association	dataset	threshold value	standardized value
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04417
binding	GO Molecular Function Annotations 2015	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Ampicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0022
CRCGN016_MCF10A.TP53.M_24H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46109
triamcinolone-1395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Secretory granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
BRD-K82175530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6811
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3192	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH841	CCLE Cell Line Gene Expression Profiles	1.0	1.60388
vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K21201014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25066
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.952
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59385
etodolac-1407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869742
BRD-K32259584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24757
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07249
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87082948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2115
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7079
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496483
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70355
BRD-K90827020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24194
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC9377669-tx1c00392_si_002.xlsx-Valproic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CHEK1_knockdown_142_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.39349
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9702
OS252	DepMap CRISPR Gene Dependency	1.0	2.25947
NCI-H1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RH28	DepMap CRISPR Gene Dependency	1.0	6.06136
BRD-K61623863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92667
BRD-K43473008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31261
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.297
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38875
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.785071
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15998
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0401
trans-Golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75674
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70952
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986541
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MELHO	DepMap CRISPR Gene Dependency	1.0	4.58943
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17405
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27091
KRAS.600_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32334
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3217
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930188
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.297089
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13973870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07661
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
KRAS.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961977
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47478
PNU-0230031-4288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06668
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.92216
Hair follicle bulge stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52836
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4487
BRD-A90450579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71655
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7427
PMC9582139-Table_1.xlsx-ERBB2-KD_fusion_patients-gene2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.87585
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055468
isocorydine-1787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28271
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40159
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.767
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.00035
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62533881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31793
fulvestrant-5202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.65131
Inflammatory Bowel Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04437
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69328
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.01
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	0.530188
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06503
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9993
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991698
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37412
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27058
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29994
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04147413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47156
Spiral organ cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
HS939T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49438
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04438
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.419
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.651221
BRD-K31479652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46922
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87981
KKU100	DepMap CRISPR Gene Dependency	1.0	2.59518
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29988
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57381
NCIH82	DepMap CRISPR Gene Dependency	1.0	14.2133
BRD-K87383650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04801
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00637
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881379
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214714
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01685
BRD-K97359891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43537
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170054
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859828
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelium development	GO Biological Process Annotations 2025	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53402
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.06805
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.062124
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36119
JHH4	CCLE Cell Line Gene CNV Profiles	1.0	1.39856
cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483273
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
cytoskeletal part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE33	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053323
hsa-miR-4436b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
EWSR1_KD_GDS4962_465_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10603
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9542
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056195
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2563
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.927837
H-89-6873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.320826
alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.358183
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88287
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-A20477000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03592
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.61367
PMC9377669-tx1c00392_si_002.xlsx-Sucralose-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56026
SW1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19046
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14493
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081525
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02859
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25148
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17053
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03246
Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8577
LOVO	CCLE Cell Line Gene Expression Profiles	1.0	3.40802
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cefepime-5761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.3
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09582
flufenamic acid-1420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VA-ES-BJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
levallorphan-tartrate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28031
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36935
vinpocetine-1557	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RL95-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.73789
BRD-A77292814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63773
BRD-K96945247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07685
PMC9377669-tx1c00392_si_002.xlsx-MethylMerc-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949087
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59157
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844545
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0433
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.767
CEBPD	ENCODE Transcription Factor Targets	1.0	null
scalp	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14136
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24766
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03369
hsa-miR-4520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29048
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K15708264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21375
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.04209
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18896
BRD-K61438422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15411
OACP4C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173057
PBX1	ChEA Transcription Factor Targets	1.0	null
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09549
BRD-K79861274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03779
collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483273
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.63343
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37608
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62361
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3217
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324823
NCI 460	BioGPS Cell Line Gene Expression Profiles	1.0	1.19273
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08588
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A14331394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79441
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB17	GDSC Cell Line Gene Expression Profiles	1.0	1.63852
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977147
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30571
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81148
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39593
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28376
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930342
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13994
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06677
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.44287
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.346
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944755
FOXP1_01_88	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59441
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073221
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825522
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.874016
Prostate adenocarcinoma_PRAD_TCGA-J4-A83L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8903
BRD-K85441584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20417
BRD-K92440102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48542
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7872
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0449
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.88358
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879988
skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173057
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37259
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860259
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11282
