association	dataset	threshold value	standardized value
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845373
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.847
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
MON1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24841
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32977
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65303
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01386
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5557
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95296
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19474
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10315
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75348
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5661
OBSCN	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73738
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0919
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.45825
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889778
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10669
MAGEB10	Pathway Commons Protein-Protein Interactions	1.0	null
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32669
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46578
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865205
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41818
GOS3	CCLE Cell Line Gene CNV Profiles	1.0	1.43396
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PLAGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45673
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01214
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2578
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77704
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966982
ABRA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53928
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15346
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937669
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980364
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.65271
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47579
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934963
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1135
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11169
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5518
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03999
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
SEC11C	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953871
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35252
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958726
Interstitial nucleus of Cajal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11962
Doyne honeycomb retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12781
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998761
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14419
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30199
DDX24	Pathway Commons Protein-Protein Interactions	1.0	null
FRMPD4	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
CLSTN1	Pathway Commons Protein-Protein Interactions	1.0	null
HS746T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58889
KBTBD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60327
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
SMARCA5	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850124
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-MYOD1_MYOD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00954
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10601
inferior occipital gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869459
KAT2B	ENCODE Transcription Factor Targets	1.0	null
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18187
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.35428
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08489
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1634
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54658
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27971
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF330	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17699
POLR3A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51213
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12876
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00637
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48168
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10528
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
testis	HPA Tissue Protein Expression Profiles	1.0	0.92544
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06133
ECC10	CCLE Cell Line Gene Expression Profiles	1.0	1.42537
PECAPJ15	CCLE Cell Line Gene Expression Profiles	1.0	1.55534
organic acid transport	GO Biological Process Annotations 2015	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
GSE220806_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMTN	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49055
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928096
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23436
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54768
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65867
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86697
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59221
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62177
FEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52078
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945755
CALCOCO2	Pathway Commons Protein-Protein Interactions	1.0	null
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.612
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7413
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.862364
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02086
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
NPC1L1	Pathway Commons Protein-Protein Interactions	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6129
SKRC31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72749
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07915
skin	GTEx Tissue Gene Expression Profiles	-1.0	-1.0505
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01718
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00736
LS1034	CCLE Cell Line Gene Expression Profiles	1.0	1.69991
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851461
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867077
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970208
Sarcoma_SARC_TCGA-3B-A9HP-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59268
MAX	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
MYO1D	Pathway Commons Protein-Protein Interactions	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56385
RAD50	Pathway Commons Protein-Protein Interactions	1.0	null
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937669
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.50273
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01975
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30502
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65758
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14031
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
IFT27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02249
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15928
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59808
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
Keratoconus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
RCOR1_02_204	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
Nucleus of Darkschewitsch	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35617
MOLM6	CCLE Cell Line Gene CNV Profiles	1.0	1.91334
POLG	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06138
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00843
DENND3	Pathway Commons Protein-Protein Interactions	1.0	null
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07066
HNF4A	ChEA Transcription Factor Targets	1.0	null
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2992
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02152
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.81698
MOLM14	DepMap CRISPR Gene Dependency	1.0	3.50331
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
GTSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
NRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07055
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	1.57123
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38752
KANK2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14258
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21689
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
C1orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69959
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39756
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838173
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42705
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEX11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57445
PRG4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17812
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2289_OE_NRP1_SRP124497	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.71672
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.36723
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04237
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910688
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.064
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34197
LMNB1_02_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
MARVELD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19434
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59001
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56995
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	184.222
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14067
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970907
PITX2	Pathway Commons Protein-Protein Interactions	1.0	null
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967409
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92203
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60628
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
NUP98	Pathway Commons Protein-Protein Interactions	1.0	null
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9557
SNX19	Pathway Commons Protein-Protein Interactions	1.0	null
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34985
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30199
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.4659
MKL1	Pathway Commons Protein-Protein Interactions	1.0	null
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82064
CEP170	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0261
periventricular stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26774
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71035
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12876
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30108
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.06145
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66009
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56719
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PDLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42155
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12143
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2176
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74069
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4173
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMT2A	Pathway Commons Protein-Protein Interactions	1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1227
MAP3K1	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.45952
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843701
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00167
transport	GO Biological Process Annotations 2015	1.0	null
DNAJB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99789
GTEX-P4QS-2026-SM-3NMCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873501
ERP44	Pathway Commons Protein-Protein Interactions	1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79168
BACH1	ENCODE Transcription Factor Targets	1.0	null
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01352
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923258
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.32783
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2202
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80791
postcentral gyrus, left, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00358
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74386
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23139
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56702
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78681
CDC42EP1	Pathway Commons Protein-Protein Interactions	1.0	null
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41659
PFDN2	Pathway Commons Protein-Protein Interactions	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5843
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24432
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99361
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53962
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.916015
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47228
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06438
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10269
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996584
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35036
ELMSAN1	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45181
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08869
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24356
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948212
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09898
SACS	Pathway Commons Protein-Protein Interactions	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.17738
PGD	Pathway Commons Protein-Protein Interactions	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13584
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956732
KIF12	Pathway Commons Protein-Protein Interactions	1.0	null
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8402
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22431
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.5075
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05601
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868609
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87925
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08629
MRPL14	Pathway Commons Protein-Protein Interactions	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5588
E2F6_02_205	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.45943
FAM193B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34856
C75	DepMap CRISPR Gene Dependency	1.0	4.0657
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836689
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	CCLE Cell Line Gene CNV Profiles	1.0	1.69903
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80298
RPRD2	Pathway Commons Protein-Protein Interactions	1.0	null
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69238
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53248
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53228
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884881
