association dataset threshold value standardized value SNAI2_01_225 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.21239 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11764 KG1C CCLE Cell Line Gene Expression Profiles -1.0 -1.83006 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.864492 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 2.15739 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OB-17-DQ74_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.541663 8505C DepMap CRISPR Gene Dependency 1.0 2.41443 KMS11 DepMap CRISPR Gene Dependency 1.0 2.03504 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.11276 THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.8675 hsa-miR-4663 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.73104 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68646 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MA-25-RP17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.234336 True leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.509 ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.860354 SFPI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE226115,GSE226116_1_v_0_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C32 CCLE Cell Line Gene Expression Profiles 1.0 1.6757 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18426 SKLMS1 CCLE Cell Line Gene CNV Profiles -1.0 -2.08859 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0275 Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49144 Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824761 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06863 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.792 BB-20-UU03_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.277773 Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JA-85-SW39_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.293414 Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.51884 GD-82-CS38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.86859 Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34006 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17316 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11604 DE-98-FC24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.284617 GSE213650_3_v_1_everolimus_human RummaGEO Drug Perturbation Signatures -1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.826152 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5970-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.186 AA-62-OC45_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.321818 HS729 CCLE Cell Line Gene Expression Profiles -1.0 -1.48726 DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64461 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6523 NCIH1568 CCLE Cell Line Gene CNV Profiles 1.0 1.51411 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 Lung adenocarcinoma_LUAD_TCGA-75-6203-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37526 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.03961 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20893 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33027 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE135030_3_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null SNU1214 CCLE Cell Line Gene Expression Profiles 1.0 2.65492 BC-56-CP81_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.245929 CB-88-LG34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.206219 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.69399 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Sublingual squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.554 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8368 NCI-H2009 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90881 FLI1-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-4478 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CD-20-GE75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.332451 hsa-miR-4419b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 NCIH929 CCLE Cell Line Gene CNV Profiles 1.0 1.58017 Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HO-1-u-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.554 Psoriasis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4516 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 AC-05-MR83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.275601 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39603 GSU DepMap CRISPR Gene Dependency 1.0 2.34384 EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 101.171 SF767 CCLE Cell Line Gene Expression Profiles 1.0 1.96033 Gingival cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.784 Brain - Hippocampus GTEx Tissue Gene Expression Profiles 2023 1.0 3.39882 GSE135030_3_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.920489 Lung adenocarcinoma_LUAD_TCGA-05-4434-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHOM2B CCLE Cell Line Gene Expression Profiles -1.0 -2.19025 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein binding GO Molecular Function Annotations 2015 1.0 null DMS53 DepMap CRISPR Gene Dependency 1.0 2.04262 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.33697 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05433 Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3487 Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DU-145 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2218 CCLE Cell Line Gene CNV Profiles 1.0 1.78351 RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6469 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.883942 anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11136 SALE CCLE Cell Line Gene Expression Profiles 1.0 2.40871 multicellular organismal process GO Biological Process Annotations 2015 1.0 null Connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.275 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.36041 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.888699 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75566 KMS28BM CCLE Cell Line Gene CNV Profiles 1.0 1.70706 EBC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.6317 TE15 CCLE Cell Line Gene CNV Profiles -1.0 -2.14207 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Metatarsal bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51652 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.938659 ovary GTEx Tissue Gene Expression Profiles -1.0 -1.07322 NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.9786 CORL279 CCLE Cell Line Gene Expression Profiles -1.0 -3.27665 MB-15-ZF03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.53124 NE-92-EU87_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.259046 COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 dorsolateral prefrontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51309 BECKER CCLE Cell Line Gene Expression Profiles -1.0 -1.72683 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853266 HF-91-IU60_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.285459 PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-FRA1_DN_FOSL1 Rummagene Transcription Factor Associations 2026 1.0 null TFK1 DepMap CRISPR Gene Dependency 1.0 2.19276 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99219 BD-49-MD69_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.804302 EHEB CCLE Cell Line Gene Expression Profiles 1.0 1.79271 SUDHL1 DepMap CRISPR Gene Dependency 1.0 2.24509 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86961 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null u266b1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 hsa-miR-4665-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 496100426_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.50086 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C1-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 AC-56-ZV05_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.215952 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905776 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.94943 orbital frontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30381 BHY CCLE Cell Line Gene CNV Profiles -1.0 -1.38398 FD-20-OG99_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.432948 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 KM12 CCLE Cell Line Gene Expression Profiles 1.0 1.60005 BE-04-AN21_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.295282 hsa-miR-1233 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HCC202 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.875028 P31FUJ DepMap CRISPR Gene Dependency 1.0 2.10051 NA-30-HS87_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.44643 vitamin e_mus musculus_gpl1261_gse42813 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03931 striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75909 area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.47405 IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87269 Atopic dermatitis 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.454 RAJI CCLE Cell Line Gene Expression Profiles 1.0 1.36597 TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null range GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE215086_0_v_1_batf_human RummaGEO Gene Perturbation Signatures -1.0 null TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4637-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135030_8_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null 496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.60397 primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15743 AA-68-OJ16_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.362862 GSE135030_8_v_10_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null FC-85-OX77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.3273 PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2716-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05366 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893472 Lung squamous cell carcinoma_LUSC_TCGA-60-2715-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null Late cornified envelope protein InterPro Predicted Protein Domain Annotations 1.0 null HUT102 CCLE Cell Line Gene Expression Profiles 1.0 1.92685 GSE131903_0_v_2_abca12_human RummaGEO Gene Perturbation Signatures -1.0 null 496100469_TCx_no dementia_TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.99952 Developmental Biology Reactome Pathways 2024 1.0 null BB-20-UU03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.620697 EJM COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-5232-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AB-64-ZX70_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.92277 PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF Rummagene Transcription Factor Associations 2026 1.0 null ZR751 CCLE Cell Line Gene CNV Profiles 1.0 1.39073 Focal nonepidermolytic palmoplantar keratoderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.952 EOL-1-CELL COSMIC Cell Line Gene Mutation Profiles 1.0 null MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2189 Keratohyalin granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.445 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-420-BCL6B_BCL6B Rummagene Transcription Factor Associations 2026 1.0 null KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.66737 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36449 GSE186440,GSE186443_1_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null GSE135686_2_v_3_etomoxir_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0428 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5325 NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 2.28228 RC-52-AC88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.266368 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SOX9_01_309 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59946 GSE118077_4_v_2_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null BRL cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.702 Ichthyosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.519 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.989131 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5120-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TF-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49944 hsa-miR-3202 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Rge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.699 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03974 Testicular leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.032 NCI-H345 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09862 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63804 NCIH1437 CCLE Cell Line Gene CNV Profiles 1.0 2.831 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9825 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.28718 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62125 Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JVM3 CCLE Cell Line Gene Expression Profiles 1.0 2.02608 MLXIPL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2714 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1283 Disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58107 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GE-98-ZI68_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.482848 Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15743 H2AFZ ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72567 AA-85-LB25_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.211477 Stratum spinosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.796 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0012 Skin disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.661 GA-88-CF36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.357313 POLR2AphosphoS5_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21091 EHF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2637 OF-05-CB18_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.517312 Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HHUA DepMap CRISPR Gene Dependency 1.0 2.22146 AD-16-HL96_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.278753 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.977213 BCPAP CCLE Cell Line Gene CNV Profiles -1.0 -1.88885 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25219 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9248 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Small proline-rich protein/late cornified envelope protein InterPro Predicted Protein Domain Annotations 1.0 null KATOIII DepMap CRISPR Gene Dependency 1.0 2.42563 Haustorium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.72 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8305 amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.64852 Brain Lower Grade Glioma_LGG_TCGA-DU-5853-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.909258 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7531 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.3935 GRANTA519 CCLE Cell Line Gene Expression Profiles 1.0 1.71332 MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -1.67212 EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.475431 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01785 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.72689 Autoimmune disease of musculoskeletal system DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.512 GNPNAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14977 CB-62-TB77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.37298 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5287 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.0647 Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DC-47-KV62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.41767 MZ in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.897737 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null NCIH2009 DepMap CRISPR Gene Dependency 1.0 2.0403 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1778 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 HNF4A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.0747 Contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.545 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890919 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.202 NCI-H1876 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1914 KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.52387 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05426 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.389 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68756 PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.833191 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE189789_0_v_1_oridonin_human RummaGEO Drug Perturbation Signatures 1.0 null RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4818 GD-82-CS38_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.515249 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null XE-69-AT35_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.396976 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4573 KMS20 CCLE Cell Line Gene CNV Profiles 1.0 1.79254 Cornified envelope formation KEGG Pathways 2026 1.0 null RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.5618 KARPAS299 CCLE Cell Line Gene CNV Profiles -1.0 -2.69407 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.474 Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null magnocellular (medial) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16728 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OC-53-QX76_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.211301 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87811 col7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.644 NCIH1395 CCLE Cell Line Gene CNV Profiles 1.0 2.69495 ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3052 GA-94-MC54_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.336295 Leprosy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.125 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09598 Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1937 CCLE Cell Line Gene CNV Profiles -1.0 -2.12674 hsa-miR-4723-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 KMRC20 DepMap CRISPR Gene Dependency 1.0 2.32302 MEL290 DepMap CRISPR Gene Dependency 1.0 2.28494 KNS42 CCLE Cell Line Gene CNV Profiles -1.0 -1.85645 HUPT4 DepMap CRISPR Gene Dependency 1.0 2.21009 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5988 Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H810 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 Primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 EKVX CCLE Cell Line Gene CNV Profiles 1.0 1.47028 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.7953 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87698 nomenclature GeneRIF Biological Term Annotations 1.0 null GD-82-CS38_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.29062 KE97 CCLE Cell Line Gene Expression Profiles 1.0 1.45662 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05426 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE138938_1_v_3_foxp2_human RummaGEO Gene Perturbation Signatures 1.0 null AB-12-IS33_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.225881 Lung squamous cell carcinoma_LUSC_TCGA-85-7698-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844338 Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3187-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849096 SOX5 JASPAR Predicted Transcription Factor Targets 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autoimmune disease of skin and connective tissue DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.597 AE-19-BK71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.17492 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.58216 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03072 ST486 DepMap CRISPR Gene Dependency 1.0 2.28851 GSE213650_0_v_1_everolimus_human RummaGEO Drug Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epidermolytic hyperkeratosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.046 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE135030_11_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null AC-35-CK01_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 3.50656 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49184 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29125 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.98202 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03931 Mouth floor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE219274,GSE219276_3_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE215086_5_v_0_batf_human RummaGEO Gene Perturbation Signatures 1.0 null EA-84-SC49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.401701 HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.63909 TP63 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.221 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08883 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54034 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GD-66-XE49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.261748 skin GTEx Tissue Gene Expression Profiles 1.0 2.18987 ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.5897 Dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.494 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75723 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889935 Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.52218 BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52969 RPMI-7951 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884531 PMC9512540__F3 PFOCR Pathway Figure Associations 2024 1.0 null GSE175787_5_v_9_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null SF126 CCLE Cell Line Gene CNV Profiles -1.0 -2.78721 KMS21BM CCLE Cell Line Gene Expression Profiles 1.0 1.40273 ED-32-VE54_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.218655 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841655 Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100466_PCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.08771 HMEL CCLE Cell Line Gene Expression Profiles 1.0 1.76092 NC-52-AG88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.430805 HCC2157 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 TE10 CCLE Cell Line Gene CNV Profiles -1.0 -1.39223 TE-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.934146 ICC9 DepMap CRISPR Gene Dependency 1.0 2.62517 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25845 SP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.828126 REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1176 hsa-miR-4687-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 cas1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.903 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4266 AD-18-XC14_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.578943 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36308 AC-55-XA97_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.40604 Ichthyosis vulgaris DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.164 Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5426 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3178 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LE-40-JW92_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.497928 Palmoplantar keratosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.225 Desmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.279 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905776 PECAPJ49 CCLE Cell Line Gene CNV Profiles -1.0 -2.11694 JVM2 CCLE Cell Line Gene Expression Profiles 1.0 1.49787 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.89491 Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null S0-EE-Y7IR_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.280427 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.06758 TE-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 tissues GeneRIF Biological Term Annotations 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31726 GSE215086_8_v_7_batf_human RummaGEO Gene Perturbation Signatures -1.0 null GC-04-UF36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.288251 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87269 Nonepidermolytic palmoplantar keratoderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.209 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2507 SFPI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Proteasome storage granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.551 Allergic contact dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.559 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR_01_278 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.19384 Wnt-Frizzled-LRP5/6 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.587 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4541 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6918 molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.923476 hsa-miR-1275 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03931 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.104 adipose tissue GTEx Tissue Gene Expression Profiles 1.0 0.956651 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.989131 Lung squamous cell carcinoma_LUSC_TCGA-94-8035-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135030_11_v_4_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.82645 outer CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.970364 PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1703 KMS11 CCLE Cell Line Gene CNV Profiles 1.0 1.56303 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.847791 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37621 PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75566 Brain Lower Grade Glioma_LGG_TCGA-DH-5142-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1 ChEA Transcription Factor Targets 1.0 null HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1083 Brain Lower Grade Glioma_LGG_TCGA-HT-7467-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null GC-04-UF36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.245649 