association dataset threshold value standardized value Hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27734 EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.64209 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26531 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null NKRF Pathway Commons Protein-Protein Interactions 1.0 null SNRNP27 Pathway Commons Protein-Protein Interactions 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Animal Mammary Neoplasms DisGeNET Gene-Phenotype Associations 1.0 null CDC5L Pathway Commons Protein-Protein Interactions 1.0 null Cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35371 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.927842 amygdalohippocampal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42377 A431 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1587 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39006 RPL18A Pathway Commons Protein-Protein Interactions 1.0 null MAP1LC3A Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-744 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intracellular part GO Cellular Component Annotations 2015 1.0 null RPF2 Pathway Commons Protein-Protein Interactions 1.0 null Respiratory Tract Infections CTD Gene-Disease Associations 1.0 1.29936 Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.54856 abnormality of the integument HPO Gene-Disease Associations 1.0 null MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.51037 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null focal dorsal hair loss MPO Gene-Phenotype Associations 1.0 null CCT3 Pathway Commons Protein-Protein Interactions 1.0 null C18orf32 Pathway Commons Protein-Protein Interactions 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.8914 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966335 Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871035 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11224 PPARA_agonist activation_GSE17250_475_mouse_Isolated hepatocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Dinoflagellate sulcus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.529 NEK1 Pathway Commons Protein-Protein Interactions 1.0 null abnormal conjugate eye movement HPO Gene-Disease Associations 1.0 null ALYREF Pathway Commons Protein-Protein Interactions 1.0 null ILF3 Pathway Commons Protein-Protein Interactions 1.0 null SRRT Pathway Commons Protein-Protein Interactions 1.0 null skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049338 NPM1 Pathway Commons Protein-Protein Interactions 1.0 null HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1077 CGTHW1 CCLE Cell Line Gene CNV Profiles -1.0 -1.85169 RPL19 Pathway Commons Protein-Protein Interactions 1.0 null GSE193993_1_v_3_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17407 EIF4A3 Pathway Commons Protein-Protein Interactions 1.0 null intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44895 Atopic dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 Hair root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.257 posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.892276 SNRPB Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01717 abnormality of hair growth rate HPO Gene-Disease Associations 1.0 null ZNF638 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hair follicle bulge stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.48 superficial stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06585 SMC1A Pathway Commons Protein-Protein Interactions 1.0 null TFG Pathway Commons Protein-Protein Interactions 1.0 null TOP1 Pathway Commons Protein-Protein Interactions 1.0 null adult ovary HPM Cell Type and Tissue Protein Expression Profiles -1.0 -1.17387 RSL1D1 Pathway Commons Protein-Protein Interactions 1.0 null RPS2 Pathway Commons Protein-Protein Interactions 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82434 LN-229 COSMIC Cell Line Gene Mutation Profiles 1.0 null Arrector pili muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.595 disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null RPL35A Pathway Commons Protein-Protein Interactions 1.0 null XRCC6 Pathway Commons Protein-Protein Interactions 1.0 null abnormality of the periorbital region HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KU812 DepMap CRISPR Gene Dependency 1.0 6.22532 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23239 SPI1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPZB Pathway Commons Protein-Protein Interactions 1.0 null dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PRDX2 Pathway Commons Protein-Protein Interactions 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9375 TP63 ChEA Transcription Factor Targets 1.0 null RPS5 Pathway Commons Protein-Protein Interactions 1.0 null Mammary Carcinoma DisGeNET Gene-Disease Associations 1.0 null SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91373 Mammary Neoplasms DisGeNET Gene-Phenotype Associations 1.0 null GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EXOSC4 Pathway Commons Protein-Protein Interactions 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.79499 abnormality of the pupil HPO Gene-Disease Associations 1.0 null HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.660338 Keratinocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.736 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PDCD6IP Pathway Commons Protein-Protein Interactions 1.0 null heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.16177 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.7772 PCNA Pathway Commons Protein-Protein Interactions 1.0 null Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.002 disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null HSPA4L Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null MESOV DepMap CRISPR Gene Dependency 1.0 3.02897 ATG4A Pathway Commons Protein-Protein Interactions 1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1077 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.140251 SEC23A Pathway Commons Protein-Protein Interactions 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19738 keratin filament GO Cellular Component Annotations 2015 1.0 null hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.39258 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.30056 OCIM2 DepMap CRISPR Gene Dependency 1.0 4.42078 hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26557 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 PFN2 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21176 RUVBL2 Pathway Commons Protein-Protein Interactions 1.0 null Thymic medullary epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.54 SLC25A13 Pathway Commons Protein-Protein Interactions 1.0 null CORL105 CCLE Cell Line Gene CNV Profiles -1.0 -1.9034 extracellular organelle GO Cellular Component Annotations 2015 1.0 null TAF15 Pathway Commons Protein-Protein Interactions 1.0 null MRPS11 Pathway Commons Protein-Protein Interactions 1.0 null colliculus superior Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04145 Transport vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.895 SUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.36457 RPL14 Pathway Commons Protein-Protein Interactions 1.0 null Vesiculobullous skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EEF1G Pathway Commons Protein-Protein Interactions 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null PFN1 Pathway Commons Protein-Protein Interactions 1.0 null Leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.09176 DKC1 Pathway Commons Protein-Protein Interactions 1.0 null developmental process GO Biological Process Annotations 2015 1.0 null hair TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.55843 RBM34 Pathway Commons Protein-Protein Interactions 1.0 null RAE1 Pathway Commons Protein-Protein Interactions 1.0 null SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 extracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GSE93124_0_v_1_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Central amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03092 ZC3HAV1L Pathway Commons Protein-Protein Interactions 1.0 null initiation GeneRIF Biological Term Annotations 1.0 null ENO1 Pathway Commons Protein-Protein Interactions 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.296773 SSBP1 Pathway Commons Protein-Protein Interactions 1.0 null PABPC4 Pathway Commons Protein-Protein Interactions 1.0 null TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DPF2 Pathway Commons Protein-Protein Interactions 1.0 null GABARAPL2 Hub Proteins Protein-Protein Interactions 1.0 null LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16002 PSMB1 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PATU8988S CCLE Cell Line Gene Expression Profiles 1.0 1.56085 SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.884912 KYSE450 CCLE Cell Line Gene CNV Profiles 1.0 1.57439 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RBM14 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.964859 Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 FOXK2 Pathway Commons Protein-Protein Interactions 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.999398 skmel31 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.739 lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24981 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26837 posteroventral (inferior) parietal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54274 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.62635 SERPINB3 Pathway Commons Protein-Protein Interactions 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15591 RPS17 Pathway Commons Protein-Protein Interactions 1.0 null AHSA1 Pathway Commons Protein-Protein Interactions 1.0 null Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormality of the anterior segment of the eye HPO Gene-Disease Associations 1.0 null HSPA1B Pathway Commons Protein-Protein Interactions 1.0 null AGS CCLE Cell Line Gene Expression Profiles 1.0 1.93446 epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 superficial gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34021 IGR37 CCLE Cell Line Gene CNV Profiles -1.0 -1.71863 Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04033 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.5189 PCBP1 Pathway Commons Protein-Protein Interactions 1.0 null Cataract DisGeNET Gene-Disease Associations 1.0 null abnormal hair quantity HPO Gene-Disease Associations 1.0 null PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6 Rummagene Transcription Factor Associations 2026 1.0 null Squamous cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.587 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61176 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21724 decreased subcutaneous adipose tissue amount MGI Mouse Phenotype Associations 2023 1.0 null G3BP1 Pathway Commons Protein-Protein Interactions 1.0 null striatum_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1827 HES6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5442 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.90059 amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68024 Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08333 GAPO syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.026 integument phenotype MPO Gene-Phenotype Associations 1.0 null GMPPA Pathway Commons Protein-Protein Interactions 1.0 null retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34054 hESC Derived CD184+ Endoderm Cultured Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.859623 abnormality of the globe HPO Gene-Disease Associations 1.0 null hsa-miR-3146 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 smallintestine BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.38836 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4493 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mucinoses DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.227 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15591 ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.6575 RPLP0 Pathway Commons Protein-Protein Interactions 1.0 null pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.041413 SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.567301 GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures 1.0 null dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.250663 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922124 DYNC1H1 Pathway Commons Protein-Protein Interactions 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.06506 abnormality of the lens HPO Gene-Disease Associations 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Griscelli syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 HEYA8 DepMap CRISPR Gene Dependency 1.0 2.50614 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45856 pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.373899 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.337406 outer SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08595 SERBP1 Pathway Commons Protein-Protein Interactions 1.0 null MTPN Pathway Commons Protein-Protein Interactions 1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10434 Mononuclear cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 FLNC Pathway Commons Protein-Protein Interactions 1.0 null abnormal gland morphology MPO Gene-Phenotype Associations 1.0 null PKP1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-548t TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Keratosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.295 FLG Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63754 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.284962 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 C2BBE1 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11224 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.979819 Integumentary system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 KMS34 CCLE Cell Line Gene CNV Profiles 1.0 1.63464 GARS Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.70988 ATG4B Pathway Commons Protein-Protein Interactions 1.0 null plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.539793 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15435 abnormal coat appearance MPO Gene-Phenotype Associations 1.0 null Hair medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.56 Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44086 Carcinomatosis DisGeNET Gene-Phenotype Associations 1.0 null raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42696 Achondrogenesis type II DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 ATG3 Pathway Commons Protein-Protein Interactions 1.0 null NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55O-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.929632 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRPF19 Pathway Commons Protein-Protein Interactions 1.0 null Tooth germ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.851 HEC265 CCLE Cell Line Gene CNV Profiles -1.0 -1.71841 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55524 Arsenic CTD Gene-Chemical Interactions 1.0 null Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0694 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05247 HNRNPA2B1 Pathway Commons Protein-Protein Interactions 1.0 null SRSF10 Pathway Commons Protein-Protein Interactions 1.0 null RPL37A Pathway Commons Protein-Protein Interactions 1.0 null KHSRP Pathway Commons Protein-Protein Interactions 1.0 null NEK9 Pathway Commons Protein-Protein Interactions 1.0 null COR-L32 COSMIC Cell Line Gene Mutation Profiles 1.0 null skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51002 Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF5A Pathway Commons Protein-Protein Interactions 1.0 null RBM15 Pathway Commons Protein-Protein Interactions 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.60052 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Stratum granulosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.901 r5 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10876 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.6474 Keratinization Reactome Pathways 2024 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TPR Pathway Commons Protein-Protein Interactions 1.0 null Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40825 PRKAA1 Pathway Commons Protein-Protein Interactions 1.0 null NIPSNAP1 Pathway Commons Protein-Protein Interactions 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.55263 Awn TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.438 Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.711 intermediate stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90961 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01187 PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21608 SMAD2-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null NME1 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 heterozygous GeneRIF Biological Term Annotations 1.0 null HNRNPDL Pathway Commons Protein-Protein Interactions 1.0 null SHMT1 Pathway Commons Protein-Protein Interactions 1.0 null RARB-27405468-CHIP-SEQ-BRAIN-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC70 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.672088 Integumentary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 Hypotrichosis 13 ClinVar Gene-Phenotype Associations 1.0 null abnormality of the uvea HPO Gene-Disease Associations 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 UNC80 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39182 extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09708 strabismus HPO Gene-Disease Associations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null MHHNB11 CCLE Cell Line Gene Expression Profiles -1.0 -1.81552 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.33455 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 IARS Pathway Commons Protein-Protein Interactions 1.0 null YWHAE Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4693-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 BAG4 Pathway Commons