single-organism localization	GO Biological Process Annotations 2015	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23996
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30835
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.69693
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IGDCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41634
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866557
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906545
MAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62474
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907013
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21655
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35786
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69049
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_02_192	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.814
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28256
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22167
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54305
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34926
SMAD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5566
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50858
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61981
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89377
ZNF211	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38419
MOLM13	DepMap CRISPR Gene Dependency	1.0	2.24169
GTEX-TMMY-0626-SM-33HBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994164
SMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52436
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99069
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06011
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61647
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837333
ZBTB18	Pathway Commons Protein-Protein Interactions	1.0	null
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
H2AFZ	Pathway Commons Protein-Protein Interactions	1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.01249
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25396
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLEC11A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30932
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65635
long-chain fatty acid transport	GO Biological Process Annotations 2015	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47838
ACACB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944098
BRCA1	ENCODE Transcription Factor Targets	1.0	null
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
INSM1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4405
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.1258
PRRC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35368
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11033
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49187
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.9766
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.24797
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890377
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3739
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF	Pathway Commons Protein-Protein Interactions	1.0	null
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62328
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07244
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3081
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.7009
NEUROD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4669
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55984
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31229
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.201
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902817
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66764
NB17	DepMap CRISPR Gene Dependency	1.0	3.43548
Warburg micro syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.02584
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18285
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2975
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60999
isoprenoid binding	GO Molecular Function Annotations 2015	1.0	null
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30059
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62732
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7223
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950281
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17432
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
hsa-miR-4316	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4049
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891711
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5674
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58543
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1457
PREX2	Pathway Commons Protein-Protein Interactions	1.0	null
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20566
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995796
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18185
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.048772
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01602
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06119
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892815
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988969
monocarboxylic acid binding	GO Molecular Function Annotations 2025	1.0	null
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19628
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974622
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42164
Spear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06624
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6074
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DERL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79353
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56837
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36976
DNAH8	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB453	DepMap CRISPR Gene Dependency	1.0	2.75351
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06661
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4223
CXADR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77458
MAP3K7	Pathway Commons Protein-Protein Interactions	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.9953
SOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14203
ST6GALNAC6	Pathway Commons Protein-Protein Interactions	1.0	null
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65783
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
20460173-ImmPortAntimicrobials	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.74295
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32103
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.57293
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964184
YAF2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
CBFB	Pathway Commons Protein-Protein Interactions	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.249496
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27058
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10173
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PALD1	Pathway Commons Protein-Protein Interactions	1.0	null
PHF6	Pathway Commons Protein-Protein Interactions	1.0	null
Preputial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871691
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.43328
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
fatty acid transport	GO Biological Process Annotations 2015	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71514
GNPDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47534
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72006
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64428
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27456
placenta	HPA Tissue Protein Expression Profiles	1.0	0.92544
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	3.97118
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.03575
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0092
Lung adenocarcinoma_LUAD_TCGA-05-4420-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
ETV6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2069
ZNF235	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43123
SGOL2	Pathway Commons Protein-Protein Interactions	1.0	null
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94036
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61647
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96959
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954382
CDV3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16154
GSS	DepMap CRISPR Gene Dependency	1.0	2.3472
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06632
TRAK1	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP7D1	Pathway Commons Protein-Protein Interactions	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.66014
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81406
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14612
GLB1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88995
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Esophageal squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4579
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	1.97894
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19713
TPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62999
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3919
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36206
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.41375
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Calycin	InterPro Predicted Protein Domain Annotations	1.0	null
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13492
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
FZD10	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06278
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4444
CDC26	Pathway Commons Protein-Protein Interactions	1.0	null
MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77187
COLO680N	CCLE Cell Line Gene Expression Profiles	1.0	1.39032
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5345
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5921
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08629
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1	ENCODE Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04484
GTEX-XV7Q-0126-SM-4BRVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978037
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4546
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13155
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65478
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88009
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMYD4	Pathway Commons Protein-Protein Interactions	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.04389
GALK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31622
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01788
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88644
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958289
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39756
TXLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67228
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23203
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58298
ASF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03153
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33342
SUCLG1	Pathway Commons Protein-Protein Interactions	1.0	null
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
MAGI1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5252
DDX19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27055
EP400	Pathway Commons Protein-Protein Interactions	1.0	null
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45461
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.3414
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62328
MAATS1	Pathway Commons Protein-Protein Interactions	1.0	null
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
HBEGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55319
GPRC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82693
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28372
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18806
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58976
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.41
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28285
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38734
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82643
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2043
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
FTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71641
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40979
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
FOXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25571
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64243
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06278
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12019
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNOT4	Pathway Commons Protein-Protein Interactions	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3052
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27676
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.831229
ADGRG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79734
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05891
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05257
CDK5RAP2	Pathway Commons Protein-Protein Interactions	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0003
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
ANP32B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33643
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9282
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85509
HEC108	CCLE Cell Line Gene Expression Profiles	1.0	1.79713
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54712
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27108
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3943
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
FAAP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82428
ZBTB40	Pathway Commons Protein-Protein Interactions	1.0	null
Prostaglandin D synthase	InterPro Predicted Protein Domain Annotations	1.0	null
NAIP	Pathway Commons Protein-Protein Interactions	1.0	null
FN1	Pathway Commons Protein-Protein Interactions	1.0	null
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10236
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932604
CSF1	Pathway Commons Protein-Protein Interactions	1.0	null
OTUD4	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03426
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92016
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9719
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07404
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ATP5O	Pathway Commons Protein-Protein Interactions	1.0	null
retinoic acid binding	GO Molecular Function Annotations 2023	1.0	null
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7278
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46259
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6748
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4444
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.012173
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3688
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86565
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30232
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11464
