association dataset threshold value standardized value lymphoma GWASdb SNP-Phenotype Associations 1.0 0.45416 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -0.931231 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.412 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7005 asthma GWASdb SNP-Disease Associations 1.0 0.532414 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100491_HIP_no dementia_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28827 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE127790_5_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ERCC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07603 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.38793 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NPAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14525 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11753 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.8668 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7373 DNAJB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53333 GSE60837_0_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XUZC-1426-SM-4BRV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992306 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861941 short sperm flagellum MGI Mouse Phenotype Associations 2023 1.0 null HSC3 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.25781 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR4 CCLE Cell Line Gene Expression Profiles -1.0 -1.53356 GSE200982_0_v_2_plac8_human RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.86136 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7545 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949211 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.862 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.532414 GATA2 ChEA Transcription Factor Targets 1.0 null abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.161333 Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.801 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH322 CCLE Cell Line Gene CNV Profiles -1.0 -1.8476 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02025 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null Trachea-ionocyte Tabula Sapiens Gene-Cell Associations 1.0 -0.0850252 HUT78 CCLE Cell Line Gene Mutation Profiles 1.0 null primary auditory cortex (core)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25622 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.038982 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845676 gamma-tubulin small complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.587 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.80111 GSE248770_0_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 OVTOKO DepMap CRISPR Gene Dependency 1.0 4.3025 primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28288 HDAC2 ENCODE Transcription Factor Targets 1.0 null PRKCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20319 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31648 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral medial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986308 ITGA7_OE_GDS3209_142_mouse_skeletal muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.16916 SREBF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11963 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4821 posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.66704 GSE130401_4_v_3_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_4566_KD_Setdb1_SRP172038 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.15086 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.69237 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16422 organ system cancer GWASdb SNP-Disease Associations 1.0 0.111172 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.923877 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.13316 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE180951_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3891 PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3 Rummagene Transcription Factor Associations 2026 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -1.17774 GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.962451 FUS-26573619-CHIP-SEQ-HEK293-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MA-104 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.544 GSE183251_1_v_0_cyp2c70_mouse RummaGEO Gene Perturbation Signatures 1.0 null FBRSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75638 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06149 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14556 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7509 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null chr7_134063556_A_G_b38 GTEx eQTL 2025 1.0 1.0465 Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.89372 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null SKMEL3 CCLE Cell Line Gene Expression Profiles 1.0 1.49886 SIX5 ENCODE Transcription Factor Targets 1.0 null GTEX-XOTO-2826-SM-4B65I GTEx Tissue Sample Gene Expression Profiles 1.0 0.910121 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9636 Familial cold autoinflammatory syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.315 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100490_HIP_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03699 HCFC1 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null asthenozoospermia MGI Mouse Phenotype Associations 2023 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.57735 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LY2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.03675 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.954504 NR2C2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POMQ-0126-SM-48TD6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.87602 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TXNL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00988 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.9784 Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.096 EIF5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21474 GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null YY1_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null Hedgehog signaling complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.544 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9113 GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.973033 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.87039 Phosphoglycerate kinase 1 deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.287 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2748 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YKG1 DepMap CRISPR Gene Dependency 1.0 2.65378 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.20735 JUN ChEA Transcription Factor Targets 1.0 null K029AX CCLE Cell Line Gene Expression Profiles 1.0 1.63425 NR2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14485 GSE76425_0_v_10_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.970605 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.081039 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94144 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ventrolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.982364 H3K27ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null QGP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.93362 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE152699,GSE152723_0_v_1_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null Left_Ventricle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.20328 NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YO-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.991264 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1653 catalytic activity GO Molecular Function Annotations 2015 1.0 null Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.1885 spontaneous chromosome breakage MGI Mouse Phenotype Associations 2023 1.0 null ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.043 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835118 8MGBA CCLE Cell Line Gene Expression Profiles -1.0 -1.45585 SW620 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE152699,GSE152723_3_v_1_vemurafenib_human RummaGEO Drug Perturbation Signatures 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910981 MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE167956_1_v_0_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OXRP-0226-SM-3NB14 GTEx Tissue Sample Gene Expression Profiles 1.0 0.861166 TAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01738 FASTKD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08515 GTEX-UPK5-1626-SM-4JBHI GTEx Tissue Sample Gene Expression Profiles 1.0 0.936096 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35236 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VMRCRCZ CCLE Cell Line Gene Mutation Profiles 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.851 cellular process GO Biological Process Annotations 2015 1.0 null PRDM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.9362 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Centriole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.189 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05258 GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 496100372_HIP_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.48282 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04296 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM14-21183938-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-1826-SM-3GIL1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.838579 Perturb_13194_KO_Dax1_ERP127280 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.99573 SNU349 CCLE Cell Line Gene Mutation Profiles 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.28628 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00967 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51113 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53473 lymphopenia GWASdb SNP-Disease Associations 1.0 0.532414 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RBL1_KO_GDS1932_739_mouse_Neurospheres GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-S32W-2026-SM-4AD6E GTEx Tissue Sample Gene Expression Profiles 1.0 0.869661 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5535 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42247 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7444072__F5 PFOCR Pathway Figure Associations 2023 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00404 POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV31-0008-SM-447AT GTEx Tissue Sample Gene Expression Profiles 1.0 0.902367 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TFAP2C-20629094-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CHL1 CCLE Cell Line Gene Mutation Profiles 1.0 null medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3761 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE145628,GSE145629_1_v_0_myrf_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE205976,GSE205978_3_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null GSE123861_1_v_0_sin3a_human RummaGEO Gene Perturbation Signatures 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.883969 GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951375 GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84473 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cancer GWASdb SNP-Disease Associations 1.0 0.102908 GTEX-WFG8-0426-SM-3GILD GTEx Tissue Sample Gene Expression Profiles 1.0 0.878988 PMC12673788-12967_2025_7484_MOESM5_ESM.xlsx-Venne_panel-Only_OCT4_related_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03618 SNU626 CCLE Cell Line Gene CNV Profiles 1.0 1.57866 vp8 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.701 H3K9ac_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.880038 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.886394 ONDA9 DepMap CRISPR Gene Dependency 1.0 2.10051 GSE150134_1_v_0_scn5a_human RummaGEO Gene Perturbation Signatures -1.0 null HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.5537 Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.04662 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44749 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.87471 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 2.05526 Phosphopyruvate hydratase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.104 GTEX-S95S-0826-SM-4B64N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841666 DEOC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05955 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UACC62 CCLE Cell Line Gene Expression Profiles 1.0 2.04528 H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14735 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00214 cytoplasm GO Cellular Component Annotations 2015 1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleoside monophosphate kinase activity GO Molecular Function Annotations 2025 1.0 null GSE94011_0_v_3_pias3_mouse RummaGEO Gene Perturbation Signatures -1.0 null TC-71 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.917504 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.884692 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16174 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3997 GSE171837_0_v_3_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.94804 Prostate adenocarcinoma_PRAD_TCGA-HC-A631-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S3XE-0426-SM-3K2AC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903072 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.973064 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 4.49255 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.027 SET2 CCLE Cell Line Gene CNV Profiles -1.0 -1.34746 GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88382 purine nucleoside binding GO Molecular Function Annotations 2015 1.0 null GTEX-QESD-1726-SM-2S1R7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male infertility due to acephalic spermatozoa DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.176 H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amyotrophic lateral sclerosis GWASdb SNP-Disease Associations 1.0 0.520031 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Guanylate kinase-like InterPro Predicted Protein Domain Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00236 YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null JHOM2B CCLE Cell Line Gene CNV Profiles -1.0 -1.4531 E2F4 ENCODE Transcription Factor Targets 1.0 null HOS CCLE Cell Line Gene CNV Profiles -1.0 -1.4664 GTF2F1 ENCODE Transcription Factor Targets 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11209 Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum pyramidale of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.857518 RPS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23501 POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null smallintestine_4d HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 GTEX-P4PP-0926-SM-48TBZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.897512 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BBSome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.234 BL4184 (USP16) NURSA Protein Complexes 1.0 null phosphorylation GO Biological Process Annotations 2015 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62904 Number of sexual partners GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.02218 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3626 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.0086 HOP92 CCLE Cell Line Gene CNV Profiles 1.0 1.51324 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null GSE134375_0_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null LUDLU1 CCLE Cell Line Gene Mutation Profiles 1.0 null GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 12.97 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9448 VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.17538 Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100389_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23581 H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.904128 MDAMB361 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE159893_2_v_0_genistein_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.3352 GSE109530,GSE109531_1_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8617 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 axoneme assembly GO Biological Process Annotations 2025 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14753 GTEX-WH7G-0526-SM-3NMBI GTEx Tissue Sample Gene Expression Profiles 1.0 1.04014 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6426 acrosomal vesicle GO Cellular Component Annotations 2023 1.0 null leukocyte disease GWASdb SNP-Disease Associations 1.0 0.280088 FOXH1-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KYSE270 CCLE Cell Line Gene Expression Profiles -1.0 -1.90416 acute lymphatic leukemia GWASdb SNP-Phenotype Associations 1.0 0.594504 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.18858 H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MH-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH2023 CCLE Cell Line Gene Mutation Profiles 1.0 null Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.096 leukemia GWASdb SNP-Phenotype Associations 1.0 0.25984 Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913599 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20938 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.747066 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CREM ChEA Transcription Factor Targets 1.0 null H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.857614 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00437 Perturb_4514_KD_Tip60_SRP081300 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.92217 GTEX-OXRN-0226-SM-2I5EJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.951946 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8943 Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32186 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE223609,GSE223610_0_v_1_kdm6a_human RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.28628 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7385 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5DU-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE203329_0_v_3_mettl5_human RummaGEO Gene Perturbation Signatures -1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.945087 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835115 MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7857 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0826-SM-2XCBF GTEx Tissue Sample Gene Expression Profiles 1.0 1.10045 GTEX-RWSA-2026-SM-47JX8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36768 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.072727 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19161 microtubule bundle formation GO Biological Process Annotations 2025 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.990152 EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-1326-SM-3NM8X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2535 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152441,GSE152442_0_v_2_folic acid_human RummaGEO Drug Perturbation Signatures 1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6359 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.02992 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0468 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.878846 GTEX-TKQ1-1326-SM-4DXU7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905957 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 2.285 GATA2-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE137914_0_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.071 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.63658 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE131161_1_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10675 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.880516 primary motor cortex (area M1, area 4)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01879 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.974211 GTEX-VJYA-0826-SM-4KL1M GTEx Tissue Sample Gene Expression Profiles 1.0 0.848923 NCI-H2347 COSMIC Cell Line Gene Mutation Profiles 1.0 null SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 0.04545 Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26872 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0491 COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54163 GTEX-UJHI-0426-SM-3DB8Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10324 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.10896 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16554 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.4676 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3158 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.00996 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91026 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32112 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.98391 disease GWASdb SNP-Disease Associations 1.0 0.044541 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.833234 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE235587_2_v_1_mitoxantrone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-RWSA-0626-SM-2XCBD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null GTEX-SE5C-0626-SM-2XCDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.872528 phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null Vero cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.199 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829509 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.59446 H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE169356_2_v_3_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE220914_1_v_0_zdhhc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null VMAC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55722 GTEX-Q2AG-0926-SM-48U1Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.999674 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4859 nucleoplasm GO Cellular Component Annotations 2015 1.0 null CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.906159 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.23466 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE131161_5_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.868671 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null SNU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.929025 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24658 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 2.15346 GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829938 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01406 GSE126402_4_v_7_tal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QDT8-0926-SM-32PL2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.920363 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.859011 GSE214505_0_v_1_akr1b1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr7_134155899_T_C_b38 GTEx eQTL 2025 1.0 2.08945 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.827622 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVK18 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 leukemia GWASdb SNP-Disease Associations 1.0 0.532414 Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.86044 GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860908 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NFK9-0726-SM-2HMJW GTEx Tissue Sample Gene Expression Profiles 1.0 0.903185 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.45518 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1161 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.845738 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HGC-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8537 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.186006 AGAP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57787 Perturb_4530_KD_Sae1_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.69187 GTEX-SNMC-0926-SM-4DM5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.26602 YY1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary ciliary dyskinesia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.783 Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.796 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34051 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.38984 GTEX-R55E-0126-SM-2TC5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.08455 H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE81803,GSE81912_3_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6341 COLO679 CCLE Cell Line Gene CNV Profiles 1.0 1.67632 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.915902 PMC11073972-41375_2024_2232_MOESM2_ESM.xlsx-REL-14_CD7_CD1a-_L-IC_DEG-DEG_L2FC_1_0_FDR_0_05_REL Rummagene Transcription Factor Associations 2026 1.0 null appendices_4c HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130864_0_v_1_tincr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UPK5-0326-SM-3GAF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ATP5F1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39937 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.615 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0442 GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07319 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09676 FBXW2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04055 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.562 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFKB1_01_167 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62167 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ZNF384 ENCODE Transcription Factor Targets 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MCF7_PF-3845_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.014583 ZDHHC22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65323 Body Mass Index Procedure DisGeNET Gene-Phenotype Associations 1.0 null heart_5b HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224969,GSE224971_3_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.2066 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00637 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00777 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE116354,GSE117379_3_v_5_cox2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-711 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.39945 inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.917342 LS411N CCLE Cell Line Gene Mutation Profiles 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17368 YY1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.09746 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LOVO COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 496100445_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06067 posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.832442 H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Guanylate kinase/L-type calcium channel beta subunit InterPro Predicted Protein Domain Annotations 1.0 null Small_Intestine Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.5967 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HD-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 GSE174498,GSE174500_3_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE176008_8_v_1_azacitidine_human RummaGEO Drug Perturbation Signatures -1.0 null chr7_134058640_A_G_b38 GTEx eQTL 2025 1.0 1.09925 GTEX-XQ8I-1826-SM-4BOOJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18608 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7583 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null NRF1 ENCODE Transcription Factor Targets 1.0 null TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.969641 HEC251 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-XUZC-0008-SM-4BOQG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961858 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0208 GTEX-QDVN-0626-SM-2I3FP GTEx Tissue Sample Gene Expression Profiles 1.0 0.913263 blood pressure GAD Gene-Disease Associations 1.0 null GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWOO-1526-SM-48TCK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856375 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2966 AN3CA CCLE Cell Line Gene Mutation Profiles 1.0 null GSE210101,GSE210114_5_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null p-selectin GAD Gene-Disease Associations 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936447 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15908 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GM-06B-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904365 Perturb_5273_KO_Rif1_SRP348198 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.31054 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.532 MXI1 ENCODE Transcription Factor Targets 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03693 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1145 GSE195513_0_v_3_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13627 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_15770_KO_Uxt_SRP240277 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 NFYB_02_24 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59946 GSE142210_9_v_6_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.906723 GRHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08957 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.848688 GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE109530,GSE109531_2_v_0_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null diabetes, type 2 GAD Gene-Disease Associations 1.0 null MALME3M CCLE Cell Line Gene CNV Profiles 1.0 1.62906 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3675 L428 CCLE Cell Line Gene Mutation Profiles 1.0 null testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.28093 HOP-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28793 Testicular vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.845 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.848153 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3468-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPK-1826-SM-2YUMR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13947 OV-90 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9708 atp binding GO Molecular Function Annotations 2015 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.14513 GSE87412,GSE92423_2_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perisynaptic extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.857 TCF7L2 ENCODE Transcription Factor Targets 1.0 null GSE242555_1_v_0_fn3k_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60897 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16666 X-linked lymphoproliferative syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.156 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22373 H3K4me1_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJWN-0726-SM-3GIJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.824936 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.37374 intestine-407 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.651 CNPY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42252 GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3069 EP400 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66528 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.915521 GTEX-UJHI-1426-SM-3DB9C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Annuli extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.798 Acute Myeloid Leukemia_LAML_TCGA-AB-2875-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53363 GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null MALME3M CCLE Cell Line Gene Expression Profiles 1.0 2.65689 NZOV9 DepMap CRISPR Gene Dependency 1.0 4.76981 ETS1 ENCODE Transcription Factor Targets 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.850504 Exocyst COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.26 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180200,GSE180201_15_v_11_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE254517_2_v_0_irf7_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.09192 OTOL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1152 MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.09358 GTEX-S4Q7-0008-SM-3NM8A GTEx Tissue Sample Gene Expression Profiles 1.0 0.9907 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.4758 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.02941 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.46585 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843495 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66934 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05031 A101D COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.984332 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE84148,GSE96938_3_v_1_nrros_mouse RummaGEO Gene Perturbation Signatures -1.0 null SPATA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73287 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TMEM94 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07198 H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormal spermiation MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8315 H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8370976-41467_2021_24932_MOESM7_ESM.xlsx-Annotation-Supplementary_Data_5_GO_and_metascape_analysis_of_the_genes_upregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FTC-133 COSMIC Cell Line Gene Mutation Profiles 1.0 null transferase activity GO Molecular Function Annotations 2015 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.100503 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4LF-0426-SM-3NMB5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01411 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.906284 SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-4716-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25595 H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.14328 H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE109530,GSE109531_2_v_3_hdac3_mouse RummaGEO Gene Perturbation Signatures -1.0 null TUHR14TKB DepMap CRISPR Gene Dependency 1.0 3.24299 GTEX-OXRL-2626-SM-2I3F1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884302 PEO4 DepMap CRISPR Gene Dependency 1.0 3.40266 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6 LN18 CCLE Cell Line Gene Expression Profiles -1.0 -1.53822 GTEX-OIZH-0326-SM-2HMKC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922875 Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26914 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PITX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07247 posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14832 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877671 intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91224 STAT3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55471 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.31175 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles 1.0 1.3543 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2433 oligozoospermia MGI Mouse Phenotype Associations 2023 1.0 null 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5554 NCIH1339 CCLE Cell Line Gene CNV Profiles -1.0 -1.39723 GTEX-R55C-0326-SM-3GAF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21028 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null small molecule binding GO Molecular Function Annotations 2015 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20196 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.947557 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 58.0186 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null bronchial disease GWASdb SNP-Disease Associations 1.0 0.532414 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.28484 IGR37 CCLE Cell Line Gene Expression Profiles 1.0 1.55116 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SIN3A_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE186440,GSE186443_4_v_5_daxx_human RummaGEO Gene Perturbation Signatures 1.0 null testis HPA Tissue Protein Expression Profiles 1.0 0.859011 biological_process GO Biological Process