association dataset threshold value standardized value GSE119978,GSE180930_6_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles 1.0 0.836574 GSE210580_3_v_2_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A83I-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal involuntary movement MPO Gene-Phenotype Associations 1.0 null GAMG Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.98867 ChIP_H3K27me3_17603471_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-133a TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 KANSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46733 K562_Ramelteon_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0205503 K-562 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.726097 Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null limb grasping MGI Mouse Phenotype Associations 2023 1.0 null Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.993 GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03239 hsa-miR-548e TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.968068 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12266 Bach1::Mafk JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0526 GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 1.32447 GTEX-S341-1926-SM-3K2BA GTEx Tissue Sample Gene Expression Profiles 1.0 1.12029 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43917 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.969909 HCC1195 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 TCCSUP DepMap CRISPR Gene Dependency 1.0 2.88394 Lapatinib ditosylate_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0133902 efo21 HPA Cell Line Gene Expression Profiles 1.0 1.01599 hsa-miR-506 TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 Human - Fetal Development - L2 - Heart-SATB2_LRRC7 positive cells HuBMAP Azimuth Cell Type Annotations 1.0 null Body mass index GWAS Catalog SNP-Phenotype Associations 1.0 0.165905 Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REL MotifMap Predicted Transcription Factor Targets 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-16-NFIA_NFIA Rummagene Transcription Factor Associations 2026 1.0 null neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.717882 GSE77795_2_v_1_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.09732 SH-4-54 DeepCoverMOA Drug Mechanisms of Action 1.0 0.21 LN235 DepMap CRISPR Gene Dependency 1.0 9.16356 hsa-miR-452 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Nephrotic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 GTEX-QDT8-0011-R8A-SM-32PKE GTEx Tissue Sample Gene Expression Profiles 1.0 1.07771 brain_a HPA Tissue Sample Gene Expression Profiles 1.0 3.15547 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 1.84289 GSE94814_2_v_3_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null MCEE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41933 Hypertension risk in short sleep duration GWAS Catalog SNP-Phenotype Associations 1.0 0.389385 Focal segmental glomerulosclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 RASSF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90069 cell junction GO Cellular Component Annotations 2015 1.0 null salivary gland HPA Tissue Protein Expression Profiles -1.0 -0.865861 GTEX-TML8-1626-SM-32QOO GTEx Tissue Sample Gene Expression Profiles 1.0 0.902222 GSE126127_0_v_1_prmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.096176 hsa-miR-3129-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85476 Disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.88212 GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.26674 GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.838899 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11015 Dendritic tree COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.027 hepg2 HPA Cell Line Gene Expression Profiles -1.0 -0.869367 FOXA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07229 TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 67.9187 Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.940169 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46998 limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62763 hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H2BK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02322 cell junction COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.46639 splice GeneRIF Biological Term Annotations 1.0 null RORA_1 MotifMap Predicted Transcription Factor Targets 1.0 null frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.855611 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Presynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.044 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null yeast Phosphosite Textmining Biological Term Annotations 1.0 null Riluzole hydrochloride_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0240443 Prostate adenocarcinoma_PRAD_TCGA-KC-A4BV-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFDN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3509 GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null premature death MGI Mouse Phenotype Associations 2023 1.0 null LPAR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05007 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUP-T1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.63414 cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940762 synapses GeneRIF Biological Term Annotations 1.0 null CA1 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57023 MCF7_BREAST CCLE Cell Line Proteomics 1.0 2.55491 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.7542 NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 2.33618 Attention Deficit Disorder DisGeNET Gene-Disease Associations 1.0 null abnormal body weight MPO Gene-Phenotype Associations 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.937488 modulates GeneRIF Biological Term Annotations 1.0 null abnormal response to novel object MGI Mouse Phenotype Associations 2023 1.0 null GSE126127_0_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHSB-0326-SM-3LK6K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36645 Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal short-term spatial reference memory MGI Mouse Phenotype Associations 2023 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.36915 ABCC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33876 GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles 1.0 0.944975 Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMRC20_KIDNEY CCLE Cell Line Proteomics 1.0 2.46837 MZ in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10313 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21251 Simotinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0306189 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4893-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07233 hsa-miR-548n TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.403637 FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7583 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211983_1_v_2_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC7069022-Table_1.xlsx-MYCN_Cor_Microarray_Analysis-GENE_MYCN Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XMK1-0926-SM-4B66X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24526 neurotransmitter receptor transport, endosome