Protein-Protein Interactions 1.0 null SMAD3 ChEA Transcription Factor Targets 1.0 null PPA1 Pathway Commons Protein-Protein Interactions 1.0 null GSTP1 Pathway Commons Protein-Protein Interactions 1.0 null A427 DepMap CRISPR Gene Dependency 1.0 7.371 TRAP1 Pathway Commons Protein-Protein Interactions 1.0 null Hypotrichosis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.262 periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14039 medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.920682 Monocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.4358 SRSF5 Pathway Commons Protein-Protein Interactions 1.0 null rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21176 ACHN CCLE Cell Line Gene CNV Profiles 1.0 1.64681 TUBB1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1869 COSMIC Cell Line Gene Mutation Profiles 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null RPL18 Pathway Commons Protein-Protein Interactions 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43037 NCBP1 Pathway Commons Protein-Protein Interactions 1.0 null GSE138938_1_v_3_foxp2_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH596 CCLE Cell Line Gene CNV Profiles -1.0 -1.3218 SMAD3-18955504-HACAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HSP90AA2 Pathway Commons Protein-Protein Interactions 1.0 null ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.1768 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ?hypotrichosis 13 OMIM Gene-Disease Associations 1.0 null curly vibrissae MGI Mouse Phenotype Associations 2023 1.0 null Contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15 lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2824 single-organism cellular process GO Biological Process Annotations 2015 1.0 null abnormality of the posterior segment of the eye HPO Gene-Disease Associations 1.0 null PCI15A DepMap CRISPR Gene Dependency 1.0 2.21853 HS863T CCLE Cell Line Gene Expression Profiles -1.0 -1.8397 EWSR1 Pathway Commons Protein-Protein Interactions 1.0 null SNRPD1 Pathway Commons Protein-Protein Interactions 1.0 null Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54899 SF3A1 Pathway Commons Protein-Protein Interactions 1.0 null dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831276 Feather TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.985 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48461 Extracellular ferritin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.542 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.182 ATP5B Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LRRC15 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3665 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Autoimmune interstitial lung, joint, and kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.221 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.98 abnormal hypodermis morphology MPO Gene-Phenotype Associations 1.0 null COPS5 Pathway Commons Protein-Protein Interactions 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARS Pathway Commons Protein-Protein Interactions 1.0 null TIA1 Pathway Commons Protein-Protein Interactions 1.0 null TSR2 Pathway Commons Protein-Protein Interactions 1.0 null NCIH1693 CCLE Cell Line Gene CNV Profiles 1.0 1.87658 BUB3 Pathway Commons Protein-Protein Interactions 1.0 null NUDT21 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null keratin filament GO Cellular Component Annotations 2025 1.0 null ANAPC1 Pathway Commons Protein-Protein Interactions 1.0 null CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03183 SNCA_KO_GDS4153_530_mouse_striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SRSF9 Pathway Commons Protein-Protein Interactions 1.0 null rough coat MGI Mouse Phenotype Associations 2023 1.0 null ACAT1 Pathway Commons Protein-Protein Interactions 1.0 null cytoplasm GO Cellular Component Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EG-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.296773 m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55254 HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null SYNCRIP Pathway Commons Protein-Protein Interactions 1.0 null Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 disease GWASdb SNP-Disease Associations 1.0 0.031073 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.93458 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.253 A704 CCLE Cell Line Gene CNV Profiles 1.0 1.41732 TCF7L2 ENCODE Transcription Factor Targets 1.0 null H2AFV Pathway Commons Protein-Protein Interactions 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948542 Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08249 RPS8 Pathway Commons Protein-Protein Interactions 1.0 null PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1 Rummagene Transcription Factor Associations 2026 1.0 null bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047385 Learning Disorders CTD Gene-Disease Associations 1.0 1.33642 dermal papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.885015 SKRC31 DepMap CRISPR Gene Dependency 1.0 2.03096 RNA polymerase I upstream activating factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 Fundus of striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31698 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null LLGL1 Pathway Commons Protein-Protein Interactions 1.0 null PDCD6 Pathway Commons Protein-Protein Interactions 1.0 null RPL30 Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.923057 HNRNPUL2 Pathway Commons Protein-Protein Interactions 1.0 null Liver Diseases CTD Gene-Disease Associations 1.0 1.26359 multicellular organismal process GO Biological Process Annotations 2015 1.0 null PURA Pathway Commons Protein-Protein Interactions 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.344079 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.888137 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879991 LUC7L2 Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Thorax TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.389 fusiform gyrus, left, bank of the its Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.905971 HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46608 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.33996 SMAD3-18955504-HaCaT-human ChEA Transcription Factor Binding Site Profiles 1.0 null PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.170191 NCL Pathway Commons Protein-Protein Interactions 1.0 null PRPH Pathway Commons Protein-Protein Interactions 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1177 MYCBP2 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43534 Hair follicle epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.49 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893161 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.65551 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55352 LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Cornified envelope formation KEGG Pathways 2026 1.0 null DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Ichthyosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.23 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02609 Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17634 Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3022822-1471-2164-12-11-S10.XLS-Suppl_7_newLN229_SOX2_KO_MOCK_2-Unnamed_1_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.848246 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.978351 TGFBR1_activemutant_291_GSE14523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.67845 schizophrenia GWASdb SNP-Disease Associations 1.0 0.582607 lateral terminal nucleus of the accessory optic tract, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.085 GSU DepMap CRISPR Gene Dependency 1.0 5.05208 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.876952 adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.09176 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63754 single-organism process GO Biological Process Annotations 2015 1.0 null Medial amygdalar nucleus, posterodorsal part, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16385 intermediate stratum of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47227 HSD17B10 Pathway Commons Protein-Protein Interactions 1.0 null paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1177 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36565 GGH Pathway Commons Protein-Protein Interactions 1.0 null RPL26L1 Pathway Commons Protein-Protein Interactions 1.0 null KRT24 Pathway Commons Protein-Protein Interactions 1.0 null RPL38 Pathway Commons Protein-Protein Interactions 1.0 null SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null IRGQ Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.65884 SW1271 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO678 CCLE Cell Line Gene Expression Profiles 1.0 1.97857 TBC1D2B Pathway Commons Protein-Protein Interactions 1.0 null CUL9 Pathway Commons Protein-Protein Interactions 1.0 null DUT Pathway Commons Protein-Protein Interactions 1.0 null SMARCC2 Pathway Commons Protein-Protein Interactions 1.0 null FLCN Pathway Commons Protein-Protein Interactions 1.0 null Medial amygdalar nucleus, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98249 HYOU1 Pathway Commons Protein-Protein Interactions 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RPL10A Pathway Commons Protein-Protein Interactions 1.0 null GSE216988,GSE216989_0_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Stratum corneum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.561 PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS24 Pathway Commons Protein-Protein Interactions 1.0 null HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -2.02991 U2SURP Pathway Commons Protein-Protein Interactions 1.0 null l90 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50371 ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RPL34 Pathway Commons Protein-Protein Interactions 1.0 null lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867304 Disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 SEC24C Pathway Commons Protein-Protein Interactions 1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65188 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61323 TEX10 Pathway Commons Protein-Protein Interactions 1.0 null waved hair MPO Gene-Phenotype Associations 1.0 null UBA5 Pathway Commons Protein-Protein Interactions 1.0 null DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.75612 BMI1-19503595-MEFC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null HEKTE CCLE Cell Line Gene Expression Profiles -1.0 -1.52834 C14orf166 Pathway Commons Protein-Protein Interactions 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04609 SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00063 schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.495641 H1FX Pathway Commons Protein-Protein Interactions 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88086 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.230958 SAFB Pathway Commons Protein-Protein Interactions 1.0 null primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048478 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6479 hsa-miR-4652-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 RPS9 Pathway Commons Protein-Protein Interactions 1.0 null solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33261 aplasia/hypoplasia of the eyebrow HPO Gene-Disease Associations 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09754 Diphtheria DisGeNET Gene-Disease Associations 1.0 null abnormal skin morphology MPO Gene-Phenotype Associations 1.0 null PMC7914369-thnov11p3676s2.xls-BPTF-signature-geneId_BPTF Rummagene Transcription Factor Associations 2026 1.0 null NCIH1092 CCLE Cell Line Gene Expression Profiles -1.0 -2.14544 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.096024 macromolecular complex GO Cellular Component Annotations 2015 1.0 null AIFM1 Pathway Commons Protein-Protein Interactions 1.0 null Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.532 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15591 HSP90AB1 Pathway Commons Protein-Protein Interactions 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.83262 Combined deficiency of vitamin K-dependent clotting factors 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.124 Central amygdalar nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1177 primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.985787 CEBPA-26348894-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.920495 EIF4A1 Pathway Commons Protein-Protein Interactions 1.0 null Protonema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.564 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044824 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null CDSN Pathway Commons Protein-Protein Interactions 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068176 TTBK2 Pathway Commons Protein-Protein Interactions 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.698 MIF Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4653-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05087 YWHAQ Pathway Commons Protein-Protein Interactions 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.849 membrane-bounded vesicle GO Cellular Component Annotations 2015 1.0 null IQCB1 Pathway Commons Protein-Protein Interactions 1.0 null SNUC4 DepMap CRISPR Gene Dependency 1.0 3.63701 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 focal hair loss MGI Mouse Phenotype Associations 2023 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044806 Sparse Lateral Eyebrow DisGeNET Gene-Phenotype Associations 1.0 null CSTA Pathway Commons Protein-Protein Interactions 1.0 null THOC6 Pathway Commons Protein-Protein Interactions 1.0 null PRKDC Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CBP-20019798-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6293 RC-K8 COSMIC Cell Line Gene Mutation Profiles 1.0 null Marrow cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 core part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03896 SNRPF Pathway Commons Protein-Protein Interactions 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)_24Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.93013 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.974708 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.00616 desmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.475625 ATG7 Pathway Commons Protein-Protein Interactions 1.0 null Hippocampus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUL2 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26837 WDR77 Pathway Commons Protein-Protein Interactions 1.0 null Ameloblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.846 BEND5 Pathway Commons Protein-Protein Interactions 1.0 null EXOSC3 Pathway Commons Protein-Protein Interactions 1.0 null SSB Pathway Commons Protein-Protein Interactions 1.0 null NEC8 COSMIC Cell Line Gene Mutation Profiles 1.0 null ALL-SIL COSMIC Cell Line Gene Mutation Profiles 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RPS11 Pathway Commons Protein-Protein Interactions 1.0 null JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13961 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05302 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45401 HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null RBM12B Pathway Commons Protein-Protein Interactions 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NUP88 Pathway Commons Protein-Protein Interactions 1.0 null epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.20156 59M CCLE Cell Line Gene Expression Profiles 1.0 1.49562 cdx2_20696899_caco2_lof_human_gpl570_gse22572 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.0217 SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null mantle zone of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0422 GSE242083,GSE242098_3_v_5_med1_human RummaGEO Gene Perturbation Signatures -1.0 null attention deficit hyperactivity disorder GWASdb SNP-Disease Associations 1.0 0.665868 ZNF326 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.892123 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04433 U2AF2 Pathway Commons Protein-Protein Interactions 1.0 null stomach HPA Tissue Protein Expression Profiles 1.0 0.700005 D283MED DepMap CRISPR Gene Dependency 1.0 6.05298 RAB3GAP2 Pathway Commons Protein-Protein Interactions 1.0 null trunk TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null neuro2a BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959134 DARS Pathway Commons Protein-Protein Interactions 1.0 null Stomach Smooth Muscle Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.920369 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.36325 DDX5 Pathway Commons Protein-Protein Interactions 1.0 null ventral tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3246 NCIH1373 DepMap CRISPR Gene Dependency 1.0 4.63893 Photosensitive trichothiodystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948833 GSE149096_2_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3672 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 abnormal hair follicle inner root sheath morphology MPO Gene-Phenotype Associations 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46347 Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23046 hsa-miR-92b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 DOCK7 Pathway Commons Protein-Protein Interactions 1.0 null dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04056 CCBL2 Pathway Commons Protein-Protein Interactions 1.0 null KRT85 Pathway Commons Protein-Protein Interactions 1.0 null Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.117 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75454 GABARAPL2 Pathway Commons Protein-Protein Interactions 1.0 null abnormality of the vasculature HPO Gene-Disease Associations 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36565 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0977 EFO27 CCLE Cell Line Gene Expression Profiles 1.0 2.29982 PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32177 CCT7 Pathway Commons