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79523827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07379
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91467861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35005
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054116
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13843
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38851
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-estradiol-122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
Hair follicle neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86086888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76024
BRD-K29028138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54968
erythromycin-6729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoskeletal part	GO Cellular Component Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9559
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6313
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20674
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16094
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35191
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3031
pyridoxine-1759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-151-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09102
AN3-CA	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66283
BRD-K28059618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2263
BRD-K40964045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3016
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23456
PMC9377669-tx1c00392_si_002.xlsx-Ascorbic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7069
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76603
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39709
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_5910_KD_GATAD2A_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.8339
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3145
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54618
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.405
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312827
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pilomatrixoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
niflumic acid-5490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prazosin-6315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Male breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895729
endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.962627
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45729
BRD-K12984952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05518
BRD-K92134254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11448
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.05
AM38	DepMap CRISPR Gene Dependency	1.0	2.08283
hsa-miR-4463	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5021
hsa-miR-510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K59747214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17467
BRD-K59182232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13562
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.967
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.49992
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04815
cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41371
Endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.27
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03944
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04304
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
vinburnine-1788	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77096
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18665
nodular basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.39258
HEC59	DepMap CRISPR Gene Dependency	1.0	3.02046
Apoptosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01358985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3452
BRD-K79184750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.218
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
phenazopyridine-5758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029819
BRD-K02614439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28192
BRD-K79684522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25606
Perturb_3853_KO_NOS2_SRP325532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.9107
golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.23088
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4578
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.07185
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13739
BRD-K98170574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16099
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.63452
lidocaine-1999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.43726
TCF3_01_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59524
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00513
AP-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.208
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6954
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94841
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17483
SMC3	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.58865
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8719
Intermediate filament protein, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65011
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14415
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59256
BRD-K81644801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65334
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3192
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2999
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69913
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217554
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01725
hsa-miR-1324	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02045
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30589
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-HW-7486-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12664
BRD-K90358614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64243
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064256
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00793
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2693
epithelial stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.667622
BRD-K97638135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24182
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03479638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28064
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23945
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61654
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925025
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06535
BRD-A98795688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4835
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68279
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3998
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90901488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33067
intermediate filament	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0042
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95337
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K12230293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72304
JUND	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948304
Budd-Chiari syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31751
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11846531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20232
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26127722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0289
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	1.2
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K9me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49467822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56553
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238837
BRD-K62965224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40213
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2806
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.27354
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.714189
BRD-K98109987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30488
BRD-K15273135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4728
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.691202
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.88435
BRD-K66479240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59261
ZR-75-30	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46634
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.882367
BRD-K03188480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41012
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74337
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.3292
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07162
naloxone-1924	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN011_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09495
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10438
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15639
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.069182
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.66259
Formation of the cornified envelope	Reactome Pathways 2024	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90604
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34362
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47524
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18928
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7334
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23505
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K08458391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12181
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12969
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.30626
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.15665
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.395
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44528
astrocytes	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.990756
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882417
hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.681064
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03548
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2784
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281453
BRD-K60662039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66685
BRD-K13999467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05829
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14907323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35784
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58748
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30464
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18888
Perturb_7286_KD_HNRNPG_SRP064870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57715
MDAMB415	CCLE Cell Line Gene Expression Profiles	1.0	1.3536
BRD-K88418404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85714
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836327
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94823
HS578T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58816
supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
SKW6.4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
L1236	DepMap CRISPR Gene Dependency	1.0	2.03575
coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.38461
BRD-K36736230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12899
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21601
BRD-K87268607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05461
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0379
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04461
EP300	ENCODE Transcription Factor Targets	1.0	null
BRD-K41779994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03821
BRD-K87951090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54335
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.670471
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6237
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89479
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.261
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68523
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985114
