association	dataset	threshold value	standardized value
CALML5	Pathway Commons Protein-Protein Interactions	1.0	null
LIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7801
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DLAT	Pathway Commons Protein-Protein Interactions	1.0	null
SIMA	DepMap CRISPR Gene Dependency	1.0	2.63001
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64142
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.394
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.174274
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913537
BL6024 (WDR4)	NURSA Protein Complexes	1.0	null
Transcription factor TFIIF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.57
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3125
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36796
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106692
TECR	Pathway Commons Protein-Protein Interactions	1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06148
esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.6557
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
Galectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.296
CLIC1	Pathway Commons Protein-Protein Interactions	1.0	null
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995057
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827877
RCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60592
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866975
chr19_38769904_T_A_b38	GTEx eQTL 2025	1.0	3.61214
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12688
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.29673
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34398
Uterine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54407
GTPBP4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851662
PGK1	Pathway Commons Protein-Protein Interactions	1.0	null
SM-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46388
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23909
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46167
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64461
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03353
CACNA1G	Pathway Commons Protein-Protein Interactions	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.145204
LN319	DepMap CRISPR Gene Dependency	1.0	3.3443
Cervical epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051721
PDHA2	Pathway Commons Protein-Protein Interactions	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958036
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04189
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.941687
head and neck squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074469
Oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
CSF1	Pathway Commons Protein-Protein Interactions	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6757
verruciform xanthoma of skin	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09293
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.5833
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381535
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51266
Tongue carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
KBTBD6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
Nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.537
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3791
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO21	DepMap CRISPR Gene Dependency	1.0	2.3683
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
Nem1-Spo7 phosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
STAT3	ENCODE Transcription Factor Targets	1.0	null
CDK5RAP2	Pathway Commons Protein-Protein Interactions	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8333
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	283.968
MOLM13	DepMap CRISPR Gene Dependency	1.0	3.13872
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBFA	Pathway Commons Protein-Protein Interactions	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41097
BL2152 (NEK7)	NURSA Protein Complexes	1.0	null
SMC6	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05471
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46811
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58331
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.022
CLIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96647
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
ZNF586	Pathway Commons Protein-Protein Interactions	1.0	null
SKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56816
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950766
RPL10A	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPTN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3188
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83768
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3086
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998765
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6424
TRABD2A	Pathway Commons Protein-Protein Interactions	1.0	null
BF-10-IO69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.734638
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.5585
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4532-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP134	DepMap CRISPR Gene Dependency	1.0	2.80943
Gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
ANKS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32524
RPL17	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32314
PHF6	Pathway Commons Protein-Protein Interactions	1.0	null
SNU840	DepMap CRISPR Gene Dependency	1.0	3.13453
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04326
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.381154
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5501
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869652
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34477
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25431
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09036
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
DUT	Pathway Commons Protein-Protein Interactions	1.0	null
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06142
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976393
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
BL439 (NCOA3)	NURSA Protein Complexes	1.0	null
MAP3K5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AD-18-XC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.889639
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.351002
TENC1	Pathway Commons Protein-Protein Interactions	1.0	null
Keratocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302118
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907918
stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.41848
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
FD-62-ZB67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.00759
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6754
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20923
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70756
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47617
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931397
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
BL1012 (ZHX1)	NURSA Protein Complexes	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.701489
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942721
SB-94-ZA83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.38163
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119945
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31537
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447961
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3781
NUP88	Pathway Commons Protein-Protein Interactions	1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28747
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94116
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39451
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.76399
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1179
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17184
Malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
CBR3	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1746
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09943
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84149
supramarginal gyrus, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968274
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
TRIM21	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
DC-47-KV62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256708
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25731
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLE	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
HSPA6	Pathway Commons Protein-Protein Interactions	1.0	null
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36653
ovary adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382594
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Perturb_3243_KD_UCA1_SRP124072	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CYP4Z2P	Pathway Commons Protein-Protein Interactions	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072797
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
ovary cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065894
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048873
WIPI1	Pathway Commons Protein-Protein Interactions	1.0	null
GABRR1	Pathway Commons Protein-Protein Interactions	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
EXOSC9	Pathway Commons Protein-Protein Interactions	1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20091
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
hsa-miR-3972	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34314
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35086
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.867434
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00535
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91307
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21159
Trypomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
B16-F1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
DAZAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862666
MYO18A	Pathway Commons Protein-Protein Interactions	1.0	null
SNRNP70	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069912
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32451
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043093
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87654
FAM117B	Pathway Commons Protein-Protein Interactions	1.0	null
JUP	Pathway Commons Protein-Protein Interactions	1.0	null
AA-85-LB25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355849
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941943
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198064
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060113
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10672
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40993
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46743
H1FX	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT6A	Pathway Commons Protein-Protein Interactions	1.0	null
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35807
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
chr19_38792761_C_G_b38	GTEx eQTL 2025	1.0	4.2098
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61746
Infection By Cryptococcus Neoformans	DisGeNET Gene-Disease Associations	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2284
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.0828
Umbilical vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
TMED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53048
adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.213959
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963048
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48199
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21545
18667080-TableS4	GeneSigDB Published Gene Signatures	1.0	null
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221172
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.293
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946225
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
Amniocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912533
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8967
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.98977
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75812
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
EMD	Pathway Commons Protein-Protein Interactions	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06439
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22082
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33124
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46985
Neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35736
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9826
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51151
MAP3K1	Pathway Commons Protein-Protein Interactions	1.0	null
Galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
RPL10	Pathway Commons Protein-Protein Interactions	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310164
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45429
LSM2	Pathway Commons Protein-Protein Interactions	1.0	null
Decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
Villous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
women	GeneRIF Biological Term Annotations	1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
MCM5	Pathway Commons Protein-Protein Interactions	1.0	null
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
Fetal adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
BRIX1	Pathway Commons Protein-Protein Interactions	1.0	null
F7	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51053
HIST1H2BL	Pathway Commons Protein-Protein Interactions	1.0	null
MCF2L2	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amyloid tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
PITX2	Pathway Commons Protein-Protein Interactions	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5081
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
Amnion epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26793
EIF5A2	Pathway Commons Protein-Protein Interactions	1.0	null
HOXB5	Pathway Commons Protein-Protein Interactions	1.0	null
epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5838
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832581
HCC95	DepMap CRISPR Gene Dependency	1.0	3.64797
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
TARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15859
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.585105
HCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63789
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0159
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.606514
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.25724
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03249
CAMSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56602
RI1	DepMap CRISPR Gene Dependency	1.0	2.59887
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.766
XKRX	Pathway Commons Protein-Protein Interactions	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6927
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPA2	Pathway Commons Protein-Protein Interactions	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	292.984
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3008
TMEM51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02219
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
KLF10	Pathway Commons Protein-Protein Interactions	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
CRCGN011_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06895
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27544
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08426
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13749
USP48	Pathway Commons Protein-Protein Interactions	1.0	null
Classical Galactosemia	DisGeNET Gene-Disease Associations	1.0	null
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
NPC1L1	Pathway Commons Protein-Protein Interactions	1.0	null
KRT31	Pathway Commons Protein-Protein Interactions	1.0	null
TDG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3052
RRP1B	Pathway Commons Protein-Protein Interactions	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1875
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064679
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.355
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	302.819
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82878
RPS12	Pathway Commons Protein-Protein Interactions	1.0	null
PRDX6	Pathway Commons Protein-Protein Interactions	1.0	null
Stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.115
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38647
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
GSE146687_2_v_1_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856633
RCBTB1	Pathway Commons Protein-Protein Interactions	1.0	null
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.142
CCM2L	Pathway Commons Protein-Protein Interactions	1.0	null
T24	DepMap CRISPR Gene Dependency	1.0	3.24509
Perturb_5605_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
POP4	Pathway Commons Protein-Protein Interactions	1.0	null
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068524
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0335
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29344
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4377
USP38	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96266
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216757
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65302
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.705
HaCaT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35346
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20235
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08479
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67725
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90631
skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23353
CCDC106	NURSA Protein-Protein Interactions	1.0	1.06443
laminin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079444
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.299
HOXA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59491
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981752
oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117074
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
SAGA-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
GBAS	Pathway Commons Protein-Protein Interactions	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9324
DLD-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.255
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29783
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922313
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
Interstitial lung disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77601
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59097
CRCGN015_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66744
RAD50	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Tca-8113 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Perturb_8931_KD_HNRNPL_SRP295547	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5645
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tongue-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	9.0583
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.935385
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84771
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8158
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45684
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GART	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7075
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8681
T84	DepMap CRISPR Gene Dependency	1.0	2.62287
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13749
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77059
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.949228
USP15	Pathway Commons Protein-Protein Interactions	1.0	null
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88194
Perturb_14766_KD_HDAC5_SRP265842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.9237
HSD17B10	Pathway Commons Protein-Protein Interactions	1.0	null
increased keratinocyte proliferation	MGI Mouse Phenotype Associations 2023	1.0	null
PPP2R2B	Pathway Commons Protein-Protein Interactions	1.0	null
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65768
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72924
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XE-69-AT35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241413
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.3389
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065734
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75256
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846844
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	4.77954
