association dataset threshold value standardized value NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.08915 hsa-miR-548h TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54603 ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A619-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20384 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00517 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cell wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.357086 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles 1.0 2.30416 JARID2-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Main olfactory bulb, granule layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.09238 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.64909 Lipid phosphate phosphatase-related protein type 5 InterPro Predicted Protein Domain Annotations 1.0 null cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32817 intermediate stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70082 uterus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.893302 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_ASCL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054445 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K23ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47202 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-190b TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTBP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAPK1_knockdown_45_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.62924 SNU308 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058628 hsa-miR-4769-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20361 placenta HPA Tissue Protein Expression Profiles -1.0 -1.23747 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-495 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ECC12 CCLE Cell Line Gene Expression Profiles -1.0 -2.2721 AR ChEA Transcription Factor Targets 1.0 null AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20501 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22966 H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of filopodium assembly GO Biological Process Annotations 2023 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA(16:0/18:2(9Z,12Z)) HMDB Metabolites of Enzymes 1.0 null SIMA CCLE Cell Line Gene Expression Profiles 1.0 1.9885 hsa-miR-520a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.897495 phospholipid metabolic process GO Biological Process Annotations 2023 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.08637 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58938 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 127399 DepMap CRISPR Gene Dependency 1.0 3.54727 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27383 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4903-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormal heart morphology MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04729 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48203 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25644 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.836247 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 0.699006 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal peduncular cortex, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09219 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6003-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-544 TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.993019 MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08376 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38128 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15273 hsa-miR-548j TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02493 Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.03022 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02493 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the abdomen GWASdb SNP-Phenotype Associations 1.0 0.046113 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.88784 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05637 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46943 KELLY CCLE Cell Line Gene CNV Profiles 1.0 1.3316 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OB inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94098 phosphatase activity GO Molecular Function Annotations 2023 1.0 null musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.071582 ZNF143_02_59 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.35755 CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_iPS-15b Roadmap Epigenomics Histone Modification Site Profiles 1.0 null T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null characterized GeneRIF Biological Term Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.921714 H3K27ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.257154 CTCF ENCODE Transcription Factor Targets 1.0 null dephosphorylation GO Biological Process Annotations 2023 1.0 null midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.299 Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00414 hsa-miR-4491 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 7 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 1.43176 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932262 septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0746 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7229-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20325 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null enlarged thymus MGI Mouse Phenotype Associations 2023 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.195148 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.247 ECC10 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the skeletal system GWASdb SNP-Phenotype Associations 1.0 0.053679 hsa-miR-556-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.069137 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30143 decreased thigmotaxis MGI Mouse Phenotype Associations 2023 1.0 null EGR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14923_Mut_Atxn3_SRP155020 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.50365 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_2467_KO_NAT10_SRP388804 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.31572 Obesity-related traits GWAS Catalog SNP-Phenotype Associations 1.0 0.042592 anophthalmia MGI Mouse Phenotype Associations 2023 1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29665 periventricular stratum of r6Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62017 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.948541 fetal GeneRIF Biological Term Annotations 1.0 null Perturb_4468_KO_Cnr1_SRP346447 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.66276 CMK86 CCLE Cell Line Gene Expression Profiles -1.0 -1.77292 Perturb_15804_KO_Atf3_SRP350242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07145 E2F6 ENCODE Transcription Factor Targets 1.0 null Smoking DisGeNET Gene-Phenotype Associations 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NP8 DepMap CRISPR Gene Dependency 1.0 2.63813 Perturb_4151_KO_Csmd3_SRP343147 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.45756 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01767 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.951369 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.997132 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null carious teeth GWASdb SNP-Phenotype Associations 1.0 1.00059 tauopathy GWASdb SNP-Disease Associations 1.0 0.620518 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 PA(16:0/16:0) HMDB Metabolites of Enzymes 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15312 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 9505BIK DepMap CRISPR Gene Dependency 1.0 2.19059 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19976 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852276 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.866482 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01098 hsa-miR-4666-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 alzheimer's disease GWASdb SNP-Disease Associations 1.0 0.620518 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35019 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2002 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JZ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal thymus morphology MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-1257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.886535 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958483 hsa-miR-645 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22797 E2F6 JASPAR Predicted Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLR26 CCLE Cell Line Gene Expression Profiles 1.0 1.42964 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.45373 8MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.62046 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77814 BFTC-909 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.24598 CHD7 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.039961 hsa-miR-4427 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 cholecalciferol_mus musculus_gpl6246_gse41184 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null arthritis GWASdb SNP-Disease Associations 1.0 0.279713 mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27348 cellular_component GO Cellular Component Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56067 G401 CCLE Cell Line Gene Expression Profiles 1.0 1.62204 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null artery disease GWASdb SNP-Disease Associations 1.0 0.086798 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prostate HPA Tissue Protein Expression Profiles -1.0 -1.23747 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.949174 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS-53 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 PC-3_[JPC-3] COSMIC Cell Line Gene Mutation Profiles 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.73493 hsa-miR-4642 TargetScan Predicted Conserved microRNA Targets 1.0 0.181316 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3668 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.833864 mantle zone of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97627 