association	dataset	threshold value	standardized value
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3894
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04396
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11622
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32482
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13122
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93949
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03312
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37748
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65675
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31387
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44909
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28497
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60282
GSE128688_0_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19793
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42378
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62801
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5114
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24168
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1083
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00731
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05076
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.334
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Supplementary_Table_14_Overlapping_DEG_list_from_CWR22Rv1-AR-EK_cells_depleted_of_AR-V7_and_treated_with_DNA-PK_inhibitor_NU5455_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26932
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60978
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90931
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2439
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17549
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01001
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15656
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36343
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34292
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248634_1_v_0_gnas_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101467_0_v_1_dock8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03574
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.544
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6498
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75971
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98288
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10877
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13136
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24367
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
chr17_38981046_C_T_b38	GTEx eQTL 2025	1.0	1.22153
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04945
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38921
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2569
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Glioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65962
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2524
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01679
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
DCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50639
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75892
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3815
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32108
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7446
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45547
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1957
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01302
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Minodronic acid_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0161752
chr17_38922627_C_T_b38	GTEx eQTL 2025	1.0	1.03294
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74179
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72704
GSE216043_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7383
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4571
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0585
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3623
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6422
Selinexor _BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0170457
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9411
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37791
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0223
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4531
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31905
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27296
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09825
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84187
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96841
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50068
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
Vismodegib_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00873275
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1853
ZNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44107
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8295
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HJURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36644
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7357
BRDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01955
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5536
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.06194
GSE238005_2_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14607
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10727
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44398
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12667
SLC25A29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24797
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09922
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55011
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02754
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-x_TFEB_KO_con_VS_WT_con_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22921
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73152
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-fromNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35207
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-251MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00182
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0224
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42358
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3894
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46929
ECPAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11019
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34192
chr17_38919253_G_A_b38	GTEx eQTL 2025	1.0	1.1859
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01125
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34241
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0228
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40529
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71781
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4177
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58672
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31384
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5462
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04316
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36824
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23425
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21792
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01811
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.153
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.25
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09859
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8683
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17254
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33149
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3116
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3534
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20178
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13601
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.752
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
EPHA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07419
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15184
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05754
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7229
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00788
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46896
ARID4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01746
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07474
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42739
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3764
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04613
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4589
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19729
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04284
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36552
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14197
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07946
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01041
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9623
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0637
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216274,GSE216292_4_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7941
PMC10061014-Table7.XLSX-C_vs_L-Table_S7a_Predicted_upstream_regulators_of_genes_showing_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4936
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60037
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04749
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41643
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8952
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
TLE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11227
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_NOT_Autophagy_NOT_GSE22255_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48899
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07682
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17638
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35365
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39725
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00812
GSE182680,GSE182683_10_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3184
SOX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.035
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58019
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67352
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59502
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31888
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21093
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38177
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5106
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61453
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00202
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52291
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88402
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28593
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.861
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03668
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S18-Table_S18_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-002_4H_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51505
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64942
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25606
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
PMC7927818-AAC.01755-20-s0002.xlsx-Supplemental_Table_1-Supplemental_Table_1_List_of_significantly_altered_genes_in_MDMs_differentiated_in_the_presence_of_PrEP_FTC_v_No_Drug_TDF_v_No_Drug_FTC_v_TDF_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8332
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35156
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42017
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ULK-101_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.00930501
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8756
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1098
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37029
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.88282
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46382
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5677
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51508
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39681
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09849
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220942_2_v_1_galnt7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8390644-41467_2021_25107_MOESM6_ESM.xlsx-Primed_BRG1-KD_significant-gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85537