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.602
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068245
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58096
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
KRT81	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJC10	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07101
TBC1D2B	Pathway Commons Protein-Protein Interactions	1.0	null
PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06443
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.2287
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
POF1B	Pathway Commons Protein-Protein Interactions	1.0	null
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12053
PANC0813	DepMap CRISPR Gene Dependency	1.0	2.014
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.67978
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.047
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.52
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64117
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12217
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
TUT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
interleukin-10 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
Serine C-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899841
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.574
Hybridoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056008
CSTB	Pathway Commons Protein-Protein Interactions	1.0	null
PUM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73456
myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.460305
MYO1D	Pathway Commons Protein-Protein Interactions	1.0	null
CYBA	Pathway Commons Protein-Protein Interactions	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171789
Perturb_15368_KO_AK2_SRP326644	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3461
BE-04-AN21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.758895
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39445
Esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.396
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28147
NCI-H2227	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05224
Esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALB	Pathway Commons Protein-Protein Interactions	1.0	null
COPS5	Pathway Commons Protein-Protein Interactions	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POLR2A	Pathway Commons Protein-Protein Interactions	1.0	null
pavement epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232632
Integrin alphav-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865322
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
CHAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30515
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2077
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.168449
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7554
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21864
Cervical epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13766
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3327
DSP	Pathway Commons Protein-Protein Interactions	1.0	null
increased circulating free fatty acids level	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38375
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104123
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9539
Chorioallantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
ABRA	Pathway Commons Protein-Protein Interactions	1.0	null
SH3RF1	Pathway Commons Protein-Protein Interactions	1.0	null
delayed wound healing	MGI Mouse Phenotype Associations 2023	1.0	null
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6446
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161602
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9545
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0016
18667080-TableS9	GeneSigDB Published Gene Signatures	1.0	null
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07266
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64886
ATP5O	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262501
MSTO211H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60415
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2883
SERPINB4	Pathway Commons Protein-Protein Interactions	1.0	null
cervix uteri carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.564112
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
CRCGN017_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01095
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6725
Asthma	DisGeNET Gene-Disease Associations	1.0	null
EEF1A2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14018
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50218
DDX51	Pathway Commons Protein-Protein Interactions	1.0	null
epithelial ovarian cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374993
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4799
KRT1	Pathway Commons Protein-Protein Interactions	1.0	null
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26141
increased keratinocyte apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236522
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398672
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MCF7_KD-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM91A1	Pathway Commons Protein-Protein Interactions	1.0	null
ARG1	Pathway Commons Protein-Protein Interactions	1.0	null
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57953
Extravillous trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048465
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852257
KRT82	Pathway Commons Protein-Protein Interactions	1.0	null
CME1	DepMap CRISPR Gene Dependency	1.0	3.86731
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06045
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98354
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
KDM4A	ENCODE Transcription Factor Targets	1.0	null
TNFRSF18	Pathway Commons Protein-Protein Interactions	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
pre-B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.327
NDUFA4	Pathway Commons Protein-Protein Interactions	1.0	null
NOP56	Pathway Commons Protein-Protein Interactions	1.0	null
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843874
ags cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25858
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GLTSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HN	CCLE Cell Line Gene CNV Profiles	1.0	1.65811
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked intellectual disability-short stature-overweight syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
HSPE1	Pathway Commons Protein-Protein Interactions	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6474
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.205
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
GLUL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22583
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070912
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
RCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18387
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.333
CSTF1	Pathway Commons Protein-Protein Interactions	1.0	null
KRT2	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.45391
KRT24	Pathway Commons Protein-Protein Interactions	1.0	null
FTSJ3	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
CPEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34376
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7417
glandular stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.463787
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68224
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
MYO1B	Pathway Commons Protein-Protein Interactions	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964825
TPH1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL28	Pathway Commons Protein-Protein Interactions	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913987
Head and neck carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9767
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26807
ovarian cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.798692
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051871
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876975
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.456828
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0744
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
increased circulating free fatty acids level	MGI Mouse Phenotype Associations 2023	1.0	null
Monocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084298
Larynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04085
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2395
TFG	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41527
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89102
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	2.93014
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28692
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3533
ZNF354B	Pathway Commons Protein-Protein Interactions	1.0	null
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.965026
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04147
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92822
AC-36-TL21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.364179
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Perturb_14765_KD_HDAC5_SRP265842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
LD-69-ZV56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.417762
MAP3K3	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405555
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CALCOCO2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31901
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04189
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35967
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29896
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12016
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
KRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15389
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15447
EPPK1	Pathway Commons Protein-Protein Interactions	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35104
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALDOA	Pathway Commons Protein-Protein Interactions	1.0	null
MYL6B	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6342-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071231
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
JA-85-SW39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.769118
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39658
SNU46	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40868
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1135
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
GABARAP	Pathway Commons Protein-Protein Interactions	1.0	null
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
NUDT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80163
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20317
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251667
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991958
BL5622 (AKAP1)	NURSA Protein Complexes	1.0	null
AC-55-XA97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201616
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.114954
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
SRRT	Pathway Commons Protein-Protein Interactions	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5392
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8672
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92243
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642048
C4II	DepMap CRISPR Gene Dependency	1.0	3.57537
Squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8621
OBSCN	Pathway Commons Protein-Protein Interactions	1.0	null
STS-26T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
Breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03657
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273253
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182122
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057614
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74316
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.535
FHOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37771
cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.903275
FRMD6	Pathway Commons Protein-Protein Interactions	1.0	null
KHDRBS1	Pathway Commons Protein-Protein Interactions	1.0	null
chr19_38770330_T_C_b38	GTEx eQTL 2025	1.0	1.22312
YAE1D1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.137
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08653
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47624
small-subunit processome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.655
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22831
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
FOXP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09896
NCOR2	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
FL5.12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89897
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045412
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9836
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0081
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208342
BIN67	DepMap CRISPR Gene Dependency	1.0	2.03011
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74357
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41531
RPN2	Pathway Commons Protein-Protein Interactions	1.0	null
Epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11963
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1089
Protein N-acetylglucosaminyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05119
CCBL2	Pathway Commons Protein-Protein Interactions	1.0	null
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46206
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.477373
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
U2AF2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043023
CEP170	Pathway Commons Protein-Protein Interactions	1.0	null
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564035
laryngeal	GeneRIF Biological Term Annotations	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836625
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48948
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871496
TBL2	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22254
ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28317
Methionine adenosyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
IFT172	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78022
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3846
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199681
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.394
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44154
NAA80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66324
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.499042
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14142
KPNA1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8493
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990974
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.748
GSE210101,GSE210114_4_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A76W-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM4	Pathway Commons Protein-Protein Interactions	1.0	null
KRT3	Pathway Commons Protein-Protein Interactions	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5998
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
MAATS1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996727
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
QPCTL	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1392
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11627
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17305
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3557
CHD1	ENCODE Transcription Factor Targets	1.0	null
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
BL977 (PLK1)	NURSA Protein Complexes	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.88528
DDX54	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7413-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40182
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32698
UBTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80353
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.355004
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2848
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827372
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063446
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.8247
ANK2	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRKL	Pathway Commons Protein-Protein Interactions	1.0	null
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.19135
in situ carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.102009
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.16528
FRMPD4	Pathway Commons Protein-Protein Interactions	1.0	null
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
GSTP1	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.499042
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14912
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
NXF1	Pathway Commons Protein-Protein Interactions	1.0	null
Vestibulum vaginae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4028
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08972
TNRC6B	Pathway Commons Protein-Protein Interactions	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Atrial Septal Defect	DisGeNET Gene-Disease Associations	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
xanthomatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.573439
KYSE510	DepMap CRISPR Gene Dependency	1.0	2.73565
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1308
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66869
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884787
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
PKP1	NURSA Protein-Protein Interactions	1.0	0.216392
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4136
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15338
SKN-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
RMGI	DepMap CRISPR Gene Dependency	1.0	3.95599
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fibrinogen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
PRKCDBP	Pathway Commons Protein-Protein Interactions	1.0	null
pre-malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.412405
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16377
162 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
ZNF106	Pathway Commons Protein-Protein Interactions	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7992
BL404 (RAD9A)	NURSA Protein Complexes	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC43A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9237
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950825
Nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871496
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.799
PFN1	Pathway Commons Protein-Protein Interactions	1.0	null
DENND3	Pathway Commons Protein-Protein Interactions	1.0	null
DDX18	Pathway Commons Protein-Protein Interactions	1.0	null
FARAGE	DepMap CRISPR Gene Dependency	1.0	3.06008
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6162
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86042
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26936
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32446
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5898
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29821
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41113
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16697
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.03807
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
MYO1C	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Classic galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.956
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.7345
MAGEB10	Pathway Commons Protein-Protein Interactions	1.0	null
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71231
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37233
PREX2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994288
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
FLG2	Pathway Commons Protein-Protein Interactions	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.61
RPRD2	Pathway Commons Protein-Protein Interactions	1.0	null
BJ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
UFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66596
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1324
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5948
ONCODG1	DepMap CRISPR Gene Dependency	1.0	4.13649
AD-18-XC14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.907355
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066452
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59852
artery wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224645