H3K9me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hair follicle dermal papilla cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
riluzole-2295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054732
hsa-miR-4303	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49343
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42281
HOTHC	DepMap CRISPR Gene Dependency	1.0	2.29672
MDAMB157	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99793
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	2.13767
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42879623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19999
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49057
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46483
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082465
L-428	GDSC Cell Line Gene Expression Profiles	1.0	1.49122
Perturb_5903_KD_DDX5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.3979
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0945
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.566338
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68862
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45141
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968134
TCF4	ChEA Transcription Factor Targets	1.0	null
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39846
epithelial cell differentiation	GO Biological Process Annotations 2025	1.0	null
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91374
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13994
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048351
nordihydroguaiaretic acid-524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
collagen and cuticulin-based cuticle extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483273
annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483273
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857353
bucladesine-591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.041405
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1468
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21163
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274835
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
alcuronium chloride-7345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2292
transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.59546
clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.54009
clathrin coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16184
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52038
MAPK1_knockdown_145_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.27966
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Marrow cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
Keratinization	Reactome Pathways 2024	1.0	null
hsa-miR-3616-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17426
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10555
BRD-K55286508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64255
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K94427708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44046
proteinaceous extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.130961
exanthem	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25983
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
KNS60	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32528
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.453
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998547
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468048
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.558285
hsa-miR-4768-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123145
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25776
H3K9me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27473
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18413
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15819
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09761
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1887
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56219
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18114
BRD-A05956997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2011
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0384
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.5023
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09779
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.65472
Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vero cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.530188
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.983405
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051286
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861546
cotinine-2011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5727
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.91203
intermediate filament	GO Cellular Component Annotations 2015	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.02757
hsa-miR-642a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Perturb_8221_KD_ACO1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.38165
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054898
loxapine-2016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
haloperidol-2039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054971
Wilson disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80623
WM88	CCLE Cell Line Gene Expression Profiles	1.0	1.55009
clathrin coat of trans-golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.65513
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54075
Clathrin coat of trans-Golgi network vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26314
Vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
CL11	CCLE Cell Line Gene Expression Profiles	1.0	2.2908
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055106
JY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948304
BRD-K80198069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.009
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68906
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.953447
Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cornified envelope formation	KEGG Pathways 2026	1.0	null
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06461
CRCGN017_MCF10A.WT.HP_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08995
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22701
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86858
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4279
hsa-miR-299-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
membrane coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.11582
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44933
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877144
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02045
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04715
vaccinia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.837656
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055332
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.384
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
CRCGN014_HEPG2_3H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51431
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.968884
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DMS-114	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.384451
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39783
MALME3M	DepMap CRISPR Gene Dependency	1.0	4.12053
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.24071
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052619
BRD-K75038426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26068
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4106
basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.393001
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A50701104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22588
BRD-K45984211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43915
GSE145682_1_v_0_nbdy_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2016
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.98539
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054565
BRD-K95068765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01663
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15213
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6377
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6617
BRD-K73463737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24363
cell part	GO Cellular Component Annotations 2015	1.0	null
IOSE80	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.851913
YWHAG	Hub Proteins Protein-Protein Interactions	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950543
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.462798
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.326453
BRD-K67042874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00266
hsa-miR-4509	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.4904
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.10343
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240276
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6281
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02247
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79756
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.228
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.2831
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14798
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830256
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.446465
edrophonium chloride-2019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03724
BRD-K92312193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34117
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9358
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067764
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67421
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9875
basal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.531879
protein binding	GO Molecular Function Annotations 2015	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2412
minoxidil-1996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.6721
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K86923998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66251
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.94355
esophagus	HPA Tissue Protein Expression Profiles	1.0	0.785071
BRD-K42361742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22397
COLO-824	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056859
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	1.37659
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5443-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	2.00874
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77833
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0116
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.88265
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548m	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H2722	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78814
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24945
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64706
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042256
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32379
hsa-miR-130a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86011
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0311
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29697
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.814
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02074
mebhydrolin-4795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.554015
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A48D-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.005
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K01377768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77091
Staphylococcus aureus infection	KEGG Pathways 2026	1.0	null
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74147
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73671
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0909
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059564
BRD-K67406305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04832
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.46466
BRD-K00081911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10466
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78914
