association dataset threshold value standardized value GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null ECI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2629 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6384 PFSK1 DepMap CRISPR Gene Dependency 1.0 5.86223 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.38228 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.19933 GTEX-S4P3-0426-SM-4AD56 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.906532 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE184902_4_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null rectum_8a HPA Tissue Sample Gene Expression Profiles 1.0 0.830296 PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Small_Intestine Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 2.39412 capan2 HPA Cell Line Gene Expression Profiles 1.0 2.11396 Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null golgi apparatus LOCATE Predicted Protein Localization Annotations 1.0 null HS3ST3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05472 CTDNEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78223 OCUM1 CCLE Cell Line Gene Expression Profiles 1.0 2.36489 Interanterodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39976 LS1034 CCLE Cell Line Gene Expression Profiles 1.0 1.53535 ZNF132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.99372 hsa-miR-186 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SF268 CCLE Cell Line Gene CNV Profiles 1.0 1.67367 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.53644 striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.83902 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.903574 SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -1.78298 GSE186005_1_v_2_klf5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70278 496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.97597 GSE179974_3_v_5_carboplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null 496100500_PCx_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.21331 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PARPBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35145 ACOT13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29172 MAPK14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6292 GSE157594_0_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null RAB11FIP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32628 ITSN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53646 PLEKHA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52153 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6096 Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4699-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 COL4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30127 nucleus subceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.924437 BEND6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44736 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09447 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75C-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK11IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82033 RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07764 NELFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41357 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTGR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2264 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.858641 GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89475 PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-579 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 EDNRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1381 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24307 PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1 Rummagene Transcription Factor Associations 2026 1.0 null PSMC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10003 GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles 1.0 0.923111 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47041 Small_Intestine-transit amplifying cell of small intestine Tabula Sapiens Gene-Cell Associations 1.0 0.391494 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71139 GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 0.956878 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829177 GSE157594_6_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null KP1N DepMap CRISPR Gene Dependency 1.0 2.40486 ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.2781 GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles 1.0 1.04192 abnormal neutrophil cell number GWASdb SNP-Phenotype Associations 1.0 0.666599 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05443 central lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28363 Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.5146 PCIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68182 GSE206729_2_v_0_trps1_human RummaGEO Gene Perturbation Signatures 1.0 null BECKER CCLE Cell Line Gene CNV Profiles 1.0 1.70891 MIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70718 PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04691 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles 1.0 1.31611 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.1368 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null stomach HPA Tissue Protein Expression Profiles 1.0 1.9514 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.97985 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2614 AGL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9536 GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4715 liver HPA Tissue Protein Expression Profiles -1.0 -0.74109 GSE152032_0_v_1_s1pr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE73561,GSE73563_0_v_1_mef2c_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.947594 Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RH30 CCLE Cell Line Gene CNV Profiles -1.0 -2.00442 JRA - Juvenile rheumatoid arthritis_Peripheral blood mononuclear cell_GSE7753 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.41191 GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RREB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36275 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88866 PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1687 AMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81833 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10816 H4C6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.70545 hsa-miR-4695-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.2345 GSE112860_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R53T-1326-SM-48FCQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.979746 ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6704 FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02947 orbital frontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05637 GTEX-X638-0426-SM-47JY2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.865744 CTDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15524 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0917 rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31923 GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 1.15418 UGCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13489 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.831348 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24086 LANCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79341 Mediodorsal nucleus of the thalamus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.31149 CHD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73351 H3K9me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PGBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21758 HUO9 COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6041 ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37883 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548aj TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.088671 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11551 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles 1.0 2.70679 CHPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99921 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38313 PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18 Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-CI-6624-01C-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13733 GTEX-P4PP-1426-SM-3NM9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.2764 GTEX-XK95-0008-SM-4AT5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.05852 GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 BAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45143 RHOXF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96942 superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19322 GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 1.00702 gastrointestinal cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null MSANTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89872 eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.831767 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.846354 GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992982 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54931 SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2399 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.181 BLOC1S4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33878 periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04221 KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4892 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.08763 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03481 GSE158182_5_v_0_pnpla3_human RummaGEO Gene Perturbation Signatures 1.0 null FBH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97042 MPV17L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67019 GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 1.05495 Central lateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5845 GTEX-WFJO-0002-SM-3P61X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21636 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7987_KO_Id1_SRP147556 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.5846 IFI27L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66761 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11935 gallbladder HPA Tissue Protein Expression Profiles 1.0 1.9514 Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18003 hsa-miR-302d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Ezh2_deficiency_GDS2717_141_mouse_lymph node T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XUJ4-2026-SM-4BOOW GTEx Tissue Sample Gene Expression Profiles 1.0 1.21374 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.67952 hsa-miR-373 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE179974_3_v_4_carboplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null PPWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29381 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9048_OE_PRRX1B_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.3813 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05265 CTCF_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92327 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.97342 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IDH3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69418 abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.1821 km3 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VJYA-0926-SM-4KL1N GTEx Tissue Sample Gene Expression Profiles 1.0 2.29757 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.9017 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10168 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19754 TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null hsa-miR-511 TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 hsa-miR-664 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54702 GTEX-P44H-0526-SM-2XCF1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.887104 GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00385 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.926631 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98238 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles 1.0 1.5887 TWNK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40519 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 1.53162 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4887-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.055904 colon GTEx Tissue Gene Expression Profiles 1.0 0.936802 GTEX-S3XE-1726-SM-3K2AM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824075 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20705 NCIH1385 CCLE Cell Line Gene Expression Profiles 1.0 1.43624 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.121 TMEM201 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17681 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13619 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11983 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null NCIH2085 CCLE Cell Line Gene Expression Profiles -1.0 -1.6649 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.856771 GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles 1.0 0.883584 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28044 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.39159 GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles 1.0 0.952062 SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01479 Perturb_9409_Mut|KO_Kras_SRP272482 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.64006 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9262 CRKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07723 CTCFL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.74749 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0118 RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10204 ILRUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15494 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24323 lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78192 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19363 rt4 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 Mastitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 IKZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23212 FAM133B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71279 CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0753 GSE110440_2_v_0_rad21_mouse RummaGEO Gene Perturbation Signatures 1.0 null kidney HPA Tissue Protein Expression Profiles 1.0 1.10431 ZC3H14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32969 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70328 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 NB13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-1326-SM-4GIDU GTEx Tissue Sample Gene Expression Profiles 1.0 4.2016 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles 1.0 1.51805 STYXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93348 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01751 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S3XE-2026-SM-3K2B5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61364 UACC893 DepMap CRISPR Gene Dependency 1.0 5.01384 GSE206226_2_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.7524 nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0817 GSE48812_2_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null A172 CCLE Cell Line Gene Expression Profiles -1.0 -1.49792 wm115 HPA Cell Line Gene Expression Profiles 1.0 0.976373 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsal peduncular area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03971 GTEX-QESD-0008-SM-447B2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.965605 DDX24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.06194 KU1919 CCLE Cell Line Gene Expression Profiles -1.0 -1.49789 stomach_3a HPA Tissue Sample Gene Expression Profiles 1.0 0.931339 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36734 IKZF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44673 TRAPPC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83117 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29453 Cell surface furrow COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.339 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 124.113 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02071 GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04843 Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colorectum TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03618 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.19854 Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.15 EZH2 ENCODE Transcription Factor Targets 1.0 null CDV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26543 fastigial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913264 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4177 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9544 AJUBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11115 GSE219195_0_v_2_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null 496100460_TCx_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.01465 GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02641 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE130383_2_v_0_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CALCOCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39741 hsa-miR-548x TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63985 TACSTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32889 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.44434 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 50.3686 Lobule II, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0751 SOX10 JASPAR Predicted Transcription Factor Targets 1.0 null rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07222 Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41918 Perturb_10293_KO_Ctrp1_SRP187060 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.53123 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839999 CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.50375 SHISAL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47973 C2orf74 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60171 KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03653 intermediate stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21489 GSE234340_9_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.1821 GSE210655_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE48812_2_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5087 Prelimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07098 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66682 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6162 cuneiform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891795 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.848708 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.25672 8505C CCLE Cell Line Gene Expression Profiles -1.0 -2.53776 GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles 1.0 1.88513 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29999 ASB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48436 PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null Primary somatosensory area, lower limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18003 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8373 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14719 mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11365 H2AFZ ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMK1-1726-SM-4B64Z GTEx Tissue Sample Gene Expression Profiles 1.0 2.01104 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.829599 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07357 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null leukopenia GWASdb SNP-Phenotype Associations 1.0 0.666599 HUH-7 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 GTEX-UPIC-1726-SM-4IHKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.15998 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55024 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0988 SPINDOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78715 Ischemic bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 LRP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02262 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0615 Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40181 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE180641_0_v_1_zfp503_mouse RummaGEO Gene Perturbation Signatures 1.0 null EPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96055 NFIB-24661679-E16.5 LUNG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.44685 Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2E2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58853 A375 CCLE Cell Line Gene Expression Profiles -1.0 -1.9437 DCUN1D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78871 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0054 SHANK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56035 SOX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5679 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-OXRO-0326-SM-33HBM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11258 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0026 Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 0.895094 MGA::EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0773 GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 0.894871 Medial geniculate complex, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63518 pancreas_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 RH18 CCLE Cell Line Gene CNV Profiles -1.0 -1.32725 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7555 Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20012 JHOM2B CCLE Cell Line Gene Expression Profiles 1.0 1.84861 Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WX-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P78B-0008-SM-48TE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14828 MAZ ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UPCISCC131 DepMap CRISPR Gene Dependency 1.0 2.00873 GSE174498,GSE174500_5_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18506 COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -1.9715 GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles 1.0 1.94329 LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ESCO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61561 lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27232 MG63 CCLE Cell Line Gene CNV Profiles 1.0 2.36423 GSE129772_2_v_3_runx3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE151090_0_v_4_verteporfin_human RummaGEO Drug Perturbation Signatures -1.0 null karpas707 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 mediodorsal nucleus of thalamus_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08859 SK-MEL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null USF2 JASPAR Predicted Transcription Factor Targets 1.0 null DMTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97516 disease GWASdb SNP-Disease Associations 1.0 0.027291 t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.3615 PRKCG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73376 CCDC88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52977 NYNRIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44061 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42251 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.10531 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.636 THRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83834 FOXR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34254 NCIH1930 CCLE Cell Line Gene Expression Profiles -1.0 -1.47161 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 1.59398 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles 1.0 1.07861 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE120595_0_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30266 RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.3776 Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11859 core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12392 r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10064 LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936531 mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22046 CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49361 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.11725 ARL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40269 upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.903651 PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-320b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE120370_4_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68777 ventral posterior lateral nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.857054 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11784 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3816 NSD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0086 GTEX-W5X1-2826-SM-3GILM GTEx Tissue Sample Gene Expression Profiles 1.0 0.942228 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.34394 Perturb_11972_KO_Soat1_SRP235547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE208254_4_v_2_irf8_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838592 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3716 Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158431_2_v_0_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null KALS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16121 PRKAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20151 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.7492 GTEX-SSA3-0326-SM-32QPS GTEx Tissue Sample Gene Expression Profiles 1.0 1.62934 496100287_TCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30927 ISTMEL1 DepMap CRISPR Gene Dependency 1.0 4.57609 DAPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13008 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31258 GSE79663_2_v_0_tcf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-8584-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P32-ISH COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE193258,GSE193259_9_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960471 ESR1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE234340_1_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93853 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01593 GSE216757_4_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60235 H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NR1H4::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3283 496100457_TCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05742 GSE186647,GSE217287_1_v_3_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null GSE157777_1_v_3_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NSUN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02265 PRR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86685 small intestine HPA Tissue Protein Expression Profiles 1.0 1.9514 SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.929623 Glycogen storage disease IXb DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.405 intermediate stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03149 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.14441 GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37122 p1 part of the pararubral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19494 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831458 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14084 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1842 UFL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38634 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17829 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6256 BT-483 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU5F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28676 EBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22761 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14632 GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles 1.0 1.0082 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16684 GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972088 PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WFON-0001-SM-3P61W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19325 KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.51414 TOR2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82032 GSE205976,GSE205978_1_v_4_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3272 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 CBLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3936 GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.6069 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5931 RAPGEF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16893 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null RDX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38263 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPATA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70325 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU16 CCLE Cell Line Gene Expression Profiles 1.0 1.63834 Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1306 GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08574 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00008 superficial stratum of r2BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61272 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE136622_2_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Taenia tecta, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08583 posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.43089 MFSD6L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74042 mediodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27692 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08209 r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06949 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T3M4 CCLE Cell Line Gene CNV Profiles 1.0 1.40892 H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRK-1726-SM-3NB16 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48823 GTEX-O5YV-1026-SM-3LK72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.907111 PCDHB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20503 Colonic cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DIMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88683 vagina HPA Tissue Protein Expression Profiles -1.0 -2.0052 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174383_4_v_0_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null TFAP2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50091 GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919142 GTEX-WH7G-0826-SM-4LVMR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.907932 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8533 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13063 mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.39217 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87257 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.0487 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26588 GSE193258,GSE193259_2_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null ANKRD33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67023 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930716 GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873815 TFAP2A JASPAR Predicted Transcription Factor Targets 1.0 null ABRAXAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40126 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.912536 Hypoglossal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02354 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles 1.0 3.14418 NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 2.99704 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48147 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35083 sublayer 6a of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27129 SW1116 CCLE Cell Line Gene Expression Profiles 1.0 1.35777 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7826 superficial stratum of AHy Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28303 CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.998499 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE214335_1_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null MAMLD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32427 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06986 Dinoflagellate cingulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.356 KDM1A_KD_GDS5055_457_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4892-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COX4I1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99012 Rectum adenocarcinoma_READ_TCGA-G5-6235-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thick Ascending Limb cell_Kidney_Mouse CellMarker Gene-Cell Type Associations 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2368 MAML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20531 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158182_5_v_7_pnpla3_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OOBJ-1626-SM-2I3F7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36051 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE132948,GSE132949_2_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null parasubthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26974 m1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43679 primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.77529 GSE157594_5_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null SCN4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21655 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.367 DBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52509 GSE157594_5_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null HUG1N CCLE Cell Line Gene Expression Profiles 1.0 1.97135 SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NECTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17569 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.147913 Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24761 GSE157594_3_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null EIF4G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13021 EDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34502 septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.03891 NCI-H661 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.313 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43878 EXOSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90244 WDR33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06271 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4884-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07204 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5046 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8555 Hajdu-Cheney syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.919 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.152 GTEX-X4EO-0526-SM-3P5Z3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.853639 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9285 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3323 NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 2.01064 amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08109 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Mesothelioma_MESO_TCGA-MQ-A6BQ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE230263,GSE230265_5_v_1_runx1_human RummaGEO Gene Perturbation Signatures 1.0 null IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.0093 dorsal lateral geniculate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.22825 CTCF_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZFYVE16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34811 EML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28329 GTEX-XUZC-1326-SM-4BRV2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44204 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966854 COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8466 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.83375 Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 Taenia tecta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11589 GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05111 GTEX-S3XE-0008-SM-3NM8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.06616 SETDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28233 primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00182 CDK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55147 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.941358 CTCF_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AI-0926-SM-48U1F GTEx Tissue Sample Gene Expression Profiles 1.0 1.61882 CL34 CCLE Cell Line Gene Expression Profiles 1.0 1.37355 OE19 CCLE Cell Line Gene Expression Profiles 1.0 1.35989 GTEX-VUSG-0008-SM-4KL24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11168 GSE139455_0_v_6_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null