association	dataset	threshold value	standardized value
Perturb_4708_KD_Dnmt3b_SRP069225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.49319
Perturb_11207_KO_Zhx2_SRP332476	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30374
KCND3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620977
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
D458	DepMap CRISPR Gene Dependency	1.0	6.53545
HIPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050258
Perturb_3836_KO_ING3_SRP304782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.18517
NCIH1648	DepMap CRISPR Gene Dependency	1.0	3.25372
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14511_KD_TP63_ERP109983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Erythema	DisGeNET Gene-Disease Associations	1.0	null
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6306_KD_UBE2CP3_SRP299256	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.96305
JHH7	DepMap CRISPR Gene Dependency	1.0	3.77601
Perturb_7681_KD_UPF2_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.63885
Behcet Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Hepatitis C	DisGeNET Gene-Disease Associations	1.0	null
Psoriasis	DisGeNET Gene-Disease Associations	1.0	null
WNK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598302
Perturb_17178_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.2218
Perturb_2634_KO_PKM_SRP322205	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	3.18865
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
FOXM1-32153563-SKOV3-HUMAN-OVARY-OVARIANCANCER	ChEA Transcription Factor Targets 2022	1.0	null
SMARCA4-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15233_KO_Nm1_SRP212300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_17193_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PPAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046949
Perturb_6677_KD_ROBO3_ERP130576	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.301
Perturb_506_OE_GPD1_SRP252809	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_11735_Mut_KLF5_SRP091857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.60677
ENPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522957
BICR10	DepMap CRISPR Gene Dependency	1.0	2.52636
Perturb_2792_KO_LATS1/LATS2_SRP331116	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
OAZ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057022
NCIH1568	DepMap CRISPR Gene Dependency	1.0	2.37343
Perturb_6660_OE_Mir29a/Mir29b1_SRP220297	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.92659
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_18011_KO_miR17/miR20a/miR92a1_SRP050491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.49706
OR2L13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00503606
Unspecified Visual Loss	DisGeNET Gene-Phenotype Associations	1.0	null
SLC25A34	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00837326
WEE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00377986
Perturb_1397_KO_Psen1_SRP220423	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_17168_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Fleck Corneal Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UACC62	DepMap CRISPR Gene Dependency	1.0	4.41156
CD58	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463871
SNU601	DepMap CRISPR Gene Dependency	1.0	3.33826
PTK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00738686
Perturb_7807_KD_CSTF2_SRP071700	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.1876
negative regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
HUH6	DepMap CRISPR Gene Dependency	1.0	3.32295
KP363T	DepMap CRISPR Gene Dependency	1.0	4.13365
Perturb_9005_KD_GATA6_SRP014027	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.61582
NOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450144
HSD17B4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00502208
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
C99	DepMap CRISPR Gene Dependency	1.0	3.24904
PHKG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00571626
Perturb_11866_OE_Il13_ERP005901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3587
Childhood Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14562_KD_SULF2_SRP361678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKOV3	DepMap CRISPR Gene Dependency	1.0	2.20312
Perturb_15889_KO_Dnajb6_SRP357786	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.11116
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GHRHR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557791
THP1	DepMap CRISPR Gene Dependency	1.0	2.37905
SFTPC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00468151
Perturb_5036_KD_Smarcc1_SRP221174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43719
Perturb_6249_KO_Chrna7_SRP338769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SH4	DepMap CRISPR Gene Dependency	1.0	2.73372
JHH5	DepMap CRISPR Gene Dependency	1.0	2.45118
SKIC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00359881
OVTOKO	DepMap CRISPR Gene Dependency	1.0	3.13608
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CD99	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559503
Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17187_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_7132_OE_RNASEH1_SRP257541	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Leishmaniasis	DisGeNET Gene-Disease Associations	1.0	null
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2023	1.0	null
Craniofacial Asymmetry	DisGeNET Gene-Disease Associations	1.0	null
Perturb_8454_OE_MT1G_SRP352861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.00535
Gingivitis	DisGeNET Gene-Disease Associations	1.0	null
CTSW	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479094
Perturb_8009_KD|OE_PSAT1|TP53_SRP406950	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46956
SIRT6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678579
Amyloidosis	DisGeNET Gene-Disease Associations	1.0	null
Crohn Disease	DisGeNET Gene-Disease Associations	1.0	null
SEMA4C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00694631
Perturb_17293_KD_lncRNA5251_SRP239062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Tuberous Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
IFNA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00681281
Spinal Muscular Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Perturb_17197_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Periodontitis	DisGeNET Gene-Disease Associations	1.0	null
CHLA15	DepMap CRISPR Gene Dependency	1.0	5.0676
Perturb_17191_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Ectromelia	DisGeNET Gene-Disease Associations	1.0	null
Perturb_17176_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CD320	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552951
IGLON5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519896
Malaria	DisGeNET Gene-Disease Associations	1.0	null
Perturb_17166_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Familial Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
LEP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00711861
Perturb_10311_KO_Dkk3_SRP067265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76885
Perturb_10397_KD_LOXL2_SRP217697	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5474_KO_Tsc2_SRP227934	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.7014
Mental Retardation	DisGeNET Gene-Disease Associations	1.0	null
Perturb_14142_KD_MYC_SRP178198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.16584
EDNRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678885
Perturb_5604_KD_METTL1_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SKRC20	DepMap CRISPR Gene Dependency	1.0	5.46365
RSAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609344
CAL62	DepMap CRISPR Gene Dependency	1.0	3.69632
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GJB5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00496625
LRRC37A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00512979
