association	dataset	threshold value	standardized value
Perturb_13923_KD_DDX5/DDX17_SRP335223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.42389
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_16815_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.61813
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perturb_8051_KD_SETD2_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.91077
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894935
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5019
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90931
Perturb_17802_KO_ZNF675_SRP305529	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01701
LMTK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63914
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5067
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
Perturb_6939_KD_EP300_SRP068733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
precuneus, left, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947653
Perturb_9106_KD_SNHG12_SRP223778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.72924
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30897
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35666
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-2.107
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14705
Perturb_9146_KD_LRRC8A_SRP306897	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.71119
Perturb_5527_OE_Uprt_ERP106180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.72588
hsa-miR-3907	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9515
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2933
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_17627_KO_NF2_SRP153109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.8729
Perturb_7629_KD_UPF1_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.99299
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897915
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1741
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94175
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8263_KD_DDX52_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.26977
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0305
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36379
Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZJ-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	0.944717
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09836
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33789
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1616
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04301
Perturb_4330_KD_PTGS1_SRP055392	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05224
Perturb_3565_KD_BMI1_SRP297906	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.188
Perturb_4758_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.9134
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35288
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Perturb_15421_KD_ELL2_SRP214471	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3554
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_14599_KD_IGF2BP1_SRP252427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.184
SKMM2	DepMap CRISPR Gene Dependency	1.0	3.94579
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59162
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17806_KO_ZNF675_SRP304971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01701
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11524
Perturb_4334_OE_PIM1_SRP312314	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.77449
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_2360_KD_TSHZ3_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.83167
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN319	CCLE Cell Line Gene CNV Profiles	1.0	2.75612
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12662_KD_KPC1_SRP071659	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.30993
GTEX-XMK1-2526-SM-4B666	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03026
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_772_KD_SRRM2_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46332
Perturb_10105_KD_DDX3X_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.75657
Perturb_10031_KD_MSI2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62583
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00002
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9100_KD_Tfpi_SRP312891	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.56663
Perturb_6621_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
Perturb_459_KD_RPLP1/RPLP2_SRP202033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.92326
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.43709
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845456
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01941
NUP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18627
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02837
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849505
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12366_KD_SLC39A7_SRP274341	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.4717
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.6021
Perturb_2779_OE_ACF7_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.6273
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16404
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8726
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58448
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09961
Perturb_3936_KD_MIR1290_SRP291996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.38808
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12793
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17049
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929181
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863098
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838966
Perturb_12026_OE_ID1_SRP333901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3061
Perturb_414_KO_PAF1_ERP136917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.49379
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75201
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963827
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.06455
Perturb_16789_OE_EHF_SRP309336	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.56649
Perturb_7756_KD_DIS3_SRP337423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.02566
MVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62731
Perturb_14160_KD_IPO11_SRP316321	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.71627
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39196
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74484
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825099
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4904_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59523
Perturb_5393_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85662
Perturb_6618_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7249
Perturb_12027_OE_ID2_SRP333901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_7704_KD_YTHDF1_SRP214946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.44029
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26623
Perturb_540_OE_EWS/FLI_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.75134
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07436
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02145
hsa-miR-4763-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIFBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41892
Perturb_8449_KD_LETN_SRP230777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02435
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AHSA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51826
RUNX1	ChEA Transcription Factor Targets	1.0	null
Perturb_12138_KD_OTX2_SRP347033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.3259
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_551_KD_EWSR1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.92683
Perturb_5466_KD_WWTR1_SRP125175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.73809
Perturb_8091_KD_NOL12_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.92962
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
hsa-miR-1914	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38688
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-519e	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Perturb_7314_KO|KD_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.46116
Perturb_598_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
IRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06143
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_11530_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0532
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-1434_proliferation_genes-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2665
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58844
Perturb_8126_KD_AKAP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.15792
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
Perturb_12159_OE_TCF7_SRP144189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.95153
Perturb_2717_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.7066
Perturb_5654_KD_FLI1_SRP117628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55577
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28101
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48373
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10583
Perturb_10153_KO_ARID4B_SRP255645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.34751
Perturb_6481_KD_SERBP1_ERP118886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.10959
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66247
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.88637
Perturb_8239_KD_RECQL_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.07362
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2105_KD_DHX8_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.15519
Perturb_9964_KD_NSUN2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.46361
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7084
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32026
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Perturb_525_KD_TLR3/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.375
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
Perturb_11407_KD_HNRNPM_SRP143499	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.98799
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_14588_KD_TCF7L1_SRP094619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.89217
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
Perturb_9943_KD_PUS1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.53968
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938408
Perturb_12108_KD_CCND1_SRP244245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.7689
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56561
Perturb_2090_KD_H2AZ1_SRP199103	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.17952
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40963
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98708
Perturb_3866_KD_MEF2D_SRP333146	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.7535
hsa-miR-1269	TargetScan Predicted Conserved microRNA Targets	1.0	0.009975
Lung squamous cell carcinoma_LUSC_TCGA-77-8130-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
hsa-miR-4322	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
EBF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53906
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38642
IL17RB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00391
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_2285_OE_TLX_SRP358206	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.77264
Perturb_10093_KD_XRCC6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43734
Perturb_411_KO_PAF1_ERP136917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.17225
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05554
Perturb_7626_KD_UPF1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.99299
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82601
Perturb_18448_KD_PHF14_SRP199105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.0997
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17118
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7637_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.22721
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90429
GTEX-UPIC-0326-SM-4IHJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20869
JHH7	DepMap CRISPR Gene Dependency	1.0	2.66305
Perturb_6460_KO_EZH2_SRP136292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60929
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28998
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_6833_KD_CASC9_SRP182039	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.70819
Perturb_8225_KD_DKC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0651
ADAM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24819
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7811_KD_MTREX_SRP091999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.49745
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.34975
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890114
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0188
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.808
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OHPL-3026-SM-3MJGS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833974
Perturb_17530_KO_TET1_SRP150212	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.01835
Perturb_7597_KO_TENT3A/TENT3B_SRP400572	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.1103
Perturb_9758_OE_Mbnl1_SRP354130	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.21235
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1935
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30046
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.917055
Perturb_10112_KD_FXR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45437
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.861033
Perturb_12952_KO_ZFP36L2_SRP251843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49845
Perturb_14286_OE_YAPS94A_SRP336792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827028
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_499_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.89355
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81237
Perturb_13683_KD_FTO_SRP116935	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.01468
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0836
Perturb_12742_KD_GOT1_SRP282058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.91806
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11839
brain	HPA Tissue Gene Expression Profiles	-1.0	-1.18867
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07447
Perturb_9649_KD_T208_SRP327946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.71687
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25664
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_2464_KD_SETDB1_SRP344480	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.08942
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54076
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56376
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90004
Perturb_9997_KD_SMN1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.628
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.82089
RBM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29087
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12858
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21733
TC205	DepMap CRISPR Gene Dependency	1.0	2.94949
transverse gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22145
Perturb_1095_KO_ATXN1L_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04557
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_410_KO_IRE1_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.5568
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43176
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2987_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44991
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2985_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.93297
HH	CCLE Cell Line Gene CNV Profiles	1.0	1.53557
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3451
hsa-miR-378h	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.62558
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930777
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
Perturb_12348_KD_BRCA1_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.63719
Perturb_597_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46228
Perturb_347_KO_BIRC2_SRP222904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.28025
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39215
Perturb_9970_KD_WDR43_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08266
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2724_KD_ZNF148_SRP201806	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.73482
Perturb_15214_KD_KLF4_SRP255722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90114
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPT6-0326-SM-4B66V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52552
Perturb_8191_KD_ILF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.4407
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MINDY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99218
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
U87MG	DepMap CRISPR Gene Dependency	1.0	3.66603
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2379
Perturb_8813_KD_YAP1/WWTR1_SRP284279	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.6357
Perturb_11688_KD_RRM2|CDKN2A_SRP212736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5063
Perturb_1350_KD_NSUN2_SRP212699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.711381
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7457_KO_DHX36_SRP120502	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.29102
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31733
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87157
Perturb_524_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.48247
Perturb_8100_KD_ABCF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.67053
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_14285_OE_YAPS127A_SRP336792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
STAT6_01_50	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.77561
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14361
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19759
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859422
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.33265
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE200839,GSE233826_2_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2064_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.60565
Perturb_2745_KD_EMP2_SRP215373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.47711
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8196_KD_TIAL1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.82725
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38556
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47824
496100332_HIP_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56805
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_10139_KO_DCAF15_SRP214323	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.42318
Peritoneal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
Perturb_2384_KO_ASXL1_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.1554
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74579
LRFN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51812
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.24805
Perturb_8320_KD_ARID1A_SRP059066	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28747
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-330-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40124
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1094_KO_ATXN1L_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20674
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907455
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43159
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
Perturb_2300_KD_BRCA1_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49503
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2284_OE_TLX_SRP358206	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827807
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5489