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6066
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59513
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
U343	DepMap CRISPR Gene Dependency	1.0	3.65394
C18orf32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51478
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877696
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954104
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10601
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10783
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
anion transport	GO Biological Process Annotations 2015	1.0	null
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849875
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49438
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00084
monocarboxylic acid binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14066
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13101
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14028
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13846
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46289
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50359
a549	HPA Cell Line Gene Expression Profiles	1.0	0.836969
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM19	DepMap CRISPR Gene Dependency	1.0	2.26223
ESR1_T47D_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2678
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882247
ADAMTS20	Pathway Commons Protein-Protein Interactions	1.0	null
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88808
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADNP	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H2BM	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858882
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.57126
PROKR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72705
ADGRE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74709
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06462
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6612
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28723
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89137
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.5925
OVTOKO	DepMap CRISPR Gene Dependency	1.0	2.88974
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28843
BECKER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66523
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.4418
Irregular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36177
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
ZNF888	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20799
XRCC5_02_159	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56896
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW48	CCLE Cell Line Gene Expression Profiles	1.0	2.22001
NR3C1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4748	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MYLA	DepMap CRISPR Gene Dependency	1.0	3.84279
SCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53352
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7711
ARL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79443
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0518
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25731
layer 3 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17299
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30328
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96518
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41344
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907575
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41213
RBFOX2	Pathway Commons Protein-Protein Interactions	1.0	null
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30563
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29838
OPHN1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0226-SM-3NMD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878333
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12729234-10194_2025_2222_MOESM1_ESM.xlsx-Table_S6-Table_S6_MR_results_of_the_significant_genes_from_human_brain_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF586	Pathway Commons Protein-Protein Interactions	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.38417
UBXN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06424
Lung adenocarcinoma_LUAD_TCGA-49-4510-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.594
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65397
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.26072
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82841
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40726
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92136
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902428
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1734
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6025
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51087
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80543
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11312
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02664
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.01635
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RH-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4431731-pgen.1005211.s002.xlsx-ERG_TRISOMY-Unnamed_2_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994526
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60566
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7448
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33479
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.981897
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952783
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.4042
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.00205
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5512
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45213
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30919
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924374
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9308
ZNF541	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25843
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06166
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01285
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0839
H3F3A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PPP2R3B	Pathway Commons Protein-Protein Interactions	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10718
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.4129
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03958
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21322
carboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-2.4859
TNR	Pathway Commons Protein-Protein Interactions	1.0	null
OE33	DepMap CRISPR Gene Dependency	1.0	2.62038
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00799
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90649
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
Lung adenocarcinoma_LUAD_TCGA-78-7161-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11256
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965797
SNRPF	Pathway Commons Protein-Protein Interactions	1.0	null
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853577
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05209
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
cellular_component	GO Cellular Component Annotations 2015	1.0	null
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00043
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
CNTN5	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34387
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959879
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877454
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976972
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02589
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833136
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
Orphan transporters	Reactome Pathways 2014	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98863
NCDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PDHA2	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
chr9_136966179_C_T_b38	GTEx eQTL 2025	1.0	1.36411
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893822
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87678
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65284
CAMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57927
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50898
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
TGBC11TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.45802
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951693
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825515
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937669
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02134
SH3RF1	Pathway Commons Protein-Protein Interactions	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6633
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05616
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17561
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
SPRYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43304
RUNX2	Pathway Commons Protein-Protein Interactions	1.0	null
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.22617
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.0358
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924276
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ARID5B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852522
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869725
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924741
Floral meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
FOSL2	Pathway Commons Protein-Protein Interactions	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF483	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16355
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAP3K5	Pathway Commons Protein-Protein Interactions	1.0	null
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
Ocular hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6288
FRMD6	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH661	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8272
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53444
FAM117B	Pathway Commons Protein-Protein Interactions	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.536
FAM83G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12199
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06272
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT20	CCLE Cell Line Gene CNV Profiles	1.0	2.5102
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23017
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16175
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DENND6B	Pathway Commons Protein-Protein Interactions	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
MPPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59246
FASTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20835
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57889
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7745_KD_RRP6/DIS3_SRP062389	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.37809
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910791
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37043
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964184
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1501
HCC1395	DepMap CRISPR Gene Dependency	1.0	2.65044
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52007
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37186
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20266
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	2.4116
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV3	Pathway Commons Protein-Protein Interactions	1.0	null
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51119
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53834
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18303
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60777
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.802
SFMBT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1161
PMC9391581-mmc4.xlsx-KLF4_K409Q_vs_GFP-activated-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73738
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13953
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87964
AJAP1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47277
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.69183
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873686
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82192
single-organism transport	GO Biological Process Annotations 2015	1.0	null
FOXL2NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52779
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.0423
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15489
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07178
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44777
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
DHX58	Pathway Commons Protein-Protein Interactions	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11393
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01236
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64367
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40609
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
furan	CTD Gene-Chemical Interactions	1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6882
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45079
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03568
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03719
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92785
Hemorrhage	CTD Gene-Disease Associations	1.0	1.0189
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29737
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14853
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03153
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4997
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07546
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D502MG	DepMap CRISPR Gene Dependency	1.0	11.0507
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25794
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955519
MDAMB415	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39828
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051243
ZNF90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89788
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36399
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	2.0332
NCIH2286	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54325
FADU	CCLE Cell Line Gene CNV Profiles	1.0	1.74138
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.4379
PHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51546
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3679
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950811
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03568
JUN	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16467
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63255
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05533
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960917
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-11A-12R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66796
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IM95	DepMap CRISPR Gene Dependency	1.0	2.95082