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C-33A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.632 VC-19-YG34_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.237728 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17926 Lung squamous cell carcinoma_LUSC_TCGA-98-8021-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45149 NFKB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9973 deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39047 BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Keratinocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.8 dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.908414 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06421 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.877 PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A Rummagene Transcription Factor Associations 2026 1.0 null MDA-MB-453 COSMIC Cell Line Gene Mutation Profiles 1.0 null RD CCLE Cell Line Gene Expression Profiles -1.0 -1.96067 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FD-62-ZB67_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.350919 AC-55-XA97_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.784909 Stratum corneum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.585 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9547 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null extracellular region LOCATE Predicted Protein Localization Annotations 1.0 null stratum pyramidale of rostral CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.888257 BB-84-DG64_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.588884 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.51444 ZNF274_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827316 LD-39-FL02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.691876 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.68243 irf6_17041601_skin_lof_mouse_gpl1261_gds2359 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.099911 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13377 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18426 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07917 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cornified envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.611 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9392 NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929603 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-O2-A52V-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884223 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.880253 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78413 COV318 DepMap CRISPR Gene Dependency 1.0 2.28735 Lung squamous cell carcinoma_LUSC_TCGA-85-8052-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23835 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-548s TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Rectum adenocarcinoma_READ_TCGA-F5-6861-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOS COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 JL1 DepMap CRISPR Gene Dependency 1.0 2.23061 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5247 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11725 FXR MotifMap Predicted Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC-62-AQ92_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.707805 PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF Rummagene Transcription Factor Associations 2026 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 SB-75-UH17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.270885 Cervical mucus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.681 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9557 GA-28-SS67_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.380409 AB-74-VK99_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.54462 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RG-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null CC-03-PW00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.602655 WM793 DepMap CRISPR Gene Dependency 1.0 2.0646 Stratified epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.83 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4244-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myositis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.133 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Autoimmune disease of skin and connective tissue DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 QA-81-IM40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.64166 GSE135030_3_v_9_fludarabine_human RummaGEO Drug Perturbation Signatures -1.0 null S100A9 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.463 Keratinization Reactome Pathways 2024 1.0 null 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null L428 DepMap CRISPR Gene Dependency 1.0 2.28388 biological_process GO Biological Process Annotations 2015 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955865 NB1 CCLE Cell Line Gene CNV Profiles 1.0 1.49943 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.31035 TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7229 Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1703 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 Rectum adenocarcinoma_READ_TCGA-CI-6622-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6731 plastid-encoded plastid RNA polymerase complex B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.477 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.90994 KMCH1 DepMap CRISPR Gene Dependency 1.0 2.18873 H4K20me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8331-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RB-34-TO07_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.357977 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cotyledon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.921 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.879582 Stratum granulosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.899 Brain Lower Grade Glioma_LGG_TCGA-DB-A4XC-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HPAFII DepMap CRISPR Gene Dependency 1.0 2.0576 QE-00-EB96_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.255673 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8533 hsa-miR-4539 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 H3K4me1_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.25669 REST ChEA Transcription Factor Targets 1.0 null jvm2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.539 CFPAC1 CCLE Cell Line Gene Expression Profiles -1.0 -2.02013 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890574 developmental process GO Biological Process Annotations 2015 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18533 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4555 2.2.15 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.745 AMO1 CCLE Cell Line Gene CNV Profiles 1.0 1.69503 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BD-11-DV28_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.459978 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.885403 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH23 CCLE Cell Line Gene Expression Profiles -1.0 -1.55295 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87269 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0936 Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hypodermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08883 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71693 TE1 CCLE Cell Line Gene Expression Profiles -1.0 -2.22516 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844338 ONE58 DepMap CRISPR Gene Dependency 1.0 2.24227 posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.855059 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00298 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66003 KA-29-AB08_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.913383 BE-31-XV38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.87649 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0864 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.51634 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AD-18-XC14_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.53154 ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01439 CAL120 CCLE Cell Line Gene CNV Profiles -1.0 -1.4383 FB-66-UU47_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.204848 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45975 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A4EM-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.59651 FC-22-VC55_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.40222 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.850301 