Longissimus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.876 oral mucosa HPA Tissue Protein Expression Profiles -1.0 -0.74109 Perturb_11973_KO_Soat1_SRP235547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.992842 SW1573 CCLE Cell Line Gene CNV Profiles -1.0 -1.41497 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887738 DGKQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57589 GSE211262,GSE211263_2_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null RIMS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36719 SNX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54674 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.33521 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2887 GSE139455_4_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null NCIH2085 CCLE Cell Line Gene CNV Profiles 1.0 2.06844 abnormality of granulocytes GWASdb SNP-Phenotype Associations 1.0 0.303584 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 120.225 ACTR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15694 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF354B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30668 LXF289 CCLE Cell Line Gene CNV Profiles 1.0 1.41388 GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839323 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.953 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0878 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Tietz syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.411 TAL1_01_152 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.44604 GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles 1.0 0.853908 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Esophagus - Mucosa GTEx Tissue Gene Expression Profiles 2023 1.0 1.38193 POLR2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28638 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null Colon - Sigmoid GTEx Tissue Gene Expression Profiles 2023 1.0 3.13453 layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09964 STAT3-18555785-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PDXP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75825 Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48545 MSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04562 GTEX-XQ3S-0008-SM-4GIDZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.975149 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.8815 GSE171572_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4427 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 GTEX-OHPM-0126-SM-2YUN9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871423 ENDOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50296 TNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48687 Hair follicle bulge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.672 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.966311 Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05867 Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.5576 NFIB-24661679-LUNG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21142 GTEX-S7SF-1926-SM-4AT5B GTEx Tissue Sample Gene Expression Profiles 1.0 1.50126 GTEX-OHPM-1426-SM-3TW8Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.36549 RHBDL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28375 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE196699_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08663 GSE122711_2_v_3_mpc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Central medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.19887 GTEX-UJMC-1326-SM-4IHLS GTEx Tissue Sample Gene Expression Profiles 1.0 1.01949 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.34215 GR-ST COSMIC Cell Line Gene Mutation Profiles 1.0 null SEPTIN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29287 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.18357 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.69564 HEP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9262 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPIP5K2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04293 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Mesenchymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 HCC827 CCLE Cell Line Gene Expression Profiles -1.0 -1.57903 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 34.9945 496100450_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.14363 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.038133 HSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35102 MGME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18126 smallintestine_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.35141 abnormality of immune serum protein physiology GWASdb SNP-Phenotype Associations 1.0 0.663645 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39264 SLC2A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45229 TOP3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22237 Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YIPF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74505 MAFK_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922058 Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17514 inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.62348 H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU5 CCLE Cell Line Gene Expression Profiles 1.0 1.78511 GTEX-X8HC-0626-SM-4E3HQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1281 liver_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 THEMIS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09973 GSE218060_7_v_4_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null BAG6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45307 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31792 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51544 Brain - Cortex GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.688402 GSE146156_2_v_3_tagap_mouse RummaGEO Gene Perturbation Signatures -1.0 null DPEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4318 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles 1.0 0.94195 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54702 GSE158197_2_v_10_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles 1.0 1.27169 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871681 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.90046 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE120595_5_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02136 SCARF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22617 Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25651 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.879698 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17458 ZNF134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.514 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles 1.0 1.28476 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.091796 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CENPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50418 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.854775 HEC1B CCLE Cell Line Gene CNV Profiles -1.0 -1.39825 YAPC COSMIC Cell Line Gene Mutation Profiles 1.0 null TFB2M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82784 CW2 CCLE Cell Line Gene Expression Profiles 1.0 1.70619 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles 1.0 1.36566 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 107.609 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11398 Peeling skin syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.162 OVCAR-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null GLIPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.69777 FKBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08249 POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-1026-SM-48TD4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.936845 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05936 NID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68225 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62431 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25269 Artery - Aorta GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.688402 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.17256 LRRC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9286 hsa-miR-320d TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PGK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77099 BICR22 CCLE Cell Line Gene CNV Profiles 1.0 1.46596 GTEX-V1D1-0003-SM-3NMDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06578 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26974 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 62.6426 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13189 organelle LOCATE Predicted Protein Localization Annotations 1.0 null inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01592 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18852 LS411N DepMap CRISPR Gene Dependency 1.0 6.02253 Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ORAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14238 SLC5A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68375 GSE140646_0_v_1_atf3_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null PDZD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76738 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998682 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4925 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.588 hsa-miR-302e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 INA6 DepMap CRISPR Gene Dependency 1.0 2.70774 hsa-miR-3673 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 EFNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24456 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null TM7SF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75011 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31323 dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.865646 MFH-INO COSMIC Cell Line Gene Mutation Profiles 1.0 null HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.45924 PDCD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71534 PSME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49898 CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null large intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null TFIP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85386 GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.86142 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45079 GTEX-XQ8I-2126-SM-4BOOM GTEx Tissue Sample Gene Expression Profiles 1.0 0.986388 GSE201361_0_v_1_mpst_mouse RummaGEO Gene Perturbation Signatures 1.0 null KYSE-70 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909987 VZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847368 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.893503 CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57491 PMC10165318-MCO2-4-e258-s001.docx-0-Down_PRP3-KD_vs_PRP3-wt_2_AR Rummagene Transcription Factor Associations 2026 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^3_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.60207 sclc21h HPA Cell Line Gene Expression Profiles 1.0 0.932502 DGKK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92534 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5949 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95157 Osteonecrosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 HBS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67484 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12282 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE225735_1_v_4_aldosterone_human RummaGEO Drug Perturbation Signatures -1.0 null MAP6D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72398 SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1756 GSE169691_1_v_2_saha_mouse RummaGEO Drug Perturbation Signatures 1.0 null VBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04943 ARL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33745 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TYSND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49819 GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07313 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV5::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2415 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles 1.0 1.1857 GTEX-UPIC-0002-SM-3NMDC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19211 HN CCLE Cell Line Gene CNV Profiles -1.0 -2.35157 SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KANSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46733 GTEX-QCQG-1626-SM-48U26 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2072 CCNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.93669 TUBB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46571 S1PR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60934 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.31006 CHD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68981 TMEM243 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69898 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00759 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922216 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE233548_3_v_0_plscr1_human RummaGEO Gene Perturbation Signatures 1.0 null small intestine HPA Tissue Gene Expression Profiles 1.0 1.29641 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03653 MERO48A DepMap CRISPR Gene Dependency 1.0 3.16679 FGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16998 GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles 1.0 1.44372 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100354_PCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10506 GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09563 PBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7984 PRPF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28571 PAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06881 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.051189 PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13751 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null smallintestine_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.56622 ZSCAN18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04202 LRRC26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03151 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 periventricular stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5655 Prostate adenocarcinoma_PRAD_TCGA-HC-A4ZV-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.841904 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100400_PCx_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19458 cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05963 MAML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24432 SLC30A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29253 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.915677 NECTIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06264 SNU407 CCLE Cell Line Gene Expression Profiles 1.0 1.54887 Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04191 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.48986 EMX2_Deficiency_GDS3173_607_mouse_Embryonic urogenital epithelium - day 10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-P4PP-0526-SM-2HMKE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846851 placenta HPA Tissue Protein Expression Profiles -1.0 -0.74109 GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31303 leukocyte disease GWASdb SNP-Disease Associations 1.0 0.333918 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1809 WDR48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64373 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, barrel field, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01479 WDR13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77845 intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18918 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06405 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28154 D502MG DepMap CRISPR Gene Dependency 1.0 2.37327 layer 5 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30117 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22247 TET2_KO_GDS4287_429_mouse_LSK - bone marrow progenitor population GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ACSM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13837 GTEX-XQ3S-0001-SM-4B64K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12003 IM95 CCLE Cell Line Gene Expression Profiles 1.0 1.48755 GSE217378_2_v_0_lin28b_mouse RummaGEO Gene Perturbation Signatures -1.0 null PNRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19149 KP3 CCLE Cell Line Gene CNV Profiles 1.0 1.39115 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.20477 SSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11459 KRT18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04335 RBM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.21769 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.61502 GSE138097_0_v_2_otx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HADHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67398 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.929744 zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.961943 A673 CCLE Cell Line Gene CNV Profiles -1.0 -2.02515 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF497 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92643 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC38A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34169 COPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96627 GTEX-OIZI-1326-SM-3NB1B GTEx Tissue Sample Gene Expression Profiles 1.0 0.977951 GSE226316_0_v_2_tead2_mouse RummaGEO Gene Perturbation Signatures 1.0 null AP3D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65996 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.82996 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04979 GSE139966_1_v_0_figla_mouse RummaGEO Gene Perturbation Signatures 1.0 null FBXL14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38043 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01343 PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null ZNF839 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41876 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.992195 HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null Glycogen storage disease IX DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.206 rostral group of intralaminar nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29564 