Perturb_15867_KD_KDM3A_SRP248023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.23095
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31096
Perturb_14407_KD_PGK1_SRP252531	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.73505
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898239
hsa-miR-1299	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29816
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.23845
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07165
temporal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24264
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50836
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13289
Perturb_3573_KD_JAB1_SRP222371	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_8282_KD_BCCIP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.05244
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.301
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12623_KD_MITF_SRP150609	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.26615
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999044
Perturb_537_KD_MYBL2_SRP161768	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95491
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-4656	TargetScan Predicted Conserved microRNA Targets	1.0	0.029271
Perturb_4859_KD_BCOR_SRP119523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.7161
Perturb_8102_KD_BUD13_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47172
Perturb_9130_KD_PHGDH_ERP020769	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.25937
Perturb_4863_KD_BAF47_SRP188516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0557
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53311
Perturb_2371_KO_TET2_SRP163132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.9902
Perturb_7743_KD_RRP6/DIS3_SRP337423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.76907
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
Perturb_8340_OE_PCBP2_SRP219036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9519
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8163_KD_SRSF3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.21861
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35975
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_2617_KO_RB1_SRP252396	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.9869
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98255
km3	HPA Cell Line Gene Expression Profiles	1.0	1.04153
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840766
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17318
Perturb_10114_KD_NCBP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67713
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02192
Perturb_3693_KO_GPX8_SRP353993	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.0757
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62872
Perturb_13949_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.75386
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03605
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWN1-2026-SM-48TD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19703
Perturb_6308_KD_PUM1_SRP396076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.1004
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05236
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18518
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14572_KO_EP300_SRP336466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.76156
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
Perturb_8918_KD_ARID1A_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.68232
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
MTHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16544
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3256
Perturb_9174_KD_WTAP_SRP238262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.23431
Perturb_10166_KD_ENL_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.71784
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
Perturb_5550_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57513
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998733
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PNMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73836
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Perturb_7950_KO_BAZ1A_SRP100570	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.15808
Penis_Foreskin_Keratinocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.09634
TTC549	DepMap CRISPR Gene Dependency	1.0	3.62435
Perturb_9118_KO_PCK2_ERP116055	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.3904
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78086
Perturb_8368_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.75467
Perturb_11962_KO_Tr1_SRP355815	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16762
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41812
KYSE410	DepMap CRISPR Gene Dependency	1.0	2.60036
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904464
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
APOBEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49151
Perturb_2343_KD_KRT5_SRP342396	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.40604
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32327
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843432
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1167
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964999
hsa-miR-4741	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58949
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2576
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34596
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852841
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841203
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
G-402	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.06736
Perturb_8445_OE_GSTZ1_SRP155565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.20919
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3845_KD_lncRNAAF339830_SRP161584	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.65988
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5306
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98545
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05261
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17344
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82243
Perturb_7911_KO_LIN52_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.80246
Perturb_9710_KD_SMARCB1_SRP279089	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx Colon 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.0912
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12431
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61366
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04282
hsa-miR-9	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_5553_OE_BAHD1_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.1297
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
Perturb_13886_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0602
Perturb_9627_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.50931
Perturb_3915_KD_CTNNB1_DRP003300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.238
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24654
Perturb_230_KD_HIF1A_SRP100624	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.41821
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.89651
FZD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87386
Perturb_7645_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.49167
Perturb_2065_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.28143
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857671
Perturb_9931_KD_TRA2A_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.12598
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2327_KD_SF3B3_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.5926
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
Perturb_7248_KO_LEF1_ERP109990	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.73385
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46497
Perturb_3646_KO_HDAC1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.25502
Perturb_12314_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18655
Perturb_71_KD_LINE1_ERP011233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10702
Perturb_13682_KD_METTL14_SRP103115	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.60864
GTEX-VJWN-0626-SM-3NMAN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04577
Perturb_7923_KD_EXOSC3_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.03612
Perturb_6292_KD_CBSLR_SRP145485	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.51006
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33076
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.67139
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC12	DepMap CRISPR Gene Dependency	1.0	3.65583
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00371
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47012
Perturb_13021_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.21984
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48735
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9687
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49267
Perturb_8919_KD_ARID1A/P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.3136
Perturb_432_KD_RPAP3_DRP004966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.37289
Perturb_282_KD_IMPDH1_SRP251285	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.9694
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84893
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891816
hsa-miR-378g	TargetScan Predicted Conserved microRNA Targets	1.0	0.006367
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8805_KD_PTB_SRP069229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.38971
Perturb_10002_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.45402
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23524
Perturb_12935_KD_CDK9_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.0421
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34377
Perturb_12918_KD_C1orf186_SRP411666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.00501
Perturb_14085_KD_GAS41_SRP110132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8190_KD_HNRNPU_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.50694
Perturb_12667_OE_MX2_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.60672
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28146
Perturb_12513_KO_ERO1_ERP137480	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.45395
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15215
OVCA420	DepMap CRISPR Gene Dependency	1.0	6.58804
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8566
Perturb_15699_KD_PARP1_SRP280274	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_3639_KO_BRD3_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.2042
Perturb_7913_KO_ZNF335_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.03597
Perturb_14853_KD_TEAD4_SRP247403	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12475
Perturb_2474_OE_HER2_SRP229951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43334
Perturb_15457_KO_GPRC5A_SRP165862	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4433
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21237
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.52702
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_4855_KD_ZNF503_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.94739
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93443
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
GSE139239_3_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2148_OE_RKIP_SRP189735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.66388
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09462
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23079
GTEX-WHWD-2426-SM-3LK6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980053
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_6469_OE_PROX1_ERP110083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.3979
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_8801_KD_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.41598
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.98326
Perturb_12349_KD_BRCA2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.17275
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881332
Perturb_14878_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.53132
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4339_OE_ISL1/LHX3_SRP271657	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25945
Perturb_13604_KD_YAP1/WWTR1_SRP221804	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_12997_KO_rs2431697_ERP121303	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.04228
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19294
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89985
Thymus-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.57914
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35324
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8234_KD_NELFE_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.7205
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9838_KD_GCN2_SRP248465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.92138
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_6_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897181
PMC3605762-NIHMS50352-supplement-2.xlsx-ST12-Supplementary_Table_12_Details_of_proxy_SNPs_analysed_in_follow-up_studies_if_the_lead_SNP_was_unavailable_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922835
PACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39329
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_5429_KD_ATF3_SRP308440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.88905
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
Perturb_14098_KD_AHR_SRP154013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.00835
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
YY1	ENCODE Transcription Factor Targets	1.0	null
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33242
EJM	DepMap CRISPR Gene Dependency	1.0	4.83963
Perturb_8048_KD_METTl14_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.98061
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-1.15888
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38519
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943213
Perturb_9971_KD_BCCIP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.99303
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986485
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62764
DNAJB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99789
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.53375
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_2323_KD_RBMX_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.44261
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4264
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00406
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OGDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.757
ROS50	DepMap CRISPR Gene Dependency	1.0	3.19739
Perturb_8221_KD_ACO1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05323
Perturb_13909_KO_QPRT_SRP143388	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.98316
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PLIN5_OE_GSE44192_482_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2567
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6480_KD_SNRPB_ERP011528	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_12318_KD_NRDE2_SRP161520	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.41448
Perturb_10005_KD_METAP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47316
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.92236
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7324
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7935_KO_VTRNA1_SRP252980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.52221
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30081
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10435_KO_PPFIA1_SRP127326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36461
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862284
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76784
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41642
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
Perturb_464_KD_IGF2BP1_SRP251876	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.31464
Perturb_9835_KD_GCN2_SRP248465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.59798
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60409
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71125
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05162
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4898
Perturb_12688_KD_USP34_SRP150508	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.81247
COV413A	DepMap CRISPR Gene Dependency	1.0	2.03839
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
Perturb_15196_KD_MLXIP_SRP186292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.44693
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59693
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1728
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
Perturb_8131_KD_EIF2S1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.73165
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15521_OE_proL1_SRP277452	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.89162
Perturb_6601_KD_NFE2L2_SRP158498	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76678
Perturb_7621_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.86422
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29373
Perturb_12726_KO_MITF_SRP255094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.87387
Perturb_2071_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.07788
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18625
hsa-miR-3607-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hsa-miR-802	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_2316_KD_PRPF31_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.92263
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67957
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86055
Perturb_11960_KD_RAD6B_SRP258673	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.8239
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
fat_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.55394
Perturb_12304_KO|OE_EZH2|HOTAIR_SRP062995	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.35601
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_547_KO_SA1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.69319
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-378b	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WRHK-1726-SM-3MJFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24909
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_8273_KD_RPS19_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0115
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71306
Perturb_16813_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08328
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21211
Perturb_504_KD_METTL3_SRP039397	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.30556
Perturb_8067_KD_SNORD126_SRP337208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.03318
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4576
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14578
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.52002
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1037_Mut_C15orf48_SRP289006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.49853
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66334
Perturb_13373_KD_RPRD1B_SRP362755	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.87626
Perturb_445_KD_SORD_SRP121474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6608
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57754
Perturb_530_KD_KLF15_SRP234742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.26782
Perturb_12910_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.99869
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23999
Perturb_10018_KD_LIN28B_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.37896
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00878
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910106
Perturb_7863_KD_METTL3_SRP226173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.0925
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24412
Perturb_4852_KD_ZNF503_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.455