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32383 GSE171572_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.7369 ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.817 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25621 HCC1171 CCLE Cell Line Gene CNV Profiles 1.0 1.98674 Corneocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.437 CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Allergic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.302 GSE175787_13_v_9_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74212 LD-69-ZV56_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.22136 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Asthma or allergic disease (pleiotropy) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.830103 Recessive dystrophic epidermolysis bullosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.162 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.999646 NA-16-OJ70_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.26636 Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE215086_3_v_0_batf_human RummaGEO Gene Perturbation Signatures 1.0 null keratinization GO Biological Process Annotations 2015 1.0 null PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR Rummagene Transcription Factor Associations 2026 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4605 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827786 Lens epithelial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.148 CMLT1 CCLE Cell Line Gene Expression Profiles -1.0 -1.96854 Formation of the cornified envelope Reactome Pathways 2024 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28362 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11604 TP63 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.2875 Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13918 Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 1.0 6.29604 LPS853 DepMap CRISPR Gene Dependency 1.0 2.22546 Petiole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.935 GABPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0428 single-organism developmental process GO Biological Process Annotations 2015 1.0 null MAT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71858 MZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06991 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8314 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles 1.0 2.01459 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8176 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.924577 SOX9_01_308 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59946 Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.368 HOS CCLE Cell Line Gene CNV Profiles 1.0 1.62919 SCC9 CCLE Cell Line Gene Expression Profiles 1.0 3.40807 Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KA-75-LP02_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.587992 PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5 Rummagene Transcription Factor Associations 2026 1.0 null HCA1 DepMap CRISPR Gene Dependency 1.0 2.1319 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.08 TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0247 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4322 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3239 Autoimmune disease of musculoskeletal system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PATU8902 DepMap CRISPR Gene Dependency 1.0 2.00287 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1997 TF-29-QU48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.18849 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919074 BT-483 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1990 DepMap CRISPR Gene Dependency 1.0 2.1171 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2584 WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939464 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U-373MG cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 describing GeneRIF Biological Term Annotations 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988047 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.051 MYC ENCODE Transcription Factor Targets 1.0 null SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.49242 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957217 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H3122 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Salivary gland cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08128 PMC9195629-Table1.xlsx-Supplementary_Table_1-C-FOS_FOS Rummagene Transcription Factor Associations 2026 1.0 null OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.833357 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16761 BE-04-AN21_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.80938 inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37235 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.997739 Keratin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.595 GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNU5 DepMap CRISPR Gene Dependency 1.0 2.1571 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE153871_4_v_2_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null KE-73-XV62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.349875 Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CJM CCLE Cell Line Gene CNV Profiles -1.0 -1.59655 143B DepMap CRISPR Gene Dependency 1.0 2.21094 NCIH2342 CCLE Cell Line Gene Expression Profiles -1.0 -2.88745 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC95 CCLE Cell Line Gene CNV Profiles -1.0 -1.59538 Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EB-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937349 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17017 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.496 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08883 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882752 H9 COSMIC Cell Line Gene Mutation Profiles 1.0 null ETS1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null 496100458_FWM_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13487 EHF_01_147 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.8967 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 7.65926 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BB-11-JI42_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.493004 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1422 FF-90-JK74_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.249481 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.82186 NCIH747 DepMap CRISPR Gene Dependency 1.0 2.30319 MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.46643 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.55771 basal nucleus of Meynert Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.833874 HS611T CCLE Cell Line Gene Expression Profiles 1.0 1.35757 GAMG CCLE Cell Line Gene Expression Profiles -1.0 -2.51161 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GA-88-CF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.263488 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33012 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.40625 YE-80-LN04_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.375282 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.664 vagina GTEx Tissue Gene Expression Profiles 1.0 1.10882 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A1207 CCLE Cell Line Gene Expression Profiles 1.0 1.40487 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE171572_5_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null changes GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A7DR-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3175 Psoriasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.645 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DC-47-KV62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.06085 hsa-miR-219-1-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CF-24-KQ98_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.84448 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AD-99-SN88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.980154 H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.73681 HE-80-BQ08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.895298 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61693 P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6756 NCIH1648 DepMap CRISPR Gene Dependency 1.0 2.17257 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.025 Dami cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.67 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mal de Meleda DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.568 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.859 