association dataset threshold value standardized value 496100572_HIP_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.38991 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ntera2 HPA Cell Line Gene Expression Profiles 1.0 0.850813 GSE158458_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26742 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.39073 HL-60 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.48708 GSE158834_11_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17101 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59596 PHF8 ENCODE Transcription Factor Targets 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.93348 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RPL36A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04685 PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.860049 Perturb_11377_KD_TMEFF2_SRP153936 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.05572 TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36295 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4149 Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JQ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.932342 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100601_TCx_possible Alzheimer's disease_no TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.16988 CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66025 posterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.958711 GSE226249_2_v_8_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44867 bone marrow cancer GWASdb SNP-Disease Associations 1.0 0.452405 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44299 hsa-miR-4682 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HADHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50479 periventricular stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30576 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 1.57026 Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.8507 GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879428 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null NCIH2170 CCLE Cell Line Gene CNV Profiles -1.0 -1.65053 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12101 Chronic lymphocytic leukemia DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 EMC-BAC-2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.98885 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28124 HCFC1 ENCODE Transcription Factor Targets 1.0 null 19621087-Table1a GeneSigDB Published Gene Signatures 1.0 null GSE199255,GSE199356_0_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30405 H3K27me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27466 GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22637 MAPRE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46468 AHCTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14301 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27749 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.849374 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.43738 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35154 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32175 Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1296 Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38269 GSE157296,GSE157298_4_v_2_kbtbd4_human RummaGEO Gene Perturbation Signatures -1.0 null GSE84922,GSE84924_4_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures 1.0 null HAL-01 COSMIC Cell Line Gene Mutation Profiles 1.0 null pancreas HPA Tissue Gene Expression Profiles -1.0 -1.15767 GTEX-S33H-1126-SM-2XCB6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874098 fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 1.54898 SNU216 DepMap CRISPR Gene Dependency 1.0 2.22203 Renal cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 hsa-miR-429 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.92157 SEC22B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20374 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08097 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.52256 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-52-PRDM13_PRDM13 Rummagene Transcription Factor Associations 2026 1.0 null intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70198 H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29458 pou5f1_16518401_mesc_lof_mouse_gpl1261_gds1824 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.84098 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-93-3p MiRTarBase microRNA Targets 1.0 null cancer GWASdb SNP-Disease Associations 1.0 0.0659 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00282 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24786 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16201 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null GSE133516_5_v_6_kat7_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KE37 DepMap CRISPR Gene Dependency 1.0 2.25446 BANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2063 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles 1.0 1.17084 lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80648 H3K27ac_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04948 KIAA1522 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89457 mRNA_ESRRB_19136965 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Genital Diseases, Female CTD Gene-Disease Associations 1.0 1.04538 H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.53656 ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31877 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21608 posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38834 hsa-miR-559 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.984365 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6446 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1549 GATA3 ENCODE Transcription Factor Targets 1.0 null H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.16807 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.248462 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.24124 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71281 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE195663_0_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_1_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.12448 GSE242290_1_v_7_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25586 GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62202 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848403 GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00688 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BMI1-19503595-MEFC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE229671,GSE229673_2_v_1_yrdc_human RummaGEO Gene Perturbation Signatures -1.0 null Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.163 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969528 MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.972161 III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.865405 Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_7_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1384 Respiratory system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HUG1N CCLE Cell Line Gene CNV Profiles 1.0 2.34254 MXI1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE240386,GSE242143_1_v_4_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15496 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1916 Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33454 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22904 GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12458 Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.221 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842549 r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5701 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE129186,GSE129223_0_v_1_aicda_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE68925_1_v_0_fasudil_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3013 GSE217452_3_v_1_docetaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GSE173307,GSE173391_0_v_1_rgcc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.20226 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A4JJ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100373_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0538 GSE193258,GSE193259_5_v_4_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-581 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 0.990834 hsa-miR-4450 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34925 mRNA_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45061 H4K91ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.76014 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66349 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38032 Infralimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37023 Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.92942 PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-CO-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZIC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 74.6831 HS611T CCLE Cell Line Gene Expression Profiles 1.0 1.44484 TCF3 ChEA Transcription Factor Targets 1.0 null KDM5B-21448134-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CHL1 CCLE Cell Line Gene Expression Profiles 1.0 1.70258 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.415878 hsa-miR-4328 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.886062 hsa-miR-561 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 DDX54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40832 CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.68074 GSE169205_0_v_7_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.13621 Idiopathic pulmonary fibrosis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.21549 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null GSE175787_8_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142684_2_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NOP53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32423 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90865 KDM5B-21448134-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.71454 Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18138 Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12214 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04778 IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26381 SMTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78282 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.848699 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.25968 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5534 Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72842 Perturb_15515_KD_E2F2_SRP314859 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.88661 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.78162 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73771 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.95823 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32505 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE234289_4_v_1_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1061 MCAS COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.35315 GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16241 Monocyte count GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.852288 NANOG ChEA Transcription Factor Targets 1.0 null GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54809 CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27133 MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_ACTIVATED-RING1B_EWSR1-FLI1_activated_genes_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26782 posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852931 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Primary visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35427 GAS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38428 GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20975 D542MG DepMap CRISPR Gene Dependency 1.0 4.20448 ventral nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12247 FBN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95487 muscle GTEx Tissue Gene Expression Profiles -1.0 -1.06386 GSE189683_3_v_0_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF-21964334-BJAB-B-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.93158 16912175-SuppTable3b GeneSigDB Published Gene Signatures 1.0 null NCIH3255 CCLE Cell Line Gene CNV Profiles 1.0 1.3428 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30526 CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BATF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE230263,GSE230265_5_v_1_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22902 Hepatoma ascites cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.596 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 0.929687 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STK33_SKM MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GLIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.594 MFE-280 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81813 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Contractile ring COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.428 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.239 Ciliated cell_Trachea_Mouse CellMarker Gene-Cell Type Associations 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896751 hepg2 HPA Cell Line Gene Expression Profiles -1.0 -1.25586 GTEX-WHSE-0126-SM-3NMBT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.895894 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12582 intermedioposterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12686 Kidney cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 DHRS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02158 CENPW CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32267 PLCG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21197 Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00883 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07963 H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5905-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3617 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE199255,GSE199356_3_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71175 Endocrine gland cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.058 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.948553 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9894 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00852 GTEX-S4Q7-1126-SM-4AD6R GTEx Tissue Sample Gene Expression Profiles 1.0 0.874826 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.879778 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Wnt-Frizzled-LRP5/6 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.626 GSE142210_9_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE95077_1_v_3_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45061 Interstitial lung disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.20969 GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 0.842516 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE198165,GSE198166_0_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-109-MTF2_MTF2 Rummagene Transcription Factor Associations 2026 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29065 NRF1 ENCODE Transcription Factor Targets 1.0 null ATP5PD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08071 GSE198165,GSE198166_6_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE216273,GSE216292_14_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.83804 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68443 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null UT7 CCLE Cell Line Gene CNV Profiles -1.0 -1.32573 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE103068_0_v_4_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13377 GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.906322 outer CP in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.833286 GSE239844_4_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.29279 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3805 GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF417 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4244 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913904 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.878805 COLO-800 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.18353 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.94206 Anterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15025 DLX5_Deficiency_GDS4443_356_mouse_E10.5 embryos otic vesicle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Urinary system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE223893_1_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QLQ7-1526-SM-2S1QA GTEx Tissue Sample Gene Expression Profiles 1.0 0.873278 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12368 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.21708 CHEK1_knockdown_142_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.35613 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.1949 fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.70046 TCF3-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE147626_3_v_1_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93502 NTERA-2-cl-D1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.40183 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.10395 SARS-BatSRBD_0Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 3.53125 Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4921 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07792 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16359 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.870318 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE112760,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52356 CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.846728 ZNF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38243 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles -1.0 -1.07669 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE223893_2_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE211286_1_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE213228_1_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE162739_8_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07924 LC1SQ DepMap CRISPR Gene Dependency 1.0 2.75642 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01796 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41349 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3617 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13377 hsa-miR-4652-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04246 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BALL-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -5.37248 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01461 STAT3-1855785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.892093 BICR18 CCLE Cell Line Gene CNV Profiles 1.0 1.4304 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05102 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.79279 GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825612 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35665 Prenatal Injuries CTD Gene-Disease Associations 1.0 1.12254 Perturb_4540_KD_Bahd1_SRP126769 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.51377 ESR1-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null SQLE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02354 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.905214 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE202434,GSE202438_4_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHHCALL2 CCLE Cell Line Gene Expression Profiles 1.0 1.65761 SRC-2_Deficiency_GDS5087_270_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 GSE155031_5_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18329 Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zygotene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.905 BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE241701_2_v_3_daxx_mouse RummaGEO Gene Perturbation Signatures 1.0 null NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921994 mantle zone of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04027 mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24545 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.898495 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 0.904739 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.95777 GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.979269 GSE94849_6_v_2_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null FOXM1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199255,GSE199356_6_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null GSE187006_0_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5107 Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08733 COGN305 DepMap CRISPR Gene Dependency 1.0 2.38816 BICR22 CCLE Cell Line Gene CNV Profiles 1.0 2.31873 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PBX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU5F1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.26254 H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13377 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE142210_3_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.41379 TMA16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22661 Microtubule COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H2BK120ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17699_KO_Pds5a_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -17.1549 LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE199874_3_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anxiety Disorders CTD Gene-Disease Associations 1.0 1.46304 testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.445268 Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21875 NCIH650 DepMap CRISPR Gene Dependency 1.0 2.0303 ASH2L-23239880-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970395 GSE206270_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38211 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 2.42201 GTEX-RU72-1426-SM-46MUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.977312 ChIP_SETDB1_19884257 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057611 TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9893 GSE178714_3_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46383 GSE188458_2_v_4_hydrogen peroxide_human RummaGEO Drug Perturbation Signatures -1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.039205 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26697 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21495 GTEX-OIZI-0226-SM-2XCEE GTEx Tissue Sample Gene Expression Profiles 1.0 1.25008 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852231 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.964372 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.9162 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18142 E2F6 ENCODE Transcription Factor Targets 1.0 null Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48862 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null APP_KO_GDS4414_370_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26A-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MFM-223 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.593 GCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06079 Pachytene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.5265 TCFL5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.8579 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Female reproductive organ benign neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854833 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056492 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55185 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POYW-1226-SM-2XCEP GTEx Tissue Sample Gene Expression Profiles 1.0 0.824652 hsa-miR-1279 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30797 SK23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.83384 BHLHE40 ENCODE Transcription Factor Targets 1.0 null SBC-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.74131 r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04411 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles -1.0 -1.2528 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07728 CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HD-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862557 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08028 Uterine benign neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.830587 amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20661 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null karpas707 HPA Cell Line Gene Expression Profiles -1.0 -1.29602 GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902706 NFIC ENCODE Transcription Factor Targets 1.0 null MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885593 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.043 TCFL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24812 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP Rummagene Transcription Factor Associations 2026 1.0 null r9 portion of vagal motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42293 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE242290_1_v_8_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PVOW-0626-SM-2XCF6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.825113 Lateral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02378 sin3a_22783022_mcf7_lof_human_gpl570_gds4388 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.192249 Prostate carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.91694 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4729 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Urinary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.956969 SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.44862 GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles 1.0 0.984715 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8563805-41598_2021_858_MOESM2_ESM.xlsx-Supplementary_Info_6-Gene_List_6_The_list_of_human_orthologs_of_the_downregulated_fly_DEGs_identified_from_TRAP_control_vs_PARIS_wild_type_comparison_ZNF746 Rummagene Transcription Factor Associations 2026 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09047 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21358 SC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.57079 Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195559_0_v_9_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus of the solitary tract, gelatinous part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96521 GSE239578_5_v_6_cxadr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.04235 Scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.938 POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null IZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971648 IRF4 ENCODE Transcription Factor Targets 1.0 null urinary bladder HPA Tissue Protein Expression Profiles 1.0 0.855251 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61689 ascospore-type prospore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.528 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.11543 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MTA3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4964-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.38817 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87875 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05461 CEBPB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28378 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JHU022 DepMap CRISPR Gene Dependency 1.0 2.93301 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24621 GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 1.11208 496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.52056 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184892_7_v_2_trehalose_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null COX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12668 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.18657 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 JAR DepMap CRISPR Gene Dependency 1.0 2.76487 S100A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.059 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -1.3219 Myeloid neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.933206 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22144 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48751 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_4896_KD_NCBP1_SRP160510 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.4029 epididymis HPA Tissue Protein Expression Profiles 1.0 0.855251 MFE280 CCLE Cell Line Gene CNV Profiles 1.0 1.70869 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.457 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE113329,GSE113335_3_v_4_taf6l_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.37666 FBXO45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0833 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-548a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07375 TYK2_knockdown_176_GSE44652 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.2421 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.11578 CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82236 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24808 GTEX-WYVS-0526-SM-3NM9W GTEx Tissue Sample Gene Expression Profiles 1.0 1.06605 CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.3238 19837975-TableS1 GeneSigDB Published Gene Signatures 1.0 null GSE204811,GSE204813_1_v_3_trim29_human RummaGEO Gene Perturbation Signatures 1.0 null GSE103068_0_v_3_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XMK1-2226-SM-4B673 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24324 Meiotic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.021 THAP1_02_46 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.0 ventrolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.941909 GSE207611,GSE207612_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.06055 MCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46929 hsa-miR-3165 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11669 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2093 BCLAF1 ENCODE Transcription Factor Targets 1.0 null mRNA_RAD21_21589869 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63869 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.926173 POR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63622 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178714_6_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE188721_3_v_4_mesp1_human RummaGEO Gene Perturbation Signatures -1.0 null ChIP_ASH2L_23239880 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Uterine fibroid DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.578 perifornical nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878833 VMRCLCP CCLE Cell Line Gene CNV Profiles 1.0 1.5797 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178714_3_v_4_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE213410_2_v_3_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null BCL11A ENCODE Transcription Factor Targets 1.0 null KANSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00879 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57427 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.7358 hsa-miR-1252 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 CAL-39 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 ELK1 ENCODE Transcription Factor Targets 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97925 multiple myeloma GWASdb SNP-Disease Associations 1.0 1.48714 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86565 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15732 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null GTEX-S7SE-0926-SM-2XCD6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00019 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.34954 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5957 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null multiple myeloma GWASdb SNP-Phenotype Associations 1.0 1.32793 OXCT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52027 GSE213228_4_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4668-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 rh30 HPA Cell Line Gene Expression Profiles -1.0 -0.936779 r9 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53845 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051021 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0758 Autosomal dominant disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 SUPT5H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.1279 KYSE270 DepMap CRISPR Gene Dependency 1.0 8.92776 Cortical amygdalar area, posterior part, medial zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19097 female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060928 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null placenta_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.32392 H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE102505_1_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25958 GSE158834_1_v_8_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871407 hsa-miR-548b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45895 GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12843 POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03579 RPRML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03098 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE95077_5_v_4_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61684 GSE149901_3_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.75509 POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-1326-SM-4BOPQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.894075 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.77207 Thyroid nodule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.51 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835813 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA5_KO_GSE47425_50_mouse_lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE242290_3_v_8_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3365 NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.88889 GTEX-U8XE-1726-SM-4E3IF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88609 SP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199255,GSE199356_4_v_5_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD4-25478319-HGPS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2818 H3K27ac_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null TCF12_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC4 DepMap CRISPR Gene Dependency 1.0 3.28994 SUM52PE DepMap CRISPR Gene Dependency 1.0 2.30362 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_1_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13806 immune system cancer GWASdb SNP-Disease Associations 1.0 0.209765 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06958 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18185 CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955022 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.49756 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30913 MIA-PaCa-2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.25923 Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4587 Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9338 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r9 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38439 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCOA2_KO_GSE41558_19_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE131161_5_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE130437_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32402 striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09142 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62202 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null HCC95 CCLE Cell Line Gene CNV Profiles 1.0 1.6116 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27357 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.88136 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44868 LC-1-SQ COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 RTL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2098 Lung non-small cell carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 CBX3 ENCODE Transcription Factor Targets 1.0 null PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944326 POU2F2 ENCODE Transcription Factor Targets 1.0 null IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.35018 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3051 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.828986 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.19553 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9663 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69694 Interstitial lung disease 2 DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.95297 HCC70 DepMap CRISPR Gene Dependency 1.0 2.35414 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.19434 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916195 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05078 GSE158834_7_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.98431 Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04176 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14588 hsa-miR-4495 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 ZNF28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62288 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 1.83415 Box H/ACA snoRNP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.917 PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.09393 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.949696 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.70204 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130690,GSE130692_1_v_0_sirt6_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0768 IPC298 CCLE Cell Line Gene CNV Profiles -1.0 -2.4964 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thyroid cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.058 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23064 GSE158834_10_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SEMA3F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34435 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71465 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.337 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4463 Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TC-71 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06679 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7861 CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848669 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18551 periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14458 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.0852 CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26867 H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CPSF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92679 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71281 CAKI2 DepMap CRISPR Gene Dependency 1.0 2.4029 EAF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45623 Polymeric cytoskeletal fiber COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 hsa-miR-655 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 periventricular stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42829 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.4411 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUYS-0005-SM-47JZ2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0599 TRIM28 ENCODE Transcription Factor Targets 1.0 null ChIP_POU5F1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7692-01A-12R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.08464 GSE231891_5_v_4_cdk8_human RummaGEO Gene Perturbation Signatures 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00868 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67609 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRL-0226-SM-3NB18 GTEx Tissue Sample Gene Expression Profiles 1.0 0.855431 Rectum adenocarcinoma_READ_TCGA-F5-6811-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.91701 PTEN_01_301 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.9284 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94186 NCIH2172 CCLE Cell Line Gene CNV Profiles -1.0 -1.96425 H3K4me1_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE198165,GSE198166_5_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null r9 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45572 mRNA_NANOG_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PPARGC1A_NULL MUTATION_GDS2149_721_mouse_Brown adipocyte GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me1_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XGQ4-0926-SM-4AT4U