KLK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605523
RAD51	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578463
Perturb_6297_KD_CGA_SRP355115	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.9483
Astrocytoma	DisGeNET Gene-Disease Associations	1.0	null
HPRT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385618
Perturb_5861_KD_H3f3a_SRP133189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0025
N4BP2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492209
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.36096
DPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558834
Perturb_17179_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_17195_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_1016_KO_Nt5e_SRP404924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4273
KHK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516064
Apnea	DisGeNET Gene-Phenotype Associations	1.0	null
PACADD161	DepMap CRISPR Gene Dependency	1.0	7.457
TNFRSF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520309
Perturb_17180_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
JHU029	DepMap CRISPR Gene Dependency	1.0	6.19547
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BICR78	DepMap CRISPR Gene Dependency	1.0	5.00737
Perturb_17185_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5624_KD_KLF5_SRP307776	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.67858
Perturb_17198_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ALDH4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526168
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JURLMK1	DepMap CRISPR Gene Dependency	1.0	2.36029
B4GALNT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520925
Perturb_17192_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14364_KD_SCD_SRP352005	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GIMAP8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621224
Perturb_4350_KO_Jag1_SRP045701	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
EPHA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557777
Perturb_10873_KO_Slc25a34_SRP342539	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.37998
Perturb_12695_OE_Hoxb13_SRP250504	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.6048
SNU738	DepMap CRISPR Gene Dependency	1.0	2.73049
RAPGEF6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00684339
VPS35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501925
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13429_KO_Usp28_SRP044274	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.46291
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.18933
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56724
FASTKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049407
SLC5A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00575586
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6720_KO_KDM3A_SRP128505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PLXNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669157
Perturb_1109_KO_Nkx2_SRP032537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1325
NPC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00453392
Perturb_473_OE_ARAF_SRP259289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.41262
Gestational Diabetes	DisGeNET Gene-Phenotype Associations	1.0	null
BPIFA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00480287
A172	DepMap CRISPR Gene Dependency	1.0	3.37465
DDR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603171
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
SLC38A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00682936
Perturb_4744_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.64112
Helicobacter Pylori (H. Pylori) Infection In Conditions Classified Elsewhere And Of Unspecified Site	DisGeNET Gene-Disease Associations	1.0	null
Perturb_17171_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_4351_OE_Sall1_SRP409197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.57397
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
SLC1A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00785447
TCF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577556
Systemic Scleroderma	DisGeNET Gene-Disease Associations	1.0	null
regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
Motor Neuron Disease	DisGeNET Gene-Disease Associations	1.0	null
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_434_KD_U2AF1_SRP055860	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.89787
GLUL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00783891
Ganglioglioma	DisGeNET Gene-Disease Associations	1.0	null
ATF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00248536
PIK3C2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0087425
Medulary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ADAM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608359
FDCSP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603309
Perturb_17175_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Smallpox	DisGeNET Gene-Disease Associations	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	2.98083
Giant Cell Arteritis	DisGeNET Gene-Disease Associations	1.0	null
Perturb_11959_OE_Snal1_SRP170547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.05201
Perturb_7049_KO_Notch1_SRP057171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.41945
Rubella	DisGeNET Gene-Disease Associations	1.0	null
Perturb_12033_KD_MIR241_ERP110145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_6943_KO_Xirp2_SRP259323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.90658
APEH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00610047
CYP3A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00526122
APCDD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585029
Perturb_13602_KD_AREG_SRP059835	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.699
BTBD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00576242
PRKAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00437316
Perturb_14351_KD_Notch2_SRP285379	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.3915
EOMES-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13210_KO_Mbd3_ERP001253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Pancreatic Ductal Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17169_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
C1QBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00689058
Perturb_9554_KO_Atg16l1_SRP159288	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.4312
LPS853	DepMap CRISPR Gene Dependency	1.0	2.16108
Perturb_14310_KD_CD83_SRP178846	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
BCL2L2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00323029
ZEB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0065802
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	3.07153
Perturb_13114_KO_Foxm1_SRP194062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_3837_KO_ING3_SRP304782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.78022
BE2M17	DepMap CRISPR Gene Dependency	1.0	4.75665
NDUFA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00387836
Perturb_8934_KO_EZH2_SRP250286	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
X-Linked Lissencephaly	DisGeNET Gene-Disease Associations	1.0	null
Newmann-Pick Disease	DisGeNET Gene-Disease Associations	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	5.22628
Perturb_13730_KD_MMR_SRP193477	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.539
Retinopathy Of Prematurity	DisGeNET Gene-Disease Associations	1.0	null
CPS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535601
Perturb_8675_KD_ZNF281_SRP251817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.4087
NTPCR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642139
Perturb_14510_KD_TP63_ERP109983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_17165_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_5789_KO_Tnfrsf11a_SRP103818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.7234
FHAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606032
Childhood Astrocytoma	DisGeNET Gene-Disease Associations	1.0	null
CKS1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587853
AATK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00748953
COX8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00452827
Perturb_14311_OE_CD83_SRP178846	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.19453
EOL1	DepMap CRISPR Gene Dependency	1.0	2.10975
Perturb_7884_KO_DDX39B_SRP278200	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MBNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00740772
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
BMI1-19503595-MEFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17170_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_17199_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.6287
GGPS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00462074
Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
RSBN1L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545885
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_14618_KO_SMAD4_SRP255626	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.88186
Perturb_16949_OE_GATA6/ZBED2_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.0835
KPNYS	DepMap CRISPR Gene Dependency	1.0	2.31333
Perturb_10230_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.78054
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	2.1455
DNMT3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00354343
PACSIN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054577
Glossitis, Benign Migratory	DisGeNET Gene-Disease Associations	1.0	null
CD40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00302297
Perturb_15814_KO_NRF2_SRP343083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.66917
Perturb_17182_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_13291_KO_Trp53/Cry1/Cry2_SRP149358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
FLI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00645199
T3M3	DepMap CRISPR Gene Dependency	1.0	4.27402
TNFRSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540229
RAD21	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0111673
SAMHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00452806
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.17223
MTAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472367
SLC1A7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0047694
Perturb_3041_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lyme Arthritis	DisGeNET Gene-Disease Associations	1.0	null
PLA1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00528894
KCNAB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00520504
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BLZF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00568367
MCMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618981
Perturb_16549_KO_Cdk8_SRP061642	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_15481_OE_ERG_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PRKD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00715149
TMEM229B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601122
CD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00419831
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
Perturb_15571_OE_circCSPP1_SRP286288	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.7075
786O	DepMap CRISPR Gene Dependency	1.0	2.05955
Perturb_15566_KD_YAP1_SRP333272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.658
Perturb_9555_KO_Atg16l1_SRP159288	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_15513_KD_WWTR1_SRP096943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.5732
Central Neuroblastoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13115_KO_Foxm1_SRP194062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.9769
Perturb_15703_KD_JMJD1A/AGE_SRP353924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DPYD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542142
GSS	DepMap CRISPR Gene Dependency	1.0	3.22761
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00338687
Perturb_17190_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	3.20155
Perturb_10880_KO_Thbs1_SRP276889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.34981
Perturb_8676_KD_ZNF281_SRP251817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.7806
OAZ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0062924
Perturb_5431_KD_IGFBP3_SRP377970	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.7306
Perturb_15483_OE_ERG_SRP142174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
T84	DepMap CRISPR Gene Dependency	1.0	2.34075
PDE8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00565554
Perturb_10444_KO_miR29b_SRP075398	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.41214
Perturb_14556_KO_KLF5_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5008_Mut_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.97607
NB10	DepMap CRISPR Gene Dependency	1.0	5.08662
ADAM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630556
STS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00479019
Perturb_18394_KO_Ivl_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.68804
Perturb_17174_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Immune Thrombocytopenic Purpura	DisGeNET Gene-Disease Associations	1.0	null
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.60566
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_422_KD_FOXM1_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BCL9L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467224
NB17	DepMap CRISPR Gene Dependency	1.0	2.87745
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9798_OE_XPO4_SRP328169	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_9799_OE_XPO4_SRP328169	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_17181_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
LSP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570974
Perturb_18148_KO_Ikbkb_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.88314
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_16950_OE_GATA6_SRP235000	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.55722
SUDHL10	DepMap CRISPR Gene Dependency	1.0	7.68384
TRIM22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00504029
Perturb_423_KO_TAF15_SRP388817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.4157
Perturb_16538_KD_Bcl9/Bcl9l_ERP113260	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59369
Lyme Disease	DisGeNET Gene-Disease Associations	1.0	null
KYSE150	DepMap CRISPR Gene Dependency	1.0	3.22795
BTNL8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00421354
CDON	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509192
Perturb_17196_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DAPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486921
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EXTL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00639146
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.89997
HIPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568409
Perturb_17188_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_17189_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5010_KO_Sall4_ERP122174	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.1792
ZNF512	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484969
Paratuberculosis	DisGeNET Gene-Disease Associations	1.0	null
COG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00773918
PYGM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00714497
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17172_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_17173_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Perturb_15789_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.61098
TEAD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00866184