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942865
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71501
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-11A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM12	CCLE Cell Line Gene Expression Profiles	1.0	1.73716
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31785
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
ZNF324	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93555
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.63652
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3947
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40817
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24261
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1965
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.00327
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05607
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32429
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919057
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67679
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998774
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43983
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17946
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.396
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52007
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
NXT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45207
DSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60181
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GLTSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	6.5287
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974641
CHDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68716
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03419
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
MIB1	Pathway Commons Protein-Protein Interactions	1.0	null
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15608
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881944
SIPA1L3	Pathway Commons Protein-Protein Interactions	1.0	null
KIAA2026	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
ST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93631
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13957
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11094
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0735
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
BT-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1021
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53494
periventricular stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15082
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.860048
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86677
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75995
TLCD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96082
anion binding	GO Molecular Function Annotations 2015	1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38692
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34006
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
USP48	Pathway Commons Protein-Protein Interactions	1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12181
SHANK2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39379
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ALPK3	Pathway Commons Protein-Protein Interactions	1.0	null
SLC38A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54366
TMPRSS11A	Pathway Commons Protein-Protein Interactions	1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
adipose tissue	HPA Tissue Gene Expression Profiles	-1.0	-1.05751
NCOR2	Pathway Commons Protein-Protein Interactions	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.578
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04158
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
NCIH2126	CCLE Cell Line Gene Expression Profiles	1.0	1.63878
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
monocarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76629
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28324
TAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79062
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24307
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.44749
BACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6649
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834633
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05114
RH18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78234
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02993
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09002
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35483
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
ZNF365	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67613
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873092
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
OCUM1	CCLE Cell Line Gene Expression Profiles	1.0	1.91771
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
BAZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7048
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04418
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0141
retinoic acid binding	GO Molecular Function Annotations 2025	1.0	null
XKRX	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853881
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5476
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99049
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28776
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13581
LUZP1	Pathway Commons Protein-Protein Interactions	1.0	null
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93047
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-STAT4_mod_STAT4	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.28027
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04458
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862994
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71238
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.997924
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
SMC3	ENCODE Transcription Factor Targets	1.0	null
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
SIRT6	ENCODE Transcription Factor Targets	1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.124
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
DACT1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04414
SHE	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07471
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06761
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34532
TATDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1014
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26544
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22317
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52806
RV16_0Hour-B2B_None_GSE28904	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66797
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884936
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Septic Shock_Whole blood_GSE9692	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48045
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6589
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900702
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30986
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.639074
RCHACV	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92696
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	0.986705
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8231
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01437
GATA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28351
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35967
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0598
CAMSAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61598
Corneal structure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.12218
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828766
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79454
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5955
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3889
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52333
ZNF91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65212
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.61181
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-RUNX3_mod_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7006
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15837
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56201
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02014
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68259
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
Respiratory mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93835
Inflammation	CTD Gene-Disease Associations	1.0	1.10977
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
786O	DepMap CRISPR Gene Dependency	1.0	2.50617
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53975
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A172	DepMap CRISPR Gene Dependency	1.0	7.73427
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8908
IGSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37193
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85229
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82093
GSE149075_3_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00968
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81647
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5304
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
PSMA3	Pathway Commons Protein-Protein Interactions	1.0	null
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86427
GTEX-TSE9-0626-SM-3DB8B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36185
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08939
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72268
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_downregulated_RRHO_list-CREB1_opposite_genes_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GIMEN	DepMap CRISPR Gene Dependency	1.0	2.04387
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946719
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0848
A_CA_04_2009_7dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64903
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964184
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07652
NCIH446	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50076
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28843
KCNG3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193258,GSE193259_5_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21207
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15795
SARS-CoV_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.16368
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.09138
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30929
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	9.98258
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
SNU840	DepMap CRISPR Gene Dependency	1.0	3.85406
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65949
K562	DepMap CRISPR Gene Dependency	1.0	4.86111
Central corneal thickness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.55229
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90139
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882227
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14952
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38787
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02541
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74218
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46704
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14911
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998774
DNAJB12	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13357
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65349
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940926
ZNF446	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6775
ion binding	GO Molecular Function Annotations 2015	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910161
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394197
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0191
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62098
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
APH1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46543
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4649
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41345
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0334
RAB11FIP5	Pathway Commons Protein-Protein Interactions	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9185
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06496
BAHCC1	Pathway Commons Protein-Protein Interactions	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35778
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96518
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07205
NPR1	Pathway Commons Protein-Protein Interactions	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51289
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82457
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08828
TRABD2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997221
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3151
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.833095
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79959
TIMM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35715
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52761
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35786
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29632
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59066
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23814
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937627
extracellular region	GO Cellular Component Annotations 2015	1.0	null
ZFHX3	Pathway Commons Protein-Protein Interactions	1.0	null
PRKAR1B	Pathway Commons Protein-Protein Interactions	1.0	null
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
PECAPJ15	DepMap CRISPR Gene Dependency	1.0	8.38648
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92287
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46793
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10004
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43862
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8982
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03855
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAG1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10323
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43449
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94652
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472315
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.30116
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0484
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_01_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.28107
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61757
RIMS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34418
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51087
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.83621
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.870968
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31224
organic acid binding	GO Molecular Function Annotations 2015	1.0	null
SBNO2	Pathway Commons Protein-Protein Interactions	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03198