Protein-Protein Interactions 1.0 null GABARAP Pathway Commons Protein-Protein Interactions 1.0 null ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.814 abnormality of eye movement HPO Gene-Disease Associations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UC-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC16A1 Pathway Commons Protein-Protein Interactions 1.0 null Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PFSK1 DepMap CRISPR Gene Dependency 1.0 5.81163 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22863 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53878 keratin filament COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 skin GTEx Tissue Gene Expression Profiles 1.0 2.18987 hyperactivity GWASdb SNP-Phenotype Associations 1.0 0.569663 Allergic contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.164 496100522_PCx_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.41436 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11146 HSPA6 Pathway Commons Protein-Protein Interactions 1.0 null PHGDH Pathway Commons Protein-Protein Interactions 1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Wooly Hair DisGeNET Gene-Phenotype Associations 1.0 null members GeneRIF Biological Term Annotations 1.0 null Integumentary system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Natural killer cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.108 Blood microparticle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.656 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898309 SMAD2 ChEA Transcription Factor Targets 1.0 null TEFM Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.072951 HUNS1 DepMap CRISPR Gene Dependency 1.0 2.58973 KRT6C Pathway Commons Protein-Protein Interactions 1.0 null SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MMP2 Pathway Commons Protein-Protein Interactions 1.0 null DDX20 Pathway Commons Protein-Protein Interactions 1.0 null paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05228 GSE193258,GSE193259_2_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH2073 CCLE Cell Line Gene CNV Profiles 1.0 2.37777 FTSJ3 Pathway Commons Protein-Protein Interactions 1.0 null PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNRNP70 Pathway Commons Protein-Protein Interactions 1.0 null Skin cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 hsa-miR-3192 TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05126 P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KAP1-22055183-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 AAMP Pathway Commons Protein-Protein Interactions 1.0 null ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8125 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1018 PCBD1 Pathway Commons Protein-Protein Interactions 1.0 null DDX3X Pathway Commons Protein-Protein Interactions 1.0 null Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 specialized GeneRIF Biological Term Annotations 1.0 null hsa-miR-1321 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 hsa-miR-940 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C1QBP Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRH2 Pathway Commons Protein-Protein Interactions 1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6715 ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044717 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38675 19036130-TableS1b GeneSigDB Published Gene Signatures 1.0 null PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R174L-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null woolly GeneRIF Biological Term Annotations 1.0 null RPL3 Pathway Commons Protein-Protein Interactions 1.0 null parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14497 Desmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.545 Mammary Neoplasms, Animal CTD Gene-Disease Associations 1.0 2.88009 GSE149096_4_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CLTC Pathway Commons Protein-Protein Interactions 1.0 null Subparafascicular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20523 MTHFD1L Pathway Commons Protein-Protein Interactions 1.0 null CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CORO1C Pathway Commons Protein-Protein Interactions 1.0 null Brittle Hair DisGeNET Gene-Disease Associations 1.0 null TP53INP2_KO_GDS5053_544_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.167 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36724 Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 IRF4-20064451-CD4+T-MOUSE ChEA Transcription Factor Targets 2022 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17265 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.189 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0868 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null TRIM21 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.91494 Dermal papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.257 TMC1 Pathway Commons Protein-Protein Interactions 1.0 null SW954 DepMap CRISPR Gene Dependency 1.0 2.34557 DDX27 Pathway Commons Protein-Protein Interactions 1.0 null SW480 CCLE Cell Line Gene Expression Profiles 1.0 2.34106 Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15215 Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAZAP1 Pathway Commons Protein-Protein Interactions 1.0 null 496100565_FWM_probable Alzheimer's disease_TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15215 Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GLIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0316 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40826 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8393 KRT31 Pathway Commons Protein-Protein Interactions 1.0 null PACS1 Pathway Commons Protein-Protein Interactions 1.0 null enlarged sebaceous gland MPO Gene-Phenotype Associations 1.0 null ATP6V1G2 Pathway Commons Protein-Protein Interactions 1.0 null KRT2 Pathway Commons Protein-Protein Interactions 1.0 null alopecia, neurologic defects, and endocrinopathy syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.152 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35031 NZOV9 DepMap CRISPR Gene Dependency 1.0 2.55102 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.4129 fine hair HPO Gene-Disease Associations 1.0 null RPTN Pathway Commons Protein-Protein Interactions 1.0 null DHX15 Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72766 HT1376 CCLE Cell Line Gene Expression Profiles 1.0 1.58947 Superior colliculus, optic layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3659 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36727 RASSF5 Pathway Commons Protein-Protein Interactions 1.0 null whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.319863 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 Extracellular region COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 NUDT16L1 Pathway Commons Protein-Protein Interactions 1.0 null dorsomedial part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39327 greasy coat MGI Mouse Phenotype Associations 2023 1.0 null Vibrissa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.194 SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null JVM3 CCLE Cell Line Gene CNV Profiles 1.0 1.3926 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.276304 KRT33B Pathway Commons Protein-Protein Interactions 1.0 null hair cycle process GO Biological Process Annotations 2015 1.0 null ovary GTEx Tissue Gene Expression Profiles -1.0 -0.995527 SF3B3 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22672 magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.926461 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927471 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A7U6-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.09482 intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39048 liminal alar domain of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21831 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896316 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.204 hsa-miR-4325 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Scalp TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.431 intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26787 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CCT8 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054396 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876002 TTN Pathway Commons Protein-Protein Interactions 1.0 null Ethylnitrosourea CTD Gene-Chemical Interactions 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BRIX1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09889 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.49054 mediodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00283 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.60976 GBAS Pathway Commons Protein-Protein Interactions 1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 PANC1 CCLE Cell Line Gene Expression Profiles 1.0 1.41529 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.97647 abnormality of the cardiovascular system HPO Gene-Disease Associations 1.0 null Epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.203 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7031 CL-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null EB2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.999398 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RBM15B Pathway Commons Protein-Protein Interactions 1.0 null Alopecia DisGeNET Gene-Disease Associations 1.0 null CYP2C8 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HADHA Pathway Commons Protein-Protein Interactions 1.0 null RFC5 Pathway Commons Protein-Protein Interactions 1.0 null RBM3 Pathway Commons Protein-Protein Interactions 1.0 null GAR1 Pathway Commons Protein-Protein Interactions 1.0 null MDH2 Pathway Commons Protein-Protein Interactions 1.0 null RBMX Pathway Commons Protein-Protein Interactions 1.0 null HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null intermediate filament COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.09191 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08479 PPP2R2B Pathway Commons Protein-Protein Interactions 1.0 null orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898318 H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIMM50 Pathway Commons Protein-Protein Interactions 1.0 null Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9736 RPL8 Pathway Commons Protein-Protein Interactions 1.0 null Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 short attention span GWASdb SNP-Phenotype Associations 1.0 0.569663 Pilomatrixoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.129 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CPSF1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142210_11_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null F5 CCLE Cell Line Gene Expression Profiles -1.0 -1.78683 YAE1D1 Pathway Commons Protein-Protein Interactions 1.0 null ARG1 Pathway Commons Protein-Protein Interactions 1.0 null KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9375 hsa-miR-2964a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.848154 PHB2 Pathway Commons Protein-Protein Interactions 1.0 null ILF2 Pathway Commons Protein-Protein Interactions 1.0 null cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null abnormal vibrissa morphology MGI Mouse Phenotype Associations 2023 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.65432 cytoskeletal part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE206729_4_v_1_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null Hair shaft TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.689 molting cycle process GO Biological Process Annotations 2015 1.0 null GSE193993_1_v_2_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null TXN Pathway Commons Protein-Protein Interactions 1.0 null A3KAW DepMap CRISPR Gene Dependency 1.0 2.29959 Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34885 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.05187 Skin carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 Set3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.896 abnormality of head or neck HPO Gene-Disease Associations 1.0 null CLINT1 Pathway Commons Protein-Protein Interactions 1.0 null Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.997 integumentary system disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null XRCC5 Pathway Commons Protein-Protein Interactions 1.0 null 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.10147 Autoimmune disease of skin and connective tissue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910845 hair GeneRIF Biological Term Annotations 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866753 CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null A172 DepMap CRISPR Gene Dependency 1.0 4.02065 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55281 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64931 CCT2 Pathway Commons Protein-Protein Interactions 1.0 null BMI1-19503595-MEFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Geniculate group, dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00854 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876002 496100468_PCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.2537 TUBA4A Pathway Commons Protein-Protein Interactions 1.0 null Intermediate filament cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15435 developmental disorder of mental health GWASdb SNP-Disease Associations 1.0 0.129192 SLC25A3 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55254 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36565 macromolecular complex subunit organization GO Biological Process Annotations 2015 1.0 null specific developmental disorder GWASdb SNP-Disease Associations 1.0 0.156078 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0727 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null DHX30 Pathway Commons Protein-Protein Interactions 1.0 null Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.03641 EGR1 ChEA Transcription Factor Targets 1.0 null GRSF1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4753-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 FTO Pathway Commons Protein-Protein Interactions 1.0 null SRSF7 Pathway Commons Protein-Protein Interactions 1.0 null intermediate filament organization GO Biological Process Annotations 2025 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952657 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.13957 abnormality of the face HPO Gene-Disease Associations 1.0 null VMRC-LCD COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 supramolecular fiber organization GO Biological Process Annotations 2025 1.0 null RBM28 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845689 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86165 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99154 intermediate filament organization GO Biological Process Annotations 2015 1.0 null KRT78 Pathway Commons Protein-Protein Interactions 1.0 null PUF60 Pathway Commons Protein-Protein Interactions 1.0 null STRBP Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.90725 DDX24 Pathway Commons Protein-Protein Interactions 1.0 null inner GeneRIF Biological Term Annotations 1.0 null layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09398 PABPN1 Pathway Commons Protein-Protein Interactions 1.0 null RCC2 Pathway Commons Protein-Protein Interactions 1.0 null H1F0 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.12526 t60-adrenal_consensus MoTrPAC Rat Endurance Exercise Training 1.0 2.01275 CSNK2A1 Pathway Commons Protein-Protein Interactions 1.0 null LTV1 Pathway Commons Protein-Protein Interactions 1.0 null Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.85489 SMARCA4 Pathway Commons Protein-Protein Interactions 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.37934 TE-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE1026 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.41741 Slow-Growing Hair DisGeNET Gene-Phenotype Associations 1.0 null FOXK1 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22167 SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.42694 SPTBN1 Pathway Commons Protein-Protein Interactions 1.0 null PLEC Pathway Commons Protein-Protein Interactions 1.0 null USF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.476 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null RAB11FIP5 Pathway Commons Protein-Protein Interactions 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.34202 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NBR1 Pathway Commons Protein-Protein Interactions 1.0 null Posterior amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38675 abnormal hair shaft morphology MPO Gene-Phenotype Associations 1.0 null XPNPEP3 Pathway Commons Protein-Protein Interactions 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069082 Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43305 SU-DHL-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null NOM1 Pathway Commons Protein-Protein Interactions 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052129 PSPC1 Pathway Commons Protein-Protein Interactions 1.0 null Strabismus DisGeNET Gene-Disease Associations 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.032498 GMPS Pathway Commons Protein-Protein Interactions 1.0 null SNRNP200 Pathway Commons Protein-Protein Interactions 1.0 null GATA3-21878914-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.182 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06557 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 1.09176 CHD4 Pathway Commons Protein-Protein Interactions 1.0 null BCL2L2-PABPN1 Pathway Commons Protein-Protein Interactions 1.0 null KG1 CCLE Cell Line Gene CNV Profiles -1.0 -3.21046 PWP1 Pathway Commons Protein-Protein Interactions 1.0 null Keratin, type II InterPro Predicted Protein Domain Annotations 1.0 null NFKB1 Pathway Commons Protein-Protein Interactions 1.0 null Extracellular exosome COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 NCIH660 CCLE Cell Line Gene CNV Profiles 1.0 1.90765 