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.734031
Perturb_13753_KD_EP300_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.1671
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53255
Perturb_3720_KD_CHD4/DNMT1_SRP049370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.11017
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9366
Perturb_8752_KD_ANLN_SRP083014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.62212
Perturb_6706_KD_ELOA_SRP314942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.72376
CAMKK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32594
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836403
GATA2	ENCODE Transcription Factor Targets	1.0	null
RCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99096
Perturb_461_KD_HNRNPK_SRP238505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24493
SMAD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74283
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84705
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990009
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08112
CHLA57	DepMap CRISPR Gene Dependency	1.0	3.54665
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_545_KD_CT_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.26617
hsa-miR-378	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Perturb_10026_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.7543
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2484
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.8486
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3331
hsa-miR-1915	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7631_KD_AF4_SRP078067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.83616
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.01142
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845366
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61964
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20477
Perturb_10013_KD_FKBP4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.44736
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52139
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7462
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22061
Perturb_12293_OE_RORC_SRP066204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.31816
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32285
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23672
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28445
Perturb_12364_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.98286
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10878
Perturb_9986_KD_U2AF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.80945
Perturb_478_KD_PPARGC1A_SRP278736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.19993
CALU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95801
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.931317
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19809
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8368
Perturb_9099_KD_SSX_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.9714
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5208
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24594
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
Perturb_14625_KO_OGT_SRP146064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.4202
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55332
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89538
Perturb_509_KO_PAF1_ERP136917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.11526
BCPAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0932
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.91768
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25356
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965321
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848552
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38854
Perturb_8096_KD_SRSF5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.9416
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18218
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3749_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.26293
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-422a	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10098_KD_DDX47_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52026
Perturb_3750_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_5564_KO_KDM4C_SRP375293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.41326
Perturb_9936_KD_CCDC124_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.32759
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20217
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03326
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19239
Perturb_14125_KO_TP53/CDKN2A_SRP258861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96515
Perturb_3643_KO_DNMT1_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.20789
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89358
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18779
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20233
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13833_KD_RYK_SRP131789	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.8367
Perturb_2128_KD_DDX41_SRP309134	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.2791
hsa-miR-3145-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0917
Perturb_3909_KD_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43283
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947588
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.75653
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
Thymus-vein endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	3.83033
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852786
Perturb_14586_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.57909
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02145
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8267_KD_FAM120A_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.31641
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8236_KD_PTBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.71856
Perturb_16445_KO_MITF_SRP298756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.84867
Perturb_9944_KD_RBM15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.4618
GTEX-WYJK-0426-SM-3NM9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21066
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_5630_KD_EWSFLI1_SRP340258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.27773
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7982
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13296
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84461
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65635
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRD5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86574
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17937
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE153124_4_v_3_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18368
Perturb_14627_KO_OGT_SRP146064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26739
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53828
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_14253_KD_QKI_SRP272585	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09236
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1797
Perturb_11538_KD_YEATS2_SRP094447	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.699
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77405
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.79208
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881601
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05261
GTEX-XUYS-0426-SM-47JX3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76584
Perturb_9661_KD_circTTN1_SRP260174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-1269b	TargetScan Predicted Conserved microRNA Targets	1.0	0.008128
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839294
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1813
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_14126_KO_TP53/CDKN2A/PTEN_SRP258861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.86741
Perturb_13854_KD_SOX9_SRP201900	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.54183
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_15439_KD_NUSAP1_SRP074246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48102
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.9963
Perturb_8140_KD_KHSRP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.1025
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3669
Perturb_7949_Mut_BAZ1A_SRP100570	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.031
Perturb_4601_KD_CD248_SRP250350	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3806
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73868
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE215351,GSE215794_4_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_6523_KD_YTHDF2_SRP239270	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.80508
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_326_KO_CDK12_SRP334730	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2407
GSE128563_2_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_737_KD_CHD4_SRP123294	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.2411
Perturb_6616_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58627
PRR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13988
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8197_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_9857_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.82284
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40616
Perturb_8261_KD_RPS2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13699
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2696_KO_SET1B_SRP089784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.44744
GTEX-QCQG-0726-SM-48U1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937426
hsa-miR-3689d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SNU601	DepMap CRISPR Gene Dependency	1.0	5.06161
Perturb_9116_KD_SMAD6_SRP252947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.82707
Perturb_15442_KD_MED25_SRP212208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6511
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.082
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96251
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60417
Perturb_9883_KD_CPEB4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.73755
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4797-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839257
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52394
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.926713
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_15562_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.30836
YY1	ChEA Transcription Factor Targets	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	6.55767
Perturb_3633_KD_SMARCA4/ARID2_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45628
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3181
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00817
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9968_KD_UPF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.61648
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12254_KD_UGDH_SRP158392	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76873
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7204
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95221
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68409
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99538
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34493
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_5552_KO|KD_FBXO11|BAHD1_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.46698
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_36_KD_RBPJ_SRP151852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3921
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43018
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
Perturb_11404_OE_HNF1A_SRP081517	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.4416
Perturb_8055_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.37817
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
ACADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09221
MEND syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.918
Acute Myeloid Leukemia_LAML_TCGA-AB-2988-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8881_KD_CSL_SRP142324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.42905
Perturb_4876_KD_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9588
Perturb_2393_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8999
Perturb_7157_KD_NEAT1_SRP366384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.246
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73039
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67131
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74213
Perturb_11574_KO_miR375_SRP273175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.82183
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38519
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64549
Perturb_3982_KD_TIP60_SRP057708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.23497
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21672
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
GTEX-VUSG-0526-SM-4KL22	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863753
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
Perturb_15110_KD_PPHLN1_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.20481
Perturb_4760_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77914
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9289_OE_KRAS_SRP172671	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.72867
Perturb_2390_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
Perturb_3762_KO_TNFAIP3_SRP133440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95935
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_338_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.85539
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3522
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30159
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928366
Perturb_4761_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29233
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
POLR2AphosphoS2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17552_KD_YAP1_SRP372845	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.70081
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
Perturb_468_KD_ADAR2_SRP253895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6148
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04194
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5487
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10064_KD_DHX30_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15447
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.44031
Perturb_8059_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.0126
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7912_KO_RNPC3_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.68688
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70986
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88404
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914803
Perturb_14598_KD_E2F1/E2F2/E2F3_SRP252426	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-378c	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Perturb_14068_KD_ALKBH5_SRP247667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.41503
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826611
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15109_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_15441_KD_TMPOAS1_SRP273203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2595
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_13691_KD_NSD2_SRP064418	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.3688
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991521
F5	DepMap CRISPR Gene Dependency	1.0	2.10089
GTEX-RN64-0526-SM-2TC5P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06209
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7765
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08732
GB1	CCLE Cell Line Gene CNV Profiles	1.0	1.88138
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12227
Perturb_12240_KD_CHD4_SRP190500	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.45622
Perturb_6867_OE_CRLM1_SRP309080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.4698
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1344_KD_ARID1A_SRP336358	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65613
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12441
Perturb_15701_KO_BNC2_SRP327109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.91277
Perturb_10033_KD_PNPT1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.50351
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31788
Perturb_2988_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.4169
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.93291
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95692
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97984
Perturb_8998_KD_lnc Cyrano_SRP261325	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.6984
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97218
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Perturb_10127_Mut_MYB_SRP080924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2771
Primary hypoalphalipoproteinemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
Perturb_12028_OE_ID3_SRP333901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_10666_OE_HSPB2_SRP288471	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.323
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Perturb_12676_KO_PTPN2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15209
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4307
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0266
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03598
Perturb_4924_KO_RBL1/RBL2_ERP132840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.50558
Perturb_8031_KD_PURPL_SRP383476	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72859
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	5.42421
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23091
KBTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65355
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.589
PLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36402
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27209
Perturb_14764_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.95112
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
Perturb_3972_KD|Mut_SFPQ|BRAF_SRP258593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.63046
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.776582
Perturb_14840_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.56142
Perturb_9854_KD_LUC7L3_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.46395
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_3977_KD_TIP60_SRP057708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.41445
Perturb_3853_KO_NOS2_SRP325532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53395
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832615
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50626
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
Perturb_2136_KD_ARVCF_SRP186778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.77271
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05965
ZDHHC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11158
Perturb_14184_KO_KDM1A_SRP289469	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_356_KD_ERK2_SRP308190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.55616
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95841
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14929
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20354
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2856
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7755
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.950304
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	2.41483
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17717
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873056
ZNF641	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19646
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6921
