association dataset threshold value standardized value RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SBC5 CCLE Cell Line Gene CNV Profiles -1.0 -1.92612 arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.208194 HMCB CCLE Cell Line Gene Expression Profiles -1.0 -1.74374 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.52228 HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67023 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15698 GRANTA519 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 PANC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.45037 NCIH2087 CCLE Cell Line Gene Expression Profiles -1.0 -2.2493 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6488 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00124 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23588 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.35835 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.277114 MHHCALL2 CCLE Cell Line Gene CNV Profiles 1.0 1.67177 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.196312 SNU899 CCLE Cell Line Gene Expression Profiles 1.0 1.41408 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1207 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6488 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5668 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.15903 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18542 obstructive lung disease GWASdb SNP-Disease Associations 1.0 0.635441 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 1.23556 lymphopenia GWASdb SNP-Disease Associations 1.0 1.06059 neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.275076 abnormality of the nose GWASdb SNP-Phenotype Associations 1.0 0.629202 G124 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.841078 SKLU1 CCLE Cell Line Gene Expression Profiles 1.0 1.45208 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64359 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09833 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03825 MOLT16 CCLE Cell Line Gene Expression Profiles 1.0 1.39465 AN3CA CCLE Cell Line Gene Expression Profiles 1.0 1.83581 CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0119 UMRC6 CCLE Cell Line Gene CNV Profiles -1.0 -1.3316 CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1648 CCLE Cell Line Gene CNV Profiles -1.0 -2.36273 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 SW480 CCLE Cell Line Gene Expression Profiles 1.0 1.82621 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.446909 abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.617835 HCC1143 CCLE Cell Line Gene CNV Profiles 1.0 1.46006 NCIH69 CCLE Cell Line Gene Expression Profiles 1.0 3.40796 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null kidney disease GWASdb SNP-Disease Associations 1.0 0.863933 cognitive impairment GWASdb SNP-Phenotype Associations 1.0 0.522136 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955806 KLM1 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1568 CCLE Cell Line Gene CNV Profiles -1.0 -2.09225 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01054 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883189 OCILY3 CCLE Cell Line Gene CNV Profiles 1.0 2.04753 CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.62907 abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.07164 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.883189 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.83897 HNF4A ENCODE Transcription Factor Targets 1.0 null SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997552 abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.163835 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15263 SHSY5Y CCLE Cell Line Gene CNV Profiles -1.0 -1.36065 HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS944T CCLE Cell Line Gene Expression Profiles -1.0 -1.54077 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828727 HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -3.13876 CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null bronchial disease GWASdb SNP-Disease Associations 1.0 1.06059 leukopenia GWASdb SNP-Disease Associations 1.0 0.420455 HOXD9_01_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.76168 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HH CCLE Cell Line Gene Expression Profiles 1.0 1.40406 HCC1897 CCLE Cell Line Gene Expression Profiles -1.0 -1.88113 HCC15 CCLE Cell Line Gene Expression Profiles 1.0 1.64206 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null GSS CCLE Cell Line Gene CNV Profiles 1.0 1.45267 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KE39 CCLE Cell Line Gene Expression Profiles -1.0 -1.79317 CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937775 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 0.092915 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.850197 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SC-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.09627 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17409 abnormality of the mouth GWASdb SNP-Phenotype Associations 1.0 0.146982 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10467 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.55841 viral infectious disease GWASdb SNP-Disease Associations 1.0 0.299688 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.064864 NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.74896 abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.218622 CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.983131 human immunodeficiency virus infectious disease GWASdb SNP-Disease Associations 1.0 1.23556 ZR751 CCLE Cell Line Gene Expression Profiles 1.0 2.23651 ST486 CCLE Cell Line Gene Expression Profiles 1.0 1.59699 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU423 CCLE Cell Line Gene Expression Profiles -1.0 -1.83657 disease of mental health GWASdb SNP-Disease Associations 1.0 0.074099 CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49547 CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.128402 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15315 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLDN1_OE_GDS3510_393_human_CL1-5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09833 CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH520 CCLE Cell Line Gene Expression Profiles -1.0 -2.38333 hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.201579 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929376 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04855 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 2.0085 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.062474 SKMEL31 CCLE Cell Line Gene CNV Profiles -1.0 -2.00452 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30607 disease GWASdb SNP-Disease Associations 1.0 0.096732 HCT15 CCLE Cell Line Gene Expression Profiles -1.0 -1.81907 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71869 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25349 DB CCLE Cell Line Gene Expression Profiles 1.0 1.64617 NCIH69 CCLE Cell Line Gene CNV Profiles 1.0 1.87448 