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07206 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Upper epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 OPM2 CCLE Cell Line Gene CNV Profiles 1.0 1.67306 doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CB-32-EI69_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.609909 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9458 AA-85-LB25_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.276105 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8706 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06508 STAT3 ENCODE Transcription Factor Targets 1.0 null SCC25 CCLE Cell Line Gene Expression Profiles -1.0 -1.46119 Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ca9-22 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.793 MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.884531 POLR2A ENCODE Transcription Factor Targets 1.0 null stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32032 SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08883 SUPHD1 CCLE Cell Line Gene Expression Profiles 1.0 1.49875 CAPAN1 DepMap CRISPR Gene Dependency 1.0 2.25242 CAL62 DepMap CRISPR Gene Dependency 1.0 2.10759 LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2159 FD-62-ZB67_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.917198 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0063 SKES1 CCLE Cell Line Gene Expression Profiles 1.0 1.85387 Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.917063 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.65481 Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.359 BE-79-QU25_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.234404 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70U-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42852 RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.940225 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18426 MJ CCLE Cell Line Gene Expression Profiles 1.0 2.22704 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01283 HSD17B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68897 Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A89H-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Omega speckle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.971 AC-36-TL21_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.975605 IA-27-CK10_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.210495 Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 16643655-1300GenesList GeneSigDB Published Gene Signatures 1.0 null 59M DepMap CRISPR Gene Dependency 1.0 2.23017 inner CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15626 GSE184892_4_v_2_trehalose_human RummaGEO Drug Perturbation Signatures 1.0 null GSE171572_3_v_4_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865757 Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.98602 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.05553 TE159T CCLE Cell Line Gene Expression Profiles -1.0 -1.47776 BE-69-RD44_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.2366 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.92581 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16413 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988047 YMB1 CCLE Cell Line Gene CNV Profiles 1.0 1.67351 GSE139540_4_v_1_menadione_human RummaGEO Drug Perturbation Signatures 1.0 null BD-73-TX58_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.549812 CF-24-KQ98_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 2.19188 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.165 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE219274,GSE219276_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH2452 DepMap CRISPR Gene Dependency 1.0 2.06188 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.973703 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brahma complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.12 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6241 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.17026 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 2.05249 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47813 binding GO Molecular Function Annotations 2015 1.0 null ventral posterior inferior nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25123 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01353 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05426 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8908 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.7227 BB-20-UU03_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.330295 CC-03-PW00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.760519 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GC-04-UF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.294998 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835444 Cell envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.056 inner CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41421 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.992538 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921573 Cutaneous lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.77 LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.15164 EGR4_01_132 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.93948 Integrator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.871 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08883 ERG ChEA Transcription Factor Targets 1.0 null FB-98-HM88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.46077 NCI-H1993 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30624 MM1S COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KA-63-FH23_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.209762 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1531 Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5358-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32383 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.991009 Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.944874 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88511 RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SNU620 DepMap CRISPR Gene Dependency 1.0 2.27805 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.1708 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34999 plastid-encoded plastid RNA polymerase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.085 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.985 DCTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02584 XE-69-AT35_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.31398 paper GeneRIF Biological Term Annotations 1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.01545 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null D502MG DepMap CRISPR Gene Dependency 1.0 2.00291 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9349 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86961 18614019-TableS4c GeneSigDB Published Gene Signatures 1.0 null LNZTA3WT4 DepMap CRISPR Gene Dependency 1.0 2.21666 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06623 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6229-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23925 Integumentary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.653 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60178 BB-86-BE19_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.212606 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.243 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TC32 CCLE Cell Line Gene Expression Profiles 1.0 1.34926 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02612 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01353 Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 GSE184892_7_v_2_trehalose_human RummaGEO Drug Perturbation Signatures 1.0 null Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.36 HUNS1 DepMap CRISPR Gene Dependency 1.0 2.42497 striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.909258 Epidermolysis bullosa dystrophica DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0616 primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.32695 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75443 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65466 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65145 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H2-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NA-16-OJ70_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.4944 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8884 SKMEL31 CCLE Cell Line Gene CNV Profiles -1.0 -1.88052 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOS-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 