GSE193351_4_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures 1.0 null hair follicle morphogenesis GO Biological Process Annotations 2015 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06341 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RASSF1 Pathway Commons Protein-Protein Interactions 1.0 null GSE206729_3_v_1_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null binding GO Molecular Function Annotations 2015 1.0 null RPL23 Pathway Commons Protein-Protein Interactions 1.0 null medial subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.26099 RBM39 Pathway Commons Protein-Protein Interactions 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 CALU3 CCLE Cell Line Gene CNV Profiles -1.0 -1.40541 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDUFA4 Pathway Commons Protein-Protein Interactions 1.0 null Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SPI1 ChEA Transcription Factor Targets 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null Steatocystoma multiplex DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62629 CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -2.10021 YWHAZ Pathway Commons Protein-Protein Interactions 1.0 null KBTBD6 Pathway Commons Protein-Protein Interactions 1.0 null single-multicellular organism process GO Biological Process Annotations 2015 1.0 null Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Carcinoma CTD Gene-Disease Associations 1.0 2.88009 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02886 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89024 19605494-TableS1 GeneSigDB Published Gene Signatures 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 1.09176 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.652 TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.0 abnormality of skin adnexa HPO Gene-Disease Associations 1.0 null hair shaft TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.83682 Hypotrichosis DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 496100483_FWM_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.67598 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59675 HPRT1 Pathway Commons Protein-Protein Interactions 1.0 null RPL28 Pathway Commons Protein-Protein Interactions 1.0 null Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08441 Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.45157 OVCA420 DepMap CRISPR Gene Dependency 1.0 6.38159 IMPDH2 Pathway Commons Protein-Protein Interactions 1.0 null ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8473 Epidermal cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.931 NSMAF Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma DisGeNET Gene-Disease Associations 1.0 null locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39591 TECR Pathway Commons Protein-Protein Interactions 1.0 null r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38675 15273739-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null NCOA7 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate filament GO Cellular Component Annotations 2015 1.0 null abnormality of the choroid HPO Gene-Disease Associations 1.0 null HNRNPH2 Pathway Commons Protein-Protein Interactions 1.0 null SEC24B Pathway Commons Protein-Protein Interactions 1.0 null SRSF3 Pathway Commons Protein-Protein Interactions 1.0 null Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14029 NCIH446 CCLE Cell Line Gene Expression Profiles -1.0 -1.94094 RPL10 Pathway Commons Protein-Protein Interactions 1.0 null Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 GLI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2683 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 slow-growing hair HPO Gene-Disease Associations 1.0 null cingulate gyrus, retrosplenial part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20662 RPL7L1 Pathway Commons Protein-Protein Interactions 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.397811 intermediate filament GO Cellular Component Annotations 2025 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sense organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.083 ANK2 Pathway Commons Protein-Protein Interactions 1.0 null Skin epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.409 orbital frontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830391 NCIH1105 CCLE Cell Line Gene CNV Profiles -1.0 -1.79236 FUS Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4769-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 sheath GeneRIF Biological Term Annotations 1.0 null TNRC6B Pathway Commons Protein-Protein Interactions 1.0 null FNIP1 Pathway Commons Protein-Protein Interactions 1.0 null orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.830286 Sparse And Thin Eyebrow DisGeNET Gene-Phenotype Associations 1.0 null Congenital hypotrichosis with juvenile macular dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.3 hsa-miR-4461 TargetScan Predicted Conserved microRNA Targets 1.0 0.226173 SAFB2 Pathway Commons Protein-Protein Interactions 1.0 null SYNCRIP_OE_GDS4596_85_human_SW480 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879991 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74619 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.537 Breast Cancer_Mammary Gland Tissue_GSE3744 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.43957 abnormality of the hair HPO Gene-Disease Associations 1.0 null PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null MAP1LC3B Hub Proteins Protein-Protein Interactions 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33211 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.983483 HSPE1 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01009 Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDX3 Pathway Commons Protein-Protein Interactions 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36057 H3K27me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null 496100349_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.00784 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07969 SNU-398 COSMIC Cell Line Gene Mutation Profiles 1.0 null CNN3 Pathway Commons Protein-Protein Interactions 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.864738 curly vibrissae MPO Gene-Phenotype Associations 1.0 null ATP1A1 Pathway Commons Protein-Protein Interactions 1.0 null SRP9 Pathway Commons Protein-Protein Interactions 1.0 null EXOSC2 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERH Pathway Commons Protein-Protein Interactions 1.0 null EXOSC1 Pathway Commons Protein-Protein Interactions 1.0 null PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74438 dominant GeneRIF Biological Term Annotations 1.0 null NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 58.1546 CHAGO-K-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2126 DepMap CRISPR Gene Dependency 1.0 2.75874 spectrin-associated cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.094 subpallial amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20737 GSE219274,GSE219276_3_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null UACC-257 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null Hypotrichosis 11 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.605 WDR5 Pathway Commons Protein-Protein Interactions 1.0 null attention deficit hyperactivity disorder GWASdb SNP-Phenotype Associations 1.0 0.569663 MAP1A Pathway Commons Protein-Protein Interactions 1.0 null Lymphoid tissue TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Incisor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.912 496100592_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29698 GSE164529_0_v_1_tamoxifen_human RummaGEO Drug Perturbation Signatures 1.0 null parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11344 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.03199 JM1 CCLE Cell Line Gene Expression Profiles 1.0 1.41695 thorax TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MATR3 Pathway Commons Protein-Protein Interactions 1.0 null IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.60275 eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083841 Hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.248 BCKDHA Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5775 CTNNB1-24651522-LGR5+-INTESTINAL-STEM-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate gray layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31591 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876002 Meibomian gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 Cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.93424 PRPF39 Pathway Commons Protein-Protein Interactions 1.0 null COV644 CCLE Cell Line Gene Expression Profiles 1.0 1.69762 intermediate part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09396 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.6579 Intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2 Rummagene Transcription Factor Associations 2026 1.0 null TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null LARP1 Pathway Commons Protein-Protein Interactions 1.0 null placenta BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.27634 PLOD3 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DNAJA2 Pathway Commons Protein-Protein Interactions 1.0 null ZNF510 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.71233 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922894 anatomical structure morphogenesis GO Biological Process Annotations 2015 1.0 null GLA Pathway Commons Protein-Protein Interactions 1.0 null interstitial nucleus of the posterior limb of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67061 EIF5A2 Pathway Commons Protein-Protein Interactions 1.0 null subthalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35759 19036130-TableS1a GeneSigDB Published Gene Signatures 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.15245 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8453 Birt-Hogg-Dube syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46778 SNU-216 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21588 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3162 SKM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.00246 SNRPC Pathway Commons Protein-Protein Interactions 1.0 null ATG16L1 Pathway Commons Protein-Protein Interactions 1.0 null UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1054 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.26213 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null LIM1215 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hypotrichosis 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.1 H357 DepMap CRISPR Gene Dependency 1.0 2.11205 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33284 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3436-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the fundus HPO Gene-Disease Associations 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CTPS1 Pathway Commons Protein-Protein Interactions 1.0 null SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5708 SNU1079 DepMap CRISPR Gene Dependency 1.0 2.08987 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34054 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7594 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63994 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36724 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nezelof syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 intermediate filament organization GO Biological Process Annotations 2023 1.0 null abnormal hair texture MPO Gene-Phenotype Associations 1.0 null HUH1 CCLE Cell Line Gene Expression Profiles 1.0 1.61723 PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null dorsomedial nucleus, terminal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01631 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.49947 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.31203 PRKCZ Pathway Commons Protein-Protein Interactions 1.0 null RPS23 Pathway Commons Protein-Protein Interactions 1.0 null GSE48812_8_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.837027 AAK1 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATP1A2 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05171 hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.891753 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33226 RPS14 Pathway Commons Protein-Protein Interactions 1.0 null Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49699 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54087 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25452 MM160113 DepMap CRISPR Gene Dependency 1.0 2.08015 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28142 abnormality of movement GWASdb SNP-Phenotype Associations 1.0 0.291335 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.1087 Hypopigmentation Of Hair DisGeNET Gene-Phenotype Associations 1.0 null TFAP2C JASPAR Predicted Transcription Factor Targets 1.0 null Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23 Rummagene Transcription Factor Associations 2026 1.0 null Ciliary pocket collar COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.892 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.954811 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52626 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EXOSC9 Pathway Commons Protein-Protein Interactions 1.0 null Naxos disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.352 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.501 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.979819 Hepatomegaly CTD Gene-Disease Associations 1.0 1.18226 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053453 enlarged sebaceous gland MGI Mouse Phenotype Associations 2023 1.0 null NCIH650 CCLE Cell Line Gene CNV Profiles 1.0 1.45274 abnormality of the vasculature of the eye HPO Gene-Disease Associations 1.0 null SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rough coat MPO Gene-Phenotype Associations 1.0 null Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4016 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 IRS4 Pathway Commons Protein-Protein Interactions 1.0 null SET Pathway Commons Protein-Protein Interactions 1.0 null Apicolateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.862 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76526 KRT13 Pathway Commons Protein-Protein Interactions 1.0 null abnormality of hair pigmentation HPO Gene-Disease Associations 1.0 null M band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.6 mantle zone of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09396 medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6391 STIP1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.48 Orbital area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05401 AMPD1 Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.02114 NCOA5 Pathway Commons Protein-Protein Interactions 1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26113 NB1 CCLE Cell Line Gene Expression Profiles 1.0 3.40797 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SPI1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Plant tumor tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.804 H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.27432 Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01484 KRT35 Pathway Commons Protein-Protein Interactions 1.0 null Midbrain, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09358 SLK Pathway Commons Protein-Protein Interactions 1.0 null Nucleus of the brachium of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46539 abnormal adipose tissue amount MPO Gene-Phenotype Associations 1.0 null RANBP2 Pathway Commons Protein-Protein Interactions 1.0 null Intermediate filament COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 HCT8 CCLE Cell Line Gene Expression Profiles 1.0 1.69298 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54087 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966335 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Wooly Hair DisGeNET Gene-Disease Associations 1.0 null adipose tissue phenotype MPO Gene-Phenotype Associations 1.0 null Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7858 RPLP2 Pathway Commons Protein-Protein Interactions 1.0 null RPL13 Pathway Commons Protein-Protein Interactions 1.0 null dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58856 membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Epidermal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.275 SF3B4 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4345-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUP Pathway Commons Protein-Protein Interactions 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.978611 PPP2CA Pathway Commons Protein-Protein Interactions 1.0 null Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06471 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.928686 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65577 including GeneRIF Biological Term Annotations 1.0 null primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09822 abnormality of the eye HPO Gene-Disease Associations 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.157578 Sebaceous gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.735 abnormality of the iris HPO Gene-Disease Associations 1.0 null H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KRT75 Pathway Commons Protein-Protein Interactions 1.0 null P4HB Pathway Commons Protein-Protein Interactions 1.0 null motif GeneRIF Biological Term Annotations 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null abnormality of the retina HPO Gene-Disease Associations 1.0 null PRDX1 Pathway Commons Protein-Protein Interactions 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.299569 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04332 ACTA2 Pathway Commons Protein-Protein Interactions 1.0 null Scalp TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HERC2 Pathway Commons Protein-Protein Interactions 1.0 null PANC0213 CCLE Cell Line Gene Expression Profiles -1.0 -1.87133 Polymeric cytoskeletal fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 root GeneRIF Biological Term Annotations 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.18859 GABARAP Hub Proteins Protein-Protein Interactions 1.0 null ALDH1B1 Pathway Commons Protein-Protein Interactions 1.0 null 496100611_FWM_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.21304 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30289 hsa-miR-4675 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 abnormal eye morphology HPO Gene-Disease Associations 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22167 Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.033 Neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.135 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.8684 PSMC4 Pathway Commons Protein-Protein Interactions 1.0 null PPP2R1A Pathway Commons Protein-Protein Interactions 1.0 null r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73269 abnormal hair cortex morphology MPO Gene-Phenotype Associations 1.0 null habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74483 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ebolavirus(EBOV)_3day_PBMCs_17725815_GSE8317 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.58449 HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null hairhypotrichosis GeneRIF Biological Term Annotations 1.0 null HIST1H2BL Pathway Commons Protein-Protein Interactions 1.0 null RPS15A Pathway Commons Protein-Protein Interactions 1.0 null Taurine dioxygenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.699 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null Other source TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.367 Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 abnormal hair follicle morphology MPO Gene-Phenotype Associations 1.0 null FOXH1-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CBS Pathway Commons Protein-Protein Interactions 1.0 null NUP214 Pathway Commons Protein-Protein Interactions 1.0 null PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null REC1 CCLE Cell Line Gene CNV Profiles 1.0 1.71374 CUL3 Pathway Commons Protein-Protein Interactions 1.0 null CTNNB1-24651522-LGR5+ INTESTINAL STEM CELL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47915 RI1 CCLE Cell Line Gene Expression Profiles 1.0 1.38117 MRPS14 Pathway Commons Protein-Protein Interactions 1.0 null EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2325 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12223 atopic dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.493122 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.21541 hsa-miR-4493 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58544 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBM22 Pathway Commons Protein-Protein Interactions 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5421 Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null LGALS3BP Pathway Commons Protein-Protein Interactions 1.0 null GM2A Pathway Commons Protein-Protein Interactions 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.1037 HNF4alpha_KO_GDS1916_168_mouse_Embryonic liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.32786 Abnormal Retinal Morphology DisGeNET Gene-Phenotype Associations 1.0 null cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21827 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.55417 thin skin MGI Mouse Phenotype Associations 2023 1.0 null Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 mantle zone of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21622 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0856 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Trichohepatoenteric syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.475 KEAP1 Pathway Commons Protein-Protein Interactions 1.0 null SNAI1_OE_GDS4596_344_human_SW480 - Colorectal cancer cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37436 HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.345558 Keratin filament COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTF2I Pathway Commons Protein-Protein Interactions 1.0 null Extracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 RNPS1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null trans-Golgi network transport vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.024 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PYGL Pathway Commons Protein-Protein Interactions 1.0 null Extracellular space COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 JcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17219 PPP1CC Pathway Commons Protein-Protein Interactions 1.0 null Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Anaplasia DisGeNET Gene-Disease Associations 1.0 null Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LSM2 Pathway Commons Protein-Protein Interactions 1.0 null abnormal hair follicle morphology MGI Mouse Phenotype Associations 2023 1.0 null Autosomal dominant woolly hair DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.104 helix GeneRIF Biological Term Annotations 1.0 null all GeneRIF Biological Term Annotations 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -2.22909 Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02152 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19805 SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null NONO Pathway Commons Protein-Protein Interactions 1.0 null Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.8164 PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null CCT6A Pathway Commons Protein-Protein Interactions 1.0 null dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05395 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39355 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.06294 HS229T CCLE Cell Line Gene Expression Profiles -1.0 -2.42117 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U343 CCLE Cell Line Gene CNV Profiles -1.0 -1.36348 KRT6A Pathway Commons Protein-Protein Interactions 1.0 null substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.944384 Hypotrichosis ClinVar Gene-Phenotype Associations 2025 1.0 null HNRNPM Pathway Commons Protein-Protein Interactions 1.0 null Osseous plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.652 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 SDHA Pathway Commons Protein-Protein Interactions 1.0 null NCIH2087 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 KRT5 Pathway Commons Protein-Protein Interactions 1.0 null GTPBP4 Pathway Commons Protein-Protein Interactions 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.183935 FBL Pathway Commons Protein-Protein Interactions 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.795282 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A9-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.061698 Carcinoma, Spindle-Cell DisGeNET Gene-Disease Associations 1.0 null abnormal coat/ hair morphology MPO Gene-Phenotype Associations 1.0 null RPL7 Pathway Commons Protein-Protein Interactions 1.0 null JHOS-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17407 ACTB Pathway Commons Protein-Protein Interactions 1.0 null cellular component organization GO Biological Process Annotations 2015 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865528 Sparse Hair DisGeNET Gene-Phenotype Associations 1.0 null KRT3 Pathway Commons Protein-Protein Interactions 1.0 null Atrichia with papular lesions DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.526 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69952 Hair follicle outer root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.236 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZC3H4 Pathway Commons Protein-Protein Interactions 1.0 null PDHB Pathway Commons Protein-Protein Interactions 1.0 null MAT2A Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.879772 MYBBP1A Pathway Commons Protein-Protein Interactions 1.0 null extracellular vesicle GO Cellular Component Annotations 2015 1.0 null U87MG CCLE Cell Line Gene Expression Profiles -1.0 -2.40193 Alopecia universalis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.146 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25872 TUBA1C Pathway Commons Protein-Protein Interactions 1.0 null NCI-SNU-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1725 MARS Pathway Commons Protein-Protein Interactions 1.0 null WDFY3 Pathway Commons Protein-Protein Interactions 1.0 null MAP4 Pathway Commons Protein-Protein Interactions 1.0 null RRS1 Pathway Commons Protein-Protein Interactions 1.0 null Corneocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.898 Perturb_9833_KD_TBX3_SRP122892 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.83446 DDX21 Pathway Commons Protein-Protein Interactions 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49138 HCC-33 COSMIC Cell Line Gene Mutation Profiles 1.0 null Esophagus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.556 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.92074 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null Intermediate filament protein InterPro Predicted Protein Domain Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.24927 NCIH1355 CCLE Cell Line Gene CNV Profiles 1.0 1.80069 abnormal white adipose tissue amount MPO Gene-Phenotype Associations 1.0 null PDIA3 Pathway Commons Protein-Protein Interactions 1.0 null Retina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.083 Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.746 Medial amygdalar nucleus, posterodorsal part, sublayer a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.36144 abnormality of the head HPO Gene-Disease Associations 1.0 null MTAP Pathway Commons Protein-Protein Interactions 1.0 null Trichodontoosseous syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.471 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YTHDC2 Pathway Commons Protein-Protein Interactions 1.0 null NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6993 KP2 CCLE Cell Line Gene CNV Profiles -1.0 -1.44173 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05702 HUH1 CCLE Cell Line Gene CNV Profiles 1.0 1.37594 abnormality of hair texture HPO Gene-Disease Associations 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.08163 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.924735 PSME3 Pathway Commons Protein-Protein Interactions 1.0 null hair medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.8672 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.247852 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00731 cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.082511 cell communication KEGG Pathways 1.0 null organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 PEF1 Pathway Commons Protein-Protein Interactions 1.0 null KRT6B Pathway Commons Protein-Protein Interactions 1.0 null CFL1 Pathway Commons Protein-Protein Interactions 1.0 null DSG1 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07105 AGL Pathway Commons Protein-Protein Interactions 1.0 null KRT16 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17219 periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01666 VIM Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4918-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3925 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.904 AGO3 Pathway Commons Protein-Protein Interactions 1.0 null vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75017 ENO2 Pathway Commons Protein-Protein Interactions 1.0 null Fine Hair DisGeNET Gene-Phenotype Associations 1.0 null Combined oxidative phosphorylation deficiency 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.101 CARM1 Pathway Commons Protein-Protein Interactions 1.0 null JEG-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CAD Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13271 HIST2H2BE Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Insulin dbGAP Gene-Trait Associations 1.0 0.157729 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21588 GPI Pathway Commons Protein-Protein Interactions 1.0 null PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null Basal cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.263 Eye TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.083 VMRCLCD CCLE Cell Line Gene CNV Profiles 1.0 2.09507 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4009 JAK2_druginhibition_168_GSE38335 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.807117 RPS19 Pathway Commons Protein-Protein Interactions 1.0 null focal dorsal hair loss MGI Mouse Phenotype Associations 2023 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null Skin cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 JHH-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.89785 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04332 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.297447 hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27415 Verrucous papilloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.406 PAM212 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.963 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.1552 SNU840 DepMap CRISPR Gene Dependency 1.0 4.19353 STK3 Pathway Commons Protein-Protein Interactions 1.0 null Apocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.083 POLR2E Pathway Commons Protein-Protein Interactions 1.0 null within GeneRIF Biological Term Annotations 1.0 null hsa-miR-4756-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.78967 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.691676 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.936856 DHX57 Pathway Commons Protein-Protein Interactions 1.0 null PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23 Rummagene Transcription Factor Associations 2026 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RPS10 Pathway Commons Protein-Protein Interactions 1.0 null KPNA2 Pathway Commons Protein-Protein Interactions 1.0 null ZCCHC11 Pathway Commons Protein-Protein Interactions 1.0 null EIF2AK2 Pathway Commons Protein-Protein Interactions 1.0 null CTSA Pathway Commons Protein-Protein Interactions 1.0 null AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24329 superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09281 extracellular vesicular exosome COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36956 18614019-TableS4d GeneSigDB Published Gene Signatures 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22167 hsa-miR-4739 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PPIA Pathway Commons Protein-Protein Interactions 1.0 null CUL4B Pathway Commons Protein-Protein Interactions 1.0 null CALR Pathway Commons Protein-Protein Interactions 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GART Pathway Commons Protein-Protein Interactions 1.0 null MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CHTOP Pathway Commons Protein-Protein Interactions 1.0 null lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13784 Urinary bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.083 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.92301 protein complex subunit organization GO Biological Process Annotations 2015 1.0 null intermediate filament cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null adrenal gland GTEx Tissue Gene Expression Profiles -1.0 -0.883372 Stratified epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.456 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876002 Shoot apical meristem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.667 NAP1L1 Pathway Commons Protein-Protein Interactions 1.0 null NCIH889 CCLE Cell Line Gene Expression Profiles 1.0 1.663 Lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.108 superior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08011 Hypotrichosis 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.034 CPSF6 Pathway Commons Protein-Protein Interactions 1.0 null RRP1 Pathway Commons Protein-Protein Interactions 1.0 null Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74007 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38169 molecular_function GO Molecular Function Annotations 2015 1.0 null HSPD1 Pathway Commons Protein-Protein Interactions 1.0 null 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.46182 DLAT Pathway Commons Protein-Protein Interactions 1.0 null HIST1H2AB Pathway Commons Protein-Protein Interactions 1.0 null RPS16 Pathway Commons Protein-Protein Interactions 1.0 null OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Trunk TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29396 Immune system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HSP90AB2P Pathway Commons Protein-Protein Interactions 1.0 null Mammary Neoplasms, Experimental CTD Gene-Disease Associations 1.0 2.88009 intermediate stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00992 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.195353 SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.83081 hsa-miR-762 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 abnormal hair follicle inner root sheath morphology MGI Mouse Phenotype Associations 2023 1.0 null Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.852426 hsa-miR-3650 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15435 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36565 TT COSMIC Cell Line Gene Mutation Profiles 1.0 null HSPA7 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64748 HSPH1 Pathway Commons Protein-Protein Interactions 1.0 null TROVE2 Pathway Commons Protein-Protein Interactions 1.0 null SAMHD1 Pathway Commons Protein-Protein Interactions 1.0 null GPC4 Pathway Commons Protein-Protein Interactions 1.0 null GSE48812_8_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null Posterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08333 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2815 Pigment granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.021 abnormal skin condition MPO Gene-Phenotype Associations 1.0 null Hair disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Cuticle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.03 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879991 