GTEx Tissue Sample Gene Expression Profiles 1.0 0.977242 GSE198165,GSE198166_9_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAPK14_knockdown_139_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.99178 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975235 GSE220942_2_v_1_galnt7_human RummaGEO Gene Perturbation Signatures 1.0 null GSE143994_2_v_1_ythdf1_human RummaGEO Gene Perturbation Signatures 1.0 null ZIC5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.1996 GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06647 ASH2L ChEA Transcription Factor Targets 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 2.21591 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076564 GTEX-O5YV-1026-SM-3LK72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854927 Stratum germinativum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Autosomal genetic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 ChIP_TCF3_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MAP4K5_knockdown_199_GSE61497 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.81301 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55516 Perturb_15517_KD_E2F2_SRP314859 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.429 Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.167 skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.15767 Organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -2.14716 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.980365 primary auditory cortex (core)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42849 CHD2 ENCODE Transcription Factor Targets 1.0 null NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_8705_KD_SIRT1_SRP267968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.90117 RUNX3 ENCODE Transcription Factor Targets 1.0 null CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8342 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946566 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5321_KD_Stag1_SRP244261 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.39875 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A23B-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 780 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.952189 Chronic Lymphocytic Leukemia DisGeNET Gene-Disease Associations 1.0 null GSE162892_3_v_2_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12137 SRRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26165 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.24205 GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894078 GSE158834_1_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null RRP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32051 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845893 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null SRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07474 GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.41177 UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.23256 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195513_0_v_3_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00027 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null REH CCLE Cell Line Gene Expression Profiles 1.0 1.60278 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43562 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.977941 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33405 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3344 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60938 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.56129 Microtubule cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-576-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00811 Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.51667 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25554 DPY-21335234-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 GSE200673,GSE200691_2_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17245 GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Finding Of Mean Corpuscular Hemoglobin DisGeNET Gene-Phenotype Associations 1.0 null CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary ciliary dyskinesia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.399 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.09678 EC-GI-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Infralimbic area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29338 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44003 TCF3 ENCODE Transcription Factor Targets 1.0 null GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24355 GTEX-XUYS-0226-SM-47JX1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.82889 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 NR0B1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_9985_KD_U2AF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.01213 ERH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11025 SKHEP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.66021 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43352 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Organ system benign neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77976 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84559 CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SRC-2_KO_GDS5087_485_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937893 SR-786 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.966614 496100494_HIP_no dementia_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.80544 Perturb_14504_KO_Tgfb3_SRP020224 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.35569 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11743 CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5B ChEA Transcription Factor Targets 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 HPAFII DepMap CRISPR Gene Dependency 1.0 9.02865 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H2BK12ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE87615_2_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null MORCPR DepMap CRISPR Gene Dependency 1.0 2.18562 SOX2 ChEA Transcription Factor Targets 1.0 null POLR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30877 CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67297 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47967 CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null TM31 CCLE Cell Line Gene CNV Profiles -1.0 -1.66339 GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 1.01995 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null YLPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11197 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.43761 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00282 GSE175787_13_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null HCC44 DepMap CRISPR Gene Dependency 1.0 3.60488 GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03064 CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-180 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02234 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36016 PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3 Rummagene Transcription Factor Associations 2026 1.0 null ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8755 OCIMY5 DepMap CRISPR Gene Dependency 1.0 2.7154 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02118 POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884465 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PANC 05.04 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.923121 ZNF384 ENCODE Transcription Factor Targets 1.0 null PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP Rummagene Transcription Factor Associations 2026 1.0 null MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22297 mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46121 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.79076 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127970_2_v_3_ebf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null KAT2B_02_184 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61667 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53896 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.896 GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963978 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56307 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.86057 MYC_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13302 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null outer CP in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04693 TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 Central nervous system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.167 r9 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03989 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.18004 Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.74671 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.56804 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93244 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34864 MAFA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0623 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921994 Prospore membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.53 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE103068_5_v_7_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.395331 Perturb_11698_KO_METTL3_SRP287496 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.1872 Glutathione hydrolase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.953 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.993737 Bladder cancer GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.830103 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9026 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.744607 GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891924 Systemic Scleroderma DisGeNET Gene-Disease Associations 1.0 null Perturb_5058_KD_Crebbp_SRP225823 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.4822 PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null LSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44132 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_GADD45A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848208 Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-02A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas HPA Tissue Protein Expression Profiles 1.0 0.855251 FOXM1 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36873 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07615 hsa-miR-548j TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Congenital Abnormalities CTD Gene-Disease Associations 1.0 1.22048 Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.421 Brain Lower Grade Glioma_LGG_TCGA-FG-7634-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75983 GSE131161_3_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19259 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.846657 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD1-26771354-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886376 NoRC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.968 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.896962 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03267 GSE231720,GSE231724_2_v_0_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H3122 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.08826 HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.883848 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945428 GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.29625 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.50923 hsa-miR-548h TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 EPHB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16776 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.968614 GSE203308_7_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80648 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6111 COPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02731 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40712 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.866675 GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67259 r7 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0275 GSE178714_5_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Placenta TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11476 GSE229468,GSE229471_0_v_3_znf587_human RummaGEO Gene Perturbation Signatures -1.0 null somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.647316 PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.17721 mRNA_SOX2_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.13113 Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.849813 TE-6 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52804 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.939155 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.50448 GSE178532_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE103068_5_v_3_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202825_2_v_1_ano1_human RummaGEO Gene Perturbation Signatures -1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.874279 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12009 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919547 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.39832 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.48778 GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 KP-N-YS COSMIC Cell Line Gene Mutation Profiles 1.0 null ATP6V1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16424 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.63447 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Idiopathic interstitial pneumonia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 GSE226091,GSE226092_3_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Testicular somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.83 PHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0079 PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-548ak TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE158834_10_v_3_palm_human RummaGEO Gene Perturbation Signatures 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null Thyroid cancer GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12785 16293578-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8489 H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE231745_1_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures -1.0 null CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-175 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.97714 GSE146894_3_v_8_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null NFATC1 ENCODE Transcription Factor Targets 1.0 null GSE107956,GSE107957_0_v_1_ythdf2_human RummaGEO Gene Perturbation Signatures -1.0 null outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15251 GSE125219,GSE125221_3_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IH-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TAL1_02_201 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.1964 periventricular stratum of r8Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44672 RBBP5 ENCODE Transcription Factor Targets 1.0 null PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12582 PRR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67193 outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.92697 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW579 DepMap CRISPR Gene Dependency 1.0 3.32172 superficial stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.71582 H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03541 UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880841 GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles 1.0 0.845632 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.925645 IZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950549 inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.90328 SP1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.39625 GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53603 GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17880687-TableS3 GeneSigDB Published Gene Signatures 1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24298 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE171401_1_v_0_adnp_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE147876,GSE147877_4_v_11_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null 496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.50459 GSE122067_3_v_0_mtch2_mouse RummaGEO Gene Perturbation Signatures -1.0 null USP37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14418 GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96424 Perturb_15418_OE_KDM4B_SRP194543 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.4373 r9 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59737 H3K4me1_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20386 Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.47426 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.91694 GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2619 Perturb_5192_KO_Nanog_SRP116119 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.27073 GSE199255,GSE199356_4_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140937,GSE140938_0_v_2_slfn11_human RummaGEO Gene Perturbation Signatures -1.0 null SULT2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15709 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.845297 GSE103068_5_v_4_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null BATF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE95077_1_v_0_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null ChIP_SOX2_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.957427 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45858 CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE153137,GSE153140_2_v_0_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null BRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21754 GSE149035_2_v_5_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13355 medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12759 GTEx Colon 20-29 vs 70-79 GTEx Tissue-Specific Aging Signatures 1.0 7.74254 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-223 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1196 IZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907009 cellular_component GO Cellular Component Annotations 2015 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null chromosome, telomeric region COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.739 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922029 GTEX-XOTO-0826-SM-4B65O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906679 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75465 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03689 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1_DEPLETION_GDS3791_38_human_Hela GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18803 hsa-miR-513a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4 Rummagene Transcription Factor Associations 2026 1.0 null DU4475 DepMap CRISPR Gene Dependency 1.0 2.32194 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.75752 CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.870318 HEYA8 CCLE Cell Line Gene Expression Profiles 1.0 1.42862 BCL11A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Visual areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50239 CHD1-19587682-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null A388 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859497 KLF4-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TFG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44266 Perturb_13213_KO_Yap1_SRP059253 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.46987 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02292 GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.988396 alar part of peduncular hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00633 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06833 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF596 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33514 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE155800_1_v_0_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU1214 CCLE Cell Line Gene CNV Profiles 1.0 1.38694 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_POU5F1_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6675 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43505 