association dataset threshold value standardized value BRD-K71533707 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41508 succinylsulfathiazole-4265 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.77527 ciprofloxacin-6700 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29874 BRD-K69152679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32774 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GJA9 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0047851 BRD-K51054234 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.45836 BRD-K20009653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04241 GTEX-WYVS-2126-SM-3NMA3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51415 BRD-K05248348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75811 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 GTEX-UPK5-1626-SM-4JBHI GTEx Tissue Sample Gene Expression Profiles 1.0 1.21837 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13776 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.851518 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 Prostate adenocarcinoma_PRAD_TCGA-HC-8259-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.830113 NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31691 Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87967738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19925 alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.207912 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.55381 GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.970934 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YN-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K37721603 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40823 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.834931 Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21546432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02452 SNU-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.847551 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32307 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06514 BRD-K83872468 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.6631 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.95353 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.90122 NCIH2066 CCLE Cell Line Gene CNV Profiles 1.0 1.43985 GTEX-V1D1-1726-SM-4JBHB GTEx Tissue Sample Gene Expression Profiles 1.0 0.840566 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03369 GTEX-UPK5-1226-SM-4IHL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2987 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00618 BRD-K23817660 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24823 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889759 BRD-K03154735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03519 BRD-K13922961 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04994 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.76597 5707885-6390 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-T6MN-0011-R1A-SM-32QOY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54664 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.972727 HSF1_KD_GDS1733_754_human_HeLa cells - 0 Hour by siHSF1_2 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K90686530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01908 BRD-K02403042 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01668 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.34034 BRD-K78904317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20885 GTEX-OXRK-1626-SM-3NB17 GTEx Tissue Sample Gene Expression Profiles 1.0 0.843021 BRD-K65259629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27458 BRD-K58762810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63577 Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null deferoxamine-3760 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -2.0842 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.19873 minaprine-4230 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K48922193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44487 JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -1.62826 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-1726-SM-3DB79 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50651 BRD-K46913557 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54688 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 0.986581 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65371 Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K39863565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35532 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K16268355 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52193 GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99083 cyclopenthiazide-4229 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44717 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860757 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34536 OVCAR8 BioGPS Cell Line Gene Expression Profiles -1.0 -1.60707 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.063923 BRD-K28467592 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22908 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.891411 BRD-K68087668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03731 BRD-K62219570 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26162 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881198 GTEX-SNMC-1126-SM-4DM5M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83857 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898314 BRD-K24502602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32997 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.33595 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08155 BRD-K87447060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81201 IMR32 CCLE Cell Line Gene CNV Profiles 1.0 2.02476 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.85982 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5274 BRD-K35646839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07237 GTEX-PLZ5-0926-SM-3TW8L GTEx Tissue Sample Gene Expression Profiles 1.0 0.974804 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41559 BRD-K07029108 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13623 GTEX-PLZ6-0826-SM-3P61K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75636 Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78222058 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23341 BRD-K28733696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10296 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.76111 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K38446773 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04078 BRD-K00083518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48818 BRD-K02783902 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60722 BRD-K95877349 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.96022 GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960216 Sarcoma_SARC_TCGA-DX-A1L2-01A-22R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PX3G-0826-SM-48TZS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842276 Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K23405293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.08889 rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.95128 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.921726 Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K67390084 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06948 BRD-K10513366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10708 Brain Lower Grade Glioma_LGG_TCGA-FG-7637-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41062 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22521 Prostate adenocarcinoma_PRAD_TCGA-HC-7748-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22521 GCT CCLE Cell Line Gene CNV Profiles -1.0 -1.94831 GTEX-XQ8I-1326-SM-4BOPV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.623 GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832842 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41302 GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909601 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1476 BRD-K64571715 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35274 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.45015 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4163-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.24206 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35678 Prostate adenocarcinoma_PRAD_TCGA-HC-7230-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10886 GTEX-OOBK-0008-SM-3NB27 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.82807 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.17219 Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31187 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11908 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08873 GTEX-OXRL-0626-SM-3NM9C GTEx Tissue Sample Gene Expression Profiles 1.0 0.831297 BRD-K36197756 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.206 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38295 GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.24845 BRD-K49298555 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.62978 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEPACAM LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00486696 BRD-K50830147 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.00961 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.895976 Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02222 GTEX-OOBK-0625-SM-3LK5P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49664 GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08396 BRD-K94540403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20318 tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.20658 BRD-K54467766 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14254 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06588 BRD-K36764776 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58263 BRD-K50623282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16954 BRD-K09720842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68351 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12782 GTEX-S7SE-0526-SM-2XCD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.943094 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08162 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K08715020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25901 basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.02516 GTEX-OXRK-1326-SM-3NB1A GTEx Tissue Sample Gene Expression Profiles 1.0 1.0012 HOP92 BioGPS Cell Line Gene Expression Profiles -1.0 -1.40995 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84085 SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11881 GTEX-OOBK-1026-SM-48TC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 BRD-K49409947 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08599 Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931006 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7734-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.55381 Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K85059356 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18229 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27108 GTEX-U3ZH-0226-SM-3DB7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900704 BRD-K39185798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.162 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51982 BL41 CCLE Cell Line Gene CNV Profiles -1.0 -1.67108 BRD-K13804959 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25821 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.96739 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07269 BRD-K62584372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14243 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.911821 BRD-K29331543 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06062 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.879663 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06055 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TSPAN32 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00584974 GTEX-X585-1226-SM-46MW7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29722 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95717 BRD-K22062326 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.67902 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 1.91583 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.63594 GTEX-XQ8I-1826-SM-4BOOJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80432 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.933495 BRD-K39016838 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26759 Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-SNMC-0226-SM-4DM6F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36734 BRD-K03901181 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26262 GTEX-OXRL-2626-SM-2I3F1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.919785 GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07282 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01334 IGSF1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0051467 Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.888837 BRD-K06428422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.98902 GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902606 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ES-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.974382 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.18425 BRD-K61522760 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06089 GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16443 KMS-21BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.907945 GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.836399 BRD-K91397206 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16656 Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-POYW-0526-SM-2XCEY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944738 RYR2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00510353 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64973 LPA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00625382 BRD-K52372795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21533 BRD-K00231307 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59323 SUPT11 CCLE Cell Line Gene CNV Profiles 1.0 1.51211 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931006 GTEX-S7SF-0926-SM-4AD4M GTEx Tissue Sample Gene Expression Profiles 1.0 1.04423 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868127 BRD-K26582498 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.90158 GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99306 BRD-K79433629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06397 GTEX-PLZ6-0326-SM-3P61J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71105 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881198 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.45208 BRD-K87781745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47452 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLK2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00356808 GTEX-N7MT-0326-SM-48TDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.0033 BRD-K26809097 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05343 layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.930795 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.862105 0317956-0000-3777 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2073 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.865124 GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 1.25469 BRD-K16247913 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18374 BRD-K90879242 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63821 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 BRD-K90808566 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.2834 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74362 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00607 chlortetracycline-6761 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.91807 BRD-K82249895 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80641 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24301 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.63254 GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904584 GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11326 BRD-K06431655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64574 Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K07540687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59121 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.981418 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07754 GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14959 BRD-K49325049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.01944 lobelanidine-5080 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.39786 GTEX-OHPK-2526-SM-3MJH9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.940368 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.919457 SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.05159 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.903124 BRD-K63065496 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01854 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13097 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.833983 GTEX-SNMC-0526-SM-4DM69 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29289 GTEX-XBEW-1326-SM-4AT63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15022 BRD-K65427501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4115 GTEX-S4Q7-0626-SM-4AD5M GTEx Tissue Sample Gene Expression Profiles 1.0 0.856746 KRAS.AMP.LUNG_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15952 deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.58616 GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20467 GTEX-SNMC-1626-SM-4DM52 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29351 GTEX-XQ8I-0926-SM-4BOOF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.25931 Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K39176069 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30014 Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K26005379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56903 BRD-K09137343 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07528 SW780 CCLE Cell Line Gene CNV Profiles -1.0 -1.36911 GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02468 BRD-K32595757 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09536 miR-124_OE_GDS2657_771_human_HepG2 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null BRD-K97067262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.78254 BRD-K02240568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07653 BRD-K50240676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06635 Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.56308 BRD-K51934291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10522 BRD-K62833799 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.86579 Acute Myeloid Leukemia_LAML_TCGA-AB-2874-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5642 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944938 sulfachlorpyridazine-3769 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles 1.0 0.920531 GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869206 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24321 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09457 BRD-K11630986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81515 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.02424 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.172 BRD-K96353852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7774 BRD-K95192796 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29493 BRD-K07526417 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21368 BRD-K04559718 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.49122 CALU-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07805 BRD-K07798964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02317 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.28765 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02649 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.838287 GTEX-UPK5-2026-SM-4JBIM GTEx Tissue Sample Gene Expression Profiles 1.0 1.37709 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84093 BRD-K66954388 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.19838 BRD-K36168475 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11877 substantia nigra, pars compacta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10171 Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K31437957 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.19813 Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.86662 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null calycanthine-5744 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.14757 BRD-K48556518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12725 dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831622 learning disability DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.09125 BRD-K33462260 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07411 GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917524 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 CAL-12T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.867092 BRD-K32018176 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50131 BRD-K99609051 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33682 GTEX-TML8-1526-SM-4DXUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.22252 GTEX-SNOS-0626-SM-4DM5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.17564 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56486 BRD-K79152256 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03402 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30333 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77645 BRD-K15047839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47058 Prostate adenocarcinoma_PRAD_TCGA-HC-7075-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K44664883 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.46348 BRD-K90151990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23496 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31885 BRD-K07276022 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.21234 BRD-K54484272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68938 metamizole sodium-4310 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SKBR3 CCLE Cell Line Gene CNV Profiles -1.0 -1.36419 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.974972 GTEX-S4Z8-0526-SM-4AD4T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04442 BRD-K56661847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01326 BRD-K46715415 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06958 BRD-K35085740 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3973 BRD-K82244940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3377 BRD-K17020860 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25489 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.05836 GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0406 BRD-K96788889 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42507 GTEX-XQ8I-2026-SM-4BOOL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68256 GTEX-PW2O-0526-SM-2I3DX GTEx Tissue Sample Gene Expression Profiles 1.0 0.852152 Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K53186055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.3743 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26159 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.69724 GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18774 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null solasodine-4305 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-RWS6-0826-SM-47JXF GTEx Tissue Sample Gene Expression Profiles 1.0 1.14705 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 2.43074 BRD-K64296795 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42913 HUPT3 CCLE Cell Line Gene CNV Profiles 1.0 1.62356 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872473 BRD-K22390389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10395 NCIH647 CCLE Cell Line Gene CNV Profiles 1.0 1.71574 GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49586 GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.932201 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.69528 GTEX-SNMC-1526-SM-2XCFN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942633 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885434 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27872 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06001 BRD-K55478267 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10169 BRD-K69740275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1849 BRD-K27525139 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31835 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68278 BRD-K44814060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39957 BRD-K37269981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70144 BRD-K42526449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74474 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09071 GTEX-V955-1326-SM-4JBHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.933477 Lung squamous cell carcinoma_LUSC_TCGA-77-A5G3-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.99757 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979721 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q3-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.997679 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68069 BRD-K59130783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16081 BRD-K03911650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18771 Bipolar Disorder_frontal cortex_GSE5388 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.36711 GTEX-RWSA-1426-SM-47JXA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.984171 H2595 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924634 BRD-K99331869 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20945 heart GTEx Tissue Gene Expression Profiles -1.0 -0.842056 BRD-M01343043 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89357 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.49441 Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00056 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 3.08384 Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65371 BRD-K39498165 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.52558 BRD-K31836496 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.29914 