Annotations 2015 1.0 null PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Up_REST Rummagene Transcription Factor Associations 2026 1.0 null Finding Of Body Mass Index DisGeNET Gene-Phenotype Associations 1.0 null THOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49087 amyotrophic lateral sclerosis GWASdb SNP-Phenotype Associations 1.0 0.443596 AR-19668381-PC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TC32 CCLE Cell Line Gene CNV Profiles -1.0 -2.22559 GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02618 CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFE2L2_02_174 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.848 Microtubule cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE127790_11_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.953011 NUPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65436 GTEX-WH7G-1726-SM-4LVKY GTEx Tissue Sample Gene Expression Profiles 1.0 1.42002 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.03 GTEX-P4PQ-1526-SM-3NMCK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-XOT4-0726-SM-4GIAW GTEx Tissue Sample Gene Expression Profiles 1.0 0.968745 GSE242555_1_v_0_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28015 MAX ENCODE Transcription Factor Targets 1.0 null SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17067 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18066 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.59 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5376 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.37158 GSE137914_4_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-548am TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 L3MBTL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13319 primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.837482 NCIH2087 CCLE Cell Line Gene Expression Profiles -1.0 -2.71387 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896295 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3664 GSE200673,GSE200691_1_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4533 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53751 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1765 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.02449 WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05657 Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5525 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17663 Macronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.11 GSE148695,GSE167281_0_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POYW-0008-SM-48TE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.12586 SPDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27448 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIX5_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 42.8933 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO849 CCLE Cell Line Gene CNV Profiles 1.0 2.31418 PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.874217 GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-P4PQ-0326-SM-2HMJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24179 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24076 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04652 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.84091 COLO792 CCLE Cell Line Gene Expression Profiles 1.0 2.40858 ZNF384_02_27 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.08746 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TFAP2C-20629094-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE155695,GSE155696_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.86953 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3055 SIX5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881691 Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hel HPA Cell Line Gene Expression Profiles -1.0 -1.05471 GABARAPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81788 cdx2_20696899_caco2_lof_human_gpl570_gse22572 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.088451 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null leukopenia GWASdb SNP-Disease Associations 1.0 0.333007 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1057 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 cellular component assembly GO Biological Process Annotations 2023 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99765 Inner acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.131 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910981 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT55 DepMap CRISPR Gene Dependency 1.0 2.73782 Sperm midpiece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.651 AUTS2-25519132-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.22152 Developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.543 PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC Rummagene Transcription Factor Associations 2026 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.39837 Collagen and cuticulin-based cuticle extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.797 HO-1-N-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PW2O-0426-SM-48TCC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894191 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.995608 GTEX-QEG4-1226-SM-2S1P6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE75976_3_v_6_abl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5838 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE235945_1_v_0_pikfyve_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.6857 guanylate kinase activity GO Molecular Function Annotations 2025 1.0 null GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35143 COV434 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.872713 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SW1271 CCLE Cell Line Gene Mutation Profiles 1.0 null PRDM14-21183938-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GSE202434,GSE202438_10_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 kinase activity GO Molecular Function Annotations 2015 1.0 null telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910274 Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.096 anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.862233 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78756 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.67305 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYVS-0526-SM-3NM9W GTEx Tissue Sample Gene Expression Profiles 1.0 1.21979 GTEX-WQUQ-1426-SM-3MJFD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928432 VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1116 ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.898353 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26035 FARAGE DepMap CRISPR Gene Dependency 1.0 2.5146 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5504 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934024 Pervasive developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.867 NR2C2 ENCODE Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.16996 Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cellular_component GO Cellular Component Annotations 2015 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -0.881524 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05461 GSE181959_3_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null 9+0 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.173 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5549 GPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01473 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 hsa-miR-657 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Perturb_4531_KD_Senp6_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.50135 GSE126402_4_v_6_tal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84065 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA7_HOXA7 Rummagene Transcription Factor Associations 2026 1.0 null anion binding GO Molecular Function Annotations 2015 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06554 GATA2 ENCODE Transcription Factor Targets 1.0 null GTEX-R55E-1026-SM-2TC5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881058 H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KIF18B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32094 INTS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87649 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.96883 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14591 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.33483 fallopian tube HPA Tissue Protein Expression Profiles 1.0 0.859011 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835793 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18369 forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.78795 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE57397,GSE57399_1_v_0_fbxw7_human RummaGEO Gene Perturbation Signatures 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07244 SIN3A_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL2 CCLE Cell Line Gene Expression Profiles 1.0 2.25138 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.40987 GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRCA1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100671_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08702 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.974156 REM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14913 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5357 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH2 CCLE Cell Line Gene CNV Profiles 1.0 1.5641 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AC16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19621 GTEX-P78B-0008-SM-48TE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00962 inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09528 upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.836428 GSE209698_2_v_1_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.50767 H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MDA-MB-361 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 SYO1 DepMap CRISPR Gene Dependency 1.0 3.41498 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972105 GTEX-OXRL-1626-SM-2YUMU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04242 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.62313 Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null P31-FUJ COSMIC Cell Line Gene Mutation Profiles 1.0 null CL11 CCLE Cell Line Gene CNV Profiles 1.0 1.49357 HT115 CCLE Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4526_KO_Chaf1b_ERP006640 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.20653 Perturb_16573_KO_Grn_SRP070944 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.31695 Radial spoke head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.358 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11753 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51092 GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946922 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.833904 IPC298 CCLE Cell Line Gene Expression Profiles 1.0 1.39223 Axonemal central pair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.159 cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ING3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08437 Acid phosphatase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.708 GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-T5JC-0326-SM-4DM5C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01387 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997922 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4725 GSE246184,GSE246195_0_v_1_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07685 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.113 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE149123,GSE149128_1_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2696 TE9 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 LS180 CCLE Cell Line Gene Mutation Profiles 1.0 null VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2048 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.65052 detached acrosome MGI Mouse Phenotype Associations 2023 1.0 null Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.033 GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.49849 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17796 EB-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946922 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.5281 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.47909 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20078 primary motor-sensory cortex (samples)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.872106 GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUZ12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57017 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.068314 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-0326-SM-33HC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.864596 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19382 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5884 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00503 CCK81 DepMap CRISPR Gene Dependency 1.0 8.58815 GSE223540_0_v_3_anxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868024 primary motor cortex (area M1, area 4)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.991974 H3K4me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SW1116 CCLE Cell Line Gene Expression Profiles -1.0 -1.52491 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02129 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1399 TTI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23491 CTBP1-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YY1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SSA3-0008-SM-47JWJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15066 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5WG-2426-SM-4LMI6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830056 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-0926-SM-4IHKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03434 GTEX-RN64-0126-SM-2TC68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.992275 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOGGUVW DepMap CRISPR Gene Dependency 1.0 7.0339 Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.595 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05025 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946922 LU-135 COSMIC Cell Line Gene Mutation Profiles 1.0 null purine nucleotide binding GO Molecular Function Annotations 2015 1.0 null PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC7806950-mmc2.xlsx-KRAB_Significant-DEGs-Table_S2_Significant_DEGs_following_targeting_of_dSaCas9-repressors_to_DUX4_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.903907 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 1.04415 parathyroid gland HPA Tissue Protein Expression Profiles 1.0 0.859011 GSE169263_1_v_0_armc5_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1143 CCLE Cell Line Gene CNV Profiles -1.0 -1.33052 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149355_0_v_1_esrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-VUSG-0526-SM-4KL22 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04163 cerebellar cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.899834 GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.067 Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28793 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.76579 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU1J-0226-SM-2TF5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.04993 SIX5_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE117045_1_v_2_amphetamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null atrophy/degeneration affecting the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.443596 organelle LOCATE Predicted Protein Localization Annotations 1.0 null WM983B CCLE Cell Line Gene CNV Profiles 1.0 1.65271 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.976425 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.47909 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CW9019 DepMap CRISPR Gene Dependency 1.0 3.56368 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IL17C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13817 primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3286 nucleotide binding GO Molecular Function Annotations 2015 1.0 null GSE213588_9_v_4_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32391 Microtubule end COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.008 Ependymal cell_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE205976,GSE205978_1_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null Specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.543 mediodorsal nucleus of thalamus_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37961 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9807 SREBF1 ENCODE Transcription Factor Targets 1.0 null CDKN2AIPNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31835 abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.061392 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6585 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WK11-0626-SM-3NMAV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 SMARCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11541 Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.229 H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null HCC1395 DepMap CRISPR Gene Dependency 1.0 3.09809 ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null heart_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.06662 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.98093 Loin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.332 ZXDB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14478 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02025 AR-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null nucleoside phosphate binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 2.285 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 obstructive lung disease GWASdb SNP-Disease Associations 1.0 