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
ZNF703	Pathway Commons Protein-Protein Interactions	1.0	null
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621024
BL7472 (ADRM1)	NURSA Protein Complexes	1.0	null
PATU8988S	DepMap CRISPR Gene Dependency	1.0	2.69734
ACBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71977
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4761
OPHN1	Pathway Commons Protein-Protein Interactions	1.0	null
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9661
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7231
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integrin alpha5-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
NUAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59203
CDV3	Pathway Commons Protein-Protein Interactions	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23417
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85052
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162386
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7168
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKAP8	Pathway Commons Protein-Protein Interactions	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.946
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22304
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amnion epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202946
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6662
mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.233162
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	296.533
Ovarian cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67306
Congenital disorder of glycosylation type IIl	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
developed	GeneRIF Biological Term Annotations	1.0	null
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
KRT75	Pathway Commons Protein-Protein Interactions	1.0	null
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22774
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892597
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3443
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
CBC184 (BICD2)	NURSA Protein Complexes	1.0	null
gastric cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158555
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082789
DE-58-OW37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283335
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55629
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
C4A	Pathway Commons Protein-Protein Interactions	1.0	null
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
RAB11FIP5	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8532
Interstitial lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902135
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55941
NUP214	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP6	Pathway Commons Protein-Protein Interactions	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4224
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eyelid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208709
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1689
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090944
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29645
FABP4	Pathway Commons Protein-Protein Interactions	1.0	null
SPECC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73963
DSC2	Pathway Commons Protein-Protein Interactions	1.0	null
EPDR1	Pathway Commons Protein-Protein Interactions	1.0	null
podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.251114
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67868
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262304
GA-47-MH68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218035
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071894
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2452	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78226
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0666
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.958
GSE48812_7_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.339
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18088
pharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.594454
RPLP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831016
ovary serous adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.962053
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07376
FB-32-TL51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211626
TUBB6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vulva squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
RBM34	Pathway Commons Protein-Protein Interactions	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3781
MRPL55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47809
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.317157
RFX7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854244
Cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL36A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3443648-1752-0509-6-89-S1.xls-Sheet1-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
HMC18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94255
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067695
integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23353
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.462
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.748
AA-62-OC45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416677
Oral cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
NCIH292	DepMap CRISPR Gene Dependency	1.0	3.12781
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070078
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067012
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40117
ETV3	Pathway Commons Protein-Protein Interactions	1.0	null
LYZ	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60334
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044415
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
NCIH1299	DepMap CRISPR Gene Dependency	1.0	4.17837
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2454
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6026
PRDX2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-386-ZNF567_ZNF567	Rummagene Transcription Factor Associations 2026	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56155
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589635
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92286
HIRA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81476
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3779
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
ZZEF1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	196.397
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.0326
S100A8	NURSA Protein-Protein Interactions	1.0	0.349503
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892077
Laryngeal squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6464
84br	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
elevated	GeneRIF Biological Term Annotations	1.0	null
inner CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02928
POU2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24261
RPL27A	Pathway Commons Protein-Protein Interactions	1.0	null
RNF40	Pathway Commons Protein-Protein Interactions	1.0	null
buccal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01735
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952226
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41588
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18
PMC12222854-41598_2025_7579_MOESM6_ESM.xlsx-Breast-ALX4_ALX4	Rummagene Transcription Factor Associations 2026	1.0	null
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32003
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	2.08244
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1489
EHHADH	Pathway Commons Protein-Protein Interactions	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46733
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Esophageal squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
kato-iii cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.15948
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
GFAP	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5695
PFN2	Pathway Commons Protein-Protein Interactions	1.0	null
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.830035
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7184
middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.170054
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
exon-exon junction subcomplex mago-y14	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.506
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELMSAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02104
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88726
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21446
CRCGN016_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19526
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12959
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0297
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21889
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220187
Transcription factor TFIID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05645
RNA polymerase V complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.61633
Vulva cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
CLTCL1	Pathway Commons Protein-Protein Interactions	1.0	null
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
THP1	DepMap CRISPR Gene Dependency	1.0	2.76908
basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.191456
S100A11	Pathway Commons Protein-Protein Interactions	1.0	null
90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03777
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
PMC10290283-biol-2022-0622-sm3.pdf-481-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
MYC	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69005
oral epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.523194
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75601
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069512
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43786
GTF3C4	Pathway Commons Protein-Protein Interactions	1.0	null
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28839
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.308612
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
KEAP1	Pathway Commons Protein-Protein Interactions	1.0	null
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20968
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877722
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.013
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.262
BL9241 (GREB1)	NURSA Protein Complexes	1.0	null
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85126
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937029
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0748
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4054
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2463
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
MCTP2	Pathway Commons Protein-Protein Interactions	1.0	null
C20orf57	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5789
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
CNOT4	Pathway Commons Protein-Protein Interactions	1.0	null
OC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839014
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68416
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08904
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4092
CRCGN015_HEPG2_48H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32662
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59472
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.006
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07517
Hemidesmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
Pleomorphic adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
SRRM1	Pathway Commons Protein-Protein Interactions	1.0	null
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17434
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04189
glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.831966
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.113
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
RAD1	NURSA Protein-Protein Interactions	1.0	1.06443
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
Hydrophthalmos	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00749
LOX	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5213
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46162
AD-18-XC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.788731
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213739
AB-12-IS33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233579
SNU719	DepMap CRISPR Gene Dependency	1.0	2.87613
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973924
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30992
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84313
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08865
ZNF740	Pathway Commons Protein-Protein Interactions	1.0	null
SMTN	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7035
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22534
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29441
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914776
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
NFIL3	Pathway Commons Protein-Protein Interactions	1.0	null
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46843
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79686
ALDH3A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13138
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
DSC1	Pathway Commons Protein-Protein Interactions	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01045
alpha-beta t cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.217511
SHANK2	Pathway Commons Protein-Protein Interactions	1.0	null
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4445
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54865
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835743
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57396
GA-94-MC54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.418958
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908705
QA-81-IM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.49627
Mammary luminal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.676
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.90131
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07028
PMC11257892-Table_1.xlsx-S2-Supplementary_Table_S2_All_results_of_the_preliminary_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1474
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.398931
PCBD1	Pathway Commons Protein-Protein Interactions	1.0	null
AGPAT1	Pathway Commons Protein-Protein Interactions	1.0	null
PPIA	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4390-01A-02R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07578
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2106
MEPCE	Pathway Commons Protein-Protein Interactions	1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
Pwp2p-containing subcomplex of 90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
NCI-H661	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
SEC24B	Pathway Commons Protein-Protein Interactions	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16403
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40045
ZNF714	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17508
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064523
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90454
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11641
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88385
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
g7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
KRT85	Pathway Commons Protein-Protein Interactions	1.0	null
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
JM1	DepMap CRISPR Gene Dependency	1.0	4.16068
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26234
cervical epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521617
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07587
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998014
Amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
SERPINB13	Pathway Commons Protein-Protein Interactions	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8325
Ovarian carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05561
CSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
INSM1	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPH3	Pathway Commons Protein-Protein Interactions	1.0	null
anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.874016
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.547
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54705
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064572
ND-15-RC31_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2056
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.734
RPL36	Pathway Commons Protein-Protein Interactions	1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.068
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081004
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5984
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52081
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397077
b16-f1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
ZNF703	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34724
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94564
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2301
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stratum spinosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1483
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5426
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.817
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
AC-31-PL89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.248559
Endometrial luminal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.612019
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24983
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30293
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32834
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
Scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
Fungal meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04607
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070766
PHLPP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51275
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
BUB1	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MYC	ENCODE Transcription Factor Targets	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
Lung adenocarcinoma_LUAD_TCGA-35-4122-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04787
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1866
PRDX3	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74304
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218621
LXF289	CCLE Cell Line Gene CNV Profiles	1.0	1.55153
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964685
Peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82534
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5114
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1445
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.137
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.428614
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4489
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
DAGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64452
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.756
c-33a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.711
Adult Non-Hodgkin Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM160	Pathway Commons Protein-Protein Interactions	1.0	null
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
496100528_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.29229
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.229024
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.828616
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
18199535-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266203
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15979
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384013
Interstitial lung disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5312
ABCA1	Pathway Commons Protein-Protein Interactions	1.0	null
EZR	Pathway Commons Protein-Protein Interactions	1.0	null
ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.141795
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61513
PMC12036091-jcav16p2321s1.pdf-25-OVOL1_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054428
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89321
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44737
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79686
DRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24981
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.974946
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA12	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.245685