GSE228106_0_v_4_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_NANOG_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.033 mRNA_SMARCA4_22196727 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ATF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LB771HNC DepMap CRISPR Gene Dependency 1.0 2.75005 GSE169152_5_v_6_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.0896 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07731 USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_13_v_7_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null ChIP_CHD1_19587682 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33465 EZH2 ENCODE Transcription Factor Targets 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RTLS-2426-SM-46MUO GTEx Tissue Sample Gene Expression Profiles 1.0 1.01719 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.16822 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.19682 PATU8902 DepMap CRISPR Gene Dependency 1.0 2.29161 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5336_KO_Myc/Mycn_ERP009787 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.62245 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.926139 HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (ventral) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57284 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE172189_0_v_1_venetoclax_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52348 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.916939 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36921 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63769 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10113 ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993235 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.348148 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.49217 CTU1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41963 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255567 primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865263 POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.51016 GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62839 ZIC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.1066 Perturb_17700_KO|KD_Pds5a|Pds5b_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 KNS-62 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 TXNDC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42198 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902197 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 1.25852 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.86257 HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-3R-A8YX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1897 CCLE Cell Line Gene CNV Profiles 1.0 1.51146 CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831496 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27011 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50309 GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05586 YY1 ENCODE Transcription Factor Targets 1.0 null Brain - Nucleus accumbens (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.686866 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles 1.0 0.93713 r8 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30682 BICR22 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GTEX-NFK9-1126-SM-3LK78 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839613 Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDAH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01111 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09807 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null CHD1 ChEA Transcription Factor Targets 1.0 null PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_ATF1-gene_ATF1 Rummagene Transcription Factor Associations 2026 1.0 null PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC Rummagene Transcription Factor Associations 2026 1.0 null Multiple myeloma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Endocrine system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.058 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80285 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8065 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861184 H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_1_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null HEB MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-XOTO-2126-SM-4B64U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.169 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921994 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.07949 posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02378 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828091 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LCLC103H DepMap CRISPR Gene Dependency 1.0 2.13732 Dorsal column nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08364 Small Lymphocytic Lymphoma DisGeNET Gene-Disease Associations 1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0435 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SOX3-22085726-MUSCLE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.47835 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.60314 GSE239844_7_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null Stargardt disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.038 LRRC8D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43495 ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.91233 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.70602 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.4568 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 1.0173 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3483 GSE226584,GSE226589_3_v_0_ezh2_human RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38498 ventrolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.26868 GSE147876,GSE147877_4_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30616 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SOX2-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ESRRB ChEA Transcription Factor Targets 1.0 null ELK1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-QDVJ-1326-SM-48U1X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.888978 PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521 Rummagene Transcription Factor Associations 2026 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09538 r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54701 GSE95077_5_v_2_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null KLF17 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.4489 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mpp10 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.696 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57604 Lung squamous cell carcinoma_LUSC_TCGA-56-7580-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1755 CCLE Cell Line Gene CNV Profiles -1.0 -1.52936 Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_11_v_3_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55E-0006-SM-2TC5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54062 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.46323 PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR Rummagene Transcription Factor Associations 2026 1.0 null PTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56414 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59398 ChIP_PRDM14_21183938 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4682 mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22902 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null OVCA433 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE195559_2_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08048 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE234340_3_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null LIN28B_01_153 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61989 r8 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4443 GSE207611,GSE207612_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null COLO 849 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.903278 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JHH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.92845 GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 0.883759 21205295-TableS1 GeneSigDB Published Gene Signatures 1.0 null KCNC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08389 HDAC2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-3908 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6887 GSE198165,GSE198166_5_v_11_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55358 hsa-miR-4528 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 POU2F2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936506 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_85_KD_CSN5_SRP316687 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.78778 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20935 BRCA1 ENCODE Transcription Factor Targets 1.0 null KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53738 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE48812_0_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06269 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null EGFR_druginhibition_82_GSE27638 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.35856 A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04217 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.990402 POU2F2_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1915 CCLE Cell Line Gene Expression Profiles 1.0 1.36558 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18168 BATF ENCODE Transcription Factor Targets 1.0 null hl60 HPA Cell Line Gene Expression Profiles 1.0 0.869565 CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM1A_KD_GDS5055_367_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null NFIC_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4554_KD_Mcrs1_SRP126769 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.52724 POU5F1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993697 disease GWASdb SNP-Disease Associations 1.0 0.038745 r8 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27625 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32124 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889729 Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVN-0826-SM-48TZ2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841999 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47662 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.846476 Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25475 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.844828 Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-944 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null HCC1428 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.02513 PML ENCODE Transcription Factor Targets 1.0 null MDAMB436 DepMap CRISPR Gene Dependency 1.0 2.43777 KLF4-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7823-01B-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hypoglossal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34744 REST ENCODE Transcription Factor Targets 1.0 null GTEX-QDT8-0011-R5A-SM-32PKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.09598 APLP2_KO_GDS4414_536_mouse_adult cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21844 CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.14781 CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.6745 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCS214 DepMap CRISPR Gene Dependency 1.0 2.37351 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6606 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WM278 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.16749 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.947 PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.859556 PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null BRCA1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null interstitial lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36161 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ESRRB-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null UCHL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03131 Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHMT2_KD_GSE34925_693_human_MDA-MB231 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2273 periventricular stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4515 orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12277 H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.656 REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Shelterin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.893 Cytoplasmic microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.158 IMR32 DepMap CRISPR Gene Dependency 1.0 2.45199 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28518 Sarcoma_SARC_TCGA-DX-A8BT-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.882686 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thyroid gland disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.058 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157635_1_v_0_trem2_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.74923 BUD23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87339 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48423 GSE164463_0_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFO-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.46932 H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.53862 POU5F1-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.941569 VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06044 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29287 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.31575 H3K27me3_iPS-20b Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Radial spoke head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.157 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.90936 fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.930577 GSE162739_4_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09015 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53323 rhombomere 10 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08881 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40594 Prostate cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986117 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66898 NCOR1-26117541-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE174498,GSE174500_2_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null Nucleus of the solitary tract, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00688 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_460_KD_CCR3_SRP220486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H2BK120ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UACC893 DepMap CRISPR Gene Dependency 1.0 2.2077 GTEX-X5EB-2426-SM-4E3HX GTEx Tissue Sample Gene Expression Profiles 1.0 0.863425 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18614 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE158834_11_v_8_palm_human RummaGEO Gene Perturbation Signatures 1.0 null BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07512 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SEC23IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19528 GSE147893,GSE147897_2_v_1_rbm4_human RummaGEO Gene Perturbation Signatures -1.0 null H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.881591 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE139427_2_v_1_ibrutinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46556 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 2.29242 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.19943 H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40648 Perturb_14731_KD_SUPT6H_SRP181929 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1176 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84614 Nervous system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.167 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.845252 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNRNP48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07268 Cell junction COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 Perturb_17702_KO|KD_Pds5a|Stag2_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.92827 PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67332 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.41246 hsa-miR-374c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 HDAC2_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine fibroid DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.148 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles 1.0 0.915555 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.064352 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.923541 GSE153137,GSE153140_2_v_1_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.830213 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17227 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.15199 Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42508 GSE242290_3_v_7_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null RAB40AL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4319 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.10497 Gracile nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9226 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37673 GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 0.947512 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13355 PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0665 GTEX-UTHO-1026-SM-3GAF7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.947382 posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.47849 GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00511 Supramolecular fiber COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41048 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE102505_6_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0541 GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13395 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22064 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77027 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861016 PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.8553 ventrolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.968594 Multiple myeloma and monoclonal gammopathy GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 GSE169334,GSE169336_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053392 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r9 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17276 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 R3HDM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54425 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.92549 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.36697 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.5806 MZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55639 Lymphoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.2249 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46507 fh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.004 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4460 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.710058 mRNA_POU5F1_16518401 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE216273,GSE216292_0_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE162739_7_v_1_bap1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.988736 dexamethasone_homo sapiens_gpl570_gse33135 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles 1.0 1.36413 Lung cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 WSB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39889 Eosinophil percentage of white cells GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.42218 GTEX-QDVJ-0726-SM-48U1W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02357 BV173 CCLE Cell Line Gene Expression Profiles 1.0 1.36065 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE198165,GSE198166_6_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_10_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null H3K4me1_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76202 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6992 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23683 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18956 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null placenta HPA Tissue