RBPJ ChEA Transcription Factor Targets 1.0 null BB-44-SX65_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.30081 Poisoning CTD Gene-Disease Associations 1.0 1.24781 Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Salivary gland tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.113 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.888821 GRHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5677 Hypodermal seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 Lupus erythematosus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6789 TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5027 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25344 SUDHL8 CCLE Cell Line Gene Expression Profiles 1.0 1.34767 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18533 HCC1588 CCLE Cell Line Gene Expression Profiles 1.0 1.57192 Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.558 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62751 SW 527 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.833357 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.79404 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827755 Lung squamous cell carcinoma_LUSC_TCGA-85-6175-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DA-33-BM26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.280012 CC-03-PW00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.869155 ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7115-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.787112 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-6798-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUPT1 DepMap CRISPR Gene Dependency 1.0 2.3755 PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15046 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.936871 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988047 HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.74888 TA-10-KH35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.990174 Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AC-36-TL21_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.491645 LD-69-ZV56_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.384324 Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.838 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.91276 SCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.7289 Alevin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.624 AF-11-IL39_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.203921 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.06238 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4827 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4963-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H376 DepMap CRISPR Gene Dependency 1.0 2.39357 HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.853684 ZNF274 ENCODE Transcription Factor Targets 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42814 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45149 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18811 Bpe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87269 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68893 AA-56-JY17_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.31567 Esophageal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.75 JHOS-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35003 Necrosis CTD Gene-Disease Associations 1.0 1.06881 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836805 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.965546 SW1088 CCLE Cell Line Gene Expression Profiles -1.0 -1.47502 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9886 CB-44-RT90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.13085 MA-06-DJ95_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.23885 Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.6791 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NCIH1048 DepMap CRISPR Gene Dependency 1.0 2.09953 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3471 A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.56082 FB-66-UU47_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.204529 NCIH2291 DepMap CRISPR Gene Dependency 1.0 2.34423 Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.838 VC-19-YG34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.753928 NCI-H1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.30944 Dermatomyositis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.279 BA-68-FJ41_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.76757 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.11455 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8748 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6922 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.888147 FD-62-ZB67_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.03947 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3929 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GA-28-SS67_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.820295 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25968 HC-92-HE59_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.09316 layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50633 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14571 PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53 Rummagene Transcription Factor Associations 2026 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.67111 OCUM1 CCLE Cell Line Gene Expression Profiles 1.0 1.48879 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7845 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01045 SE-15-AV21_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.241591 OC-10-FB51_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.44951 SPI1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KHM1B CCLE Cell Line Gene CNV Profiles 1.0 2.14052 SPI1 ENCODE Transcription Factor Targets 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4584 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37096 LD-69-ZV56_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.57217 LNZ308 CCLE Cell Line Gene CNV Profiles 1.0 1.36073 Leptospirosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.626 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.988395 HS683 CCLE Cell Line Gene Expression Profiles -1.0 -1.47553 wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.251151 Lung squamous cell carcinoma_LUSC_TCGA-58-A46N-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ST486 CCLE Cell Line Gene CNV Profiles 1.0 1.33813 SB-94-ZA83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.211703 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8671 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RANBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70862 LK2 CCLE Cell Line Gene CNV Profiles 1.0 1.55417 IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09533 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988047 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.93638 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FF-34-KW62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.330164 DC-91-ME12_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.319763 Papilloma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.712 primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02657 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.846523 GSE135030_8_v_7_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.735 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55551 Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51X-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00988 BE-31-XV38_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.397711 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.36449 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.833357 LN443 CCLE Cell Line Gene CNV Profiles -1.0 -1.40168 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5373-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AC-36-TL21_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 2.13258 vitamin c_homo sapiens_gpl570_gse11919 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU638 DepMap CRISPR Gene Dependency 1.0 2.06276 laminin-5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.819 LB771HNC DepMap CRISPR Gene Dependency 1.0 2.39119 GCM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5299 outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.00515 GSE118077_1_v_2_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null Atopic dermatitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.551 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.69967 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.46009