GSE115363_1_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE174498,GSE174500_3_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29132 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.50388 DETROIT562 CCLE Cell Line Gene CNV Profiles 1.0 1.50979 GSE133691_2_v_0_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null NFYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.127 hsa-miR-4753-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 MTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37415 hsa-miR-520a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles 1.0 1.00802 SCYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07263 PIERCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16973 Medial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04698 GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17581 Lung Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.08972 layer 2 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.19663 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE234340_10_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CYP2S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54687 TM31 CCLE Cell Line Gene CNV Profiles 1.0 1.54486 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles 1.0 1.18722 GSE60837_0_v_4_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null r6 part of ventral gigangocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06293 superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17514 ELK1::HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3272 CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.812 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.034624 hsa-miR-302b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5778 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Ezh2_KO_GDS3765_515_mouse_Primary preadipocyte cultures GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Nr1h2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.2952 CLCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17448 Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72326 putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.892311 basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80661 GTEX-Q734-1126-SM-48TZY GTEx Tissue Sample Gene Expression Profiles 1.0 1.80794 all GWASdb SNP-Phenotype Associations 1.0 0.034536 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03915 GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06596 GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.37549 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8981 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles 1.0 0.896942 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 0.111328 TBL1X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39457 NCIH1793 CCLE Cell Line Gene Expression Profiles -1.0 -2.04764 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null NR2E1_01_306 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.35534 SKIC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.79275 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.831678 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11875 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835769 GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13248 BGN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8952 GTEX-X638-0008-SM-47JZ7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.972708 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24413 substantia nigra, pars reticulata, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.829812 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16762 ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.4097 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6992 striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.96351 Orbital area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43673 lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.74172 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.525 inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.39454 GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10735 Small_Intestine-intestinal crypt stem cell of small intestine Tabula Sapiens Gene-Cell Associations 1.0 0.657917 navicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2472 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870348 H3K36me3_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02214 496100423_PCx_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12553 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137702_2_v_1_selinexor_human RummaGEO Drug Perturbation Signatures -1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.08449 GSE197850_4_v_2_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_1698_KO_Kmt2c_SRP283007 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.38259 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02354 GTEX-QDVN-0008-SM-48U2D GTEx Tissue Sample Gene Expression Profiles 1.0 1.12054 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.90435 ACTN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59989 GSE233548_2_v_0_plscr1_human RummaGEO Gene Perturbation Signatures 1.0 null agranulocytosis GWASdb SNP-Disease Associations 1.0 0.769347 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01995 Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22778 GTEX-VJYA-2026-SM-4KL1K GTEx Tissue Sample Gene Expression Profiles 1.0 0.934326 GSE173873_10_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-P4QT-1426-SM-3NMCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.76573 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68777 CAOV-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-QDVJ-0005-SM-2TC5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868908 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00794 NPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88296 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52553 Large_Intestine-mature enterocyte Tabula Sapiens Gene-Cell Associations 1.0 1.25737 GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 2.28482 GSE60691_2_v_1_glutamine_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-Q2AH-1226-SM-48TZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.34452 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.98461 TSPYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.36989 Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74674 PPP4R3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69155 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04542 mRNA cleavage and polyadenylation specificity factor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.598 GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles 1.0 2.02615 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16973 ZFX-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NPPC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38832 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 NOTCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07002 GPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45851 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1015 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05064 av3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.191 NHP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08869 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14554 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03773 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32149 blood GTEx Tissue Gene Expression Profiles -1.0 -2.10021 EFCAB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00577 GSE154464_1_v_3_cdk6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE217115_2_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49491 TBC1D3K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45735 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6824-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mania GWASdb SNP-Phenotype Associations 1.0 0.439043 GSE157777_2_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.1853 METAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06775 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0668 COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09447 NPR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29703 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917378 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null orbital frontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.23889 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4163 lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16723 PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3381 Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior cingulate area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18003 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14462 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.59249 GSE200446_1_v_2_srsf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOXG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53395 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.29732 k562 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 periventricular stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47632 NCI-H2291 COSMIC Cell Line Gene Mutation Profiles 1.0 null IFNLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36299 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null TOMM40L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64408 SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE ChEA Transcription Factor Targets 2022 1.0 null motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.880897 GTEX-XXEK-0004-SM-4BRWO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13106 GTEX-S341-1926-SM-3K2BA GTEx Tissue Sample Gene Expression Profiles 1.0 0.92589 Perturb_6519_KD_S100A4_SRP105051 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.45072 medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.893656 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00842 smallintestine_4c HPA Tissue Sample Gene Expression Profiles 1.0 1.28539 NCI-H526 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K36me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55132 PMEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78691 GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.918637 GTEX-S95S-0008-SM-4AT5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.03003 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE151090_2_v_4_verteporfin_human RummaGEO Drug Perturbation Signatures -1.0 null abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.101314 GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1318 Nr1h4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3345 r4 part of reticulotegmental nucleus, shell portion Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51008 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.66677 RPL36A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96495 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10425 GSE149769_1_v_0_nlrp12_mouse RummaGEO Gene Perturbation Signatures -1.0 null FXYD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.412 CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45026 GTEX-PSDG-0226-SM-33HC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14193 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39264 Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11864178-sciadv.adq1724_sm.pdf-13-FOXL2_FOXL2 Rummagene Transcription Factor Associations 2026 1.0 null Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68777 KPNA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34635 layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04188 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null AGPAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39445 GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GP2D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16561 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0036 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 66.2491 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23325 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53326 layer 6 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29054 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55399 locus ceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43168 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67593 Melanoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.654 Stat2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 160.447 H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEP250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80918 NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 1.39132 TBP ENCODE Transcription Factor Targets 1.0 null CYB5RL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39249 placenta_6a HPA Tissue Sample Gene Expression Profiles -1.0 -0.856868 GSU CCLE Cell Line Gene Expression Profiles 1.0 3.40648 Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neutropenia GWASdb SNP-Phenotype Associations 1.0 0.666599 GSE154577_6_v_10_plagl1_human RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3614 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17829 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51912 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33113 SBK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67399 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54702 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12341 DLGAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57027 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HV-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE138019_3_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.61997 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14475 bone marrow HPA Tissue Protein Expression Profiles -1.0 -2.0052 CGTHW1 CCLE Cell Line Gene CNV Profiles 1.0 1.80764 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.846872 GTEX-WH7G-1626-SM-4LVMY GTEx Tissue Sample Gene Expression Profiles 1.0 1.18337 Sarcoma_SARC_TCGA-X9-A971-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21601 HSPA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66666 ZFAND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59784 N4BP2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89074 OVMIU COSMIC Cell Line Gene Mutation Profiles 1.0 null UM-UC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24782 GTEX-WYBS-0626-SM-3NMAS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18786 CLASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49378 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.900904 GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.960754 Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28363 GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878597 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.146 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DG-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0 Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14632 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03524 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871681 ANAPC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91092 GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles 1.0 1.15369 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Mobilized_CD34_Primary_Cells_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.04435 SEC63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13978 GSE133505_5_v_4_myf6_mouse RummaGEO Gene Perturbation Signatures 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.040844 GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1111 GSE210476_9_v_4_rutaecarpine_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S7SF-1626-SM-3K2AY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875744 NRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66717 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.7438 Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.0125 PMC12420540-44154_2025_254_MOESM1_ESM.xlsx-supplementary_S7-FST_PI_XPCLR_TGB_VS_ZSG_gene_PATZ1 Rummagene Transcription Factor Associations 2026 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_5_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ENO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5281 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.90632 IKBKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24152 TJAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14099 MRPL38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43855 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SEC23IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47641 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14632 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE133329_0_v_3_trim28_human RummaGEO Gene Perturbation Signatures 1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.74109 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905911 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypothalamic amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27692 pararubral nucleus, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09644 medial amygdala, posteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23748 GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.53481 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916788 u2197 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 ZNF593 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84645 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2751 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1253 ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24735 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83632 C11orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30307 VAMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54571 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02369 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12589 Perturb_10302_KO_Col4a3_SRP048893 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.4768 GTEX-WFG8-1626-SM-4LVMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.38714 BECKER COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24168 SCC4 CCLE Cell Line Gene Expression Profiles -1.0 -1.86516 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null molecular layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10858 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2058 DBT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73106 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49845 