Protein Expression Profiles 1.0 2.2449 TEAD4 ENCODE Transcription Factor Targets 1.0 null lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.10532 CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0264 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.4788 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.959847 ChIP_STAT3_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.462 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16873 GSE223893_1_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.888298 GSE178714_3_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null NCO2 CCLE Cell Line Gene Expression Profiles 1.0 2.54976 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ESR1_KD_GDS4061_453_human_MCF7 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Multiple Myeloma DisGeNET Gene-Disease Associations 1.0 null GSE113734_1_v_0_qprt_human RummaGEO Gene Perturbation Signatures -1.0 null JURKAT, CLONE E6-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14741 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924278 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0007 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-656 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Perturb_81_KD_CENPA1_SRP187530 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.36944 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.53031 Lateral terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.047 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.844828 CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.167 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GSE206270_1_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures 1.0 null MCUR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05938 LASV_FML29_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.49968 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.941569 SOX2-20726797-SW620-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH69 CCLE Cell Line Gene Expression Profiles 1.0 2.30338 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_17704_KO_Pds5b_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 amygdalohippocampal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41681 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.02809 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26352 Interstitial lung disease GWAS Catalog SNP-Phenotype Associations 1.0 0.718348 GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles 1.0 0.975193 CHD1 ENCODE Transcription Factor Targets 1.0 null pancreas GTEx Tissue Gene Expression Profiles -1.0 -0.915098 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 HTC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.598 NCIH2342 CCLE Cell Line Gene CNV Profiles 1.0 1.33964 NCI-H810 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.860049 Perturb_10701_OE_MIR20B_SRP309809 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE106170_1_v_0_nap1l3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07567 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null T47D CCLE Cell Line Gene CNV Profiles 1.0 1.36002 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02933 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null diagonal part of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02254 GTEX-T2IS-0226-SM-32QPH GTEx Tissue Sample Gene Expression Profiles 1.0 1.00034 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32979 fallopian tube HPA Tissue Protein Expression Profiles 1.0 2.2449 NO11 DepMap CRISPR Gene Dependency 1.0 7.35437 Reflex, Abnormal CTD Gene-Disease Associations 1.0 1.46304 Lung squamous cell carcinoma_LUSC_TCGA-39-5019-01A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null MIR222_KD_GDS4054_456_human_MCF7 breast cancer cells (fulvestrant-resistant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-RNOR-0326-SM-2TF51 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85238 Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74218 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47058 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.083344 GSE178714_6_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHAGO-K-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.923266 posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.886033 Lung adenocarcinoma_LUAD_TCGA-05-4415-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198165,GSE198166_6_v_3_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.68036 GSE87615_1_v_3_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.339 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE252857_1_v_0_klf15_mouse RummaGEO Gene Perturbation Signatures -1.0 null Outer dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.823 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178714_1_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null MYC ChEA Transcription Factor Targets 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-1226-SM-2S1Q9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962014 H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00272 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null respiratory system disease GWASdb SNP-Disease Associations 1.0 0.393491 Hindbrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53968 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37577 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.09978 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVUS-0011-R9A-SM-3GIJA GTEx Tissue Sample Gene Expression Profiles 1.0 1.02739 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20725 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34045 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LU-65 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98281 WRNIP1 ENCODE Transcription Factor Targets 1.0 null DB CCLE Cell Line Gene CNV Profiles -1.0 -2.20216 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 54.0191 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NAMALWA COSMIC Cell Line Gene Mutation Profiles 1.0 null mRNA_POU5F1_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11002 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.826164 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.239 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_SOX2_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39614 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20056 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060296 Nerve Degeneration CTD Gene-Disease Associations 1.0 1.02971 colonrectum_d HPA Tissue Sample Gene Expression Profiles -1.0 -0.962154 interstitial lung disease GWASdb SNP-Disease Associations 1.0 1.69911 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850782 H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE223893_4_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.970233 NANOG-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81833 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.883762 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ5-0626-SM-2I5F8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993634 r10 part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64156 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15638 Bone marrow cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00883 GTEX-R55G-0326-SM-48FDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09866 GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 0.899115 GSE173911,GSE173917_0_v_1_morc3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_1_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ECC4 DepMap CRISPR Gene Dependency 1.0 3.36456 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66349 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21038 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.50516 Ciliopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.534 Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE203308_14_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.89443 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26344 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.68194 H3K4me1_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TALL1 CCLE Cell Line Gene CNV Profiles -1.0 -1.52916 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03943 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41986 DYNLRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03039 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 769-P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21513 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916925 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178714_6_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null Immune system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Integumentary system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.967423 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71559 small-subunit processome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.908 496100472_PCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0253 posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0795 RH-18 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.45892 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQW-0326-SM-447A8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.989359 Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29338 Learning Disorders CTD Gene-Disease Associations 1.0 1.58654 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1821 GSE200687,GSE200688_1_v_0_sox15_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30692 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6997-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08103 GSE200099_3_v_1_honokiol_human RummaGEO Drug Perturbation Signatures 1.0 null HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100417_HIP_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20384 Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.12388 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null neoplasm GWASdb SNP-Phenotype Associations 1.0 0.079636 r10 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.71167 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin melanoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 hsa-miR-3121-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Supramolecular complex COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50558 496100571_FWM_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.04114 GSE216394_2_v_0_pfkp_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null TKKK DepMap CRISPR Gene Dependency 1.0 3.36802 periventricular stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02861 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8987207-DataSheet_1.xls-HEB_targets_Fig_2B-HEB_Activation_FC_1_5_ttest_0_05_shRNA_HEB_in_Jurkat_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCT4_KD_GDS1824_135_mouse_embryonic stem (ES) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RS411 CCLE Cell Line Gene Expression Profiles 1.0 1.48062 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73444 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RB1_KD_GSE50532_654_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Female reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983072 Acute Myeloid Leukemia_LAML_TCGA-AB-2844-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16467 HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.16881 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96331 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.936892 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924278 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.179 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15387 Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-0326-SM-4AT4M GTEx Tissue Sample Gene Expression Profiles 1.0 0.913053 Perturb_9516_Mut_Sall4_ERP111723 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.04496 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0499 496100592_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.72634 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39134 MELHO CCLE Cell Line Gene Expression Profiles 1.0 1.56085 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.931589 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.2866 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18565 OVCA-432 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.716 ATG101 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34368 GSE211286_7_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE130956_2_v_1_icaritin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.954441 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.850374 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856179 NIHOVCAR3 DepMap CRISPR Gene Dependency 1.0 3.46221 Liver hepatocellular carcinoma_LIHC_TCGA-HP-A5N0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00688 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-641 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NCI-H1568 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.55145 GSE122067_2_v_1_mtch2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF784 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5928 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.858162 EW8 DepMap CRISPR Gene Dependency 1.0 2.75529 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9 Rummagene Transcription Factor Associations 2026 1.0 null PMC11214527-mmc5.xlsx-ADNP-gene_ADNP Rummagene Transcription Factor Associations 2026 1.0 null CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178714_5_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null 18614019-TableS4a GeneSigDB Published Gene Signatures 1.0 null USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.836991 organ system cancer GWASdb SNP-Disease Associations 1.0 0.071193 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4749 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25353 Kidney disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29511 KNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.822 GSE158834_1_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23548 CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178714_3_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.40858 HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.87169 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 KLF4 ChEA Transcription Factor Targets 1.0 null GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.52464 RDES CCLE Cell Line Gene CNV Profiles -1.0 -1.76671 Mean corpuscular hemoglobin GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1699 inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.97635 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.929611 GSE196505,GSE196507_1_v_2_kdm2b_human RummaGEO Gene Perturbation Signatures -1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.847362 GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22224 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02748 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.25979 ARL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28174 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE98755,GSE98756_1_v_0_fbxl19_mouse RummaGEO Gene Perturbation Signatures -1.0 null PDK1_knockout_80_GSE26290 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.076913 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27564 Medullary reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02787 ventrolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29802 ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32866 Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.35484 organelle LOCATE Predicted Protein Localization Annotations 1.0 null POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL72 DepMap CRISPR Gene Dependency 1.0 2.23211 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.934661 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100586_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.69884 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01153 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SETDB1 ChEA Transcription Factor Targets 1.0 null NFE2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null D-392MG Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.03393 KMT2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14577 hsa-miR-578 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GSE234289_5_v_1_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-1826-SM-4AT6F GTEx Tissue Sample Gene Expression Profiles 1.0 0.908586 GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15056 H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0175 VEZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.444 NCOA2_KO_GDS5087_24_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99065 GSE223893_11_v_10_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null Benign neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE239578_0_v_4_cxadr_mouse RummaGEO Gene Perturbation Signatures -1.0 null MYL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29617 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null COLO684 DepMap CRISPR Gene Dependency 1.0 2.51798 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52281 GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.26838 OCIAML2 CCLE Cell Line Gene Expression Profiles 1.0 2.01379 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.11791 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Leukemia DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 paralemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29902 GSE120413,GSE120447_4_v_2_bap1_mouse RummaGEO Gene Perturbation Signatures 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127790_10_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54709 NRF1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE218060_7_v_6_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20198 CYBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54819 Interstitial lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.921362 POLR2A ENCODE Transcription Factor Targets 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null MAPK14_knockout_13_GDS2693 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.33103 periventricular stratum of r7Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05787 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BCL11A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49114 RXRA ENCODE Transcription Factor Targets 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31238 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_17701_KO|KD_Pds5a|Stag1_SRP365503 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.65252 GTEX-T8EM-0826-SM-4DM76 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835891 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.897157 periventricular stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.0224 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0501 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.716516 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906723 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null NFKB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6117 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18446 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Esophagus - Mucosa GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.637621 PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 hsa-miR-548w TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.39342 Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hmgn1_KO_GDS5010_407_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7308 ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.980043 GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.899469 GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13946 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3647-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 SNU503 CCLE Cell Line Gene CNV Profiles 1.0 1.49538 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34431 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.60327 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.64981 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.866329 FOXQ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51893 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21513 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.31331 GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925952 GTF2F1 ENCODE Transcription Factor Targets 1.0 null NCIH1734 CCLE Cell Line Gene CNV Profiles 1.0 1.87964 CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09089 IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40813 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 RFX7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5372 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.25733 ITGAV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07963 GSE198165,GSE198166_0_v_1_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null 639V CCLE Cell Line Gene Expression Profiles 1.0 1.42271 JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Interstitial lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 GSE144115_2_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.296 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.898932 FARAGE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.935966 Anterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14722 GSE178714_1_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null PMC4742856-srep20328-s7.xls-Sheet2-ZF_converted_to_Human_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.957545 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00282 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06445 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_10_v_6_palm_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leukocyte disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.99195 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 GSE198165,GSE198166_5_v_10_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSU DepMap CRISPR Gene Dependency 1.0 3.67032 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.59088 Parasolitary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61148 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53896 GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0655 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.9221 GTEX-QDT8-0226-SM-32PL4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.906644 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34126 GTEX-QMR6-0011-R2A-SM-32PKV GTEx Tissue Sample Gene Expression Profiles 1.0 1.37294 GSE179880_7_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures -1.0 null SOX2-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Axonemal microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.516 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.265 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16294 superficial stratum of r9Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59309 MLL3/4 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.737 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE112762,GSE112767_2_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.35238 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5042 PMC4728380-ncomms10153-s11.xlsx-Seitz_Burkitt-SEITZ_MYC_TARGETS_BURKITT_MYC Rummagene Transcription Factor Associations 2026 1.0 null H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07478 RPS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16154 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.91965 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924278 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71857 GSE138863_3_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-U3ZG-0001-SM-47JYF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01138 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.46018 SUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05884 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20038 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-323-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 RING1B-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Hmgn1_KO_GDS5010_405_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.866354 GSE199874_4_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null JUND ENCODE Transcription Factor Targets 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08598 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 MAF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2253 POU5F1-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ChIP_NR0B1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.65067 Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.468 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PTPN1_KD_GSE54157_673_human_KM-H2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 0.876 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3537 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MDAMB436 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.901642 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null Buffy coat cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.695 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RTLS-1326-SM-46MUN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66619 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 GTEX-SE5C-1226-SM-4BRWV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21493 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34909 HLF CCLE Cell Line Gene CNV Profiles -1.0 -1.44828 gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.41848 superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04451 EKVX CCLE Cell Line Gene CNV Profiles -1.0 -1.49941 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55787 GTEX-WY7C-2426-SM-3NB2V GTEx Tissue Sample Gene Expression Profiles 1.0 0.935294 ASH2L-23239880-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.0561 SKCO1 CCLE Cell Line Gene CNV Profiles 1.0 1.38093 nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.971564 Mitotic arrest phase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55327 GSE226091,GSE226092_0_v_1_sall1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.2825 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5X1-1426-SM-3GIKH GTEx Tissue Sample Gene Expression Profiles 1.0 0.99058 CNOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75607 Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.222 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842549 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824125 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KASUMI6 CCLE Cell Line Gene Expression Profiles 1.0 1.41074 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ESRRB_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31322 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.850374 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 1.01024 Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3182 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_NIPBL_20720539 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.949453 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.50413 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7993 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3356 Brain stem TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15329 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.86748 GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91597 GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.939377 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-466 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE147876,GSE147877_4_v_10_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null LZIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82719 GTEX-OXRN-1726-SM-3NM9B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14737 GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures -1.0 null GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null EW-18 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.98753 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24608 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07687 hsa-miR-548i TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR Rummagene Transcription Factor Associations 2026 1.0 null rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.875309 USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.29635 Box H/ACA RNP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.722 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.22798 GSE107505_3_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07512 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29699 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 C8166 DepMap CRISPR Gene Dependency 1.0 4.66598 septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878262 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.986536 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29484 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central gray substance of midbrain, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.933303 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70724 r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15796 GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.924083 GSE199255,GSE199356_3_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140936,GSE140938_0_v_1_slfn11_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.959308 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.24576 GSE140997_2_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.9161 H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13355 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.33191 GSE84922,GSE84924_0_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures 1.0 null 15297395-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null OCIM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.95735 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1359 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921994 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548n TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 CMAH_KO_GDS4770_420_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null gallbladder HPA Tissue Protein Expression Profiles 1.0 0.855251 hsa-miR-216b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 1.80445 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.760156 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.36226 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.46644 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE199255,GSE199356_3_v_2_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 0.855251 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91752 ZNF395 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62252 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 2.1622 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null A3-KAW COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_02_40 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.87447 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null A375 CCLE Cell Line Gene CNV Profiles -1.0 -1.391 Liver Diseases CTD Gene-Disease Associations 1.0 1.07625 Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.218 GSE195568_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00282 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69042 LS-513 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.66019 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68118 NR0B1 ChEA Transcription Factor Targets 1.0 null GSE102505_5_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYM-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.06729 hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.23286 GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 0.963639 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.42948 CAL-85-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GSE213228_2_v_0_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null USF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 2.12872 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31589 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.61069 SNU1033 DepMap CRISPR Gene Dependency 1.0 3.6755 EBF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5584-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.85501 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13076 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.31907 GSE206870,GSE206872_3_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE241701_4_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null SOHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2494 hematologic cancer GWASdb SNP-Disease Associations 1.0 0.209765 USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03882 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SUV39H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59096 LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.935966 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE231720,GSE231724_2_v_1_setd2_human RummaGEO Gene Perturbation Signatures -1.0 null Fog2_KO_GDS3659_152_mouse_adult heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.91845 GSE133516_0_v_6_kat7_human RummaGEO Gene Perturbation Signatures -1.0 null RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.3139 CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, upper limb, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05227 GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35084 PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TMMY-1326-SM-4DXU9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11886 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFATC1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-x_TFEB_KOcon_VS_WTcon_UP_TFEB Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19891 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal motor nucleus of the vagus nerve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93726 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-548d-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 FEZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33799 GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837391 Necrosis CTD Gene-Disease Associations 1.0 1.51911 NCIH146 CCLE Cell Line Gene Expression Profiles 1.0 2.32487 MYC-22102868-BL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01789 PPME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44739 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58735 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TP63 ChEA Transcription Factor Targets 1.0 null r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04872 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30608 Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZCRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38369 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF707 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.4944 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.2438 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.8037 H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Tegmental reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07459 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30734 496100476_TCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05789 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.38071 Brain Lower Grade Glioma_LGG_TCGA-HT-7676-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.882065 BFTC-905 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.79206 GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10615 H3K27ac_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33083 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p2 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30241 hsa-miR-4782-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.7874 GSE234647_1_v_3_regorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 0.85051 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TML8-1226-SM-32QON GTEx Tissue Sample Gene Expression Profiles 1.0 0.863098 GSE127790_4_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4898 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4749 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69723 TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thyroid gland carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.058 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 1.04479 GSE185922_1_v_2_riok2_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.465 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.87485 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 0.926645 KLF4-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.68369 HOXD9_01_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59765 MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.931774 AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53 Rummagene Transcription Factor Associations 2026 1.0 null LRRC8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06229 CFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33155 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37023 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18232 FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 2.02363 H2BK20ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3787 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26594 Perturb_17269_KO_Rfx2_SRP066176 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.5516 AKT1_OE_GDS2308_508_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE230263,GSE230265_0_v_1_runx1_human RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-EZ-7264-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_ESRRB_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Hematologic cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.96931 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 SOX2-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null EHMT2_KD_GDS4800_315_human_MDA-MB231 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Perturb_7824_KD_EWSR1_SRP106906 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.177 GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5322_KD_Stag1_SRP244261 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.12482 GSE174498,GSE174500_5_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27472 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.458 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE122215,GSE122217_0_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE164521_0_v_1_nitric oxide_mouse RummaGEO Drug Perturbation Signatures -1.0 null Lymphatic system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31203 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.953137 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0926-SM-32PL2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879634 Subcommissural organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.33719 Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.663 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.824477 GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.00345 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36836 CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.76983 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GOSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05725 OVKATE CCLE Cell Line Gene CNV Profiles 1.0 1.48991 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997433 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.21568 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03404 PA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.869871 r9 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02141 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.76737 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00051 liver GTEx Tissue Gene Expression Profiles -1.0 -1.45869 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23491 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.826684 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21277 Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45147 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0005 VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14698 STAT3-1855785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.869218 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051378 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.27315 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_KLF4_19030024 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TMEM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40794 Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2955 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32963 GTEX-VJYA-0726-SM-4KL1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903493 MYC-22102868-BL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Uterine disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24286 Meiotic cohesin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 Fetal Kidney Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.961355 