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18583
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02475
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.81698
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59968
CSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CSNK1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72317
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04321
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3465
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52737
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06998
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5233
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998774
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17655
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9382
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3396
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42705
UBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23788
SUPT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.64524
PADI2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	6.67594
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
ANLN	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30919
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87699
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965385
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04275
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88537
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47197
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96251
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943972
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PPP4R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80306
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.621
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30721
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40315
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01386
MV411	DepMap CRISPR Gene Dependency	1.0	2.16238
XYLT1	Pathway Commons Protein-Protein Interactions	1.0	null
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07183
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0245
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55946
HCFC2	Pathway Commons Protein-Protein Interactions	1.0	null
TIMM10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03412
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.06818
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21689
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.973829
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09739
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23699
MCTP2	Pathway Commons Protein-Protein Interactions	1.0	null
ERVV-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63292
Learning Disorders	CTD Gene-Disease Associations	1.0	1.35213
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
AP4B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892379
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXOSC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.304
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
lipid binding	GO Molecular Function Annotations 2015	1.0	null
L-1236	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.2703
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07194
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59349
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_420_KD_FOXM1_SRP239534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.98399
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03451
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
SMC6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13969
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42274
CROCC	Pathway Commons Protein-Protein Interactions	1.0	null
MRGBP	Pathway Commons Protein-Protein Interactions	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95341
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97439
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85443
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96708
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03358
CYBA	Pathway Commons Protein-Protein Interactions	1.0	null
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29114
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38454
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6443
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38638
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
LIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57714
GATA3	ENCODE Transcription Factor Targets	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRPM1	Pathway Commons Protein-Protein Interactions	1.0	null
EPC1	Pathway Commons Protein-Protein Interactions	1.0	null
NAV3	Pathway Commons Protein-Protein Interactions	1.0	null
PPIP5K2	Pathway Commons Protein-Protein Interactions	1.0	null
retinoid binding	GO Molecular Function Annotations 2025	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37723
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
chr9_136966624_C_G_b38	GTEx eQTL 2025	1.0	4.07037
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938852
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6865
Calycin-like	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962934
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3782
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85894
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10254
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93528
GSE103297_1_v_0_glis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.16345
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PLOD2	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4121
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35252
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986293
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39877
CTR9	Pathway Commons Protein-Protein Interactions	1.0	null
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11277
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
Lung adenocarcinoma_LUAD_TCGA-67-3774-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54587
FUOV1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93783
EW-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
SKLU-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03978
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.9228
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74363
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF484	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52511
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01809
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51008
Acute Myeloid Leukemia_LAML_TCGA-AB-2845-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIRA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.25662
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
SPG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73123
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
19597962-Table2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28348
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.3619
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09119
SUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95858
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.60501
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01057
LBX2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04961
LGALS1	Pathway Commons Protein-Protein Interactions	1.0	null
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.70545
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845515
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58562
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07909
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94303
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.746914
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88834
RUNX1	ChEA Transcription Factor Targets	1.0	null
RMGI	DepMap CRISPR Gene Dependency	1.0	3.51711
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0732
CES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41812
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62092
RFX7	Pathway Commons Protein-Protein Interactions	1.0	null
NCOA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4769
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
monocarboxylic acid binding	GO Molecular Function Annotations 2015	1.0	null
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89077
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60855
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47416
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.1783
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48325
COLO775	CCLE Cell Line Gene CNV Profiles	1.0	1.33818
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.066
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82319
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915084
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.831318
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20026
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56183
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0107
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
DHCR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85564
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828581
NCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937669
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.01625
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85971
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.81698
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35214
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44296
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
C2orf16	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18245
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876982
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944605
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.855554
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67598
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63085
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920242
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0082
HUT102	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5195
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59231
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15089
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6878
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29146
PML	Pathway Commons Protein-Protein Interactions	1.0	null
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
GEMIN5	Pathway Commons Protein-Protein Interactions	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67957
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.06952
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23814
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85512
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NH12	DepMap CRISPR Gene Dependency	1.0	2.91081
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56579
LRF	MotifMap Predicted Transcription Factor Targets	1.0	null
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24853
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53095
PHGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1751
UBE2S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00151
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32287
A498	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38292
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
CYB5D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96507
spleen_3d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02058
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55175
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92095
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61176
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937669
KYSE70	CCLE Cell Line Gene Expression Profiles	1.0	1.40611
HPAC	CCLE Cell Line Gene Expression Profiles	1.0	2.15687
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.850555
CAPN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16955
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0266
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ACACA	Pathway Commons Protein-Protein Interactions	1.0	null
Breast abscess	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88493
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87871
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66264
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15994
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33433
TAF2	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100504_TCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37034
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.2444
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	1.43097
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36332
retinoic acid binding	GO Molecular Function Annotations 2015	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.73489
TMED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6597
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0938
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17824
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36136
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79227
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0922	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902428
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2072
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54196
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4636
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08718
LOX	Pathway Commons Protein-Protein Interactions	1.0	null
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24827
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.4439
Leaf vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.673
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
chr9_136954236_C_T_b38	GTEx eQTL 2025	1.0	1.58563
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06689
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32581
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Growth Disorders	CTD Gene-Disease Associations	1.0	1.02188
RFX5	ENCODE Transcription Factor Targets	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
PHF20	Pathway Commons Protein-Protein Interactions	1.0	null
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7997
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31301
CEP55	Pathway Commons Protein-Protein Interactions	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.80563
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.16076
ECGI10	DepMap CRISPR Gene Dependency	1.0	2.94608
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827406
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.85469
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
TEX2	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
appendices_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01066
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
DIRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50969
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19205
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61691
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40058
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841117
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42377
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37996
