association dataset threshold value standardized value LMCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19843 RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null BLOC-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.75 PDIK1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2561 hsa-miR-3913-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.83176 SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.32677 nanog_16518401_mesc_lof_mouse_gpl1261_gds1824 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.177549 H2BK20ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null GSE193993_0_v_6_sstr2_human RummaGEO Gene Perturbation Signatures 1.0 null OSC20 DepMap CRISPR Gene Dependency 1.0 2.58448 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46413 NCI-H740 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4967-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -1.91337 TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1292 MNX1-26342078-MIN6-4N-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LAN-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cranioectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 HCC1428 CCLE Cell Line Gene CNV Profiles -1.0 -1.44713 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null C15orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87071 TAL1_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPNYN DepMap CRISPR Gene Dependency 1.0 2.75311 PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-HGG_MYCN_deletions-Extended_Data_Table_2_Significant_regions_of_DNA_copy-number_alterations_by_DNA_methylation_class_MYCN Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-346 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ICC2 DepMap CRISPR Gene Dependency 1.0 2.11003 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.7165 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5361 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5803 POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null SW403 DepMap CRISPR Gene Dependency 1.0 2.34965 CAKI2 CCLE Cell Line Gene Expression Profiles -1.0 -1.67708 PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6774 PBX3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-23a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29527 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9294 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24505 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7444 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.37665 TCF3 ENCODE Transcription Factor Targets 1.0 null NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7204 ZR7530 CCLE Cell Line Gene CNV Profiles -1.0 -1.68717 LXF289 DepMap CRISPR Gene Dependency 1.0 2.83028 DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0937 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.53363 hsa-miR-3662 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KS1 CCLE Cell Line Gene Expression Profiles 1.0 1.39925 cellular_component GO Cellular Component Annotations 2015 1.0 null ESR1 ENCODE Transcription Factor Targets 1.0 null RKO CCLE Cell Line Gene Expression Profiles 1.0 1.64645 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57287 GATA2_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.7821 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894209 hsa-miR-4486 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.967234 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6304 ZNF491 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11643 MDA-MB-468 COSMIC Cell Line Gene Mutation Profiles 1.0 null Colon muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.985 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.362 496100528_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 10.2295 MAFK ENCODE Transcription Factor Targets 1.0 null Familial woolly hair syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.065 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.13295 Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-3154 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22414 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.914835 PRDM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17615 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6111 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0409 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.1936 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71164 MHHES1 CCLE Cell Line Gene CNV Profiles -1.0 -2.05378 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24214 GSE175787_13_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null CORL88 CCLE Cell Line Gene CNV Profiles -1.0 -1.36601 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.1436 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30452 hsa-miR-4261 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860168 MYC ENCODE Transcription Factor Targets 1.0 null SLR26 CCLE Cell Line Gene Expression Profiles -1.0 -2.28986 Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.388 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40721 Ciliary pocket collar COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.717 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37921 SP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15227 EW16 DepMap CRISPR Gene Dependency 1.0 3.70247 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07236 macromolecular complex GO Cellular Component Annotations 2015 1.0 null GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5025 ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8424 HUPT3 CCLE Cell Line Gene CNV Profiles 1.0 1.46726 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4688 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20405 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7256 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.936 embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1175 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A4TM-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE51684,GSE51741_2_v_4_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC Rummagene Transcription Factor Associations 2026 1.0 null MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34416 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Infiltrating angiolipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.667 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2523 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.66851 OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.880349 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.487 GSE121319_1_v_0_gprc5a_human RummaGEO Gene Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86641 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8771 Ribonuclease H2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.764 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33399 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31269 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.39519 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53051 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74881 FOSL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07435 SREBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.1798 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.947 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7104 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.903189 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967591 RSF complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.747 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.862932 HCC1143 CCLE Cell Line Gene CNV Profiles -1.0 -1.57608 PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6406 H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44134 LN428 CCLE Cell Line Gene Expression Profiles -1.0 -1.70088 PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9677 NCIH1184 CCLE Cell Line Gene CNV Profiles 1.0 1.53528 BHLHE40 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4510 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 NCI-H292 COSMIC Cell Line Gene Mutation Profiles 1.0 null ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.043 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1286 Ellis-Van Creveld syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.025 ZNF397 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52813 NCIN87 CCLE Cell Line Gene CNV Profiles 1.0 2.59998 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30652 USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4441 Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 FOSL2 ENCODE Transcription Factor Targets 1.0 null HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3575 cytoskeletal part GO Cellular Component Annotations 2015 1.0 null MALME3M DepMap CRISPR Gene Dependency 1.0 2.05217 MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8891 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860168 NPHP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.676 hsa-miR-4640-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 CTNNB1-20460455-HCT116-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BICR18 CCLE Cell Line Gene Expression Profiles -1.0 -1.47238 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0954 UBXN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03898 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860168 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -2.16256 MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5744 GSE239844_1_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13993 SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0696 Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.70266 FBXO45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51507 hair cycle GO Biological Process Annotations 2015 1.0 null FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6763 REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1533 LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4734 H3K27me3_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-CH2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE116492,GSE116495_3_v_2_stag2_human RummaGEO Gene Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.8714 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925995 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 USF1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1024 NPIPB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31099 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3844 GSE176144_0_v_1_zfc3h1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921362 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4059 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6615 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null kidney GTEx Tissue Gene Expression Profiles 1.0 0.868096 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Intraciliary transport particle A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 hsa-miR-4276 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null OV7 DepMap CRISPR Gene Dependency 1.0 2.33685 BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7852 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0538 LU99 CCLE Cell Line Gene Expression Profiles 1.0 2.92003 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.38034 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.31642 SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34209 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15757 Lung adenocarcinoma_LUAD_TCGA-55-8302-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04246 hsa-miR-4726-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00844 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6384 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1902 Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFPAC1 CCLE Cell Line Gene CNV Profiles 1.0 1.49392 EN DepMap CRISPR Gene Dependency 1.0 2.31022 POLR2A ENCODE Transcription Factor Targets 1.0 null ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.1384 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -2.05816 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57287 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-489 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LIM1215 COSMIC Cell Line Gene Mutation Profiles 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 LOXIMVI CCLE Cell Line Gene Expression Profiles 1.0 1.71334 GSE48812_11_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null PGM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84771 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4478 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8599 CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4286 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 skin GTEx Tissue Gene Expression Profiles 1.0 2.18987 Infiltrating lipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.409 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2641 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.68148 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC56 CCLE Cell Line Gene Expression Profiles -1.0 -1.4795 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6868 NIHOVCAR3 DepMap CRISPR Gene Dependency 1.0 2.45882 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2288 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.860852 SKMEL19 DepMap CRISPR Gene Dependency 1.0 2.10565 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5169 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.122 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76835 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8777 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6627 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.4975 Retinitis pigmentosa 11 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 hsa-miR-4422 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 light-harvesting complex, peripheral complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.037 Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EW22 DepMap CRISPR Gene Dependency 1.0 2.45755 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CADOES1 CCLE Cell Line Gene Expression Profiles 1.0 1.89417 RPMI-8226 COSMIC Cell Line Gene Mutation Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22414 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.803 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31378 CHP212 CCLE Cell Line Gene CNV Profiles 1.0 1.75022 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null HSF1-23293686-STHDH_STRIATAL-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46272 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.73366 U118MG DepMap CRISPR Gene Dependency 1.0 2.45336 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4287 organelle part GO Cellular Component Annotations 2015 1.0 null POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6742 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10290283-biol-2022-0622-sm3.pdf-21-HOXB1_HOXB1 Rummagene Transcription Factor Associations 2026 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.40115 ESR1_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00969 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9912 epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 developmental process GO Biological Process Annotations 2015 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.573689 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925995 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9564 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2246 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15891 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8492 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7697 hsa-miR-1182 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 COQ6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9681 Plasma membrane light-harvesting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.942 Split hand-foot malformation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388 mediodorsal nucleus of thalamus_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.860656 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1897 CCLE Cell Line Gene Expression Profiles -1.0 -1.4894 ES8 DepMap CRISPR Gene Dependency 1.0 3.06207 Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null SMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30763 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.880349 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3963 