
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.44875
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2543
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51474
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03842
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26371
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852013
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07285
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865428
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14846
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42676
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84572
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69902
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898034
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1542
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27615
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.916607
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26581
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7164
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13284
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8114
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8567
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9452
CLPP_KO_GSE40207_382_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7913
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59565
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17778
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4037
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49182
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24447
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91027
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6956
PMC12913833-12672_2026_4481_MOESM3_ESM.xlsx-Table_S1-Table_S1_Two-sample_MR_analysis_of_blood_eQTLs_associated_with_LUAD_P_0_05_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Extended_Data_Table_2_Significant_regions_of_DNA_copy-number_alterations_by_DNA_methylation_class_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.10557
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.905292
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894026
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	1.64116
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2329
intermediate stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05294
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87302
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE158834_12_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880718
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.52907
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90477
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04249
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44922
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
NR0B1	ChEA Transcription Factor Targets	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12727
KP1N	DepMap CRISPR Gene Dependency	1.0	2.47129
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1106
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.934544
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07292
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.926
JHH4	CCLE Cell Line Gene Expression Profiles	1.0	1.70684
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871683
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6252_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.5752
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24788
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39708
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diffuse alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC19A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4521
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13492
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
ARHGEF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08895
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7605
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977726
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35661
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2248
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Grey cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23171
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
GSE57871_8_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF7IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03589
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837693
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09885
FAM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84378
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
CLPP_KO_GSE40207_399_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02187
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10032
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12079
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9799
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42658
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79619
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
pretectal nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835459
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65513
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912283
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.62377
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE112761,GSE112767_2_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911791
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01411
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0494
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0247
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87114
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82795
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17768
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988768
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04665
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
GMFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33041
GSE195559_2_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3701
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72602
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.7224
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01896
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63417
hsa-miR-3174	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2105
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40434
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1251
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04459
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24112
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91152
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	2.73869
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.343011
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850898
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862701
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09248
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.998
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94459
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	241.352
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27441
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921483
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5782
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7134
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14429
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990811
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.80339
C32	DepMap CRISPR Gene Dependency	1.0	2.91361
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3698
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06925
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4813
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47878
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12945
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03704
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5373
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3036
EFM192A	CCLE Cell Line Gene Expression Profiles	1.0	1.95767
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57864
IOSE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09412
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3942
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36054
PAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96702
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06545
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826378
OSRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.81343
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06545
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976165
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08181
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.40505
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16953
Papaverine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
GSE145639_1_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22893
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01831
SKN3	DepMap CRISPR Gene Dependency	1.0	2.68868
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lhx8	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5215
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08999
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86776
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837545
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Varespladib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35639
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868558
GSE148066,GSE157787_3_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12103
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.26725
Trunk kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053196
NCIH28	DepMap CRISPR Gene Dependency	1.0	2.5822
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43302
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2125
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49458
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8176
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4092
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1775
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26368
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTEN_01_301	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59002
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984469
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08439
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912071
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3052
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997869
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24352
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3668	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08806
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16283
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11721
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Alveolar mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
MLN4924	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.96
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3712200-584604.f1.pdf-44-SPDEF_SPDEF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4525	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
4-Benzylpyridine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17638
TOV21G	CCLE Cell Line Gene Expression Profiles	1.0	1.65689
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00771
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6995
GATA3-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939791
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76602
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12528
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039359
u2197	HPA Cell Line Gene Expression Profiles	1.0	1.15275
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8682
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49322
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4572
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85177
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.37345
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66602
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45408
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842002
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06278
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976124
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82237
GTEX-XAJ8-0926-SM-47JXZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914686
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96724
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18086
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58711
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7853
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17227
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26881
CHD1	ENCODE Transcription Factor Targets	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3158
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05027
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65175
Perturb_7030_KO_Erg|Fli1_SRP402910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.030588
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04601
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_0_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.246
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28296
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95521
JUND_02_16	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.11548
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83117
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.36739
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3912
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851424
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861531
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15015
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05165
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27988
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03762
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.377
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5973
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37624
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02891
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
skin	GTEx Tissue Gene Expression Profiles	1.0	1.17725
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.0079
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06989
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57024
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26211
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64687
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2688
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69873
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.861519
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28041
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053719
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843828
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23061
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07393
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21245
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60462
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42702
GTEX-U8XE-2526-SM-4E3IT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911637
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59161
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.863187
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65268
