association dataset threshold value standardized value H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3158-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Perturb_7748_KD_HRSP12_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.59428 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal mechanoreceptor morphology MPO Gene-Phenotype Associations 1.0 null PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null SCS214 DepMap CRISPR Gene Dependency 1.0 4.52808 Perturb_14561_KD_UBE2C_SRP221206 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.26351 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.691094 POLR2A ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7280_KO_CASC3_ERP118046 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16892 Perturb_16467_KO_Ncstn_SRP149348 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.61175 GSE196117_6_v_8_clarithromycin_human RummaGEO Drug Perturbation Signatures 1.0 null X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67328 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2922 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.962316 Nasal squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 Retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.327 SFTPC_KO_GDS4876_476_mouse_Lung Type II cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_7496_KD_EFTUD2_SRP192094 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.146 FOXP1 ChEA Transcription Factor Targets 1.0 null SOX2 ChEA Transcription Factor Targets 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59003 hsa-miR-3689b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1864 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null one GeneRIF Biological Term Annotations 1.0 null SCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01903 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33064 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_9935_KD_ATP5F1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.27038 COR-L95 COSMIC Cell Line Gene Mutation Profiles 1.0 null cochlear hair cell degeneration MPO Gene-Phenotype Associations 1.0 null Perturb_12910_KD_FOXA1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.13813 Autosomal recessive nonsyndromic deafness 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.803 SMAD3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9666_Mut_NR1H4_SRP115904 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.98286 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.990429 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2681_KD_TEAD4_SRP181909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.53044 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.554938 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05896 membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.003506 Perturb_8839_KD_WDR5_SRP258987 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.2028 ICC137 DepMap CRISPR Gene Dependency 1.0 2.00166 ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02844 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal neuron morphology MPO Gene-Phenotype Associations 1.0 null mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.980532 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_269_KD_SNIP1_SRP322020 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.18946 Hinge joint TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.562 496100618_PCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13862 GSE146982_7_v_5_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE131649_6_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null sensory system disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal dominant nonsyndromic deafness 25 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.823 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49269 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08581 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.831966 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.928 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6891 Perturb_8881_KD_CSL_SRP142324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.69705 PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_10036_KD_PUM2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.04943 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.05536 Basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null NUGC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null small intestine HPA Tissue Protein Expression Profiles 1.0 1.10979 OVCA420 DepMap CRISPR Gene Dependency 1.0 2.98311 Perturb_10015_KD_HNRNPC_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 TUBG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10809 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null photosystem i COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.198658 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.826443 SIN3A ENCODE Transcription Factor Targets 1.0 null abnormal behavior MPO Gene-Phenotype Associations 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null Vestibular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.969 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.728858 HDAC2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1143 DepMap CRISPR Gene Dependency 1.0 3.4781 Perturb_10355_KD_SHQ1_SRP154234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.0353 SYO1 DepMap CRISPR Gene Dependency 1.0 3.3742 rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Autosomal dominant nonsyndromic deafness 17 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.507 TMEM187 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8381 impaired swimming MPO Gene-Phenotype Associations 1.0 null Deafness DisGeNET Gene-Disease Associations 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_9883_KD_CPEB4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.10483 cochlear inner hair cell degeneration MGI Mouse Phenotype Associations 2023 1.0 null High light scatter reticulocyte count GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0 primary auditory cortex (core)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.94767 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913774 ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42847 Perturb_16482_KO_Irf6_SRP173804 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.5454 mediodorsal nucleus of thalamus_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.903283 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980728 brain cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232881 Perturb_8283_KD_BCLAF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.35317 MTHFSD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0201 Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7460_KD_UPF3B_SRP120604 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.767 Perturb_8193_KD_PPIL4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.91654 Perturb_10120_KO_RNH1_ERP021688 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.42614 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051349 Perturb_10351_KO_NSD2_SRP229726 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.6236 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01827 rt1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.989 REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null sensorineural hearing impairment HPO Gene-Disease Associations 1.0 null TAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0038 MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.47854 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00787 ZNF408 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0465 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE196117_1_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures 1.0 null Cuticular plate COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.371 sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.349717 REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null Perturb_9286_KD_LMTK2_SRP276928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.36465 496100337_HIP_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.00204 inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.300533 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.918078 Perturb_10051_KD_PRPF8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.94588 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08396 AQR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37238 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02397 Perturb_11435_KD_CIT_SRP173646 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.98335 Perturb_1068_OE_PHF19_SRP188592 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.75705 Perturb_11562_KD_BAX/BAK_SRP348085 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02366 Perturb_6840_KD_lncLUCRC_SRP218870 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.27527 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EJM CCLE Cell Line Gene CNV Profiles 1.0 1.72483 Nonsyndromic deafness DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 GSE199874_4_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25437 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2124 detection of mechanical stimulus GO Biological Process Annotations 2025 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.6059 pellicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.588875 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69039 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43172 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9939_KD_KIF1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.37602 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.955451 GSE244710_3_v_2_srsf1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_16954_KO_MLX_SRP183152 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.80868 MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.1741 ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal dominant nonsyndromic deafness 22 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.008 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958562 head tossing MPO Gene-Phenotype Associations 1.0 null Perturb_10251_KO_WT1_ERP126063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.60902 UACC893 DepMap CRISPR Gene Dependency 1.0 2.1222 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.33039 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73894 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.501965 Sensory system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 GPR120_KO_GDS4830_413_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE148010,GSE148120_3_v_2_tet2_human RummaGEO Gene Perturbation Signatures 1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-BRCA_AND_UCEC_NOT_CESC_NOT_UCS_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.68134 impaired balance MPO Gene-Phenotype Associations 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.986084 PMC12540438-Data_Sheet_1.PDF-20-ENSG00000189164_ZNF527 Rummagene Transcription Factor Associations 2026 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3656_KO_MTHFD1_SRP120974 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_629_KO_SOX4_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.94245 intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.082473 Autosomal recessive nonsyndromic deafness 91 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.413 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Br_Thermoneutral_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041537 FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3148 PATU8988T DepMap CRISPR Gene Dependency 1.0 2.59382 neurological system process GO Biological Process Annotations 2015 1.0 null GSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6869 Perturb_754_OE_METTL3_SRP393226 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.0068 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8764_KD_SLIT2_SRP158939 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.63692 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.5919 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.51662 Perturb_7159_KD_ACTG1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.9684 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null 647V CCLE Cell Line Gene CNV Profiles 1.0 1.63805 USF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19076 Perturb_12951_KD_ALKBH5_SRP247667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.10228 astroglial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.125865 Perturb_7490_KD_SIN3B_SRP173465 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.42352 SUCLA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41928 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.952438 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.831966 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.887985 eye and adnexa disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.270108 OCILY19 DepMap CRISPR Gene Dependency 1.0 4.07159 cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.284962 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NB10 DepMap CRISPR Gene Dependency 1.0 2.21066 Uterus GTEx Tissue Gene Expression Profiles 2023 1.0 5.68826 THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.0817 endomembrane system COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.207794 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.851321 CDK4_knockdown_143_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.96076 Autosomal dominant nonsyndromic deafness 2B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051959 Upper tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.514 CREM JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2938 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null LSM14A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15428 PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.938271 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.878514 Myosin VI complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.139 cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.370067 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2961 HCFC1 ENCODE Transcription Factor Targets 1.0 null Perturb_14611_KO_MTAP_SRP186070 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.4318 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6616_KO_NEUROD1_SRP388830 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_7444_KD_LOC550643_SRP096253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.06514 Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 Perturb_7912_KO_RNPC3_SRP367036 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.7675 Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.139 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stereocilium shaft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.122 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51273 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3963_KO_PTPN2_SRP108032 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.81792 Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8552 inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43883 inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33972 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00881 Perturb_9285_KD_LMTK2_SRP276928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.0746 Perturb_8819_KD_TRRAP_SRP106050 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.55016 Perturb_7623_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.94017 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.6623 SNU1214 CCLE Cell Line Gene CNV Profiles -1.0 -2.57628 S462 DepMap CRISPR Gene Dependency 1.0 2.18656 NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2336 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824608 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949524 TMEM88B_KD_GPL10558_471_human_cardiovascular progenitors cells differentiated from hES cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CCNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24076 CBX3 ENCODE Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.971882 Perturb_10059_KD_XRN2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.78847 mode of inheritance HPO Gene-Disease Associations 1.0 null intestinal volvulus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.99908 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D1FED24h_vs_D1FAST24h_259_AR-DE-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2522 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12232_KD_SNRPA1_SRP291357 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.06311 Perturb_7764_KD_RRP40_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.8725 GSE203485_1_v_0_zdhhc2_human RummaGEO Gene Perturbation Signatures -1.0 null Stereocilium tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.279 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924786 Autosomal recessive nonsyndromic hearing loss ClinVar Gene-Phenotype Associations 2025 1.0 null IMR32 DepMap CRISPR Gene Dependency 1.0 2.58946 Cochlea TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.006 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null terminal loop COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.393162 binding GO Molecular Function Annotations 2015 1.0 null CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SFTPC_KO_GSE35989_48_mouse_lung (type II cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_265_OE_DPF3a_SRP322020 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.48046 sound GeneRIF Biological Term Annotations 1.0 null autosomal recessive nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.12909 MTMR14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24052 H2AFZ ENCODE Transcription Factor Targets 1.0 null 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.62535 Perturb_17786_KO_LDBI_SRP071739 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.44487 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.975876 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16819 Autosomal recessive nonsyndromic deafness 24 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_12729_KD_INCA1_SRP221667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.8514 Lateral cell cortex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.744 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26228 Perturb_7625_KD_ICE1_SRP120604 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_8079_KD_DDX21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.9521 neuro2a BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 CAL-51 COSMIC Cell Line Gene Mutation Profiles 1.0 null SACM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15189 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stereocilia ankle link complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.203 Perturb_7708_KD_Spt6_SRP132004 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.31377 Perturb_8228_KD_KIF1C_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.60088 MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.96743 ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.9041 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17616_OE_FOXP2_SRP225889 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_4592_KD_EBNA1_SRP064652 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44542 SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.92877 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB134VI CCLE Cell Line Gene Expression Profiles 1.0 1.45901 Stereocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 3.249 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.326 SERPINB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40202 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70319 Autosomal recessive nonsyndromic deafness 102 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.27117 single-organism process GO Biological Process Annotations 2015 1.0 null Bony labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.554 MAZ ENCODE Transcription Factor Targets 1.0 null Perturb_7179_KO_TrEx_SRP163035 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.78374 Perturb_101_KD_LATS_SRP353750 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.2985 BL70 DepMap CRISPR Gene Dependency 1.0 2.98264 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null Perturb_6709_OE_HNRNPK_SRP309086 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.78842 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Synaptic ribbon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.347 Perturb_5614_KD_BAF53A_SRP278652 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.78755 detection of mechanical stimulus GO Biological Process Annotations 2023 1.0 null posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.60869 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.25498 MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null head tilt MGI Mouse Phenotype Associations 2023 1.0 null HCC1569 COSMIC Cell Line Gene Mutation Profiles 1.0 null SPO11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54987 IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_257_KD_KLF6_SRP150445 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.51498 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE148252_7_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.373 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.32542 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853941 OFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2925 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8184_KD_DHX30_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.2121 MAP1LC3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64058 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.370496 striatum_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.896097 EP300_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.733645 ESET-19884257-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.850898 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PANC0327 CCLE Cell Line Gene CNV Profiles 1.0 1.33107 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65142 striatum_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.88809 trigeminal BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.04823 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.474903 Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null wildtype GeneRIF Biological Term Annotations 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841208 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_10352_KO_AATF_SRP257744 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.311 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06089 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.904198 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.9655 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22396 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.941273 cochlear hair cell degeneration MGI