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878329
BRD-K65597286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00067
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1535
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73672
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-4635	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K34534297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42594
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07041
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66037
CRCGN015_MCF10A.WT.HP_24H:C14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04802
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26979
BRD-K01639528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08423
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971155
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05090634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83682
BRD-K07313741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74027
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4537
BRD-K33257311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23174
U178	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92573
BRD-K94516254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29553
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19487
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.082297
intermediate filament organization	GO Biological Process Annotations 2025	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23111
BRD-K25423830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52337
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112135
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84178479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47567
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
RNA nuclear export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94912
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.50094
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K12741517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08925
SLR26	CCLE Cell Line Gene Expression Profiles	-1.0	-2.70589
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0491
dosulepin-2864	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUND_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1106
K562	BioGPS Cell Line Gene Expression Profiles	1.0	1.0938
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
BRD-A75607876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74127
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
DEL	CCLE Cell Line Gene Expression Profiles	1.0	1.48558
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54423
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00196
Graft vs Host Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
BRD-K81099637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06848
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48219
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.23714
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70207
BRD-K37120019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4421
BRD-A41208012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0681
BRD-K36575696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07348
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33325
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-CALL-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65759
T47D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.864312
fendiline-1573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CL14	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
EZH2	ENCODE Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_24H:I15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25481
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.36837
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.473
BRD-K86805916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24077
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06681
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64634
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.03103
organelle	GO Cellular Component Annotations 2015	1.0	null
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59244
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77488
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243605
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
Intermediate filament protein	InterPro Predicted Protein Domain Annotations	1.0	null
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4428
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6826
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43182
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-IK-7675-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35725
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1469
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941143
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18876
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-451b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
chorioallantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380627
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.984372
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55413
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2879
BRD-K71243741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63803
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
JHUEM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64722
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.955381
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218398
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23556
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41335
BRD-K86025005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16148
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15659
epithelial cell differentiation	GO Biological Process Annotations 2023	1.0	null
Nodular basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.25042
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95864
MFE-296	GDSC Cell Line Gene Expression Profiles	-1.0	-1.8448
propylthiouracil-4157	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6805
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32433
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260931
coated membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.09798
PMC3485261-pone.0046600.s008.docx-0-JAZAG_TGFB1__SIGNALING_VIA__SMAD4_UP_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01146
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5287
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16115
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11179
hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344574
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17691
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00652
trans-golgi network transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.65513
hsa-miR-3145-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
endomembrane system	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.792396
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66301
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964234
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7062-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C33A	DepMap CRISPR Gene Dependency	1.0	3.10104
cingulate gyrus, retrosplenial part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41828
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214366
3M complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24168
BRD-K11399565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09083
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18798
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964868
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31262
PANC1005	CCLE Cell Line Gene CNV Profiles	1.0	1.5127
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23028
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46351
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83843
doxylamine-1973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38361
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Retinol-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2013
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2308
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840588
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.954
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.950543
RH30	DepMap CRISPR Gene Dependency	1.0	2.9306
KRAS.50_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.794227
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059141
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04242
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.53098
BRD-K43495666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25103
sulfaguanidine-1913	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-519a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K39081386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06898
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16215
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31027
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915061
JUN-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72183943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52772
WB-4101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20516
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bleomycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61745
BRD-K35724671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03296
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
intermediate filament organization	GO Biological Process Annotations 2023	1.0	null
GSE195568_1_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Wnt signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.334
U343	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87966
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.73858
BRD-K96641838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14781
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01756
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23361
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56162
GSE135842_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52371
697	DepMap CRISPR Gene Dependency	1.0	3.80904
Perturb_6887_KO_PFDN5_SRP273783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.54008
TK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hexestrol-5776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K86925685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54517
PL45	CCLE Cell Line Gene CNV Profiles	1.0	2.03903
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.865577
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054812
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
Raji	GDSC Cell Line Gene Expression Profiles	1.0	1.71929
PMC9377669-tx1c00392_si_002.xlsx-Ranitidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902256
BRD-K51643438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37449
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7054
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
harpagoside-6636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5277
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.090882
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.39362
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9989
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-335	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K59626557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35656
BRD-K81647747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20736
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056555
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84407
BRD-K67120755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45145
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30387
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium development	GO Biological Process Annotations 2023	1.0	null
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27256
bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459532
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vitamin D receptor pathway	WikiPathways Pathways 2024	1.0	null
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	1.74017
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86662
BRD-K13301506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27495