HOXA5_01_305	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.681
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	7.12483
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06497
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
PDIA3	Pathway Commons Protein-Protein Interactions	1.0	null
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12926
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PRPF4	Pathway Commons Protein-Protein Interactions	1.0	null
MELK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56256
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24425
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058727
Gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95734
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915544
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912533
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7583
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58062
increased circulating glycerol level	IMPC Knockout Mouse Phenotypes	1.0	null
TF-29-QU48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28256
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.0516
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082113
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153431
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1233
SERPINB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04188
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868716
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF126	DepMap CRISPR Gene Dependency	1.0	2.43508
Palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
HSPA4	Pathway Commons Protein-Protein Interactions	1.0	null
HOXA10	Pathway Commons Protein-Protein Interactions	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9126
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.440274
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2899
trastuzumab_homo sapiens_gpl6947_gse31432	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SETX	Pathway Commons Protein-Protein Interactions	1.0	null
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1027
CB-62-TB77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.537053
BL6535 (TRAF3IP1)	NURSA Protein Complexes	1.0	null
HSPH1	Pathway Commons Protein-Protein Interactions	1.0	null
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48736
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61617
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCC2	Pathway Commons Protein-Protein Interactions	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Malignant peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
BL6392 (PRKAR2A)	NURSA Protein Complexes	1.0	null
ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122283
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
Histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.26067
SYO1	DepMap CRISPR Gene Dependency	1.0	3.89366
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
BL1020 (FAM184B)	NURSA Protein Complexes	1.0	null
SAMD9L	Pathway Commons Protein-Protein Interactions	1.0	null
Tongue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65014
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
Trophoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
MIB1	Pathway Commons Protein-Protein Interactions	1.0	null
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20856
BL2439 (RBM9)	NURSA Protein Complexes	1.0	null
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
CEP55	Pathway Commons Protein-Protein Interactions	1.0	null
UBB	Pathway Commons Protein-Protein Interactions	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.399
neuroepithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182684
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLD	Pathway Commons Protein-Protein Interactions	1.0	null
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32134
PLOD2	Pathway Commons Protein-Protein Interactions	1.0	null
JUN	Pathway Commons Protein-Protein Interactions	1.0	null
Endometrial glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
sk-n-mc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
H4	CCLE Cell Line Gene CNV Profiles	1.0	1.5305
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
TF	Pathway Commons Protein-Protein Interactions	1.0	null
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886251
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3544
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848293
middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232039
R1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
ENO1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.33625
FNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53885
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992228
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.724
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.40458
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850154
LAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ACOX1	Pathway Commons Protein-Protein Interactions	1.0	null
PRR11	Pathway Commons Protein-Protein Interactions	1.0	null
RPS27L	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.421765
MRPL14	Pathway Commons Protein-Protein Interactions	1.0	null
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92231
CYP2C8	Pathway Commons Protein-Protein Interactions	1.0	null
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11997
ACTC1	Pathway Commons Protein-Protein Interactions	1.0	null
RNA polymerase I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.411
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.283297
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.36179
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2815
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24453
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986668
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
Oral epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Choriocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
RPL14	Pathway Commons Protein-Protein Interactions	1.0	null
SACS	Pathway Commons Protein-Protein Interactions	1.0	null
KCMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.929
ALDOC	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP2R1A	Pathway Commons Protein-Protein Interactions	1.0	null
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33071
MTRF1	Pathway Commons Protein-Protein Interactions	1.0	null
Mammary myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
EWS502	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40313
nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581618
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29155
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55341
CALD1	Pathway Commons Protein-Protein Interactions	1.0	null
TEX10	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.28107
LYRM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.95925
DNAH8	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4885
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
Transcription factor TFIIK complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
Logical memory (immediate recall) in mild cognitive impairment	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
saga complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.421212
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
CTSD	Pathway Commons Protein-Protein Interactions	1.0	null
Parkinson's disease 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
KCNG3	Pathway Commons Protein-Protein Interactions	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
SIPA1L3	Pathway Commons Protein-Protein Interactions	1.0	null
MAST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.174
CRCGN017_MCF10A.WT.HP_24H:C04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16281
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0888
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00602
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879418
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04085
PRDX4	Pathway Commons Protein-Protein Interactions	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978424
uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3539
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.445
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.101003
Stevens-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11714
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31665
MYH2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS17	Pathway Commons Protein-Protein Interactions	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062087
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08722
18794137-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44983
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.849
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09588
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5048
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70302
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95195
EXOSC10	Pathway Commons Protein-Protein Interactions	1.0	null
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.26708
KRT33B	Pathway Commons Protein-Protein Interactions	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	5.19473
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-835-ENSG00000189042_ZNF567	Rummagene Transcription Factor Associations 2026	1.0	null
DHX58	Pathway Commons Protein-Protein Interactions	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6972
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072955
PRRC2C	Pathway Commons Protein-Protein Interactions	1.0	null
PRG4	Pathway Commons Protein-Protein Interactions	1.0	null
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050899
GABARAPL1	Pathway Commons Protein-Protein Interactions	1.0	null
LETM2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73411
AE-14-NN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33983
UTP-C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3902
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18288
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB18	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27056
increased sensitivity to skin irradiation	MGI Mouse Phenotype Associations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.609539
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297038
Transcription factor TFIIH core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
RPL30	Pathway Commons Protein-Protein Interactions	1.0	null
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26079
SRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
Actinic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89388
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09696
Cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29118
Bladder wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
CYP2U1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876618
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71125
histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.177439
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282512
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.791283
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93129
APOBEC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33178
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37141
Verruciform xanthoma of skin	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.75486
vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326432
CLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17059
Cholesteatoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8248
SERPINB3	Pathway Commons Protein-Protein Interactions	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6222
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7507
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
UBA1	Pathway Commons Protein-Protein Interactions	1.0	null
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.626106
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5142
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915755
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13638
HIST1H2BM	Pathway Commons Protein-Protein Interactions	1.0	null
MOV10	Pathway Commons Protein-Protein Interactions	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483206
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51393
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.0189
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05924
TOP2A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52189
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
KRT9	Pathway Commons Protein-Protein Interactions	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91301
AF-12-IW93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269514
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892415
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRAP3	Pathway Commons Protein-Protein Interactions	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886497
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5471
PRKCI	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.296
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88678
BL2785 (PSMC5)	NURSA Protein Complexes	1.0	null
TIA1	Pathway Commons Protein-Protein Interactions	1.0	null
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299812
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3276
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068861
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	2.46026
NRD1	Pathway Commons Protein-Protein Interactions	1.0	null
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23855
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
HCFC2	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINB2	Pathway Commons Protein-Protein Interactions	1.0	null
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09188
RPL36AL	Pathway Commons Protein-Protein Interactions	1.0	null
bacterial-type flagellum basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884525
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066836
NB4	DepMap CRISPR Gene Dependency	1.0	2.13596
496100533_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.12539
TUBG1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7904
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
Uroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.49928
level	GeneRIF Biological Term Annotations	1.0	null
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SYNE1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
RCN2	Pathway Commons Protein-Protein Interactions	1.0	null
S100A7	Pathway Commons Protein-Protein Interactions	1.0	null
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68799
H3F3A	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8415
TEX2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054031
TMPRSS11A	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPA1L2	Pathway Commons Protein-Protein Interactions	1.0	null
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43373
Galactosemias	DisGeNET Gene-Disease Associations	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.98036
CLUH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88994
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8446
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47728
chr19_38786514_A_G_b38	GTEx eQTL 2025	1.0	9.30046
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979188
basal lamina	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21716
DNAJB12	Pathway Commons Protein-Protein Interactions	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3552
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50772
Childhood Non-Hodgkin Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06872
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKI67	Pathway Commons Protein-Protein Interactions	1.0	null
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02413
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210894
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.17501
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
TXN	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sin3-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1888
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47909
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6842
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55914
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901336
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043027
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294781
dermal fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282483
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14431
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21978
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49714
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042789
RUVBL2	Pathway Commons Protein-Protein Interactions	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230382
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50291
Preterm premature rupture of the membranes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9942
CRCGN009_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05016
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KP-N-YS	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
KRT13	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50148
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97083
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Keratinocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072249
HCC1428	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.42115
GNL3	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFHX3	Pathway Commons Protein-Protein Interactions	1.0	null
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01927
Laryngeal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
ENO2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BL8271 (VPS4B)	NURSA Protein Complexes	1.0	null
SFPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
PRPF3	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.15
CHAF1B	Pathway Commons Protein-Protein Interactions	1.0	null
SRSF7	Pathway Commons Protein-Protein Interactions	1.0	null
BD-46-RY02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.528833
Primary cutaneous amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52422
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849413
ATG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98114
PATU8988S	CCLE Cell Line Gene CNV Profiles	1.0	1.46209
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76683
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43833
GSE210101,GSE210114_4_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871625
KRT4	Pathway Commons Protein-Protein Interactions	1.0	null
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.689451
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78373
PCGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58631
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04085
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68985
EZH2	ENCODE Transcription Factor Targets	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08899
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.464
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96355
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35667
NAA38	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
IB-33-TE51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.573749
Proteasome storage granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20346
TDG	Pathway Commons Protein-Protein Interactions	1.0	null
KRT76	Pathway Commons Protein-Protein Interactions	1.0	null
amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317909
NCCRP1	Pathway Commons Protein-Protein Interactions	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81953
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83512
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08907
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
TRPM1	Pathway Commons Protein-Protein Interactions	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.302013
ZC3H18	Pathway Commons Protein-Protein Interactions	1.0	null
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
inverted papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.66914
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_B-pEpi7_B_shared_basaloid_KRT15_TP63_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
IL1B	Pathway Commons Protein-Protein Interactions	1.0	null
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73587
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99501
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042544
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04085
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077937
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089187
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	3.34243
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68617
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29506
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76143