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887413 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.65203 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.20935 non-secretory myeloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00178 MAZ ENCODE Transcription Factor Targets 1.0 null A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39884 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13355 hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.270003 ZNF549 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.6422 GSE178714_5_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11382_KD_NKX25_SRP152523 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.30291 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 Nodulus (X), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26545 ESRRB-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.09068 GSE195568_3_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.534 Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45496 PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08002 GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910082 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053606 lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.901326 Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 1.23104 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA Rummagene Transcription Factor Associations 2026 1.0 null CHL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67482 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid leukemia DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.923402 Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A6B7-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20634 STAT5A ENCODE Transcription Factor Targets 1.0 null PIP4K2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28491 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054606 Multiple myeloma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 GSE240386,GSE242143_1_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.887047 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.123 MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130081,GSE130082_5_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MADD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17541 SNU886 DepMap CRISPR Gene Dependency 1.0 2.73519 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93716 Mean corpuscular volume GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.02218 mRNA_TBX3_16767105 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null LC1F CCLE Cell Line Gene CNV Profiles 1.0 1.96867 Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.62648 STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22748 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.44887 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09009 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00545 Perturb_9221_KO_Scgn_SRP396836 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.35596 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15658 tobacco use disorder GAD Gene-Disease Associations 1.0 null NANOG-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.244 MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09545 TBP ENCODE Transcription Factor Targets 1.0 null EPAS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7359 SIN3A ENCODE Transcription Factor Targets 1.0 null Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.124 HS936T CCLE Cell Line Gene Expression Profiles 1.0 1.36114 mRNA_SALL4_19060217 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.25557 GSE223893_11_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34132 MCC142 DepMap CRISPR Gene Dependency 1.0 2.52508 CHD1-19587682-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Multiple sclerosis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0699 MYC_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.89647 Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Aortic endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.663 HIC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7802 WM2664 DepMap CRISPR Gene Dependency 1.0 3.58776 layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46382 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34346 PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE147366_3_v_2_med13_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.75726 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-567 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.899055 intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70295 CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S33H-0326-SM-4AD6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.845666 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02763 hsa-miR-200c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-PLZ6-1326-SM-3NB24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1479 ZNF416 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8725 GSE112762,GSE112767_2_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11481 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.16308 GSE234340_9_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MINK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01597 r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80648 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.50745 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.092376 SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.884727 Ciliated cell_Lung_Human CellMarker Gene-Cell Type Associations 1.0 null Chronic lymphocytic leukemia or multiple sclerosis GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.869897 NCIH2052 DepMap CRISPR Gene Dependency 1.0 5.28738 ZNF221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1869 Perturb_7444_KD_LOC550643_SRP096253 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.68868 GTEX-XMK1-1126-SM-4IHJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20744 H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05447 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.264353 H3K4me1_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE149035_1_v_5_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KNS42 DepMap CRISPR Gene Dependency 1.0 2.20975 MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.54297 FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NB10 DepMap CRISPR Gene Dependency 1.0 2.09791 GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.94642 PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00282 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.838536 CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04354 KDM4A ENCODE Transcription Factor Targets 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.15537 ZBTB14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0084 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.32148 GSE127790_9_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cerebellum TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bone marrow disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 hel HPA Cell Line Gene Expression Profiles 1.0 0.847493 GSE137325_2_v_0_copanlisib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null septum (resp epith) BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868467 liminal part of the r9 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04027 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18582 outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3662 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7694 primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.88889 MGST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16171 Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AKT1_knockdown_141_GSE31912 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.25345 lung disease GWASdb SNP-Disease Associations 1.0 0.415878 Reproductive organ benign neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.54 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_11_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null duodenum_4b HPA Tissue Sample Gene Expression Profiles -1.0 -1.37463 Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4897 IFT22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49655 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1737 GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869927 Metencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUPT4 DepMap CRISPR Gene Dependency 1.0 4.29665 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thyroid Carcinoma DisGeNET Gene-Disease Associations 1.0 null Perturb_8798_OE_HOTAIR_SRP352837 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.61099 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.25416 CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD1 ChEA Transcription Factor Targets 1.0 null GLIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.787 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CACUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53047 Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3951 TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2853-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH23 CCLE Cell Line Gene CNV Profiles -1.0 -3.18709 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55379 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE6 CCLE Cell Line Gene CNV Profiles 1.0 1.49647 GSE252857_1_v_0_prednisone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.35905 gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.03075 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.34292 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.06929 fallopian tube HPA Tissue Gene Expression Profiles 1.0 2.23111 CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.43782 Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63996 GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 1.02944 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.99448 GSE195663_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226091,GSE226092_0_v_4_sall1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78331 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00883 GSE112765,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null MLKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63683 GSE156923_2_v_1_rbmx_human RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27749 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83048 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13355 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.62208 Perturb_11441_KO_TP53_SRP253428 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.71713 GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 1.12934 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99266 ADAMTS16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7982 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20725 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72149 GSE103068_0_v_7_volasertib_human RummaGEO Drug Perturbation Signatures -1.0 null USF1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20386 Supramolecular polymer COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.584 PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null GSE223893_4_v_9_setd2_human RummaGEO Gene Perturbation Signatures 1.0 null Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.339 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles 1.0 1.14477 GSE216538_7_v_6_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55D-1426-SM-48FEN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40785 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 1.33181 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.87208 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.91561 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.65145 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08315 hippocampus (hippocampal formation)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.31521 GSE131161_1_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null JHUEM1 DepMap CRISPR Gene Dependency 1.0 8.02317 CHAGOK1 CCLE Cell Line Gene CNV Profiles 1.0 3.03561 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.871257 496100604_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.00088 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.81593 Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.835309 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.186 SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2022 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE175787_13_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13089 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 1.26465 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE175787_5_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6573 17616640-TableS1 GeneSigDB Published Gene Signatures 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BCLAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFKB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.8539 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.43657 MAX ENCODE Transcription Factor Targets 1.0 null r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04872 GSE160817_2_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7611 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70561 H3K9ac_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null SMAD1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNA polymerase transcription factor SL1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.898 GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles 1.0 1.02968 H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE248858_5_v_0_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.964061 DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37083 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.899303 RUNX1_01_159 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63968 GSE198165,GSE198166_6_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMS12BM CCLE Cell Line Gene Expression Profiles 1.0 1.68035 H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900321 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.840195 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11513 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.830587 DB DepMap CRISPR Gene Dependency 1.0 2.44084 SGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32608 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25359 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.03336 GSE140936,GSE140938_2_v_1_slfn11_human RummaGEO Gene Perturbation Signatures -1.0 null Monogenic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 PBX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE102505_6_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.17601 USF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE199538,GSE199539_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38099 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19929 Eosinophil percentage of granulocytes GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.4301 GSE161170,GSE161268_0_v_3_med1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.19926 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4945-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63405 H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12925 nasopharynx HPA Tissue Protein Expression Profiles 1.0 0.855251 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4479 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30941 POU5F1 ChEA Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A5RA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59537 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23171 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860868 Recombination nodule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.828 Perturb_8706_KD_SIRT1_SRP267968 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.1268 r4 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11508 TIA1_KO_GSE54418_267_mouse_spinal cord GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Atrophy CTD Gene-Disease Associations 1.0 1.31536 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.948019 periventricular stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5378 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Primary somatosensory area, lower limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31178 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1623 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-0826-SM-48TZN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836739 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04764 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03118 MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00133 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83242 pancreas_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.12045 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RAD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51034 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87925 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.49227 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ONS76 DepMap CRISPR Gene Dependency 1.0 2.04277 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.941569 NTF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04028 Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.56593 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-WFON-2126-SM-3LK7O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912698 CMAH_KO_GDS4200_114_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 1.11465 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15179 DGCR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67264 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86491 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06227 midbrain raphe nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01859 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.4231 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 NR0B1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Meiotic prophase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null GSE226316_0_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.8713 GSE186005_1_v_2_klf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null XY body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.912002 TUT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04976 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.12045 BMI1 ChEA Transcription Factor Targets 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE139540_0_v_2_menadione_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.51041 NFATC1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.21416 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13952 GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.996599 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.20662 GATA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81511 Telomere length GWAS Catalog SNP-Phenotype Associations 1.0 0.835701 TOLEDO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852231 RH28 DepMap CRISPR Gene Dependency 1.0 2.12757 SJCRH30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910746 hsa-miR-200b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GSE158834_10_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HEC108 CCLE Cell Line Gene CNV Profiles -1.0 -1.32108 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.81317 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27981 DOTC24510 DepMap CRISPR Gene Dependency 1.0 2.94858 Polysomal ribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.93 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4749 Lung adenocarcinoma_LUAD_TCGA-55-7907-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE160817_3_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE199538,GSE199539_2_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P4QS-1026-SM-3NMCW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878589 NCIH1105 CCLE Cell Line Gene Expression Profiles 1.0 1.80845 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4334 BMI1-19503595-MEFSC-MOUSE ChEA Transcription Factor Targets 2022 1.0 null G361 CCLE Cell Line Gene Expression Profiles 1.0 2.40267 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.21665 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884674 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null USF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11363 