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34416 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_erythroblast_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SELENOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72902 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930743 STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67922 Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 5.97787 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.925696 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.2061 NCIH23 CCLE Cell Line Gene Expression Profiles 1.0 1.54378 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.57204 hsa-miR-877 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7886 L33 CCLE Cell Line Gene CNV Profiles 1.0 1.62886 Plasma membrane-derived chromatophore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.905 MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5593 ZFP57 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8228 ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5636 TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 69.7124 Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PL45 CCLE Cell Line Gene CNV Profiles 1.0 1.94643 LN215 CCLE Cell Line Gene Expression Profiles -1.0 -1.53701 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDST8 CCLE Cell Line Gene Expression Profiles 1.0 1.80004 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -0.111568 PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 SP1 ENCODE Transcription Factor Targets 1.0 null HCC1359 CCLE Cell Line Gene Expression Profiles 1.0 1.62446 vagina GTEx Tissue Gene Expression Profiles -1.0 -0.876681 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14824 hsa-miR-590-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05842 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.998539 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983272 hsa-miR-4739 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 TGFBR1_activemutant_291_GSE14523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.63934 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3626 Brain Lower Grade Glioma_LGG_TCGA-FG-8188-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCI15A DepMap CRISPR Gene Dependency 1.0 2.29605 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7101 PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2752 OSC19 DepMap CRISPR Gene Dependency 1.0 2.48995 tongueepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Nuclear exosome targeting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.774 MYOD1 ENCODE Transcription Factor Targets 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5841 BNC1_KD_GDS1978_70_mouse_oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.53787 SW156 COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10065 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.74868 Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5519 hsa-miR-520h TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K27me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF576 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06302 D542MG DepMap CRISPR Gene Dependency 1.0 3.1153 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARNT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66439 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0639 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.1709 hsa-miR-4708-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.88271 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LCLC97TM1 DepMap CRISPR Gene Dependency 1.0 2.46646 MOGGUVW DepMap CRISPR Gene Dependency 1.0 3.27831 NCIH2052 CCLE Cell Line Gene Expression Profiles 1.0 1.54866 PAX6 ChEA Transcription Factor Targets 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein complex GO Cellular Component Annotations 2015 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22567 hsa-miR-23c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.34272 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8192 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26716 JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.66441 COLO678 CCLE Cell Line Gene CNV Profiles 1.0 1.79064 NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -2.27446 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.457 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.4603 FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.2068 REST ENCODE Transcription Factor Targets 1.0 null GSE175787_5_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2325 H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CALU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61361 Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.1398 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.606 CTNNB1 ChEA Transcription Factor Targets 1.0 null NCIH2196 CCLE Cell Line Gene CNV Profiles -1.0 -1.44834 CTCF ENCODE Transcription Factor Targets 1.0 null PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9685 NCIH1563 CCLE Cell Line Gene CNV Profiles 1.0 2.33394 CORL88 CCLE Cell Line Gene Expression Profiles -1.0 -1.56959 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null NCIH810 CCLE Cell Line Gene CNV Profiles 1.0 1.37679 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7734 MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5909 HCC1187 DepMap CRISPR Gene Dependency 1.0 2.05442 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4956 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9935 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.809 intermediate filament GO Cellular Component Annotations 2015 1.0 null hsa-miR-3609 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953588 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868066 LS513 DepMap CRISPR Gene Dependency 1.0 2.8414 TEN CCLE Cell Line Gene CNV Profiles -1.0 -1.46955 KPNYS DepMap CRISPR Gene Dependency 1.0 2.11792 EC-GI-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE48812_0_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF219 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22365 AGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27043 SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS123 DepMap CRISPR Gene Dependency 1.0 3.00513 EM2 CCLE Cell Line Gene CNV Profiles 1.0 1.58254 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9094 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RF-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CMPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10269 hsa-miR-4430 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF415 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93936 BNC1_KD_GDS1978_738_mouse_Oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0078 ARH77 DepMap CRISPR Gene Dependency 1.0 2.03234 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.924 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null keratin filament GO Cellular Component Annotations 2015 1.0 null hsa-miR-4674 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2915 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8988 primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.83503 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null DOK DepMap CRISPR Gene Dependency 1.0 2.19326 hsa-miR-1253 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 CAPAN-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6378 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSF1_01_155 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.07673 primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.886227 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45527 Developmental Biology Reactome Pathways 2024 1.0 null THP1 DepMap CRISPR Gene Dependency 1.0 2.14726 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12921 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75384 VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7762 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -2.85584 Brain Lower Grade Glioma_LGG_TCGA-S9-A89Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4728-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 JUND_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOD2_KO_GDS1080_128_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.863008 