BRD-K90103008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82424
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
cell communication	KEGG Pathways	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.667
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35869
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00255
PMC9377669-tx1c00392_si_002.xlsx-Entinostat-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08417
hsa-miR-4786-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852476
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48151
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4552
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
etifenin-2838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	3.24562
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548517
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21983
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95537
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73583
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4119
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03687
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23505
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47344
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054752
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.071013
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113276
intracellular part	GO Cellular Component Annotations 2015	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894843
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8272
hsa-miR-519b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K88369626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80859
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9689
Perturb_16426_KD_APP_SRP187586	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.40947
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.927533
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05327
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	2.70751
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.81373
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051907
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41972
clathrin vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56674
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56376
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.65472
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	3.24562
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.814
BRD-K37684893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60647
Phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
BRD-K97761115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73647
Coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9377669-tx1c00392_si_002.xlsx-Leflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0419
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.767
KYAE1	DepMap CRISPR Gene Dependency	1.0	16.7145
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21599
SK-LMS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K30937829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27071
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2206
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31993
bephenium hydroxynaphthoate-3089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEI-OC1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29132
zaprinast-1611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09018
20388125-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6032
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.55027
BRD-K13257316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60028
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84853
JJN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3931
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K07576726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14777
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51036
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31201
BRD-K99944747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68477
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06946
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19203
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40052
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057801
fleroxacin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20096
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3217
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.767
Developmental Biology	Reactome Pathways 2024	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.05022
CAL33	DepMap CRISPR Gene Dependency	1.0	4.96215
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09821
xylazine-4147	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083406
BRD-K75981692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02402
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970154
broxyquinoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39603
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.891434
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2159
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44879
BRD-A03121430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2196
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Magnesium_Cl-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42453497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25348
PMC9377669-tx1c00392_si_002.xlsx-5_5-Diphenylhydantoin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17328
BRD-K07420629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58169
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72539
hsa-miR-3064-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K48999921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44645
benfotiamine-4312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01076
BRD-K66030669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09481
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.782
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mpkCCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
tenoxicam-4182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45509
BRD-K93337444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04451
PMC9377669-tx1c00392_si_002.xlsx-Methorexate-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ap-1 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.65513
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344818
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869843
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21166
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24168
GSE114284_2_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
k29	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.103
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
Hair root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.087629
BRD-K25761766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08303
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4088
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114145
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954148
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56993
HDAC2	ENCODE Transcription Factor Targets	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896681
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5213
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21742
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6554
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995095
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29797
BRD-K92722247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43845
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	0.785071
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260931
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14127
BRD-A78355490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77721
Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Smooth muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEK_OE_GDS1925_165_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.14955
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26371
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.41535
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30374
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48654
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90602
metanephrine-2015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Doxylamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80358
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45984
hsa-miR-519c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13664
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053877
BRD-K78983822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75514
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7181
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40189164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42534
BRD-K17107214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05167
BRD-K91937280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21206
BRD-K58217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90889
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25072
SNU182	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6587
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10122
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42475
erastin-6364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STOCK1N-28457-6869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0183
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-L-Thyronine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1305	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.96789
COLO-741	GDSC Cell Line Gene Expression Profiles	-1.0	-1.61632
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29811
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K68884923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37202
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3217
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20203
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
short insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10187
PANC-03-27	GDSC Cell Line Gene Expression Profiles	-1.0	-2.10424
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03838
Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cotinine-5246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.789
golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.34828
BRD-K09405682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02138
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K55104181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74308
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45121
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K51608228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07835
BRD-K25846934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42921
BRD-K24393110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37522
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49689
H4K8ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5224
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16138
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81169
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2949
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15308
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867951
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K45894579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92135
hsa-miR-4633-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K84710243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34089
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.674315
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K41970046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22795
BRD-K61877191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35895
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemochromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
Head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948304
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
BRD-K76672145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04771
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.02875
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0093
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.00035
CDK4_knockdown_143_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.47507