0.333007 GSE229914_1_v_3_keap1_human RummaGEO Gene Perturbation Signatures 1.0 null HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64886 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUHR4TKB CCLE Cell Line Gene Mutation Profiles 1.0 null GSE210101,GSE210114_4_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.933768 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GR MotifMap Predicted Transcription Factor Targets 1.0 null SNUC5 CCLE Cell Line Gene Mutation Profiles 1.0 null purine ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196104,GSE196106_3_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.847974 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null GSE226091,GSE226092_3_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures 1.0 null outer SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929524 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 46.2277 Autism spectrum disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.867 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997239 axoneme assembly GO Biological Process Annotations 2023 1.0 null H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52171 skmel30 HPA Cell Line Gene Expression Profiles 1.0 1.36011 MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SREBP-SCAP-Insig complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.061 SNU-C1 COSMIC Cell Line Gene Mutation Profiles 1.0 null D-423MG COSMIC Cell Line Gene Mutation Profiles 1.0 null DAUDI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.969118 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FL-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE180200,GSE180201_3_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.841817 GSE171837_3_v_1_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null abnormal acrosome morphology MGI Mouse Phenotype Associations 2023 1.0 null YIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25423 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2416 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1053 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-0426-SM-4B64I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HPBALL CCLE Cell Line Gene Expression Profiles 1.0 1.40702 H3K4me1_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null adenyl ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null Cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 2.285 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE217541,GSE217543_0_v_1_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23766 Trachea-ciliated cell Tabula Sapiens Gene-Cell Associations 1.0 6.80362 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40634 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null GTEX-SE5C-0726-SM-4BRWY GTEx Tissue Sample Gene Expression Profiles 1.0 1.02796 GTEX-XYKS-0226-SM-4BRW3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.838811 GSE130081,GSE130082_4_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964181 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10746 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997239 TEAD4-22529382-TROPHECTODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HUNS1 CCLE Cell Line Gene CNV Profiles -1.0 -1.5993 PMC7444072__F5 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-PWN1-2626-SM-2I3FH GTEx Tissue Sample Gene Expression Profiles 1.0 1.05279 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE185163_3_v_1_clic4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.01498 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03972 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AR-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cumulus-oocyte complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.94 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840064 NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937152 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158320,GSE183351_2_v_3_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null acute lymphocytic leukemia GWASdb SNP-Disease Associations 1.0 0.692909 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.72928 Perturb_4533_KD_Uba2_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.53014 Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.116 prostate HPA Tissue Protein Expression Profiles 1.0 0.859011 hESC Derived CD184+ Endoderm Cultured Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.02368 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06275 PL18 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11408518-41598_2024_73146_MOESM5_ESM.xlsx-Intersection_gene-NCOA1_NCOA1 Rummagene Transcription Factor Associations 2026 1.0 null C32 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08419 hsa-miR-3064-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null L-540 COSMIC Cell Line Gene Mutation Profiles 1.0 null A101D CCLE Cell Line Gene CNV Profiles 1.0 2.49924 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.25989 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null C32 CCLE Cell Line Gene Expression Profiles 1.0 1.83874 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.906 HEP_3B2_1-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 0.975826 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880394 head and face region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31092 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14739 GTEX-WYVS-2126-SM-3NMA3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.996732 ZNF263 ENCODE Transcription Factor Targets 1.0 null GSE60837_6_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.953011 abnormality of lymphocytes GWASdb SNP-Phenotype Associations 1.0 0.45416 IM95 DepMap CRISPR Gene Dependency 1.0 7.01384 GTEX-U3ZH-0426-SM-4DXSE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0388 Tassel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.521 NCI-H2087 COSMIC Cell Line Gene Mutation Profiles 1.0 null Diabetes Mellitus DisGeNET Gene-Disease Associations 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32598 GFI1B ChEA Transcription Factor Targets 1.0 null PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF Rummagene Transcription Factor Associations 2026 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.229032 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.897731 GTEX-T2IS-0426-SM-32QPE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null CHD1_02_187 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.58496 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.040309 HCT116 CCLE Cell Line Gene CNV Profiles -1.0 -2.31251 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15763 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.39837 GSE118794_5_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8758 DDX31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70418 dorsolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.40987 GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles 1.0 0.962847 organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.92222 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.55074 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914819 H3K9ac_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877759 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HT1197 DepMap CRISPR Gene Dependency 1.0 2.42564 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 0.999743 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 Microtubule plus-end COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.97 YY1-26981420-C2C12-MOUSE-MUSCLE ChEA Transcription Factor Targets 2022 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88459 KHNYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01572 Outer dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.199 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950836 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910274 GTEX-SN8G-0001-SM-3NM8L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14906 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.9141 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE169205_0_v_1_sirt5_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH2347 CCLE Cell Line Gene Mutation Profiles 1.0 null NCIH2126 CCLE Cell Line Gene CNV Profiles 1.0 1.86174 496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08367 HEY DepMap CRISPR Gene Dependency 1.0 3.65296 amygdaloid complex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.895864 SIX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-2826-SM-46MWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 HS737T CCLE Cell Line Gene Expression Profiles -1.0 -2.32116 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.21955 acrosomal vesicle GO Cellular Component Annotations 2025 1.0 null H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-0526-SM-48TZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06782 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acrosomal vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MELHO CCLE Cell Line Gene Expression Profiles 1.0 3.36261 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.99542 NCIH520 CCLE Cell Line Gene Expression Profiles -1.0 -1.77802 DBTRG05MG CCLE Cell Line Gene Mutation Profiles 1.0 null CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6431 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Perturb_16102_KO_Map3k12_SRP157873 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P78B-0426-SM-2I5F5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08349 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2003 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03674 RHBDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04445 MDAMB361 CCLE Cell Line Gene Expression Profiles -1.0 -2.55995 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.43826 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4675 GSE205163,GSE205164_9_v_4_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null lung disease GWASdb SNP-Disease Associations 1.0 0.186006 GSE154074_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.57486 RS411 CCLE Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 NCIH2066 CCLE Cell Line Gene Mutation Profiles 1.0 null dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52462 Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GC-1 spg cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.858 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.858552 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null Postsynaptic endocytic zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.1 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24593 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27283 YY1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-1426-SM-4KKZP GTEx Tissue Sample Gene Expression Profiles 1.0 0.839206 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BCKDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23409 CGTH-W-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KG1 CCLE Cell Line Gene CNV Profiles -1.0 -1.77562 GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04772 GTEX-WYBS-1126-SM-3NMAM GTEx Tissue Sample Gene Expression Profiles 1.0 0.992244 hsa-miR-1258 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null lung_3e HPA Tissue Sample Gene Expression Profiles 1.0 0.864957 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997922 PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17102 GNG14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0968 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.096 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18169 H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FXR MotifMap Predicted Transcription Factor Targets 1.0 null HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63644 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61081 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.7027 H3K4me1_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles 1.0 1.1987 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.959356 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03168 GTEX-P4PQ-0626-SM-3NMCU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMMY-0626-SM-33HBD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10993 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84745 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE118794_2_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03294 GSE199092_2_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE224599_0_v_1_tfcp2_human RummaGEO Gene Perturbation Signatures -1.0 null 624 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.8926 primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23766 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16174 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 Perturb_4823_KD_Chd4_SRP315519 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.09016 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3148 L540 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null P31FUJ CCLE Cell Line Gene CNV Profiles 1.0 1.33084 H3K27me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43571 transferase activity, transferring phosphorus-containing groups GO Molecular Function Annotations 2015 1.0 null LP1 CCLE Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0609 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06682 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 68.8544 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84427 ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MRPL19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06423 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13627 COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.29525 REST ENCODE Transcription Factor Targets 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.972835 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0126-SM-3GIJL GTEx Tissue Sample Gene Expression Profiles 1.0 0.874135 hsa-miR-940 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12203 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9685 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.721 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-1626-SM-47JYN GTEx Tissue Sample Gene Expression Profiles 1.0 0.853392 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.969223 CAL78 CCLE Cell Line Gene Mutation Profiles 1.0 null HSC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null CBP-20019798-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE136622_6_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0937 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5155 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DPY19L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05604 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 purine ribonucleoside triphosphate binding GO Molecular Function Annotations 2015 1.0 null nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Salivary_Gland-ionocyte Tabula Sapiens Gene-Cell Associations 1.0 1.18394 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1208 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88905 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.66337 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.428325 hsa-miR-548x TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.096 GNAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2333 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.95 SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.53717 CEBPD-21427703-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.049968 carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.072339 DDX3X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11085 BRCA1 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3940-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48257 H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.8679 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE196671_5_v_8_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE240027,GSE240030_5_v_2_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHPG-0826-SM-3NMBF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-XMK1-1026-SM-4B65H GTEx Tissue Sample Gene Expression Profiles 1.0 0.963509 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null SK-MEL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.29544 DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946922 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 2.12608 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3246 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null myb_16205643_primary_monocytes_gof_human_gpl570_gse2816 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.027224 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.049999 GTEX-T5JC-2126-SM-32PMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06219 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null LPS510 DepMap CRISPR Gene Dependency 1.0 2.12491 Klinefelter syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CD4_Memory_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.957186 posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14856 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AI-1126-SM-48U19 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02634 GSE179974_3_v_1_carboplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.54428 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0606 Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.3537 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4371 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE155031_5_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bj HPA Cell Line Gene Expression Profiles -1.0 -1.05471 GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.18552 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WH7G-0726-SM-3NMBM GTEx Tissue Sample Gene Expression Profiles 1.0 0.970217 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.21702 H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.849491 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.175 ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE211983_1_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE218727_2_v_1_zkscan3_human RummaGEO Gene Perturbation