association dataset threshold value standardized value LAMA84 CCLE Cell Line Gene CNV Profiles 1.0 1.50254 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975876 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912386 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.66373 FADU COSMIC Cell Line Gene CNV Profiles -1.0 -3.05196 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19495 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.56538 JAK2_mutant_40_GSE11003 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.53424 MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03041 IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78084 SNU620 CCLE Cell Line Gene CNV Profiles 1.0 1.61836 SKNMC CCLE Cell Line Gene CNV Profiles 1.0 2.49206 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.950231 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90636 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912386 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48996 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.3373 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43796 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.999228 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11522 MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 0.99986 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.12423 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -1.52894 LU99 CCLE Cell Line Gene CNV Profiles -1.0 -1.5235 HPAFII CCLE Cell Line Gene CNV Profiles -1.0 -1.88885 HUH1 CCLE Cell Line Gene CNV Profiles -1.0 -1.3776 MELAS - Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes_Muscle - Striated (Skeletal) (MMHCC)_GSE1462 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.45642 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 PANC1 BioGPS Cell Line Gene Expression Profiles 1.0 1.3813 SubthalamicNucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.03869 HCC2814 CCLE Cell Line Gene CNV Profiles -1.0 -1.54822 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.76591 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851646 Skeletal Muscle Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02597 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06327 HCC1599 CCLE Cell Line Gene CNV Profiles -1.0 -2.33477 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.082664 HCT15 BioGPS Cell Line Gene Expression Profiles -1.0 -1.07835 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912386 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33552 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.995302 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.885762 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90552 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37076 SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.866448 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78579 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05619 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.72945 LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TCF4 MotifMap Predicted Transcription Factor Targets 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46816 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886429 COLO684 CCLE Cell Line Gene CNV Profiles 1.0 1.74285 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19495 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.081 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928143 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -2.09235 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43796 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1945 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90182 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56163 SRC_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.086542 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43796 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.356 HCC70 COSMIC Cell Line Gene CNV Profiles -1.0 -3.05196 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.332 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37129 NCIH1092 CCLE Cell Line Gene CNV Profiles 1.0 1.35462 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937496 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843991 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10548 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.050382 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68797 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.867417 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.249215 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851646 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00802 COLO680N CCLE Cell Line Gene CNV Profiles -1.0 -1.35587 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.501569 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912386 all GWASdb SNP-Phenotype Associations 1.0 0.028011 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8508 COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16335 TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.958468 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48996 CHAGO-K-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.15465 JHH1 CCLE Cell Line Gene CNV Profiles 1.0 1.78344 GDM1 CCLE Cell Line Gene CNV Profiles 1.0 1.45638 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 HCC1428 CCLE Cell Line Gene CNV Profiles -1.0 -1.86493 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05739 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26029 Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.59294 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.90983 MOLM13 CCLE Cell Line Gene CNV Profiles 1.0 1.94968 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928069 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928069 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33832 disease GWASdb SNP-Disease Associations 1.0 0.023582 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22596 Amygdala BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.959634 HEK 293 T-rex BioGPS Cell Line Gene Expression Profiles 1.0 1.44906 SW1116 CCLE Cell Line Gene CNV Profiles -1.0 -1.61134 MALME 3M BioGPS Cell Line Gene Expression Profiles 1.0 0.959056 mood disorder GWASdb SNP-Disease Associations 1.0 0.26857 TE441T CCLE Cell Line Gene CNV Profiles 1.0 1.56421 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33832 MCF7 BioGPS Cell Line Gene Expression Profiles -1.0 -1.0561 HCC366 CCLE Cell Line Gene CNV Profiles -1.0 -1.35559 SYNCRIP_OE_GDS1806_82_human_T-lymphocytes from normal donors were activated with anti-CD3 and IL2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.928069 mania GWASdb SNP-Phenotype Associations 1.0 0.428141 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.885762 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31563 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.037694 OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.78137 OVCAR8 BioGPS Cell Line Gene Expression Profiles -1.0 -1.41878 HCC1171 CCLE Cell Line Gene CNV Profiles -1.0 -1.54881 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43743 CCRT CEM BioGPS Cell Line Gene Expression Profiles 1.0 2.41625 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.912386 PK1 CCLE Cell Line Gene CNV Profiles -1.0 -3.16898 DDR1_knockdown_169_GSE39207 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.07403 BC3C CCLE Cell Line Gene CNV Profiles 1.0 1.51345 DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.864996 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31563 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.843991 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 HT29 CCLE Cell Line Gene CNV Profiles -1.0 -1.88485 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57337 depression GWASdb SNP-Phenotype Associations 1.0 0.345797 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20997 disease of mental health GWASdb SNP-Disease Associations 1.0 0.040302 NOMO1 CCLE Cell Line Gene CNV Profiles 1.0 1.35676 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1397 A204 BioGPS Cell Line Gene Expression Profiles 1.0 1.01306 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.842502 SW1417 CCLE Cell Line Gene CNV Profiles -1.0 -1.76051 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.995302 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17544 SNU61 CCLE Cell Line Gene CNV Profiles -1.0 -1.54543 DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.15241 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70474 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43743 rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.312552 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8508 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20997 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25337 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37129 MEK_OE_GDS1925_165_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90594 FADU CCLE Cell Line Gene CNV Profiles -1.0 -2.59674 TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.53557 BT549 CCLE Cell Line Gene CNV Profiles 1.0 1.81088 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.428141 Primary hematopoietic stem cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.944063 HCC202 CCLE Cell Line Gene CNV Profiles -1.0 -1.39155 HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.908878 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.974266 KURAMOCHI CCLE Cell Line Gene CNV Profiles -1.0 -1.45547 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -1.6618 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08692 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41902 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.83037 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -2.21179 ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.484615 HCC38 CCLE Cell Line Gene CNV Profiles -1.0 -1.81812 JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55496 cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31514 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26029 OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 JHOS-4 COSMIC Cell Line Gene CNV Profiles -1.0 -3.05196 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998246 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16707 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.60873 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05828 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.028027 Essential Thrombocytemia_Thrombocyte_GSE2006 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.82293 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68797 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90594 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.974266 astrocytes BioGPS Cell Line Gene Expression Profiles -1.0 -2.08727 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41902 HH CCLE Cell Line Gene CNV Profiles 1.0 1.38983 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05619 ECC10 CCLE Cell Line Gene CNV Profiles 1.0 1.78554 KCL22 CCLE Cell Line Gene CNV Profiles 1.0 2.2471 DANG CCLE Cell Line Gene CNV Profiles -1.0 -1.45547 K562 BioGPS Cell Line Gene Expression Profiles 1.0 0.888202 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11249 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927785 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927785 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.25573 znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.140669 WSU-DLCL2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -1.27179 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.914348 SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.944204 IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51807 FetalThyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.1935 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.22727