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF7IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79571
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825507
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02684
Perturb_8072_KD_SNORD126_SRP337208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.91501
Perturb_9940_KD_MAK16_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.6268
GTEX-XOTO-0426-SM-4B66A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05516
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16252
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.89667
Perturb_257_KD_KLF6_SRP150445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.15961
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9166_KD_circRAB3IP_SRP366297	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.63996
Perturb_17640_OE_WWTR1_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.7052
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11536_KD_NGFR_SRP071553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55908
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.197
Perturb_8245_KD_TIA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.51327
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13476
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35089
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9669_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.35867
Perturb_15458_KD_TIP5_SRP198493	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5893
Perturb_341_KD_EGFP_SRP076553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85766
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0552
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8084_KD_CELF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.3872
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9847_KO_DCAF15_SRP214323	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.5826
Perturb_14873_KO_H11_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.82674
Perturb_6259_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.0258
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4850_KD_NKX25_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.66789
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55C-1826-SM-3GADI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37311
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8344_KD_KHSRP_SRP250831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.03558
Perturb_10172_KO_TOX4_SRP300474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.85954
SUPT11	CCLE Cell Line Gene CNV Profiles	1.0	1.97029
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52355
Perturb_6785_KD_USP42_ERP121305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.12808
Perturb_7425_KD_RBFOX2_SRP045481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.9208
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
Perturb_2478_OE_YAP_SRP254362	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.70693
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11876
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62619
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5722
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05268
Perturb_754_OE_METTL3_SRP393226	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.37327
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0426-SM-32PMF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86588
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39588
Perturb_8494_KD_U2AF1_SRP221683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05642
Perturb_10034_KD_PUF60_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.3763
hsa-miR-424	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Low-density lipoprotein (LDL) receptor class A repeat	InterPro Predicted Protein Domain Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924851
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14194_KO_ALPG_SRP277076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60188
hsa-miR-511	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
Perturb_7634_KD_DOT1L_SRP078067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.22721
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2561_KO_HSF1_SRP288220	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.53533
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940164
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05644
Perturb_8212_KD_SMNDC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.12762
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2586
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46925
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49122
SASS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5384
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27799
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8280_KD_DDX5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.26697
Perturb_2548_KO_MLL3_SRP163132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.93703
hsa-miR-497	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19048
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5348
Perturb_3142_OE_CXADR_SRP274008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.5686
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57062
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.07366
Perturb_9932_KD_AGGF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15385_KD_FGF13_SRP319157	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.32106
Perturb_16953_KO_MLX_SRP183152	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.2335
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1265
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7180_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.2528
Perturb_9937_KD_DDX19B_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.63612
Perturb_9109_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.15779
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43072
hsa-miR-4675	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40748
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861109
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78275
Perturb_7265_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.75221
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
Perturb_539_OE_EWS_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.8231
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70134
Perturb_3534_KD_KIF2C_SRP339333	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.06456
ALDH1A2_KO_GDS4836_290_mouse_anterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02645
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98915
Perturb_2873_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.21969
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42095
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988588
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25791
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24378
UOK101	DepMap CRISPR Gene Dependency	1.0	3.79958
Perturb_7043_KO_miR17/miR20a/miR92a1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76548
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4868
Perturb_8262_KD_RPS5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.53556
Perturb_101_KD_LATS_SRP353750	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.57339
MYC	ChEA Transcription Factor Targets	1.0	null
Perturb_17626_KO_CREBBP_SRP153109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9922
GSE186647,GSE217288_1_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17561
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7880_KD_INTS11_SRP266190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55488
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31271
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835044
Perturb_11949_KD_NRF2_SRP092641	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.8622
Perturb_11448_KD_PON2_SRP398037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.62556
Perturb_8804_KD_PTB_SRP069229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.61147
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15619
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01192
Perturb_14761_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24014
Perturb_2387_Mut_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.2583
Perturb_9641_KO_HES7_SRP153047	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.12748
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41354
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24063
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907705
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18509
ACTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35843
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58871
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.890109
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951053
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3606_KO_ARID2_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.35272
Perturb_10027_KD_APOBEC3C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62828
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2509
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.927252
STAT1_02_23	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62276
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	2.54205
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8189_KD_HNRNPF_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.76166
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59674
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26067
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91172
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.873471
hsa-miR-378f	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76818
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26942
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72792
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95771
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-92-PRR12_PRR12	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49431
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3649_KO_MTF2_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.34865
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3986
697	DepMap CRISPR Gene Dependency	1.0	8.8732
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88872
Perturb_7544_OE_ALPG_SRP277076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.3979
Perturb_8185_KD_DNAJC2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.20596
Perturb_8735_KD_SREBF1_SRP169608	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.82422
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4672
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7023
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_8336_KD_CTNNB1_SRP213717	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.504
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6655
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862038
Perturb_12235_KD_CHD4_SRP190500	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.7976
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04731
Perturb_14602_KD_PAR1_SRP273320	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.4018
Perturb_8230_KD_PUS1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.7395
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24257
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4558
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75193
Perturb_2277_KO_SLC35F5/SLC29A4/SLC28A3_SRP308917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46155
Perturb_7740_KO_Yap_SRP281854	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.63661
PMC3500769-srep00875-s3.xls-GATA3-Time_4_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21503
Perturb_13653_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.25298
Perturb_2053_KD_TPR_SRP217733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37324
Perturb_14055_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.10768
TSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27181
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50798
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827931
Perturb_9113_OE_FOXO1A3_SRP188991	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.09278
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88849
MAVER1	DepMap CRISPR Gene Dependency	1.0	2.43786
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.966239
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.93807
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
Perturb_8495_KD_U2AF1_SRP221683	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_289_KO_PHF8_SRP399627	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1221
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22303
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	HPA Tissue Protein Expression Profiles	1.0	0.964673
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916443
ZNF518A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01442
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14955_OE_PRDM1_SRP287780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.38911
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44459
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831544
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7349
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.12891
Perturb_95_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.94137
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931144
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35653
Perturb_8231_KD_PRPF4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.6824
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14847_KD_PEG10_SRP055517	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36289
Perturb_8848_KD_APC_SRP267478	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.779373
Perturb_17641_OE_YAP_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.9161
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.58166
Perturb_6829_KD_CDK11_SRP156201	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.4572
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28832
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00083
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.60096
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7663_KD_hnRNPC_SRP076733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.75642
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47348
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93944
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
hsa-miR-5047	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56342
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_15588_KD_SOX9_SRP355992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.27929
Perturb_9108_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.77603
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54549
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00554
CUB domain	InterPro Predicted Protein Domain Annotations	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65534
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_416_OE_CELF6_SRP341248	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.48663
Perturb_3893_KO_Lonp1_SRP301760	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.59316
Perturb_10699_KD_CD274_SRP307356	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.2834
Perturb_9935_KD_ATP5F1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.1066
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9122_KD_WTAP_SRP238262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40251
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5551_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0819
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30278
Perturb_8268_KD_GEMIN5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.90846
Perturb_14758_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.1765
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06445
Perturb_3645_KO_EP300_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71019
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9705
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6397
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41014
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11176
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28835
Perturb_17618_KO_TIP60_SRP386872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6789
Perturb_7131_KD_SETD8_DRP009168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.15976
C17orf107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32094
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.333
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19625
Perturb_12270_KD_EIF4G2_SRP149421	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.93037
MM253	DepMap CRISPR Gene Dependency	1.0	4.65755
Perturb_6678_KO_PMVK_SRP255872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81757
Perturb_2286_KO_LATS1/LATS2_SRP215870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24069
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15505_KD_CDK7_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.3786
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2786
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81065
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987268
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934463
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.19595
GTEX-WFG7-0626-SM-4LMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841843
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2618
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
Perturb_11595_KD_CGAS_SRP107235	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97566
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.825642
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922645
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25897
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02348
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35313
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27252
Peritoneum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Perturb_6420_KD_SPRY4IT1_SRP347515	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01419
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24657
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9976_KD_G3BP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.2271
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50945
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10706
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986863
NB7	DepMap CRISPR Gene Dependency	1.0	5.16462
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51418
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15127
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76725
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40279
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14185_KD_KDM1A_SRP289469	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_6445_KO_YAP_SRP134183	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.53563
Perturb_7647_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67171
Perturb_17628_KO_PTPN14_SRP153109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92402
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
METTL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3098
Perturb_14570_KO_RORC_SRP185849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.40367
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_3667_KO_FASTKD_SRP277516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.48364
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07274
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.12403
RHOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19432
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.905887
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891816
Perturb_508_KO_PAF1_ERP136917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.51938
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.31527
Perturb_10146_OE_SRSF1_SRP229734	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60365
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	2.6207
Perturb_5735_KD_NAP1L3_SRP121475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.75373
GCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49307
Brain Lower Grade Glioma_LGG_TCGA-DU-5872-02A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25085
Perturb_7600_KO_LEF1_ERP109990	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.63745
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
