association dataset threshold value standardized value NCIH650 DepMap CRISPR Gene Dependency 1.0 4.21031 Hair shaft TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.891 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32692 cytoskeletal part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Hair root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.677 paracentral lobule, posterior part, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.944375 SPI1 ChEA Transcription Factor Targets 1.0 null HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 2.66854 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.943516 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33015 TALL1 CCLE Cell Line Gene CNV Profiles 1.0 2.86789 DM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.79771 DBTRG05MG CCLE Cell Line Gene CNV Profiles 1.0 1.81838 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0937 FAHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00272 intermediate filament COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.5931 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18565 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.869374 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172735 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040678 ZR751 CCLE Cell Line Gene CNV Profiles -1.0 -1.37637 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null pyramidal cells of caudal CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03778 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.61092 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-593 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.9559 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null IALM CCLE Cell Line Gene Expression Profiles -1.0 -1.52262 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.896538 PANC1 CCLE Cell Line Gene Expression Profiles 1.0 1.42065 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23548 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06645 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.84364 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851117 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.89497 ZNF275 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89632 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.8515 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4346-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07319 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.885344 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06719 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.7205 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.5435 immune system phenotype IMPC Knockout Mouse Phenotypes 1.0 null basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874267 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24612 increased lung elastance MGI Mouse Phenotype Associations 2023 1.0 null Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41703 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31247 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2349 Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1710 CCLE Cell Line Gene Expression Profiles -1.0 -1.81581 Perturb_18394_KO_Ivl_SRP286259 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.0459 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3112 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.112 Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29016 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11633 sw13 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.199 SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.722105 MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null spectrin-associated cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.459 ovary HPA Tissue Protein Expression Profiles -1.0 -2.54835 CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.37024 NTERA2CLD1 DepMap CRISPR Gene Dependency 1.0 2.13268 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.3962 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.0263 RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3808 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34105 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955944 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17661 MESSA CCLE Cell Line Gene Expression Profiles 1.0 1.38113 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32212 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.86151 NCIH1694 CCLE Cell Line Gene CNV Profiles 1.0 2.04183 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955028 intermediate filament GO Cellular Component Annotations 2015 1.0 null hsa-miR-4329 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.51585 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.998425 Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.697 orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64811 KYO1 CCLE Cell Line Gene CNV Profiles 1.0 1.61065 precentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.884302 NCIH1373 DepMap CRISPR Gene Dependency 1.0 6.65661 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33418 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00667 Dhori Virus_12Hour_20090954_GSE17400 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.61689 SULT1C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02975 hsa-miR-562 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 decreased T-helper cell number IMPC Knockout Mouse Phenotypes 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null TRIO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88726 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.01246 Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00778 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961684 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.975946 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0513 Bronchus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4671 KYSE270 DepMap CRISPR Gene Dependency 1.0 6.60379 KLE CCLE Cell Line Gene CNV Profiles 1.0 1.33215 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.93912 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -2.89755 GR MotifMap Predicted Transcription Factor Targets 1.0 null PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null F5 DepMap CRISPR Gene Dependency 1.0 3.7741 abnormal heart morphology IMPC Knockout Mouse Phenotypes 1.0 null Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.037752 Hair root TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MEAK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67826 ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1031 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.58158 JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -1.95271 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01245 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.86949 skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44335 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858225 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.87703 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871656 PBX1 ChEA Transcription Factor Targets 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83664 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047982 rostral group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.977345 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.87124 ZNF189 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3903 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6667 NCCSTCK140 CCLE Cell Line Gene Expression Profiles -1.0 -1.69685 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inflorescence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461465 thyroid gland HPA Tissue Protein Expression Profiles 1.0 0.939278 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09288 NCIH3255 CCLE Cell Line Gene Expression Profiles -1.0 -1.97814 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2897 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6265 NKX2-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.954 bronchus HPA Tissue Protein Expression Profiles 1.0 0.939278 Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.1023 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885409 decreased body weight MGI Mouse Phenotype Associations 2023 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.828955 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0673 decreased T-helper cell number MGI Mouse Phenotype Associations 