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5377-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE270 DepMap CRISPR Gene Dependency 1.0 2.33643 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.081257 Hypb_Deficiency_GDS3641_522_mouse_Yolk sac from E9 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MFE296 DepMap CRISPR Gene Dependency 1.0 4.69151 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04224 spleen GTEx Tissue Gene Expression Profiles -1.0 -0.945887 dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2636 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77318 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKRC31 CCLE Cell Line Gene Expression Profiles -1.0 -1.53924 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29116 thyroid gland HPA Tissue Protein Expression Profiles 1.0 0.699006 D341MED CCLE Cell Line Gene Expression Profiles 1.0 1.45303 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51404 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.76574 RERFLCKJ CCLE Cell Line Gene CNV Profiles 1.0 1.77343 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65039 catalytic activity GO Molecular Function Annotations 2015 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.06466 PA(16:0/18:1(9Z)) HMDB Metabolites of Enzymes 1.0 null PA(18:1(11Z)/18:1(9Z)) HMDB Metabolites of Enzymes 1.0 null SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4677-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 alzheimer disease GWASdb SNP-Phenotype Associations 1.0 0.526896 hsa-miR-128 TargetScan Predicted Conserved microRNA Targets 1.0 0.140752 Lung adenocarcinoma_LUAD_TCGA-50-5930-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15080_KD_Chd8_SRP354984 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.74801 positive geotaxis MGI Mouse Phenotype Associations 2023 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.183454 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Parafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23102 42MGBA DepMap CRISPR Gene Dependency 1.0 2.11538 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGBC52TKB DepMap CRISPR Gene Dependency 1.0 2.32301 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -0.90354 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0956 hsa-miR-548c-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r7 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57076 mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41808 retromammillary area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03867 Dental caries GWAS Catalog SNP-Phenotype Associations 1.0 0.165905 A101D COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased susceptibility to pharmacologically induced seizures MGI Mouse Phenotype Associations 2023 1.0 null superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70192 NCIH82 CCLE Cell Line Gene Expression Profiles 1.0 1.5394 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27275 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02957 DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.91035 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40803 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.183454 accumbens nucleus, shell domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18317 H3K4me1_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Duration Of Sleep DisGeNET Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4162-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LS180 DepMap CRISPR Gene Dependency 1.0 2.56273 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45039 CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04249 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-631 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 EP300 ENCODE Transcription Factor Targets 1.0 null Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5216 NCI-H1581 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-27a TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.06933 SUZ12-16625203-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051262 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20931 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.85185 abnormality of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.223079 SNU449 DepMap CRISPR Gene Dependency 1.0 2.57708 abnormal testis morphology MGI Mouse Phenotype Associations 2023 1.0 null NCIH838 CCLE Cell Line Gene CNV Profiles 1.0 2.20766 Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01898 hsa-miR-548ak TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 hsa-miR-4803 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SMAD4-21741376-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null SCABER CCLE Cell Line Gene CNV Profiles 1.0 1.47587 H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null type GeneRIF Biological Term Annotations 1.0 null CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.842818 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51984 SNUC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.93575 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4225 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18679 interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36462 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 library GeneRIF Biological Term Annotations 1.0 null Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06214 SF268 DepMap CRISPR Gene Dependency 1.0 2.35177 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.092575 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56968 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SNU503 CCLE Cell Line Gene CNV Profiles -1.0 -2.50818 H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-647 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 parahippocampal gyrus, right, bank of the cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895903 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.34796 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.391176 abnormal bone structure MGI Mouse Phenotype Associations 2023 1.0 null Mesothelioma_MESO_TCGA-TS-A7P6-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null impaired passive avoidance behavior MGI Mouse Phenotype Associations 2023 1.0 null abnormal eye morphology MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-524-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06889 CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25951 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bone inflammation disease GWASdb SNP-Disease Associations 1.0 0.244792 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32025 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.24211 LCLC97TM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.48256 vacuole LOCATE Predicted Protein Localization Annotations 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDK4_knockdown_225_GSE8866 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.21079 abnormality of the oral cavity GWASdb SNP-Phenotype Associations 1.0 0.271442 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.467959 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UO-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1267 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3614 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5365-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.889004 KELLY CCLE Cell Line Gene Expression Profiles 1.0 3.40787 r9 portion of vagal motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41808 Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acid GeneRIF Biological Term Annotations 1.0 null hsa-miR-3671 TargetScan Predicted Conserved microRNA Targets 1.0 0.119151 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-539 TargetScan Predicted Conserved microRNA Targets 1.0 0.159923 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null LB1047RCC DepMap CRISPR Gene Dependency 1.0 2.81453 hsa-miR-4728-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50186 morphine_mus musculus_gpl6105_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null rheumatoid arthritis GWASdb SNP-Phenotype Associations 1.0 0.577563 SUZ12 ENCODE Transcription Factor Targets 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18679 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.23476 icSARS CoV_24Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.37196 OB mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92775 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72907 Sarcoma_SARC_TCGA-DX-A3M1-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BHY CCLE Cell Line Gene CNV Profiles 1.0 2.59998 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nodulus (X), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53705 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20309 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25562 LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22335 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTBP2 ENCODE Transcription Factor Targets 1.0 null ZC3H11A_02_44 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.39232 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6828 accumbens nucleus, core domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06291 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SHSY5Y CCLE Cell Line Gene Expression Profiles 1.0 1.88026 RERFLCAD1 CCLE Cell Line Gene Expression Profiles -1.0 -2.16952 hsa-miR-579 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.31677 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04526 hsa-miR-4657 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 SCC25 CCLE Cell Line Gene CNV Profiles 1.0 2.36412 mantle zone of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0557 hsa-miR-1193 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 hsa-miR-4261 TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K23ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11943 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.64742 sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.011051 MDA-MB-361 COSMIC Cell Line Gene Mutation Profiles 1.0 null increased body weight GWASdb SNP-Phenotype Associations 1.0 0.855449 Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SRY ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27383 PC3 CCLE Cell Line Gene Expression Profiles 1.0 1.35493 functional abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.181043 hsa-miR-3688-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01252 intestinal disease GWASdb SNP-Disease Associations 1.0 0.234222 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3944-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02918 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07011 PA(18:1(11Z)/18:1(11Z)) HMDB Metabolites of Enzymes 1.0 null hsa-miR-4795-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6227-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_2481_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16128 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2BK20ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-29b TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null mantle zone of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65939 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-27b TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 EW22 DepMap CRISPR Gene Dependency 1.0 4.58017 KPNYN DepMap CRISPR Gene Dependency 1.0 5.19797 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852276 stomach HPA Tissue Protein Expression Profiles 1.0 0.699006 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4722-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 hsa-miR-29c TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 H3K27me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.843524 Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862504 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4224 hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.951205 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.102314 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97701 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1545 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04104 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24963 r7 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40274 SALE CCLE Cell Line Gene Expression Profiles -1.0 -1.47474 H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.844091 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.249719 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958483 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.826819 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null Main olfactory bulb, inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79533 LAN2 DepMap CRISPR Gene Dependency 1.0 4.94909 SNU1105 DepMap CRISPR Gene Dependency 1.0 2.52904 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.23018 bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.353776 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -2.07671 Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67111 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22652 NCIH1581 DepMap CRISPR Gene Dependency 1.0 2.22572 hsa-miR-4324 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YP-01A-21R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH841 DepMap CRISPR Gene Dependency 1.0 2.57494 CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04032 SKNDZ DepMap CRISPR Gene Dependency 1.0 2.03263 limb grasping MGI Mouse Phenotype Associations 2023 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-142-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.072809 Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null teeth hard tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38544 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null abnormality of the face GWASdb SNP-Phenotype Associations 1.0 0.209681 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051121 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH929 CCLE Cell Line Gene CNV Profiles -1.0 -1.79613 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17813 septostriatal transition area (accumbens) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05608 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.988323 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.896988 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU119 CCLE Cell Line Gene Expression Profiles -1.0 -1.63159 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null positive regulation of plasma membrane bounded cell projection assembly GO Biological Process Annotations 2023 1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-4738-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8517-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased susceptibility to weight gain MGI Mouse Phenotype Associations 2023 1.0 null r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04342 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.33849 primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19024 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null abnormality of the tongue GWASdb SNP-Phenotype Associations 1.0 0.563675 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20I-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dental caries GWASdb SNP-Disease Associations 1.0 1.14463 hsa-miR-4665-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 ALDH1A2_KO_GDS4836_289_mouse_posterior embryonic brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04444 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-372 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 abnormality of dental structure GWASdb SNP-Phenotype Associations 1.0 0.413807 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.137711 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05385 isoform GeneRIF Biological Term Annotations 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cdnas GeneRIF Biological Term Annotations 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null phosphatidate phosphatase activity GO Molecular Function Annotations 2023 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31864 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968019 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39865 r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77814 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1897 CCLE Cell Line Gene Expression Profiles -1.0 -1.47968 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsal part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20241 Perturb_14299_KO_Mef2c_SRP057560 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.9517 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HT1376 CCLE Cell Line Gene CNV Profiles -1.0 -2.78132 JUND ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A40U-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FU97 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15770_KO_Uxt_SRP240277 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 brain GTEx Tissue Gene Expression Profiles 1.0 2.02814 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.9565 Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00661 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.892921 CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CORL279 CCLE Cell Line Gene Expression Profiles 1.0 1.58957 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r8 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89016 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548ah TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fallopian tube HPA Tissue Protein Expression Profiles -1.0 -1.23747 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.452152 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6118 hsa-miR-1200 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 KDM4A ENCODE Transcription Factor Targets 1.0 null hsa-miR-3919 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00396 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17766 hsa-miR-1825 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3609 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.889934 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08418 r8 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23363 periventricular stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0644 CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.077514 globe disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45993 H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null olfactory bulb, principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97474 BACH1 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NO-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SUM229PE DepMap CRISPR Gene Dependency 1.0 2.64318 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of r5Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12511 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null r10 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52668 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.948704 external encapsulating structure COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.327581 LN215 CCLE Cell Line Gene Expression Profiles -1.0 -2.27785 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.962431 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null periventricular stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89016 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-548y TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32237 subiculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06868 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.09431 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.057747 hsa-miR-609 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 POLR2A ENCODE Transcription Factor Targets 1.0 null periventricular stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4471 rectum HPA Tissue Protein Expression Profiles 1.0 0.699006 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15532 Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16224 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4797-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 pituitary GTEx Tissue Gene Expression Profiles 1.0 0.958765 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-410 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68854 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903159 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37313 Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of neuron projection development GO Biological Process Annotations 2023 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02544 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.51364 