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.14584 GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 BRD-K63909265 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12547 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.094 Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18101 BRD-K54495109 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.30015 BRD-K69751974 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01009 Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGR37 CCLE Cell Line Gene CNV Profiles -1.0 -1.89519 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 2.24782 profenamine-6697 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K74988798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13282 BRD-K09149805 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27491 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12997 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38495 GTEX-OOBJ-1626-SM-2I3F7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911337 GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845269 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.31354 semustine-7545 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XQ8I-0826-SM-4BOOE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36079 cefsulodin-4067 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02525 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57677 GTEX-OOBK-2025-SM-3LK5S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17505 BRD-K52339742 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64528 olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10749 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.899494 GTEX-S3XE-1026-SM-4AD4O GTEx Tissue Sample Gene Expression Profiles 1.0 1.02489 GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48057 Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84688359 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4792 cisplatin_homo sapiens_gpl570_gse23553 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K60751806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.192 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66298 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.71678 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62237 BRD-K03937692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12369 NCIH2342 CCLE Cell Line Gene CNV Profiles -1.0 -1.75693 Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K46623934 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1126 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22521 GTEX-XQ8I-0326-SM-4BOPN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.88146 Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K50941255 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05771 SF268 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02126 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.15646 PCI-15A COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.94499 BRD-K99172965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38339 BRD-K45589340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79188 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68826 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49184 GTEX-Q734-0526-SM-2I3EH GTEx Tissue Sample Gene Expression Profiles 1.0 0.925571 GTEX-XQ8I-0726-SM-4BOPU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14061 SP in entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89911 GTEX-WYVS-2426-SM-3NMA9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02702 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09877 BRD-A91891312 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31204 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03145 Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-1026-SM-4IHLT GTEx Tissue Sample Gene Expression Profiles 1.0 1.51784 Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.49779 GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.27718 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34986 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932117 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.46134 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.954541 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.853533 MFE319 CCLE Cell Line Gene CNV Profiles -1.0 -2.29007 BRD-K93153656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37888 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.348 BRD-K24479270 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43308 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOUNH91 CCLE Cell Line Gene CNV Profiles -1.0 -1.57855 GTEX-X3Y1-0626-SM-3P5YS GTEx Tissue Sample Gene Expression Profiles 1.0 0.996227 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22521 BRD-K79748783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.60723 Lung adenocarcinoma_LUAD_TCGA-MP-A4TH-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cetirizine-4231 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K61560971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.89503 BRD-K58888361 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03245 BRD-K49050984 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32059 Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.901497 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26487 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XYKS-1526-SM-4BRUP GTEx Tissue Sample Gene Expression Profiles 1.0 1.07653 BRD-K03344897 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04281 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17427 zuclopenthixol-4261 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.947247 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J3-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99736408 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00423 BRD-K79829201 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68711 progressive supranuclear palsy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.00668 GTEX-QV44-0926-SM-2S1RH GTEx Tissue Sample Gene Expression Profiles 1.0 0.921622 GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 1.00868 GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.95479 GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38058 GTEX-U3ZH-0326-SM-3DB7A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.94821 BRD-K47113219 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12573 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.971459 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10651 BRD-K84388444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19239 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13051 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7404-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.49844 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47164 GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 1.58567 HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932117 BRD-K23694339 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.63213 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.854789 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K21125528 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55504 BRD-K69175109 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46356 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.852822 BRD-K29842194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35562 PHA-00851261E-3773 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K14538540 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10886 GTEX-XQ8I-1526-SM-4BOOH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80146 BRD-K24946605 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22446 GTEX-NFK9-1126-SM-3LK78 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54776 BRD-K94439911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50407 Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 2.19528 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 BRD-K96737756 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30235 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98142 BRD-K40300525 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21576 OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.16927 GTEX-WYVS-1726-SM-3NMAY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 A2058 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862507 EWSR1 ChEA Transcription Factor Targets 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.987137 ZR75_1 BioGPS Cell Line Gene Expression Profiles 1.0 1.2701 estradiol-4465 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-T6MN-0426-SM-32PMF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2888 BRD-K31952722 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19646 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-OOBK-0526-SM-2HMJJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961716 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.914124 BRD-K68328788 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09593 GTEX-PLZ6-1326-SM-3NB24 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80003 BRD-K54785691 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79144 Fetallung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -3.02561 U118 BioGPS Cell Line Gene Expression Profiles -1.0 -1.12278 BRD-K79213964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58607 16-phenyltetranorprostaglandin E2-7546 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A5KF-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K29144638 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21128 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46171 GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.975939 GTEX-SJXC-2026-SM-4DM6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.969213 GTEX-OOBK-0425-SM-3LK5O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42494 BRD-K50146114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4932 fluoxetine-6757 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XQ8I-0526-SM-4BOPS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42857 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42869 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01076 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75063 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904363 GTEX-R3RS-1326-SM-48FE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27548 BRD-K50423606 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42069 BRD-K32208085 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1881 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.842779 BRD-K73859343 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32622 AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37736 phenylpropanolamine-6699 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.77666 BRD-K26395018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2326 ampyrone-4507 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.967577 BRD-K82683018 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.02377 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03547 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.08056 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.07336 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.61153 GTEX-WFG7-1826-SM-3GIL1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.892156 GTEX-XUYS-0005-SM-47JZ2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85715 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.970519 Lung squamous cell carcinoma_LUSC_TCGA-58-A46K-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1016 BRD-K51167279 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35187 GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.968053 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13751 NUGC4 CCLE Cell Line Gene CNV Profiles 1.0 2.16843 GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914196 BRD-K37029442 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55831 cyclobenzaprine-4252 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03575 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05169 BRD-K22002184 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.33247 parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.348614 GTEX-R3RS-0726-SM-3GIJR GTEx Tissue Sample Gene Expression Profiles 1.0 0.829283 BRD-K29441085 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33048 BRD-K21176869 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10765 OVCAR3 BioGPS Cell Line Gene Expression Profiles 1.0 0.934854 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24161 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858026 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A24714998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14679 CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.855498 Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.51113 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null promazine-4308 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.868127 BRD-K48880196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38663 TEN CCLE Cell Line Gene CNV Profiles 1.0 1.46875 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K28108927 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44154 DMS-273 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03535 BRD-K25408656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04957 