2023 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-8118-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ovary GTEx Tissue Gene Expression Profiles -1.0 -1.17497 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37818 3M complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.229 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.9265 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.990217 CHLA90 DepMap CRISPR Gene Dependency 1.0 8.08324 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.10186 organelle part GO Cellular Component Annotations 2015 1.0 null stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.612958 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824034 hsa-miR-3978 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 RCM1 DepMap CRISPR Gene Dependency 1.0 3.94439 primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37773 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10905 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6567 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9761 arrangement GeneRIF Biological Term Annotations 1.0 null primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90211 TE14 CCLE Cell Line Gene CNV Profiles -1.0 -1.33147 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4983 NPHP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.508 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.5791 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.889138 A704 CCLE Cell Line Gene Expression Profiles 1.0 1.40661 Uterus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.089 Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51855 hsa-miR-3689c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4975-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HES6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33827 regulated GeneRIF Biological Term Annotations 1.0 null GSE220813_0_v_1_zfp750_mouse RummaGEO Gene Perturbation Signatures -1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.834502 hsa-miR-3169 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 decreased CD4-positive, alpha-beta T cell number IMPC Knockout Mouse Phenotypes 1.0 null DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35512 Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5666 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.22969 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OU-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59745 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.89408 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.86613 flower TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.466111 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34909 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.981629 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30667 HUPT4 DepMap CRISPR Gene Dependency 1.0 2.01981 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.078 OVMANA CCLE Cell Line Gene Expression Profiles 1.0 2.65454 lordosis MGI Mouse Phenotype Associations 2023 1.0 null NCIH23 DepMap CRISPR Gene Dependency 1.0 2.1257 EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.1833 CMK115 CCLE Cell Line Gene CNV Profiles 1.0 2.22526 enlarged heart IMPC Knockout Mouse Phenotypes 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6114 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66132 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.12655 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4318 estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phycobiont TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.623043 hsa-miR-331-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SNU387 CCLE Cell Line Gene CNV Profiles -1.0 -1.78738 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.833515 Serotonergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.533 ZR-75-30 COSMIC Cell Line Gene CNV Profiles -1.0 -5.12655 Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null etanercept_homo sapiens_gpl570_gse41663 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.898328 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8463 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41818 Sarcoma_SARC_TCGA-IE-A4EI-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX2-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU324 CCLE Cell Line Gene CNV Profiles -1.0 -2.15812 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.3476 ES5 DepMap CRISPR Gene Dependency 1.0 2.8326 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null immune system phenotype MGI Mouse Phenotype Associations 2023 1.0 null LPS6 DepMap CRISPR Gene Dependency 1.0 3.21096 Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.67909 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914799 ZR7530 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 GATA3-21878914-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100660_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.60336 Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LASV_FML29_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.82068 SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Plant collar TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.58 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00141 HDAC1 ENCODE Transcription Factor Targets 1.0 null OC314 DepMap CRISPR Gene Dependency 1.0 3.81269 Epilepsy DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 BHLHE40_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal heart morphology MGI Mouse Phenotype Associations 2023 1.0 null PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49272 SH3PXD2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45031 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null enlarged heart MGI Mouse Phenotype Associations 2023 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01473 CORL311 CCLE Cell Line Gene Expression Profiles 1.0 1.58246 EW8 DepMap CRISPR Gene Dependency 1.0 2.40333 JURKAT DepMap CRISPR Gene Dependency 1.0 8.2103 Hypotrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.431 Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8634 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K9me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.254 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12093 precuneus, left, superior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.958636 Vitamin D receptor pathway WikiPathways Pathways 2024 1.0 null Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Pancreas BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.0585 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54743 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79688 A2058 CCLE Cell Line Gene Expression Profiles -1.0 -2.36568 TRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49529 hsa-miR-4519 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC2218 CCLE Cell Line Gene Expression Profiles 1.0 1.69578 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08011 superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.835819 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04883 WM3772F DepMap CRISPR Gene Dependency 1.0 3.24507 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.57923 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47917 GSE181513_2_v_1_usp7_human RummaGEO Gene Perturbation Signatures 1.0 null ETV6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3005 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5578 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.9362 TCF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81716 NCO2 DepMap CRISPR Gene Dependency 1.0 3.19091 Scalp TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.92805 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72295 ETS1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29418 cellular_component GO Cellular Component Annotations 2015 1.0 null YY1AP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11286 increased lung elastance IMPC Knockout Mouse Phenotypes 1.0 null Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.899185 Hypertrichosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.28 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.5797 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hair follicle outer root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.392 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042216 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14385 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SCAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24783 