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04123 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.264722 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 HNF4A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GRANTA-519 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 tauopathy GWASdb SNP-Disease Associations 1.0 0.652472 HCC202 CCLE Cell Line Gene Expression Profiles 1.0 1.53293 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.235281 SNUC2A CCLE Cell Line Gene Expression Profiles -1.0 -1.6169 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null asthma GWASdb SNP-Disease Associations 1.0 1.06059 abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.208194 all GWASdb SNP-Phenotype Associations 1.0 0.069901 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39778 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.615118 TP63_01_200 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.61778 PANC0213 CCLE Cell Line Gene Expression Profiles -1.0 -1.82057 REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null COLO741 CCLE Cell Line Gene CNV Profiles -1.0 -1.55025 abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.043344 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82445 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45259 RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null RERFLCMS CCLE Cell Line Gene CNV Profiles -1.0 -1.72553 CAL120 CCLE Cell Line Gene Expression Profiles -1.0 -1.51254 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.978959 KARPAS-422 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.46193 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06807 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03245 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of neutrophils GWASdb SNP-Phenotype Associations 1.0 1.08173 USF2 ENCODE Transcription Factor Targets 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3694 oral cleft GWASdb SNP-Phenotype Associations 1.0 0.587158 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.826979 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67135 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89729 CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null immune system cancer GWASdb SNP-Disease Associations 1.0 0.244182 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10467 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.134982 leukemia GWASdb SNP-Disease Associations 1.0 1.06059 CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.163835 H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DMS-53 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.058517 KMS26 CCLE Cell Line Gene Expression Profiles 1.0 1.42735 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 1.06059 H2BK20ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null physical disorder GWASdb SNP-Disease Associations 1.0 0.373207 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.077969 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872414 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955806 CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH460 CCLE Cell Line Gene CNV Profiles -1.0 -1.47449 NCIH854 CCLE Cell Line Gene Expression Profiles 1.0 2.02661 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.130736 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15263 RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.91394 vascular disease GWASdb SNP-Disease Associations 1.0 0.135823 HNF4A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10467 abnormality of lymphocytes GWASdb SNP-Phenotype Associations 1.0 0.929216 H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15613 lung disease GWASdb SNP-Disease Associations 1.0 0.40781 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.269911 NCI-H1963 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 C-33 A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946159 CORL95 CCLE Cell Line Gene CNV Profiles 1.0 1.77919 TE6 CCLE Cell Line Gene CNV Profiles -1.0 -1.38416 CLDN1_OE_GDS3510_31_human_CL1-5 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.757258 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45859 abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.218622 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.983016 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.50175 SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33836 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45859 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09833 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10467 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42977 lymphoma GWASdb SNP-Disease Associations 1.0 1.06059 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -2.01846 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83157 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98258 PTEN_KD_GDS2958_101_human_SKBR-3 MAMMARY ADENOCARCINOMA cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOS3 CCLE Cell Line Gene CNV Profiles -1.0 -1.7346 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.06771 urinary system disease GWASdb SNP-Disease Associations 1.0 0.202006 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18542 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895494 C170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.92801 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.476654 DETROIT562 CCLE Cell Line Gene CNV Profiles -1.0 -1.68104 morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.080642 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.983016 RKN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875078 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34087 Airflow obstruction GWAS Catalog SNP-Phenotype Associations 1.0 0.246511 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80674 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.181883 HNF4G ENCODE Transcription Factor Targets 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null alzheimer's disease GWASdb SNP-Disease Associations 1.0 0.652472 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null alzheimer disease GWASdb SNP-Phenotype Associations 1.0 0.55667 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.111753 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.056792 SNU449 CCLE Cell Line Gene Expression Profiles 1.0 1.80043 CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW948 CCLE Cell Line Gene CNV Profiles -1.0 -1.36228 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997552 chronic obstructive pulmonary disease GWASdb SNP-Disease Associations 1.0 1.21996 NCIH82 CCLE Cell Line Gene CNV Profiles -1.0 -1.4573 SNU213 CCLE Cell Line Gene CNV Profiles -1.0 -2.55985 CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923825 CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null respiratory system disease GWASdb SNP-Disease Associations 1.0 0.384384 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.20531 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38804 RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCM6 CCLE Cell Line Gene Expression Profiles -1.0 -1.90798 HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1292 abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.164971 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15263 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.098637 CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null NCIH1693 CCLE Cell Line Gene CNV Profiles 1.0 1.54577 lymphoma GWASdb SNP-Phenotype Associations 1.0 0.929216 RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orofacial cleft GWASdb SNP-Disease Associations 1.0 0.685245 hematologic cancer GWASdb SNP-Disease Associations 1.0 0.244182 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42875 CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.056407 RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34031 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06807 CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the face GWASdb SNP-Phenotype Associations 1.0 0.189568 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09784 KYSE270 CCLE Cell Line Gene Expression Profiles -1.0 -1.54389 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-330 COSMIC Cell Line Gene CNV Profiles -1.0 -3.36169 abnormality of myeloid leukocytes GWASdb SNP-Phenotype Associations 1.0 0.253379 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKCO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.36891 RAD21 ENCODE Transcription Factor Targets 1.0 null abnormality of higher mental function GWASdb SNP-Phenotype Associations 1.0 0.245175 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.161431 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.873668 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.235281 type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.523916 NCIH1395 CCLE Cell Line Gene Expression Profiles 1.0 2.65492 MINO CCLE Cell Line Gene CNV Profiles 1.0 1.50783 LN215 CCLE Cell Line Gene Expression Profiles -1.0 -2.01937 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15263 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.823969 OVISE CCLE Cell Line Gene CNV Profiles -1.0 -1.62431 CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null A1207 CCLE Cell Line Gene Expression Profiles -1.0 -1.52857 abnormality of granulocytes GWASdb SNP-Phenotype Associations 1.0 0.34906 OCILY3 CCLE Cell Line Gene Expression Profiles 1.0 1.35943 BALL-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dementia GWASdb SNP-Disease Associations 1.0 0.3675 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2218 CCLE Cell Line Gene Expression Profiles 1.0 1.69404 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21807 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03825 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null leukocyte disease GWASdb SNP-Disease Associations 1.0 0.371013 CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.828727 KMS26 CCLE Cell Line Gene CNV Profiles 1.0 1.41224 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PATU8988S CCLE Cell Line Gene Expression Profiles 1.0 1.9625 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.35131 CTCF_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34031 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null OCIMY7 CCLE Cell Line Gene CNV Profiles 1.0 1.44335 sensory system disease GWASdb SNP-Disease Associations 1.0 0.729823 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.695366 BICR6 CCLE Cell Line Gene Expression Profiles 1.0 1.35632 CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null obstructive lung disease GWASdb SNP-Phenotype Associations 1.0 1.0674 COLO668 CCLE Cell Line Gene Expression Profiles 1.0 2.40871 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.897064 coronary artery disease GWASdb SNP-Disease Associations 1.0 0.55923 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09833 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30607 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42875 SUDHL10 CCLE Cell Line Gene CNV Profiles -1.0 -2.20307 cancer GWASdb SNP-Disease Associations 1.0 0.078268 NCIH2085 CCLE Cell Line Gene Expression Profiles 1.0 2.14962 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.98258 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22662 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null disease by infectious agent GWASdb SNP-Disease Associations 1.0 0.192062 BCLAF1_01_214 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.75426 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.23203 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884056 PANC1005 CCLE Cell Line Gene CNV Profiles -1.0 -1.8198 NCIH1963 CCLE Cell Line Gene CNV Profiles 1.0 2.47855 HCC1500 CCLE Cell Line Gene CNV Profiles 1.0 1.73965 PATU8988S CCLE Cell Line Gene CNV Profiles -1.0 -1.51473 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19898 JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 2.18087 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null organ system cancer GWASdb SNP-Disease Associations 1.0 0.084967 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null SW1116 CCLE Cell Line Gene Expression Profiles 1.0 1.63065 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07523 CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.079351 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2186 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00966 A4FUK CCLE Cell Line Gene Expression Profiles 1.0 1.63944 NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 2.24002 SLR26 CCLE Cell Line Gene Expression Profiles -1.0 -1.63208 CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09784 UMRC2 CCLE Cell Line Gene CNV Profiles -1.0 -1.48831 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.196312 PTEN_01_303 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.17675 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mel-18_KD_GDS2724_103_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null YAP_OE_GDS3220_32_human_MCF10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03245 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872414 OCIMY5 CCLE Cell Line Gene CNV Profiles 1.0 1.89015 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.106212 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.40781 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.068648 diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.255567 CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of body height GWASdb SNP-Phenotype Associations 1.0 0.675718 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25549 DANG CCLE Cell Line Gene CNV Profiles -1.0 -1.64249 CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALK_KD_GDS2724_105_human_DAOY medulloblastoma cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hypertension GWASdb SNP-Disease Associations 1.0 0.717397 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.29275 artery disease GWASdb SNP-Disease Associations 1.0 0.18104 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.264722 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.076314 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.39837 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.17933