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05142 central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51078 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.837473 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null HCE4 DepMap CRISPR Gene Dependency 1.0 2.76301 crohn's disease GWASdb SNP-Disease Associations 1.0 0.520364 superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22456 subethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81139 SMARCA4 ChEA Transcription Factor Targets 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887009 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SR786 CCLE Cell Line Gene CNV Profiles -1.0 -2.29911 gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.053647 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35139 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62578 NCOA2_KO_GDS5087_24_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TE-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4436b-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.241055 HCC202 DepMap CRISPR Gene Dependency 1.0 6.35533 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06127 LUDLU1 DepMap CRISPR Gene Dependency 1.0 3.01604 H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41984 phosphatase GeneRIF Biological Term Annotations 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44326 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35139 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8517_OE_CamkdeltaC_SRP287242 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.42807 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16173 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70128 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.249719 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34967 gastrointestinal system disease GWASdb SNP-Disease Associations 1.0 0.153367 eye disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.004714 mantle zone of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20351 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2707 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.43893 primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.566828 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04918 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.825081 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.936557 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42007 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7561 SP4 ENCODE Transcription Factor Targets 1.0 null small testis MGI Mouse Phenotype Associations 2023 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04864 Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31535 outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09238 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-625 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null abnormal urinary bladder morphology MGI Mouse Phenotype Associations 2023 1.0 null JARID2 ChEA Transcription Factor Targets 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4731-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null bladder GTEx Tissue Gene Expression Profiles 1.0 0.984977 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834009 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null teeth hard tissue disease GWASdb SNP-Disease Associations 1.0 1.14463 DAOY CCLE Cell Line Gene CNV Profiles 1.0 1.61136 abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.069066 vascular disease GWASdb SNP-Disease Associations 1.0 0.06267 hsa-miR-101 TargetScan Predicted Conserved microRNA Targets 1.0 0.131849 ChIP_SUZ12_16625203 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09665 r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27611 Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.369 PA(18:0/18:2(9Z,12Z)) HMDB Metabolites of Enzymes 1.0 null eye and adnexa disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31095 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null rheumatoid arthritis GWASdb SNP-Disease Associations 1.0 0.673994 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.43 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TE14 CCLE Cell Line Gene Expression Profiles -1.0 -2.49327 ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09478 VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.829087 hsa-miR-4682 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-302a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4051 SAOS-2 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31095 ChIP_SUZ12_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.175772 AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33624 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053681 COGN305 DepMap CRISPR Gene Dependency 1.0 5.97735 abnormal response to novel object MGI Mouse Phenotype Associations 2023 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.97238 Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10796 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.34126 p3 portion of paranigral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01124 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3383 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09153 ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41233 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27938 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00014 hsa-miR-377 TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null NB1 DepMap CRISPR Gene Dependency 1.0 3.54292 hsa-miR-190 TargetScan Predicted Conserved microRNA Targets 1.0 0.32519 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null hsa-miR-4803 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.91381 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null methylphenidate_mus musculus_gpl11180_gse33619 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H647 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.68596 AU565 DepMap CRISPR Gene Dependency 1.0 2.9875 hsa-miR-373 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K9me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27232 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943771 periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15553 dental caries DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 hsa-miR-4428 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68166 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03826 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.917439 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19522 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r6 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62137 C2BBE1 CCLE Cell Line Gene CNV Profiles -1.0 -1.39567 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_JARID2_20064375 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14667_KO_Sirt3_SRP277814 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.47429 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.359124 brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11254 NCIH524 CCLE Cell Line Gene Expression Profiles 1.0 1.48115 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57474 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anteroventral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00848 COGN278 DepMap CRISPR Gene Dependency 1.0 3.01696 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31581 hsa-miR-2964a-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 hsa-miR-1276 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 1.62667 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11009 H3K27me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mRNA_DPPA5A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 0.699006 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27524 chronic colitis GWASdb SNP-Phenotype Associations 1.0 0.350059 lysosome LOCATE Predicted Protein Localization Annotations 1.0 null Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25608 depression GWASdb SNP-Phenotype Associations 1.0 0.351913 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.18459 CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H1105 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0645 hsa-miR-4311 TargetScan Predicted Conserved microRNA Targets 1.0 0.219115 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-607 TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 hsa-miR-548b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.885723 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70797 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32863 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.996307 periventricular stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82614 H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38089 NCIH2887 DepMap CRISPR Gene Dependency 1.0 3.41278 hsa-miR-548w TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.60223 hsa-miR-1238 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053271 hsa-miR-4699-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null cloned GeneRIF Biological Term Annotations 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37826 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18062 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal seminal vesicle morphology MGI Mouse Phenotype Associations 2023 1.0 null crohn's disease GWASdb SNP-Phenotype Associations 1.0 0.443881 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 NAMALWA CCLE Cell Line Gene Expression Profiles -1.0 -1.55095 abnormality of the abdominal organs GWASdb SNP-Phenotype Associations 1.0 0.04994 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.876236 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.979228 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55415 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47191 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_13913_KD_SLC45A4_SRP173763 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.3696 H3K27me3_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KMS20 CCLE Cell Line Gene CNV Profiles -1.0 -1.45155 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16224 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11925 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null positive regulation of cell projection organization