Perturb_12945_KD_METTL3_SRP106608	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.23495
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15885
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
hsa-miR-1587	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
hsa-miR-3189-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14205
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35888
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87356
Perturb_12241_KO_ZMYND8_SRP343066	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.76854
Perturb_8139_KD_IGF2BP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.22513
Perturb_13372_KD_RPRD1B_SRP362755	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.2839
Perturb_8304_KD_SSB_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.68852
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16221
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RDH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35328
KDM5A	ENCODE Transcription Factor Targets	1.0	null
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20887
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46001
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64317
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95041
Perturb_14536_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.52779
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
hsa-miR-4757-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5397
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8293_KD_SUPV3L1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83305
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11528_KD_ATAC1_SRP109127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_3906_KD_SFPQ_SRP152147	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.30766
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904927
Perturb_8150_KD_SSRP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31511
Perturb_5548_KD_ASC_SRP310464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.57493
Perturb_9570_KD_CDH11_SRP318732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44012
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.880252
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867148
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33479
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12149
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_4916_KO_TFAP2A_SRP303667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02193
KYSE510	DepMap CRISPR Gene Dependency	1.0	4.06263
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19544
HCC78	DepMap CRISPR Gene Dependency	1.0	3.00137
Perturb_8237_KD_QKI_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72569
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_12256_KO_CD274_SRP215305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39867
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7069
Perturb_9939_KD_KIF1C_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.5709
Perturb_15476_OE_MYC_SRP218384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4761
Perturb_6620_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_8883_KD_CSL_SRP142324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.19148
Perturb_12641_KO_ARID2_SRP315504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.93744
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2054_KD_CHERP_SRP354316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.75998
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17756
NCIH1437	DepMap CRISPR Gene Dependency	1.0	2.74931
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17617_KO_TIP60_SRP386872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
DBNDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31585
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
Lung	GTEx Tissue Gene Expression Profiles 2023	1.0	1.04166
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51126
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87667
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94082
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5945
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40522
hsa-miR-4660	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
Perturb_9449_OE_ALS/FUS_SRP297132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Lung squamous cell carcinoma_LUSC_TCGA-21-A5DI-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10019_KD_LSM11_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.48216
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69048
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.07976
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14841_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88828
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75591
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
Perturb_8242_KD_SRSF7_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.43437
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24069
Perturb_2764_KD_FOXA1_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Peritoneal mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.02782
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9533
GSE166004_7_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7827_Mut_EIF4A3_SRP108397	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57034
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8755_KD_SON_SRP300475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8127_KD_ASCC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.32533
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84026
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
Perturb_8248_KD_LARP7_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.74622
Perturb_2458_KD_ESR1_SRP268806	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.0555
Perturb_3647_KO_KDM1A_ERP115567	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.18411
TBL1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30994
Perturb_15026_KD_KLF11_SRP267336	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30552
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPATC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45923
Perturb_3524_KD_TASOR/CNOT1_SRP337789	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_8923_KD_SMARCA4_SRP267639	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01982
Perturb_18452_KO_LTR7YB_SRP194102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.25609
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5199
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20177
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34532
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_3522_KD_CNOT1_SRP337789	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.7165
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06217
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01979
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2403
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31071
Perturb_12361_KD_SF3B5_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04573
GTEX-X4EP-0826-SM-3P5YK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60767
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26324
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56466
Perturb_8796_OE_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.33723
Perturb_344_OE|KD_SMAD1|GDF6_SRP076553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-574-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_5427_KD_ARID1A_SRP356912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.16115
Perturb_7291_KI_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.94137
Perturb_9916_KD_IGF2BP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.2916
Perturb_8097_KD_SUCLG1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.2365
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9856_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.42857
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28498
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2349_KD_PBRM1_SRP381930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.6503
GTEX-QV31-1626-SM-2S1QC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968234
Perturb_15108_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9173
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06446
Perturb_1298_KO_SOX15_SRP049465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.70465
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45729
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53515
hsa-miR-4525	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-541	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10020_KD_NUSAP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.20106
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05129
BUB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17152
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
HTRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49281
Perturb_13755_KD_KLF3/KLF4_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.43839
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876308
Perturb_8156_KD_FTO_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25194
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4141
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17451
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.90135
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
EID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90637
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0142
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64123
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26784
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16894
Perturb_3009_KD_HNF1alpha/HNF1beta_SRP067843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.88676
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0089
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_13948_KD_CDK4/CDK6_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.16325
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923703
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0626-SM-4AD6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.124
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MKN-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09695
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44717
Perturb_10032_KD_NOL12_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66053
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07751
Perturb_8057_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
ASB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43285
Perturb_12904_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
Perturb_1038_OE_C15orf48_SRP289006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.34944
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65168
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930508
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82899
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46795
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-PLZ6-0326-SM-3P61J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16507
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27457
Perturb_2715_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.5417
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81106
Perturb_9098_KD_SS18_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_14050_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.64334
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67951
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97679
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6529
Perturb_38_KD_ATRX_SRP308220	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.72985
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47285
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03
Perturb_12730_KD_INCA1_SRP221667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.03751
Perturb_12518_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4027
Perturb_9941_KD_MBNL1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.5889
Perturb_9170_KD_CFTR_ERP118933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.20375
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8164
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1265
Perturb_3735_KD_TMED3_SRP180007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.18154
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78758
Perturb_1159_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0441
SW626	DepMap CRISPR Gene Dependency	1.0	2.71733
Perturb_7760_KD_RRP6/DIS3_SRP337423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.69105
AGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6201
Perturb_4352_KD_EP300_SRP068733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.2708
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11940_KD_SMARCD1_ERP132006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.0794
GTEX-WEY5-0826-SM-4LMIH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88575
Perturb_9846_KO_DCAF15_SRP214323	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.64416
Perturb_9633_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.00423
Perturb_14321_KD_CD95L_SRP111532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.43157
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33503
Membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
brain_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.07549
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8276_KD_UPF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.99495
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96323
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30418
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56114
Perturb_519_KO_PAF1_ERP136917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.11534
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2761_KD_FOXA1_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.0185
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00176
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40178
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24069
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02191
GTEX-WOFM-0726-SM-3MJF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85889
Perturb_11575_OE_YAP_SRP273175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88496
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26338
oc314	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
Perturb_17210_KD_JUN_SRP188712	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_8269_KD_METAP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.65093
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
Perturb_13965_KD_RB1/TP53/NRP2_SRP373793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.60025
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857671
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38618
Perturb_14052_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.40843
Perturb_764_KD_SRRM2_SRP366559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.81838
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992695
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45265
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878017
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91045
Perturb_7747_KD_CNOT1_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.02744
FEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01394
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29339
GTEX-OXRL-0426-SM-3NM97	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0526
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-767-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
hsa-miR-1301	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971029
Perturb_5660_KO_ID2_SRP336141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.63212
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46489
Perturb_8108_KD_HNRNPM_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41703
CAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4522
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_3914_KD_CTNNB1_DRP003300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.3864
Perturb_7638_OE_MKL1_SRP136355	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28783
RARRES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6636
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45265
GTEX-XPVG-0926-SM-4B651	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49779
GSE107594_0_v_1_hmga2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6617_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_2069_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38989
GNA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69803
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3939_KD_APC_SRP199093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.34162
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4589
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85523
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.33404
Perturb_8455_KO_PLAC8_SRP370882	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.03718
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49432
GTEX-XLM4-0426-SM-4AT54	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12538
Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4743	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
LN319	DepMap CRISPR Gene Dependency	1.0	3.07787
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_11345_KD_ZRANB1_SRP119864	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.59442
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85345
Perturb_8287_KD_DDX55_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.26845
Perturb_9628_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.34796
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78409
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16511
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7376_KD_RBM39_ERP105778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.08621
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35126
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.970328
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2166
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28008
Perturb_11968_KO_SUZ12_SRP327198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.96718
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.09584
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11387_OE_OC2_SRP122890	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.29454
Perturb_11524_KD_NRF2_SRP092641	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2854
Perturb_13934_KD_GDE2_SRP065260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.56458
Perturb_5653_KD_EWSR1_SRP117628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40461
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05261
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2303_KD_BRCA2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.65966
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95839
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86595
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943823
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_5430_OE_ATF3_SRP308440	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.25321
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39842
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34449
Perturb_9732_KD_SLC30A8_SRP220408	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.3281
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85169
hsa-miR-378i	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Perturb_4900_KD_NANOG_SRP158631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25865
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25098
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45422
Perturb_15477_OE_MYC_SRP218384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.19747
Perturb_12666_OE_GFP_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89248
Perturb_12379_KO_SMARCA4_SRP324802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.07435
CEBPB	ENCODE Transcription Factor Targets	1.0	null
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74812
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.61871
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
SREK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23408
Perturb_8965_KO_RB1/RBL2_SRP189155	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.38686
HOXB7_01_170	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.36438
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8753_KD_ANLN_SRP083014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.9845