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1764
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897604
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.65708
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.344
Tick infestation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16643
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
liver_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.839358
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5765
bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.078553
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839696
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_2_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1351
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40062
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1396
Diverticulitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.0929
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72182
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parasitic ectoparasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34575
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86749
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08927
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7939
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11209
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922705
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907594
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46727
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41943
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97373
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07279
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.44081
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11484
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8013
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01196
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083082
T84	DepMap CRISPR Gene Dependency	1.0	2.17922
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84124
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54136
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27281
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5061
GTEX-XQ3S-1226-SM-4BOPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852259
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57331
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11457
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057211
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17744
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914468
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41364
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12219
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978733
stomach	HPA Tissue Protein Expression Profiles	1.0	1.0929
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97219
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
SCGB3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72848
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15721
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17093
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980096
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5394
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4126
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59293
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892473
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60122
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2956
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11975
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21245
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36398
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46522
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49906
Pinguecula	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.26176
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95994
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46691
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1098
Congenital epulis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.93762
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65478
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38648
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51586
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44162
hsa-miR-340	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Timapiprant	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84634
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02779
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62929
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9CZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66503
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72686
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35333
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858664
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79662
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913126
Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23801
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.939755
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
SLC18B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78651
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90166
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7895
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848533
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57386
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922531
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.8
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14219
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856116
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCIN87	DepMap CRISPR Gene Dependency	1.0	5.01248
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64569
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Type III polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.877
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21161
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6954
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.85185
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964967
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0675
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20934
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39665
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04171
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CALU-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231799_3_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6358_KO_NumbL_SRP307901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.83489
NDUFA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91832
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5361
Volasertib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.22
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850792
HNRNPH1_02_08	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.12928
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.333
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7973
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20852
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19001
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE212762_1_v_2_smarcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53277
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20736
CANX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12012
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849165
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5627
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72003
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60116
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845026
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31605
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7062_KO_Mbnl1_SRP014709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.0088
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.17397
Alfuzosin	DeepCoverMOA Drug Mechanisms of Action	1.0	0.38
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22583
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58459
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.58559
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48693
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.1676
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11987
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02376
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16035
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30229
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2791
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246716_0_v_1_trappc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25125
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.687
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08221
hsa-miR-3919	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35904
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.85699
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.61397
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00903
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36897
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843282
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00202
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35622
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9892
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55251
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.09314
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	2.20946
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02605
UBTF_02_198	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.8365
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16613
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02011
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.51201
TMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21365
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04132
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26434
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03869
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64496
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05391
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992931
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847142
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71812
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38375
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.290565
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476979
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78921
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984469
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03293
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7293
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0059
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83231
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83197
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32001
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
Marimastat	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885239
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.954702
TE6	CCLE Cell Line Gene CNV Profiles	1.0	2.66863
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93017
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05016
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14771
DLGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43227
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8902
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994781
Lung squamous cell carcinoma_LUSC_TCGA-66-2763-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05272
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3598
PMC3639976-pone.0063011.s017.xls-DataFrame-Dataset_S3_Microarray_analysis_of_HeLa_cells_treated_with_si-PPARD_in_the_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1119
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06137
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58232
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11709
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823917
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994681
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06528
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13445
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.945436
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17234
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48156
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06943
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.415
PMC10794847-mmc2.xlsx-PBRM1_KD_down-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37145
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26617
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03966
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82983
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039252
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831005
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879212
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915436
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84806
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8585
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93274
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52626
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6789-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44914
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909422
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982132
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43094
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1523
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46705
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16671
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34517
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3719
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D1FED24h_vs_D1FAST24h_259_AR-DE-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874958
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05201
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33356
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38457
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95977
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00357
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2548
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32684
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85466
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51798
NB1	DepMap CRISPR Gene Dependency	1.0	2.31131
SNU46	DepMap CRISPR Gene Dependency	1.0	2.73123
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67982
KYM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38312
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
SYNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86415
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1990	DepMap CRISPR Gene Dependency	1.0	5.3262
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45239
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860346
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80739
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24093
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37568
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-1275	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26722
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40896
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null