Mouse Phenotype Associations 2023 1.0 null apical plasma membrane GO Cellular Component Annotations 2015 1.0 null Perturb_1058_KO_ALPG_SRP277076 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.69859 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146982_3_v_6_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.791 ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3073 CDK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0784 Perturb_8801_KD_HOTAIR_SRP352837 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.89066 HT55 CCLE Cell Line Gene CNV Profiles -1.0 -1.52245 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.52288 Perturb_4375_KD_CREBBP_SRP072506 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.89318 FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4453 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-2355-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.998247 Perturb_12138_KD_OTX2_SRP347033 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.01392 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null REST_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebral infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.33651 Perturb_6291_KO_ZNF165_SRP390251 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.00688 revealed GeneRIF Biological Term Annotations 1.0 null Perturb_9828_KD_CRNKL1_SRP245546 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.5716 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7168_KD_ACTG1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.8079 HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.099932 GSE77178_1_v_3_ccnd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Autosomal dominant nonsyndromic deafness 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.276 Perturb_2533_KO_HSF1_SRP341615 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.3278 SAP30 ENCODE Transcription Factor Targets 1.0 null Perturb_3660_KO_ZCCHC4_SRP189763 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.73781 ZBTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50059 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06975 Perturb_9986_KD_U2AF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.22514 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH526 CCLE Cell Line Gene Expression Profiles 1.0 1.75576 Perturb_456_KD_SNHG17_SRP199046 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.0914 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.264148 Perturb_12533_KD_CK5_SRP342397 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0617 abnormal ear physiology MPO Gene-Phenotype Associations 1.0 null FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7239 endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.127476 Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.159 CDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78779 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55581 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3616-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HEB MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_8471_Mut_IDH1_SRP099826 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.76765 out GeneRIF Biological Term Annotations 1.0 null Perturb_10011_KD_AARS1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.57499 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.60661 Pendred Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.022 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058379 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28734 NOMO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.072103 actin-based cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.744 Perturb_12182_KD_PALB2_SRP015361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.39561 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21666 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057733 Perturb_14575_KD_H2AZ1_SRP314800 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 system process GO Biological Process Annotations 2015 1.0 null Perturb_10061_KD_CCAR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.54081 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.87177 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853941 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10352 SP4 ENCODE Transcription Factor Targets 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.92865 UACC812 CCLE Cell Line Gene Expression Profiles 1.0 1.86255 Autosomal dominant nonsyndromic deafness 51 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3462 TMEM88_KD_GSE43805_682_human_hES cells differentiated along the cardiac lineage GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_14586_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.5691 AFF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28176 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08077 OCIM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.54452 CREB1 ChEA Transcription Factor Targets 1.0 null basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36669 RERFGC1B CCLE Cell Line Gene Expression Profiles -1.0 -1.61351 Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.864385 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4564 Perturb_7801_KD_PAF1_SRP064356 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.81653 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.032022 Perturb_10095_KD_AGO2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.62681 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11883 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87033 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31331 Choanomastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.96 groin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.690451 Perturb_532_KD_TCF4_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.42276 apical plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 cos cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420385 Perturb_11414_KD_METTL3_SRP254897 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.12895 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.96847 PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-109-IPF1_PDX1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_4900_KD_NANOG_SRP158631 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.60221 Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 48 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.194 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31679 Congenital Deafness DisGeNET Gene-Disease Associations 1.0 null FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4499 Perturb_10005_KD_METAP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.46455 PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9720_KO_GCaMP_SRP067928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.0515 Perturb_8490_KD_CAG/CUG_SRP119324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_9649_KD_T208_SRP327946 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.5817 Perturb_7852_KD_XAB2_SRP193107 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.03891 Perturb_8188_KD_HNRNPC_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null five GeneRIF Biological Term Annotations 1.0 null REST_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.346 SW1783 CCLE Cell Line Gene Expression Profiles -1.0 -1.71646 rectum HPA Tissue Protein Expression Profiles 1.0 1.10979 YY1 ENCODE Transcription Factor Targets 1.0 null ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC1005 DepMap CRISPR Gene Dependency 1.0 2.65566 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083947 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE199874_3_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.683103 Perturb_14150_KO|KD_KBTBD4|RCOR1_SRP279638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null humans GeneRIF Biological Term Annotations 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15188 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.988061 Perturb_13960_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61665 Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GINS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50736 abnormal cochlea morphology MPO Gene-Phenotype Associations 1.0 null Chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.886 Autosomal dominant nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.801 Perturb_17617_KO_TIP60_SRP386872 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.97425 Perturb_10691_KD_IGF2BP1_SRP291708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.7579 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.45352 GSE158834_2_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null ZBTB7A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.01 Nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.125 Autosomal recessive nonsyndromic deafness 39 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 1B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.786 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7312_KO_CASC3_ERP118046 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.9561 Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ion transport GO Biological Process Annotations 2015 1.0 null Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.6261 Perturb_11691_OE_MYC_SRP253943 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.046 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Perturb_14175_OE_LONA_SRP267061 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.07129 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67589 plasma membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.00547 Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 79 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 Perturb_2617_KO_RB1_SRP252396 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.45701 orbital frontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38449 hsa-miR-890 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OV90 DepMap CRISPR Gene Dependency 1.0 2.77673 REST_Panc1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8367_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.52183 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11298 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.606 Cortical actin cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.713 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB436 CCLE Cell Line Gene Expression Profiles -1.0 -2.27666 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.57909 Perturb_493_KO_RN7SK_SRP367813 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 hsa-miR-3921 TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 normal GeneRIF Biological Term Annotations 1.0 null auditory receptor cell stereocilium organization GO Biological Process Annotations 2015 1.0 null hsa-miR-3591-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 ZNF629 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2938 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.49303 TCF3-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Neuroepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.793 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.65486 head tilt MPO Gene-Phenotype Associations 1.0 null DLD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1899 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Perturb_10003_KD_GPKOW_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.1986 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.931981 region GeneRIF Biological Term Annotations 1.0 null Autosomal dominant nonsyndromic deafness 2A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.048 impaired swimming MGI Mouse Phenotype Associations 2023 1.0 null Female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_8463_KO_IL10R2_ERP121014 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.54211 Autosomal recessive nonsyndromic deafness 67 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.654 HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -1.71652 USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1433 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8187_KD_HNRNPA1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.45673 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM2B-26808549-CHIP-SEQ-REH-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TM-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.195 Perturb_5660_KO_ID2_SRP336141 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.7462 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.06286 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_464_KD_IGF2BP1_SRP251876 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.339 SUDHL10 DepMap CRISPR Gene Dependency 1.0 3.0447 Amniotic cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.627 MAP3K11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04998 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-4770 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Perturb_17615_KI_FOXP2_SRP225889 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 MAPK1_knockdown_145_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.33296 Louping ill DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.177 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9589 abnormal cochlear inner hair cell morphology MPO Gene-Phenotype Associations 1.0 null thylakoid part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.059467 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89414 Perturb_9101_KD_MSX2_SRP304247 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.90793 Perturb_6420_KD_SPRY4IT1_SRP347515 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.54714 Perturb_12031_KD_EFEMP1_SRP213615 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.36662 Perturb_4904_KO_NSUN6_SRP233222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15463 Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7858_KD_FLNB_SRP216203 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.84349 VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_3845_KD_lncRNAAF339830_SRP161584 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.66104 macular holes DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.48999 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11338 Perturb_9822_KD_RUNX1_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.2375 Perturb_13681_KD_ATG5_ERP127841 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE158834_11_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Autosomal dominant auditory neuropathy 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Postsynaptic specialization membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.504 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15096_KD_RELA_SRP372154 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.21506 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.27 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056074 ZFP14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.5971 Perturb_7459_KD_ICE1_SRP120604 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044683 abnormal cochlear hair cell morphology MPO Gene-Phenotype Associations 1.0 null REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.830291 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046608 CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.954139 NFYA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79335 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.02732 Benign recurrent intrahepatic cholestasis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.039 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12187 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4678 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049907 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42847 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049832 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.977225 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05431 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 RAB2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48536 Perturb_5661_KO_ID2_SRP336141 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HHV8_72Hour-BEC_20080955_GSE16354 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.09248 methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25005 Perturb_8753_KD_ANLN_SRP083014 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 single-organism cellular process GO Biological Process Annotations 2015 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9106_KD_SNHG12_SRP223778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.74117 H4C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11882 stereocilium bundle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.751 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CL11 CCLE Cell Line Gene CNV Profiles -1.0 -2.14942 Perturb_365_KO_PTPN2_SRP108032 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.97054 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.067531 Perturb_8331_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.31224 Perturb_3620_KO_SMARCA4_SRP127343 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.05722 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4691-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 MESSA CCLE Cell Line Gene Expression Profiles -1.0 -2.48815 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.12563 orbital frontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79141 soundevoked GeneRIF Biological Term Annotations 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null Water vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.769 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1498 microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.135278 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4236 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67806 stomach HPA Tissue Protein Expression Profiles 1.0 1.10979 Perturb_7300_KO_SF3A1_SRP273617 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.21597 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09934 cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-374a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.898282 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07163 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 1.10979 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.889 REST_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14572_KO_EP300_SRP336466 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.89198 Perturb_8257_KD_RBM27_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.8794 Perturb_2386_Mut_ASXL2_SRP333775 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.45538 GSE158834_11_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_4746_KD_APOBEC3B/APOBEC3C/APOBEC3F_SRP050149 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.34138 Perturb_7648_KD_METTL3_SRP154311 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.36747 EIF3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55363 Perturb_10066_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.44067 Epidermodysplasia verruciformis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 vestibular labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.00807 MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9289_OE_KRAS_SRP172671 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.58295 Perturb_2496_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.75707 Perturb_6754_KD_UPF2_SRP327782 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.21924 Perturb_15574_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 AP-4 MotifMap Predicted Transcription Factor Targets 1.0 null H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.911925 BCLAF1_01_214 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.61284 GSE182680,GSE182683_7_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24885 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.194 Perturb_535_KD_KDM1a_SRP106818 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5537 EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AML193 DepMap CRISPR Gene Dependency 1.0 3.62217 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17029 REST_Panc1_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4559 UBTF ENCODE Transcription Factor Targets 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.04643 ETS1 ENCODE Transcription Factor Targets 1.0 null GSE217685_0_v_1_ddx20_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.843312 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891426 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.948008 POU5F1 ChEA Transcription Factor Targets 1.0 null GSE147056_4_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_7201_KD_DHX9_SRP080966 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.52392 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895535 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38137 Perturb_8185_KD_DNAJC2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.50234 Perturb_10002_KD_FTO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.23062 hsa-miR-4427 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Testicular cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.333 Perturb_13863_KD_TBX2/MYCN_ERP107244 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44853 Perturb_2521_KO_HSF1_SRP341615 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.78488 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.897249 Perturb_510_KO_RNASEL_SRP173964 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.61607 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8189_KD_HNRNPF_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Sexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.011 Neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.298 Microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.683 nonsyndromic GeneRIF Biological Term Annotations 1.0 null Perturb_12213_KD_EP300_SRP198455 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.98082 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6771 Perturb_2077_KD_PUM2_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.11161 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.347587 CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.310732 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25722 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4303 TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.665995 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.5693 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092527 hsa-miR-518d-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Perturb_14186_KD_GFI1_SRP289469 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.80599 GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.92923 Sensory processing of sound Reactome Pathways 2024 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14160_KD_IPO11_SRP316321 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.8936 FASTK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87168 BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_11523_KD_NR0B1_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.0637 Hearing loss ClinVar Gene-Phenotype Associations 2025 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8491_KD_CGA/UCG_SRP119324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.72676 Visceral mass TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 authors GeneRIF Biological Term Annotations 1.0 null hsa-miR-4302 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Lateral wall of outer hair cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.292 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1227 SIN3A_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.921043 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null ETS1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03339 RAD21 ENCODE Transcription Factor Targets 1.0 null Perturb_8919_KD_ARID1A/P300_SRP256204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.7357 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26228 neuron degeneration MPO Gene-Phenotype Associations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6003-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spleen-neutrophil Tabula Sapiens Gene-Cell Associations 1.0 1.4624 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29536 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14537_KO_NTNG1_SRP278999 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.78978 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11338 hsa-miR-4728-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Autosomal recessive nonsyndromic deafness 63 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.255 retinal pigment epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.620621 COLO201 CCLE Cell Line Gene CNV Profiles -1.0 -1.45361 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10272 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03128 pancreas GTEx Tissue Gene Expression Profiles 1.0 2.01272 Perturb_8091_KD_NOL12_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.63881 Perturb_12181_KD_BRCA1_SRP015361 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.64579 Perturb_7597_KO_TENT3A/TENT3B_SRP400572 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926751 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6104_OE_WSTF_SRP400122 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.97394 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47482 mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5387 Limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_8492_KD_Mir34a_SRP133851 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 hsa-miR-526a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 MCC26 DepMap CRISPR Gene Dependency 1.0 3.16378 abnormal hair cell morphology MPO Gene-Phenotype Associations 1.0 null EBC1 DepMap CRISPR Gene Dependency 1.0 2.01748 GSE151782_2_v_7_aim2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZDHHC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65251 Inner hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.619 Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETS1-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-520c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Perturb_7740_KO_Yap_SRP281854 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.50076 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01272 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17530_KO_TET1_SRP150212 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.98256 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Filament TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.844 mRNA_TCEA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_12370_OE_SNRPA1_SRP291347 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.86962 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null VDAC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99751 Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.4117 eyelid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.652183 SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3667 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.891021 DCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21021 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9911 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27913 RCC4 CCLE Cell Line Gene Expression Profiles -1.0 -2.32238 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8092_KD_PUF60_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.5194 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1814 abnormal sensory neuron morphology MPO Gene-Phenotype Associations 1.0 null Perturb_8018_KO_PXR_SRP257678 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 TP63_01_202 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.05585 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7714 PDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32245 Perturb_7663_KD_hnRNPC_SRP076733 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.95807 GSE239784_1_v_0_sat1_human RummaGEO Gene Perturbation Signatures 1.0 null Autosomal recessive nonsyndromic deafness 61 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 cell projection organization GO Biological Process Annotations 2015 1.0 null Perturb_14321_KD_CD95L_SRP111532 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Eosinophil percentage of white cells GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.839794 STAT3 ENCODE Transcription Factor Targets 1.0 null Perturb_7437_KO_YTHDF2_SRP082495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.71929 GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Salivary_Gland-duct epithelial cell Tabula Sapiens Gene-Cell Associations 1.0 1.62339 sporozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308974 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.894172 brain infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.300173 Sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.362 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.91115 Perturb_9661_KD_circTTN1_SRP260174 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_15384_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.98522 U178 CCLE Cell Line Gene Expression Profiles -1.0 -1.60444 KLRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53937 FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ChIP_REST_18959480 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_6642_KO_ZNF519_SRP371738 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.5543 molecular_function GO Molecular Function Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX3-22085726-MUSCLE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_7339_KO_TIP60_SRP386875 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.69933 EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_2781_KD_HECTD1_SRP109301 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.699 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66543 Perturb_13781_OE_IL10RB_SRP329434 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.2995 PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056043 SBC-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCT15 DepMap CRISPR Gene Dependency 1.0 4.04641 Perturb_8736_KD_SREBF1_SRP169608 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.06952 ZNF703 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18297 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.982016 REST_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_4_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-519c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42215 abnormal stationary movement MPO Gene-Phenotype Associations 1.0 null Perturb_7415_KD_HNRNPC_SRP040278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.41 mitochondrial inner membrane peptidase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.298826 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.972762 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420004 Perturb_2338_KD_MUC1C_SRP300048 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.73805 Eosinophil count GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.3301 MFAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1185 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26228 EVSAT DepMap CRISPR Gene Dependency 1.0 2.29224 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HCC33 CCLE Cell Line Gene Expression Profiles 1.0 2.18227 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.828402 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5123 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D1_1084_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052256 REST_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE146982_3_v_6_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null Autosomal recessive nonsyndromic deafness 74 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.637 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2935 CCLE Cell Line Gene CNV Profiles 1.0 1.55591 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.69097 TCF3 ChEA Transcription Factor Targets 1.0 null Gas bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.056 BXPC3 DepMap CRISPR Gene Dependency 1.0 2.47654 ARID3A ENCODE Transcription Factor Targets 1.0 null ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9372 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.02016 abducens nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32934 Immature fraction of reticulocytes GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.7 abnormal cochlear outer hair cell morphology MPO Gene-Phenotype Associations 1.0 null dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.98801 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44H-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PITX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5675 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.69422 Perturb_9096_KD_KDM2B_SRP128693 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.71445 PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_15430_KD_CDK7_SRP179971 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.165521 Saccule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.742 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Br_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16782 head tossing MGI Mouse Phenotype Associations 2023 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KP1N DepMap CRISPR Gene Dependency 1.0 2.04969 RECQL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43094 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3911 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 NCIH209 CCLE Cell Line Gene Expression Profiles 1.0 1.57024 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.035 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8232_KD_ZC3H8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.53481 REST_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13628_OE_Fosl2_SRP200662 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.41155 inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.934039 GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE241701_1_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_2720_KD_YAP1/WWTR1_SRP115100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.8049 cornea TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.425344 GSE217776,GSE217829_2_v_0_sgf29_human RummaGEO Gene Perturbation Signatures -1.0 null PSS131R DepMap CRISPR Gene Dependency 1.0 3.76423 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24805 CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.79888 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10199_KD_RUNX1/RUNX1T1_SRP291095 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.39882 stereocilium bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.476831 Usher syndrome type 1J DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.685 Perturb_16953_KO_MLX_SRP183152 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_9885_KD_HNRNPL_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.61689 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08817 Perturb_11388_KD_BRG1_SRP261084 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.19266 Autosomal recessive nonsyndromic deafness 21 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.817 establishment of localization GO Biological Process Annotations 2015 1.0 null GSE167546_1_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null Supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.893 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06051 GSE186647,GSE217287_1_v_3_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null BLTP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64573 Perturb_13013_KO_ALOX5_SRP367905 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.57394 cochlear outer hair cell degeneration MGI Mouse Phenotype Associations 2023 1.0 null Perturb_3668_KO_FASTKD_SRP277516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.0223 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.828402 Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OLIG2-26023283-AINV15-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cochlear hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.939 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.06448 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Vestibulocochlear nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.712 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17364 amygdaloid complex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21696 lhfp GeneRIF Biological Term Annotations 1.0 null hsa-miR-3938 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 TCF12/HEB-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_9372_KO_PRDM15_SRP288370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.64719 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72815 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.166777 Perturb_10000_KD_CPSF6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.2182 GSE198228,GSE198245_0_v_2_apoe_human RummaGEO Gene Perturbation Signatures -1.0 null SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.89829 organ of corti degeneration MPO Gene-Phenotype Associations 1.0 null Perturb_15097_KD_RELA_SRP372154 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.95437 KDM4A ENCODE Transcription Factor Targets 1.0 null intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.136192 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925928 Autosomal dominant nonsyndromic deafness 3B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.693 WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_2343_KD_KRT5_SRP342396 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.98146 Autosomal dominant nonsyndromic deafness 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.715 PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_17618_KO_TIP60_SRP386872 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.2845 Autosomal dominant nonsyndromic deafness 78 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 Perturb_7633_KD_ENL_SRP078067 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.67341 retinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.369628 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996041 Perturb_9010_KD_RELA_SRP061289 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.8594 intestinal obstruction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.420266 DES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26508 Mafb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.0647 Lateral part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.282 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_7731_KD_DIS3_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.12997 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.991948 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TFAP2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40952 ULK1_knockout_198_GSE60778 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.35843 EW22 DepMap CRISPR Gene Dependency 1.0 2.6716 Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.778212 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.856288 abnormal hearing physiology MPO Gene-Phenotype Associations 1.0 null Perturb_7738_KD_HRSP12/CNOT1_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.25394 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Parallel actin filament bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.635 Factor VII deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.224 Perturb_10001_KD_FMR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.56368 COLO792 CCLE Cell Line Gene CNV Profiles 1.0 1.47548 CA46 CCLE Cell Line Gene CNV Profiles -1.0 -3.07313 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null CAMA1 DepMap CRISPR Gene Dependency 1.0 3.7582 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 83 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.471 Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.099 hsa-miR-496 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.929613 Perturb_14288_KD_ALKBH5_SRP272155 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.80076 HK-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.563 Usher syndrome type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.192 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203485_1_v_0_sunitinib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2715_KO_TET1_SRP110516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.6199 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76506 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -2.20814 hsa-miR-635 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Peripheral vertigo DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.571 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21084 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890508 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4496 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Perturb_10078_KD_ZC3H8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.02275 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853422 Oligodendroglioma_CNS - Brain (MMHCC)_GSE2223 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.39888 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924786 Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34148 KE37 DepMap CRISPR Gene Dependency 1.0 2.29873 Perturb_8256_KD_RACK1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.23911 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049946 cochlear duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.937488 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8797 H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null response to abiotic stimulus GO Biological Process Annotations 2015 1.0 null Perturb_3957_Mut_GSDMB_SRP350967 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.5117 Vestibular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.605 SSC4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03629 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049228 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.13124 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40304 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Vestibular hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.705 Integrin alpha8-beta1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.013 PMC3470785-NIHMS377161-supplement-3.pdf-279-ZNF565_ZNF565 Rummagene Transcription Factor Associations 2026 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8195_KD_SMN1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.2512 abnormal hearing electrophysiology MPO Gene-Phenotype Associations 1.0 null Perturb_3627_KO_HDAC2_SRP355605 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.326 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.936899 Perturb_2557_KD_NXF1_SRP226431 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.26389 NCIH1915 CCLE Cell Line Gene CNV Profiles -1.0 -2.03299 RCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33745 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45459 SW948 CCLE Cell Line Gene Expression Profiles -1.0 -2.28838 cos-7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.546929 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08817 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87246 hsa-miR-1909 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 chr6_35835766_G_C_b38 GTEx eQTL 2025 1.0 1.42094 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8095_KD_SLBP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.6021 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10108_KD_EIF4A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.61967 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20845 hsa-miR-4653-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.361556 GSE166783_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null GATA3-21867929-TH1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13555 Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05545 hsa-miR-573 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 NZOV9 DepMap CRISPR Gene Dependency 1.0 2.47168 Stria vascularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.035 ONS76 DepMap CRISPR Gene Dependency 1.0 2.36678 Perturb_14177_KO_CD33_SRP387539 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_14627_KO_OGT_SRP146064 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 nonsyndromic deafness DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8333 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.865762 plasma membrane part GO Cellular Component Annotations 2015 1.0 null CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRECLH CCLE Cell Line Gene Expression Profiles -1.0 -1.70827 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null family GeneRIF Biological Term Annotations 1.0 null nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.66375 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.44763 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.39454 rough endoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.684644 cell part GO Cellular Component Annotations 2015 1.0 null inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.947701 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -2.06183 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1509 hearing/vestibular/ear phenotype MPO Gene-Phenotype Associations 1.0 null Perturb_2764_KD_FOXA1_SRP077334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.2885 RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8851_KD_MLKL_SRP165226 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.11194 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61004 MDAMB231 CCLE Cell Line Gene CNV Profiles 1.0 2.22464 DDX39B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04187 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04381 amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948064 H zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.863 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.696 FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3678-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Outer hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.751 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.856497 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.557043 Perturb_10044_KD_EFTUD2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.06313 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null establish GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.901938 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71591 Perturb_17650_KD_AFF4_SRP334520 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.67893 Perturb_8177_KD_RPS3A_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.48797 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04278 Perturb_15436_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_7527_KO_EED_SRP239128 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 outer SZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.905749 Autosomal dominant nonsyndromic deafness 48 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.398 rough endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.369684 Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3647-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Perturb_11940_KD_SMARCD1_ERP132006 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.32045 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_2148_OE_RKIP_SRP189735 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.20104 AMPA glutamate receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.434 spinal column TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.246124 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11702 cg12026tmhs GeneRIF Biological Term Annotations 1.0 null MM383 DepMap CRISPR Gene Dependency 1.0 2.41525 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stereocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.49418 GCT CCLE Cell Line Gene Expression Profiles -1.0 -1.46028 Perturb_397_KD_METTL3_SRP039397 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.86662 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.404026 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057646 Plantlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.922 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5484 Amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.8373 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62275 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.01327 ZBTB7A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null EN1 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-4756-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 affecting GeneRIF Biological Term Annotations 1.0 null hsa-miR-4650-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 NUDT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68926 GSE143692_0_v_1_trim8_human RummaGEO Gene Perturbation Signatures 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52409 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12076 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12509_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.54298 spinal cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0746 HNF4G JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4757 smooth muscle HPA Tissue Protein Expression Profiles 1.0 1.10979 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05604 TRRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18205 DCAF12L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05593 IRF2BPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09493 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15477_OE_MYC_SRP218384 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.93206 Ionotropic glutamate receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.454 Perturb_4916_KO_TFAP2A_SRP303667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.04716 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14086_KO_USP22_SRP199797 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.56028 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.847 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065379 multicellular organismal process GO Biological Process Annotations 2015 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.70441 Utricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.245 CENPJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62373 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_406_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.339 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null localization GO Biological Process Annotations 2015 1.0 null NCIH510 CCLE Cell Line Gene Expression Profiles 1.0 1.87976 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06482 Perturb_16494_KD_RBM39_SRP301121 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_9938_KD_DKC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.1549 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null brain cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.1185 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11842 Cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 2.01687 SHP77 CCLE Cell Line Gene Expression Profiles 1.0 1.68974 abnormal cranial ganglia morphology MPO Gene-Phenotype Associations 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24467 Apical complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.033 oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.341495 Perturb_9670_Mut_NR1H4_SRP115904 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.56197 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7718 Perturb_9815_KD_UTX_SRP062773 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.74442 Usher syndrome type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.225 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22933 EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.223361 abnormal membranous labyrinth morphology MPO Gene-Phenotype Associations 1.0 null Perturb_13496_KD_IGF2BP1_SRP252425 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-D1-D3_643_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 19139136-TableS3 GeneSigDB Published Gene Signatures 1.0 null amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07096 REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7163_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.6049 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0044 IGBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12967 abnormal cochlear sensory epithelium morphology MPO Gene-Phenotype Associations 1.0 null MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.935776 GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null Neurotransmitter receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.383 HCC1897 CCLE Cell Line Gene CNV Profiles -1.0 -1.59018 Perturb_9406_KD_GATA6AS_SRP279802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.37549 Perturb_2064_KD_BMAL1_SRP041298 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.42568 Perturb_15491_KO_BCOR_SRP168753 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.54696 PMC10806738-mmc2.xlsx-Table_S2-Table_S2_Table_of_significantly_adjusted_p-valued_0_05_down-regulated_genes_log2FC_-1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03621 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.24514 glial cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092552 Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 plasma membrane region GO Cellular Component Annotations 2015 1.0 null Perturb_326_KO_CDK12_SRP334730 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.9666 hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.914629 Perturb_6853_KO_PUM2_SRP273968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.73369 spiral organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.961175 hsa-miR-331-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33305 outer SZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836644 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26819 TCF3-18467660-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 30 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.377 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.39454 Perturb_8186_KD_DNAJC21_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.09963 flies GeneRIF Biological Term Annotations 1.0 null TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23317 Usher syndrome type 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.035 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.038 Perturb_11543_KD_DHX9_SRP175176 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.34659 Cochlear labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.115 REST_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.474903 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045221 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1475 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.16 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.877106 Perturb_8771_OE_MSX2_SRP304247 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.99312 photosystem COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.118139 Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9036 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40571 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.58852 Perturb_7230_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.34079 NCIH209 CCLE Cell Line Gene CNV Profiles 1.0 1.57191 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.066624 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11916 RBM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25116 Perturb_6622_KD_NFE2L2_SRP158498 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.69892 abnormal ear morphology MPO Gene-Phenotype Associations 1.0 null Perturb_15044_KD_PTBP1_SRP124244 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.2122 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PDCD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81318 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1961 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55581 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8730_KD_USP7_SRP256243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.56361 Hip circumference adjusted for BMI GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 sensory perception of sound GO Biological Process Annotations 2023 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1636 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.4238 HDAC2 ENCODE Transcription Factor Targets 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8190_KD_HNRNPU_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.98336 1321-n1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.848745 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 Perturb_17690_KD_MDMX_SRP393452 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.01442 SCRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31824 Perturb_18439_KD_G3BP1_SRP265843 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.77286 DMS114 CCLE Cell Line Gene CNV Profiles 1.0 1.57191 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_635_KO_SOX4_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.0317 Perturb_8922_KD_ARID1A_SRP192521 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.32708 REST_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null detection of stimulus GO Biological Process Annotations 2015 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.98031 abnormality of the inner ear HPO Gene-Disease Associations 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8928_KD_CHD4_SRP350011 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.12473 abnormal scala media morphology MPO Gene-Phenotype Associations 1.0 null Sensorineural Hearing Loss, Bilateral DisGeNET Gene-Disease Associations 1.0 null Unconventional myosin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.269 Exine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.914 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898613 Perturb_10097_KD_CNOT8_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.94614 Perturb_11350_KD_NFAT1_SRP173011 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01427 Sensory processing of sound by outer hair cells of the cochlea Reactome Pathways 2024 1.0 null Perturb_410_KO_IRE1_SRP353826 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.8239 GSE239844_6_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.92218 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36468 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.922 Cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.222 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.916202 F5 CCLE Cell Line Gene Expression Profiles -1.0 -1.67854 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2459_KD_GATA3_SRP268806 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.25613 urethra TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.472704 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_12730_KD_INCA1_SRP221667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.8695 Cochlear ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.09 arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.116471 CAOV4 DepMap CRISPR Gene Dependency 1.0 4.55551 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 astroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.125865 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 cochlear degeneration MPO Gene-Phenotype Associations 1.0 null GSE190384,GSE190386_0_v_8_fulvestrant_human RummaGEO Drug Perturbation Signatures -1.0 null SLIK (SAGA-like) complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.031 Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.55711 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8057_KD_IGF2BP3_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.7789 Perturb_7231_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.3404 endoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.502288 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3747 NCIH2126 DepMap CRISPR Gene Dependency 1.0 2.87222 detection of abiotic stimulus GO Biological Process Annotations 2015 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null F-actin capping protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.959 Perturb_14320_KD_CD95L_SRP111532 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_2373_KO_ASXL1_SRP305063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.7041 hsa-miR-3664-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 auditory system disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.918337 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.06937 Perturb_8917_KD_ARID1A_SRP256204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.78572 NFE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18977 NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null HS294T DepMap CRISPR Gene Dependency 1.0 3.89866 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_317_KD_TP63_SRP353945 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.89991 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8845 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null macroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.109869 hsa-miR-4646-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Perturb_12295_OE_PHGDH_SRP363494 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.4514 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 134.67 Perturb_7866_KO_SDE2_SRP239880 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.66489 Perturb_8399_KD_Srrm2_SRP195765 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.38372 f95 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.965 hsa-miR-711 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Perturb_14573_KO_EP300_SRP336466 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.54669 Perturb_7388_KO|KD_UPF3B|UPF3A_ERP130413 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 primary motor cortex (area M1, area 4)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.885038 dorsolateral prefrontal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61866 Hearing impairment ClinVar Gene-Phenotype Associations 2025 1.0 null SUM149PT DepMap CRISPR Gene Dependency 1.0 2.25527 hsa-miR-4768-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 Kinocilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.464 GSE146982_3_v_5_gpd1_human RummaGEO Gene Perturbation Signatures -1.0 null central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30167 embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.0426 HDAC1 ENCODE Transcription Factor Targets 1.0 null Perturb_3010_KD_PAX2_SRP119912 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.197 abnormal head movements MPO Gene-Phenotype Associations 1.0 null HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5158-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2598_KD_PRMT6_SRP131294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.52185 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29337 Perturb_1327_KD_COX2_SRP074235 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.64783 hsa-miR-320e TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 CAL29 DepMap CRISPR Gene Dependency 1.0 7.45982 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3139 REST_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7819 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.393374 Perturb_12338_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.59378 MAD2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72239 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.158005 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880381 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.95895 H3K9me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.994134 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TRIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47047 MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7639_KD_PCF11_SRP169609 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.91035 SKRC31 CCLE Cell Line Gene Expression Profiles -1.0 -1.50005 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926751 Perturb_8868_KD_PNN_SRP063860 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.94452 KIF1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64851 LN319 CCLE Cell Line Gene Expression Profiles -1.0 -1.76612 MYC ENCODE Transcription Factor Targets 1.0 null PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_8653_KD_DIAPH1_SRP399521 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.3866 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4852_KD_ZNF503_SRP059197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.7592 Autosomal dominant nonsyndromic deafness 3A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.694 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3626 recurrent viral infections GWASdb SNP-Phenotype Associations 1.0 0.643183 Perturb_5654_KD_FLI1_SRP117628 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.67123 hsa-miR-337-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Perturb_15995_KD_LUCAT1_SRP221619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.16639 tunisian GeneRIF Biological Term Annotations 1.0 null TUR COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2202 Perturb_8449_KD_LETN_SRP230777 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Stereocilia tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.602 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0366 Stereocilia tip link COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.617 EZH2 ENCODE Transcription Factor Targets 1.0 null COGN305 DepMap CRISPR Gene Dependency 1.0 2.35509 Perturb_7622_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.18042 Perturb_634_KO_HOXD3_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.88849 Perturb_8156_KD_FTO_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.51461 GSE88819_6_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04695 Stamen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.831 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.71602 hsa-miR-3185 TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 GSE236003_2_v_3_ubr5_human RummaGEO Gene Perturbation Signatures 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null FAM117B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42689 Perturb_8869_KD_PNN_SRP063860 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.8631 Perturb_6784_KD_ARID1A_ERP114370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.70738 RPMI-2650 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures -1.0 null autosomal GeneRIF Biological Term Annotations 1.0 null glial cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.180045 Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33972 Usher syndrome type 3A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.963 families GeneRIF Biological Term Annotations 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Auditory vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.402 stereocilium bundle tip GO Cellular Component Annotations 2015 1.0 null hsa-miR-575 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Perturb_9079_KD_HOXC6_SRP071155 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.23093 ZNF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01802 Perturb_3750_KD_NORAD_SRP149071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.62239 all GWASdb SNP-Phenotype Associations 1.0 0.031962 Sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.217 Imperforate anus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.46 SNU869 CCLE Cell Line Gene CNV Profiles -1.0 -1.52484 Perturb_13009_KO_ALOX5_SRP367905 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.58468 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37722 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.057412 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO205 CCLE Cell Line Gene CNV Profiles -1.0 -1.3574 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.845715 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59005 RCOR1 ENCODE Transcription Factor Targets 1.0 null abnormal somatic sensory system morphology MPO Gene-Phenotype Associations 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.085795 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03182 functional abnormality of the inner ear HPO Gene-Disease Associations 1.0 null hsa-miR-4266 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.061011 Perturb_9919_KD_MATR3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.37318 PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07424 Perturb_3573_KD_JAB1_SRP222371 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_554_KD_KDM5A_SRP277893 