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24612 TMEM190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31277 Adenocarcinoma DisGeNET Gene-Disease Associations 1.0 null 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26007 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.085 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 496100396_HIP_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07587 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06719 Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8896 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04903 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11018 Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.8625 Sarcoma_SARC_TCGA-DX-A6YT-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.984517 ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.24986 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0342 chromosomal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044073 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851862 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5189-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885409 Toe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.864 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4174 spleen HPA Tissue Protein Expression Profiles -1.0 -1.00077 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13904 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.06898 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55123 Arrector pili muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.607 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7948 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33402 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34197 SCC25 DepMap CRISPR Gene Dependency 1.0 4.57914 U118MG CCLE Cell Line Gene Expression Profiles -1.0 -1.98578 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042253 Monilethrix DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.681 cell part LOCATE Predicted Protein Localization Annotations 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903791 yy2_20215434_hela_lof_human_gpl570_gds3788 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.05056 PCYOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37162 Alopecia areata DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 mpkCCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.873 Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11947 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1117 Hair follicle development cytodifferentiation stage 3 of 3 WikiPathways Pathways 2024 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4999-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skin GTEx Tissue Gene Expression Profiles 1.0 2.18987 primary motor cortex (area M1, area 4)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.873808 parathyroid gland HPA Tissue Protein Expression Profiles 1.0 0.939278 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852639 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961684 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.67474 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.533 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870565 reticular nucleus of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25552 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.56819 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KYM1 DepMap CRISPR Gene Dependency 1.0 5.83446 Lung TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100490_HIP_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.80606 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0266 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79261 Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3689a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.85819 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.61383 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955944 Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3529 Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -2.15355 dorsolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3322 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0137 JAG1_OE_GDS3571_40_human_endometrial stromal cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null small intestine GTEx Tissue Gene Expression Profiles -1.0 -1.17497 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hydrometra MGI Mouse Phenotype Associations 2023 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1555 Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15081 NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 1.68075 Sarcoma_SARC_TCGA-VT-A80G-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 0.939278 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96869 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.24764 H3K9me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07264 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11633 Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.822561 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7062-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Degenerative myopia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43668 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08601 H2AFZ ENCODE Transcription Factor Targets 1.0 null KPNA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34635 fallopian tube HPA Tissue Protein Expression Profiles 1.0 0.939278 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.997117 LS123 DepMap CRISPR Gene Dependency 1.0 2.02562 Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37818 Cockayne syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.073 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11066 Hair TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.662 GSE133070_2_v_4_prss1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3151 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042991 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.51815 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16239 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886411 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.17497 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97994 MRS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62029 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -1.94127 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Claw TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.987 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -3.47148 CCNB1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32531 chromosome, centromeric region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196999 ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7748 SERPINH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70129 NCIH2126 DepMap CRISPR Gene Dependency 1.0 2.3362 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.27837 Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCIH2110 CCLE Cell Line Gene CNV Profiles -1.0 -1.91966 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886411 Gut microbiota (bacterial taxa, hurdle binary method) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 DBTRG05MG CCLE Cell Line Gene Expression Profiles -1.0 -1.47087 Lassa Fever Virus_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.8849 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 hippocampus (hippocampal formation)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91847 SK-MEL-31 COSMIC Cell Line Gene Mutation Profiles 1.0 null Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55154 Scapula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.218 Rumen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.813 496100346_FWM_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.76705 posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.93707 Cloned cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.515 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1265 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2787 cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1741 primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13547 Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCIH1105 CCLE Cell Line Gene Expression Profiles -1.0 -1.50925 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular organelle part GO Cellular Component Annotations 2015 1.0 null HCC366 CCLE Cell Line Gene CNV Profiles -1.0 -2.50189 