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.919612 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE210655_3_v_4_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IDE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82469 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 AHCTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72601 LARP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12734 GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.979385 GTEX-S4UY-0826-SM-4AD4Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.46407 GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07693 testis HPA Tissue Protein Expression Profiles -1.0 -0.74109 Universal_Human_Reference Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -2.61168 ARPC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63802 Perturb_15825_OE_Nrf2_SRP291724 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.42012 GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49655 PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3 Rummagene Transcription Factor Associations 2026 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19439 Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07641 GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.966902 SKUT1 DepMap CRISPR Gene Dependency 1.0 2.40477 ZNF256 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48163 GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12277 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07935 Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81084 Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TMEM51 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02219 GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles 1.0 0.944936 GSE227415_1_v_0_ucp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08992 RTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81862 PCCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34089 TRAPPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99229 GTEX-UJHI-0008-SM-4IHL1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.949337 duodenum_4b HPA Tissue Sample Gene Expression Profiles 1.0 1.47388 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1831 GSE226115,GSE226116_2_v_0_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07977 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0581 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9185 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SUSA DepMap CRISPR Gene Dependency 1.0 2.04014 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30117 WDR46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.48301 CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4105 glis2_17618285_kidney_lof_mouse_gpl2897_gds2817 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.419562 ATXN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15631 GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22718 GTEX-VUSG-1226-SM-4KKZF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847522 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8596-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fetal_Intestine_Large Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.23236 Perturb_2155_OE_TINCR_SRP182819 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.44972 GSE196962_2_v_6_parg_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35582 NCOR-22465074-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null METTL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.162 GTEX-S4Q7-0826-SM-4AD5E GTEx Tissue Sample Gene Expression Profiles 1.0 0.835609 GSE250518_0_v_2_trpm3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16591 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61982 Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02707 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9262 Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112860_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE112860_0_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null pontine nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28092 t47d HPA Cell Line Gene Expression Profiles -1.0 -0.826749 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.75604 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 LAPTM4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11447 GTEX-S95S-0002-SM-3NM8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03224 mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27188 GTEX-O5YT-1426-SM-3MJHC GTEx Tissue Sample Gene Expression Profiles 1.0 1.31522 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00712 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.12383 GTEX-OOBJ-1526-SM-3NB1Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.63774 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04224 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.21439 EPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81689 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100609_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57702 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9262 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE68156_3_v_5_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null Esophagus Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.931151 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 69.318 LRRC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32714 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.872545 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100363_TCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.68459 MMACHC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.338 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27129 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.843513 GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.983951 CYP27B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06259 H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ICC10 DepMap CRISPR Gene Dependency 1.0 4.68778 GSE235066_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.162797 neutropenia GWASdb SNP-Disease Associations 1.0 0.769347 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.31777 Small_Intestine-immature enterocyte Tabula Sapiens Gene-Cell Associations 1.0 5.05389 CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1265 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-U3ZH-1126-SM-4DXUG GTEx Tissue Sample Gene Expression Profiles 1.0 0.908949 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4266 GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 1.19261 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null memory GO Biological Process Annotations 2023 1.0 null long-term memory GO Biological Process Annotations 2023 1.0 null METTL26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8065 Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14038 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24493 GSE62292,GSE62295_2_v_0_col4a3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE86507,GSE86509_7_v_1_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Suprageniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06293 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78141 GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20436 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72303 RELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46465 Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC3H8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02349 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 H3K36me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MIXL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31527 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z4-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69747 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE201239_0_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null AHR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.8502 SU-DHL-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03827 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.65 SMAD4-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE130715_2_v_3_budesonide_human RummaGEO Drug Perturbation Signatures 1.0 null orbital frontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.29292 KLF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21444 hsa-miR-320c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles 1.0 1.19874 PAXBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79467 mediodorsal nucleus of thalamus_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00816 GSE226115,GSE226116_1_v_0_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null medial amygdala, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10467 GTEX-SNOS-1226-SM-4DM5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.32311 HEY DepMap CRISPR Gene Dependency 1.0 8.03522 GTEX-XAJ8-0526-SM-47JYK GTEx Tissue Sample Gene Expression Profiles 1.0 2.0831 GSE248634_1_v_0_gnas_human RummaGEO Gene Perturbation Signatures 1.0 null CETN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00945 H3K36me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAPK14_knockout_14_GDS2693 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.2029 GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 PAPLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39878 ENSG00000286190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0636 GSE245390_2_v_1_acss2_mouse RummaGEO Gene Perturbation Signatures 1.0 null gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null AFF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30355 ZBTB32 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3162 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37714 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865297 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2791 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 0.939291 Cervix - Ectocervix GTEx Tissue Gene Expression Profiles 2023 1.0 4.90764 GTEX-O5YV-0006-SM-2I5GX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.927834 Gastrointestinal cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HJ-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPL-0126-SM-2HMJ7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.914479 TIGD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75784 GTEX-POMQ-0826-SM-3P61H GTEx Tissue Sample Gene Expression Profiles 1.0 1.39535 GSE168807_0_v_7_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null FAAP100 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82428 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HLA-B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5514 GSE154464_1_v_2_cdk6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Longissimus thoracis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.51712 Waardenburg syndrome type 2A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.422 TM2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53981 THAP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87073 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.39335 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7839 hsa-miR-500b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE131161_1_v_0_rarres1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null YAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40189 WSU-NHL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61672 C10orf105 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30867 SW948 CCLE Cell Line Gene Expression Profiles 1.0 1.42112 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148066,GSE157787_11_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02497 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850945 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.4685 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MR-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3611 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40092 r7 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36435 MRPS28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30576 Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10868 bonemarrow_6b HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null EIF4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47933 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14719 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10064 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.844613 hsa-miR-3977 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75745 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887738 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 ESX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50375 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.8783 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Interanteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98286 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4986 Taenia tecta, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13053 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21157 E2F4 ENCODE Transcription Factor Targets 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0443 colon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.843983 PKMYT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56874 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles 1.0 1.84082 Peeling skin syndrome 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null r1 part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42152 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18849 r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38572 GSE244072_10_v_9_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.20027 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24782 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX20-22080862-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-X5EB-1626-SM-4E3IV GTEx Tissue Sample Gene Expression Profiles 1.0 2.25374 MRPS30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50904 MFE319 DepMap CRISPR Gene Dependency 1.0 3.57428 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.017 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-VJYA-1026-SM-4KL21 GTEx Tissue Sample Gene Expression Profiles 1.0 0.938242 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPF39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9343 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.97985 TBX20-22328084-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE240439_1_v_3_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null C5orf22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88778 GSE145215_0_v_1_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.90415 C19orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.05957 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles 1.0 1.56341 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 hsa-miR-21 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 abnormality of myeloid leukocytes GWASdb SNP-Phenotype Associations 1.0 0.20296 GTEX-Q734-1026-SM-48U16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83649 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1463 CCLE Cell Line Gene Expression Profiles 1.0 1.67664 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 1.02731 Small_Intestine-mature enterocyte Tabula Sapiens Gene-Cell Associations 1.0 0.591311 JHUEM1 DepMap CRISPR Gene Dependency 1.0 4.37626 KMOE-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12285138-13059_2025_3667_MOESM3_ESM.xlsx-HT-29_SMAD4_correction-Unnamed_4_SMAD4 Rummagene Transcription Factor Associations 2026 1.0 null Primary somatosensory area, barrel field Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07171 plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.302546 lateral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20135 GSE219195_0_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null skbr3 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 CRYZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20985 SEC14L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27691 ISCU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00351 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46387 GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles 1.0 0.947485 Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.8416 VDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2256 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles 1.0 1.41837 TXNIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30746 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.02404 dorsolateral prefrontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.941358 SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.6593 SRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67064 RABL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25272 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21601 GSE154464_0_v_3_cdk6_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null Psoas_Muscle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.987935 BFTC-909 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null NFE2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01562 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22985 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00288 DOTC2-4510 COSMIC Cell Line Gene Mutation Profiles 1.0 null Intramuscular adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.263 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95357 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 HEPG2 CCLE Cell Line Gene Expression Profiles -1.0 -1.76063 NDUFA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21482 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1999 RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.38 MSRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86474 Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE215849_2_v_1_muc1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K36me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835311 K029AX CCLE Cell Line Gene CNV Profiles -1.0 -1.58769 GTEX-TMMY-0226-SM-33HBA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.933333 PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K36me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mood disorder GWASdb SNP-Disease Associations 1.0 0.273819 NOP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.64034 METTL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3098 SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-T5JC-0001-SM-3NMAK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14832 ILKAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09354 Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 55.6063 PXMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04878 BCAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27404 hsa-miR-1249 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles 1.0 1.07867 GTEX-SN8G-0001-SM-3NM8L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24428 GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 1.40381 GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 CSTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1697 GSE157777_2_v_3_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7764 488395315_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6109 GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877932 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938066 GSE154464_0_v_2_cdk6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0963 hsa-miR-4659a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null DYNC1LI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8316 HLF CCLE Cell Line Gene CNV Profiles 1.0 1.40593 HS578T CCLE Cell Line Gene Expression Profiles -1.0 -1.46683 bonemarrow_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4636-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.851708 ZZZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0079 ZNF737 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84174 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99055 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24171 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SLC24A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41991 GTEX-OOBK-0625-SM-3LK5P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835456 GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1931 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11631 GTEX-QEG5-0226-SM-2I5GI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.849444 GSE184902_4_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null MFAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9641 LK2 CCLE Cell Line Gene Expression Profiles -1.0 -1.51455 RAB11FIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30184 Taenia tecta, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17873 BICR78 DepMap CRISPR Gene Dependency 1.0 2.4199 KYM1 DepMap CRISPR Gene Dependency 1.0 9.05028 H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TKQ2-1326-SM-4DXT9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42234 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.58978 GTEX-WFON-1126-SM-4LVMA GTEx Tissue Sample Gene Expression Profiles 1.0 1.26269 NSMCE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33054 layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34802 GALR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10018 core part of DTg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41414 TIM23 mitochondrial import inner membrane translocase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.868 bone marrow HPA Tissue Gene Expression Profiles -1.0 -1.7811 TAF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33434 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68642 PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62431 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865975 ACADSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15865 superficial stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69718 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.27914 NEUROD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00161 GLDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37544 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91657 central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83768 Skeletal muscle satellite cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33072 GSE120595_0_v_1_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ANKIB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07576 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.875406 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 r6 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28363 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE210655_3_v_7_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null NLGN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1096 Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0571 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE126219_0_v_1_haloperidol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-VJYA-0726-SM-4KL1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834517 ventral premammillary nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2046 TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.3356 NCIH661 CCLE Cell Line Gene CNV Profiles 1.0 1.85125 GSE174498,GSE174500_0_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16686 KYSE30 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 PCBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22196 NAA30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39218 GTEX-R55D-1826-SM-48FEF GTEx Tissue Sample Gene Expression Profiles 1.0 1.25699 RERFLCAI CCLE Cell Line Gene CNV Profiles -1.0 -1.82254 DDX19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27055 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.41346 TRAPPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20013 GTEX-QXCU-0126-SM-2TC5Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.98304 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles 1.0 1.62298 NDUFS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38609 MCRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52296 MAFK ENCODE Transcription Factor Targets 1.0 null GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.946185 FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72823 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51215 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0901 GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.3333 Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-320a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-U4B1-0826-SM-4DXTW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.837541 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles 1.0 0.878381 PAPOLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.22373 ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0564 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12174 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16782 Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55696 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2129 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6724 GSE148692,GSE148695_2_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_7574_KO_SF3B1_SRP342911 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.17854 RAD21 ENCODE Transcription Factor Targets 1.0 null abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.253135 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1636 USP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44717 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61672 r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41414 CARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83777 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9296 SPACA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66914 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.931566 primary motor cortex (area M1, area 4)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5234 GTEX-XMK1-2426-SM-4B66I GTEx Tissue Sample Gene Expression Profiles 1.0 0.859218 FLII CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15201 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20096 LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.91087 Sarcoma_SARC_TCGA-KD-A5QU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35083 WWC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23581 GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles 1.0 1.1181 GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 oculomotor nucleus, Edinger-Westphal subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17026 pituitary GTEx Tissue Gene Expression Profiles 1.0 0.870865 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.941623 GSE148692,GSE148695_7_v_3_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE210655_3_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null CAMKV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47163 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0 SW 1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0917 central gray substance of midbrain, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.947949 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.34347 GTEX-PX3G-0126-SM-2I3EN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.952077 H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16808 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.913073 GFI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07313 GSE158197_2_v_3_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE182180_1_v_2_secretin_human RummaGEO Drug Perturbation Signatures -1.0 null GTPBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21053 RPS24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02775 principal sensory nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22598 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46865 spleen HPA Tissue Protein Expression Profiles -1.0 -0.74109 hsa-miR-362-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GSE244072_4_v_6_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE72895,GSE72896_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95795 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15298 GSE112860_0_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE128099,GSE128159_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.1263 hsa-miR-371b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 FOXRED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14238 anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.86531 medial group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21574 hsa-miR-4760-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 GSE152432_5_v_2_zrsr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-1726-SM-46MVO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10117 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null lateral parabrachial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51872 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39264 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04329 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 PK59 CCLE Cell Line Gene CNV Profiles -1.0 -1.51802 GSE158743_1_v_2_nfkbia_human RummaGEO Gene Perturbation Signatures -1.0 null GSE180951_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null KMS34 CCLE Cell Line Gene CNV Profiles -1.0 -1.4599 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.2255 GSE120595_5_v_1_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE48812_7_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null ATXN2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86719 CCFSTTG1 CCLE Cell Line Gene Expression Profiles 1.0 1.51335 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.0745 GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles 1.0 1.73644 RNF122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01127 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3183 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4196 MYCL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95495 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027435 RAVER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27877 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.857527 Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 1.0 2.30435 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00304 CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11875 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TNKS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47156 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.88279 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993054 ISTMES1 CCLE Cell Line Gene CNV Profiles -1.0 -2.59393 Lung squamous cell carcinoma_LUSC_TCGA-90-7767-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFYVE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99046 GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920222 DCTN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77771 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE235945_1_v_0_pikfyve_mouse RummaGEO Gene Perturbation Signatures 1.0 null CLIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96199 CCDC87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6947 esophagus HPA Tissue Protein Expression Profiles -1.0 -2.0052 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46397 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.107 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.831549 WM35 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K36me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AIF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74301 Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3287 CCDC153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52988 PATU8902 DepMap CRISPR Gene Dependency 1.0 3.20285 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9761 Perturb_7427_KD_PTBP1/PTBP2_SRP059242 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.61132 ADAM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80357 cellular_component GO Cellular Component Annotations 2015 1.0 null ANKRD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15912 NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.4522 EIF4EBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69386 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles 1.0 1.41685 IZUMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07647 ZNF420 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43948 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE136622_0_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures -1.0 null FTL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75331 GSE196012_1_v_0_brap_mouse RummaGEO Gene Perturbation Signatures 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32881 colonrectum_f HPA Tissue Sample Gene Expression Profiles 1.0 0.846419 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null CK1G2 Kinase Library Serine Threonine Kinome Atlas 1.0 null GSE180200,GSE180201_15_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.0743 PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null PEG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40482 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 1.14512 central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21409 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles 1.0 1.42401 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles 1.0 0.936044 Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16443 Ventral tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22146 SMAD2/3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RUNX1-22412390-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LYRM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02542 SMARCA4 ChEA Transcription Factor Targets 1.0 null TOP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44202 Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10839 GTEX-X62O-0008-SM-46MU5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05688 GTEX-U3ZM-1126-SM-4DXUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.974295 BICR22 DepMap CRISPR Gene Dependency 1.0 2.16006 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33312 SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1R18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66802 outer CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.871707 depression GWASdb SNP-Phenotype Associations 1.0 0.348868 mantle zone of AHy Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28303 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GYS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7394 GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.967113 colonrectum_b HPA Tissue Sample Gene Expression Profiles 1.0 0.830815 GTEX-SIU7-0001-SM-3NMAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.887838 Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16509 GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90991 GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles 1.0 0.897093 MHH-NB-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910053 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE174383_6_v_0_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null muscle GTEx Tissue Gene Expression Profiles 1.0 0.983884 GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06677 membrane part GO Cellular Component Annotations 2015 1.0 null FBXO46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94406 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.64 GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07406 RFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92393 Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37878 GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15175 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24043 OAW42 CCLE Cell Line Gene Expression Profiles -1.0 -1.9837 DEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73116 NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18432 HTR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25727 GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.926144 Small_Intestine-paneth cell of epithelium of small intestine Tabula Sapiens Gene-Cell Associations 1.0 2.58948 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4977-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41124 Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colonic cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98286 small intestine GTEx Tissue Gene Expression Profiles 1.0 1.7397 Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57503 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28809 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9907 GSE48812_0_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles 1.0 1.19256 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53452 TCF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19773 GSE151090_5_v_4_verteporfin_human RummaGEO Drug Perturbation Signatures -1.0 null CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03232 