PRKCDBP	Pathway Commons Protein-Protein Interactions	1.0	null
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07103
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
TNFRSF18	Pathway Commons Protein-Protein Interactions	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.35328
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5855
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-TBX21_mod_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03804
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.431
GULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25546
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888472
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96479
JHU011	DepMap CRISPR Gene Dependency	1.0	2.29739
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36108
Perturb_430_KD_FOXM1_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.98399
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47336
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.70954
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920964
CARNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79548
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15994
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79204
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07099
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3376
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71245
B3GNT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61033
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29588
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01691
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60918
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72219
PRRC2A	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF740	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72012
FOXA1	ENCODE Transcription Factor Targets	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-1.03437
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.31867
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS27L	Pathway Commons Protein-Protein Interactions	1.0	null
BCLAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91938
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874712
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.598
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
RAD21	ENCODE Transcription Factor Targets	1.0	null
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.43353
QPCTL	Pathway Commons Protein-Protein Interactions	1.0	null
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28769
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.865569
MUC3A	Pathway Commons Protein-Protein Interactions	1.0	null
SELENOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92263
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998546
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06933
GSE131649_4_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterior polymorphous corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22355
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15691
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
CLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69113
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
JUN	ENCODE Transcription Factor Targets	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86677
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57256
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74009
p1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30198
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02248
chr9_136952637_G_C_b38	GTEx eQTL 2025	1.0	3.59964
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878288
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25683
Transport of fatty acids	Reactome Pathways 2014	1.0	null
ITGAL	Pathway Commons Protein-Protein Interactions	1.0	null
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955833
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921808
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40676
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43192
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58365
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31665
FOXC2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11938024-ADMA-37-2413413-s001.xlsx-Table_S1a_DE_Genes_analysis-Table_S1a_Differentailly_expressed_genes_Control_vs_NPs_treated_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
MED12L	Pathway Commons Protein-Protein Interactions	1.0	null
RALGAPA1	Pathway Commons Protein-Protein Interactions	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.11578
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01245
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07947
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40468
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AGPAT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31304
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1114
VAC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53464
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0445
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857231
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85154
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837293
Hypertrophy	CTD Gene-Disease Associations	1.0	1.65864
lipid transport	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85878
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67679
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.33533
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79321
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
MYO18A	Pathway Commons Protein-Protein Interactions	1.0	null
Visual areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1587
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959392
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72202
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08831
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850217
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24443
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01657
Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02137
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50736
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86811
BRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79762
ZNF106	Pathway Commons Protein-Protein Interactions	1.0	null
chr9_136961072_T_C_b38	GTEx eQTL 2025	1.0	1.55648
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56103
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
CACNA1G	Pathway Commons Protein-Protein Interactions	1.0	null
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72399
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41258
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23532
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBFA	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24793
USP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92254
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.65831
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
MATN4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14027
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08478
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-RUNX3_mod_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15985
ion transport	GO Biological Process Annotations 2015	1.0	null
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43359
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06483
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.08861
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23875
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2757
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43408
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943668
disease	GWASdb SNP-Disease Associations	1.0	0.036554
Perturb_11277_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.44776
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08731
BICR22	CCLE Cell Line Gene CNV Profiles	1.0	1.35974
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08394
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920549
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3315
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3669
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4083
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2762
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31023
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.29939
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00867
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94171
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06133
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15456
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830415
S117	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88758
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892204
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997231
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02604
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	3.40792
ZC3H7B	Pathway Commons Protein-Protein Interactions	1.0	null
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982461
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93219
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886768
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70678
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23692
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IRF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4221
retinoid binding	GO Molecular Function Annotations 2015	1.0	null
ARID4B	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.18824
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33294
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86524
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3622
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86114
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93982
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39825
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_downregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
ABCA9	Pathway Commons Protein-Protein Interactions	1.0	null
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16492
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49112
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25469
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92439
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41416
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Actin cap	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
AHNAK2	Pathway Commons Protein-Protein Interactions	1.0	null
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81978
USF1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79241
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.53836
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88648
HCC515	DepMap CRISPR Gene Dependency	1.0	6.42478
ALG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80268
FZR1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5737-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0548
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837333
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.06111
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97142
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30667
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0731
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0656
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87484
SETX	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00514
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00519
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
GABRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99516
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39381
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826914
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68866
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09505
PRR11	Pathway Commons Protein-Protein Interactions	1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44994
WIPF1	Pathway Commons Protein-Protein Interactions	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.70413
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989684
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4465
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16853
TRMT10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	5.17959
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9499
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
ZC3H18	Pathway Commons Protein-Protein Interactions	1.0	null
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38168
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.01549
OAW28	CCLE Cell Line Gene Expression Profiles	1.0	1.37332
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37986
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01679
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
metabolic process	GO Biological Process Annotations 2015	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913361
MAST4	Pathway Commons Protein-Protein Interactions	1.0	null
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08219
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15237
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18035
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retinoid binding	GO Molecular Function Annotations 2023	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C20orf57	Pathway Commons Protein-Protein Interactions	1.0	null
Transport of vitamins, nucleosides, and related molecules	Reactome Pathways 2024	1.0	null
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.30116
ARHGAP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58979
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2167
UNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3797
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.56738
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	1.96713
GTEx Thyroid 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	5.2368
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858228
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62376
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859264
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23857
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84613
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34317
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18871
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.75494
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9092
SLC25A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67744
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32191
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.746689
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB6	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99743
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96518
MAFK	ENCODE Transcription Factor Targets	1.0	null
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5799
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06452
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
PSMC1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPZ_02_05	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5961
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2027
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15308
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20113
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90969
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.800389