GO Biological Process Annotations 2023 1.0 null 42MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.3316 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20437 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.926396 coronary artery disease GWASdb SNP-Disease Associations 1.0 0.502949 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15532 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846431 intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.071221 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20825 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 2 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36527 morphological abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.099258 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12977 PHF8 ENCODE Transcription Factor Targets 1.0 null H3K27me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCE-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 integral component of membrane GO Cellular Component Annotations 2015 1.0 null periventricular stratum of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20592 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-577 TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.2166 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A4C1-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYC ChEA Transcription Factor Targets 1.0 null MM1S CCLE Cell Line Gene CNV Profiles -1.0 -1.54119 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.429443 RB1_KD_GSE50532_660_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null abnormal lymph node morphology MGI Mouse Phenotype Associations 2023 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03223 biological_process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5196-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null enzalutamide_homo sapiens_gpl570_gse44905 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.888497 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97402 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041267 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05871 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.79615 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958483 hsa-miR-3150a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Perturb_15377_KD_DAXX_SRP058098 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15796 TEAD4 ENCODE Transcription Factor Targets 1.0 null superficial stratum of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40104 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46083 short tibia MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cyclophosphamide_homo sapiens_gpl5104_gse27930 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05548 STAT3 ChEA Transcription Factor Targets 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00443 Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04344 periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38923 MXI1 ENCODE Transcription Factor Targets 1.0 null TE5 DepMap CRISPR Gene Dependency 1.0 2.60983 MM485 DepMap CRISPR Gene Dependency 1.0 3.76644 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6ZZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 superficial stratum of r4BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2251 abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.195148 MHHNB11 CCLE Cell Line Gene Expression Profiles 1.0 2.12869 gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 fusiform gyrus, right, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.930711 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04249 NCI-H1688 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60428 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XN-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.06702 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00443 NCI-H838 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 MM383 DepMap CRISPR Gene Dependency 1.0 2.41207 H4 DepMap CRISPR Gene Dependency 1.0 4.52915 CEBPB ENCODE Transcription Factor Targets 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRC-2_Deficiency_GDS5087_270_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null parahippocampal gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.859828 Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53312 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56324 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09106 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_16837_KO_Sufu/Spop_SRP145845 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.57735 COLO684 CCLE Cell Line Gene Expression Profiles 1.0 2.24999 hsa-miR-296-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 HEL9217 DepMap CRISPR Gene Dependency 1.0 3.07511 HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -1.62542 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain GeneRIF Biological Term Annotations 1.0 null WTX_OE_GDS4802_34_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01123 r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37272 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-922 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98255 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.227186 hsa-miR-4434 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Perturb_13938_KO_GPR91_SRP366683 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18503 EGR1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03046 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4885-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4727-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 periventricular stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41808 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-802 TargetScan Predicted Conserved microRNA Targets 1.0 0.199275 LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.60287 subiculum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.87028 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MFE280 CCLE Cell Line Gene CNV Profiles 1.0 1.4834 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-559 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52465 cdna GeneRIF Biological Term Annotations 1.0 null r4 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22249 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_3489_KD_lncOPC_SRP065742 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9128 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.934314 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053024 Phosphatidic acid phosphatase type 2/haloperoxidase InterPro Predicted Protein Domain Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07745 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.846199 abnormal locomotor behavior MGI Mouse Phenotype Associations 2023 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4353-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3283 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67Y-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-328 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 hsa-miR-298 TargetScan Predicted Conserved microRNA Targets 1.0 0.248923 periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08376 inflammatory bowel disease GWASdb SNP-Disease Associations 1.0 0.329388 brain HPA Tissue Gene Expression Profiles 1.0 2.21007 adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.699006 Nucleus of the solitary tract, commissural part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24908 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.94329 MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46462 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02091 19605494-TableS2 GeneSigDB Published Gene Signatures 1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18125 Nucleus of the solitary tract, gelatinous part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88361 lipid modification GO Biological Process Annotations 2023 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548d-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 RAD21 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.958483 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.14872 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07236 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3335-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.991247 nutrition disease GWASdb SNP-Disease Associations 1.0 0.411526 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5180-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-375 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40824 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.047182 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60519 CMLT1 DepMap CRISPR Gene Dependency 1.0 2.03811 hsa-miR-323-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 hsa-miR-4723-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28614 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.993937 EFE184 DepMap CRISPR Gene Dependency 1.0 3.34625 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10187 hsa-miR-340 TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19695 fetus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057868 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08948 JHH4 DepMap CRISPR Gene Dependency 1.0 2.00572 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64047 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23204 ChIP_MTF2_20144788 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PA(16:0/18:1(11Z)) HMDB Metabolites of Enzymes 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-708 TargetScan Predicted Conserved microRNA Targets 1.0 0.336728 hsa-miR-653 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.124058 H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46885 intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17137 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null periplasmic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.529618 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.02575 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16128 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05385 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13135 mouth disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 EZH2 ENCODE Transcription Factor Targets 1.0 null NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mood disorder GWASdb SNP-Disease Associations 1.0 0.279267 BHT101 CCLE Cell Line Gene CNV Profiles 1.0 1.38584 all GWASdb SNP-Phenotype Associations 1.0 0.050768 PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14618 CAL-72 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 abnormality of the intestine GWASdb SNP-Phenotype Associations 1.0 0.164252 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-513a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 CHP126 CCLE Cell Line Gene Expression Profiles 1.0 1.66293 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.09259 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null r9 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70082 TBP ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.853319 r8 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65814 WM2664 CCLE Cell Line Gene CNV Profiles -1.0 -1.35774 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.43319 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.913815 Perturb_9742_KO_Fxr_SRP241086 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.78803 neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.265403 hsa-miR-4446-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.131849 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.875333 KYSE-220 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.068508 lipid phosphatase activity GO Molecular Function Annotations 2023 1.0 null hsa-miR-4694-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 hsa-miR-548z TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 WM2664 CCLE Cell Line Gene Expression Profiles 1.0 1.37229 NCIH1869 CCLE Cell Line Gene CNV Profiles 1.0 1.35471 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53807 membrane LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-4447 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 J82 DepMap CRISPR Gene Dependency 1.0 2.03142 LN340 CCLE Cell Line Gene Expression Profiles -1.0 -1.55076 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPNRTBM1 CCLE Cell Line Gene Expression Profiles 1.0 1.75451 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17198 Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0994 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14971_KD_Crebbp_SRP154933 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.09607 KLM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.46086 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.829162 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.073486 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59712 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19229 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6491-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased physiological sensitivity to xenobiotic MGI Mouse Phenotype Associations 2023 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.57708 colitis GWASdb SNP-Phenotype Associations 1.0 0.350059 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 2.16976 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3604 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-302c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 gallbladder HPA Tissue Protein Expression Profiles 1.0 0.699006 mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-582-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.15008 Prostate adenocarcinoma_PRAD_TCGA-G9-6496-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4261 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C6-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-520b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.47531 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.39754 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.218509 connective tissue disease GWASdb SNP-Disease Associations 1.0 0.100451 mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37272 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.44372 increased cerebral infarct size MGI Mouse Phenotype Associations 2023 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35415 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.56008 SKNBE2 CCLE Cell Line Gene Expression Profiles 1.0 1.80902 Main olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76864 H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04138 Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNB75 DepMap CRISPR Gene Dependency 1.0 2.1756 MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.34324 dementia GWASdb SNP-Disease Associations 1.0 0.35889 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null heart muscle HPA Tissue Protein Expression Profiles 1.0 0.699006 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM185PE DepMap CRISPR Gene Dependency 1.0 6.06095 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1732 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4719 TargetScan Predicted Conserved microRNA Targets 1.0 0.274552 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_NANOG_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71289 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.64909 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.900424 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OB granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.33926 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27402 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04817 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMBOX1_02_58 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 5.04439 intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87292 E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-520c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17293 phosphatidic GeneRIF Biological Term Annotations 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAGE_knockout_269_GSE22873 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.67767 253JBV CCLE Cell Line Gene Expression Profiles 1.0 2.03583 SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22564 TE4 CCLE Cell Line Gene CNV Profiles -1.0 -2.05242 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.328628 Acute Myeloid Leukemia_LAML_TCGA-AB-2821-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parathyroid gland HPA Tissue Protein Expression Profiles 1.0 0.699006 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4868_KO_NEUROG3_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.77739 MKN74 CCLE Cell Line Gene CNV Profiles 1.0 1.93819 hsa-miR-302b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 HCC1599 CCLE Cell Line Gene CNV Profiles 1.0 1.51598 hsa-miR-361-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 inner CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.933943 mouth disease GWASdb SNP-Disease Associations 1.0 0.343758 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.19199 arthritis GWASdb SNP-Phenotype Associations 1.0 0.21091 small intestine HPA Tissue Protein Expression Profiles 1.0 2.30416 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null EKVX COSMIC Cell Line Gene Mutation Profiles 1.0 null HS746T CCLE Cell Line Gene Expression Profiles -1.0 -1.53395 r5 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82765 hsa-miR-3139 TargetScan Predicted Conserved microRNA Targets 1.0 0.257113 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OSRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.39092 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-3670 TargetScan Predicted Conserved microRNA Targets 1.0 0.265648 RBBP5 ENCODE Transcription Factor Targets 1.0 null 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.924034 G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.889934 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.00606 H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59712 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.966828 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52648 mRNA_SUZ12_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0056 periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36219 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4659a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.65586 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GRANTA519 CCLE Cell Line Gene CNV Profiles -1.0 -1.56985 CALR_KO_GDS3680_149_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MITF ChEA Transcription Factor Targets 1.0 null valproic acid_homo sapiens_gpl6883_gse26940 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Parasolitary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31383 SKMM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.68685 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCOA2_KO_GSE41558_19_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hsa-miR-3143 TargetScan Predicted Conserved microRNA Targets 1.0 0.226173 Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.248 H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SCC9 DepMap CRISPR Gene Dependency 1.0 3.84963 Perturb_13188_KO_Rbfox2_SRP216887 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.32672 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_2173_KO_Gsdmd_SRP366634 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.09391 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.22991 hsa-miR-1256 TargetScan Predicted Conserved microRNA Targets 1.0 0.154935 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the mouth GWASdb SNP-Phenotype Associations 1.0 0.257729 H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00269 hsa-miR-4251 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 CAL-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null REST ENCODE Transcription Factor Targets 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-144 TargetScan Predicted Conserved microRNA Targets 1.0 0.145356 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r5 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12568 OLIG2 ChEA Transcription Factor Targets 1.0 null deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01941 ChIP_JARID2_20075857 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CORL105 CCLE Cell Line Gene CNV Profiles 1.0 1.78106 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01125 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.84154 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34963 CORL47 DepMap