BRD-K91426044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39391 GTEX-PLZ6-0926-SM-3P5ZQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46683 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 BRD-K50247051 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40417 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K12578029 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03384 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.42185 GTEX-SUCS-0726-SM-4DM7J GTEx Tissue Sample Gene Expression Profiles 1.0 1.13015 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56239 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.60337 BRD-K60306319 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03414 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.13789 GTEX-QDVJ-0226-SM-2I5FV GTEx Tissue Sample Gene Expression Profiles 1.0 0.955158 BRD-K97962579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44643 BRD-K26709432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2671 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34986 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-1826-SM-4E3K8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.880935 BRD-K78262424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53536 GTEX-U3ZH-2026-SM-3DB78 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60596 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41106 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.925541 GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 2.11383 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.29785 BRD-K76966915 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1439 BRD-K76609014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06118 BRD-K39859838 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03058 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08204 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73196 BRD-K10157835 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.5625 BRD-K92776249 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35504 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28962 pancuronium bromide-4570 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.46287 BRD-K45952474 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4921 GTEX-WFJO-0926-SM-4LVM2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.861492 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7368-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.930974 Wholebrain BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.54437 GTEX-V1D1-1026-SM-4JBHE GTEx Tissue Sample Gene Expression Profiles 1.0 1.3117 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.21743 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.1505 BRD-K14181473 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24516 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67971 BRD-K27147269 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59985 GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861095 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51211 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962543 BRD-K89638177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26296 hydrastinine-5075 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null monorden-484 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null basal ganglia disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.318635 GTEX-WYVS-2526-SM-3NMAT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2577 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99847716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03907 BRD-K56301498 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15029 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64298 GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30788 BRD-K31977946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.95389 GTEX-XQ3S-2526-SM-4BOOG GTEx Tissue Sample Gene Expression Profiles 1.0 0.838653 GTEX-WOFM-1326-SM-3MJFR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.991787 GTEX-OOBJ-2026-SM-3NB1R GTEx Tissue Sample Gene Expression Profiles 1.0 1.17817 BRD-K98545272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16957 BRD-K79103937 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29436 BRD-K98249237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.06147 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59128 BRD-K85513726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00866 Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A97N-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K43624274 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49508 pirinixic acid-464 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SARS-BatSRBD_72Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.38124 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50901 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paclitaxel_homo sapiens_gpl570_gse39042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09591 scoulerine-5111 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K37722313 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64343 CP67-MEL COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 BRD-K46152990 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.91027 famprofazone-4309 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K64751430 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42898 GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.66768 JURKAT, CLONE E6-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.919579 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.905874 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOU-NH91 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.978022 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.979721 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.34513 miR-124_OE_GDS2657_770_human_HepG2 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33496 BRD-K74611044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1128 BRD-K04877446 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45167 ranitidine-2088 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.30332 GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.969243 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K70876639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59536 GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32118 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28188 BRD-K69241192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.87905 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4894-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.341 BRD-K03861440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57782 GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5964 GTEX-XK95-0008-SM-4AT5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09798 Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-Q2AH-0826-SM-48TZN GTEx Tissue Sample Gene Expression Profiles 1.0 0.935629 KCIMOH1 CCLE Cell Line Gene CNV Profiles -1.0 -1.42876 Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06044 Prostate adenocarcinoma_PRAD_TCGA-YL-A9WJ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.98707 BRD-K33710385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73234 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862903 GTEX-XQ8I-0226-SM-4BOPM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-U3ZH-1626-SM-3DB74 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28273 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.86713 Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TKQ1-0326-SM-4DXSM GTEx Tissue Sample Gene Expression Profiles 1.0 0.997881 GTEX-PLZ6-1126-SM-3P5ZR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24635 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K50127933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.73533 torasemide-5057 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K25484053 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85598 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.1014 BRD-K50859531 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10262 BRD-K38574421 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83829 EWS-ERG-20517297-CADO-ES1-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15666 BRD-K13672060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.60669 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YW-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K10325583 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07275 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.33796 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17529 GTEX-XK95-1026-SM-4GIDV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11103 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.50694 GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850306 parbendazole-3799 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.46563 NCIH1792 CCLE Cell Line Gene CNV Profiles -1.0 -1.48972 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91112 GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00228 BRD-K61486072 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04634 dydrogesterone-4254 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HCT 116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41088 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.07053 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.4474 BRD-K35596700 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28145 benfluorex-6727 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K41714444 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15425 GTEX-X5EB-1726-SM-4E3J7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52749 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.905709 Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZK-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16038 CHP126 CCLE Cell Line Gene CNV Profiles 1.0 1.99253 BRD-K51568355 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51616 Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04965 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27552 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884376 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 1.59436 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.952697 GTEX-XQ8I-2126-SM-4BOOM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12185 BRD-K84278600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.02622 GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13707 GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45061 GTEX-WH7G-0926-SM-4LVMJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.33866 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.47565 Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938723 layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29903 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.98933 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nifuroxazide-4253 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3007-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K54934070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.47222 BRD-K11905754 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24199 BRD-K95615652 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25804 GTEX-XOTO-0826-SM-4B65O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998577 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.15225 BRD-K24640918 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17394 NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 1.50842 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930944 GTEX-Q2AH-0226-SM-48U1I GTEx Tissue Sample Gene Expression Profiles 1.0 0.967764 SLR23 CCLE Cell Line Gene CNV Profiles -1.0 -1.50557 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63665 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.931006 Prostate adenocarcinoma_PRAD_TCGA-HC-7820-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.253 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K45520793 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27727 GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.22127 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12788 GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.04058 Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H847 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 locus ceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11519 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KL-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0826-SM-4AT4D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3093 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17218 BRD-K01152687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17045 BRD-K52977489 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3937 Brain Lower Grade Glioma_LGG_TCGA-HT-7877-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K19567079 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21761 dapsone-5078 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QDVN-1026-SM-48TZA GTEx Tissue Sample Gene Expression Profiles 1.0 0.930191 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.31381 Lung squamous cell carcinoma_LUSC_TCGA-56-A4BY-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7875-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K70148257 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07688 