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881379
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.003
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78336
MAFK	ENCODE Transcription Factor Targets	1.0	null
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.902
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.86244
PMC9377669-tx1c00392_si_002.xlsx-Methicilin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37259
endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.43444
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82179
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.886305
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	0.926817
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K54317642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01572
BRD-K21819164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82923
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14672
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861546
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.038587
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.96057
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63242
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.840105
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03134
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38118311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.634
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
PMC9377669-tx1c00392_si_002.xlsx-Famotidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.767
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38215
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9377669-tx1c00392_si_002.xlsx-Vismodegib-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28433349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29166
BRD-K34815008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03368
BRD-K25805580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12381
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0454
Perturb_8287_KD_DDX55_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.99552
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-1.00035
scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.768197
colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.522405
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40866
BRD-K36763492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05054
practolol-1587	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12594
BRD-K32282076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32253
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Perturb_5919_KD_KAP1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.28643
CAL-12T	GDSC Cell Line Gene Expression Profiles	1.0	1.52117
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54914
CRCGN010_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11054
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1937
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39328339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21972
intermediate filament cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2679
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9574
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SARS-CoV MA15_Day2-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70595
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53265
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33388
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34984
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.73839
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229032
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
BRD-K35953312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12338
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13563
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9616
BRD-K51546355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31266
DOHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K46936109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00091
CRCGN015_MCF10A.TP53.M_24H:B24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.63675
Adrenalgland	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7024
PMC9377669-tx1c00392_si_002.xlsx-TSA-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89541
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98795
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15914
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25852
BRD-K54262203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1003
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6628
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3263
BRD-A99445203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03449
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878712
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.785071
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.680697
BRD-A44990218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13159
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.7878
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834313
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4476
BRD-K45282766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85431
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33256
chlorzoxazone-2263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3666	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PancreaticIslet	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858575
golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.46326
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845888
BRD-K22672200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01058
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.15612
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972294
clorgiline-1604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clathrin-coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
CFPAC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87667
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	0.785071
COLO-680N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.74936
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03935
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11282
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84592
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24455
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05842
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49246
hsa-miR-3976	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
KRAS.300_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.722415
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-A67787745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25822
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054758
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845888
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998547
Hair follicle bulge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
PCI38	DepMap CRISPR Gene Dependency	1.0	4.45797
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92339
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839411
BRD-K92011556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6715
Awn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
H3K27me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H2228	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5457
BRD-K72335238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05238
BRD-K30071505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22619
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.93893
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829113
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051556
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07195
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04617
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4520b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0887
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.6022
BRD-K14863829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08352
r63	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.141
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.785071
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.18502
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KRAS.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.29348
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75372
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47357
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882417
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRD-mediated mRNA stability complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.204
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307757
HNF4G	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58963469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1592
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
YAPC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K64393896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0578
FOSL2	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5956
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0416
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48993
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08035
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49128
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
hs27	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
Papilloma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
PMC9377669-tx1c00392_si_002.xlsx-DPH-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5213
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.377738
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5156
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24132
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.058
NP8	DepMap CRISPR Gene Dependency	1.0	3.12789
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC10806738-mmc2.xlsx-Table_S2-Table_S2_Table_of_significantly_adjusted_p-valued_0_05_down-regulated_genes_log2FC_-1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.87681
6-benzylaminopurine-2313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91637
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2273
ap-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.43331
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01521
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4668
BRD-A55063801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45916
Eb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.13215
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9148
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.696026
Estrogen signaling pathway	KEGG Pathways 2026	1.0	null
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43583
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.875218
skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.29118
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81078
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
Monocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19977
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35055
colon	GTEx Tissue Gene Expression Profiles	-1.0	-0.99802
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64949
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23957028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39097
GI1	CCLE Cell Line Gene Expression Profiles	1.0	1.87765
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38766
EPS15	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02437
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871933
E2F1	ChEA Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76725
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49228
20068100-TableS5	GeneSigDB Published Gene Signatures	1.0	null
SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.28049
MSTO-211H	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42631
BRD-K17940097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16653
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.452261
BRD-K39396484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53422
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6873
raloxifene-5759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pimethixene-7468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RJ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
vagina	HPA Tissue Protein Expression Profiles	1.0	0.785071