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.831549 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992011 GSE149000_2_v_0_cyp3a5_human RummaGEO Gene Perturbation Signatures 1.0 null GSE235066_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.8322 SMRT-22465074-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20232 SW579 CCLE Cell Line Gene CNV Profiles 1.0 1.95381 Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DCAKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95211 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49572 endometrium HPA Tissue Protein Expression Profiles -1.0 -1.09537 Perturb_1432_KO_Kmt2c_SRP283007 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.89991 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21064 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17514 hsa-miR-3614-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ABCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17939 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TNPO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.71068 UTP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25922 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33202 MTIF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24555 NCIH1355 DepMap CRISPR Gene Dependency 1.0 5.26093 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81881 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02754 METTL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84647 CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925648 Perturb_1436_KO_Kmt2c_SRP283007 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.18796 EP400 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73985 GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 smallintestine_4d HPA Tissue Sample Gene Expression Profiles 1.0 1.34556 EP300 ENCODE Transcription Factor Targets 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-4436b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GOLM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.30148 Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77599 CAL-12T COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null MAJIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83239 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.867524 PDCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27392 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24413 GTEX-R55C-1126-SM-48FCJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15662 CTCF_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199092_3_v_0_ddx5_human RummaGEO Gene Perturbation Signatures 1.0 null TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2182 Parataenial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.56379 Fetal_Intestine_Small Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.56058 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34915 rostromedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6107 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 2.11642 GTEX-P78B-1826-SM-3P5YX GTEx Tissue Sample Gene Expression Profiles 1.0 0.862449 SNU61 CCLE Cell Line Gene Expression Profiles 1.0 1.55818 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 0.913764 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23916 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3467 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Small_Intestine-enterocyte of epithelium of small intestine Tabula Sapiens Gene-Cell Associations 1.0 4.98729 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 SMAD3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 0.853072 SFXN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78337 Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23619 RBM33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13531 pyramidal cells of caudal CA4 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872419 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14056 Perturb_15826_OE_Nrf2_SRP291725 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.42012 PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles 1.0 2.61974 GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 cervix, uterine HPA Tissue Protein Expression Profiles -1.0 -0.74109 Large_Intestine-large intestine goblet cell Tabula Sapiens Gene-Cell Associations 1.0 0.724522 Primary somatosensory area, nose Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12777 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78832 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Frontal pole, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01514 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826637 G402 DepMap CRISPR Gene Dependency 1.0 2.74864 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles 1.0 2.78584 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98823 GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles 1.0 1.32692 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EXOSC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25352 ZNF330 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17699 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.892355 GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 FAU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03947 orbital frontal cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11916 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64461 GSE169155_1_v_2_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U3ZN-2126-SM-4DXU1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.97874 PKIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45742 Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2706 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31923 PPP6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91081 viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.926905 alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE135352_0_v_1_napabucasin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44561 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112174_5_v_7_runx1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DNA ligase IV deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.238 H9 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WFG7-1526-SM-4LVMG GTEx Tissue Sample Gene Expression Profiles 1.0 1.25616 GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922572 CENPP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72022 GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924053 RNF181 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36481 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39341 STAT3 ENCODE Transcription Factor Targets 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.985742 lateral group of nuclei, left, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.67518 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFG7-1726-SM-4LVME GTEx Tissue Sample Gene Expression Profiles 1.0 1.66986 GTEX-OOBK-0126-SM-2YUND GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884116 Glycogen storage disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.202 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09644 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH684 CCLE Cell Line Gene Expression Profiles 1.0 2.65497 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.7708 COLO205 CCLE Cell Line Gene Expression Profiles 1.0 2.13012 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831458 NMB DepMap CRISPR Gene Dependency 1.0 5.84046 TIGD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2567 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1717 VASH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57152 hsa-miR-338-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 r9 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04698 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887738 SLC35B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02703 CA SKI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.980719 GSE152432_3_v_0_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.856771 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.9262 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 NAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1255 hsa-miR-548ae TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 496100564_TCx_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.50925 PIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09375 B4GALT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30036 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GU-06A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.884266 DUSP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31864 ZNF689 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1316 Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00181 TT CCLE Cell Line Gene CNV Profiles 1.0 1.39894 SKIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08281 NSA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 PAM complex, Tim23 associated import motor COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.933 Primary somatosensory area, mouth, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03292 Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 48.0536 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15935 Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25864 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CHID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55783 GTEX-W5WG-2426-SM-4LMI6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45319 ANLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81804 Piebaldism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 NPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51951 GTEX-POYW-0526-SM-2XCEY GTEx Tissue Sample Gene Expression Profiles 1.0 1.90903 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18349 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.860862 primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.979601 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07851 NAPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03538 hsa-miR-4772-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997132 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896019 GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles 1.0 0.891577 TTC30B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84385 KLF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5716 Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33275 NALM-6 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 2.27429 MEX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78147 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.912759 BICR16 DepMap CRISPR Gene Dependency 1.0 6.51855 TAPBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50104 PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null FYTTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14912 SNU1079 CCLE Cell Line Gene Expression Profiles -1.0 -2.18909 ZNF596 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33626 Lateral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05867 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMY1 DepMap CRISPR Gene Dependency 1.0 3.11005 amygdaloid complex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08919 BICR31 CCLE Cell Line Gene CNV Profiles 1.0 1.61519 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SW403 CCLE Cell Line Gene Expression Profiles 1.0 1.90632 Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles 1.0 1.86888 Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4797 cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1198 primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05637 Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.7626 HT55 CCLE Cell Line Gene Expression Profiles 1.0 1.39525 KMT2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53446 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19601 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ2-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12798 NOVA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99918 lateral reticular nucleus (principal part) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34144 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.6322 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.77914 CNOT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70434 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7318 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944816 Perturb_5549_KO_Wdr72_SRP353473 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.57867 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40917 colon_8b HPA Tissue Sample Gene Expression Profiles 1.0 0.846495 Primary somatosensory area, trunk, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34449 Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.821641 GTEX-XUZC-1426-SM-4BRV3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.8115 lung_4d HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 ZNF281 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11293 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08558 LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE70935_2_v_4_cyfip1_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMIM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.24732 GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GSE169155_5_v_4_acetaminophen_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.944806 Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mitochondrial pyruvate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.342 NCI-H2085 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.826719 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.83301 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15846 Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-302a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 TMOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11651 GTEX-WFON-1426-SM-4LVMT GTEx Tissue Sample Gene Expression Profiles 1.0 1.67146 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3829 MFHAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46759 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4573 GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.923696 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.49845 GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 lateral medullary reticular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896785 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03087 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.852704 dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.981294 MAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38198 LMX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46887 GSE158632_2_v_4_oxyquinoline_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles 1.0 0.93971 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.97287 Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null KNTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27656 ASXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23051 hsa-miR-520d-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 RFXAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47476 SMIM10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33498 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.998682 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.9303 LRFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.24042 DTX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35826 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 0.947901 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 PKNOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96209 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46493 COL9A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47235 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13672 GSE201309_5_v_8_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00853 Lung adenocarcinoma_LUAD_TCGA-50-5936-01A-11R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 EHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.37963 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.946249 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.848784 KDM4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7052 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 GTEX-S4Q7-0008-SM-3NM8A GTEx Tissue Sample Gene Expression Profiles 1.0 0.840222 JJN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null duodenum HPA Tissue Gene Expression Profiles 1.0 1.40476 BBIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.83871 Tegmental reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2489 GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles 1.0 1.50193 Sigmoid_Colon Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.06514 hsa-miR-4429 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 KYSE70 CCLE Cell Line Gene CNV Profiles 1.0 1.42684 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE189172,GSE189173_2_v_0_traf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAL12T CCLE Cell Line Gene Expression Profiles -1.0 -1.89393 PPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11082 HUH7 CCLE Cell Line Gene CNV Profiles 1.0 2.20219 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE152432_6_v_0_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4659b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.995405 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2267 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25787 inner SZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.953173 HCC1588 CCLE Cell Line Gene Expression Profiles 1.0 2.28185 SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6426 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.948157 GTEX-XUW1-1926-SM-4BOP1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964628 GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 1.8597 mcf7 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 NCBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54547 Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P1-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIB ChEA Transcription Factor Targets 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 BRD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.38577 HUS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28316 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE92434_1_v_0_ebf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE157777_1_v_0_foxa3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4P3-1226-SM-4AD4Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.00778 