Perturb_9865_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33581
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14624_KD_GOT1_SRP282058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.63744
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2780_KD_HECTD1_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30991
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
Perturb_6709_OE_HNRNPK_SRP309086	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_7462_KD_CHERP_SRP126064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09071
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8384_KO_LSD1_DRP006351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.10964
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
Perturb_522_KD_MAVS/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.88012
Perturb_7879_KD_EXOSC3_SRP266190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.46985
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938408
Perturb_10698_KD_CD274_SRP307356	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.49013
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2761
Perturb_8080_KD_DDX24_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.58175
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30403
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39023
C3A	CCLE Cell Line Gene CNV Profiles	1.0	2.41879
Perturb_12140_KD_PRPF8_SRP093921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97759
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78945
Perturb_8964_KO_RB1_SRP189155	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60076
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24381
Perturb_15096_KD_RELA_SRP372154	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.8556
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.6915
Perturb_8073_KD_SNORD126_SRP337208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02336
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39161
Perturb_12343_KO_PARP1/SUZ1_SRP239117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.65815
Perturb_8099_KD_UBE2L3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.85912
Derlin-1 retrotranslocation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6028
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92985
Perturb_2068_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.08159
Perturb_3904_KD_HNF4A_SRP123224	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.57062
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03599
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2723_KD_HOTAIR_SRP172688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.4407
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881778
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2805
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41353
Perturb_15556_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.4422
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.845
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8130_KD_DDX6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3278
Perturb_10225_KD_TopBP1_SRP167322	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.00135
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837868
Perturb_15384_KD_FGF13_SRP319157	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.17064
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880146
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93606
Perturb_9985_KD_U2AF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.57424
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988588
Perturb_523_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.88284
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
Perturb_12295_OE_PHGDH_SRP363494	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.78003
Perturb_9930_KD_TIA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.0974
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24862
KPNSI9S	CCLE Cell Line Gene CNV Profiles	-1.0	-3.01052
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01051
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02145
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09836
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_12370_OE_SNRPA1_SRP291347	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.97641
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60171
Perturb_5634_KD_FLI1_SRP142503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72852
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3491
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21157
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_8670_KO_SETD2_SRP291759	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.75112
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86192
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17063
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00552
RYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46274
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_2990_KO_UTX_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.99605
Perturb_11533_KD_ATAC1_SRP109127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_7648_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.3569
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60012
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87933
Perturb_13783_KD_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.58681
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45431
Perturb_6767_Mut_KDM6A_SRP343264	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.70397
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6599
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_2716_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4554
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.13098
hsa-miR-4258	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Perturb_6831_KO_MTA1_SRP173633	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.40657
Perturb_9395_OE_SOX9_SRP201900	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.5248
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24651
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
MGC-803 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_3591_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33784
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14199_KD_GATA6_ERP108557	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.97481
Perturb_9675_Mut_C9orf72_SRP242090	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.74207
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.81577
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06054
Perturb_12575_KO_NOTCH2_SRP143456	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26333
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914803
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20985
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_8145_KD_AKAP8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.02
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47666
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00917
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.45181
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34738
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16973_KD_CDK4/FYN_SRP190631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7074
Perturb_14575_KD_H2AZ1_SRP314800	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_2882_KD_MAGOHB_SRP144009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.0308
Perturb_2076_OE_PUM1_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.4242
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19255
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.50417
Perturb_1039_OE_MOCCI_SRP289006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.94367
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4675
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904689
EZH2	ENCODE Transcription Factor Targets	1.0	null
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16509
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05876
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
hsa-miR-4267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.64
Perturb_15998_KD_LUCAT1_SRP221619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.93818
CBX3	ENCODE Transcription Factor Targets	1.0	null
Perturb_15211_OE_MIR130B_SRP373399	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91755
Perturb_15587_KD_EP300_SRP355992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.2727
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5547_KD_ASC_SRP310464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84273
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902977
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03622
Perturb_10351_KO_NSD2_SRP229726	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14315_KO_PDE10A_SRP300922	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.23406
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00761
Perturb_8971_KD_COX4I1_SRP305486	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44361
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11544_KD_NPM1_SRP175176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917494
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15783
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4015
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17078
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_3885_KD_EIF2B5_SRP124930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.95467
Perturb_8838_OE_MLLAF4_SRP293797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.07508
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7177_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.23456
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54015
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10417
Perturb_9938_KD_DKC1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.21759
Perturb_474_KO_HDLBP_SRP261899	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.669
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7987
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893381
efo21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perturb_14114_KD_ATF7IP_SRP156289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.15355
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50218
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834764
Perturb_10023_KD_RCC2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.22916
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.773018
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54399
Junctional sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_9676_KO_C9orf72_SRP242090	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.99297
GSE140445,GSE140448_1_v_0_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1105
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45532
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38713
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825099
Perturb_13704_KD_SMARCA2_SRP247495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.83285
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1113
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0633
hsa-miR-4515	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
Perturb_7490_KD_SIN3B_SRP173465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.88201
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32987
Perturb_3753_KD_MIB1_SRP408817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57579
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992695
Perturb_3997_KO_HIC2_SRP317427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.34772
PMC9894241-pnas.2211429119.sd05.xlsx-G8_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_406_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.31464
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.8692
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10431_KD_circFAT1_SRP261305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825099
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55974
Perturb_9407_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.80035
Acute closed-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29145
hsa-miR-553	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Perturb_2781_KD_HECTD1_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_2321_KD_RBM15_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37678
Perturb_3903_KD_HNF4A_SRP123224	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.44324
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.57066
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4498
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859853
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49962
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14255
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04551
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.8273
MEC1	CCLE Cell Line Gene CNV Profiles	1.0	1.74249
smoothmuscle_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12264
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9983_KD_TAF15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.51948
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9858_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.05068
Perturb_13601_KD_YAP1_SRP337871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.303
Perturb_2525_KD_SYF2_SRP185438	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61919
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13701
Perturb_1097_KO_CIC_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.67566
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24997
Perturb_450_OE_SIX4_SRP166969	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.0107
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1805
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
Perturb_8383_KO_LSD1_DRP006351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81026
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
GTEX-U3ZN-0526-SM-4DXTH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03524
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-889	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22173
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.69583
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS513	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71415
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE211128_7_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7824_KD_EWSR1_SRP106906	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.26927
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.124
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992695
Perturb_8342_KD_NREP_SRP233376	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.3616
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832909
Perturb_15142_KD_LINC00473_SRP257261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.14139
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98943
Perturb_498_KD_MAVS/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.9494
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26884
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61281
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05084
Perturb_8920_KD_P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.62758
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54481
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87141
GTEX-TMMY-1026-SM-4DXTI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31223
Perturb_4237_OE_ERG/FLI1_SRP403488	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.71693
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8951
Perturb_6882_KD_NAA40_SRP308012	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.68532
Perturb_10061_KD_CCAR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.83146
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975307
Perturb_7821_Mut_BAZ1A_SRP100570	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14578_KD_GPX1_SRP119929	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.3311
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_17639_OE_WWTR1_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hsa-miR-378e	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-371-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7865
Perturb_8891_OE_ANT2_SRP381834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60062
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68432
hsa-miR-3923	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825099
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0224
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26927
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53627
Perturb_9185_OE_ZNF593AS_SRP298754	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.44424
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9697_KO_CHD8_SRP061880	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35334
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7336_KD_SUGP1_SRP286876	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.6147
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11447
postcentral gyrus, left, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839299
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_5657_KD_EF1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_15490_KO_BCOR_SRP168753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.81146
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22197
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_394_KO_FOXM1_SRP272209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.62092
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77188
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72378
Perturb_10131_KD_GATA1_SRP090317	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.07382
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
Perturb_9929_KD_TARDBP_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.68233
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
Perturb_6834_OE_GAS5_SRP191965	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.40614
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
MAP4K5_knockdown_199_GSE61497	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.69432
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40631
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	1.67677
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99191
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916443
chr1_21822324_G_A_b38	GTEx eQTL 2025	1.0	1.11096
GSE212074_0_v_1_pus1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
Perturb_9886_KD_ABCF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.30471
ZNF345	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91327
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.50017
Perturb_8359_KD_HNF4a_SRP365071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.16822
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7136_KD_SETD8_DRP009168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.1975
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65078
Perturb_15506_KD_MED1_SRP179971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0494
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96175
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87806
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827921
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
GSE215086_0_v_2_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.871926
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
Perturb_13756_KD_KLF4_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90114
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6142
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30654
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95936
Perturb_15347_KD_SMARCD1_SRP269169	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.27155
Perturb_538_OE_EWS_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.82653
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7307_KD_IER3_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5861
Perturb_15558_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.30097
Perturb_7513_Mut_TFIIS_SRP200805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34426
Perturb_2329_KD_SF3B5_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.95052
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11349_KD_NFAT1_SRP173011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7156_KD_ARID1B_SRP366384	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.15156
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00702