Signatures 1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6227 Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRF_02_21 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.52356 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3288 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0926-SM-3LK7T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.2525 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Septin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.686 MRPL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56026 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.005 GSE244072_10_v_3_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null HOXB7-26014856-BT474-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.1419 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SH2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72996 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.22246 UMUC9 DepMap CRISPR Gene Dependency 1.0 2.10866 Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.962 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.905312 SF3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18802 abnormal sperm head morphology MGI Mouse Phenotype Associations 2023 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TOV21G CCLE Cell Line Gene Expression Profiles -1.0 -1.68261 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20196 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BV-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.94072 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 0.926759 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19161 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928021 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null mast cells BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23002 H3K27ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH1563 CCLE Cell Line Gene CNV Profiles -1.0 -1.43166 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.06511 G118 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15859 ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE136622_7_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IRF4-20064451-CD4+T-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963854 DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.39424 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16552 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.923713 vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.20387 OVCAR5 CCLE Cell Line Gene CNV Profiles 1.0 1.87496 GSE254517_1_v_0_irf7_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54534 EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0576 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17384 GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.21362 DAOY CCLE Cell Line Gene CNV Profiles 1.0 1.58177 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hepg2 HPA Cell Line Gene Expression Profiles -1.0 -1.05471 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Flagellum attachment zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.711 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8129 EBF1 ENCODE Transcription Factor Targets 1.0 null GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958855 inner SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.84971 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Zymogen granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.878 primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03468 heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL28 CCLE Cell Line Gene Expression Profiles 1.0 1.66505 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spermatogenic failure 16 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.179 EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null Inner dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.395 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.83565 KARPAS422 CCLE Cell Line Gene Expression Profiles 1.0 1.45759 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7833 NOMO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.69183 skbr3 HPA Cell Line Gene Expression Profiles -1.0 -1.05471 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.525 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37054 Scrotum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.758 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles 1.0 0.838149 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-1207-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFON-1626-SM-4LVMV GTEx Tissue Sample Gene Expression Profiles 1.0 0.977064 anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.951787 WM1799 CCLE Cell Line Gene Expression Profiles 1.0 1.44969 GTEX-QV44-2226-SM-447A3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909423 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.206 H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FCF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03469 CYB5R3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24046 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.71818 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1638 Cellular anatomical entity COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 2.285 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALKBH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21041 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66741 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7342 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.19488 SCC90 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48875 FNBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17694 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE211286_7_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55612 GTEX-P4QT-1726-SM-2S1NQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891216 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null HCC1359 CCLE Cell Line Gene Mutation Profiles 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11268 KDM5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21604 H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910981 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D6-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPARD ChEA Transcription Factor Targets 1.0 null H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11605 SKCO1 CCLE Cell Line Gene CNV Profiles 1.0 1.95792 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910981 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH716 CCLE Cell Line Gene Mutation Profiles 1.0 null RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIRT6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-513b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8178 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34742 Plasma membrane bounded cell projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.808 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 NCIH1623 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.3291 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28471 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9684 PLCD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27922 NCIH446 CCLE Cell Line Gene Expression Profiles -1.0 -2.28409 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE192870_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-428-MYF5_MYF5 Rummagene Transcription Factor Associations 2026 1.0 null striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.68502 G124 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.50039 CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.71862 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05371 DDX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36613 Sperm head-tail coupling apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.865 rpmi8226 HPA Cell Line Gene Expression Profiles -1.0 -1.05471 Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WOFL-0126-SM-3MJG2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28482 PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null 496100465_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07692 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null GSE60691_0_v_1_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-1526-SM-4DM68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04152 COLO-320-HSR COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53298 EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4507 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ciliated cell_Trachea_Mouse CellMarker Gene-Cell Type Associations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-922 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.664 lymphnode_5a HPA Tissue Sample Gene Expression Profiles -1.0 -0.848393 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2316 cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45282 Secretory granule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 NCIH1299 CCLE Cell Line Gene Mutation Profiles 1.0 null esophagus HPA Tissue Gene Expression Profiles -1.0 -0.984447 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.70024 GTEX-XPVG-0926-SM-4B651 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.893551 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7104 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.56161 GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures -1.0 null HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8198 H3K27me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CORL24 CCLE Cell Line Gene Expression Profiles 1.0 2.00263 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08452 PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2 Rummagene Transcription Factor Associations 2026 1.0 null Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.559 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.830801 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-1106P COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RM2N-0626-SM-48FD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 JUN-27471255-CHONDROCYTES-MOUSE-RIB ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGF1R-20145208-DFB-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ventrolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.906284 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAPCA2B CCLE Cell Line Gene Expression Profiles -1.0 -1.64906 GSE169205_0_v_5_sirt5_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE171837_0_v_2_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35828 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14801 Microtubule bundle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.958 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32091 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.953268 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Sperm principal piece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.024 Metabolic Syndrome X HuGE Navigator Gene-Phenotype Associations 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE217694_3_v_0_pold1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23221 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1 ChEA Transcription Factor Targets 1.0 null HS 683 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05657 SOX3-22085726-MUSCLE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.28775 Perturb_4525_KO_Chaf1a_ERP006640 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.2452 GTEX-SIU7-1626-SM-4BRUK GTEx Tissue Sample Gene Expression Profiles 1.0 1.27141 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6906 HOXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69896 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11964 P-Selectin dbGAP Gene-Trait Associations 1.0 1.38677 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.47685 SKMEL5 CCLE Cell Line Gene Expression Profiles 1.0 2.09695 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1774 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 2.07997 Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVJO-0526-SM-447CE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XUW1-1026-SM-4BONY GTEx Tissue Sample Gene Expression Profiles 1.0 1.00927 GSE210682_2_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.82852 fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.901818 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.836431 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.900884 Rectum adenocarcinoma_READ_TCGA-AG-4022-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.919787 mcf7 HPA Cell Line Gene Expression Profiles -1.0 -1.05471 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 MCAD_KO_GDS4546_423_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE244072_10_v_8_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.98 GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null LN464 CCLE Cell Line Gene Expression Profiles 1.0 1.60558 dorsolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61032 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.1571 PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN Rummagene Transcription Factor Associations 2026 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DDX59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35442 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ciliary tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.105 inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16174 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.74252 Perturb_4471_KO_Prdm12_SRP334439 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.02273 Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.72886 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7271 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 2.07044 Perturb_12771_KO_Bin1_SRP201679 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.16916 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.43018 HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.856407 Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.969 striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.993245 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.88578 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 0.843918 Lung adenocarcinoma_LUAD_TCGA-93-A4JO-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838472 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.916397 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916057 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 1.32719 CXorf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49772 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VPS37A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2515 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE164874_5_v_3_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.54651 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93101 hsa-miR-548ae TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 D283MED CCLE Cell Line Gene CNV Profiles -1.0 -1.68288 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.884692 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.50039 GTEX-PX3G-0326-SM-2I3EO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 SOX5 JASPAR Predicted Transcription Factor Targets 1.0 null H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2484 POU2AF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72805 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-0526-SM-2I3ED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08184 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8373 PSMB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23447 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE118794_0_v_4_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RVPU-0008-SM-3NM8B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65772 primary auditory cortex (core)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09288 TGBC11TKB CCLE Cell Line Gene Mutation Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0526-SM-4BOON GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 RFX5 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRK-0526-SM-3NB2F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894098 GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23938 GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GK_KO_GDS2610_162_mouse_Brown adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-Q2AH-2026-SM-2S1PX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-NFK9-0526-SM-2YUNL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20801 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22769 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMK2N1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15696 FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_14216_KO_Igf1r_SRP081104 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.2475 ESD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8107 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATM_KD_GSE54268_661_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BL3907 (USP28) NURSA Protein Complexes 1.0 null nucleoside monophosphate kinase activity GO Molecular Function Annotations 2023 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE113385_0_v_1_six1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.878 PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18 Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844509 GSE87412,GSE92423_3_v_4_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.2441 YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.049998 WRNIP1 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20786 skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.34444 Intracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-Q2AG-0011-R9A-SM-2HMJ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30215 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null hsa-miR-1226 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intraciliary transport particle A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.023 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.741094 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.952 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1395 