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408972
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77208
15833844-Table2S	GeneSigDB Published Gene Signatures	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8204
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
NME1	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2184
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3507
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24995
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56112
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871214
FD-62-ZB67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.36588
HOP62	DepMap CRISPR Gene Dependency	1.0	2.63264
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03596
GSE48812_7_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC24A	Pathway Commons Protein-Protein Interactions	1.0	null
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8356
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50668
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51249
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.454
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased circulating glycerol level	MGI Mouse Phenotype Associations 2023	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.38558
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15725
BF-10-IO69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.764856
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
18667080-TableS2	GeneSigDB Published Gene Signatures	1.0	null
FZD10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.549
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72633
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.988032
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4435
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953783
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842197
MRGBP	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3661
MAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55889
CNTN5	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT16H	Pathway Commons Protein-Protein Interactions	1.0	null
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22082
RPS21	Pathway Commons Protein-Protein Interactions	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
carcinomas	GeneRIF Biological Term Annotations	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43613
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82427
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.835198
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03181
HECW2	Pathway Commons Protein-Protein Interactions	1.0	null
Childhood Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
CROCC	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06674
Secondary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.615
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85191
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7578
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061553
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22082
TIAL1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12112407-pone.0322130.s001.pdf-97-PLSCR1_PLSCR1	Rummagene Transcription Factor Associations 2026	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190042
weeks	GeneRIF Biological Term Annotations	1.0	null
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23568
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20458
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38959
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963211
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062521
skin	GTEx Tissue Gene Expression Profiles	1.0	2.18897
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.860176
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985309
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
MAST4	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31968
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2916
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervix uteri carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.254
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
RGPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39176
MAGI1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226355,GSE226357_3_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873903
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1219
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850839
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01736
ACACB	Pathway Commons Protein-Protein Interactions	1.0	null
LSM6	Pathway Commons Protein-Protein Interactions	1.0	null
PMC4681751__F1	PFOCR Pathway Figure Associations 2024	1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
Endometrial Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940709
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
SUZ12	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIAA0319	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25339
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
LBX2	Pathway Commons Protein-Protein Interactions	1.0	null
oropharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329361
ATG2A	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64121
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
Gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20233
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73731
NSMAF	Pathway Commons Protein-Protein Interactions	1.0	null
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
Extravillous trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.229
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91212
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
RAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21296
S100A8	Pathway Commons Protein-Protein Interactions	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98037
BL8796 (DAB2IP)	NURSA Protein Complexes	1.0	null
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.09116
KIAA2026	Pathway Commons Protein-Protein Interactions	1.0	null
PML	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5573
BL5049 (POLD3)	NURSA Protein Complexes	1.0	null
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31202
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3048
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964032
EP400	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4717
AGO1	Pathway Commons Protein-Protein Interactions	1.0	null
KCTD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10243
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50816
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.802
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06449
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
tunica intima vasorum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
AP1M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1618
GPR158	Pathway Commons Protein-Protein Interactions	1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	3.73984
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CARM1	Pathway Commons Protein-Protein Interactions	1.0	null
Cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71108
a-REGy (PSME3)	NURSA Protein Complexes	1.0	null
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78851
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38882
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46451
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87885
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7537
H-gal-GP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049298
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5154
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
NCIH661	CCLE Cell Line Gene CNV Profiles	1.0	2.02416
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3198
CLSTN1	Pathway Commons Protein-Protein Interactions	1.0	null
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
NUP98	Pathway Commons Protein-Protein Interactions	1.0	null
Transcription factor TFIIH holo complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67227
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61601
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208574
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82633
DU4475	DepMap CRISPR Gene Dependency	1.0	2.225
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29821
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LRRC15	Pathway Commons Protein-Protein Interactions	1.0	null
ALDH16A1	Pathway Commons Protein-Protein Interactions	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.62991
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0359
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
NPR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
AGO2	Pathway Commons Protein-Protein Interactions	1.0	null
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
KIJK	DepMap CRISPR Gene Dependency	1.0	2.10461
PSMB1	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pre-malignant neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3691
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64174
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174087
Transcription preinitiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968532
PSMB5	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838352
WDR45B	Pathway Commons Protein-Protein Interactions	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
HPRT1	Pathway Commons Protein-Protein Interactions	1.0	null
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
Thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.663
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76161
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627081
skin	HPA Tissue Gene Expression Profiles	1.0	1.82215
Clitoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOP2B	Pathway Commons Protein-Protein Interactions	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986628
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
interstitial cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377402
TPP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43191
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2902
SNRPG	Pathway Commons Protein-Protein Interactions	1.0	null
Hypopharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16874
concentration	GeneRIF Biological Term Annotations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74381
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
mammary myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.937059
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS20	Pathway Commons Protein-Protein Interactions	1.0	null
mammary myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04181
USP1	Pathway Commons Protein-Protein Interactions	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0976
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09978
NCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70518
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04026
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
RPL29	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
POLG	Pathway Commons Protein-Protein Interactions	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.633221
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
XYLT1	Pathway Commons Protein-Protein Interactions	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5203
tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.529608
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23325
PIP	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178577
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
NAP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827372
GABARAPL2	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975535
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
BCLAF1	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878799
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89328
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21159
H2AFX	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9639
EZH2	Pathway Commons Protein-Protein Interactions	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12281
FKBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37352
Perturb_109_KD_FOXC1_SRP276213	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AB-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37353
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07745
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57965
DYNLRB1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3346
ALDH9A1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3409
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20623
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41647
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
TEN	DepMap CRISPR Gene Dependency	1.0	2.42219
RALGAPA1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05853
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCKDHA	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2767
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NOMO2	Pathway Commons Protein-Protein Interactions	1.0	null
NUP210	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
RAB39A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11842
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.3021
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840346
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.722
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915755
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6632
RRP12	Pathway Commons Protein-Protein Interactions	1.0	null
SSR4	Pathway Commons Protein-Protein Interactions	1.0	null
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
SUCLG1	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
OVCAR-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
Mpp10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
FB-98-HM88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265425
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26727
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
Lung adenocarcinoma_LUAD_TCGA-MP-A4SV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC1	Pathway Commons Protein-Protein Interactions	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574416
Oligodendroglioma_CNS - Brain (MMHCC)_GSE2223	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.61977
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253248
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35959
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979468
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071412
TAF2	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.2417
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6309
Extravillous cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63123
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0549
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10306
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9156
RENT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
SMIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21858
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
Keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.016
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47751
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77793
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64977
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	DepMap CRISPR Gene Dependency	1.0	2.31642
Vulvitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Inverted papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10085
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070996
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40991
CIRBP	Pathway Commons Protein-Protein Interactions	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.85541
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23043
RAB15	Pathway Commons Protein-Protein Interactions	1.0	null
who	GeneRIF Biological Term Annotations	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04189
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.526132
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
galectins1	GeneRIF Biological Term Annotations	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4016
decreased keratinocyte migration	MGI Mouse Phenotype Associations 2023	1.0	null
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00014
NCOA7	Pathway Commons Protein-Protein Interactions	1.0	null
CTR9	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypopharyngeal	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50639
Tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
AP4B1	Pathway Commons Protein-Protein Interactions	1.0	null
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61691
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
dld-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368624
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30099
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31031
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.1922
KRT6C	Pathway Commons Protein-Protein Interactions	1.0	null
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.796377
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7449
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19927
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047728
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.67304
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.954856
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1474
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879044
RPL13A	Pathway Commons Protein-Protein Interactions	1.0	null
ALPK3	Pathway Commons Protein-Protein Interactions	1.0	null
HMX2	Pathway Commons Protein-Protein Interactions	1.0	null
BRME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57963
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915755
NA-16-OJ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.489434
BL7766 (MAPK3)	NURSA Protein Complexes	1.0	null
NACA	Pathway Commons Protein-Protein Interactions	1.0	null
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SFN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298524
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49385
GSE189859,GSE189861_3_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077415
common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214636
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13885
gastric adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446
GSN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150072,GSE169209_6_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55199
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26736
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1188
12618198-Table1	GeneSigDB Published Gene Signatures	1.0	null
CTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RANBP6	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14758
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0406
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.839916
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08646
SERPINB4	NURSA Protein-Protein Interactions	1.0	0.310056
Neurilemoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12312
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
PHF20	Pathway Commons Protein-Protein Interactions	1.0	null
PKP1	Pathway Commons Protein-Protein Interactions	1.0	null
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.0138
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.461252
KRT5	Pathway Commons Protein-Protein Interactions	1.0	null
DA-40-HO94_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311018
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59211
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.544
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42377
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.90202
IL16	Pathway Commons Protein-Protein Interactions	1.0	null
BL4184 (USP16)	NURSA Protein Complexes	1.0	null
vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180347
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961552
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14873
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
stratified epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.80768
U2SURP	Pathway Commons Protein-Protein Interactions	1.0	null
CDC26	Pathway Commons Protein-Protein Interactions	1.0	null
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
KIAA1522	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94048
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39872
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81434
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907689
IMR32	DepMap CRISPR Gene Dependency	1.0	2.30021
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057141
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL33	DepMap CRISPR Gene Dependency	1.0	2.13489
C-33A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8302
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23726
19351829-Table1	GeneSigDB Published Gene Signatures	1.0	null
MKL1	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05074
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
