association dataset threshold value standardized value fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20056 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15729 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24452 ZBED2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3092 outer SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09588 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1246 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01449 BLOC-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.84 BICR10 DepMap CRISPR Gene Dependency 1.0 2.71484 NCIH446 DepMap CRISPR Gene Dependency 1.0 2.23737 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1569 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.3284 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31724 cellular_component GO Cellular Component Annotations 2015 1.0 null AMO1 DepMap CRISPR Gene Dependency 1.0 2.19349 EZH2 ENCODE Transcription Factor Targets 1.0 null TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0824 SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1802 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12563 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9566 HSC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.4246 SW579 DepMap CRISPR Gene Dependency 1.0 2.25907 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54583 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8301 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9467 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20823 CL11 DepMap CRISPR Gene Dependency 1.0 3.59036 SW626 DepMap CRISPR Gene Dependency 1.0 2.61524 SET2 CCLE Cell Line Gene CNV Profiles 1.0 2.01753 FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3322 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3139 ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2721 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53066 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8718 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97193 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7229 ZR-75-30 COSMIC Cell Line Gene CNV Profiles -1.0 -5.12655 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6702 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91953 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.85884 TT CCLE Cell Line Gene CNV Profiles -1.0 -1.52387 cytoskeletal part GO Cellular Component Annotations 2015 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11038 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27388 KPNYN DepMap CRISPR Gene Dependency 1.0 2.12736 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8486 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null NCIH2085 CCLE Cell Line Gene CNV Profiles -1.0 -2.10156 NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3048 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.980605 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6157 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.889 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76363 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4147 inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31156 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8054 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28218 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7511 epidermis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.920632 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49293 MAFK ENCODE Transcription Factor Targets 1.0 null 3-M syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.633 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9469 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4829 TRAPP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.751 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27913 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36068 NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.83043 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40294 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874111 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.893968 Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bladder GTEx Tissue Gene Expression Profiles 1.0 0.988363 Keratinization Reactome Pathways 2024 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7529 RMUGS CCLE Cell Line Gene CNV Profiles -1.0 -1.34186 VMRCLCD CCLE Cell Line Gene CNV Profiles -1.0 -1.76825 PL45 CCLE Cell Line Gene CNV Profiles -1.0 -1.36509 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.028015 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5965 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58579 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9165 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27913 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00318 CAPAN1 DepMap CRISPR Gene Dependency 1.0 9.71757 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00218 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.99154 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66961 Sacrospinalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.0 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.477 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59494 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MCC26 DepMap CRISPR Gene Dependency 1.0 2.34348 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.55 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.939491 Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.103 small intestine HPA Tissue Protein Expression Profiles 1.0 1.54787 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70773 YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6623 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CCC5 DepMap CRISPR Gene Dependency 1.0 2.7681 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.85342 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7615 cell part GO Cellular Component Annotations 2015 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27597 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.927056 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3413 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3002 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7038 TALL1 CCLE Cell Line Gene CNV Profiles 1.0 2.86909 CAL12T CCLE Cell Line Gene CNV Profiles 1.0 1.54522 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.55398 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00616 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03367 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.870746 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.861617 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9944 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874855 cytoskeletal part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94251 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1545 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6793 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.72138 Developmental Biology Reactome Pathways 2024 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.3903 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2498 POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7681 mania GWASdb SNP-Phenotype Associations 1.0 0.429318 duodenum HPA Tissue Protein Expression Profiles 1.0 1.54787 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6003 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990351 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.502816 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0169 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.22825 outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.870075 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33335 Brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 mood disorder GWASdb SNP-Disease Associations 1.0 0.26914 DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.299 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913467 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1032 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8004 metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NPHP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.766 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6145 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.874362 NCI-H2347 COSMIC Cell Line Gene Mutation Profiles 1.0 null Extrachromosomal circular DNA COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.885 NCIH1694 CCLE Cell Line Gene CNV Profiles 1.0 2.04211 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69102 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1111 temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20421 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15385 intermediate filament COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 organelle part GO Cellular Component Annotations 2015 1.0 null HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7246 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844728 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3521 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1045 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34674 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2481 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.88604 RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8056 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 1.05379 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2524 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34586 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6147 RMUGS DepMap CRISPR Gene Dependency 1.0 3.90682 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2849 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1673 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04247 EFE184 DepMap CRISPR Gene Dependency 1.0 2.13634 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.982 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14854 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1417 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48594 hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.984254 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.72176 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6158 BLOC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.74 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0837 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 BL70 DepMap CRISPR Gene Dependency 1.0 2.44498 LXF-289 COSMIC Cell Line Gene Mutation Profiles 1.0 null Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.892 ES8 DepMap CRISPR Gene Dependency 1.0 3.44372 inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09821 VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.930951 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.920632 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.742 Hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00209 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2318 SW403 DepMap CRISPR Gene Dependency 1.0 2.89862 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1962 COLO800 DepMap CRISPR Gene Dependency 1.0 3.02069 DB DepMap CRISPR Gene Dependency 1.0 5.04519 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50695 SUZ12 ENCODE Transcription Factor Targets 1.0 null OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971172 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21018 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928571 pontine nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50436 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.328 HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 2.66808 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4765 angular gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11642 PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.797 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01978 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30378 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mpkCCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.336 Phospholamban complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.035 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02768 CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13259 GID complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.929 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41022 polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15598 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.13638 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Extrachromosomal DNA COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.659 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6514 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18338 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4603 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.828874 TC138 DepMap CRISPR Gene Dependency 1.0 11.0117 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.862241 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RPMI-7951 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00616 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15729 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DMRTA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7585 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 Hair TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.83874 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79549 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.93924 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.65554 CMK CCLE Cell Line Gene CNV Profiles 1.0 1.87484 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.924 extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15729 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7533 BHT-101 COSMIC Cell Line Gene Mutation Profiles 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 POLR2AphosphoS2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03622 Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.994 Intraciliary transport particle A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.648 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928571 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94251 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958039 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42803 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.62534 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00318 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16151 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54191 SP in perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08673 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028032 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4033 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965629 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47574 AU565 DepMap CRISPR Gene Dependency 1.0 5.00629 paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00054 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.848864 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16775 MHH-PREB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.79549 KYO1 CCLE Cell Line Gene CNV Profiles 1.0 1.6107 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94251 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94251 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.778 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.973177 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8958 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50713 SP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910268 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.948324 CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.35266 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0635 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1257 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null IGR1 CCLE Cell Line Gene CNV Profiles -1.0 -1.32255 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41838 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47795 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.086773 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24451 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8207 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.84662 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72904 outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917585 Metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.997821 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59134 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.037742 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41969 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CHSA0108 COSMIC Cell Line Gene Mutation Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30218 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965629 intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65166 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13401 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.24364 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.908284 RT11284 CCLE Cell Line Gene CNV Profiles 1.0 1.39733 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1635 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70704 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0572 DOV13 CCLE Cell Line Gene CNV Profiles 1.0 1.52035 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5241 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89447 Hairy cell leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.211 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5831 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.997935 ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7459 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47574 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.5705 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.26452 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47444 HEL9217 DepMap CRISPR Gene Dependency 1.0 11.0093 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5246 MHHCALL2 CCLE Cell Line Gene CNV Profiles 1.0 1.68724 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06541 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.1711 protein complex GO Cellular Component Annotations 2015 1.0 null Dorsal claustrum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.77903 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hair root TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Hair root TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 EVSAT DepMap CRISPR Gene Dependency 1.0 7.4269 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10548 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0635 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CCK81 DepMap CRISPR Gene Dependency 1.0 2.27796 CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14199 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09529 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7576 gyrus rectus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30668 UMUC7 DepMap CRISPR Gene Dependency 1.0 2.69329 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3337 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861809 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.64186 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CMK115 CCLE Cell Line Gene CNV Profiles 1.0 2.22631 Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.635 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30007 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20914 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87543 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2267 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09762 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.911914 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8778 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20147 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9767 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3747 KD DepMap CRISPR Gene Dependency 1.0 2.43073 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5655 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32171 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.920632 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29662 MOGGCCM CCLE Cell Line Gene CNV Profiles 1.0 1.33866 cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2493 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59056 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 19.3037 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0564 EN DepMap CRISPR Gene Dependency 1.0 5.39972 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4776 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.87365 Mo-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.24 22RV1 DepMap CRISPR Gene Dependency 1.0 2.94998 Sarcoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.022 Ciliary base COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.695 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06541 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4627 TUHR10TKB CCLE Cell Line Gene CNV Profiles 1.0 1.57702 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06541 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.161 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58334 PLCPRF5 CCLE Cell