CCLE Cell Line Gene CNV Profiles 1.0 1.72317 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07733 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12751 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.899133 SIX5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06873 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06802 SMAD4 ChEA Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.888915 KYSE520 CCLE Cell Line Gene CNV Profiles -1.0 -1.50461 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52959 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3374 23132/87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944807 59M DepMap CRISPR Gene Dependency 1.0 3.9857 posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937822 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33532 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.7809 PPP1R2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44183 AKAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04111 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35753 GTEX-S4Q7-1026-SM-4AD75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22043 496100337_HIP_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3935 GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.48045 Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130383_2_v_3_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.96111 GSE120370_4_v_1_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2398 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.932055 KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.26293 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.8 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54321 echocardiography GAD Gene-Disease Associations 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.93701 H3K27me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.87221 primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0068 urinary bladder HPA Tissue Protein Expression Profiles 1.0 0.859011 abnormal motor neuron morphology GWASdb SNP-Phenotype Associations 1.0 0.443596 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.5051 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06252 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.05681 abnormal spermatogenesis MGI Mouse Phenotype Associations 2023 1.0 null SW948 DepMap CRISPR Gene Dependency 1.0 5.73047 Perinuclear theca COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.808 GTEX-S7SE-0008-SM-33HB1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.982194 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6997 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8428 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6749 TE-9 COSMIC Cell Line Gene CNV Profiles -1.0 -3.36169 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MITF ChEA Transcription Factor Targets 1.0 null binding GO Molecular Function Annotations 2015 1.0 null POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0381 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9967 OV90 CCLE Cell Line Gene Mutation Profiles 1.0 null RKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11964 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERG-20517297-VCAP-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null carotid artery diseases GAD Gene-Disease Associations 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.61386 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06141 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null cilium assembly GO Biological Process Annotations 2023 1.0 null MMS22L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22005 GTEX-XUZC-0626-SM-4BOPG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12765 ASPC1 DepMap CRISPR Gene Dependency 1.0 4.23647 MRGBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17353 Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.10992 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.960962 nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.484944 tobacco use disorder GAD Gene-Disease Associations 1.0 null Axonemal central apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.145 Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196318_0_v_1_xpo4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-QESD-0526-SM-2I5G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848859 GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE139975_3_v_1_rnf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null GTEX-WOFL-0726-SM-3MJG4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15269 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.932591 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8315 GTEX-XUZC-1026-SM-4BOPY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889996 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 1.08882 Katanin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.506 GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13286 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859865 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.705 GTEX-O5YW-0326-SM-2I5EI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Cortical layer of collagen and cuticulin-based cuticle extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.798 H3K9ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CAL-148 COSMIC Cell Line Gene Mutation Profiles 1.0 null HS936T DepMap CRISPR Gene Dependency 1.0 2.19812 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-2026-SM-3LK7U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829539 YY1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.875237 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.03744 GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00171 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23221 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IST-MES1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0054 SNUC4 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.132 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.872713 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045576 GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE118794_2_v_1_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null Alx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.0094 lung HPA Tissue Gene Expression Profiles 1.0 1.07158 496100519_HIP_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10779 ELK1_01_162 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61329 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8140-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.840995 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.863509 Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2975 GTEX-QXCU-0326-SM-2TC63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18792 SINHCAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77418 Corpus epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.789 GTEX-RN64-1226-SM-2TC6E GTEx Tissue Sample Gene Expression Profiles 1.0 0.921601 PMC7518873-abb0205_Table_S1.xls-TFEB_targets-symbol_TFEB Rummagene Transcription Factor Associations 2026 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.00731 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gracile nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24307 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45054 HOS CCLE Cell Line Gene Expression Profiles -1.0 -1.88715 TE5 CCLE Cell Line Gene CNV Profiles -1.0 -2.0538 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Intracellular anatomical structure COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 2.285 heart muscle HPA Tissue Protein Expression Profiles 1.0 0.859011 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.84937 Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null decreased male germ cell number MGI Mouse Phenotype Associations 2023 1.0 null ST6GAL1_Deficiency_GDS3151_608_mouse_Mammary tumors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.979208 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-398 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01454 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3449 abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.161333 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.952 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02374 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.943966 GTEX-S3XE-0008-SM-3NM8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.14414 TFAP2C ChEA Transcription Factor Targets 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902011 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.2473 Frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.083 GSE217115_2_v_4_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.81686 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.87689 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04738 PMC12673788-12967_2025_7484_MOESM5_ESM.xlsx-OCT4_cor_p_0_4-gene_id_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U3ZM-0008-SM-4DXTQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.33636 YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38919 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Axonemal outer doublet COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.342 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.0956 Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sigmoid_Colon Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.66038 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.890448 Egg coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.986 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23918 Ebolavirus(ZEBOV)_5day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.16764 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.41449 GSE185163_5_v_2_clic4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.20016 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles 1.0 0.977023 H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Central cylinder COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.833 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTP4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10139 CI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40751 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.02613 HT55 CCLE Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null Mantle cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.074 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.32149 LOVO CCLE Cell Line Gene Mutation Profiles 1.0 null smooth muscle HPA Tissue Protein Expression Profiles 1.0 0.859011 GTEX-S7SE-0926-SM-2XCD6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02605 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.902962 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.04262 GSE150134_1_v_0_fluorouracil_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10387 H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.88251 ERG ChEA Transcription Factor Targets 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4467_KO_Cnr1_SRP346447 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.57002 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0008-SM-48TE9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13603 GTEX-S95S-1326-SM-2XCDK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.892355 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2012 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POMQ-0326-SM-2I5FO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958196 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.840712 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 RPS3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01619 Cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040628 Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.455 GSE101336_1_v_0_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920255 GTEX-WL46-0726-SM-3LK5Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00609 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00544 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null purine ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.038293 ETS1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836451 SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10077 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-A4BY-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.911802 GSE230263,GSE230265_5_v_1_runx1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 1.30064 CL-40 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC9 CCLE Cell Line Gene Mutation Profiles 1.0 null ARHGEF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34937 posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22194 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.941776 C21orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01838 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.89945 GTEX-OIZF-1526-SM-3MJGY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.926597 GTEX-U4B1-1426-SM-4DXTX GTEx Tissue Sample Gene Expression Profiles 1.0 1.15264 CLIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02506 Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_4532_KD_Sumo2_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.39417 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARFGEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25079 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0739 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.828743 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16174 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 2.01312 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S32W-0126-SM-4AD61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.901135 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99606 GSE111385_0_v_1_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Fetal_Brain_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.1084 GSE157960_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.056 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-1526-SM-4AD6K GTEx Tissue Sample Gene Expression Profiles 1.0 1.04964 GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5025 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0486 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13373 cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 chaperonin-containing T-complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 intracellular part GO Cellular Component Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3324-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Echocardiography dbGAP Gene-Trait Associations 1.0 0.472462 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0856 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.54908 GSE180951_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.933185 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866625 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35846 NCIH1437 CCLE Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS936T CCLE Cell Line Gene Expression Profiles 1.0 1.72866 KO52 CCLE Cell Line Gene CNV Profiles -1.0 -1.87293 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HEC6 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SRC_overexpression_276_GSE37428 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.44586 SPI1 ENCODE Transcription Factor Targets 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.839427 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.1133 GSE210101,GSE210114_5_v_10_urod_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFG8-2126-SM-3GIKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.11474 Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978565 GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39291 HS940T CCLE Cell Line Gene Expression Profiles -1.0 -1.70162 KMS-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889444 abnormal manchette morphology MGI Mouse Phenotype Associations 2023 1.0 null HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4492 GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null Secretory vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24741 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842569 GSE240896,GSE240899_10_v_0_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null RCC-FG2 COSMIC Cell Line Gene Mutation Profiles 1.0 null teratozoospermia MGI Mouse Phenotype Associations 2023 1.0 null COLO849 CCLE Cell Line Gene Expression Profiles 1.0 1.45216 VMRC-RCZ COSMIC Cell Line Gene Mutation Profiles 1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 GSE216043_11_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2849 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880629 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.953648 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3385 GSE155031_6_v_2_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36816 TEAD4 ChEA Transcription Factor Targets 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16122 organelle part GO Cellular Component Annotations 2015 1.0 null H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14322 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178714_6_v_7_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE130956_2_v_1_icaritin_human RummaGEO Drug Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9094 PRKCZ_KO_GDS4310_293_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null C4II DepMap CRISPR Gene Dependency 1.0 2.59774 RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6481 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32015 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49446 ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41195 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null SW480 CCLE Cell Line Gene Mutation Profiles 1.0 null SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05223 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83518 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03412 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05061 H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 4.38301 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.66704 IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946922 Cornelia de Lange