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52319
HIST1H2AB	Pathway Commons Protein-Protein Interactions	1.0	null
LRP1B	Pathway Commons Protein-Protein Interactions	1.0	null
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08879
Floral primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Hepa-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07747
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20235
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17589
GSE196343_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH3PXD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2961
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41091
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16692
ARID3A	ENCODE Transcription Factor Targets	1.0	null
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30203
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72621
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958875
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61647
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
NCIH684	CCLE Cell Line Gene Expression Profiles	1.0	1.36273
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-KLF16_KLF16	Rummagene Transcription Factor Associations 2026	1.0	null
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
TNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58718
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.35792
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01591
MAFG_02_189	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73039
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18064
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
RPS21	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11887
TENC1	Pathway Commons Protein-Protein Interactions	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62309
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01757
transverse gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47794
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44082
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49972
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.5203
POP4	Pathway Commons Protein-Protein Interactions	1.0	null
SKNBE2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70115
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.285
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06532
POU3F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85117
ESR1_T47D_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973583
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59519
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8276
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24643
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47215
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00121
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46822
MTRF1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57374
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09082
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88545
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998567
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
IL1B	Pathway Commons Protein-Protein Interactions	1.0	null
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
PE/CA-PJ15	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00316
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3868
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83721
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33627
U2AF1_02_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
KLHDC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55611
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	7.09486
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61421
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11663170-125_2024_6286_MOESM1_ESM.pdf-9-HEY2_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52389
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87056
HCC70	DepMap CRISPR Gene Dependency	1.0	4.37511
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929278
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34049
EFO21	CCLE Cell Line Gene Expression Profiles	1.0	1.44804
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2739
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
HDGFL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45667
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
GATA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18698
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23113
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.0062
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
MAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95161
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940661
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.396
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIP2B	Pathway Commons Protein-Protein Interactions	1.0	null
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23432
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
FASTKD1	Pathway Commons Protein-Protein Interactions	1.0	null
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0626-SM-2S1PP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87366
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62214
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913667
BORCS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5594
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891893
Lung adenocarcinoma_LUAD_TCGA-55-8092-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43843
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42719
Perturb_12523_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A781-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14438
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.1491
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.44097
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.329
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856586
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69931
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30529
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57037
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23775
EWSR1_02_167	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61078
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27232
NPTX2	Pathway Commons Protein-Protein Interactions	1.0	null
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37464
ZNF829	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49497
LGALS7B	Pathway Commons Protein-Protein Interactions	1.0	null
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859801
RERFLCAI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.40038
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49674
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83047
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75882
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
MFE280	CCLE Cell Line Gene Expression Profiles	1.0	1.59298
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15751
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06532
Extratemporal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992184
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11887
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVISE	CCLE Cell Line Gene Expression Profiles	1.0	2.00092
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27284
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2992
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836285
CALD1	Pathway Commons Protein-Protein Interactions	1.0	null
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
PJA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NOMO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55009
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38528
TSKU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03604
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899951
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864774
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051396
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04574
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742
UBTF	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0268
CHCHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77288
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Corneal ectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.1358
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16175
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6768
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247764_0_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98945
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01982
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31806
NFIL3	Pathway Commons Protein-Protein Interactions	1.0	null
Heschl's gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11749
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14009
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15386
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30658
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAMD9L	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
CAL62	DepMap CRISPR Gene Dependency	1.0	2.13397
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842347
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.85675
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37829
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.608
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71659
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51125
SUCLG2	Pathway Commons Protein-Protein Interactions	1.0	null
NR3C1	ENCODE Transcription Factor Targets	1.0	null
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01236
LMNA_02_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
Plume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7194
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
BPTF	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72882
TENM2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
GSE145990_1_v_5_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3953
WM793	CCLE Cell Line Gene Expression Profiles	-1.0	-2.51342
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20787
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF354B	Pathway Commons Protein-Protein Interactions	1.0	null
FERMT3	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92095
ATPAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60504
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82457
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54239
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895271
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05472
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15415
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50884
occipito-temporal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13409
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.797
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72714
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17838
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.965696
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.790182
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30309
L1236	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32879
DDX51	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05645
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34166
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
ZNF790	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54608
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826309
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33114
MAX	ENCODE Transcription Factor Targets	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75G-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24914
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8669
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56383
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1391
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07274
RRP1B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971954
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27187
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40539
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24723
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26597
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4337
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976385
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75574
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29555
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15582
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84577
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11505
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
TSSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98452
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
abnormality of circulating hormone level	GWASdb SNP-Phenotype Associations	1.0	1.90864
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49021
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51222
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940861
SSNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18739
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	0.999475
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.90268
ACTC1	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07747
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06686
HOXA10	Pathway Commons Protein-Protein Interactions	1.0	null
TDG	Pathway Commons Protein-Protein Interactions	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.46436
USP36	Pathway Commons Protein-Protein Interactions	1.0	null
UQCRFS1	Pathway Commons Protein-Protein Interactions	1.0	null
KLF10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
CHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37094
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
ARG1	Pathway Commons Protein-Protein Interactions	1.0	null
CTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
SJSA1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77153
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51661
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2176
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96518
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00798
SF1_01_271	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.76789
USP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86281
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86258
DYNLRB1	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58977
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
NT5C3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95497
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16431
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74288
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Subgeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27303
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976603
ZNF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54565
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22075
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63399
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.035
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.05481
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21423
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Airway fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
CCM2L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74104