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 HS604T CCLE Cell Line Gene Expression Profiles 1.0 1.49538 prostate GTEx Tissue Gene Expression Profiles -1.0 -0.82869 GSE186660_2_v_1_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hair-cell stereocilium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.696 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null bidirectional circling MGI Mouse Phenotype Associations 2023 1.0 null Vestibular sensory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.678 overview GeneRIF Biological Term Annotations 1.0 null PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212761 Perturb_17627_KO_NF2_SRP153109 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.25068 Perturb_763_KD_SRRM2_SRP366559 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.27023 Perturb_12958_KO_KDSR_SRP308393 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.53775 GSE169205_0_v_7_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824976 GSE171572_5_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8346_KD_IGF2BP1_SRP252414 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.7579 MRPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15823 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3678 NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.0379 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Epithelial lining fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 Perturb_3712_KO_PIWIL1_SRP188921 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.16582 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.87872 GSE178532_2_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null Perturb_2730_KD_BCL11A/MBNL1_SRP258724 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.87447 Perturb_637_KO_SOX4_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.75331 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856329 Perturb_15447_KD_HDAC5_SRP273298 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.82224 Perturb_8751_KD_BRCA2_SRP125262 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.14139 REST_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 28 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.017 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09157 Perturb_8705_KD_SIRT1_SRP267968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.50062 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P2URK562 DepMap CRISPR Gene Dependency 1.0 2.23781 Perturb_15021_KD_RelA_SRP078053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Lung adenocarcinoma_LUAD_TCGA-69-7980-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2392_KD_TRIM28_SRP308699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.44647 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_2564_KD_GATA3_SRP188712 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.17395 abnormal sensory ganglion morphology MPO Gene-Phenotype Associations 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046009 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK4 ENCODE Transcription Factor Targets 1.0 null Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.117 Perturb_9816_KD_ARID5B_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15365 Perturb_11949_KD_NRF2_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.85623 UBB_KO_GDS3906_491_mouse_Testis - 7 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04985 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11469 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8078_KD_DAZAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.9642 Perturb_17612_OE_MYC_SRP301619 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.63202 Perturb_8461_KO_IL10R2_ERP121014 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.11923 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31139 cochlear inner hair cell degeneration MPO Gene-Phenotype Associations 1.0 null hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04137 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25661 plasma membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01103 Myosin XV complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.632 Perturb_8224_KD_DDX19B_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.70441 GSE103068_0_v_1_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null cellular component organization or biogenesis GO Biological Process Annotations 2015 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 Swim bladder TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.062 Perturb_7431_KO|KD_RBFOX2|RBFOX1_SRP068106 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.35791 RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9485 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.6239 Perturb_15146_KD_CUX1_SRP343012 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.01413 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TIMM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25926 Perturb_8264_KD_EEF2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.41128 FKBP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65219 astrocytoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.219707 Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07734 ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null RB1_KD_GSE50532_659_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hmgn1_KO_GDS5010_405_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11429_OE_WWTR1/FOSL1_SRP360169 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.65867 GSC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6878 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.832625 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.45708 HEPG2 CCLE Cell Line Gene Expression Profiles -1.0 -2.41721 abnormal outer hair cell stereociliary bundle morphology MGI Mouse Phenotype Associations 2023 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Inner ear vestibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.498 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.88086 Autosomal recessive nonsyndromic deafness 84A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.417 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null GSE218580_1_v_4_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null Perturb_13666_KD_AFAP1AS1_SRP253937 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.29827 Usher syndrome type 1C DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.52 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00863 brain cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.092135 Perturb_8495_KD_U2AF1_SRP221683 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.699 Perturb_8323_KD_INO80_SRP103083 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.52941 Vestibular labyrinth TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.969 Perturb_14375_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.7459 ZNF628 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34038 Perturb_9290_OE_KRAS_SRP172671 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.73264 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07577 Perturb_7160_KD_ACTG1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.9052 Perturb_3749_KD_NORAD_SRP149071 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.50199 Perturb_8926_KD_ZMYND8_SRP350008 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.86284 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053759 Perturb_3591_KO_DDX6_ERP024006 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.474 Perturb_8883_KD_CSL_SRP142324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.36165 posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.83454 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3806 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53432 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14373_KD_IGF2BP1_SRP150935 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -16.7459 OCIAML3 DepMap CRISPR Gene Dependency 1.0 2.84606 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE146982_7_v_5_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1734 bounding membrane of organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.070048 hsa-miR-4687-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 MAX ENCODE Transcription Factor Targets 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29086 USH2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.71 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heteroduplex GeneRIF Biological Term Annotations 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8929_KD_CHD4/ARID1A_SRP350011 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.75465 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12540438-Data_Sheet_1.PDF-20-ZNF527_ZNF527 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAPCA2B CCLE Cell Line Gene Expression Profiles -1.0 -1.99357 abnormal locomotor behavior MPO Gene-Phenotype Associations 1.0 null CORL311 CCLE Cell Line Gene Expression Profiles 1.0 2.04641 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03504 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null membrane region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.130239 REST-18959480-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Perturb_8132_KD_EIF4A3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3853 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.529208 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926751 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920324 horsetail-astral microtubule array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.568 Perturb_6434_KD_HOXA10AS_ERP131886 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.18906 GSE148252_5_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.96573 astrocytoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253908 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_14324_KD_EIF5A2_SRP294329 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.30582 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17620_KO_MLLT6_SRP245883 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8100_KD_ABCF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.62786 Perturb_9009_KD_RELA_SRP061289 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.90149 Perturb_8681_KD_ZNF827_SRP318474 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.48668 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.41618 Cervix - Endocervix GTEx Tissue Gene Expression Profiles 2023 1.0 1.76852 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.08232 SHF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39397 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891552 Perturb_93_KD_ANXA4_SRP127547 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.97832 Epibranchial TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.598 LK2 CCLE Cell Line Gene Expression Profiles -1.0 -2.93496 Sensory dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.86 CHST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22043 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3933 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.65006 TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null BLUE1 DepMap CRISPR Gene Dependency 1.0 3.2939 MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.75907 Perturb_3639_KO_BRD3_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.287 NB69 DepMap CRISPR Gene Dependency 1.0 3.49096 H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.50188 MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08061 PMC10290283-biol-2022-0622-sm3.pdf-278-ZBTB4_ZBTB4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null vitreous disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.60186 endoplasmic reticulum part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.403637 Modiolus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.122 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902831 REH DepMap CRISPR Gene Dependency 1.0 2.08734 heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.12294 Perturb_15572_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.73072 VIIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19829 Perturb_15423_KD_PXN_SRP199368 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.35831 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12946_KD_METTL3_SRP106608 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.86387 Y-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 Perturb_13691_KD_NSD2_SRP064418 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.34376 E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7872 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2516_KD_YAP1_SRP181909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.10135 VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949849 hsa-miR-3689f TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06706 head shaking MGI Mouse Phenotype Associations 2023 1.0 null Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.528 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.973514 temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879068 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null STK38L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00801 EGR1 ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.84954 urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067499 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.13394 hsa-miR-4676-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE92364_0_v_5_asparaginase_mouse RummaGEO Drug Perturbation Signatures 1.0 null Rootlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.145 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22397 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878821 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17302 inner ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.956859 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null sec61 translocon complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.681591 Superior semicircular canal dehiscence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.483 ZNF398 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13338 Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Outer ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.902 posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.976729 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null 9+2 non-motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.464 PRKD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09689 MCAS CCLE Cell Line Gene Expression Profiles 1.0 1.55243 present GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null nervous system disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853941 EP300 ENCODE Transcription Factor Targets 1.0 null Cortical cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.659 REST_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8497 NCI-H660 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.63 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 36 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.041 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6515 respiratory chain complex ii COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.442104 Perturb_3534_KD_KIF2C_SRP339333 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.56025 sensory perception of mechanical stimulus GO Biological Process Annotations 2023 1.0 null H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.52544 GSE110178_2_v_6_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Y-linked deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 Perturb_9107_KD_G6PD_SRP287480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.31494 Inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.342 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21249 Perturb_3515_KD_EIF4A3_ERP130710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.616 SIRT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93103 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2978_KD_NCOR1_SRP319239 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.17979 Perturb_9972_KD_BCLAF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.04851 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0623 GSE215351,GSE215794_7_v_0_kdm8_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null Perturb_9821_KD_MYB_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.09557 paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1608 SP4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endolymphatic hydrops DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.601 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.91989 Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterior medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25227 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7622 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2144 Perturb_1319_KO_IRF4_SRP201368 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.12862 GSE164529_0_v_3_tamoxifen_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_3841_KD_NFE2L2_ERP105460 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.5875 Perturb_10006_KD_SF3B1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.33523 IGR39 CCLE Cell Line Gene CNV Profiles -1.0 -1.38822 hsa-miR-1224-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 2.33872 GSE199204,GSE211619_4_v_3_glutamine_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_14761_KD_LATS1/LATS2_SRP345234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.79262 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01658 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Postsynaptic density membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.569 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.77959 Perturb_15476_OE_MYC_SRP218384 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.32405 Perturb_7745_KD_RRP6/DIS3_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.79851 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subiculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01963 cell part LOCATE Predicted Protein Localization Annotations 1.0 null abnormal motor capabilities/coordination/movement MPO Gene-Phenotype Associations 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.97626 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8280_KD_DDX5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.45083 GSE139948_3_v_6_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0832 Perturb_11427_OE_FOSL1_SRP360169 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.79194 GSE171177,GSE171181_1_v_2_e7107_human RummaGEO Drug Perturbation Signatures -1.0 null mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1263 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3689a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 recurrent infections GWASdb SNP-Phenotype Associations 1.0 0.300885 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.789 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WM115 CCLE Cell Line Gene CNV Profiles 1.0 1.38869 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.981207 GSE155695,GSE155696_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-7557-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 1.10979 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.922359 Ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 WTX_OE_GDS4802_34_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Lower tip-link density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.529 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.58108 Perturb_14904_KO_PRMT6_SRP125977 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.82701 Perturb_13959_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.73743 Perturb_9570_KD_CDH11_SRP318732 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.08829 Perturb_10107_KD_EIF2S1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.59466 Perturb_14151_KD_RCOR1_SRP279638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7169_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.74533 SIHA DepMap CRISPR Gene Dependency 1.0 2.14483 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.890508 SIN3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 LXR-22292898-THP-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE218580_1_v_3_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_2_KD_AGO2_ERP014062 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.9586 PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null GSE71468,GSE76476_2_v_1_rbfox1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE210667_3_v_2_rfx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 1.03496 MEC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.41351 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.71546 Benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Perturb_2667_KD_RBM39_SRP357624 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.07316 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15507_KD_MYC_SRP279303 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60693 HMGN3 ENCODE Transcription Factor Targets 1.0 null Bone_Marrow-nampt neutrophil Tabula Sapiens Gene-Cell Associations 1.0 0.728985 ZNF143 ENCODE Transcription Factor Targets 1.0 null AIMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04331 orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26046 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.529208 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8682 SMC1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15632 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4456 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 High light scatter reticulocyte percentage of red cells GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2699 CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8752_KD_ANLN_SRP083014 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.6877 Perturb_9288_OE_KRAS_SRP172671 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.71865 Perturb_8159_KD_MTPAP_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.16887 Endoplasmic reticulum cisternal network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.6 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7600_KO_LEF1_ERP109990 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_12308_KD_CDK12_SRP073459 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1424 nuclear outer membrane-endoplasmic reticulum membrane network COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.486904 avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypospadias DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.60303 ChIP_KLF4_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_15393_KD_CHKA_SRP050331 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.13651 Deafness, Autosomal Recessive 67 CTD Gene-Disease Associations 1.0 2.88009 Thyroid gland disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 SCLC21H CCLE Cell Line Gene CNV Profiles 1.0 1.45842 p93 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.617 