LXF289 CCLE Cell Line Gene CNV Profiles -1.0 -1.66381 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.904579 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K76701247 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.33068 KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02708 GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07462 BRD-K95428783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.80956 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.836172 IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.975454 supraoptic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.57 substantia nigra, pars compacta, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06155 Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIG-M5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.9166 GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20431 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.57624 BRD-K48756106 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47538 GTEX-T6MN-0226-SM-32PMD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29252 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16152 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.849837 BRD-K62497619 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38838 BRD-K52194153 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16592 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSG-1726-SM-4KKZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.12946 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.944558 BRD-K27011412 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48988 BRD-K15160749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01914 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61939 BRD-K63568016 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18465 DLD1 BioGPS Cell Line Gene Expression Profiles 1.0 2.41625 GTEX-PLZ6-0126-SM-48TC6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40723 GTEX-WH7G-1626-SM-4LVMY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13009 GTEX-SNMC-0926-SM-4DM5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44134 dacarbazine-4480 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 1.11315 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0393 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12504 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A57457448 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.01574 GTEX-XUZC-0426-SM-4BOPE GTEx Tissue Sample Gene Expression Profiles 1.0 0.992646 BRD-K67734449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00035 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.35075 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09457 GTEX-V955-1126-SM-4JBH3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.837959 BRD-K48407262 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14018 BRD-K01417352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.10023 ergocalciferol-6746 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K10133810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.51707 PRC1_BMI_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations 1.0 null GTEX-U3ZN-1726-SM-4DXUQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.899895 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18736 LN382 CCLE Cell Line Gene CNV Profiles -1.0 -1.3733 BRD-K86263698 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19569 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null stratum oriens of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34499 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04136 thioridazine-4454 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K30977850 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15108 estropipate-4472 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93622 GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825566 BRD-K66865641 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5164 GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891641 CEACAM8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00472434 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.85052 Brain Lower Grade Glioma_LGG_TCGA-DU-6397-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hyoscyamine-5099 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null tamoxifen_homo sapiens_gpl570_gds4095 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.920274 GTEX-UTHO-2726-SM-4JBH9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830556 SNU449 CCLE Cell Line Gene CNV Profiles 1.0 1.58552 GTEX-T6MN-0326-SM-32PMK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07402 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03782 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.908286 BRD-K88274759 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.56711 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53427 GTEX-XK95-0426-SM-4AT4R GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 BRD-K31644794 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.11891 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.955492 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 2.02326 neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.072794 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.62936 GTEX-S7SE-0008-SM-33HB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48632 BRD-K56729241 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.2612 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13916 IC-86621-7548 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.947232 GTEX-V1D1-1926-SM-4JBGX GTEx Tissue Sample Gene Expression Profiles 1.0 1.19849 BRD-A89499670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40635 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.897514 BRD-K78003637 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18232 BGC823 CCLE Cell Line Gene CNV Profiles 1.0 1.38766 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8314-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K22443456 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.07224 BRD-K31666794 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00639 GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.02234 GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15921 GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25618 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5901-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH2452 CCLE Cell Line Gene CNV Profiles 1.0 2.14995 GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00255 BRD-K97839095 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58567 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932117 Brain Lower Grade Glioma_LGG_TCGA-P5-A77W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU-DHL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19033 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17604 BRD-K66754362 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12768 CP-320650-01-4557 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-OOBK-0726-SM-3LK5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3655 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00461 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836063 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FS-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.84979 BRD-K47886441 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30348 orciprenaline-4248 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28401 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11739 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YD15 CCLE Cell Line Gene CNV Profiles 1.0 1.33513 GTEX-XQ8I-1426-SM-4BOPW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12685 BRD-K31273080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81142 BRD-K74600148 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13288 BRD-K06332513 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32051 BRD-K22748970 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.20532 BRD-A42612443 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03008 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046445 GTEX-U3ZH-0426-SM-4DXSE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.950121 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78196882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85684 BRD-K37055068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17923 furaltadone-4313 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58194 NCIH2085 CCLE Cell Line Gene CNV Profiles -1.0 -2.24381 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.48745 GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834917 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWCY-0726-SM-48TCS GTEx Tissue Sample Gene Expression Profiles 1.0 1.31677 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.68833 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.984216 GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15083 SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19033 GTEX-SNMC-0426-SM-4DM5Y GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22521 BRD-K00046588 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02957 SNB75 CCLE Cell Line Gene CNV Profiles -1.0 -2.59342 BRD-K76942055 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14382 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.16038 GTEX-SNOS-0526-SM-4DM54 GTEx Tissue Sample Gene Expression Profiles 1.0 0.947453 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01838 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K42214389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14551 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47972 Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00317 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42833 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041142 haloperidol-4427 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K17259076 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26097 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.20637 BRD-K46082763 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44528 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911951 OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30795 SW1271 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 1.20797 GTEX-S7SE-0926-SM-2XCD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.954026 BRD-K13788250 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08748 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07929 BRD-K24156533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77825 Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41088 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57187 Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K67096634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4558 BRD-K03953354 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13424 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYVS-0326-SM-3NM9V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09163 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 2.41021 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.60577 tilorone LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.76018 COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862507 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.955509 Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78681155 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.7392 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21939 BRD-K24377650 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.60034 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07929 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.859169 Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K93933512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01191 GTEX-P4PP-0626-SM-3NM9X GTEx Tissue Sample Gene Expression Profiles 1.0 1.19121 BRD-K68575551 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.94507 BRD-K14778436 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71416 BRD-K21897482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.66324 BRD-K47984776 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.48364 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56407 BRD-K42455150 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15454 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 BRD-K19327124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59316 GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851104 BRD-K76706127 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2624 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31741 brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.067301 Brain Lower Grade Glioma_LGG_TCGA-DU-7009-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MQ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22375 BRD-K23589316 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14786 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08753 BRD-K43820045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20478 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.25821 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.838262 BRD-K03935681 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05542 CCRT CEM BioGPS Cell Line Gene Expression Profiles 1.0 1.43209 BRD-K00137579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29694 BRD-K17659275 