CRISPR Gene Dependency 1.0 2.62716 Perturb_13914_KD_SLC45A4_SRP173763 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.21893 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null increased kidney weight MGI Mouse Phenotype Associations 2023 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23547 H3K9ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79846 H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7584-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.45933 NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40836 cystolithiasis MGI Mouse Phenotype Associations 2023 1.0 null H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25739 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14003_OE_Kcna2_SRP309478 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.59395 adrenal gland HPA Tissue Gene Expression Profiles 1.0 1.20034 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00527 hsa-miR-3123 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 EGR1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06023 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27275 phosphate-containing compound metabolic process GO Biological Process Annotations 2023 1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.43394 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.04848 CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.907 hsa-miR-3183 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3523 SRC-2_KO_GDS5087_485_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cervix Carcinoma DisGeNET Gene-Disease Associations 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.774 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71639 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3661 TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25644 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995582 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1836 CCLE Cell Line Gene Expression Profiles -1.0 -2.0838 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25562 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DC-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-671-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.189857 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EGR1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885108 overnutrition GWASdb SNP-Disease Associations 1.0 0.470932 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1981 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4471 layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4307 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45992 hsa-miR-4775 TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARD_KO_GDS4320_619_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-4472 TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12589_KO_Eed_SRP379883 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.08224 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null smooth muscle HPA Tissue Protein Expression Profiles 1.0 0.699006 hsa-miR-548ac TargetScan Predicted Conserved microRNA Targets 1.0 0.436802 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.844809 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0168 hsa-miR-944 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50208 UterusCorpus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.912849 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null intermediate stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74294 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057352 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA(18:1(9Z)/18:1(9Z)) HMDB Metabolites of Enzymes 1.0 null increased circulating chloride level MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAP3K7_knockout_246_GSE34417 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.28735 CAKI2 CCLE Cell Line Gene Expression Profiles 1.0 1.41291 obesity GWASdb SNP-Disease Associations 1.0 0.971169 20211691-TableS1 GeneSigDB Published Gene Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.85185 pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.837517 enlarged heart MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4328 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 tooth disease GWASdb SNP-Disease Associations 1.0 0.382752 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18249 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormal joint morphology GWASdb SNP-Phenotype Associations 1.0 0.179789 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28614 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64497 hsa-miR-563 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.25002 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C99 DepMap CRISPR Gene Dependency 1.0 2.594 abnormal skin morphology MGI Mouse Phenotype Associations 2023 1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10358 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPNYN CCLE Cell Line Gene Expression Profiles 1.0 2.40872 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.958317 PA(18:1(9Z)/18:1(11Z)) HMDB Metabolites of Enzymes 1.0 null regulation of filopodium assembly GO Biological Process Annotations 2023 1.0 null Perturb_15434_KD_KMT9A_SRP154908 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SLR25 CCLE Cell Line Gene Expression Profiles -1.0 -2.13246 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.836571 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null periventricular stratum of TTe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0795 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null vagina HPA Tissue Protein Expression Profiles -1.0 -1.23747 HCC515 DepMap CRISPR Gene Dependency 1.0 2.59939 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.898244 H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.891479 PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.894225 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null phospholipid dephosphorylation GO Biological Process Annotations 2023 1.0 null H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gastrointestinal inflammation GWASdb SNP-Phenotype Associations 1.0 0.254645 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862192 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.845531 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11461 hsa-miR-4727-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 bone disease GWASdb SNP-Disease Associations 1.0 0.130118 hsa-miR-520e TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 AMER1_OE_GDS4802_549_human_HEK293 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Superior colliculus, motor related, deep white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54744 lytic vacuole LOCATE Predicted Protein Localization Annotations 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32795 Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lymph node HPA Tissue Protein Expression Profiles -1.0 -1.23747 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.952005 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PA(20:4(5Z,8Z,11Z,14Z)e/2:0) HMDB Metabolites of Enzymes 1.0 null Perturb_2483_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862504 SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07349 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA(16:0e/18:0) HMDB Metabolites of Enzymes 1.0 null Perturb_8779_Mut_SMARCB1_SRP223162 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.3155 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16281 hsa-miR-3658 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 hsa-miR-28-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16224 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.855279 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null positive regulation of neuron projection development GO Biological Process Annotations 2023 1.0 null H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0233 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57388 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4496 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.189857 MTF2 ChEA Transcription Factor Targets 1.0 null NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.913519 H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null PA(P-16:0e/18:2(9Z,12Z)) HMDB Metabolites of Enzymes 1.0 null hsa-miR-4768-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 RH30 CCLE Cell Line Gene CNV Profiles 1.0 1.91075 CAL33 CCLE Cell Line Gene Expression Profiles -1.0 -1.88027 r9 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20245 hsa-miR-3127-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the teeth GWASdb SNP-Phenotype Associations 1.0 0.223565 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042486 ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H2085 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null D283MED DepMap CRISPR Gene Dependency 1.0 3.95394 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-151-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.71667 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39767 hsa-miR-590-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.159923 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995582 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051263 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fusiform gyrus, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04233 Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10358 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911906 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LEDGF_KD_GDS1580_249_human_293T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-302d TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 OUMS-23 COSMIC Cell Line Gene Mutation Profiles 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1981 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58137 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8195-01A-31R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of SeStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1839 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5200-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11797 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_02_26 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.08746 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.950779 