association	dataset	threshold value	standardized value
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO Biological Process Annotations 2025	1.0	null
protein localization to organelle	GO Biological Process Annotations 2025	1.0	null
response to endoplasmic reticulum stress	GO Biological Process Annotations 2023	1.0	null
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
protein localization to mitochondrion	GO Biological Process Annotations 2025	1.0	null
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
protein autoubiquitination	GO Biological Process Annotations 2025	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2792_KO_LATS1/LATS2_SRP331116	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
protein polyubiquitination	GO Biological Process Annotations 2023	1.0	null
Perturb_1119_OE_RUNX1_ERP106519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.6278
Perturb_13716_KO_BAP1_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.71146
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
protein polyubiquitination	GO Biological Process Annotations 2025	1.0	null
protein localization to mitochondrion	GO Biological Process Annotations 2023	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
proteasomal protein catabolic process	GO Biological Process Annotations 2023	1.0	null
Perturb_7659_KD_CTCF/CTCF_SRP128556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.8207
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
Perturb_13714_KO_ASXL3_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.91768
protein K29-linked ubiquitination	GO Biological Process Annotations 2025	1.0	null
Perturb_13660_KD_FOXO3_SRP325840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.03899
proteasome-mediated ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
response to endoplasmic reticulum stress	GO Biological Process Annotations 2025	1.0	null
Perturb_2917_KD_FOXO3_SRP325840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.4961
protein autoubiquitination	GO Biological Process Annotations 2023	1.0	null
Perturb_9794_KD_FOXO3_SRP325840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.0596
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
protein K29-linked ubiquitination	GO Biological Process Annotations 2023	1.0	null
Perturb_7657_KD_CTCF_SRP128556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88962
Perturb_8829_KD_KCNN4_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2023	1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
intrinsic apoptotic signaling pathway	GO Biological Process Annotations 2023	1.0	null
protein localization to organelle	GO Biological Process Annotations 2023	1.0	null
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO Biological Process Annotations 2023	1.0	null
proteasomal protein catabolic process	GO Biological Process Annotations 2025	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
ubiquitin-dependent protein catabolic process	GO Biological Process Annotations 2025	1.0	null
intrinsic apoptotic signaling pathway	GO Biological Process Annotations 2025	1.0	null
protein K63-linked ubiquitination	GO Biological Process Annotations 2023	1.0	null
protein K63-linked ubiquitination	GO Biological Process Annotations 2025	1.0	null
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null