GSE146045_1_v_0_lama3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54168 Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.18476 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.959074 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null CPEB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67631 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.795531 NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.931201 TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.94966 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100349_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.97667 Hair TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL5 DepMap CRISPR Gene Dependency 1.0 2.51288 ATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2135 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -1.74259 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.900429 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.924 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20413 VKORC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69721 SG231 DepMap CRISPR Gene Dependency 1.0 2.85147 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20121 HS839T CCLE Cell Line Gene Expression Profiles 1.0 1.3697 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00852 TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4143 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.985217 SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SNU175 CCLE Cell Line Gene Expression Profiles 1.0 1.35299 SAMD4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59913 cell part GO Cellular Component Annotations 2015 1.0 null RMUGS CCLE Cell Line Gene CNV Profiles -1.0 -1.35906 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42645 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825016 Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.038 KM12 CCLE Cell Line Gene CNV Profiles -1.0 -1.71717 CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC15A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22544 PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.55571 Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.8081 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57087 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.2289 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.866824 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.998425 PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.34523 TSFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29092 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04921 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebrooculofacioskeletal syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.813 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.4949 fiber GeneRIF Biological Term Annotations 1.0 null NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28904 Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.5618 SUPHD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.88403 ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50502 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00778 Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5893 HSC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.44602 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.900434 LCAM1 DepMap CRISPR Gene Dependency 1.0 2.03158 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930145 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00852 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10905 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.3288 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.621 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC102A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49627 SNU81 CCLE Cell Line Gene Expression Profiles -1.0 -1.50372 POLR2A ENCODE Transcription Factor Targets 1.0 null 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.35666 RMI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28648 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.751 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.157039 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77584 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.7553 Hair disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.64 Respiratory system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.036 Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.882816 PLCPRF5 CCLE Cell Line Gene CNV Profiles 1.0 1.40519 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3428 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.93087 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961684 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.450438 GIMEN DepMap CRISPR Gene Dependency 1.0 5.99674 Ectodermal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.11 BHLHE40 ENCODE Transcription Factor Targets 1.0 null dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.89536 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.279612 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1982 hydrometra IMPC Knockout Mouse Phenotypes 1.0 null Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.8035 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9789 HOXB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68515 WERIRB1 DepMap CRISPR Gene Dependency 1.0 2.11968 POTEI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90059 COLO680N CCLE Cell Line Gene Expression Profiles -1.0 -1.51183 Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.900434 intracellular part GO Cellular Component Annotations 2015 1.0 null dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34075 KYSE180 CCLE Cell Line Gene Expression Profiles 1.0 1.97975 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955944 callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.86144 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32544 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26247 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNB75 CCLE Cell Line Gene CNV Profiles 1.0 1.33048 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A4TM-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hair root TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intermediate filament cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.45004 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13817 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.37769 HDMYZ DepMap CRISPR Gene Dependency 1.0 6.61331 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.55756 Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRMT2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.93359 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824034 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.614571 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0494 496100567_PCx_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.71845 GLTP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35659 GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.76482 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31068 Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868972 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.84204 PANC0203 CCLE Cell Line Gene Expression Profiles 1.0 1.43649 HS888T CCLE Cell Line Gene Expression Profiles -1.0 -2.15339 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 OVTOKO CCLE Cell Line Gene Expression Profiles 1.0 2.32962 plant form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.301398 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31326 substantia innominata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.98299 epidermis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914034 FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9939 SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851862 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865592 inner SZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845454 hair GeneRIF Biological Term Annotations 1.0 null Rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.64094 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01245 Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2174 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4975 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20866 TT CCLE Cell Line Gene CNV Profiles -1.0 -1.55121 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.10115 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null Atoh1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.008 