DENND6B	Pathway Commons Protein-Protein Interactions	1.0	null
Uterus carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.36611
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76489
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946191
Lung squamous cell carcinoma_LUSC_TCGA-33-4547-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16442_KD_IL13RA2_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
nm95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
Epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mRNA cleavage stimulating factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12989
MTMR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56611
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34139
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44938
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91629
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.7
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.36138
CAPRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847073
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20782
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
Acne	DisGeNET Gene-Disease Associations	1.0	null
APOBEC3B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84424
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4423
Carcinoma Breast	DisGeNET Gene-Disease Associations	1.0	null
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
ovarian serous cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.974642
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32158
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18751
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07918
RPN1	Pathway Commons Protein-Protein Interactions	1.0	null
NIPSNAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
Placental disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.124107
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	2.39859
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32048
CAPZB	Pathway Commons Protein-Protein Interactions	1.0	null
Secondary Malignant Neoplasm Of Axilla	DisGeNET Gene-Disease Associations	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KATO-III cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81829
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49899
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
venous endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.336704
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0981
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ascus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.253
seen	GeneRIF Biological Term Annotations	1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930126
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040762
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395281
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3191
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43441
BL4037 (CORO1A)	NURSA Protein Complexes	1.0	null
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CF-24-KQ98_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.359607
HELLP syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
BF-10-IO69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.687996
Basal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.11421
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4795
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
CDK2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11063
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.093369
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154047
KRT14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48002
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.885171
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975535
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19873
YAF2	Pathway Commons Protein-Protein Interactions	1.0	null
PPP2R3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88784
skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.473361
CRCGN009_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03198
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.2081
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7904
Ovarian serous cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
gastric cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14699
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5284
MUC3A	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6493
PANC1	CCLE Cell Line Gene CNV Profiles	1.0	2.22841
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10225
cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
YTHDC2	Pathway Commons Protein-Protein Interactions	1.0	null
malignant ovarian surface epithelial-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.143707
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49622
HSPA7	Pathway Commons Protein-Protein Interactions	1.0	null
IGHM	Pathway Commons Protein-Protein Interactions	1.0	null
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
Cryptococcal meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
CARD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49425
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.488
KIF12	Pathway Commons Protein-Protein Interactions	1.0	null
CHST10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60999
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2419
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3684
SMYD4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895145
bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166544
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95729
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76886
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3A	Pathway Commons Protein-Protein Interactions	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.541773
KP-1N	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8356_KO_HKDC1_SRP346010	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
Adult Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
KRT17	Pathway Commons Protein-Protein Interactions	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977251
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
BAHCC1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL11	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11119
MCM4	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45358
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204107
t cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.132033
KRT77	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16572
MTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04865
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25939
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
BB-44-SX65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203396
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054892
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.24
squamous	GeneRIF Biological Term Annotations	1.0	null
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88968
ESR1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
CDC42EP1	Pathway Commons Protein-Protein Interactions	1.0	null
protein-cysteine S-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2589
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40172
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4706
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37573
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365859
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
HNRNPUL1	Pathway Commons Protein-Protein Interactions	1.0	null
CLEC11A	Pathway Commons Protein-Protein Interactions	1.0	null
DC-93-NP78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3111
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09184
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Follicular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08814
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.351382
WDR11	Pathway Commons Protein-Protein Interactions	1.0	null
TENM2	Pathway Commons Protein-Protein Interactions	1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	258.182
Glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
Uterine endometrial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
PRDX1	Pathway Commons Protein-Protein Interactions	1.0	null
TASK1	DepMap CRISPR Gene Dependency	1.0	2.85121
DDX3Y	Pathway Commons Protein-Protein Interactions	1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.539
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5857
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
ID-00-IC14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.26118
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061647
ZC3H7B	Pathway Commons Protein-Protein Interactions	1.0	null
AGL	Pathway Commons Protein-Protein Interactions	1.0	null
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27205
TROVE2	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21159
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51535
PSMA6	Pathway Commons Protein-Protein Interactions	1.0	null
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.479
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907468
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357172
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.532314
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.805
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
PGAM2	Pathway Commons Protein-Protein Interactions	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
TGM1	Pathway Commons Protein-Protein Interactions	1.0	null
Swr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
ZNF512B	Pathway Commons Protein-Protein Interactions	1.0	null
WBP2	Pathway Commons Protein-Protein Interactions	1.0	null
oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244545
BL773 (TREX1)	NURSA Protein Complexes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989021
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113009
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97157
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.340855
chr19_38770268_C_G_b38	GTEx eQTL 2025	1.0	1.59416
RPL21	Pathway Commons Protein-Protein Interactions	1.0	null
corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.502357
FD-62-ZB67_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.414759
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
Endoplasmic reticulum palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.102
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gastric cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138361
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
JHH5	DepMap CRISPR Gene Dependency	1.0	2.03905
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8456
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
FZR1	Pathway Commons Protein-Protein Interactions	1.0	null
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.28999
PRKAR1B	Pathway Commons Protein-Protein Interactions	1.0	null
hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326432
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32662
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10293
ADNP	Pathway Commons Protein-Protein Interactions	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
keratinocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18068
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
MATN4	Pathway Commons Protein-Protein Interactions	1.0	null
PDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09338
corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.506279
BL3241 (DHX29)	NURSA Protein Complexes	1.0	null
PMC4681751__F1	PFOCR Pathway Figure Associations 2023	1.0	null
HSPA1L	Pathway Commons Protein-Protein Interactions	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946048
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11837
adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326067
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.27513
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.915755
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
AGFG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37219
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19348
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
S100A9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.748
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959267
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41077
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.202
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0
BL6346 (ATF2)	NURSA Protein Complexes	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3624
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85846
GD-82-CS38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.227162
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11366
AKR7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76061
NCI-H1299	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
S100A8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.455
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8488
AIFM2	Pathway Commons Protein-Protein Interactions	1.0	null
LGALS1	Pathway Commons Protein-Protein Interactions	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060675
MED12L	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0674
ANLN	Pathway Commons Protein-Protein Interactions	1.0	null
Cervix carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42038
Cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052793
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GFPT1	Pathway Commons Protein-Protein Interactions	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052808
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9383
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.748
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45314
ECH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24605
DKKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93193
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33031
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.714619
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.149
Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.744
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12886
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870915
ATAD3A	Pathway Commons Protein-Protein Interactions	1.0	null
RPL13	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.49735
Decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
CKB	Pathway Commons Protein-Protein Interactions	1.0	null
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55461
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60253
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.489
Basal-Like Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15173_KO_PTPN14_SRP167101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.20506
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81351
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046408
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34371
NUDT1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8593
TOP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2	Pathway Commons Protein-Protein Interactions	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56461
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00015
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
LCN12	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	Pathway Commons Protein-Protein Interactions	1.0	null
ERP44	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09558
oral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489057
NUDT21	Pathway Commons Protein-Protein Interactions	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
Retinal arterial tortuosity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39232
Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
RRM1	Pathway Commons Protein-Protein Interactions	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051711
LD-39-FL02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230584
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0883
goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128086
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00538
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.89482
Uroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.543
PFKFB1	NURSA Protein-Protein Interactions	1.0	1.06443
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41803
TRIP12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88897
Phosphorylase kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46011
GPC6	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
PRPH	Pathway Commons Protein-Protein Interactions	1.0	null
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
TNR	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834727
DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
DDX24	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.988466
KANK2	Pathway Commons Protein-Protein Interactions	1.0	null
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130732
SiHa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
ZNF764	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32727
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A10	Pathway Commons Protein-Protein Interactions	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.459
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.16352
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.434684
nodular goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.445805
ADAMTS20	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H2AB	Pathway Commons Protein-Protein Interactions	1.0	null
Stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
cervical epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827372
Villous cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2614
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227707
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16458
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7737
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Vulvar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
BL1097 (DYRK3)	NURSA Protein Complexes	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07117
Urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23497
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3728
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
Cryptococcosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79591
Chagas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Amniochorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
HK1	Pathway Commons Protein-Protein Interactions	1.0	null
MAP7D1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preeclampsia	GeneRIF Biological Term Annotations	1.0	null
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
BL5254 (TAF3)	NURSA Protein Complexes	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1959
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55384
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.357086
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.862443
GSE153871_0_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FASTKD1	Pathway Commons Protein-Protein Interactions	1.0	null
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9615
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HLA-DQB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3436
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04845
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71274
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246919
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6207
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.879074
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
N-terminal protein acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4252
CNOT11	Pathway Commons Protein-Protein Interactions	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2816
C2orf16	Pathway Commons Protein-Protein Interactions	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.74496
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.753703
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86345
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LUZP1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.12189
NCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
GPI-anchor transamidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56084
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.242945
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34667
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57505
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.135
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25593
Galectin lattice	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7253
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
DDX27	Pathway Commons Protein-Protein Interactions	1.0	null
Transcription export complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
TRAK1	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03685
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066445
CB-30-KN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.30563