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948304
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20438
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17169
OE33	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78787
nomifensine-1378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39421
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67296
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10449
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06857
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866239
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.975353
FOS	ENCODE Transcription Factor Targets	1.0	null
BRD-K56424158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28729
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.286245
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045724
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06329
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
flutamide-3803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7141-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basal node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.490024
C32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59153
heart muscle	HPA Tissue Protein Expression Profiles	1.0	0.785071
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14702
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94444134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11722
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8257
BRD-K95192796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12371
BRD-K48020855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49794
adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112613
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930262
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084537
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26713
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34242
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046765
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
BRD-A26343863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26555
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40725
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3561
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14353
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24954
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.752895
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4016
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.14761
Clathrin vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966831
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2288
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03915
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2623
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.245685
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gelsemine-4177	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Scalp	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928161
Sarcoma_SARC_TCGA-PC-A5DM-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17757
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.71532
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.058
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	1.0	2.60564
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02789
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.907079
GCIY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63901
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.78104
ticlopidine-4074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64059
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31572
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.785071
methapyrilene-1588	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
trans-golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.65272
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832338
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04015
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.48871
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15129
CRCGN014_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08374
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061464
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67642
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35452
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39379
BRD-K57724551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79115
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5044
hsa-miR-4451	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56219
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178877
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
TC138	DepMap CRISPR Gene Dependency	1.0	2.70087
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
clioquinol-5258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18058
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051602
BRD-K62325456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38841
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.942144
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.65415
enoxacin-1597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7689-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25798
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5551-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr17_41458889_T_C_b38	GTEx eQTL 2025	1.0	1.4478
rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487106
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.1383
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.693393
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.73419
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71312
hsa-miR-671-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
exemestane-165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869843
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246124
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053123
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68095
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45735
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.93446
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861546
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.52038
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06657
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26611
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13423
Pure hair and nail ectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.877089
BDCM	CCLE Cell Line Gene Expression Profiles	1.0	1.35542
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40289
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055116
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
HUH6	CCLE Cell Line Gene Expression Profiles	1.0	1.53942
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.77636
SF295	CCLE Cell Line Gene CNV Profiles	1.0	1.35179
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91637
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23529
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47014
Cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
BRD-K25638721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.026
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28919
GAIT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
BRD-K24246830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15104
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.776
chr17_41434932_G_A_b38	GTEx eQTL 2025	1.0	1.08799
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3651
hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.958585
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21635
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74824
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81997160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76063
BRD-K83715372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25141
BRD-K91282650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92483
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.09442
BRD-K93846199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55008
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.915844
minoxidil-1914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HT-29	GDSC Cell Line Gene Expression Profiles	1.0	1.98582
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17903
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.23319
protein complex	GO Cellular Component Annotations 2015	1.0	null
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28385
BRD-K05409106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06342
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23698
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20852
BRD-A15798299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14842
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930188
BRD-K25127909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38246
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
GSE135514_8_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40666
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.36348
SCC9	DepMap CRISPR Gene Dependency	1.0	3.81838
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915583
BRD-K95864593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16094
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32638
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087895
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00235
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6993
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70552
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33325
hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43385
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34598
BRD-K62017257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16157
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.534846
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34252
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.625206
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10998
BRD-K17245631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52799
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6428
Brain Lower Grade Glioma_LGG_TCGA-FG-8188-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71554049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85947
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58424
Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9338313-41467_2022_32034_MOESM4_ESM.xlsx-Control_HS_0-Table_S1_HSF1-interacting_proteins_enriched_upon_heat_shock_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22063616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69642
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47224
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.045896
disease	GWASdb SNP-Disease Associations	1.0	0.023725
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00912
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.977539
lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315366
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0073
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32145
oxybutynin-1551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03557
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02139
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1437	DepMap CRISPR Gene Dependency	1.0	4.03881
MEL270	DepMap CRISPR Gene Dependency	1.0	6.15231
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06946
Perturb_15449_OE_OVOL1_SRP026256	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63113
ESS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07014
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.008
demecarium bromide-1781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Androgenic alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
ap-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56219
nicergoline-5775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.879
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84593875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46592
ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16606
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68595406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23715
YWHAG	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	CCLE Cell Line Gene Expression Profiles	1.0	1.39386
BRD-K27226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27061
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0671