syndrome 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.383 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FTC133 CCLE Cell Line Gene CNV Profiles 1.0 1.43681 CHD1 ENCODE Transcription Factor Targets 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.06975 H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UVSSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33714 Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.8928 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-1726-SM-2I5FX GTEx Tissue Sample Gene Expression Profiles 1.0 0.954993 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null Carotid Artery Diseases dbGAP Gene-Trait Associations 1.0 0.647716 GSE168676_2_v_3_dach1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormal manchette perinuclear ring morphology MGI Mouse Phenotype Associations 2023 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.914354 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.898196 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879163 SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950836 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.12056 GSE103068_0_v_3_volasertib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964549 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0826-SM-2TF5C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17667 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53127 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.39089 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14801 GTEX-PWCY-0426-SM-48TCW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null adenyl nucleotide binding GO Molecular Function Annotations 2015 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA13_HOXA13 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GE-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Axonemal microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.049 Perineuronal net COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.861 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MPP89 CCLE Cell Line Gene CNV Profiles -1.0 -1.33174 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE189683_1_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null OCUG1 DepMap CRISPR Gene Dependency 1.0 10.3845 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMRM-0626-SM-447BQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.979749 YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.707 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE185944_2_v_4_pth1r_mouse RummaGEO Gene Perturbation Signatures 1.0 null fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.950084 acute leukemia GWASdb SNP-Disease Associations 1.0 0.692909 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE159937_2_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SARS-CoV MA15_Day7-CXCR3KO_None_GSE50878 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.19212 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null D458 DepMap CRISPR Gene Dependency 1.0 2.09829 FMNL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24851 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1 Rummagene Transcription Factor Associations 2026 1.0 null CAL-78 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pursuit maintenance gain GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 AR-21572438-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.831692 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835195 RUNX3 ENCODE Transcription Factor Targets 1.0 null decreased testis weight MGI Mouse Phenotype Associations 2023 1.0 null guanylate kinase activity GO Molecular Function Annotations 2023 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Get-1_Deficiency_GDS2629_161_mouse_embryonic skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null hematologic cancer GWASdb SNP-Disease Associations 1.0 0.303879 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.36 NCI-H1299 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endomembrane system COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 ion binding GO Molecular Function Annotations 2015 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.69582 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.903544 Perturb_16956_Mut_Kif1b_SRP094648 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.62331 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 esophagus_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56316 WDR12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18842 GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.927234 PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6C-Table_S6C_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_PRAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1155 CCLE Cell Line Gene Expression Profiles -1.0 -1.47912 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8572 Perturb_5212_OE_Pten_SRP154291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.33034 ARSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23553 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21473 fallopian tube HPA Tissue Gene Expression Profiles 1.0 2.24804 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07158 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44924 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.28628 GTEX-X4XX-0926-SM-46MV7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.91249 NCI-H146 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-0226-SM-2XCAX GTEx Tissue Sample Gene Expression Profiles 1.0 0.955348 bronchus HPA Tissue Protein Expression Profiles 1.0 0.859011 SUZ12 ENCODE Transcription Factor Targets 1.0 null C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.889935 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.057 Manchette COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Sleep disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.01 RCM1 DepMap CRISPR Gene Dependency 1.0 3.46738 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-0226-SM-2TC5W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GTEX-WFG8-1826-SM-4LVM4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00299 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.28449 GSE217115_2_v_0_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWOO-0526-SM-2S1Q3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00672 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.31116 Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 OCIMY7 DepMap CRISPR Gene Dependency 1.0 2.11341 midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29131 KMRC20 CCLE Cell Line Gene CNV Profiles 1.0 1.53569 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RTLS-0426-SM-2TF5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15218 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE171837_1_v_2_bortezomib_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE151612_4_v_11_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.858 KDM4A ENCODE Transcription Factor Targets 1.0 null neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.234123 GTEX-WYJK-1626-SM-3NM9J GTEx Tissue Sample Gene Expression Profiles 1.0 0.833504 immune system cancer GWASdb SNP-Disease Associations 1.0 0.303879 RPL22L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37975 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25212 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08567 SNU738 DepMap CRISPR Gene Dependency 1.0 2.7932 MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3607 GTEX-Q2AH-0726-SM-2I3EA GTEx Tissue Sample Gene Expression Profiles 1.0 0.988877 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9807 HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.52133 GSE247775_1_v_0_tmprss2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUZC-0426-SM-4BOPE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972685 Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.698 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.979946 PMC11462941-CAS-115-2947-s001.pdf-171-JDP2_JDP2 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NM-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02903 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 0.964507 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.23321 GSE208350_4_v_1_fgfr1_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64886 all GWASdb SNP-Phenotype Associations 1.0 0.034866 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A8YH-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06034 Fer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.746 YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16100_KO_Map3k12_SRP157873 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.42097 raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11759 GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CALD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19846 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11148097-41698_2024_569_MOESM2_ESM.pdf-213-ZNF277_ZNF277 Rummagene Transcription Factor Associations 2026 1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896018 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.7607 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX Rummagene Transcription Factor Associations 2026 1.0 null TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4543 496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.4013 TSSK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14898 GTEX-W5X1-0526-SM-3GILH GTEx Tissue Sample Gene Expression Profiles 1.0 0.864443 GTEX-UJMC-0526-SM-3GAE3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.9516 SUIT2 DepMap CRISPR Gene Dependency 1.0 2.01778 CEBPA-26348894-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-QEL4-2126-SM-447AE GTEx Tissue Sample Gene Expression Profiles 1.0 0.82854 Nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.974 SMC3 ENCODE Transcription Factor Targets 1.0 null GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04007 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null mycophenolate mofetil_homo sapiens_gpl4133_gse45485 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7288 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.5533 CDK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27135 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61561 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997922 SAP30 ENCODE Transcription Factor Targets 1.0 null COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18369 496100570_HIP_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.027 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01326 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC151 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.15199 Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7778 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lymphoma GWASdb SNP-Disease Associations 1.0 0.532414 Obesity HuGE Navigator Gene-Phenotype Associations 1.0 null GSE231745_1_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.876 GTEX-X5EB-0626-SM-46MVQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 JHUEM7 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC7518873-abb0205_Table_S1.xls-TFEB_targets-ensembl_TFEB Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.952635 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H720 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 0.961554 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5668 GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.954476 thiamine_rattus norvegicus_gpl2896_gse19292 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943203 cis-Golgi network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.541 H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null SIN3A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47873 GTEX-XGQ4-2426-SM-4AT55 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985632 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885908 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3714 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.859778 P-loop containing nucleoside triphosphate hydrolase InterPro Predicted Protein Domain Annotations 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.4888 PAX5 ENCODE Transcription Factor Targets 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11233 GSE130383_2_v_0_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0182 GTEX-WK11-2426-SM-3NMAA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14189 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.2073 KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22604 YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPK-0326-SM-2HMJO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null COLO829 CCLE Cell Line Gene CNV Profiles 1.0 1.35893 NCOR1-26117541-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.148 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34192 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1338 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00732 SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 69.9574 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.7309 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955288 GSE131660_1_v_0_piperlongumine_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89259 GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles 1.0 1.33696 Lung squamous cell carcinoma_LUSC_TCGA-L3-A4E7-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211983_0_v_3_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null 2313287 CCLE Cell Line Gene CNV Profiles -1.0 -1.78929 CORL88 CCLE Cell Line Gene Expression Profiles 1.0 1.35035 GSE70499_3_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC7806950-mmc3.xlsx-Sheet5-Table_S3_Comparison_of_DEGs_following_targeting_of_dSaCas9-repressors_to_DUX4_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null 786-O Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877671 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.858552 TSR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22427 L33 CCLE Cell Line Gene CNV Profiles -1.0 -1.60366 respiratory system disease GWASdb SNP-Disease Associations 1.0 0.169423 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.086621 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.96462 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null synapse-associated extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.857 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.0724 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28333 Right_Atrium Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.880806 PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FTC133 CCLE Cell Line Gene Mutation Profiles 1.0 null GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null AKT1_Activation - 6 week induction_GDS2308_718_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BCLAF1_01_214 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.82936 GTEX-S4Q7-0326-SM-3K2B1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835574 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE145639_1_v_6_adar_human RummaGEO Gene Perturbation Signatures 1.0 null KDM2B-26808549-CHIP-SEQ-REH-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X3Y1-0626-SM-3P5YS GTEx Tissue Sample Gene Expression Profiles 1.0 1.35508 Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nuclear part GO Cellular Component Annotations 2015 1.0 null SIX5_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16115_KO_Map3k12_SRP157873 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.86973 NCIH2228 CCLE Cell Line Gene CNV Profiles -1.0 -1.54788 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5172 LU99 CCLE Cell Line Gene CNV Profiles -1.0 -2.00444 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.90297 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83611 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.858552 COLO800 DepMap CRISPR Gene Dependency 1.0 3.1155 LU99 CCLE Cell Line Gene Mutation Profiles 1.0 null JUN-21703547-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS294T DepMap CRISPR Gene Dependency 1.0 4.72858 motor neuron atrophy GWASdb SNP-Phenotype Associations 1.0 0.443596 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18537 MTA3 ENCODE Transcription Factor Targets 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.027 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21678 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFX_KO_GDS2718_150_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H2023 COSMIC Cell Line Gene Mutation Profiles 1.0 null Blood Pressure dbGAP Gene-Trait Associations 1.0 0.661727 Perturb_11484_KO_Mir183_SRP107957 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.885634 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -1.26289 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NALM-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.829476 GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null MCF7_CUDC-101_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.00970745 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE155305_2_v_1_ifitm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_9_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8175 K-562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20622 Attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.543 rab9 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.05 fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 1.59852 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.58859 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53298 cell part LOCATE Predicted Protein Localization Annotations 1.0 null NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRL-0008-SM-3NB29 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2758 GSE131161_2_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC3348545-NIHMS263168-supplement-3.pdf-215-PAX4_PAX4 Rummagene Transcription Factor Associations 2026 1.0 null PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.24909 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04514 GTEX-P4QT-0008-SM-48TDZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07845 PANC1005 DepMap CRISPR Gene Dependency 1.0 4.67078 