Perturb_8113_KD_U2AF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_6786_Mut_KRAS_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.5216
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931494
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8928_KD_CHD4_SRP350011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95339
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3976
Perturb_8030_KD_PURPL_SRP383476	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.79438
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9311_KD_Trp53_SRP320074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83106
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07426
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876337
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1265
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.64697
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47213
VIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20435
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835483
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_3589_KO_DDX6_ERP024006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.83239
Perturb_6784_KD_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.46151
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9535
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18842
GTEX-XPT6-2226-SM-4B66R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99653
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50811
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05735
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_12953_KO_ZFP36L2_SRP251843	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53008
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.41461
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14804
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27086
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7646_KD_METTL3_SRP154311	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2209
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7PM-0426-SM-3NM91	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39547
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13698
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14328_KD_GRHL2_SRP157074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833522
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70535
Perturb_14653_KD_IQANK1_SRP102315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.92444
TC32	DepMap CRISPR Gene Dependency	1.0	3.8182
Perturb_10108_KD_EIF4A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.86117
Perturb_741_KD_KDM4A_SRP181840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4128
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_7812_KD_RRP40_SRP091999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25704
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34082
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05321
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
hsa-miR-4292	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
SLC2A4RG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81257
RUNX2	ChEA Transcription Factor Targets	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45264
Perturb_16366_OE_DUX4_SRP225205	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.51902
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0505
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92812
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915791
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11026
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2286
Perturb_9684_KD_POU3F2_SRP242009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.97304
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.52025
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_5656_KD_CT_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.46756
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05261
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19625
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
Perturb_11531_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.2757
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3953
Perturb_12729_KD_INCA1_SRP221667	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26952
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_14051_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.94604
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3930_KO_FURIN_SRP197346	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8966
Perturb_17241_KD_IRF1_SRP337933	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.92611
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30864
Perturb_6707_KD_ELOA_SRP314942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47077
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901735
GTEX-RTLS-0426-SM-2TF5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61501
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20598
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18174
Perturb_12236_KO_HIF1A/HIF2A_SRP130942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.07561
Perturb_15452_KD_circCSNK1G3_SRP139940	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.61825
Perturb_2877_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.15739
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63327
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84381
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2564_KD_GATA3_SRP188712	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.95709
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917331
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35388
Perturb_316_OE_EHF_SRP309336	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.71516
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8322_KD_ARID2_SRP059066	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52109
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0031
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3632_KO_HDAC8_SRP355605	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_15141_OE_LINC00473_SRP257261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48434
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3373
Perturb_11933_KD_RNF5_SRP276909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.06379
Perturb_8161_KD_SF3B1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.5686
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66591
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Gene_Name_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.50007
Perturb_8284_KD_CSTF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28624
PCNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74889
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7890_KD_DHX15_SRP313394	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.16378
Perturb_8110_KD_NAA15_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59294
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48463
Perturb_15510_KD_APC_SRP345432	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.09252
Perturb_4246_KD_GATA3_SRP372594	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.92262
BGC-823 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41223
GTEX-S341-1026-SM-4AD71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15958
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72242
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76506
Perturb_9861_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.74543
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4299	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
Perturb_452_OE_MYC_SRP171977	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
AGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16873
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893154
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4634
Perturb_2373_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57298
Lung squamous cell carcinoma_LUSC_TCGA-77-8138-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25068
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836843
Perturb_12315_KO_AGO1_SRP136692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_3748_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.81738
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
GTEX-X5EB-2626-SM-4E3HZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14302
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19625
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9984_KD_TBRG4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.2237
JHOC5	CCLE Cell Line Gene CNV Profiles	1.0	1.35975
Perturb_8241_KD_SRSF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.13296
Perturb_9009_KD_RELA_SRP061289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.57975
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.28274
Perturb_15801_KD_INTS13_SRP271267	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55297
Perturb_7234_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86973
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188570,GSE188571_3_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.58167
Perturb_3948_KD_ETV5_SRP137003	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.45355
F8A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21086
Perturb_9927_KD_SRSF5_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.0507
ES5	DepMap CRISPR Gene Dependency	1.0	2.98903
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52982
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13972
colon_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.34407
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31535
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.94439
GSE176008_7_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4717-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Perturb_18453_KO_LTR7YB_SRP194102	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.27404
RNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90538
Perturb_505_KD_WTAP_SRP039397	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.30336
RNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44182
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	2.73332
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984033
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2717
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_8122_KD_SNRNP200_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.71686
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.259
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56989
Perturb_14535_KO_NTNG1_SRP278999	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.203
NUGC3	CCLE Cell Line Gene CNV Profiles	1.0	1.93697
Perturb_8332_KD_SETD2_SRP167173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.29257
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96753
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_6684_KD_SMARCA2_SRP378606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
WM115	DepMap CRISPR Gene Dependency	1.0	4.73697
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_13514_KD_MYCNOS1_SRP292532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.55908
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
MSRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16029
GTEX-UPJH-0726-SM-4IHJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99908
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	1.11399
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10281
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_9837_KD_GCN2_SRP248465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.54957
Perturb_9860_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.5674
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
Perturb_15455_KD_E2F1_SRP165775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.66259
ELF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_4340_OE_MIR9/MIR124_SRP271657	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.865336
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00502
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8922_KD_ARID1A_SRP192521	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9966
Perturb_14630_KD_MSI1_SRP067129	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.74331
Perturb_6442_KO_RHO_SRP134183	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.61544
Perturb_13662_KD_E2F1_SRP225180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.05202
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26112
NCIH1092	CCLE Cell Line Gene CNV Profiles	1.0	1.39129
Perturb_3602_KO_ACTB_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.09841
Perturb_409_KO_IRE1_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.80141
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886452
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44003
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.18149
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-S7SF-2226-SM-3K2BG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27969
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
Perturb_15023_KD_RelA_SRP078053	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.63379
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8798_OE_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4813
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	8.57861
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.93033
C10	DepMap CRISPR Gene Dependency	1.0	2.99394
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8605
Perturb_3905_KD_SFPQ_SRP152147	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.07549
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.58572
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09836
GTEX-XPT6-0426-SM-4B672	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23839
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.21215
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4427
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-3161	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2118
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16309
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22938
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8488_KO_GOLPH3_SRP401813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13217
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54188
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12051
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34151
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3604
Perturb_11732_KO_KDM5A_SRP292672	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.45791
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7911
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97105
Perturb_7379_KD_SMG5_ERP122822	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.82435
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848709
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	1.0	3.00883
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60924
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35916
95T1000	DepMap CRISPR Gene Dependency	1.0	2.74408
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861467
TTC38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48593
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77594
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31948
RCOR1	ENCODE Transcription Factor Targets	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95692
Perturb_2074_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.81603
Perturb_9631_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.93118
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15447_KD_HDAC5_SRP273298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.83182
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S32W-2426-SM-2XCAT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0988
Perturb_10009_KD_PKM_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31946
Perturb_9934_KD_AKAP8L_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.1182
smooth muscle	HPA Tissue Gene Expression Profiles	1.0	1.23374
Acute Myeloid Leukemia_LAML_TCGA-AB-2859-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_8227_KD_HDGF_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.44225
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05956
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15488
Perturb_272_KO_ADIRFAS786_SRP366780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.87933
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89382
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45053
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14548
SKNDZ	DepMap CRISPR Gene Dependency	1.0	2.00489
Perturb_3911_KD_SOX9_SRP118481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.31905
Perturb_7864_KD_YTHDC1_SRP226173	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49747
ERH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11025
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19367
Perturb_2103_KD_CDC73_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53662
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8814_KD_YAP1/WWTR1_SRP284279	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.87578
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46653
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1345_KD_ARID1A_SRP336358	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_12029_OE_ID4_SRP333901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9329
Perturb_6887_KO_PFDN5_SRP273783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.61955
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07254
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.70082
Perturb_2758_KD_PRMT1_SRP214436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.92558
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81222
TMEM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.42162
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00958
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982832
Perturb_8107_KD_FIP1L1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6639
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5902
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27162
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36047
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.769743
Perturb_10075_KD_AQR_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.40418
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.87862
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49383
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68124
Perturb_14894_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.37378
Perturb_8800_KD_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.56201
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.966
Perturb_7431_KO|KD_RBFOX2|RBFOX1_SRP068106	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.56321
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923703
Perturb_8260_KD_RPLP0_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.27351
Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RH4	DepMap CRISPR Gene Dependency	1.0	2.22917
Perturb_10106_KD_DDX6_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.42291
Perturb_4759_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.3231
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7179_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.48645
SPRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54638
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0238
Perturb_5297_KD_INSR_SRP045438	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.51944
BTBD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73142
hsa-miR-515-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.891406
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.25068
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69648
Perturb_14874_KO_H12_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.58568
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_10674_KD_PLAG1_SRP332281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.92806
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
Perturb_14881_KO_H15_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.31953
Perturb_15812_Mut_RP2_SRP255721	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.74397
Perturb_17642_OE_YAP_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.45278
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2728_KD_NEK2_SRP231163	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85428
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PRDM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6565
Perturb_8872_KD_JCAD_SRP115209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.3786