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833973
piperine-4830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21313369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40699
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65005311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22653
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.548583
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.74827
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3264
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19859
Keratin, type I	InterPro Predicted Protein Domain Annotations	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44335
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17736
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20021
BRD-K96144282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08337
PMC9377669-tx1c00392_si_002.xlsx-Folic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44624253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09561
Perturb_3910_KO_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.58721
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07794261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47698
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911435
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893295
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38956
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054716
BRD-K88292241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2097
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	14.3558
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.34831
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.936745
Perturb_7496_KD_EFTUD2_SRP192094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.55827
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3656
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K60080002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13274
adult testis	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17459
BRD-K95338817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54858
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36732
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04343
paclitaxel-2043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K20586104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21884
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23471
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16131
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.38958
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56219
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
PSN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50906
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.025785
BRD-K15280583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6213
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59168
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.388137
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34311
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.351
norfloxacin-1406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061075
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1943
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02287
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
NCI-H2291	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.95469
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895041
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930812
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1104
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836479
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Mononuclear cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18543
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89509
BRD-K86721033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91914
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.667
SNU423	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81756
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90491
BRD-K99727034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16196
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.21118
BRD-K91854399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16487
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061345
fetal membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079546
BRD-K52303942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31142
CRCGN010_HEPG2_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02077
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3879300-pone.0084292.s002.xlsx-SPD_dataset-Gene_symbol_HOXD13	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29562
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24674
HNF4A	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13645
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.10124
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.61392
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14108
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21001
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10902
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17068
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
BRD-K28329571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02695
organelle part	GO Cellular Component Annotations 2015	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34354
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4348
CL11	CCLE Cell Line Gene CNV Profiles	1.0	1.56179
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850117
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073977
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824782
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9646
BRD-K06399794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89458
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32983
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	2.20206
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12586
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26941
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052255
BRD-K79438478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14649
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977839
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050616
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66227
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56604
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K43336921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91683
LN18	DepMap CRISPR Gene Dependency	1.0	3.11713
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071427
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10387
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABL1_knockdown_144_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.45785
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.443689
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	2.3541
NOMO-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55107
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068505
BRD-K54881917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48048
skin	GTEx Tissue Gene Expression Profiles	1.0	2.1736
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07916
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02156
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BRD-K14476597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11172
BRD-K54549319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05977
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.90031
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42997
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	1.65935
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046361
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078045
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.01864
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15359
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.871933
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	5.76543
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAJI	DepMap CRISPR Gene Dependency	1.0	3.20852
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.19273
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34235
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13569
hematological	GAD High Level Gene-Disease Associations	1.0	0.293278
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.19387
cytotoxic t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02936
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55702
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904774
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04289
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60703
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06668
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848041
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.02212
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07865
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
superior rostral gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09484
rosiglitazone-369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7826
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59289
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.07359
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18726958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36104
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912592
bromocriptine-5665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16314
BRD-K07540687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24391
dementia	GWASdb SNP-Disease Associations	1.0	0.332342
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55W-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00801
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3283
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8319
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957108
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88486
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240636
hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.293694
hsa-miR-4760-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.338506
H3K9me3_U2OS_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999674
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31599
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
HSG	BioGPS Cell Line Gene Expression Profiles	1.0	1.4531
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86689
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87831
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1513
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.254017
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46909
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25072
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K35341092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28416
Mononuclear phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.2
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3652
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
A1207	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70422
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88464
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05693
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92787
BRD-K39794286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29194
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884675
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34691
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19409
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1952
betamethasone-dipropionate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38841
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1599
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73451
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.9
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50409
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72915
BRD-K80622681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49028
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827886
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3643
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.39564
MDAMB468	CCLE Cell Line Gene Expression Profiles	1.0	2.04607
CDK2_knockdown_146_GSE31912	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.39001
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64633