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60124
BL2157 (USP34)	NURSA Protein Complexes	1.0	null
DNAJB1	Pathway Commons Protein-Protein Interactions	1.0	null
BL7201 (EPS8L2)	NURSA Protein Complexes	1.0	null
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.77394
oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.305226
PFDN2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
TCF3	Pathway Commons Protein-Protein Interactions	1.0	null
FN1	Pathway Commons Protein-Protein Interactions	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042836
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60916
SM-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
KMT2A	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB40	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05707
CRCGN011_HEPG2_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19865
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.04
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066836
RUNX2	Pathway Commons Protein-Protein Interactions	1.0	null
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82167
Mammary myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063524
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076875
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
PDZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8817
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Basal cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.114954
POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
GYG1	Pathway Commons Protein-Protein Interactions	1.0	null
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.525106
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302118
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
KRT34	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894834
ABCB1	Pathway Commons Protein-Protein Interactions	1.0	null
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95936
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.71855
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8258
KRT10	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51942
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.8824
Oral cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.0958
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0059
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098357
ATP5L	Pathway Commons Protein-Protein Interactions	1.0	null
LRP1B	Pathway Commons Protein-Protein Interactions	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057874
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256233
CB-32-EI69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300385
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.479
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76423
OTUD4	Pathway Commons Protein-Protein Interactions	1.0	null
RPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28041
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19851
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32399
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45661
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BL5529 (CCDC99)	NURSA Protein Complexes	1.0	null
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39416
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33004
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3404
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855955
BL7759 (ABCC4)	NURSA Protein Complexes	1.0	null
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044608
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
PRPF38B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10797
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83351
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.976323
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL2268 (TDP1)	NURSA Protein Complexes	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871496
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04189
IGHG2	Pathway Commons Protein-Protein Interactions	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
ETV6	Pathway Commons Protein-Protein Interactions	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.463261
MYH4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39001
Rpd3S/Clr6-CII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
USP10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226285_3_v_1_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2817_KD_SASH1_SRP231434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.1964
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05801
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29821
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SQRDL	Pathway Commons Protein-Protein Interactions	1.0	null
Gingival fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5871
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.638
CRCGN015_MCF10A.TP53.M_24H:C16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00895
Radicular Cyst	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.37615
MUC5AC	Pathway Commons Protein-Protein Interactions	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
TENM3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.25
HSPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60589
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.398357
PDLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
17409405-Table1a	GeneSigDB Published Gene Signatures	1.0	null
TRA2A	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF567	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11474
RPL7	Pathway Commons Protein-Protein Interactions	1.0	null
SEC24C	Pathway Commons Protein-Protein Interactions	1.0	null
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048454
BL5947 (ZNRF2)	NURSA Protein Complexes	1.0	null
CHD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68981
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21689
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
SK-N-MC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18598
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19648
SNRPF	Pathway Commons Protein-Protein Interactions	1.0	null
THEM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13044
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3512
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.4676
Esophageal basaloid squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.564
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167943
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3277
YWHAZ	Pathway Commons Protein-Protein Interactions	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79221
AJAP1	Pathway Commons Protein-Protein Interactions	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22082
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39699
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41681
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.184
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
IGKV1-5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01331
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.453836
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05666
TRIP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23075
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1152
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852559
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10633
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.2876
VPS13D	Pathway Commons Protein-Protein Interactions	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7195
QPCT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7618
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59177
peripheral nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.409731
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85115
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	4.06762
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16352
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1072
KRT16	Pathway Commons Protein-Protein Interactions	1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09625
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7386-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046559
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.799068
Vulva carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DNAJC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57586
PD-94-WO47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374106
S100A9	Pathway Commons Protein-Protein Interactions	1.0	null
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78441
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1474
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1912
DSG1	Pathway Commons Protein-Protein Interactions	1.0	null
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1809
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71959
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07234
HNRNPH2	Pathway Commons Protein-Protein Interactions	1.0	null
BL7244 (MAST4)	NURSA Protein Complexes	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8546
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078648
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36705
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48288
WDR48	Pathway Commons Protein-Protein Interactions	1.0	null
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74303
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20837
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47271
CALML3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
oral squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82801
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0626-SM-4DM5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832743
DACT1	Pathway Commons Protein-Protein Interactions	1.0	null
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
HIST2H2BE	Pathway Commons Protein-Protein Interactions	1.0	null
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04468
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17141
SAMHD1	Pathway Commons Protein-Protein Interactions	1.0	null
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00714
RBM10	Pathway Commons Protein-Protein Interactions	1.0	null
IDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24229
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62777
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12501
THEM6	Pathway Commons Protein-Protein Interactions	1.0	null
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
H2AFZ	Pathway Commons Protein-Protein Interactions	1.0	null
RPS26	Pathway Commons Protein-Protein Interactions	1.0	null
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72508
DIRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.17
ACTBL2	Pathway Commons Protein-Protein Interactions	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
USP36	Pathway Commons Protein-Protein Interactions	1.0	null
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
SEC11C	Pathway Commons Protein-Protein Interactions	1.0	null
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10552
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2601
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081873
Chorionic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079959
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42233
MAP3K3	Hub Proteins Protein-Protein Interactions	1.0	null
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MIF	Pathway Commons Protein-Protein Interactions	1.0	null
Head and neck squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
DCHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45654
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048932
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64728
EEF1B2	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9134
SNU216	DepMap CRISPR Gene Dependency	1.0	3.52955
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5436
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
GA-47-MH68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.585442
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
ITGAL	Pathway Commons Protein-Protein Interactions	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4879
neoplastic	GeneRIF Biological Term Annotations	1.0	null
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86877
FLG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155836,GSE155839_3_v_1_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXC2	Pathway Commons Protein-Protein Interactions	1.0	null
PD-94-WO47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.652675
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40899
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8699
NPTX2	Pathway Commons Protein-Protein Interactions	1.0	null
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.882
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07067
DC-84-GJ21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.386919
MDH2	Pathway Commons Protein-Protein Interactions	1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3754
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0382
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59092
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
ARHGAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89471
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0443
KATOIII	DepMap CRISPR Gene Dependency	1.0	2.13412
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7471
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80167
AMPD1	Pathway Commons Protein-Protein Interactions	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066511
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
Spinocerebellar ataxia type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46291
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRPF39	Pathway Commons Protein-Protein Interactions	1.0	null
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1607
brain	GTEx Tissue Gene Expression Profiles	-1.0	-0.97439
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86478
NEDD4	Pathway Commons Protein-Protein Interactions	1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	2.8125
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26288
DGAT2L7P	Pathway Commons Protein-Protein Interactions	1.0	null
OB-17-DQ74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.459603
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75634
FLCN	Pathway Commons Protein-Protein Interactions	1.0	null
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.13409
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827746
PPIP5K2	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.991748
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55022
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.567
chr19_38768934_C_G_b38	GTEx eQTL 2025	1.0	1.14064
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32941
Cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66897
rtg2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0751
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
MAPKAPK2	Pathway Commons Protein-Protein Interactions	1.0	null
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88593
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.855955
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14694
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02244
SNRPB	Pathway Commons Protein-Protein Interactions	1.0	null
PPP2R3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CX-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83569
Vulvar Lichen Sclerosus	DisGeNET Gene-Disease Associations	1.0	null
SNRPC	Pathway Commons Protein-Protein Interactions	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6359
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NA-16-OJ70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285699
AP1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70495
AA-68-OJ16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241423
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62396
presence	GeneRIF Biological Term Annotations	1.0	null
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333396
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11628
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.90015
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20425
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2286	DepMap CRISPR Gene Dependency	1.0	2.66384
Mitochondrial prohibitin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.646505
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27865
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07293
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408972
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2522
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6641
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.852225
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06396
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5598
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67503
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331147
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.32691
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9265
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
saga-type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.356324
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.895
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14677
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
Carcinoma Of Bladder	DisGeNET Gene-Disease Associations	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.749644
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903606
Oral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
ABI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36399
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4309
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4113
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913854
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5949
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.95026
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
Bladder Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
SBNO2	Pathway Commons Protein-Protein Interactions	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
ADSL	Pathway Commons Protein-Protein Interactions	1.0	null
RPL10L	Pathway Commons Protein-Protein Interactions	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1294
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848013
CBFB	Pathway Commons Protein-Protein Interactions	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871496
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
GSE226285_3_v_1_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
KALRN	Pathway Commons Protein-Protein Interactions	1.0	null
RPP30	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KRT6B	Pathway Commons Protein-Protein Interactions	1.0	null
RIMS2	Pathway Commons Protein-Protein Interactions	1.0	null
PRPF31	Pathway Commons Protein-Protein Interactions	1.0	null
ARID5B	Pathway Commons Protein-Protein Interactions	1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	2.78612
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH460	DepMap CRISPR Gene Dependency	1.0	2.1221
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12514
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914776
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53568
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10934
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84435
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7275
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.611
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29354
chr19_38769949_C_G_b38	GTEx eQTL 2025	1.0	2.20965
goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342233
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.586
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.886418
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
BE-04-AN21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.414108
Eye-t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.134051
skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063249
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03684
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
PATU8988T	CCLE Cell Line Gene CNV Profiles	1.0	1.77734
SNRPE	Pathway Commons Protein-Protein Interactions	1.0	null
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
RBM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57458
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05338
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
A-2780 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
Corm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6336
8MGBA	DepMap CRISPR Gene Dependency	1.0	3.77834
RPL18A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6463
BL3564 (CDK5RAP3)	NURSA Protein Complexes	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7336
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53528
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95599
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73419