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77584 Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04646 VMRCLCD CCLE Cell Line Gene CNV Profiles -1.0 -1.79968 JURKAT CCLE Cell Line Gene Expression Profiles -1.0 -2.39688 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.3346 central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23105 K562 CCLE Cell Line Gene Expression Profiles 1.0 2.14617 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75672 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epidermis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 primary auditory cortex (core)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08505 hsa-miR-4461 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 RNF2-27304074-CHIP-SEQ-NSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Gut microbiota (bacterial taxa) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.922185 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7919-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13817 Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZKSCAN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9241 Alopecia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.378 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5563 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOGGCCM CCLE Cell Line Gene CNV Profiles 1.0 1.33548 DOV13 CCLE Cell Line Gene CNV Profiles 1.0 1.51975 ECC4 DepMap CRISPR Gene Dependency 1.0 2.58148 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.158315 precuneus, left, inferior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05955 PATU8902 CCLE Cell Line Gene CNV Profiles -1.0 -1.65286 Brain disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 NCI-H211 COSMIC Cell Line Gene Mutation Profiles 1.0 null NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CHSA8926 COSMIC Cell Line Gene Mutation Profiles 1.0 null A-Vietnam-1203-2004(H5N1)_24Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.22751 Cardiac muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36452 protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07141 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01545 SCH DepMap CRISPR Gene Dependency 1.0 5.30199 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.666 KNS62 CCLE Cell Line Gene Expression Profiles 1.0 2.0124 SNU1076 CCLE Cell Line Gene CNV Profiles -1.0 -1.79525 hsa-miR-513b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 253J DepMap CRISPR Gene Dependency 1.0 2.62005 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12036 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.49105 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20121 ventrolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825016 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47728 filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.623043 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35651 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4951 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51363 decreased body weight IMPC Knockout Mouse Phenotypes 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25541 SIRT6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null yy1_20215434_hela_lof_human_gpl570_gds3788 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.058017 HDAC2 ENCODE Transcription Factor Targets 1.0 null 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.86348 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37066 RT11284 CCLE Cell Line Gene CNV Profiles 1.0 1.39515 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987207 HSC2 CCLE Cell Line Gene Expression Profiles 1.0 1.42023 hsa-miR-1224-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.149 decreased CD4-positive, alpha-beta T cell number MGI Mouse Phenotype Associations 2023 1.0 null KMS18 CCLE Cell Line Gene Expression Profiles -1.0 -1.58283 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21937 small intestine HPA Tissue Protein Expression Profiles 1.0 0.939278 JHUEM1 DepMap CRISPR Gene Dependency 1.0 2.22289 MARK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4655 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Cuticle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0535 PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50307 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.849173 macromolecular complex GO Cellular Component Annotations 2015 1.0 null dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00428 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040565 hsa-miR-4653-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 SET2 CCLE Cell Line Gene CNV Profiles 1.0 2.01729 Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adipose tissue GTEx Tissue Gene Expression Profiles 1.0 1.20379 Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.665 GSE142684_4_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null NR5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42502 hair TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null 496100536_HIP_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.11552 U2OS CCLE Cell Line Gene CNV Profiles 1.0 1.42892 breast HPA Tissue Protein Expression Profiles -1.0 -0.738022 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43024 Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZKSCAN5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.908 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EE-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34409 Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1066 CCLE Cell Line Gene Expression Profiles 1.0 1.35996 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.887217 Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.049 WRAP73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49276 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.919169 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.939843 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36436 PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3 Rummagene Transcription Factor Associations 2026 1.0 null Keratinization Reactome Pathways 2024 1.0 null NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 scalp TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40663 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5611 Hair follicle inner root sheath TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.486 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7686 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04473 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypothalamus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.52524 intermediate GeneRIF Biological Term Annotations 1.0 null occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860267 side GeneRIF Biological Term Annotations 1.0 null NDUFAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7873 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.51217 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.14329 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.172735 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09695 GSE149880_2_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.8808 TTC549 DepMap CRISPR Gene Dependency 1.0 2.39342 RNPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.587 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3369 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18193 Vermiform appendix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr21_30812633_A_C_b38 GTEx eQTL 2025 1.0 1.1165 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01245 NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955028 RNF227 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92939 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5234 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.700728 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1982 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null helical GeneRIF Biological Term Annotations 1.0 null cisplatin_mus musculus_gpl339_gds3099 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GT-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3665 Lung adenocarcinoma_LUAD_TCGA-91-7771-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUHR10TKB CCLE Cell Line Gene CNV Profiles 1.0 1.57683 inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10659 WNT_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33951 MM253 DepMap CRISPR Gene Dependency 1.0 2.88524 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.779 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.10632 Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 inferior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2118 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.24461 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDC42SE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61871 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7054 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.77018 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6526 filament GeneRIF Biological Term Annotations 1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 0.939278 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 OGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61361 digits BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.892756 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38021 Hair follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.748 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.851266 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.654212 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-FX-A3RE-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08324 PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10905 protein binding GO Molecular Function Annotations 2015 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 0.939278 Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF660 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34856 protein complex GO Cellular Component Annotations 2015 1.0 null Otopalatodigital syndrome spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.642 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.71144 Ileocecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59505 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3026 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00852 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969185 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100625_FWM_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.17121 NCI-H1792 COSMIC Cell Line Gene Mutation Profiles 1.0 null KD DepMap CRISPR Gene Dependency 1.0 2.91188 Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.8755 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54743 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052762 ERG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23452 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03215 Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6601 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20756 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933791 intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GP5D DepMap CRISPR Gene Dependency 1.0 2.69056 Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-89-LEF1_LEF1 Rummagene Transcription Factor Associations 2026 1.0 null ACOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07038 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873942 Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65168 hsa-miR-3921 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.939278 NDRG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_4485_OE_Mir29a/Mir29b1_SRP220351 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.19389 EGR3_01_34 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.5869 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.864001 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47728 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19542 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.89877 Idiopathic generalized epilepsy DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9106 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.253291 FADU CCLE Cell Line Gene CNV Profiles -1.0 -1.33063 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9599 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20026 COV504 CCLE Cell Line Gene CNV Profiles -1.0 -1.38383 TIE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26126 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28779 Six3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.671 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Corneocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 METTL21EP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6985 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4381 PL45 CCLE Cell Line Gene CNV Profiles -1.0 -1.38324 anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.848126 HEL CCLE Cell Line Gene CNV Profiles 1.0 2.20849 HS870T CCLE Cell Line Gene Expression Profiles 1.0 1.69939 CAL12T CCLE Cell Line Gene CNV Profiles 1.0 1.54482 BICR56 CCLE Cell Line Gene Expression Profiles 1.0 3.40424 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.990413 Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.0464 amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02616 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null QPCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41321 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886411 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37818 abnormal uterus morphology IMPC Knockout Mouse Phenotypes 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6165 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32939 HS618T CCLE Cell Line Gene Expression Profiles -1.0 -1.65442 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4163 lordosis IMPC Knockout Mouse Phenotypes 1.0 null Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate filament cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00344 Keratin-associated protein, type6/8/16/19/20 InterPro Predicted Protein Domain Annotations 1.0 null oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38984 MHHCALL2 CCLE Cell Line Gene CNV Profiles 1.0 1.68725 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95159 MHH-PREB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67878 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20121 SOX2_Deficiency_GDS4853_319_human_AZ-521 gastric cancer (GC) cell line - 8 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null U266B1 CCLE Cell Line Gene Expression Profiles 1.0 1.94596 FOXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18441 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.38689 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94525 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19072 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.993397 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null METTL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44323 Hoxa11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4389 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39463 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91574 CMK CCLE Cell Line Gene CNV Profiles 1.0 1.87475 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.23347 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91903 SOX11-22085726-ESNS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null stratum pyramidale of caudal CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950548 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.51815 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.332 TRMT44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73387 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01341 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11366 convex GeneRIF Biological Term Annotations 1.0 null PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9317 SMAD4-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 binding GO Molecular Function Annotations 2015 1.0 null HINFP JASPAR Predicted Transcription Factor Targets 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96869 outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929666 Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51453 ESPNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42107 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3331-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6962 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869562 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLOC-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.582 H3K9me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.860335 Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.714 molecular_function GO Molecular Function Annotations 2015 1.0 null MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.788333 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2106 CCLE Cell Line Gene CNV Profiles 1.0 1.70147 