association	dataset	threshold value	standardized value
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
Overactive bladder syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Perturb_1698_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.36264
Perturb_328_KD_GDF15_SRP201220	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65749
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.825
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15216
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4544
ANXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38179
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6874
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5021
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1628
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45564
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6822
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.6426
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34159
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YANK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2838
GFPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44816
SEC23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64148
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver cirrhosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PNPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14675
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary biliary cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1665
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.821
Interstitial cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8847
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
CCNB1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32531
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.1816
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C17orf107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27304
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0023
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.3561
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6586
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
NSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65129
ZNF699	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45142
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03952
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.2141
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
Perturb_14983_KO_Hdac2_SRP097585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0049
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125211_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.6116
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.5303
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62219
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1501
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.4067
GSE232786_1_v_0_otud1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92675
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.768
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
RETREG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75341
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9761
Steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51252
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
LMTK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63914
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99921
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78783
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
SMARCAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66854
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0
Eiii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6489
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3736
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23298
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2349
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22685
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr14_103075845_A_G_b38	GTEx eQTL 2025	1.0	1.23063
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3324
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr14_103081739_G_GAACAAACA_b38	GTEx eQTL 2025	1.0	1.93925
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3855
GSE149010_0_v_4_dars2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80187
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15007_KO_Hdac2_SRP097585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.2052
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78559
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	195.494
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.618
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6199
EPHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40773
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
Perturb_1436_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54556
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8184
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6592
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9974
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93918_1_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07486
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr14_103073762_A_G_b38	GTEx eQTL 2025	1.0	1.45333
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2833
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.0046
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.418
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83248
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.949
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stuttering	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.034
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.306
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1118
PHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82433
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65792
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07314
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1478
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45916
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1353
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41357
Nde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
GSE223334_3_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.437
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72965
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71516
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73815
GSE93918_1_v_0_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103124_2_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.303
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
GSE239578_1_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr14_103074759_G_C_b38	GTEx eQTL 2025	1.0	1.5089
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84921
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3358
GSE244710_1_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68379
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4275
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14817
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3125
GSE120595_0_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.181
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17355
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.378
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93918_2_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239578_2_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.301
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42096
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3975
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0989
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.843
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9142
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
Perturb_11460_KO_Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25536
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1041
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31701
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66715
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
Internal plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8488
HNRNPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69445
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5287
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
DPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94223
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
H2AZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70368
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70116
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53593
Speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03541
ANKRD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87733
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3438
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0321
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00725
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Classical_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73519
Lysosomal storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22957
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3679
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.7293
Lipid storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53731
GSE93918_2_v_0_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213632_3_v_5_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0181
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7074
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0093
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.993
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_16562_KO_Atrx_SRP308209	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03548
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53493
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5365_KO_Mettl14_SRP297324	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.28906
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77503
Metabolic dysfunction-associated steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.946
Vesicoureteral reflux	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1846
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61342
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89325
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.569
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5762
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03155
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61916
GGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10859
TBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46002
Articulation disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null