subsequently	GeneRIF Biological Term Annotations	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60108
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20947
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16721
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50148
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.531928
HSCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35001
CBC641 (CC2D1B)	NURSA Protein Complexes	1.0	null
hypopharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.901978
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.286451
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84424
A549	CCLE Cell Line Gene CNV Profiles	1.0	1.58211
RPL27	Pathway Commons Protein-Protein Interactions	1.0	null
NAIP	Pathway Commons Protein-Protein Interactions	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101509
keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212945
S100A16	Pathway Commons Protein-Protein Interactions	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953031
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10194
t-UTP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.87
ADGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69737
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43298
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24976
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
gastric adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22415
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01638
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1882
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10255
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.748
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.827372
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07366
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10058
RAG1	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PELP1	Pathway Commons Protein-Protein Interactions	1.0	null
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04284
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
BC-40-TU13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.84648
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88766
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
FADS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17728
FANCM	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91692
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27191
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165071
Borst-Jadassohn intraepidermal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01863
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1681
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05942
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.863505
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1408
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03235
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837568
BeWo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Erythema multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440671
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
Thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
transferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054517
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73364
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9618
JR	DepMap CRISPR Gene Dependency	1.0	2.05237
ACADM	Pathway Commons Protein-Protein Interactions	1.0	null
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31068
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.19003
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15366
BB-72-TP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.638777
RPL37A	Pathway Commons Protein-Protein Interactions	1.0	null
UQCRFS1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.646467
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GMP reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.391679
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844349
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13951
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.42637
FERMT3	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8346
BA-68-FJ41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.356149
ACACA	Pathway Commons Protein-Protein Interactions	1.0	null
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188398
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02448
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95425
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24191
Squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20992
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAV3	Pathway Commons Protein-Protein Interactions	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99469
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043601
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
RTN4RL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36192
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.34627
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71153
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2265
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
RBMXL2	Pathway Commons Protein-Protein Interactions	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.271
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16377
KIAA0922	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Integument	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.0621
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
RDX	Pathway Commons Protein-Protein Interactions	1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3569
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13959
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPIH	Pathway Commons Protein-Protein Interactions	1.0	null
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
ATG4B	Pathway Commons Protein-Protein Interactions	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.245685
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190821
Tongue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99488
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
Oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell-cell adhesion via plasma-membrane adhesion molecules	GO Biological Process Annotations 2025	1.0	null
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
PWP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13273
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARFGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SHE	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
SNU1041	DepMap CRISPR Gene Dependency	1.0	2.98548
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
MDA-MB-453 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
actinic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.500379
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891614
Epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.084
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9899
GE-98-ZI68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396353
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
siha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
S-49 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
SERPINB3	NURSA Protein-Protein Interactions	1.0	0.066693
Integrin alpha1-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
Gastric pit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFAP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82568
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179239
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.985
RNA polymerase II, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28756
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07578
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10179
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
Nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.424
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.58
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6477
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
RBFOX2	Pathway Commons Protein-Protein Interactions	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43789
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15308
SELENBP1	Pathway Commons Protein-Protein Interactions	1.0	null
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.26925
ERBB2IP	Pathway Commons Protein-Protein Interactions	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9551
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221291
STAT3_01_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.4088
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
KLE	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
Rheumatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	GO Biological Process Annotations 2025	1.0	null
NIF3L1	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH322	DepMap CRISPR Gene Dependency	1.0	2.4782
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	2.57893
PLOD3	Pathway Commons Protein-Protein Interactions	1.0	null
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21159
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5441
EPC1	Pathway Commons Protein-Protein Interactions	1.0	null
496100285_TCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11556
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
SPATA5L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48731
SNU-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
GSE216757_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41897
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0408
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39395
IMMT	Pathway Commons Protein-Protein Interactions	1.0	null
GYS1	Pathway Commons Protein-Protein Interactions	1.0	null
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28921
CRCGN015_MCF10A.TP53.M_24H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01865
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47384
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
cholesteatoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.433021
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0334
PSMD11	Pathway Commons Protein-Protein Interactions	1.0	null
PSMA3	Pathway Commons Protein-Protein Interactions	1.0	null
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.650508
GFI1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92993
INSIG2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1667
Epithelial Ovarian Cancer	DisGeNET Gene-Disease Associations	1.0	null
AB-74-VK99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.722986
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39808
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
ABCA9	Pathway Commons Protein-Protein Interactions	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215136
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
VTN	Pathway Commons Protein-Protein Interactions	1.0	null
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2248
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBR1	Pathway Commons Protein-Protein Interactions	1.0	null
PGD	Pathway Commons Protein-Protein Interactions	1.0	null
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
GEMIN5	Pathway Commons Protein-Protein Interactions	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.1576
SGOL2	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2227	CCLE Cell Line Gene CNV Profiles	1.0	2.48871
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9181
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1347
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
HEC59	DepMap CRISPR Gene Dependency	1.0	2.8547
PCYT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17615
SNU719	CCLE Cell Line Gene CNV Profiles	1.0	1.56266
DB-88-VW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.322912
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82138
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03346
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93793
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31116
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	230.061
EW8	CCLE Cell Line Gene CNV Profiles	1.0	1.85947
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82633
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78963
cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261964
STBD1	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486326
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188274
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82534
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.941189
trophoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335968
CRCGN017_MCF10A.WT.HP_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4322
DOK1	Pathway Commons Protein-Protein Interactions	1.0	null
SUCLG2	Pathway Commons Protein-Protein Interactions	1.0	null
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10334
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7309
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ST6GALNAC6	Pathway Commons Protein-Protein Interactions	1.0	null
CAD	Pathway Commons Protein-Protein Interactions	1.0	null
UBTF	Pathway Commons Protein-Protein Interactions	1.0	null
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
Oral mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
PADI2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10174
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.883655
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57565
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13908
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9848
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995315
LGALS3BP	Pathway Commons Protein-Protein Interactions	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0388
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12165
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94216
RNA polymerase II, holoenzyme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
FA-39-KG56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.276982
melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066346
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.419252
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64395
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954871
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPLAD1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088618
progesterone-receptor negative breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
PSMB2	Pathway Commons Protein-Protein Interactions	1.0	null
ARID4B	Pathway Commons Protein-Protein Interactions	1.0	null
PRRC2A	Pathway Commons Protein-Protein Interactions	1.0	null
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090914
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
SARS-ddORF6_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.62285
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216714
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	1.83859
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
DE-98-FC24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.266182
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159256
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
YD10B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34413
EXOSC1	Pathway Commons Protein-Protein Interactions	1.0	null
Laryngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40287
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873394
Epithelial ovarian cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45891
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20646
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13638
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.332
DIP2B	Pathway Commons Protein-Protein Interactions	1.0	null
SC-48849 (BRE)	NURSA Protein Complexes	1.0	null
PMC11657369-12951_2024_3025_MOESM2_ESM.xlsx-PC-3-NR2F1-AS1-pulldown-Gene_names_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916684
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24527
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.9862
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99684
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999215
ECH1	Pathway Commons Protein-Protein Interactions	1.0	null
PALD1	Pathway Commons Protein-Protein Interactions	1.0	null
AHNAK2	Pathway Commons Protein-Protein Interactions	1.0	null
USP4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_2_KD_HeLa-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Rpd3L complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78729
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214527
ELFN1	Pathway Commons Protein-Protein Interactions	1.0	null
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
SNX19	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN011_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13345
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CX-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.553
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345542
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPSF2	Pathway Commons Protein-Protein Interactions	1.0	null
larynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9104
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40166
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890292
myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565232
precuneus, left, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21687
SMARCA5	Pathway Commons Protein-Protein Interactions	1.0	null
VSIG8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148321,GSE169423_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9124
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
Ovary epithelial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19293
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997376
DPM1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL6	Pathway Commons Protein-Protein Interactions	1.0	null
Systemic scleroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.25546
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5269
ZNF541	Pathway Commons Protein-Protein Interactions	1.0	null
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77849
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301398
YD15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42991
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143333
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.971
RPLP1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39591
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
BRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	218.882
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75504
BPTF	Pathway Commons Protein-Protein Interactions	1.0	null
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.253
GSE213228_1_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GCIY	COSMIC Cell Line Gene CNV Profiles	1.0	2.08334
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
SDHB	Pathway Commons Protein-Protein Interactions	1.0	null
MAP3K7	Pathway Commons Protein-Protein Interactions	1.0	null
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
PSEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42544
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93445
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13455
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
WDR18	Pathway Commons Protein-Protein Interactions	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53167
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5907
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557661
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25466
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333396
BE-31-XV38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.80397
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925599
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45213
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
MFHAS1	Pathway Commons Protein-Protein Interactions	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851138
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
WIPF1	Pathway Commons Protein-Protein Interactions	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01354
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4144
GSE180525,GSE180528_1_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41146
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04085
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29915
inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218398
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.393
C18orf32	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870732
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02268
serum	GeneRIF Biological Term Annotations	1.0	null
CDK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0649
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07088
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.303781
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44743
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10293
oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446