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19267
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_9933_KD_AKAP8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6586
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.988588
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993226
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967903
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
5637 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
Perturb_2476_KD_PHF8_SRP229951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.77966
Perturb_9973_KD_CSTF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.2514
CTCF	ENCODE Transcription Factor Targets	1.0	null
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08967
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18571
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40433
Perturb_9173_KD_METTL3_SRP238262	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55323
C1orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41114
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9063_KD_NANOG_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.79475
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
Perturb_1058_KO_ALPG_SRP277076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31095
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02074
ESRRB	ChEA Transcription Factor Targets	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24826
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11824
Perturb_7628_KD_HNRNPL/UPF1_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.69688
Perturb_10246_OE_RUNX1_SRP228597	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_599_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.19005
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9127
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9288_OE_KRAS_SRP172671	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.39455
Perturb_13017_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.77871
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12747
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.32669
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92455
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
Perturb_7757_KD_MPP6_SRP337423	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.09872
Perturb_2383_OE_ROR2_SRP293436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.72891
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86715
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22261
hsa-miR-195	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
Perturb_10072_KD_RBFOX2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47143
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10654
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2335_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.0444
Perturb_12933_KD_CDK9_SRP340404	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7075
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3817
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824098
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53731
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82568
Perturb_2066_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.7419
Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.031759
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80765
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19073
GTEX-P44H-1026-SM-3NM96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14873
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9852
SETDB1	ENCODE Transcription Factor Targets	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4011
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00755
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.737187
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.97539
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8086_KD_EIF4G1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.08894
Perturb_2067_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38702
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16533
Perturb_8195_KD_SMN1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1813
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.39247
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25446
GSE210373_0_v_1_cntnap4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7231_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.29151
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_3262_KO_VHL_SRP337931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_6685_KD_SMARCA2_SRP378606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.46157
Perturb_8060_KO_TP53_SRP182675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.7366
Perturb_9972_KD_BCLAF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.98067
Perturb_2073_KD_BMAL1_SRP041298	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1663
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866617
Perturb_13390_OE_NSD2_SRP199225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.23368
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21099
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29491
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857671
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81289
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06578
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59184
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25378
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
Perturb_7956_KD_EXOSC3_SRP222099	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.47946
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
BSG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45139
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24826
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27975
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67092
Perturb_8088_KD_FMR1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.9656
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67775
Perturb_443_KD_SBF2AS1_SRP116042	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.5135
hsa-miR-15b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866685
Perturb_8492_KD_Mir34a_SRP133851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.9373
GTEX-R55E-1126-SM-48FDZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03057
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8799_OE_HOTAIR_SRP352837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48446
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37026
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29673
Perturb_7752_KD_YTHDF2_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.4976
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-4493	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
AP5B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41416
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88106
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
Perturb_14553_KO_HNRNPF_SRP296872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.23393
Perturb_7316_KO|KD_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.18228
Perturb_501_KD_TLR3/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06107
BBS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84468
mRNA_TCEA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_8347_KD_YY1_SRP286033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7232
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32621
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_12350_KD_CDC73_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.78641
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33681
hsa-miR-218	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26137
Perturb_8354_KD_PtenTraf3_SRP337419	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.15349
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09632
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0995
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC2	ChEA Transcription Factor Targets	1.0	null
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20988
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_457_KO_USP22_SRP199797	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3229
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13291
Perturb_17538_KO_MAPK7_SRP265870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.84178
Perturb_9862_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.29701
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92089
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914803
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-378d	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
Perturb_2374_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1408
Perturb_10199_KD_RUNX1/RUNX1T1_SRP291095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.39525
Perturb_93_KD_ANXA4_SRP127547	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.80665
Perturb_6619_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.1804
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03136
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
RBMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45078
STK11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
Perturb_3254_KD_TSR2_SRP092068	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.03896
Perturb_9841_KD_KDM6A_SRP254623	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.79451
Perturb_14609_KD_SIK3_SRP118895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.77831
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923703
Perturb_2385_KO_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919878
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34465
Perturb_701_KO_TET2_SRP200817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.33367
Perturb_3610_KO_BCL7B_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.6442
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09899
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74198
HT1197	CCLE Cell Line Gene CNV Profiles	1.0	1.36226
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2296_OE_PTEN_SRP175252	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26692
Perturb_8471_Mut_IDH1_SRP099826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7662
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35542
hsa-miR-4758-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Perturb_3889_KD_HNRNPC_SRP115023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.81927
Perturb_7801_KD_PAF1_SRP064356	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.99716
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36087
Perturb_7378_KO_PHF3_ERP112687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.833
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11939_KD_SPI1_ERP119419	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.65268
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976659
Perturb_8929_KD_CHD4/ARID1A_SRP350011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.16042
GTEX-OHPK-0426-SM-3MJH3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27423
Perturb_10022_KD_PSIP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.64423
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34021
Perturb_11543_KD_DHX9_SRP175176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.8026
Perturb_8822_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.10038
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857744
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.879
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	1.52174
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825099
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46097
Perturb_3253_KD_RPS19_SRP092068	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.41583
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	4.66304
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8993_OE_LIMA1_ERP128082	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.9146
Perturb_7708_KD_Spt6_SRP132004	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.52128
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32683
Perturb_9915_KD_IGF2BP2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7981
Perturb_11566_Mut_FOXM1_SRP371023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.45191
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
hsa-miR-1250	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
blood vessel	GTEx Tissue Gene Expression Profiles	1.0	1.45925
Perturb_8486_OE_PLXNB2_SRP282509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.7484
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90627
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967826
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51801
DU4475	DepMap CRISPR Gene Dependency	1.0	3.5637
Perturb_12931_KO_KAT7_SRP212620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.16444
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07134
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98274
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_1358_KD_GANAB_SRP299805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.14086
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21854
BL70	DepMap CRISPR Gene Dependency	1.0	3.37174
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65862
Perturb_7867_KD_RNaseH2A_SRP252761	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.5238
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49488
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69045
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kmp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29496
membrane part	GO Cellular Component Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_10182_KD_RAD21_SRP225887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.68928
Perturb_2372_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.8288
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03832
Perturb_14056_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.29181
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46489
Perturb_5563_KO_KDM4C_SRP375293	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14663
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19775
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5047
Perturb_15348_KD_SMARCD3_SRP329316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.44946
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910562
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1265
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12756
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-UJHI-0326-SM-4IHJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05059
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49156
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85656
Perturb_15185_KD_CPSF1_SRP186931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.55696
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9836_KD_GCN2_SRP248465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.61543
Perturb_231_KD_HIF1A_SRP100624	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.39856
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.92
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.02466
Perturb_8018_KO_PXR_SRP257678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33086
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17471
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8647
Perturb_9864_KO_MYB_SRP192629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.56851
Perturb_10024_KD_SRFBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.8041
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_500_KD_RL6/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19134
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875277
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43524
Perturb_3621_KO_SMARCC1_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.95522
Perturb_3841_KD_NFE2L2_ERP105460	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.44993
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42455
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26641
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39722
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-16	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04555
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
Perturb_7732_KD_RRP6_SRP062389	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.1095
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96174
hsa-miR-654-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30808
Perturb_444_KD_AKR1B1_SRP121474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AGFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27698
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37594
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-15a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Perturb_7767_KD_IER3AS1_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0176
Perturb_13043_KD_TARDBP_SRP069787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01596
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.61428
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57261
Perturb_2845_KD_FOXA1_SRP288463	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.71626
LINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2986
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13041_KD_FUS/TAF15_SRP069787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.44747
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7203_KD_DHX9_SRP080966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2389
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.735
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48834
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77523
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2075_KD_PUM1_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.7208
Perturb_14127_KO_TP53/CDKN2A/PTEN/NF1_SRP258861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.3639
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7948
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28677
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE212330_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13907_KD_UBE3A_SRP124518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.18966
Perturb_546_KD_EF1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_12517_KD_TRA2B_SRP221583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6232
Perturb_8839_KD_WDR5_SRP258987	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2273
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2338_KD_MUC1C_SRP300048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87348
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51999
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25356
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65319
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926531
Perturb_8203_KD_HLTF_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.76921
Perturb_2388_KO_CARM1_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.63836
SLC7A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02931
Perturb_15512_KD_FOXA1_SRP353748	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ZNF217_ER-Nearest_Ensembl_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52436
Perturb_10015_KD_HNRNPC_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.4829
Perturb_4392_KD_RNF5_SRP276909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.58323
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869488
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8886_OE_FOXM1_ERP109084	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_6436_OE_HOXA10AS_ERP131886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.04803
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_2078_OE_PUM2_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.1448
Perturb_15456_KO_GPRC5A_SRP165862	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26518
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20806
Perturb_17233_KD_KLF2_SRP389914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.68186
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31332
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8194_KD_SAFB2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.63978
Perturb_12372_KD_SKP2_SRP297799	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04525
Perturb_9112_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.48443
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12982
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
HCT-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117