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96825 GTEX-R53T-1126-SM-48FD4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00298 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.06899 SCARA5 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00550262 BRD-K59975583 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36294 BRD-K08817808 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64545 Sarcoma_SARC_TCGA-DX-A48L-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K96604397 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62735 MOLP-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.931906 BRD-K81574470 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12255 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.968629 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98181 CHP212 CCLE Cell Line Gene CNV Profiles 1.0 2.15699 Prostate adenocarcinoma_PRAD_TCGA-EJ-8468-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K05286676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52393 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04916 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38082 GTEX-PLZ6-0726-SM-3P619 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46884 inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.825966 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.54579 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41106 Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BICR22 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 PL45 CCLE Cell Line Gene CNV Profiles 1.0 1.52177 BRD-K26306512 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.06403 VZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43799 novobiocin-4569 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 3.12962 Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87779720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07908 HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -1.08156 stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06991 GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40032 BRD-K64531971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.17783 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882666 dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.204593 Rectum adenocarcinoma_READ_TCGA-DC-6160-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K26402831 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13342 Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chrysophanic-acid LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30861 BRD-K28448768 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.87026 GTEX-S7SE-0126-SM-2XCD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20586 BRD-K98465548 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33105 BRD-K01667746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30875 NCIH1184 CCLE Cell Line Gene CNV Profiles 1.0 1.54507 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11699 BRD-K47848960 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03931 Lung squamous cell carcinoma_LUSC_TCGA-J1-A4AH-01A-31R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-1426-SM-4IHLQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.13217 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XK-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 2.84013 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K71538933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.45116 propranolol-6759 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PANC1005 CCLE Cell Line Gene CNV Profiles 1.0 1.37083 GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53201 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 0.875282 MZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01754 quercetin-4264 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19033 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09877 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K35681049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.61081 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01678 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11213 BRD-K35132745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19736 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.910974 vincamine-3784 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4998-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11548 BRD-K50008138 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05477 GTEX-T6MN-0926-SM-32PLX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.88514 BRD-K99119142 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43853 specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.344207 GTEX-U8XE-0426-SM-3DB91 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836453 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.98757 locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15233 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K44481920 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34297 BRD-K21535473 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25753 BRD-K57626519 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46931 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.823967 GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850547 GTEX-OIZI-1426-SM-3NB1T GTEx Tissue Sample Gene Expression Profiles 1.0 1.2932 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K70408591 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19717 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.12201 GTEX-O5YV-1026-SM-3LK72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25174 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1016 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13776 BRD-K63787803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27489 JURKAT BioGPS Cell Line Gene Expression Profiles 1.0 1.67882 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12235 GTEX-P4QT-0626-SM-3NMCP GTEx Tissue Sample Gene Expression Profiles 1.0 1.30932 muscle GTEx Tissue Gene Expression Profiles -1.0 -1.58926 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.959716 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17505 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.97479 Lung adenocarcinoma_LUAD_TCGA-44-2666-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -0.870381 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K26976202 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02451 JP-4-043 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36403 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60477 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.77325 BRD-A57285050 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28388 GTEX-N7MT-1926-SM-3LK5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.02083 lithocholic acid-4551 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K67270926 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14568 procyclidine-4233 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934974 BRD-K40251180 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.1669 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00623 Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BECKER CCLE Cell Line Gene CNV Profiles -1.0 -1.66248 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.956308 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.50154 clomipramine-4487 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZR-75-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31378 CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41302 GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68578 SARS-CoV_84Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.6258 HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.64686 pyramidal cells of rostral CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10209 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77818 Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69074358 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04426 HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.845994 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.38171 MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862507 GTEX-PX3G-2626-SM-2I3EG GTEx Tissue Sample Gene Expression Profiles 1.0 0.840726 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0213 OVKATE CCLE Cell Line Gene CNV Profiles 1.0 2.44862 BRD-K34721572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29912 BRD-K03765511 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59356 SARS-CoV_96Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.7948 GTEX-R53T-0526-SM-3GADL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02989 BRD-K83135157 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.66153 BRD-K30171122 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37946 BRD-K67194214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.47254 GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles 1.0 0.925822 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.45459 GTEX-UPK5-0003-SM-3NMDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.915493 EM2 CCLE Cell Line Gene CNV Profiles 1.0 1.62044 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881198 BRD-K13049124 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69914 BRD-K73145196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.96073 TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 BRD-K34701680 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.08792 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K87920761 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07831 PDE6G LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00501263 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24925 BRD-K10089296 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59056 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48837 BRD-A73618687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.09396 Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46508 BRD-K29713418 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.56504 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70067 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910885 carcinine-4225 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.8426 GTEX-X4XY-0526-SM-46MW1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.911013 GTEX-T6MN-1526-SM-4DM5P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22302 GTEX-PWOO-0826-SM-48TCL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20079 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.137651 GTEX-XQ8I-1126-SM-4BOO2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.623 BRD-K70262646 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3233 GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54343 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85902 Brain Lower Grade Glioma_LGG_TCGA-TM-A84G-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12749 pindolol-4496 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-U3ZH-0526-SM-3DB75 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.239 BRD-K99824630 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00682 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02317 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873985 GTEX-SE5C-1226-SM-4BRWV GTEx Tissue Sample Gene Expression Profiles 1.0 1.07917 SHSYSY-RA BioGPS Cell Line Gene Expression Profiles -1.0 -1.07316 GTEX-NPJ8-0326-SM-2D7VV GTEx Tissue Sample Gene Expression Profiles 1.0 0.987645 GTEX-WY7C-2126-SM-3NB2R GTEx Tissue Sample Gene Expression Profiles 1.0 0.909097 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20188 BRD-K81725246 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22062 BRD-K25540102 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08072 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.999743 BRD-K89668690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05661 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963035 monorden-4443 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00276 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07706 BRD-K50603336 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.26163 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07691 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.71043 BRD-K53619784 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.74943 BRD-K85395981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.20196 Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K90882192 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36347 BRD-K22383829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58544 LB2518-MEL COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 BRD-K14087001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03681 BRD-K18094884 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.09499 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K73176613 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17268 GTEX-QEL4-0726-SM-3GIJ5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.868771 allantoin-5052 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K43284834 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81472 BRD-K38791044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84287 GTEX-S4UY-1626-SM-4AD55 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09169 developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30342 BRD-K77316284 