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9643
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01587
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02139
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05329
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0947
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6622
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86303
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92731
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996419
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
CAS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87137
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17983
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03859
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85605
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10878
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18601
LMNB2_02_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.70044
Hmgn1_KO_GDS5010_407_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.727
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04347
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7413
Lung adenocarcinoma_LUAD_TCGA-55-8615-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869635
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.913
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	1.72223
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64495
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12019
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IC-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFHAS1	Pathway Commons Protein-Protein Interactions	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7193
HK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53593
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830884
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75714
DEPDC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00112
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2126
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69717
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850603
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
C4A	Pathway Commons Protein-Protein Interactions	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39389
ARFGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19004
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09829
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29257
PPIF_KO_GSE23028_45_mouse_heart (8 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2873
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56171
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65482
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00491
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49846
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905313
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2395
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898019
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25357
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57756
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2449
ELFN1	Pathway Commons Protein-Protein Interactions	1.0	null
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84526
CPSF2	Pathway Commons Protein-Protein Interactions	1.0	null
STARD3NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
RCM1	CCLE Cell Line Gene Expression Profiles	1.0	2.00632
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.722
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16258
KALRN	Pathway Commons Protein-Protein Interactions	1.0	null
SNU719	CCLE Cell Line Gene Expression Profiles	1.0	1.82318
MUC5AC	Pathway Commons Protein-Protein Interactions	1.0	null
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
SYNE1	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09432
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
RPP30	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
CYP2U1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870702
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5329
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01975
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839786
PMC6545035-12943_2019_1031_MOESM7_ESM.xlsx-Sheet1-Supplementary_table_5_The_significant_reduced_genes_in_TET1_knockdown_cells_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCA1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931358
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26678
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89463
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68257
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38279
ABCB1	Pathway Commons Protein-Protein Interactions	1.0	null
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55722
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959163
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.771756
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93553
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8805
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62058
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Transport of fatty acids	Reactome Pathways 2024	1.0	null
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43534
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22482
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5675
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.35974
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965975
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
AIFM2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05798
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L3MBTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2108
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04797
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23178
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5526_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WT-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58072
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49168
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996445
TAL1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47947
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19619
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
TAL1	ENCODE Transcription Factor Targets	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8908
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33169
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15497
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58324
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.847711
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36642
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4123
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20556
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99743
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TXN	Pathway Commons Protein-Protein Interactions	1.0	null
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23932
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77248
SOX9	ChEA Transcription Factor Targets	1.0	null
ULK1_knockout_197_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75027
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1958
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39248
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.03273
GGCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84393
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-TBX21_mod_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4999
PECAPJ15	CCLE Cell Line Gene CNV Profiles	1.0	2.42349
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5335
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lipocalin/cytosolic fatty-acid binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
RBM34_02_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.73697
ZNF502	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71715
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936234
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41962
all	GWASdb SNP-Phenotype Associations	1.0	0.03565
Perturb_11311_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.5164
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36908
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51681
LRCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05289
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.21468
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZZEF1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.211
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31552
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27663
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20753
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80081
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.30116
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01979
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Parenchyma of thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
CoPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15008
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8048
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1958
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97303
NOMO2	Pathway Commons Protein-Protein Interactions	1.0	null
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55337
MAP3K11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94336
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
ERBB2IP	Pathway Commons Protein-Protein Interactions	1.0	null
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72691
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28399
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4017
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11753
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01486
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_WT_KLF4-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.990139
hsa-miR-378g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38196
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36296
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16623
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.8127
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1749
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99739
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80102
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31165
GPR158	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862515
DPM1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964097
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86565
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10579
GTF2F1_02_157	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.48543
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33619
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051397
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00535
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44127
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00267
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11144
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15472
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07616
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77053
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54223
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954561
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843829
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10528
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21557
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11909
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990313
MCF2L2	Pathway Commons Protein-Protein Interactions	1.0	null
organic anion transport	GO Biological Process Annotations 2015	1.0	null
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840778
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69418
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925151
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21747
KIAA0319	Pathway Commons Protein-Protein Interactions	1.0	null
SCC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hela	HPA Cell Line Gene Expression Profiles	1.0	0.995105
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13897
TIA1_KO_GSE54418_263_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MYOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97042
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39947
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18212
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
Primary somatosensory area, mouth, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42878
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.62334
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11399
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925785
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52433
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30196
IL16	Pathway Commons Protein-Protein Interactions	1.0	null
FUOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36677
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.761167
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66205
Transport of vitamins, nucleosides, and related molecules	Reactome Pathways 2014	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50663
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53713
TPH1	Pathway Commons Protein-Protein Interactions	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC	Pathway Commons Protein-Protein Interactions	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
CHAF1B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55401
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935703
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
METRNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11368
NCI-H647	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GABRR1	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47443
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861109
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884216
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF585A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58656
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7214
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11189
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19631
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
ZNF703	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2542
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73839
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
CCK81	DepMap CRISPR Gene Dependency	1.0	2.10922
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16039
FANCM	Pathway Commons Protein-Protein Interactions	1.0	null
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78625
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15308
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05939
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92415
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4807
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9919
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48697
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
A172	CCLE Cell Line Gene CNV Profiles	1.0	1.67095
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2069
BUB1	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2069
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02358
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10871