NCI-H2135 COSMIC Cell Line Gene CNV Profiles 1.0 2.49065 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15129 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3127-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 JARID2-20064375-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -1.61987 H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0345 SNU620 CCLE Cell Line Gene Expression Profiles -1.0 -1.46426 hsa-miR-4672 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TC71 DepMap CRISPR Gene Dependency 1.0 2.34454 tooth disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 CJM DepMap CRISPR Gene Dependency 1.0 4.23601 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19212 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null enlarged lymph nodes MGI Mouse Phenotype Associations 2023 1.0 null hsa-miR-302e TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27259 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.97858 Perturb_4867_KO_HES1/NEUROG3_ERP110708 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.07688 hsa-miR-3679-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.127531 placenta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.235167 CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.59759 inflammation of the large intestine GWASdb SNP-Phenotype Associations 1.0 0.350059 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862504 hsa-miR-513b TargetScan Predicted Conserved microRNA Targets 1.0 0.226173 TT CCLE Cell Line Gene CNV Profiles -1.0 -1.35774 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-151b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SKNFI CCLE Cell Line Gene Expression Profiles 1.0 1.51348 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1981 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041123 NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15532 hsa-miR-4659b-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r8 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60538 WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71831 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862504 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null External cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33055 nervous system disease GWASdb SNP-Disease Associations 1.0 0.088495 Ankylosing Spondylitides_macrophage_GSE11886 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.42064 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VMRCRCW DepMap CRISPR Gene Dependency 1.0 2.38919 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3949 hsa-miR-3145-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.136254 H3K27me3_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4753-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.56299 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.39472 TCF4 ChEA Transcription Factor Targets 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.96762 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.171384 mania GWASdb SNP-Phenotype Associations 1.0 0.452152 PCI4B DepMap CRISPR Gene Dependency 1.0 3.51289 Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13371 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6902 ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.008193 increased grooming behavior MGI Mouse Phenotype Associations 2023 1.0 null WM115 CCLE Cell Line Gene CNV Profiles -1.0 -1.81978 Interanterodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69448 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42126 COLO679 DepMap CRISPR Gene Dependency 1.0 2.39818 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27718 HCC1187 CCLE Cell Line Gene CNV Profiles -1.0 -2.19982 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.873096 CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.098351 SKNSH CCLE Cell Line Gene Expression Profiles 1.0 1.51349 H3K4me1_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsal peduncular cortex, periventricular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08066 HCC1954 DepMap CRISPR Gene Dependency 1.0 2.72891 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00236 Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.829662 Perturb_2493_Mut_ESR1_SRP254635 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GB1 CCLE Cell Line Gene Expression Profiles -1.0 -2.34732 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55224 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.994464 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.185591 Kidney renal clear cell carcinoma_KIRC_TCGA-MW-A4EC-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08066 NCIH1838 CCLE Cell Line Gene CNV Profiles 1.0 1.45601 abnormality of taste sensation GWASdb SNP-Phenotype Associations 1.0 0.563675 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04249 Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07159 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.116204 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89668 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-29a TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38923 ovary HPA Tissue Protein Expression Profiles -1.0 -1.23747 nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ChIP_RNF2_22325148 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27275 sensory system disease GWASdb SNP-Disease Associations 1.0 0.660239 SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42423 ZNF143 ENCODE Transcription Factor Targets 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-2113 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05299 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-544b TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36753 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.976024 anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.899333 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nasopharynx HPA Tissue Protein Expression Profiles 1.0 0.699006 REST ChEA Transcription Factor Targets 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.006 MAX ENCODE Transcription Factor Targets 1.0 null RCC10RGB DepMap CRISPR Gene Dependency 1.0 2.46242 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74083 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51033 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fog2_KO_GDS3659_152_mouse_adult heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 786O DepMap CRISPR Gene Dependency 1.0 2.39507 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.913519 KMRC2 CCLE Cell Line Gene Expression Profiles 1.0 1.71342 MAFK ENCODE Transcription Factor Targets 1.0 null hsa-miR-3918 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Sarcoma_SARC_TCGA-QQ-A8VF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormality of body height GWASdb SNP-Phenotype Associations 1.0 0.497391 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59712 IMR32 DepMap CRISPR Gene Dependency 1.0 4.1066 COLO704 CCLE Cell Line Gene Expression Profiles 1.0 2.65491 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1332 increased body weight MGI Mouse Phenotype Associations 2023 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245807 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of skeletal morphology GWASdb SNP-Phenotype Associations 1.0 0.058895 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null abnormality of body weight GWASdb SNP-Phenotype Associations 1.0 0.357225 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.926601 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.4785 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13371 hydrolase activity GO Molecular Function Annotations 2015 1.0 null dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.999031 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14376 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.47826 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.99375 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29526 H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38914 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 decreased locomotor activity MGI Mouse Phenotype Associations 2023 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Main olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77726 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25098 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 253J CCLE Cell Line Gene Expression Profiles 1.0 1.86312 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OB outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6915 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.888033 CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.70696 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052303 Superior colliculus, motor related, intermediate white layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04864 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60322 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A4EM-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04574 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23363 MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.01522 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.995582 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07437 AKT2_knockdown_44_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.97823 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03958 KYAE1 DepMap CRISPR Gene Dependency 1.0 2.54605 hsa-miR-4719 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null sensory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.63207 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.53006 posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.941721 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL148 CCLE Cell Line Gene Expression Profiles -1.0 -1.69696 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4217-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.553683 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10682 RCOR1 ENCODE Transcription Factor Targets 1.0 null obesity GWASdb SNP-Phenotype Associations 1.0 0.855449 H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null SNU398 DepMap CRISPR Gene Dependency 1.0 8.26686 H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1569 COSMIC Cell Line Gene Mutation Profiles 1.0 null JL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60576