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18669 BRD-K24496049 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18511 BRD-K68853384 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26248 HL60 CCLE Cell Line Gene CNV Profiles -1.0 -1.42188 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46171 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944391 GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28777 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0528 BRD-K56802897 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.83834 BRD-K30853940 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29183 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41106 MM.1S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.86721 Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K79965790 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28258 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964534 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.17519 stratum pyramidale of caudal CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911215 ceftazidime-5054 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null clonidine-4478 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K80066561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44236 Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null desoxycortone-6758 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 2.01051 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73846 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912684 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896431 BRD-K17675924 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.65383 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.36695 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.856565 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K06152379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32842 OE19 CCLE Cell Line Gene CNV Profiles 1.0 1.44553 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040642 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.55346 BRD-K04462989 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.48678 GTEX-WH7G-1726-SM-4LVKY GTEx Tissue Sample Gene Expression Profiles 1.0 0.835199 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44583 GTEX-VJYA-0726-SM-4KL1T GTEx Tissue Sample Gene Expression Profiles 1.0 0.941587 GTEX-PLZ6-0626-SM-3P61B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75057 LIVF001-002 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19748 BRD-K86792405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23862 SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.958578 GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2659 Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3481 BRD-K56616847 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35779 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-7848-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32084247 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.41609 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.892767 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 cromoglicic acid-5754 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K69678391 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.92761 GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4903 BRD-K29711480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13818 GTEX-OHPK-1526-SM-3MJGM GTEx Tissue Sample Gene Expression Profiles 1.0 0.952991 BRD-K64039518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15057 BRD-K23782109 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03341 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55665639 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35764 Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMGI CCLE Cell Line Gene CNV Profiles 1.0 1.52999 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.915547 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.974665 Lung adenocarcinoma_LUAD_TCGA-55-8087-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34189 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MJ-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K57472585 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39196 SJRH30 CCLE Cell Line Gene CNV Profiles -1.0 -1.40396 movement disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.735433 BRD-K60044070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.157 GTEX-PLZ6-0526-SM-3P61C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59366 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.92619 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.34468 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66163 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.55805 Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K34044309 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16464 KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13776 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00951 GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32551 BRD-K04939366 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.75444 BRD-K99302735 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.06706 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36598 GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84846 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17255 GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23685 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10757 methacholine chloride-5773 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K27621887 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25377 midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50317 MED1_OE_GDS4846_11_human_LNCaP prostate cancer cell GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71901 BRD-K24039194 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26351 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.87958 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09922 BRD-A53463743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.4968 SK-N-DZ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04486 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.853539 GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988387 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K79730625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.98541 BRD-K16682693 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14105 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.53793 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.946764 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A818-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K40306365 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13598 BRD-K30199352 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0962 Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K84128738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00144 GTEX-WFG7-1126-SM-4LMK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1783 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879256 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14973 NCIH716 CCLE Cell Line Gene CNV Profiles -1.0 -1.89321 basolateral nucleus (basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38377 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15471 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 1.06093 BRD-K92910000 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.01151 Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RS11846 BioGPS Cell Line Gene Expression Profiles 1.0 0.933436 Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null icSARS CoV_12Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.28755 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.53038 Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.945591 SF539 BioGPS Cell Line Gene Expression Profiles -1.0 -2.34325 BRD-K93677460 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70949 BRD-K94489736 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22561 UACC-893 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14973 BRD-K74862734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41037 BRD-K56520530 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05478 Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K19527338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.22683 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04818 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03532 Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-2626-SM-4AT6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.35388 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00317 11-deoxy-16,16-dimethylprostaglandin E2-7538 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.979184 SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.851715 BRD-K81457218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06616 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null securinine-4493 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18712 BRD-K01334037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15435 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06102 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.92691 Brain Lower Grade Glioma_LGG_TCGA-IK-8125-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69761 cSARS Bat SRBD_0Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.11665 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.70638 GTEX-T6MN-0126-SM-32PLP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66918 GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 0.9793 BRD-K93148720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77377 fluocinonide-3757 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-XQ8I-1926-SM-4BOOK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63917 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.997776 GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.25157 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11102 BRD-K77958314 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5771 BRD-K82202634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39315 rofecoxib-463 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-NFK9-2226-SM-3MJGP GTEx Tissue Sample Gene Expression Profiles 1.0 1.0908 BRD-K93662118 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01847 BRD-A26222320 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05683 basal nucleus of meynert, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12288 BRD-K30821056 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02185 BRD-K28982281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.92922 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.41528 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.950781 Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EO-0926-SM-3P5Z2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882805 BRD-K98427581 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97832 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.80057 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.852904 SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.878977 GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924804 BRD-K04269696 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0325 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889203 BRD-K27885385 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71598 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.08168 GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894777 homosalate-3797 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.77655 BRD-K77547131 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05855 ceforanide-6751 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CAL-148 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 IBMX LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.32987 BRD-K87875370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0439 sulfinpyrazone-3192 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null flunisolide-4303 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HNT-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.895395 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JI-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.15024 ZNF831 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00520869 primaquine-4263 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null clopidol LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.00881 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 GTEX-WY7C-2326-SM-3NB2U GTEx Tissue Sample Gene Expression Profiles 1.0 0.833296 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.869128 BRD-K08715918 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62325 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22249 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.881198 BRD-K08416835 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26808 GTEX-U3ZH-1126-SM-4DXUG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47628 GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.05629 GTEX-XGQ4-0126-SM-4AT4H GTEx Tissue Sample Gene Expression Profiles 1.0 0.881045 GTEX-OXRP-0926-SM-48TC1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862051 HELA BioGPS Cell Line Gene Expression Profiles 1.0 1.15401 anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08178 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.35686 