Line Gene CNV Profiles 1.0 1.40721 H3K9me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9966 ABC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.927519 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0896 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857536 CTCF ENCODE Transcription Factor Targets 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4735 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52304 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.082863 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09572 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6843 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.861617 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8468 JEKO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76313 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5665 PTK7_knockdown_185_GSE50138 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.99144 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4656 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.889155 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNB75 CCLE Cell Line Gene CNV Profiles 1.0 1.33375 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28218 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2564 Keratin-associated protein, type6/8/16/19/20 InterPro Predicted Protein Domain Annotations 1.0 null KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.21166 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895607 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20147 SNU626 DepMap CRISPR Gene Dependency 1.0 3.68808 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6474 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5688 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.429318 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6114 H3K9me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24519 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966351 internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.963008 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.900586 Longissimus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.037 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9823 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.894989 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04867 PACADD188 DepMap CRISPR Gene Dependency 1.0 7.27123 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874111 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1687 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02767 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00218 CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14798 NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.89884 OC314 DepMap CRISPR Gene Dependency 1.0 2.34094 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3628 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2887 intermediate filament cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6772 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.35853 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35017 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13616 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966351 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01277 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7162 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58334 KLE CCLE Cell Line Gene CNV Profiles 1.0 1.33539 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.429 Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 3M complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.487 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.47811 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.999899 L363 DepMap CRISPR Gene Dependency 1.0 6.05258 VCAP CCLE Cell Line Gene CNV Profiles 1.0 1.70863 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4129 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87395 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14674 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.05047 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0213 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24519 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.927952 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SNU1076 CCLE Cell Line Gene CNV Profiles -1.0 -1.76348 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.33211 MLXIPL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7359 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.3987 HEC59 DepMap CRISPR Gene Dependency 1.0 4.55278 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3691 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17573 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.966351 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4008 COLO320 CCLE Cell Line Gene CNV Profiles -1.0 -2.35399 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7593 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.249674 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1257 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 G84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.859081 ventral claustrum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85393 POLR2A ENCODE Transcription Factor Targets 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05272 ISTMEL1 DepMap CRISPR Gene Dependency 1.0 2.65408 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 Joubert syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6319 TCF4 MotifMap Predicted Transcription Factor Targets 1.0 null Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9157 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32793 NCIH2887 DepMap CRISPR Gene Dependency 1.0 2.45913 disease GWASdb SNP-Disease Associations 1.0 0.02359 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858839 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7171 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22213 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99862 disease of mental health GWASdb SNP-Disease Associations 1.0 0.040361 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28721 OCUBM DepMap CRISPR Gene Dependency 1.0 3.48419 skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.976301 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null subiculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02391 NCIH2106 CCLE Cell Line Gene CNV Profiles 1.0 1.70147 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872111 RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5455 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5364 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48737 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.910853 outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.92714 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15287 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2588 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null inferior olive, dorsal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896028 depression GWASdb SNP-Phenotype Associations 1.0 0.346131 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844728 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1234 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5015 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4335 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00318 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12223 PATU8902 CCLE Cell Line Gene CNV Profiles -1.0 -1.62029 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.927519 precentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.833177 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.923906 hair TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 intracellular part GO Cellular Component Annotations 2015 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20914 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2514 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50713 intermediate filament GO Cellular Component Annotations 2015 1.0 null brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08909 Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.696 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.861617 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89447 ZR7530 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 NCIH1573 DepMap CRISPR Gene Dependency 1.0 4.06701 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.554 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.906858 JHH2 DepMap CRISPR Gene Dependency 1.0 2.15917 127399 DepMap CRISPR Gene Dependency 1.0 3.44108 X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14479 SNU387 CCLE Cell Line Gene CNV Profiles -1.0 -1.75501 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.57998 DBTRG05MG CCLE Cell Line Gene CNV Profiles 1.0 1.81847 KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.68386 RT112 CCLE Cell Line Gene CNV Profiles 1.0 1.73962 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5447 COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.36565 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.847779 HEL CCLE Cell Line Gene CNV Profiles 1.0 2.20959 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928571 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null inner CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.911769 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5809 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3562 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.887763 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4204 U2OS CCLE Cell Line Gene CNV Profiles 1.0 1.43058 BICR16 DepMap CRISPR Gene Dependency 1.0 2.54013 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853798 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9942 HCC366 CCLE Cell Line Gene CNV Profiles -1.0 -2.50559 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.966605 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80435 SCS214 DepMap CRISPR Gene Dependency 1.0 2.26882 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.964464 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.329 adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.847567 PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1257 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6495 PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.52816 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Epidermis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.7307 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.9079 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17712 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08973 macromolecular complex GO Cellular Component Annotations 2015 1.0 null