Perturb_9395_OE_SOX9_SRP201900 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.69253 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.3611 apical part of cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_14760_KD_LATS1/LATS2_SRP345234 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.23519 Perturb_2526_KD_ZRANB2_SRP185438 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.52301 TEAD4_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.5755 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41026 REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_432_KD_RPAP3_DRP004966 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.96657 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8920_KD_P300_SRP256204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.53445 TAF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17311 KLF4-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Tectum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.202 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8089_KD_HNRNPA2B1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.78777 Perturb_3912_KD_Y14_SRP118481 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null Perturb_2318_KD_PRPF8_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.15913 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.81291 REST_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1350_KD_NSUN2_SRP212699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 nervous system disease GWASdb SNP-Disease Associations 1.0 0.05419 protein binding GO Molecular Function Annotations 2015 1.0 null Perturb_11576_KO_Zip8_SRP344283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.65245 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HSC1 DepMap CRISPR Gene Dependency 1.0 2.66006 PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1 Rummagene Transcription Factor Associations 2026 1.0 null glia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082732 Perturb_7777_KD_LINC000899_ERP112231 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.6431 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.35738 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_7803_KD_WDR61_SRP064356 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.65017 DNASE1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94496 Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fra-1_KO_GDS5078_402_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_7502_KD_PHF12_SRP194754 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3324 Perturb_9063_KD_NANOG_SRP100928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.967262 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Hearing Impairment DisGeNET Gene-Phenotype Associations 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.05543 Perturb_13495_KD_IGF2BP1_SRP291710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174751_0_v_1_postn_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE220520_6_v_0_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825193 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.89678 NFYC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39744 Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_7248_KO_LEF1_ERP109990 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_8803_KD_HOTAIR_SRP352837 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.46399 GSE193993_4_v_3_sstr2_human RummaGEO Gene Perturbation Signatures -1.0 null SF767 CCLE Cell Line Gene Expression Profiles -1.0 -2.11048 Perturb_8494_KD_U2AF1_SRP221683 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.0242 Perturb_11403_KD_CPT1A_SRP076884 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.40158 biological_process GO Biological Process Annotations 2015 1.0 null SARS-BatSRBD_Day2_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.79701 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.973006 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prdm4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.0127 Perturb_7164_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.92447 Lateral dorsal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.635 screening GeneRIF Biological Term Annotations 1.0 null Perturb_9852_KD_LUC7L_ERP124746 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.4849 Perturb_15023_KD_RelA_SRP078053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_3766_KD_lincDUSP_SRP111736 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.2366 Stereocilium bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 3.229 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01449 GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.891363 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 detection of mechanical stimulus GO Biological Process Annotations 2015 1.0 null Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.831952 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06465 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.89556 SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -1.81783 Perturb_3720_KD_CHD4/DNMT1_SRP049370 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.10029 eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP2 ENCODE Transcription Factor Targets 1.0 null ChIP_TCF3_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12291_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.26796 Perturb_13706_KD_SMARCA2_SRP247495 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.83528 PRKCI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70618 detection of stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 hsa-miR-4764-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 KP2 DepMap CRISPR Gene Dependency 1.0 2.31013 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2639 Perturb_3887_KD_EIF2B5_SRP124930 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.7878 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.849255 ELF1 ENCODE Transcription Factor Targets 1.0 null Deafness, autosomal recessive 67 ClinVar Gene-Phenotype Associations 1.0 null small cochlear ganglion MPO Gene-Phenotype Associations 1.0 null HCC1428 CCLE Cell Line Gene Expression Profiles 1.0 1.39071 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3713_KO_PIWIL1_SRP188921 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.82567 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4036 Perturb_11524_KD_NRF2_SRP092641 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853941 GSE121198,GSE129782_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8056_KD_IGF2BP1_SRP094100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.4597 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.850422 Perturb_15431_KD_MED1_SRP179971 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.911869 MDA-MB-415 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_17628_KO_PTPN14_SRP153109 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.54304 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.0 GSE164529_0_v_1_tamoxifen_human RummaGEO Drug Perturbation Signatures 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.913541 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8870_KD_PNN_SRP063860 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.96851 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1505 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04489 eGFP-HDAC8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3516_KD_MAGOH/MAGOHB_ERP130710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.9586 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.98931 QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 CORL24 CCLE Cell Line Gene Expression Profiles 1.0 3.40795 Perturb_14391_KD_PAX8_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.568025 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.663962 Vestibular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.665 GSE182680,GSE182683_7_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.29083 mania GWASdb SNP-Phenotype Associations 1.0 0.474903 DD-43-WW40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.219152 response to stimulus GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H4K20me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormal somatic nervous system morphology MPO Gene-Phenotype Associations 1.0 null Perturb_8450_KD_NPM1_SRP230777 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.46315 Perturb_8098_KD_TUFM_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.17832 detection of mechanical stimulus involved in sensory perception GO Biological Process Annotations 2025 1.0 null central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.942245 Trigeminal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.251 circling MGI Mouse Phenotype Associations 2023 1.0 null Perturb_13939_KO_USP29_SRP329795 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 sensory perception of sound GO Biological Process Annotations 2025 1.0 null Perturb_452_OE_MYC_SRP171977 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7178 GSE158834_10_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67415 ADAM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68283 Perturb_3798_KD_ZNF281_SRP377192 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.93719 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2791_KD_NEK9_SRP201903 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.0158 DB DepMap CRISPR Gene Dependency 1.0 3.8258 Perturb_2797_KD_RORC_SRP066204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.898224 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4795-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 ZNF496 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18543 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cSARS Bat SRBD_36Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63364 Perturb_1048_KD_H19_SRP132802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.765 Perturb_14328_KD_GRHL2_SRP157074 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Autosomal recessive nonsyndromic deafness 18B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.366 EPLC272H CCLE Cell Line Gene Expression Profiles 1.0 1.53542 icSARS-Cov_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.8794 ERA-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_3962_KO_PTPN2_SRP108032 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.38059 Perturb_14193_KO_PRMT5_SRP149386 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.41378 retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.260945 Perturb_9400_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.30794 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.846869 CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.677482 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.087615 PDZD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61163 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE181959_1_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null RAF1_activemutant_219_GSE42964 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.18409 HBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31188 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38816 Perturb_6141_OE_PPP1CA/PPP1R8_SRP118980 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.09021 cellular_component GO Cellular Component Annotations 2015 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871577 Autosomal recessive nonsyndromic deafness 97 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37124 astrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.127648 Perturb_12932_KD_DHODH_SRP340404 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.64684 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853941 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.43461 Perturb_6904_KD_OTX2_SRP347033 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_14374_KD_SRF_SRP150935 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.04047 Perturb_13723_KD_TP53_SRP162695 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.00386 Nr5a2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.4412 Sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.406 Perturb_3886_KD_CTR_SRP124930 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.2218 Perturb_11540_KD_EHMT2_SRP141734 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.98416 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8096_KD_SRSF5_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HNF4A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.6158 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26968 depression GWASdb SNP-Phenotype Associations 1.0 0.356941 chaperonin-containing T-complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.731 Perturb_531_KD_NKX22_SRP234742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.7946 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 16 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.346 Perturb_2986_KO_BAP1_SRP108473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_12166_KO_TRAM2_SRP254106 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.71211 COLGALT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04514 YD8 CCLE Cell Line Gene CNV Profiles -1.0 -1.44007 Perturb_7732_KD_RRP6_SRP062389 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.26723 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.870786 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2395_KD_TRIM28_SRP308699 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_9402_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.7808 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_14901_KO_H15_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.13616 Pollen wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.878 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_3903_KD_HNF4A_SRP123224 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.99484 sub-surface cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.613 Meniere's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.553 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_8759_KO_SETDB1_SRP141213 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.3077 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.927499 Perturb_13958_KO_YAP1_SRP194022 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.7693 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04479 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17029 REST_01_145 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.89407 Perturb_12905_KD_MDC1_SRP313175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.70649 REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1385 CCLE Cell Line Gene Expression Profiles 1.0 1.91316 Perturb_8293_KD_SUPV3L1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.26587 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.79417 GSE224970,GSE224971_1_v_0_sap30_mouse RummaGEO Gene Perturbation Signatures -1.0 null RB1_KD_GSE50532_660_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_9333_KO_FAT1_SRP158424 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.58707 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OTX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6025 Perturb_8301_KD_ETF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.60507 hsa-miR-1205 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6897_KO_TP53/ZNF84_ERP125489 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.54937 Communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.086 GABPA ENCODE Transcription Factor Targets 1.0 null abnormal motor coordination/ balance MPO Gene-Phenotype Associations 1.0 null loss GeneRIF Biological Term Annotations 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.94047 Perturb_8706_KD_SIRT1_SRP267968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.59924 Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.02 Nonsyndromic Deafness DisGeNET Gene-Disease Associations 1.0 null GSE71468,GSE76476_0_v_3_rbfox1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_15109_KD_MPP8_SRP218207 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.80543 Temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NUDUL1 CCLE Cell Line Gene CNV Profiles -1.0 -2.06737 Perturb_14304_KD_HNRNPC_SRP230637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.5942 Perturb_7161_KD_CD81_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.65652 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null paclitaxel_homo sapiens_gpl570_gse19136 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null glioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.101497 TM-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.354 catalytic complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04383 mitochondrial membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065323 detection of mechanical stimulus involved in sensory perception GO Biological Process Annotations 2015 1.0 null Perturb_2803_KO_CDH1_SRP267080 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.92103 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.961576 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_NR2F2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.961533 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25402 ICAM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89788 GSE158834_10_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.824001 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 1.10979 Perturb_8194_KD_SAFB2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.93752 Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_7621_KD_UPF1LL_SRP295982 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.5624 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051645 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044491 reductions GeneRIF Biological Term Annotations 1.0 null Perturb_8097_KD_SUCLG1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -15.4311 GSE126345_9_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMEM184C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12393 Perturb_8197_KD_TRIM56_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.50705 Perturb_5394_KD_LIM1_SRP402415 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_3009_KD_HNF1alpha/HNF1beta_SRP067843 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.38434 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9061_KD_NANOG_SRP100928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.9615 hsa-miR-2116 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Perturb_7950_KO_BAZ1A_SRP100570 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.96517 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1361 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_13614_KD_Srrm4_SRP041656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8968 Eye degenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.372 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.788 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30923 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29747 H4K20me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AMER1_OE_GDS4802_549_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autosomal recessive nonsyndromic deafness 8 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.664 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18352 Perturb_7323_KO_DCP2_SRP070463 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.4039 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null Retinitis pigmentosa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.415 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null trophozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.393819 response to mechanical stimulus GO Biological Process Annotations 2015 1.0 null Perturb_2611_KD_DAXXi_SRP216473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.25974 hsa-miR-154 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Perturb_2356_KD_IRX6_SRP072302 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.24825 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH520 CCLE Cell Line Gene Expression Profiles -1.0 -1.80262 cochlea TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04885 Perturb_12296_KD_RORC_SRP066204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.990963 Perturb_2609_KD_CLIP1_SRP212229 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.65195 vitamin c_homo sapiens_gpl570_gse11919 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Perturb_3655_KO_MTHFD1_SRP120974 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_9094_KD_SMARCA4_SRP293297 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.35262 Autosomal recessive nonsyndromic deafness 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.739 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31331 vestibular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.0085 GSE114992,GSE114993_7_v_3_irf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_1345_KD_ARID1A_SRP336358 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Autosomal recessive nonsyndromic deafness 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.881 REST_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1436 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5735_KD_NAP1L3_SRP121475 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.43455 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.030273 Perturb_8276_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.83521 Perturb_7853_KD_CCNF_SRP212181 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.09064 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lipoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.086 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11443 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3248 PSMD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0748 Perturb_3177_KO_KDM1A2a_SRP348808 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.51354 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11384_KD_CIT_SRP173646 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.34727 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57332 FOXO1-25302145-T-LYMPHOCYTE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6721_KD_EHMT2_SRP043290 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.27606 abnormal cochlear labyrinth morphology MPO Gene-Phenotype Associations 1.0 null SIN3B ChEA Transcription Factor Targets 1.0 null RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.13207 HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.98506 dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.140662 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null pyramidal cells of rostral CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.860071 Perturb_14599_KD_IGF2BP1_SRP252427 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.9078 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null stereocilium bundle tip COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_2717_KO_TET1_SRP110516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 