KRT77 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.138079 superficial stratum of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25814 single-organism organelle organization GO Biological Process Annotations 2015 1.0 null WDR62 Pathway Commons Protein-Protein Interactions 1.0 null GSE213650_0_v_1_everolimus_human RummaGEO Drug Perturbation Signatures 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876002 EEF1B2 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4741 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_768_mouse_Skin - 7 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84094 NAP1L4 Pathway Commons Protein-Protein Interactions 1.0 null Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 UBA52 Pathway Commons Protein-Protein Interactions 1.0 null SQSTM1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mucous acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.627 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null MTHFD1 Pathway Commons Protein-Protein Interactions 1.0 null cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.1862 USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HG3 DepMap CRISPR Gene Dependency 1.0 2.09335 SNU216 CCLE Cell Line Gene CNV Profiles -1.0 -1.38594 TGM3 Pathway Commons Protein-Protein Interactions 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15469 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37686 Formation of the cornified envelope Reactome Pathways 2024 1.0 null IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.86136 FYCO1 Pathway Commons Protein-Protein Interactions 1.0 null TUBB2A Pathway Commons Protein-Protein Interactions 1.0 null differentially GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4759-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Palmoplantar keratosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.494 Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50371 GEO COSMIC Cell Line Gene Mutation Profiles 1.0 null KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54784 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 REST ENCODE Transcription Factor Targets 1.0 null HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.591581 JM1 CCLE Cell Line Gene CNV Profiles 1.0 2.55518 abnormal vibrissa morphology MPO Gene-Phenotype Associations 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54734 Sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.54 LGMN Pathway Commons Protein-Protein Interactions 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.977854 Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4441 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 IGROV1 DepMap CRISPR Gene Dependency 1.0 2.03318 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.856088 Hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.582 fs6 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 HAT1 Pathway Commons Protein-Protein Interactions 1.0 null ZNF784 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0193 PRPF6 Pathway Commons Protein-Protein Interactions 1.0 null SNRPA Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12695 F8 Pathway Commons Protein-Protein Interactions 1.0 null Large granular lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.108 HSD17B4 Pathway Commons Protein-Protein Interactions 1.0 null GATA3-24758297-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TSR1 Pathway Commons Protein-Protein Interactions 1.0 null urinary bladder HPA Tissue Protein Expression Profiles 1.0 1.09176 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.982031 HDAC1 ENCODE Transcription Factor Targets 1.0 null Lymphoid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.108 all HPO Gene-Disease Associations 1.0 null Kidney failure DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.189 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11963 TBC1D15 Pathway Commons Protein-Protein Interactions 1.0 null 496100626_FWM_no dementia_TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02586 RANBP6 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17416 T-cell immunodeficiency, congenital alopecia, and nail dystrophy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.196 rt1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.786 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null TCP1 Pathway Commons Protein-Protein Interactions 1.0 null LRRC47 Pathway Commons Protein-Protein Interactions 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03639 medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1429 HNRNPF Pathway Commons Protein-Protein Interactions 1.0 null GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.996581 GSE236003_0_v_3_ubr5_human RummaGEO Gene Perturbation Signatures 1.0 null RPS25 Pathway Commons Protein-Protein Interactions 1.0 null SRSF11 Pathway Commons Protein-Protein Interactions 1.0 null MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tooth enamel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.849 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null protein complex GO Cellular Component Annotations 2015 1.0 null Pupillary Abnormality DisGeNET Gene-Phenotype Associations 1.0 null RPL13A Pathway Commons Protein-Protein Interactions 1.0 null APOBEC3B Pathway Commons Protein-Protein Interactions 1.0 null GSE193993_0_v_3_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null IGF2BP2 Pathway Commons Protein-Protein Interactions 1.0 null HSDL2 Pathway Commons Protein-Protein Interactions 1.0 null TGM1 Pathway Commons Protein-Protein Interactions 1.0 null DNAJC7 Pathway Commons Protein-Protein Interactions 1.0 null Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LYAR Pathway Commons Protein-Protein Interactions 1.0 null PMC10025425-mmc3.xlsx-ADNP_CNCR1-gene_ADNP Rummagene Transcription Factor Associations 2026 1.0 null XRN2 Pathway Commons Protein-Protein Interactions 1.0 null intermediate filament-based process GO Biological Process Annotations 2015 1.0 null SH10TC CCLE Cell Line Gene Expression Profiles 1.0 1.88669 CCT5 Pathway Commons Protein-Protein Interactions 1.0 null SHI1 DepMap CRISPR Gene Dependency 1.0 5.26229 SNU2535 DepMap CRISPR Gene Dependency 1.0 2.60001 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00361 MDAMB134VI CCLE Cell Line Gene CNV Profiles 1.0 1.53419 MPP2 Pathway Commons Protein-Protein Interactions 1.0 null S100A9 Pathway Commons Protein-Protein Interactions 1.0 null GNL3 Pathway Commons Protein-Protein Interactions 1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null chorioretinal abnormality HPO Gene-Disease Associations 1.0 null Sebocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.294 cytoskeletal part GO Cellular Component Annotations 2015 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RPL21 Pathway Commons Protein-Protein Interactions 1.0 null basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06079 BMI1 ChEA Transcription Factor Targets 1.0 null SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36224 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.67055 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.979819 KRT82 Pathway Commons Protein-Protein Interactions 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.691522 CBR3 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.915057 LIN7A Pathway Commons Protein-Protein Interactions 1.0 null Cockayne syndrome B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.269 HPAFII CCLE Cell Line Gene CNV Profiles 1.0 1.71466 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36724 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 KRT1 Pathway Commons Protein-Protein Interactions 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.5068 PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63 Rummagene Transcription Factor Associations 2026 1.0 null SRPX Pathway Commons Protein-Protein Interactions 1.0 null STBD1 Pathway Commons Protein-Protein Interactions 1.0 null TRIM28 Pathway Commons Protein-Protein Interactions 1.0 null KRT9 Pathway Commons Protein-Protein Interactions 1.0 null MEC1 CCLE Cell Line Gene CNV Profiles -1.0 -2.52188 DPS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.945 FAU Pathway Commons Protein-Protein Interactions 1.0 null KRT80 Pathway Commons Protein-Protein Interactions 1.0 null SFPQ Pathway Commons Protein-Protein Interactions 1.0 null YBX1 Pathway Commons Protein-Protein Interactions 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -2.38613 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868405 DNAJA1 Pathway Commons Protein-Protein Interactions 1.0 null TUBB4B Pathway Commons Protein-Protein Interactions 1.0 null r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09243 HSP90AA1 Pathway Commons Protein-Protein Interactions 1.0 null Skin stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.484 Temporal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5722 HNRNPUL1 Pathway Commons Protein-Protein Interactions 1.0 null ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.8485 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37436 hsa-miR-4447 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 BCAS2 Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49066 autosomal GeneRIF Biological Term Annotations 1.0 null AGO2 Pathway Commons Protein-Protein Interactions 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null SRSF1 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.092 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911073 CL11 CCLE Cell Line Gene Expression Profiles 1.0 2.14194 hsa-miR-4472 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PAICS Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42274 HNRNPH3 Pathway Commons Protein-Protein Interactions 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0644 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -3.39417 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041798 Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30487 ZNF207 Pathway Commons Protein-Protein Interactions 1.0 null Frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.05 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XA-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.95873 Phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 GSE149035_7_v_0_hepacam_human RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4003 MSH6 Pathway Commons Protein-Protein Interactions 1.0 null Ectodermal dysplasia 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.652 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1077 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57065 scalp TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KRT14 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.288902 abnormal hair shaft morphology MGI Mouse Phenotype Associations 2023 1.0 null NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null hsa-miR-1291 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 496100305_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.97906 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.936447 NIP7 Pathway Commons Protein-Protein Interactions 1.0 null Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22898 PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR Rummagene Transcription Factor Associations 2026 1.0 null ae3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.878 cytoskeleton organization GO Biological Process Annotations 2015 1.0 null TPI1 Pathway Commons Protein-Protein Interactions 1.0 null GAPDH Pathway Commons Protein-Protein Interactions 1.0 null Scapula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.047 Vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 PSMB5 Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 RPL10L Pathway Commons Protein-Protein Interactions 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null superficial stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.085 UACC257 DepMap CRISPR Gene Dependency 1.0 4.94331 waved hair MGI Mouse Phenotype Associations 2023 1.0 null abnormal eye physiology HPO Gene-Disease Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12067 IGF2BP3 Pathway Commons Protein-Protein Interactions 1.0 null HADHB Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-1910 TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 intermediate tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34476 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MOV10 Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SRRM2 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-BatSRBD_60Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.00363 Hypotrichosis 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.402 intermediate filament cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.607818 HNRNPCL1 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01806 CL-40 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54784 Focal nonepidermolytic palmoplantar keratoderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.25319 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37213 Autosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.982 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16002 SMARCB1 Pathway Commons Protein-Protein Interactions 1.0 null GSE160817_7_v_8_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.82614 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.18957 abnormal coat appearance MGI Mouse Phenotype Associations 2023 1.0 null H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null hypotrichosis DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null A498 CCLE Cell Line Gene Expression Profiles 1.0 1.36281 focal hair loss MPO Gene-Phenotype Associations 1.0 null ROS50 DepMap CRISPR Gene Dependency 1.0 4.4782 GSE236003_1_v_3_ubr5_human RummaGEO Gene Perturbation Signatures 1.0 null Zic3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.8479 abnormality of the eyebrow HPO Gene-Disease Associations 1.0 null CSNK2A2 Pathway Commons Protein-Protein Interactions 1.0 null HCC515 DepMap CRISPR Gene Dependency 1.0 5.32379 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24104 LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07704 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell-cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.077882 SNRPD3 Pathway Commons Protein-Protein Interactions 1.0 null WBP2 Pathway Commons Protein-Protein Interactions 1.0 null DSP Pathway Commons Protein-Protein Interactions 1.0 null hair disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9171 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.946583 alopecia MPO Gene-Phenotype Associations 1.0 null nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.087116 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0 DDX17 Pathway Commons Protein-Protein Interactions 1.0 null GSE219274,GSE219276_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4598 adipose tissue GTEx Tissue Gene Expression Profiles 1.0 1.20379 Brain ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TMEM160 Pathway Commons Protein-Protein Interactions 1.0 null Blood TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 EJM CCLE Cell Line Gene CNV Profiles -1.0 -1.53765 Developmental Biology Reactome Pathways 2024 1.0 null hsa-miR-5096 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 KMS26 DepMap CRISPR Gene Dependency 1.0 2.30755 Apical meristem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.911 HSPA4 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21554 NCIH23 CCLE Cell Line Gene Expression Profiles 1.0 1.42487 PPP3CB Pathway Commons Protein-Protein Interactions 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08043 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pontocerebellar hypoplasia type 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.195 vesicle GO Cellular Component Annotations 2015 1.0 null ventrolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07671 EZH2 ENCODE Transcription Factor Targets 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Melanocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.445 HSPA5 Pathway Commons Protein-Protein Interactions 1.0 null Trichome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.697 HEC1 DepMap CRISPR Gene Dependency 1.0 2.59621 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.46621 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932977 DYX1C1 Pathway Commons Protein-Protein Interactions 1.0 null macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ciliary pocket COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.723 Monilethrix DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.178 CAKI1 CCLE Cell Line Gene Expression Profiles -1.0 -1.86993 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.32109 hippocampus (hippocampal formation)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46171 Waardenburg syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 RPS18 Pathway Commons Protein-Protein Interactions 1.0 null Maple syrup urine disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.03 E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Bullous congenital ichthyosiform erythroderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mononuclear phagocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 CLTCL1 Pathway Commons Protein-Protein Interactions 1.0 null GSE164529_0_v_3_tamoxifen_human RummaGEO Drug Perturbation Signatures 1.0 null Melanocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.588 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24499 ACACA Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05317 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSP90B1 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61323 MCCC2 Pathway Commons Protein-Protein Interactions 1.0 null hematopoietic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10396 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.851697 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70364 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.63754 TIAL1 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08549 Null cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.108 19192944-TableS4 