TT1TKB DepMap CRISPR Gene Dependency 1.0 2.51059 HUTU80 CCLE Cell Line Gene Expression Profiles 1.0 1.45375 SLR23 CCLE Cell Line Gene Expression Profiles -1.0 -2.06356 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13902 CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null HT1197 CCLE Cell Line Gene Expression Profiles 1.0 1.70647 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6454 MLX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9544 496100448_TCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.32086 Keratinization Reactome Pathways 2024 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15546 IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 1.86008 POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04027 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5617 HS936T DepMap CRISPR Gene Dependency 1.0 2.92055 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6327 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -1.86612 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0576 ATAD3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47611 GSE217452_3_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null aging GO Biological Process Annotations 2015 1.0 null 496100563_PCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.41873 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09225 MOLT-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null 8MGBA DepMap CRISPR Gene Dependency 1.0 2.02141 DEL COSMIC Cell Line Gene Mutation Profiles 1.0 null SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.57134 GSE85880,GSE85881_4_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2528 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0078 GCT CCLE Cell Line Gene Expression Profiles 1.0 2.10033 Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.247 IHH-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null SOX5 JASPAR Predicted Transcription Factor Targets 1.0 null VMRCLCD CCLE Cell Line Gene Expression Profiles -1.0 -1.61044 GSE235605,GSE235701_0_v_1_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.656363 FOXO1_01_106 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.12756 PRDM1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9383 Autosomal dominant woolly hair DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.878 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8310-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0243 CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.536 hsa-miR-3652 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9406 SNU1077 DepMap CRISPR Gene Dependency 1.0 2.20932 posteroventral (inferior) parietal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45814 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6295 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IFT172 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78022 Scalp TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 KMH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE118548_1_v_0_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6827 NB5 COSMIC Cell Line Gene Mutation Profiles 1.0 null extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null Acrofacial dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.099 Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00391 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3915 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 JUND-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9269 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.598 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null LB771HNC DepMap CRISPR Gene Dependency 1.0 2.59477 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894209 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8635 EZH2 ENCODE Transcription Factor Targets 1.0 null 143B CCLE Cell Line Gene Expression Profiles 1.0 2.40948 Brain Lower Grade Glioma_LGG_TCGA-HT-7606-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.416 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3484 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4903 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.21947 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3185 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ZNF549 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7357 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7342 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15891 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8824 MDA-MB-175-VII COSMIC Cell Line Gene Mutation Profiles 1.0 null PRDM1 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5273 HCC2218 CCLE Cell Line Gene CNV Profiles -1.0 -1.92062 RMGI CCLE Cell Line Gene CNV Profiles 1.0 1.50314 NEUROD2-26341353-CORTEX-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LN319 CCLE Cell Line Gene Expression Profiles -1.0 -1.78885 GSE175787_8_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22414 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5956 Lipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6769 NCI-H28 COSMIC Cell Line Gene Mutation Profiles 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04145 Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36914 GSE245778_1_v_0_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4997 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57193 HD-MY-Z COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35503 MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.98416 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846934 Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.708 NO11 DepMap CRISPR Gene Dependency 1.0 2.80211 GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null TAL1 ENCODE Transcription Factor Targets 1.0 null FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.509 Angioblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.525 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.881765 HEYA8 CCLE Cell Line Gene Expression Profiles 1.0 1.69027 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1315 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3148 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4638 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7509 SKES1 CCLE Cell Line Gene CNV Profiles -1.0 -2.3685 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null SNU738 CCLE Cell Line Gene CNV Profiles -1.0 -1.32119 USF1 ENCODE Transcription Factor Targets 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.03733 ALX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60578 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB13 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29527 ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3322 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8369 OVCA420 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4711 hsa-miR-1321 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 12.7077 hsa-miR-3158-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.11712 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.933153 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.970597 Omegae TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.202 MSTO211H CCLE Cell Line Gene Expression Profiles 1.0 1.48463 Brain Lower Grade Glioma_LGG_TCGA-QH-A6X8-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNMC DepMap CRISPR Gene Dependency 1.0 2.00087 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24099 GSE233647_2_v_0_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null Hair follicle bulge stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.717 Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adipose tissue GTEx Tissue Gene Expression Profiles 1.0 1.17947 EN1 JASPAR Predicted Transcription Factor Targets 1.0 null 18614019-TableS4d GeneSigDB Published Gene Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.834531 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3219 SKOV3 DepMap CRISPR Gene Dependency 1.0 2.33386 TAF2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SP1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 697 DepMap CRISPR Gene Dependency 1.0 2.60119 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.725868 