KDM1A_KD_GDS5055_457_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.072537 TPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02862 sensory perception of mechanical stimulus GO Biological Process Annotations 2025 1.0 null paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03003 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.99116 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null significant GeneRIF Biological Term Annotations 1.0 null Perturb_9907_KD_EIF2S2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.8861 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12172_KO_CBFB_SRP159005 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.94194 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05747 deafness MPO Gene-Phenotype Associations 1.0 null SIN3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHP134 DepMap CRISPR Gene Dependency 1.0 3.21953 EKVX COSMIC Cell Line Gene Mutation Profiles 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29291 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11997 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253248 Neuromast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.729 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness 70 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.422 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.935089 NCIH841 DepMap CRISPR Gene Dependency 1.0 5.51709 hsa-miR-143 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null UMUC16 DepMap CRISPR Gene Dependency 1.0 3.38062 Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214017 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33673 Sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.696 PRADC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42524 EM2 CCLE Cell Line Gene CNV Profiles 1.0 2.01386 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null single-organism transport GO Biological Process Annotations 2015 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.14856 REST_Panc1_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5136 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.00172 iPS-18 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.34054 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2666_KD_JUN_SRP357624 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.03537 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null Perturb_6619_KO_NEUROD1_SRP388830 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.20415 peritonitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.274021 Perturb_7331_KD_PCIF1_SRP162223 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11877 Perturb_8886_OE_FOXM1_ERP109084 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.57145 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK3-25401928-HUVEC-HUMAN ChEA Transcription Factor Targets 2022 1.0 null occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91164 Perturb_7333_KO_SF3A1_SRP273617 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31155 displayed GeneRIF Biological Term Annotations 1.0 null RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.3883 Perturb_3253_KD_RPS19_SRP092068 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.94622 REST_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Blindness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.441 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null transport GO Biological Process Annotations 2015 1.0 null Perturb_2515_KD_TEAD4_SRP181909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MYBL2 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null epididymis HPA Tissue Protein Expression Profiles 1.0 1.10979 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.68934 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36623 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null glial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083542 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE124048,GSE124067_1_v_0_irf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Perturb_1_KD_AGO2_ERP014062 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 abnormal voluntary movement MPO Gene-Phenotype Associations 1.0 null H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null GSE183271_4_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42705 cv-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.200656 Perturb_10153_KO_ARID4B_SRP255645 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.00686 Cluster of actin-based cell projections COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.844 EOMES_OE_GDS5077_65_human_RUES2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KIF18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15214 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.917552 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.63085 Perturb_8050_KD_METTl14_SRP167173 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.69645 Perturb_7298_KD_PCIF1_SRP162223 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.0589 ANKRD35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11934 Perturb_12337_KD_TFEB_SRP226507 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.99514 P32-ISH COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal outer hair cell stereociliary bundle morphology MPO Gene-Phenotype Associations 1.0 null Perturb_6487_OE_MDM2_SRP302203 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.68558 HCC4006 CCLE Cell Line Gene CNV Profiles -1.0 -1.57041 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7183 Perturb_296_OE_ERG/MYC_SRP069177 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.35931 Perturb_9941_KD_MBNL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.28006 Phycobiont TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.843 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.911925 APP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02624 Autosomal recessive nonsyndromic deafness 12 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.106 CEP192 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00519 Perturb_9968_KD_UPF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05503 TUHR14TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.39588 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58178 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null hearing abnormality HPO Gene-Disease Associations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6684_KD_SMARCA2_SRP378606 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.901492 REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 2.09465 PMC11799275-Table1.docx-5-GLI1_GLI1 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2051_KD_EIF4A3_SRP271455 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.43399 mood disorder GWASdb SNP-Disease Associations 1.0 0.287917 hsa-miR-4642 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Perturb_2586_KD_RORC_SRP066204 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.6909 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null TOE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03565 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null schizoaffective disorder GWASdb SNP-Disease Associations 1.0 0.557043 MSTO211H DepMap CRISPR Gene Dependency 1.0 2.10825 Semicircular canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.952 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5841 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2721_KD_YAP1/WWTR1_SRP115100 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14888 Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.51332 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.39444 Auditory system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 RASA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05645 GGNBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.178 GSE77108_4_v_7_saha_human RummaGEO Drug Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04463 FOXO1_KO_GSE46025_480_mouse_CD8 T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Perturb_9908_KD_GRSF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.64989 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LC-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4029819-pone.0098069.s006.xlsx-Sheet1-Table_S5_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_metastases_p-value_0_01_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8087_KD_EIF4G2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.44572 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Autosomal recessive nonsyndromic deafness 86 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.24 CASKI DepMap CRISPR Gene Dependency 1.0 3.086 organ of Corti degeneration MGI Mouse Phenotype Associations 2023 1.0 null Perturb_72_KD_DNTM3B_SRP315598 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.58326 GSE148252_5_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH2106 CCLE Cell Line Gene Expression Profiles 1.0 2.19996 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.667215 Hypothyroidism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_9999_KD_BOP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.78497 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18526 LCAM1 DepMap CRISPR Gene Dependency 1.0 4.86804 HEP_3B2_1-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_7498_KO_USP10_SRP192777 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.86112 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6763 abnormal nervous system morphology MPO Gene-Phenotype Associations 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 IM9 DepMap CRISPR Gene Dependency 1.0 2.81573 FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_9370_KD_ARID1A89_SRP385862 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.75576 Perturb_8209_KD_RPS10_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.55799 GSE179036_1_v_0_trim24_mouse RummaGEO Gene Perturbation Signatures -1.0 null microsatellites GeneRIF Biological Term Annotations 1.0 null 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.13324 Stereocilia coupling link COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.612 Perturb_12570_KD_MSI1_SRP185353 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.68579 UNC13B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36643 Perturb_10225_KD_TopBP1_SRP167322 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.82963 Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Perturb_9942_KD_NAA15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.82605 translocon complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.827712 Perturb_1358_KD_GANAB_SRP299805 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.7844 Perturb_15404_KD_NRP2_SRP377764 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 496100352_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.02926 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_7963_OE_DKC1_SRP103222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.92385 Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 BNIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29539 FIGNL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02018 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.939863 Perturb_12379_KO_SMARCA4_SRP324802 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.88298 GSE146982_3_v_5_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926751 anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845442 vitreous detachment DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2356 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871577 Perturb_2560_KO_HSF1_SRP288220 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.83127 X-linked deafness 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.46 GSE156115_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.914751 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Leydig cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.186 Stereocilia ankle link COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.203 Perturb_9401_KD_MYCN_SRP104120 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.44557 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8713 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.927469 GSE217776,GSE217829_1_v_6_sgf29_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_1081_KO_BACH1_SRP174544 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.39485 dna GeneRIF Biological Term Annotations 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.432646 Perturb_18482_KD_DNMT1_SRP261597 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.65663 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.87774 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11306 GSE101239_5_v_1_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the middle ear HPO Gene-Disease Associations 1.0 null TCF7 ChEA Transcription Factor Targets 1.0 null Perturb_6103_OE_WSTF_SRP400122 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.2873 anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38062 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MAPK14_knockdown_139_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.20384 oxidoreductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.075123 abnormal auditory brainstem response MPO Gene-Phenotype Associations 1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.867162 Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7832_KD_NUDT21_SRP115462 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.24295 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.26661 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979877 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-7332-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null phenotypic abnormality HPO Gene-Disease Associations 1.0 null deafness MGI Mouse Phenotype Associations 2023 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048249 Perturb_8766_KD_H19_SRP073245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null recessive GeneRIF Biological Term Annotations 1.0 null prion disease GWASdb SNP-Disease Associations 1.0 0.744231 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.18998 increased or absent threshold for auditory brainstem response MPO Gene-Phenotype Associations 1.0 null Autosomal recessive nonsyndromic deafness 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.851 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87246 PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null inner ear receptor stereocilium organization GO Biological Process Annotations 2015 1.0 null DMS79 CCLE Cell Line Gene Expression Profiles 1.0 1.40948 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Apical part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.029 ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2054 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.4692 disease DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF Rummagene Transcription Factor Associations 2026 1.0 null NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 1.4633 nervous system phenotype MPO Gene-Phenotype Associations 1.0 null H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01854 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null inner membrane complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.73287 Perturb_7172_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.8677 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.4671 Perturb_15110_KD_PPHLN1_SRP218207 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.00507 Perturb_631_KO_SOX4_ERP117895 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.79289 response to external stimulus GO Biological Process Annotations 2015 1.0 null intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP1_01_208 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.61028 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7749 Perturb_11707_KD_NUDT21_SRP127253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.64523 REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203131_0_v_1_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null THBS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5099 increased or absent threshold for auditory brainstem response MGI Mouse Phenotype Associations 2023 1.0 null Goiter DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.347 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32373 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.943215 X-linked nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.43 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.86696 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05874 OC314 DepMap CRISPR Gene Dependency 1.0 4.8584 Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11702 Perturb_501_KD_TLR3/BRF1_SRP382324 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.7349 REEP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70405 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75422 Perturb_8729_KD_USP7_SRP256243 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.53445 mitochondrial part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.051591 NB7 DepMap CRISPR Gene Dependency 1.0 2.07932 Perturb_4905_KO_NSUN6_SRP233222 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.26304 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16439 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924786 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26228 abnormal cochlear hair cell stereociliary bundle morphology MPO Gene-Phenotype Associations 1.0 null Perturb_439_KD_MEP50_SRP073189 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.86496 Perturb_337_KD_MYC_SRP301562 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.09316 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-NR4A2-sequence_name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null ChIP_TCF3_18467660 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Ampulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 Perturb_9817_KD_E2A_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.6357 Head and Neck squamous cell carcinoma_HNSC_TCGA-HL-7533-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.624 ANAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37473 eye disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.274021 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30472 MS751 DepMap CRISPR Gene Dependency 1.0 2.68848 NCIH441 DepMap CRISPR Gene Dependency 1.0 2.11148 TXNL4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03721 KLF4 ChEA Transcription Factor Targets 1.0 null IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37937 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null detection of external stimulus GO Biological Process Annotations 2015 1.0 null abnormal cochlear ganglion morphology MPO Gene-Phenotype Associations 1.0 null hsa-miR-1231 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7771 RH30 CCLE Cell Line Gene Expression Profiles 1.0 1.37136 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58486 cerebral arterial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.436026 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Myosin III complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.207 Lipoma HMGIC fusion partner-like protein InterPro Predicted Protein Domain Annotations 1.0 null Perturb_8157_KD_GPKOW_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.851 REST_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_7165_KD_FTH1_SRP385887 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.38421 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Retinal degeneration DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.376 FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.261 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.849679 hearing impairment HPO Gene-Disease Associations 1.0 null Perturb_14068_KD_ALKBH5_SRP247667 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_10135_KD_RNPA1_SRP141197 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null circling MPO Gene-Phenotype Associations 1.0 null Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.057586 Perturb_12290_KO_ERO1_ERP137480 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96022 intracranial arteriosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.483224 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042535 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42847 Nervous system disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6831 Perturb_13752_KD_CREBBP_SRP233218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.70096 GSE142684_4_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8094_KD_PUM2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.22725 SUDHL10 CCLE Cell Line Gene Expression Profiles 1.0 1.78764 GSE220520_6_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.82582 EXOC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14421 ELK1 ENCODE Transcription Factor Targets 1.0 null Perturb_4257_KD_AR_SRP184695 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.53221 PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null REST_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.918034 SMAD4-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Usher syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.57 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.35592 Perturb_10075_KD_AQR_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.699 DMTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20623 YBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13097 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sensory processing of sound by inner hair cells of the cochlea Reactome Pathways 2024 1.0 null Usher syndrome type 2D DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.806 MOLP2 CCLE Cell Line Gene CNV Profiles 1.0 1.87709 Perturb_8196_KD_TIAL1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_8734_KD_SREBF1_SRP169608 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.74752 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.9365 body wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.148134 REST ChEA Transcription Factor Targets 1.0 null GSE171180,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 Cochlear duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.026 cochlear outer hair cell degeneration MPO Gene-Phenotype Associations 1.0 null outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.829737 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_18451_KD_H2AFJ_ERP124778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.82072 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8085_KD_DAZAP1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.95231 Spiral organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.037 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42705 outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.214714 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Polycystin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 CHLA57 DepMap CRISPR Gene Dependency 1.0 4.57041 deafness, autosomal recessive 67 OMIM