GeneSigDB Published Gene Signatures 1.0 null Osteogenesis imperfecta type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.152 Thymus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 abnormality of the ocular region HPO Gene-Disease Associations 1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40117 REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083283 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65016 hsa-miR-2355-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 t70-white-adipose_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.82323 Infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.27 SU-DHL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.783 RPL27 Pathway Commons Protein-Protein Interactions 1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null PRPF38B Pathway Commons Protein-Protein Interactions 1.0 null ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null CTNNB1 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAP7D1 Pathway Commons Protein-Protein Interactions 1.0 null Hemidesmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.111 Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Extracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GSE217541,GSE217543_3_v_2_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null GLIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.8038 Limbic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0516 FAM98A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPF8 Pathway Commons Protein-Protein Interactions 1.0 null PCMT1 Pathway Commons Protein-Protein Interactions 1.0 null Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.956685 DDX1 Pathway Commons Protein-Protein Interactions 1.0 null EIF6 Pathway Commons Protein-Protein Interactions 1.0 null 769-P COSMIC Cell Line Gene Mutation Profiles 1.0 null MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36724 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14243 FAM91A1 Pathway Commons Protein-Protein Interactions 1.0 null FLG2 Pathway Commons Protein-Protein Interactions 1.0 null CANX Pathway Commons Protein-Protein Interactions 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.58771 ventrolateral part of alar m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21622 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null C8orf33 Pathway Commons Protein-Protein Interactions 1.0 null VSIG8 Pathway Commons Protein-Protein Interactions 1.0 null DHX36 Pathway Commons Protein-Protein Interactions 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.098319 Squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 Medial amygdalar nucleus, posterodorsal part, sublayer b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43626 PRKAG1 Pathway Commons Protein-Protein Interactions 1.0 null central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31429 whorled hair MPO Gene-Phenotype Associations 1.0 null HIST1H1C Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.77186 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39048 all GWASdb SNP-Phenotype Associations 1.0 0.032433 RPS20 Pathway Commons Protein-Protein Interactions 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866753 PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-97-SOX14_SOX14 Rummagene Transcription Factor Associations 2026 1.0 null medial amygdala, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43941 PLOD1 Pathway Commons Protein-Protein Interactions 1.0 null DLST Pathway Commons Protein-Protein Interactions 1.0 null Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.117 SPTAN1 Pathway Commons Protein-Protein Interactions 1.0 null anterior paraventricular nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27924 reticular formation of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90961 RFC2 Pathway Commons Protein-Protein Interactions 1.0 null GFAP Pathway Commons Protein-Protein Interactions 1.0 null PMC8192774__F3 PFOCR Pathway Figure Associations 2024 1.0 null primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72333 FLNB Pathway Commons Protein-Protein Interactions 1.0 null WDR48 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H2087 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 YBX3 Pathway Commons Protein-Protein Interactions 1.0 null digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 hsa-miR-4654 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Familial woolly hair syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.762 MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -2.15744 dorsal paracommissural tectal nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06698 Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormal hair growth MPO Gene-Phenotype Associations 1.0 null non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.299569 NOP2 Pathway Commons Protein-Protein Interactions 1.0 null Urinary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.189 KLHL12 Pathway Commons Protein-Protein Interactions 1.0 null IPC298 CCLE Cell Line Gene Expression Profiles -1.0 -1.73722 Folliculitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.018 Hypotrichosis 8 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.347 hypopigmentation of hair HPO Gene-Disease Associations 1.0 null Lateral habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35489 RPL12 Pathway Commons Protein-Protein Interactions 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null DLD Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.0952 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.53555 GSE139455_4_v_5_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null DLD1 CCLE Cell Line Gene Expression Profiles 1.0 2.6408 thin skin MPO Gene-Phenotype Associations 1.0 null CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.873549 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21433 SMAD4 ChEA Transcription Factor Targets 1.0 null superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2517 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4015 alopecia MGI Mouse Phenotype Associations 2023 1.0 null CKB Pathway Commons Protein-Protein Interactions 1.0 null abnormality of the retinal vasculature HPO Gene-Disease Associations 1.0 null greasy coat MPO Gene-Phenotype Associations 1.0 null RPL31 Pathway Commons Protein-Protein Interactions 1.0 null Supramolecular polymer COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 KCNH2 Pathway Commons Protein-Protein Interactions 1.0 null YTHDF2 Pathway Commons Protein-Protein Interactions 1.0 null extracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 NEDD4 Pathway Commons Protein-Protein Interactions 1.0 null RPL15 Pathway Commons Protein-Protein Interactions 1.0 null Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00281 NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.35502 SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.92613 SMAD2-18955504-HACAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.608241 hsa-miR-4498 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30402 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null NUP210 Pathway Commons Protein-Protein Interactions 1.0 null IZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11363 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26115 HS888T CCLE Cell Line Gene Expression Profiles -1.0 -1.61392 ANKFY1 Pathway Commons Protein-Protein Interactions 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null Intermediate filament protein, conserved site InterPro Predicted Protein Domain Annotations 1.0 null Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.6296 RBM4B Pathway Commons Protein-Protein Interactions 1.0 null Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.485 abnormal hypodermis fat layer morphology MPO Gene-Phenotype Associations 1.0 null PEBP1 Pathway Commons Protein-Protein Interactions 1.0 null keratin GeneRIF Biological Term Annotations 1.0 null HNRNPD Pathway Commons Protein-Protein Interactions 1.0 null thymus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cSARS Bat SRBD_12Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.97794 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RCBTB1 Pathway Commons Protein-Protein Interactions 1.0 null TUBB Pathway Commons Protein-Protein Interactions 1.0 null PLRG1 Pathway Commons Protein-Protein Interactions 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15591 RPS4X Pathway Commons Protein-Protein Interactions 1.0 null SRY ChEA Transcription Factor Targets 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.970282 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.324 CENPJ Pathway Commons Protein-Protein Interactions 1.0 null Nonepidermolytic palmoplantar keratoderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.418 epithelial GeneRIF Biological Term Annotations 1.0 null Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48985 G3BP2 Pathway Commons Protein-Protein Interactions 1.0 null GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures -1.0 null TARDBP Pathway Commons Protein-Protein Interactions 1.0 null paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.896236 layers GeneRIF Biological Term Annotations 1.0 null PKM Pathway Commons Protein-Protein Interactions 1.0 null DGAT2L7P Pathway Commons Protein-Protein Interactions 1.0 null Hair follicle dermal papilla cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.586 E2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9866 DOK1 Pathway Commons Protein-Protein Interactions 1.0 null intermediate filament GO Cellular Component Annotations 2023 1.0 null UBE2L3 Pathway Commons Protein-Protein Interactions 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043449 Epidermolysis bullosa simplex DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.386 hsa-miR-548ah TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Posterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02779 SMARCC1 Pathway Commons Protein-Protein Interactions 1.0 null Sepsis_Splenocyte_GSE4479 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.59252 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969958 RPL24 Pathway Commons Protein-Protein Interactions 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null WM115 CCLE Cell Line Gene Expression Profiles -1.0 -1.70719 RPL5 Pathway Commons Protein-Protein Interactions 1.0 null SNU213 CCLE Cell Line Gene CNV Profiles -1.0 -1.3324 WM793 CCLE Cell Line Gene CNV Profiles -1.0 -2.3225 diphtheria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.682693 Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08333 GUCY2F Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2087 COSMIC Cell Line Gene Mutation Profiles 1.0 null PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.874025 TS-20 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.221 abnormal white adipose tissue morphology MPO Gene-Phenotype Associations 1.0 null keratin filament GO Cellular Component Annotations 2023 1.0 null NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.6837 Cargo receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.448 Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 extracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.057922 CCT4 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10522 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31698 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null Sparse Body Hair DisGeNET Gene-Phenotype Associations 1.0 null RKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04494 DSG4 Pathway Commons Protein-Protein Interactions 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.79377 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.339282 RBMXL2 Pathway Commons Protein-Protein Interactions 1.0 null RTCB Pathway Commons Protein-Protein Interactions 1.0 null cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.871309 OAT Pathway Commons Protein-Protein Interactions 1.0 null SRY-25088423-EMBRYONIC-GONADS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCIH1623 CCLE Cell Line Gene Expression Profiles 1.0 1.9555 integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.909787 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12128 POFUT2 Pathway Commons Protein-Protein Interactions 1.0 null GSE206729_2_v_1_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4369 RBBP4 Pathway Commons Protein-Protein Interactions 1.0 null PKBalpha_KO_GDS1784_194_mouse_Embryonic fibroblasts (MEFs) - 2h GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NUDT1 Pathway Commons Protein-Protein Interactions 1.0 null Waardenburg syndrome type 4C DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.201 NOC3L Pathway Commons Protein-Protein Interactions 1.0 null HUWE1 Pathway Commons Protein-Protein Interactions 1.0 null Epithalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98226 OVTOKO CCLE Cell Line Gene Expression Profiles 1.0 1.39184 TUFM Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17407 Prefoldin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.743 496100654_HIP_no dementia_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.37833 PMC8848980__F6 PFOCR Pathway Figure Associations 2024 1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6506 DNAJC10 Pathway Commons Protein-Protein Interactions 1.0 null SERPINH1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3156-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 abnormal skin adnexa morphology MPO Gene-Phenotype Associations 1.0 null A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23239 ALDH3A2 Pathway Commons Protein-Protein Interactions 1.0 null FASN Pathway Commons Protein-Protein Interactions 1.0 null GSE48812_8_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.95728 REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Chronic kidney disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.189 PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.72704 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4338 NCIH1573 DepMap CRISPR Gene Dependency 1.0 2.8233 COPB1 Pathway Commons Protein-Protein Interactions 1.0 null KHDRBS1 Pathway Commons Protein-Protein Interactions 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GRB2 Pathway Commons Protein-Protein Interactions 1.0 null ALB Pathway Commons Protein-Protein Interactions 1.0 null Hypotrichosis DisGeNET Gene-Disease Associations 1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39509 SW620 CCLE Cell Line Gene Expression Profiles -1.0 -1.52462 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null SEC23B Pathway Commons Protein-Protein Interactions 1.0 null Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.486 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948542 IQGAP2 Pathway Commons Protein-Protein Interactions 1.0 null SLC25A5 Pathway Commons Protein-Protein Interactions 1.0 null SQ1 CCLE Cell Line Gene Expression Profiles 1.0 1.7018 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.41795 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36565 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34495 horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.811056 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80741 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null Schopf-Schulz-Passarge syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 ACTBL2 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_16969_KD_AJUBA_SRP253076 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.78036 K2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SEC24A Pathway Commons Protein-Protein Interactions 1.0 null DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null Inner root sheath cell_Skin_Mouse CellMarker Gene-Cell Type Associations 1.0 null HSPA1L Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.847532 EEF1A2 Pathway Commons Protein-Protein Interactions 1.0 null KRT76 Pathway Commons Protein-Protein Interactions 1.0 null ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.88443 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02483 RFC4 Pathway Commons Protein-Protein Interactions 1.0 null LANCL1 Pathway Commons Protein-Protein Interactions 1.0 null MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3201 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TRIM45 Pathway Commons Protein-Protein Interactions 1.0 null Hair follicle neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.126 CSTB Pathway Commons Protein-Protein Interactions 1.0 null RCN2 Pathway Commons Protein-Protein Interactions 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36956 Fetal Kidney Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.05855 A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.2293 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35222 hsa-miR-4713-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09726 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8888 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60068 HCC15 DepMap CRISPR Gene Dependency 1.0 4.63244 GSE182179_0_v_1_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04946 Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.948542 GMDS Pathway Commons Protein-Protein Interactions 1.0 null Midline group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44318 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null TP53 JASPAR Predicted Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null MAP1LC3B Pathway Commons Protein-Protein Interactions 1.0 null ZCCHC8 Pathway Commons Protein-Protein Interactions 1.0 null Hypodermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.769 EEF2 Pathway Commons Protein-Protein Interactions 1.0 null PRDX4 Pathway Commons Protein-Protein Interactions 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.979322 SSR4 Pathway Commons Protein-Protein Interactions 1.0 null 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.02853 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null RPS3 Pathway Commons Protein-Protein Interactions 1.0 null structural molecule activity GO Molecular Function Annotations 2015 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.16857 extracellular vesicular exosome