association	dataset	threshold value	standardized value
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81832
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31321
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12797
COLO680N	DepMap CRISPR Gene Dependency	1.0	7.09483
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53095
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8581
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.059
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4997
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5984
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4115
UBQLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1587
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44904
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20427
TIPRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92887
SESN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56921
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38063
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.5378
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77759
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03714
MM485	DepMap CRISPR Gene Dependency	1.0	2.25676
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20837
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF431	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41224
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7902
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5757
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86676
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33537
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.3712
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17662
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68426
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.973
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H103	DepMap CRISPR Gene Dependency	1.0	2.1047
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7096
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92601
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25136
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62743
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59659
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6507
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0306
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NH12	DepMap CRISPR Gene Dependency	1.0	3.21451
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149010_0_v_6_dars2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1105
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16193
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11854
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9734
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.3189
MAVER1	DepMap CRISPR Gene Dependency	1.0	3.12846
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.806
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147613_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEx SmallIntestine 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.58677
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07655
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6599
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7199
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.017
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32155
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.816
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29808
GSE121824,GSE121826_0_v_3_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4088
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2698
PANC0327	DepMap CRISPR Gene Dependency	1.0	6.07728
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SKGII	DepMap CRISPR Gene Dependency	1.0	3.19444
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60364
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CYLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61687
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247764_5_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133213_9_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07765
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09962
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21969
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33587
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8315
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.18
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7007
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04813
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15897
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89795
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27294
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2154
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06456
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.27
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.015
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77256
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.751
SASS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.5384
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6322
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32555
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	227.091
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72022
GSE182680,GSE182683_10_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160246_9_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00769
NZM42	DepMap CRISPR Gene Dependency	1.0	2.1389
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61958
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4654
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64414
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9037
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0923
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45528
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15228
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-7.82121
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8711
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07615
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2508
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95401
CAPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30982
F5	DepMap CRISPR Gene Dependency	1.0	2.43724
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11568
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4406
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19026
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21748
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45377
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4777
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8296
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UPCISCC029A	DepMap CRISPR Gene Dependency	1.0	4.08062
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.1928
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31817
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55846
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79333
PSMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84611
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84937
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35239
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	6.05807
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154074_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138872,GSE138874_0_v_1_il33_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.64034
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48099
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6021
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18068
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03301
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81201
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18803
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01315
DMS53	DepMap CRISPR Gene Dependency	1.0	4.76894
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04156
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29397
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4067464-onc2013378x3.xls-Sheet1-Supplementary_Table_1_Top_1000_E2F4_Chip-Seq_targets_that_are_repressed_by_p53_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9891
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97497
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.9077
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12376
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.377
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1191
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF4E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31043
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LYSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10712
GSE133213_9_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.5282
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7023
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8633
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_1_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4615
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.35
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09309
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39941
ZRANB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27491
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5253
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	202.071
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0805
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9864
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83181
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12716
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03894
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29131
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20462
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JHU011	DepMap CRISPR Gene Dependency	1.0	2.17385
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8711
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06468
PFKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24288
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10120406-JEM_20220962_DataS2.xlsx-Elf1_target-Data_S2_List_of_Elf1-target_genes_2_d_after_LPS_pIpC_stimulation_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74204
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6087
JHU022	DepMap CRISPR Gene Dependency	1.0	5.85369
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63931
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4408
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34871
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63692
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_3_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0274
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39212
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8374
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3847
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54118
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09376
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43289
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.9395
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5288
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5523
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0937
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43848
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1471
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72695
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05553
Aliskiren_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00576613
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169155_3_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97026
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DIRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13125
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22522
TSPAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18793
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57997
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52041
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13407
GSE93309_5_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.26
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2141
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95795
SNU1079	DepMap CRISPR Gene Dependency	1.0	3.12612
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1771
GSE137914_2_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5931
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.9048
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47625
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12057
HSC3	DepMap CRISPR Gene Dependency	1.0	8.31234
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2163
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE198380_0_v_1_phgdh_human	RummaGEO Gene Perturbation Signatures	1.0	null
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97226
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02553
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64902
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.277
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3238
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARFGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38084
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08893
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50936
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48352
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4015
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.734
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
GSE160442,GSE160444_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.8438
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
UPCISCC111	DepMap CRISPR Gene Dependency	1.0	4.54045
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5304
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46929
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.09242
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40676
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.089
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03347
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3123
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3492
GSE119564_2_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
ARHGEF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86647
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38578
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	9.98984
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46408
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8763
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99994
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_5_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9635
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Blood 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-11.9393
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87394
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39499
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.113
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9241
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9467
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
PCI30	DepMap CRISPR Gene Dependency	1.0	2.47197
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC25	DepMap CRISPR Gene Dependency	1.0	2.92496
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
THBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21487
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7381
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7375
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89137
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2546
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53093
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKGT2	DepMap CRISPR Gene Dependency	1.0	2.301
FAM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97593
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01728
GSE210885_3_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02025
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1475
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45532
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5346
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6429
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44275
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09325
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.0794
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32041
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40654
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63384
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11132
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75197
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12777
EPLC272H	DepMap CRISPR Gene Dependency	1.0	11.1697
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36817
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18607
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.3336
PMC12532594-41380_2025_3119_MOESM1_ESM.pdf-124-ST18_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
NAA60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07276
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	249.892
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01995
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12636
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83583
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04132
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34298
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58079
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70523
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.466
GOLGA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41229
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1667
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2546
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.6424
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9181
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0386
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.88
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37933
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66528
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34776
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44185
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54537
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00841
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11966
OE21	DepMap CRISPR Gene Dependency	1.0	17.2364
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.8271
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	3.23042
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF283	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91539
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.498
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11329
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6747
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27334
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09215
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.057
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48413
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51458
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08256
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null