Gene-Disease Associations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12987 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5393_KD_LIM1_SRP402415 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.75457 PMC11031166-SAG-2302-87_0_Appendix_1_SG_IHDS_(569_genes)_Final_List.xlsx-AP1-Genes_JUN Rummagene Transcription Factor Associations 2026 1.0 null STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.08215 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2877_Mut_KRAS_SRP404927 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.79894 GATA3-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Smooth endoplasmic reticulum cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.602 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Waardenburg syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.49603 Perturb_10096_KD_AGO3_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.97488 cellular component organization GO Biological Process Annotations 2015 1.0 null hsa-miR-570 TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.78947 REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.40178 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE217363_0_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3165 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Perturb_17619_KO_MLLT6_SRP245883 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890671 U937 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 SNU601 CCLE Cell Line Gene Expression Profiles 1.0 1.63745 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Disease DISEASES Curated Gene-Disease Association Evidence Scores 2025 1.0 4.0 hsa-miR-873 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Perturb_13866_KD_KDM6B_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.2501 GSE247084,GSE247087_0_v_1_cdyl_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.4683 neurodegeneration MPO Gene-Phenotype Associations 1.0 null IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal locomotor coordination MPO Gene-Phenotype Associations 1.0 null astroglia TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.124143 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.938142 Middle ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.514 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980728 Perturb_14903_KO_PRMT6_SRP125977 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.94103 Autosomal recessive nonsyndromic deafness 23 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.139 SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the ear HPO Gene-Disease Associations 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 3.14854 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Perturb_9185_OE_ZNF593AS_SRP298754 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.29602 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.958038 REST_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.892372 Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9944_KD_RBM15_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 14.7734 ZNF263 ENCODE Transcription Factor Targets 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE151829,GSE151831_3_v_0_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871577 Perturb_10030_KD_EIF4G2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.4565 Autosomal recessive nonsyndromic deafness 49 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.38 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.987898 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.854 transduction GeneRIF Biological Term Annotations 1.0 null H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_2327_KD_SF3B3_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.7771 hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27263 Orr TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.618 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cerebrovascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.182086 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04698 Perturb_8444_KD_IGF2BP1_SRP151057 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.48754 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Perturb_9820_KD_LMO1_SRP103740 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.98608 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.830474 disease of anatomical entity DISEASES Curated Gene-Disease Association Evidence Scores 1.0 null Perturb_11379_KD_OGT2_SRP311080 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.60025 REST_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST ENCODE Transcription Factor Targets 1.0 null unrelated GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null all HPO Gene-Disease Associations 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mouse GeneRIF Biological Term Annotations 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.995198 importance GeneRIF Biological Term Annotations 1.0 null NCIH2286 CCLE Cell Line Gene CNV Profiles -1.0 -1.46318 Sensory Perception Reactome Pathways 2024 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.3999 hsa-miR-374b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Perturb_13902_KO_AS3MT_SRP332674 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.87588 GSE183271_2_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null bilirubin metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.330295 GER cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.589 POLRMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10343 CCNT2 ENCODE Transcription Factor Targets 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18368 compared GeneRIF Biological Term Annotations 1.0 null head shaking MPO Gene-Phenotype Associations 1.0 null YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06806 hsa-miR-3689e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Perturb_15439_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 REST_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null detection of mechanical stimulus involved in sensory perception GO Biological Process Annotations 2023 1.0 null Perturb_8090_KD_HNRNPL_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.2434 Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_10105_KD_DDX3X_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.63438 Perturb_14896_KO_H13_ERP118037 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.10028 Perturb_15422_KD_PXN_SRP199368 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -14.6291 Perturb_14203_KD_ERBB2_ERP118856 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.18789 Perturb_7802_KD_RTF1_SRP064356 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.78863 small cochlear ganglion MGI Mouse Phenotype Associations 2023 1.0 null disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043558 E2F4 ENCODE Transcription Factor Targets 1.0 null Perturb_14615_KO_MTAP_SRP186070 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.35284 Sertoli cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.344 vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.21098 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41364 ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.032168 Perturb_15405_KD_NRP2_SRP377764 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 hsa-miR-4314 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5454 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12636 JUND ENCODE Transcription Factor Targets 1.0 null NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.45778 COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42847 GSE210662_2_v_0_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.832474 abnormal organ of corti morphology MPO Gene-Phenotype Associations 1.0 null FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2727 Perturb_10219_KO_TNFAIP6_ERP126958 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.6346 GSE223609,GSE223610_0_v_1_kdm6a_human RummaGEO Gene Perturbation Signatures 1.0 null MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3782 NCIH2196 CCLE Cell Line Gene Expression Profiles 1.0 1.73105 Perturb_314_KD_XBP1_SRP279319 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.42571 NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.7906 hsa-miR-548l TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 COR-L26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84383 Perturb_5548_KD_ASC_SRP310464 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.89586 Hypospadias DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.136 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null LB647-SCLC COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_2303_KD_BRCA2_SRP268983 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.77236 single-organism localization GO Biological Process Annotations 2015 1.0 null Perturb_6852_KO_PUM2_SRP273968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.25754 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periplasmic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.06195 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.887473 Auditory capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.639 GSE252857_1_v_3_klf15_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3203_KD_ARRB1_SRP302544 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.34811 behavior/neurological phenotype MPO Gene-Phenotype Associations 1.0 null GSE196117_1_v_8_clarithromycin_human RummaGEO Drug Perturbation Signatures 1.0 null VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19881 detection of mechanical stimulus involved in sensory perception of sound GO Biological Process Annotations 2015 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17391 hsa-miR-519b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0945 CPCN CCLE Cell Line Gene Expression Profiles 1.0 2.64112 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61571 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_3252_KD_RPL5_SRP092068 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.95105 Perturb_7576_KD_ZC3H4_SRP343726 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.7306 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.842383 Perturb_8154_KD_CPSF6_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.3045 Perturb_14154_KD_RCOR1_SRP279638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -13.9387 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.951312 hearing GeneRIF Biological Term Annotations 1.0 null hsa-miR-3605-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE157777_2_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures -1.0 null REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2374_KO_ASXL1_SRP305063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.93913 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12925 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2157 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cholinergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.633 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5259 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.815743 Scolopale cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.543 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29035 HUH1 CCLE Cell Line Gene Expression Profiles 1.0 1.42216 Perturb_13779_OE_IL10RB_SRP329434 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Autosomal recessive nonsyndromic deafness 77 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.968 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null impaired hearing MPO Gene-Phenotype Associations 1.0 null Leber congenital amaurosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.083 vascular dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.483224 kidney cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.087106 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982878 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.827593 RUNDC3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05275 Perturb_8112_KD_SUPT6H_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.60612 REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal inner ear morphology MPO Gene-Phenotype Associations 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.80048 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 2.59998 FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Johnston's organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.549 Perturb_9841_KD_KDM6A_SRP254623 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.42772 Perturb_14955_OE_PRDM1_SRP287780 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.45935 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1255 Perturb_5391_KD_DEANR1_SRP019241 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.64503 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09387 GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null autosomal recessive inheritance HPO Gene-Disease Associations 1.0 null Autosomal recessive nonsyndromic deafness 22 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.196 brain disease GWASdb SNP-Disease Associations 1.0 0.163651 Labyrinthine zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.846 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Moh TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.836 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null H9 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_8131_KD_EIF2S1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.60942 bone BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.901808 Perturb_4011_KD_SMAD3_SRP149729 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.81104 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mammalian phenotype MPO Gene-Phenotype Associations 1.0 null GSE139966_4_v_3_figla_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_2478_OE_YAP_SRP254362 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.686 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.104878 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.82582 Perturb_13859_KD_MYCN_ERP107244 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.01049 fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076949 diaphanousforked GeneRIF Biological Term Annotations 1.0 null Perturb_2976_KD_ZFX_SRP115395 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.24219 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7736_KD_CNOT1_SRP155278 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.3341 Perturb_2794_KD_PSMD2_SRP173284 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.65936 Usher syndrome type 1G DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.641 KAT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2518 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70767 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.35193 Perturb_8125_KD_LARP4_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.58649 abnormal cochlear inner hair cell morphology MGI Mouse Phenotype Associations 2023 1.0 null Space motion sickness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 PMC9811745-40246_2022_449_MOESM1_ESM.xls-Sheet1-HOXA2_HOXA2 Rummagene Transcription Factor Associations 2026 1.0 null RCOR1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perilymphatic space TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.254 H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6833_KD_CASC9_SRP182039 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.70156 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057537 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57963 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.9764 Perturb_9785_KD_EPS15_SRP339484 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.07813 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null L1CAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16503 auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.24341 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11338 Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Grey cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.732 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.05754 Hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 3.037 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.93281 NANOG ChEA Transcription Factor Targets 1.0 null chr6_35784118_G_A_b38 GTEx eQTL 2025 1.0 1.37304 amplitude GeneRIF Biological Term Annotations 1.0 null GSE157894_1_v_3_cystine_human RummaGEO Drug Perturbation Signatures 1.0 null Ribbon synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.032 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.3539 Perturb_12927_KO_CLPB_SRP181053 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.37553 M059K CCLE Cell Line Gene CNV Profiles 1.0 1.52954 Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28034 Perturb_7833_KD_CPSF6_SRP115462 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.11756 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31499 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16439 Perturb_10165_KD_DOT1L_SRP292382 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -11.6515 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18609 dorsolateral prefrontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.851233 GSE158834_10_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_6274_KD_HOXCAS3_SRP158772 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.26387 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26087 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE103068_5_v_1_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null ear TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.847904 OVSAHO CCLE Cell Line Gene Expression Profiles -1.0 -1.59102 Perturb_10109_KD_EIF4B_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.76788 Perturb_15385_KD_FGF13_SRP319157 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.35186 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.77726 CREB1 ENCODE Transcription Factor Targets 1.0 null EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_1992_OE_IRX5_SRP357294 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.3979 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1354_OE_U11_SRP314103 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.9137 NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.7228 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.926751 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4459 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Perturb_12268_KO_CECR1_SRP255026 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.35601 Perturb_2075_KD_PUM1_SRP072710 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.52335 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90239 Perturb_14178_KO_CD33/CD123_SRP387539 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LD-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globe disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.273664 Perturb_12341_KD_METTL18_SRP235648 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_15441_KD_TMPOAS1_SRP273203 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MIS18BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08338 bidirectional circling MPO Gene-Phenotype Associations 1.0 null GSE108675_3_v_0_slc1a4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE252857_1_v_3_prednisone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Perturb_7557_Mut_ASXL1_SRP305063 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.94509 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04805 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7699 NCIH1436 CCLE Cell Line Gene Expression Profiles 1.0 2.41371 Hypolemmal cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.606 ZNF417 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6016 PMC6813882-NIHMS1526297-supplement-2.pdf-18-KLF6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null CUEDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08498 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.842799 E2F6 ENCODE Transcription Factor Targets 1.0 null EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0606 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.76689 MAZ_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_10_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_14574_KO_EP300_SRP336466 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.57294 NCIH522 DepMap CRISPR Gene Dependency 1.0 2.14319 H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.26043 NCI-H522 COSMIC Cell Line Gene CNV Profiles 1.0 2.93899 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.876574 RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.0869 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57804 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.888991 CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Autosomal dominant nonsyndromic deafness 33 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.58 intracranial arterial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.436026 Perturb_13653_KD_CELSR2_SRP149837 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.65542 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051918 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.168 membrane region GO Cellular Component Annotations 2015 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.50396 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null succinate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.482467 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871577 Autosomal dominant nonsyndromic deafness 36 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.093 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03172 potentials GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.59216 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive nonsyndromic deafness DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 3.092 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.6141 Perturb_504_KD_METTL3_SRP039397 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.91173 RIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74835 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.58852 MAFK ENCODE Transcription Factor Targets 1.0 null telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null impaired balance MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.65722 Perturb_13867_KD_KDM6B_SRP258989 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.35457 stereotypic behavior MPO Gene-Phenotype Associations 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20002 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE166783_3_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11971_KO_SUZ12_SRP327198 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.09064 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21653 Perturb_8225_KD_DKC1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.78655 Autosomal dominant nonsyndromic deafness 27 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.578 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.7618