CCM2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74786 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 leukopenia GWASdb SNP-Disease Associations 1.0 0.384634 GSE139455_2_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null HAUS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77891 Lung squamous cell carcinoma_LUSC_TCGA-85-A50M-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC28B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02859 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07401 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.745 intestine TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12506 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.54606 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24086 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3942 PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1023 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2848 inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.27034 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202310_1_v_0_ube3d_mouse RummaGEO Gene Perturbation Signatures 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.81287 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA2-22383799-G1ME-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.899482 hsa-miR-548am TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.27932 GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.843662 hsa-miR-590-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.43731 GSE77108_0_v_2_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-520b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4722-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 PRDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39791 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.78157 GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles 1.0 3.07718 GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.931798 placenta_3a HPA Tissue Sample Gene Expression Profiles -1.0 -0.843156 SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4729 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 MDH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10535 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.051 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39264 GSE212312_2_v_3_fbxw7_human RummaGEO Gene Perturbation Signatures -1.0 null GSE157594_3_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A5KG-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-1826-SM-2S1Q2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03491 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3825 GTEX-XBED-1426-SM-4AT4G GTEx Tissue Sample Gene Expression Profiles 1.0 2.24001 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ESRRG_ESRRG Rummagene Transcription Factor Associations 2026 1.0 null lateral periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6962 RPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72383 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55G-1226-SM-48FDC GTEx Tissue Sample Gene Expression Profiles 1.0 1.92122 Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.989757 Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PARD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76956 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987107 Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76102 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles 1.0 0.960213 GSE224294_1_v_2_ngly1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 KARPAS-422 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 DBNDD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73797 GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06988 Primary somatosensory area, trunk Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07935 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 496100356_TCx_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19777 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 U2AF2_02_105 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.27302 GTEX-XOT4-0626-SM-4B66L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903619 cochlear nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14629 hsa-miR-372 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9359 ADGRA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28155 MG-63 COSMIC Cell Line Gene CNV Profiles 1.0 2.64759 GTEX-OIZH-1426-SM-3NB1O GTEx Tissue Sample Gene Expression Profiles 1.0 0.946114 MYC-27129775-CHIP-SEQ-CORNEA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17514 Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17873 FXYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90273 cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38921 NCIH1573 DepMap CRISPR Gene Dependency 1.0 3.41802 TCEAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49471 GSE169155_1_v_0_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMVK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92211 lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48689 CAL27 CCLE Cell Line Gene CNV Profiles -1.0 -1.71288 NCI-H1648 COSMIC Cell Line Gene Mutation Profiles 1.0 null CIDEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73519 GTEX-WFJO-0926-SM-4LVM2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94588 GSE178227_1_v_2_tet1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13812 NCIH2405 CCLE Cell Line Gene CNV Profiles -1.0 -1.59818 GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 0.87378 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.875036 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null KCTD20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49307 GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SLC35C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25103 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847512 GSE110440_2_v_3_rad21_mouse RummaGEO Gene Perturbation Signatures 1.0 null LSM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46751 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-0826-SM-4B64N GTEx Tissue Sample Gene Expression Profiles 1.0 1.30025 CDKN2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18954 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.5529 posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5677 RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.57053 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles 1.0 0.939546 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RU-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 13.8088 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 HOXB2::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.062 CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-0926-SM-3P5ZQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27344 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 MRK-NU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887738 GSE217115_3_v_0_alectinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SHOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02157 GSE201309_1_v_8_matrine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 FTC238 CCLE Cell Line Gene CNV Profiles -1.0 -2.17558 DPH7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28532 PTPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6397 Sarcoma_SARC_TCGA-DX-A6B8-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38671 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null GNE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67782 interanterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.19887 Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25651 NIX_Deficiency_GDS2630_655_mouse_Spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GADD45A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72031 HCC-33 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 hsa-miR-302c TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ZNF718 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29376 PMC10859382-41392_2024_1740_MOESM3_ESM.pdf-13-JUND_JUND Rummagene Transcription Factor Associations 2026 1.0 null 496100375_FWM_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0315 FU-OV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles 1.0 2.87379 dorsolateral prefrontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37946 BRMS1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73054 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04688 abnormality of neutrophils GWASdb SNP-Phenotype Associations 1.0 0.386039 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.877415 NCIH1838 CCLE Cell Line Gene CNV Profiles 1.0 1.70812 ZC3H11A_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6241 FERD3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82883 GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles 1.0 1.0836 hsa-miR-4803 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25405 DSTYK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23083 outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26824 GTEX-QV44-0008-SM-447AX GTEx Tissue Sample Gene Expression Profiles 1.0 1.00925 TE-441-T COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72662 ZC3H11A ENCODE Transcription Factor Targets 1.0 null ASPC1 CCLE Cell Line Gene Expression Profiles 1.0 2.05333 r2 part of median raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09594 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.0986 subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.07362 H2AZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71811 LDB1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PAFAH1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82857 hsa-miR-520e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GSE185944_0_v_1_pth1r_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRG_RXRG Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28303 KCTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41157 DAOY CCLE Cell Line Gene CNV Profiles -1.0 -1.7235 hsa-miR-520c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Calpain complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.536 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AMOT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54503 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844551 GTEX-P4PP-1526-SM-3P61M GTEx Tissue Sample Gene Expression Profiles 1.0 1.07302 placenta_6c HPA Tissue Sample Gene Expression Profiles -1.0 -0.897776 Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glycogen metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.201 RTL8A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3485 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.871681 hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5635 hsa-miR-4711-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01093 KDM5A ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6665-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.994 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6246 GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.2734 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0743 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13142 bonemarrow_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.38407 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831458 GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03236 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4901 HNRNPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54526 ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71598 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26043 abnormal leukocyte count GWASdb SNP-Phenotype Associations 1.0 0.386039 GSE156115_2_v_1_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF749 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50837 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE182179_0_v_4_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null inner CP in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03767 SPDEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70758 FBXW4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43182 GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4603 Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bed nucleus of the external capsule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07503 SDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42023 hsa-miR-4452 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.849836 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.439043 OLFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05882 POLR2A ENCODE Transcription Factor Targets 1.0 null TTC709 DepMap CRISPR Gene Dependency 1.0 5.01034 STX12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71861 KASUMI1 DepMap CRISPR Gene Dependency 1.0 18.8632 GSE172201_1_v_0_zkscan3_human RummaGEO Gene Perturbation Signatures 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral (parvicellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21601 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.4672 NKG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62527 GALK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37315 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.977925 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19688 DNAJC28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59578 H3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98491 GSE101537_4_v_2_neurog3_mouse RummaGEO Gene Perturbation Signatures -1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null GTEX-PLZ5-1126-SM-3P613 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29409 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 hel HPA Cell Line Gene Expression Profiles -1.0 -0.826749 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05352 superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32241 GTEX-OIZI-0008-SM-2XCFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.19062 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.64806 KASUMI1 CCLE Cell Line Gene CNV Profiles 1.0 1.76758 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZKSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84941 ARHGAP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37575 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2421 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 0.849417 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02365 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5956 GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0523 NIX_Deficiency_GDS2630_160_mouse_spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZNF622_02_108 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.75489 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3934 GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures 1.0 null RCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45579 CA-SKI COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.87338 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.70573 duodenum_4c HPA Tissue Sample Gene Expression Profiles 1.0 1.63518 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42816 Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11819 IQSEC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63768 Pou5f1::Sox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 56.8384 lateral nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14516 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.80641 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67593 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37225 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CHEK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18123 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08874 SAYSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80623 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20018 GSE234340_10_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.3668 TEX45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14495 GSE250560_1_v_0_foxo1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06462 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.895406 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100582_HIP_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.00017 PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2 Rummagene Transcription Factor Associations 2026 1.0 null POLR2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98278 GTEX-QMRM-1226-SM-447C6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01692 GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H250 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles 1.0 1.08344 SNCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25335 caudal linear (raphe) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3575 hsa-miR-4310 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56981 SMC3 ENCODE Transcription Factor Targets 1.0 null GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.894127 GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68412 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.201 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.76893 SASS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.5384 GSE148695,GSE167281_2_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.531 LCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57418 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles 1.0 1.69121 ZC3H11A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoglycan complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.625 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5856 medial amygdala, posterodorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12746 Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205556_2_v_0_bexarotene_human RummaGEO Drug Perturbation Signatures 1.0 null thyroid_5a HPA Tissue Sample Gene Expression Profiles -1.0 -0.911021 GSE112860_0_v_8_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.7841 LS513 CCLE Cell Line Gene Expression Profiles 1.0 1.7687 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.48442 CSDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57874 deep layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11633 anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.1097 llcmk2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.871 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61915 Striated muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.729 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 0.828926 Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5664 SPPL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06208