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55327 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null LC1SQSF CCLE Cell Line Gene CNV Profiles 1.0 2.4229 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.90801 Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 132.78 Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EI-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.293027 mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12802 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24947 Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.831 GSE144115_1_v_3_stag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890521 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66626 r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2469 Perturb_15574_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 17.4089 GSE150557_1_v_0_dnmt1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r7 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05787 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLAGL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.9824 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17569 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861538 CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.62745 Perturb_7595_KD_NSUN2_SRP384110 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.13342 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64088 GATA2 ENCODE Transcription Factor Targets 1.0 null GSE102505_5_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14138 GSE133505_5_v_4_myf6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.353 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33636 mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80396 brain HPA Tissue Gene Expression Profiles 1.0 0.923549 GSE198165,GSE198166_5_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_10_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 1.29134 GTEX-S7SE-0826-SM-4AT4D GTEx Tissue Sample Gene Expression Profiles 1.0 0.83198 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.951538 HS 294T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 GSE178714_1_v_0_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE165704_0_v_1_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU668 CCLE Cell Line Gene CNV Profiles -1.0 -1.32382 GSE147876,GSE147877_4_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01969 PACADD161 DepMap CRISPR Gene Dependency 1.0 2.51945 MGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14485 GTEX-VUSG-1226-SM-4KKZF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881295 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08716 496100593_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.39265 Cortical amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40667 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91336 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.801 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null periventricular stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6423 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null POLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03809 H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.25559 17880687-TableS2 GeneSigDB Published Gene Signatures 1.0 null hsa-miR-524-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Melanoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.27184 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.62425 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63782 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r10 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36873 GSE66014_0_v_1_perhexiline_human RummaGEO Drug Perturbation Signatures -1.0 null STAT3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_1_v_3_palm_human RummaGEO Gene Perturbation Signatures 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10929 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02355 SPI1_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835778 METTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75791 SOX2-20726797-SW620-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in rostral cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18627 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5055-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE201309_4_v_8_matrine_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.3349 G292CLONEA141B1 DepMap CRISPR Gene Dependency 1.0 2.6057 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null IRF4_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.899299 CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.23022 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_6_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null GBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33981 FAM86B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17476 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.833668 GSE162892_3_v_2_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22202 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1854 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.50397 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548ab TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 mantle zone of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02507 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD1-0011-R3B-SM-4AT5R GTEx Tissue Sample Gene Expression Profiles 1.0 0.882306 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null UPCISCC029A DepMap CRISPR Gene Dependency 1.0 2.36262 MTA3 ENCODE Transcription Factor Targets 1.0 null Perturb_2876_Mut_KRAS_SRP404927 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02874 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12247 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.43548 Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102132_2_v_1_irf3_human RummaGEO Gene Perturbation Signatures -1.0 null Hematopoietic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.858 Perturb_15634_KO_AHCY_SRP351305 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.60548 r9 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0058 Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216126 ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04862 Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1957 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.922276 hsa-miR-548y TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 CNOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10908 POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231891_1_v_0_cdk8_human RummaGEO Gene Perturbation Signatures 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.860933 ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TYK2_knockdown_35_GDS4754 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.2421 myeloma GWASdb SNP-Disease Associations 1.0 0.487532 NFE2 ENCODE Transcription Factor Targets 1.0 null r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64451 HDHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67461 RXRA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.1499 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_16_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S4Q7-0626-SM-4AD5M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08273 BCLAF1_01_214 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.84397 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE139348,GSE139349_1_v_0_dicer1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.38215 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69962 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.09549 Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 19549311-SuppTable2-MMLandPhenotype GeneSigDB Published Gene Signatures 1.0 null KCL-22 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.73669 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100583_PCx_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.17564 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.8149 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10435 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.11433 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE94849_6_v_4_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null Perturb_6578_KO_Zeb2_SRP066910 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Adenocarcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.68 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3351 GTEX-PWCY-0726-SM-48TCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08531 lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24787 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38409 GTEX-R55E-0011-R6A-SM-2TC5T GTEx Tissue Sample Gene Expression Profiles 1.0 0.939826 GSE126621,GSE126920_1_v_3_dppa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.900492 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nanog_KD_GDS1824_134_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Renal carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.086 GSE247764_0_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE198165,GSE198166_8_v_4_zfp266_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Nucleus of the solitary tract, commissural part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07459 GTEX-S341-0526-SM-4AD5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03633 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05947 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4331 nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70574 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08486 Mean spheric corpuscular volume GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.20969 skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -0.840707 GTEX-PX3G-0826-SM-48TZS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24034 EM2 CCLE Cell Line Gene Expression Profiles 1.0 1.51261 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05095 SK-ES-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875721 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835677 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.907622 CLDN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17266 MM1S DepMap CRISPR Gene Dependency 1.0 5.97797 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 NCI-H1304 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28378 Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48862 MAVER1 DepMap CRISPR Gene Dependency 1.0 2.14128 MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B5-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.935342 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13656 hsa-miR-4483 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.79178 Perturb_10198_KD_FIP1L1_SRP251753 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.988396 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7353 r10 part of vagal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45208 GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854131 Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-1326-SM-2XCFK GTEx Tissue Sample Gene Expression Profiles 1.0 0.910234 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA5_KO_GDS4809_170_mouse_Lung GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EOL1 DepMap CRISPR Gene Dependency 1.0 3.15646 PAX5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null esophagus_5c HPA Tissue Sample Gene Expression Profiles -1.0 -1.38494 GTEX-QEL4-1326-SM-447AD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846803 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8198 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880761 IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15062 TCF3-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.830395 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2465 GSE163297_0_v_2_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33636 GSE158834_1_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.986551 WBP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36262 TOV-112D Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.49735 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.950361 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 0.855251 Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1293 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.75737 GSE178714_1_v_4_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.936693 TF1 DepMap CRISPR Gene Dependency 1.0 2.83637 SK-CO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NANOG-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1734 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATP7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47822 p3 portion of the substantia nigra pars reticulata Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16747 POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38787 PMC12123029-41598_2025_3625_MOESM1_ESM.pdf-49-MEF2D_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30301 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.964963 HT55 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.44017 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.69708 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3292 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4894-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphatic system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.478 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07228 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3927 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25162 hsa-miR-520d-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 1.72215 SETDB1 ENCODE Transcription Factor Targets 1.0 null SETDB1-19884257-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9669639-mmc3.xlsx-NRLonly-degs-207-Single_cell_RNA-seq_differentially_expressed_genes_between_control_versus_USH1B_NRL_cells_NRL Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.926179 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.84981 CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11253 PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null outer CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22631 PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null HAUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22116 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42235 ATF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-0326-SM-48U15 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20531 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.07503 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.94149 MRPL57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33479 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05055 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE183041_1_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null liminal part of the r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38043 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE196671_5_v_1_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.0927 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles 1.0 0.839493 Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Posterior amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03913 NOS-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.32652 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06278 GSE193258,GSE193259_5_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null MBTPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08828 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052904 GSE102505_1_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null GSE127790_13_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.84539 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAPAN-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.24139 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46426 Perturb_11378_KD_OGT1_SRP311080 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.0342 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1691 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17842 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.853291 GSE135244_0_v_1_trdmt1_human RummaGEO Gene Perturbation Signatures 1.0 null CYB5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35051 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00303 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.21586 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13235 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.88278 ZNF263 ENCODE Transcription Factor Targets 1.0 null U2OS CCLE Cell Line Gene CNV Profiles -1.0 -1.64855 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.859129 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.36596 GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.45904 RFX5 ENCODE Transcription Factor Targets 1.0 null ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-1926-SM-4BOOK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908707 GSE148010,GSE148120_3_v_2_tet2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825849 POU2F2_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.42991 GTEX-XPVG-2726-SM-4B66W GTEx Tissue Sample Gene Expression Profiles 1.0 0.846998 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE211262,GSE211263_3_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_14788_OE_Slit2_SRP267596 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.39265 duodenum HPA Tissue Gene Expression Profiles -1.0 -1.07219 USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41835 molecular_function GO Molecular Function Annotations 2015 1.0 null GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11893 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7583-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null INCENP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57197 Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30423 GSE228106_0_v_5_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null CHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55379 H4K91ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ1-PC Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.37821 ChIP_NANOG_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16318 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9558 RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884674 GSE165174,GSE165175_0_v_1_trametinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null ANO8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05831 GTEX-S3XE-0926-SM-4AD4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.872924 Inner dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.883 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.921994 NCI-H322T Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.179 Multiple Sclerosis DisGeNET Gene-Disease Associations 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r10 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80396 EBF1 ENCODE Transcription Factor Targets 1.0 null CSTF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91629 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.69574 all GWASdb SNP-Phenotype Associations 1.0 0.048087 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.877863 TCF12 ENCODE Transcription Factor Targets 1.0 null ATF2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nanog_16518401_mesc_lof_mouse_gpl1261_gds1824 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.99533 KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 1.73333 CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10393 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_11_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE133516_5_v_3_kat7_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.93485 Perturb_9517_Mut_Sall4_ERP111723 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.13651 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.860441 CAKI-1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.56268 ZEB1 ENCODE Transcription Factor Targets 1.0 null SETDB1-19884257-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GSE124920_1_v_2_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE223241_1_v_3_cdkn2a_human RummaGEO Gene Perturbation Signatures -1.0 null mitochondrion LOCATE Predicted Protein Localization Annotations 1.0 null hsa-miR-4732-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE203308_6_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939544 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.13952 ZNF676 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38427