GTEX-T6MN-0826-SM-32PM4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09004 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22468 GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 1.29792 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A688-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3925-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K08431704 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12473 BRD-K57498440 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.37272 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99163 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.061343 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19729 BRD-K89770910 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23427 gallamine triethiodide-5735 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K78195641 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58756 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.977717 BRD-K74881104 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45612 GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22458 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.883119 Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45541 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.907128 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.867092 BRD-K70198986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.1294 BRD-K20119884 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00269 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940214 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.897629 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40294 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.047 HCC1482 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.855018 BRD-K96023136 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05042 BRD-K50924315 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36041 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00229 MOLT4 BioGPS Cell Line Gene Expression Profiles 1.0 1.05398 GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41986 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.48063 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K77023196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15838 NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.50402 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39118 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.27705 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01192 BRD-K44779670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17824 BRD-K26399271 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.30712 GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 0.865795 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905453 NALM-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.919222 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA9_DN.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K93698227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31764 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.885701 GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0242 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78606 GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.03187 Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 0.947059 diclazuril LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.27125 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834337 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 1.133 HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.39236 BRD-K95499061 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.81926 BRD-K18657361 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42614 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 1.89566 Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ6-0226-SM-3P61I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.74734 BRD-K07812227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43027 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05703 BRD-K62983405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29972 BRD-K71296038 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.24166 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.838997 BRD-K10696228 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07156 BRD-K63375777 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01627 GTEX-QLQ7-0926-SM-447BC GTEx Tissue Sample Gene Expression Profiles 1.0 1.18115 clozapine-4453 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K01978082 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.9566 BRD-K89832379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.26031 Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.47091 OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09221 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61931 BRD-K46014293 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.28273 BRD-K96120749 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9254 Uterus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.44998 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.57209 BRD-K77273085 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2558 BRD-K22137463 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35719 BRD-K83527041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44422 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7842-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K99962919 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.49054 Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932117 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.51557 Prostate adenocarcinoma_PRAD_TCGA-EJ-5505-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K06772291 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10908 BRD-K65828139 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.7182 BRD-K72745710 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30275 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05274 GTEX-W5WG-1626-SM-4LMKG GTEx Tissue Sample Gene Expression Profiles 1.0 0.953292 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04987 etilefrine-4590 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28918 Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K65780164 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44835 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31741 BRD-K09395335 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02937 Brain Lower Grade Glioma_LGG_TCGA-HT-7480-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null (+/-)-catechin-4255 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K25138450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2723 GTEX-PWN1-0626-SM-48TDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.919449 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.858011 NCIH1666 CCLE Cell Line Gene CNV Profiles -1.0 -1.43485 BRD-K95900761 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18288 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fulvestrant-4429 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null tolazoline-4262 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.946393 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.128 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.061919 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.58163 GTEX-T6MN-0011-R2A-SM-32QOW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36785 BRD-K08199068 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00124 MTOR_UP.N4.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null BRD-K66821167 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15618 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.18471 Lung adenocarcinoma_LUAD_TCGA-55-6971-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22457 GTEX-XQ8I-2326-SM-4BOQC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75431 GTEX-XMK1-2626-SM-4B65R GTEx Tissue Sample Gene Expression Profiles 1.0 1.00947 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.19009 GTEX-OOBJ-0926-SM-48TDO GTEx Tissue Sample Gene Expression Profiles 1.0 1.36065 Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K24700188 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14333 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K32520360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58393 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05274 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34933 GTEX-PSDG-1326-SM-48TD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06812 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856773 BRD-K31606237 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.38661 proxyphylline LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06286 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.983207 BRD-K29301364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62266 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867504 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867706 BRD-K59701963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70994 GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.987956 BRD-K27911943 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84323 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -1.55619 BRD-K23956044 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.974 BRD-K63937112 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22957 dantrolene-3786 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886781 Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K74096348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.95932 BRD-K81656074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77277 BRD-K40210962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13227 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57066 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07028 GTEX-T6MN-1126-SM-4DM71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61366 GTEX-WYVS-0526-SM-3NM9W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51454 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-A62787624 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77445 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7864-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K80622162 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03069 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.50449 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81644 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09179 MFE-319 COSMIC Cell Line Gene CNV Profiles -1.0 -3.48261 BRD-K31354456 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5604 GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35092 BRD-K57293986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03556 GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles 1.0 0.85732 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00624 BRD-K35587518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15062 salivary gland GTEx Tissue Gene Expression Profiles 1.0 1.91096 BRD-K42511168 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4057 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30445 BRD-K82082713 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19348 BRD-K36544054 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71921 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4862-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K48516290 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16433 GTEX-UJMC-1226-SM-4IHLI GTEx Tissue Sample Gene Expression Profiles 1.0 0.957362 GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88244 CAPAN-1 Klijn et al., Nat. 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Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.95451 BRD-K33770771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.51963 oxolinic acid-5094 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-RTLS-1126-SM-46MUQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.19449 Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.40678 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869211 BRD-K13279882 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0984 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.932117 liver GTEx Tissue Gene Expression Profiles -1.0 -1.24114 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22375 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 3.9024 ITK_defectivemutant_125_GSE28200 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.69416 BRD-K76461283 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30419 GYPB LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00756057 mexiletine-3781 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 2.03778 GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30141 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.46832 chlorpromazine-5074 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VB-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856388 BRD-K21206585 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19403 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913522 gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.472736 Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.43086 BRD-K50677542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12827 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16038 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.30405