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 shsy5y HPA Cell Line Gene Expression Profiles 1.0 1.08506 GTEX-S95S-0226-SM-4B656 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997518 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.921711 SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Lassa Fever Virus_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.03723 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null GTEX-XGQ4-0526-SM-4AT6C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00942 GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0618 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11155 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.04389 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POMQ-0526-SM-3GADD GTEx Tissue Sample Gene Expression Profiles 1.0 0.830282 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE110178_5_v_0_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Implantation fossa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.08 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0626-SM-4BOOO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.939932 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.82289 H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WFG8-0626-SM-3GILJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1057 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null SK-N-SH Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.994577 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S32W-0726-SM-2XCBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.830773 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.915404 GSE198165,GSE198166_5_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835793 CD4_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.14896 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H4K20me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968581 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26821 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.993628 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUDHL4 DepMap CRISPR Gene Dependency 1.0 2.22145 CAOV3 CCLE Cell Line Gene Expression Profiles -1.0 -1.54687 LTBR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00569 SIX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WH7G-1626-SM-4LVMY GTEx Tissue Sample Gene Expression Profiles 1.0 0.951444 motor neuron disease GWASdb SNP-Disease Associations 1.0 0.520031 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0188 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.72398 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.941614 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22779 SCC-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Ciliopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.445 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGR1 CCLE Cell Line Gene Expression Profiles 1.0 1.84579 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null REST_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL1 CCLE Cell Line Gene Expression Profiles 1.0 1.5832 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.1419 GTEX-SJXC-2026-SM-4DM6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.06254 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3557 GTEX-UJHI-1926-SM-3DB8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09427 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5241 GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.918987 nucleoside binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-0225-SM-4E3HO GTEx Tissue Sample Gene Expression Profiles 1.0 0.831797 hsa-miR-4506 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GTEX-X4EO-0926-SM-3P5Z2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04362 GSE88819_11_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KPNRTBM1 CCLE Cell Line Gene Mutation Profiles 1.0 null 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.18887 hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.243259 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.905168 FERD3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22882 mRNA_OTX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal neuron morphology GWASdb SNP-Phenotype Associations 1.0 0.443596 PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.70957 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.504 H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53473 GSE129241_4_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4514 SIN3A ENCODE Transcription Factor Targets 1.0 null NCI-H187 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.64169 Perturb_6431_KD_ADAR_SRP268834 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.20772 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.51 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.192 PMC9314667-Table_1.xlsx-Regulons-MITF_MITF Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08419 GSE214823,GSE214824_0_v_2_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures -1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.543 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5218 CGTHW1 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE216147_0_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1437 COSMIC Cell Line Gene Mutation Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24987 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GSE129389_0_v_7_tropifexor_mouse RummaGEO Drug Perturbation Signatures 1.0 null BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30062 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.857614 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842298 GTEX-XMK1-2626-SM-4B65R GTEx Tissue Sample Gene Expression Profiles 1.0 0.912584 WHSC1 ENCODE Transcription Factor Targets 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-0926-SM-2I5FU GTEx Tissue Sample Gene Expression Profiles 1.0 0.869404 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10644 H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.597 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.63 GTEX-NFK9-2226-SM-3MJGP GTEx Tissue Sample Gene Expression Profiles 1.0 0.937077 SKMEL31 CCLE Cell Line Gene CNV Profiles 1.0 1.43625 A549_Belinostat_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.00993396 AR ChEA Transcription Factor Targets 1.0 null TNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38187 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44467 at1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.949 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.873029 MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-2626-SM-2HMJM GTEx Tissue Sample Gene Expression Profiles 1.0 0.93236 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Glucosidase II complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.863 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02534 H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RVH421 CCLE Cell Line Gene Expression Profiles 1.0 1.53471 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 JHH-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4291 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05634 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.862 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5906 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 Perturb_4534_KD_Ube2i_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.43969 GTEX-QLQ7-0526-SM-2I5G3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84482 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.8668 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.967058 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MELJUSO DepMap CRISPR Gene Dependency 1.0 2.46652 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HOXA5_HOXA5 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57965 PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF556 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14021 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32446 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.05173 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49446 OC316 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.81876 RPS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55148 GNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24863 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0661 hsa-miR-548aj TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SBK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18188 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal spermatid morphology MGI Mouse Phenotype Associations 2023 1.0 null RTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02936 NR2C2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 SW579 CCLE Cell Line Gene Mutation Profiles 1.0 null EP300 ChEA Transcription Factor Targets 1.0 null Intraciliary transport particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.303 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.296 GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.946336 EZH2 ENCODE Transcription Factor Targets 1.0 null SW620 COSMIC Cell Line Gene Mutation Profiles 1.0 null LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.997239 HEC108 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null microtubule bundle formation GO Biological Process Annotations 2023 1.0 null SNU466 CCLE Cell Line Gene CNV Profiles 1.0 1.94139 PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GSE70499_3_v_1_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE129772_2_v_3_runx3_mouse RummaGEO Gene Perturbation Signatures 1.0 null cellular component assembly GO Biological Process Annotations 2025 1.0 null 496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.55567 WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335968 acute leukemia GWASdb SNP-Phenotype Associations 1.0 0.379018 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.950836 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.41692 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 hsa-miR-4736 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Platelet dense tubular network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.359 PMC4029819-pone.0098069.s004.xlsx-SAM_FOXA1_h_vs_FOXA1_l-Table_S3_SAM_analysis_of_FOXA1_high_versus_FOXA1_low_cases_FDR_0_01_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null cilium assembly GO Biological Process Annotations 2025 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NB1643 DepMap CRISPR Gene Dependency 1.0 4.39903 GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 1.09831 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.345 GSE226091,GSE226092_0_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9799 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.3366 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 MDAMB415 DepMap CRISPR Gene Dependency 1.0 3.84689 UNC119B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16312 YY1 ChEA Transcription Factor Targets 1.0 null mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE148066,GSE157787_5_v_4_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null absent sperm flagellum MGI Mouse Phenotype Associations 2023 1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.7522 EZH2-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824904 ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.9293 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C32 CCLE Cell Line Gene CNV Profiles 1.0 2.8635 ELK1 ENCODE Transcription Factor Targets 1.0 null GTEX-U3ZM-0926-SM-4DXSW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20242 SIN3B ChEA Transcription Factor Targets 1.0 null GTEX-P4QT-1826-SM-2S1NJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Oligoasthenoteratozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.671 Lassa Fever Virus_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.76892 TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal sperm axoneme morphology MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE99187_1_v_0_gemcitabine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 4star Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.891783 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null lymphoblastic leukemia GWASdb SNP-Disease Associations 1.0 0.441889 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBED1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2923 ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.85947 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null TMEM82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11057 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.44146 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null ntera2 HPA Cell Line Gene Expression Profiles 1.0 1.91837 PMC5770158-elife-31706-supp3.xls-ISL1_target_regions-Nearest_gene_1_ISL1 Rummagene Transcription Factor Associations 2026 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.52222 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE110268_1_v_3_foxd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE128730_4_v_2_neratinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE154197_1_v_0_ints13_human RummaGEO Gene Perturbation Signatures 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22651 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07063 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.543 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MYO10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36901 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9774 H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CL40 CCLE Cell Line Gene Mutation Profiles 1.0 null layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927884 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.862 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 1.02676 HCT15 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE217378_2_v_0_lin28b_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OIZH-2026-SM-3NB1M GTEx Tissue Sample Gene Expression Profiles 1.0 1.26163 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.981961 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.852589 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null CTR9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57871 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04257 YY1 ENCODE Transcription Factor Targets 1.0 null PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 SLC25A15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67187 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40113 GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MTHFD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65696 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11543 primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.840064 SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-PSDG-0526-SM-2S1OH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59985 GSE112365_0_v_1_sirt1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100515_HIP_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00947 Heart Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null CD8_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.09851 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05812 G361 CCLE Cell Line Gene Expression Profiles 1.0 1.74837 GSE217541,GSE217543_3_v_2_tet1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE203655_0_v_1_stat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-V1D1-0826-SM-3P5ZA GTEx Tissue Sample Gene Expression Profiles 1.0 1.03075 PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22 Rummagene Transcription Factor Associations 2026 1.0 null UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.24658 RPLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01 PMC12673788-12967_2025_7484_MOESM5_ESM.xlsx-OCT4_cor_p_0_4-gene_name_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NPJ8-0526-SM-3MJHN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09272 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Perturb_4528_KD_Chaf1a_SRP060878 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.8405 Perturb_13644_KD_Trim28_SRP126388 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.4169 PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null CHL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.23125 YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CV-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.86177 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CAL148 CCLE Cell Line Gene Mutation Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58092 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles 1.0 1.13501 PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null NCIH1436 CCLE Cell Line Gene Expression Profiles -1.0 -1.53152 Smoking status (ever vs never smokers) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.730103 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null jf1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.691 COLO741 CCLE Cell Line Gene Expression Profiles 1.0 1.85297 Lhx8 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.2043 MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15859 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.074936 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RN64-1626-SM-48FD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882833 ZNF711 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1601 diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.159658 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null LANCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23955 phosphate-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null PRDM14 ChEA Transcription Factor Targets 1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null male infertility MGI Mouse Phenotype Associations 2023 1.0 null GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15286 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17033 SW48 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LM4_M2 MotifMap Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE155031_6_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5744 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null