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.57 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72223 Bronchoalveolar system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 496100324_FWM_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.52337 planum temporale, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.946439 496100402_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14469 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior frontal gyrus, opercular part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.979191 NRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11476 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8052 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.816989 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.19193 VCAP CCLE Cell Line Gene CNV Profiles 1.0 1.70862 not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.965468 SU-DHL-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7924 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.926187 Heart TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abnormal uterus morphology MGI Mouse Phenotype Associations 2023 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.81103 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96869 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935583 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15477 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.513 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02144 COLO320 CCLE Cell Line Gene CNV Profiles -1.0 -2.31741 15793299-TableA GeneSigDB Published Gene Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6371-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null distributed GeneRIF Biological Term Annotations 1.0 null cytoskeletal part GO Cellular Component Annotations 2015 1.0 null Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLNRD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28686 Dermal papilla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.216 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null GSE63857_3_v_2_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8715 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50487 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05105 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.879534 Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25933 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21354 GID complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.671 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26827 heart muscle HPA Tissue Protein Expression Profiles 1.0 0.939278 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914034 KIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24426 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5092-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24293 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.23462 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03988 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RT112 CCLE Cell Line Gene CNV Profiles 1.0 1.73958 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.807299 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3085 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84818 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6356 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824034 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67878 Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7129-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rumen epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.578 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06813 MAPK8IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01134 FOXA1-21572438-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased startle reflex MGI Mouse Phenotype Associations 2023 1.0 null SH3BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59085 pyramidal cells of rostral CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09206 MC116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42482 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06719 inferior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.824719 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16358 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3418 H3K9me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8025 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3251 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.96 endometrium HPA Tissue Protein Expression Profiles -1.0 -1.00077 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased startle reflex IMPC Knockout Mouse Phenotypes 1.0 null rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27794 IGR1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33923 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K9ac_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.57051 epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 Developmental Biology Reactome Pathways 2024 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.92263 MEIOSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97133 B800-820 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.59 Perturb_18393_KO_923large_SRP286259 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.2155 LASV_FML29_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.90954 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94644 Cecum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KP1N DepMap CRISPR Gene Dependency 1.0 6.82459 chromosomal region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.089466 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00022 IGROV1 DepMap CRISPR Gene Dependency 1.0 2.74388 HEC1B DepMap CRISPR Gene Dependency 1.0 2.31872 Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.531 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2897 caudal subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.979312 CW9019 DepMap CRISPR Gene Dependency 1.0 2.55746 Uterine cervix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.78726 PL4 DepMap CRISPR Gene Dependency 1.0 5.99388 oral mucosa HPA Tissue Protein Expression Profiles -1.0 -1.00077 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.96869 hsa-miR-4283 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.87704 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0225 CDX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0039 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.42078 22RV1 DepMap CRISPR Gene Dependency 1.0 5.69104 Perturb_1295_KO_Trp53_SRP298760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.67317 SLC25A44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10241 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.81821 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.63247 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15307 subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913935 Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7203 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06263 uniquely GeneRIF Biological Term Annotations 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.41958 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33422 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.2134 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.14272 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00636 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.863897 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.23795 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838388 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.8339 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.705 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.6545 cisplatin_mus musculus_gpl339_gse6206 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Sarcoma_SARC_TCGA-X6-A7WC-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryoday9.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.955165 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null LASV_FML29 _4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.3675 LEF1-29337183-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null CFL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35467 Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null External side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.572 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00818 PLEKHA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 SNU719 CCLE Cell Line Gene Expression Profiles -1.0 -2.11969