GO Cellular Component Annotations 2015 1.0 null PRMT1 Pathway Commons Protein-Protein Interactions 1.0 null TUBA3C Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.344 HNRNPL Pathway Commons Protein-Protein Interactions 1.0 null MCM3 Pathway Commons Protein-Protein Interactions 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17407 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null demonstration GeneRIF Biological Term Annotations 1.0 null phenotypic abnormality HPO Gene-Disease Associations 1.0 null Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 1.0 5.98335 Papilloma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.583 Hypotrichosis 7 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.537 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS13 Pathway Commons Protein-Protein Interactions 1.0 null GSE154350_1_v_0_ascl2_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38466 HSPB1 Pathway Commons Protein-Protein Interactions 1.0 null EXOSC10 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KRT27 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KRT10 Pathway Commons Protein-Protein Interactions 1.0 null extracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HNRNPA0 Pathway Commons Protein-Protein Interactions 1.0 null RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1 Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0341 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.64472 Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55025 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28467 RPL11 Pathway Commons Protein-Protein Interactions 1.0 null EEF1D Pathway Commons Protein-Protein Interactions 1.0 null DHX8 Pathway Commons Protein-Protein Interactions 1.0 null PDIA6 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5121-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRA2A Pathway Commons Protein-Protein Interactions 1.0 null Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Utricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60028 AGO1 Pathway Commons Protein-Protein Interactions 1.0 null AP-1 adaptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.025 C2BBE1 CCLE Cell Line Gene Expression Profiles 1.0 1.76668 Pure hair and nail ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.25 Melanosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.973 trans-Golgi network transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.006 RUVBL1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84I-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Moh TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.68 EFTUD2 Pathway Commons Protein-Protein Interactions 1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14104 PABPC1 Pathway Commons Protein-Protein Interactions 1.0 null COA6 Pathway Commons Protein-Protein Interactions 1.0 null cataract HPO Gene-Disease Associations 1.0 null MAP1LC3A Hub Proteins Protein-Protein Interactions 1.0 null H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 EBNA1BP2 Pathway Commons Protein-Protein Interactions 1.0 null abnormal adipose tissue morphology MPO Gene-Phenotype Associations 1.0 null PRDX6 Pathway Commons Protein-Protein Interactions 1.0 null DHX9 Pathway Commons Protein-Protein Interactions 1.0 null STK4 Pathway Commons Protein-Protein Interactions 1.0 null family GeneRIF Biological Term Annotations 1.0 null SRSF2 Pathway Commons Protein-Protein Interactions 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879991 TCF7L2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR Rummagene Transcription Factor Associations 2026 1.0 null TRIM41 Pathway Commons Protein-Protein Interactions 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32825 Vitamin D receptor pathway WikiPathways Pathways 2024 1.0 null NXF1 Pathway Commons Protein-Protein Interactions 1.0 null periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50845 NCIH524 CCLE Cell Line Gene Expression Profiles -1.0 -3.28747 DDX41 Pathway Commons Protein-Protein Interactions 1.0 null Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1696 DMS53 DepMap CRISPR Gene Dependency 1.0 4.15815 MRPS22 Pathway Commons Protein-Protein Interactions 1.0 null retina BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.273734 SRSF4 Pathway Commons Protein-Protein Interactions 1.0 null Epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.21 Hair TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.44 IRF6_KO_GDS2359_126_mouse_skin E17.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Supramolecular fiber COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 PAIP2 Pathway Commons Protein-Protein Interactions 1.0 null Clathrin coat of trans-Golgi network vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.024 nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57065 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966335 SNRPE Pathway Commons Protein-Protein Interactions 1.0 null OCUM1 DepMap CRISPR Gene Dependency 1.0 2.66102 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75649 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01708 extracellular region part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HSPA9 Pathway Commons Protein-Protein Interactions 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 supramolecular fiber organization GO Biological Process Annotations 2023 1.0 null endocrine/exocrine gland phenotype MPO Gene-Phenotype Associations 1.0 null neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067261 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4108 Hypotrichosis 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.781 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE157894_1_v_3_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null IGF2BP1 Pathway Commons Protein-Protein Interactions 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 RPS6 Pathway Commons Protein-Protein Interactions 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.424 woolly hair HPO Gene-Disease Associations 1.0 null EPRS Pathway Commons Protein-Protein Interactions 1.0 null organelle organization GO Biological Process Annotations 2015 1.0 null DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.39519 Skin carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.26 Mel-Ab cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNRPG Pathway Commons Protein-Protein Interactions 1.0 null Nonsyndromic congenital nail disorder 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.392 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.897276 JUND ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08118 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12697 hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 2.37896 AHCY Pathway Commons Protein-Protein Interactions 1.0 null Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2311 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31698 lateral dorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923162 GPC6 Pathway Commons Protein-Protein Interactions 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15726 nerve GTEx Tissue Gene Expression Profiles 1.0 0.892696 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20146 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.902364 superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27981 Basal cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 intermediate stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10953 PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR Rummagene Transcription Factor Associations 2026 1.0 null decreased subcutaneous adipose tissue amount MPO Gene-Phenotype Associations 1.0 null outer plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.703127 Nonsyndromic congenital nail disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 A4FUK CCLE Cell Line Gene CNV Profiles 1.0 2.20417 NUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 1.65072 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08764 Hairy root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.847 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PRKAR2A Pathway Commons Protein-Protein Interactions 1.0 null DDB1 Pathway Commons Protein-Protein Interactions 1.0 null GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07412 GTF3C3 Pathway Commons Protein-Protein Interactions 1.0 null DAP3 Pathway Commons Protein-Protein Interactions 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30505 intermediate stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22116 DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6159 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07704 PDXK Pathway Commons Protein-Protein Interactions 1.0 null EEF1A1 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98453 Alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.861 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874862 RPLP1 Pathway Commons Protein-Protein Interactions 1.0 null Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 RPL7A Pathway Commons Protein-Protein Interactions 1.0 null GSE193993_4_v_3_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null SCC9 CCLE Cell Line Gene CNV Profiles -1.0 -1.60557 MAP1B Pathway Commons Protein-Protein Interactions 1.0 null Methane monooxygenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.889 VRK1_knockout_64_GSE19329 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.87233 anchoring junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.161275 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.949882 Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12329 Brain Lower Grade Glioma_LGG_TCGA-HT-7475-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1016 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal cord TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.483 NCIH2087 DepMap CRISPR Gene Dependency 1.0 7.31545 DENND3 Pathway Commons Protein-Protein Interactions 1.0 null Supramolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 YLPM1 Pathway Commons Protein-Protein Interactions 1.0 null intermediate filament cytoskeleton organization GO Biological Process Annotations 2015 1.0 null mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null RNMT Pathway Commons Protein-Protein Interactions 1.0 null Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.914 RPL23A Pathway Commons Protein-Protein Interactions 1.0 null Stratum intermedium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.769 RFC1 Pathway Commons Protein-Protein Interactions 1.0 null HP1BP3 Pathway Commons Protein-Protein Interactions 1.0 null Thymic medullary epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.543 SF3B1 Pathway Commons Protein-Protein Interactions 1.0 null ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.721 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55953 SLC25A6 Pathway Commons Protein-Protein Interactions 1.0 null Hypohidrotic ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.395 COR-L303 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE158743_1_v_2_nfkbia_human RummaGEO Gene Perturbation Signatures -1.0 null insulin GAD Gene-Disease Associations 1.0 null abnormal sebaceous gland morphology MPO Gene-Phenotype Associations 1.0 null Hypotrichosis 13 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.798 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 3.21427 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.425924 U2AF1 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPAB Pathway Commons Protein-Protein Interactions 1.0 null magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50885 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879991 Cytosol COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Medial amygdalar nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22039 hsa-miR-4492 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 IQSEC1 Pathway Commons Protein-Protein Interactions 1.0 null GLO1 Pathway Commons Protein-Protein Interactions 1.0 null bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.38688 RPS7 Pathway Commons Protein-Protein Interactions 1.0 null Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4154-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.968595 PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1 Rummagene Transcription Factor Associations 2026 1.0 null whorled hair MGI Mouse Phenotype Associations 2023 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.077 PTPLAD1 Pathway Commons Protein-Protein Interactions 1.0 null SEC61A1 Pathway Commons Protein-Protein Interactions 1.0 null Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.7794 GRWD1 Pathway Commons Protein-Protein Interactions 1.0 null POLR1A Pathway Commons Protein-Protein Interactions 1.0 null heart muscle HPA Tissue Protein Expression Profiles 1.0 1.09176 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05981 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL36 Pathway Commons Protein-Protein Interactions 1.0 null nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.122 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.67902 SLVL DepMap CRISPR Gene Dependency 1.0 3.06272 EMTOKA DepMap CRISPR Gene Dependency 1.0 4.34091 MAP1S Pathway Commons Protein-Protein Interactions 1.0 null DYNC1LI1 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24952 Sebum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.091 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.953782 MYO1B Pathway Commons Protein-Protein Interactions 1.0 null HEC6 DepMap CRISPR Gene Dependency 1.0 3.90751 affected GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.205609 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.170616 Intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null DOK7 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6367 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62666 Premature aging_Skin fibroblast_GSE10123 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.81875 Pavement epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 reticular formation of p2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47227 bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.319909 RBBP6 Pathway Commons Protein-Protein Interactions 1.0 null IPO5 Pathway Commons Protein-Protein Interactions 1.0 null RPL22 Pathway Commons Protein-Protein Interactions 1.0 null Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.98697 single-organism developmental process GO Biological Process Annotations 2015 1.0 null abnormal hair cortex morphology MGI Mouse Phenotype Associations 2023 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01789 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 5.0 RPL4 Pathway Commons Protein-Protein Interactions 1.0 null SKIV2L2 Pathway Commons Protein-Protein Interactions 1.0 null 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27108 Organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.167 PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR Rummagene Transcription Factor Associations 2026 1.0 null LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HLA-B Pathway Commons Protein-Protein Interactions 1.0 null Gut TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.167 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48751 centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28476 CIZ1 Pathway Commons Protein-Protein Interactions 1.0 null Enamel organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.933 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.13957 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.58878 Hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.329 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50662 JAK1_druginhibition_166_GSE38335 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.807117 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02756 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.31005 AZGP1 Pathway Commons Protein-Protein Interactions 1.0 null SNU761 DepMap CRISPR Gene Dependency 1.0 2.72359 Dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 PMC10350077-media-7.xlsx-Microglia_P_LPS_All_Up_GO-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24235 SNCA_KO_GDS4153_445_mouse_Striatum - 21 month GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Oculocutaneous albinism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.039 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1092 extracellular region part GO Cellular Component Annotations 2015 1.0 null GSE242083,GSE242098_2_v_1_med1_human RummaGEO Gene Perturbation Signatures 1.0 null IGR39 CCLE Cell Line Gene CNV Profiles -1.0 -1.41995 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.237 Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PHB Pathway Commons Protein-Protein Interactions 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02436 Epidermolysis bullosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.029 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.79028 lymphoid tissue TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SDHB Pathway Commons Protein-Protein Interactions 1.0 null LC4-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null STRAP Pathway Commons Protein-Protein Interactions 1.0 null Extracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Enamel epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.135 Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1781 HDAC2 ENCODE Transcription Factor Targets 1.0 null 496100462_PCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.47617 outer SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931623 RPL6 Pathway Commons Protein-Protein Interactions 1.0 null Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.8512 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57602 intermediate stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32717 PRKCI Pathway Commons Protein-Protein Interactions 1.0 null mammalian phenotype MPO Gene-Phenotype Associations 1.0 null anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07297 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03161 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.7202