GSE48812_11_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TRAPP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.661 SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -2.17191 OVCAR8 CCLE Cell Line Gene Expression Profiles 1.0 1.4631 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38365 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.52884 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06881 cell part GO Cellular Component Annotations 2015 1.0 null OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967591 hsa-miR-4697-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null C3A CCLE Cell Line Gene Expression Profiles -1.0 -1.76314 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8905 T24 CCLE Cell Line Gene Expression Profiles 1.0 1.4449 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3175 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 B800-820 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.179 GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null NIHOVCAR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.52101 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30305 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null A-CA-04-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.43685 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.64952 BT474 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.927458 hsa-miR-632 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE239844_1_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2163 XKR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99473 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06003 MTRF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47325 H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46476 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19988 H2AFZ ENCODE Transcription Factor Targets 1.0 null MAX::MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2381 hsa-miR-330-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05195 Intestinal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.558 TC71 CCLE Cell Line Gene CNV Profiles -1.0 -1.58246 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKBR3 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 IALM CCLE Cell Line Gene Expression Profiles 1.0 2.12808 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3544 Weyers acrofacial dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.297 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.5848 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null SUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 2.1657 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0642 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9609 Ciliary rootlet COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.043 hsa-miR-3179 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ESR1_T47D_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919436 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03424 SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.738 hsa-miR-520g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9774 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.821728 PCI30 DepMap CRISPR Gene Dependency 1.0 3.01079 mpkCCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.11 EB2 COSMIC Cell Line Gene Mutation Profiles 1.0 null COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.35079 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87651 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.4115 PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Arrector pili muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5945 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.943 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9226 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00863 JHOM2B CCLE Cell Line Gene CNV Profiles -1.0 -1.70145 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972865 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6603 H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7699 Stratum granulosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.558 OE33 CCLE Cell Line Gene CNV Profiles -1.0 -1.35177 DK-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DM3 CCLE Cell Line Gene Expression Profiles 1.0 1.5586 QIMR-WIL COSMIC Cell Line Gene Mutation Profiles 1.0 null TP53BP1_KD_GSE54268_670_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30825 NFATC2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62147 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8682 NCI-H1915 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MDST8 COSMIC Cell Line Gene Mutation Profiles 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967591 LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8569 EGI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3894 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9967 FOS ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46D-01A-21R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1155 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTNNB1-20460455-HCT116-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H1092 COSMIC Cell Line Gene Mutation Profiles 1.0 null KPL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.35079 SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.808 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3108 PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null BECKER CCLE Cell Line Gene CNV Profiles -1.0 -2.82232 Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.767 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9684 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC-04-03 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism developmental process GO Biological Process Annotations 2015 1.0 null HCC1395 DepMap CRISPR Gene Dependency 1.0 2.71348 BLOC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.65 Angiolipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.984 COA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0397 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1885 POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFO21 CCLE Cell Line Gene Expression Profiles -1.0 -1.81367 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.876928 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6321 hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.59281 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1164 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925309 SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04246 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43305 AU565 CCLE Cell Line Gene CNV Profiles 1.0 2.13742 NCIH1299 CCLE Cell Line Gene CNV Profiles -1.0 -1.64065 BICR31 CCLE Cell Line Gene CNV Profiles 1.0 1.48396 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5702 HSF1 ChEA Transcription Factor Targets 1.0 null PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null NFE2L2_Mutation_GDS4498_597_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44086 multicellular organismal process GO Biological Process Annotations 2015 1.0 null HUH7 DepMap CRISPR Gene Dependency 1.0 2.85384 3-M syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.175 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-157 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA2_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9758 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8031 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.637506 FOXP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90057 hsa-miR-4419a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.682 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5825 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.41519 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21285 MDAMB436 DepMap CRISPR Gene Dependency 1.0 2.37532 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1894 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4815-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 8505C CCLE Cell Line Gene Expression Profiles 1.0 2.75666 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68402 D-247MG COSMIC Cell Line Gene Mutation Profiles 1.0 null LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2177 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.54087 JHU029 DepMap CRISPR Gene Dependency 1.0 2.94994 KYAE-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 GSE206729_5_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0365 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.08542 ZNF140 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33707 SF1_01_271 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.0065 PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0 MYOD1_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.894554 HUP-T3 COSMIC Cell Line Gene Mutation Profiles 1.0 null TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4598 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4406 hsa-miR-4273 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8608 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4423 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9598 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2619 SP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07507 Scapula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.154 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.826105 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.970961 UMRC7 DepMap CRISPR Gene Dependency 1.0 2.13929 A673 CCLE Cell Line Gene Expression Profiles 1.0 1.40746 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW948 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.871582 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1419 CCLE Cell Line Gene CNV Profiles -1.0 -1.49595 CSDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57874 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4437 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.38034 PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4XB-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VCB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.731 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.07611 Esophageal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.776 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24958 ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.141 NUGC4 CCLE Cell Line Gene CNV Profiles 1.0 1.95068 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2412 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.12334 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6852 SF295 COSMIC Cell Line Gene Mutation Profiles 1.0 null HAL-01 COSMIC Cell Line Gene Mutation Profiles 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.9565 C12orf57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66389 CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0854 COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66004 ventrolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.45603 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN-26020271-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 1.0 3.92179 PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null FOSL1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.615 TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7727 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864966 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4598 intracellular part GO Cellular Component Annotations 2015 1.0 null REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gata-4_KO_GDS4782_329_mouse_Adult heart during pressure overload GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08906 Papilloma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.189 MYC ChEA Transcription Factor Targets 1.0 null Keratin-associated protein InterPro Predicted Protein Domain Annotations 1.0 null TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.92948 hsa-miR-23b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3891 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7676 HOXD11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1045 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7091 ACSS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2007 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4756-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06082 ZNF554 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89233 PANC1005 CCLE Cell Line Gene CNV Profiles 1.0 1.85742 GATA2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHESOAD1 CCLE Cell Line Gene CNV Profiles 1.0 1.75621 GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null JHH-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24253 molting cycle GO Biological Process Annotations 2015 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.939515 Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9457 MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66784 mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15891 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83769 CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.59019 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29527 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7028 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5116 primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.52518 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925995 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4141 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3553 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6986 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30508 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20823 H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GADD45GIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35177 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCF-STTG1 COSMIC Cell Line Gene Mutation Profiles 1.0 null USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7766 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE175787_4_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Cytoplasmic ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.7 BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9608 GID complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.838 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -1.76869 FOSL1 ENCODE Transcription Factor Targets 1.0 null MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.68434 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4656 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 1.74409 SKHEP1 CCLE Cell Line Gene Expression Profiles 1.0 1.37049 20140255-TableS2 GeneSigDB Published Gene Signatures 1.0 null TRIM52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00067 hsa-miR-3681 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 NCIH1915 CCLE Cell Line Gene CNV Profiles -1.0 -1.80157 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.92279 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7252 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97789 NCI-H841 COSMIC Cell Line Gene Mutation Profiles 1.0 null YD15 DepMap CRISPR Gene Dependency 1.0 2.11618 GCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62131 JUND-26020271-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null A2780 COSMIC Cell Line Gene Mutation Profiles 1.0 null TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8063 MSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07834 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.2454 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87855 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.223 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.28202 15735024-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.927 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.856145 STAT1_01_21 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.1525 AM38 CCLE Cell Line Gene Expression Profiles 1.0 1.97383 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34466 3M complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.397 FOS_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MLXIPL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6075 ES2 CCLE Cell Line Gene Expression Profiles 1.0 2.18373 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.694352 MYOG ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09551 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28727 HCC1171 CCLE Cell Line Gene CNV Profiles 1.0 1.44751 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4598