to plasma membrane GO Biological Process Annotations 2023 1.0 null basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hacat HPA Cell Line Gene Expression Profiles 1.0 1.49561 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6869-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basolateral plasma membrane GO Cellular Component Annotations 2025 1.0 null H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CHP126 CCLE Cell Line Gene Expression Profiles 1.0 1.41178 NR5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26798 Small Intestine - Terminal Ileum GTEx Tissue Gene Expression Profiles 2023 1.0 1.95879 GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 1.29032 GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56534 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63198 organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047278 abnormal postnatal growth/weight/body size MPO Gene-Phenotype Associations 1.0 null GSE126345_11_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perirhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.834 ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 94.4341 hsa-miR-1283 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824178 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07216 GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 1.97569 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03393 synucleinopathy GWASdb SNP-Disease Associations 1.0 0.808756 ATP2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17792 NR3C1-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null GTEX-RWS6-0226-SM-2XCA9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06295 Cytarabine (hydrochloride)_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0136588 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.858438 Phenylephrine (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0276378 PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null dendritic spine head COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.3752 artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.00232 Perturb_3666_KO_FASTKD_SRP277516 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.26594 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.83458 Intralaminar nuclei of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08202 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54781 DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE210101,GSE210114_6_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GSE198165,GSE198166_0_v_1_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70949 GTEX-W5X1-2626-SM-4LMI8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860149 C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13652 Binimetinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0325069 K562_Prednisone_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0210652 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06055 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03849 kidney cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062718 Meloxicam_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0113446 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10343 LOXIMVI CCLE Cell Line Gene Expression Profiles 1.0 1.75448 GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 1.19311 STXBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78572 membrane Phosphosite Textmining Biological Term Annotations 1.0 null hsa-miR-3133 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 JARID2 ChEA Transcription Factor Targets 1.0 null Perturb_3849_KD_TGM2_SRP194250 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.33314 Pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.651 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null PMC10617732-pgen.1010988.s017.xlsx-Enrichments_Fig_5_S11_A-ATF2_ATF2 Rummagene Transcription Factor Associations 2026 1.0 null Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.468 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51035 GP2D CCLE Cell Line Gene Expression Profiles -1.0 -2.3244 JHH-4 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.93946 Adherens junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 upper (rostral) rhombic lip_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.832558 posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.837321 adhesion Phosphosite Textmining Biological Term Annotations 1.0 null MAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74814 hsa-miR-1179 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.536183 calcium-calmodulin-dependent-protein-kinases Phosphosite Textmining Biological Term Annotations 1.0 null PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10424 GSE218580_1_v_0_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null TF1 CCLE Cell Line Gene CNV Profiles 1.0 1.79414 NCI-H1105 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TBR1_TBR1 Rummagene Transcription Factor Associations 2026 1.0 null body height GAD Gene-Disease Associations 1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.3243 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 2.89441 NR3C1-23031785-PC12-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.957 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null YWHAB Hub Proteins Protein-Protein Interactions 1.0 null cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.094918 lymphnode_4a HPA Tissue Sample Gene Expression Profiles -1.0 -1.03744 GTEX-X4XX-0011-R4B-SM-46MWL GTEx Tissue Sample Gene Expression Profiles 1.0 0.960969 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19649 OLIG2 ChEA Transcription Factor Targets 1.0 null PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2 Rummagene Transcription Factor Associations 2026 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.915236 TUR COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07233 Lonafarnib_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0155506 embryonic stem feeder layer BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.35896 I3C DeepCoverMOA Drug Mechanisms of Action 1.0 0.32 NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null Postsynaptic cytosol COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.754 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.019 NCIH358_LUNG CCLE Cell Line Proteomics 1.0 2.00967 HCC2279 CCLE Cell Line Gene Mutation Profiles 1.0 null SUZ12-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-182 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.923186 UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC7788918-13058_2020_1379_MOESM2_ESM.xlsx-S9-S9_limma_voom_differentially_expressed_genes_ESR1_depleted_recurrences_vs_matched_primaries_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null genomewide GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null microtubule organizing center COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GET4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.16709 abnormal sleep behavior MGI Mouse Phenotype Associations 2023 1.0 null GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 1.06414 hsa-miR-4419b TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.43757 GSE149035_3_v_5_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null GSE113106_2_v_4_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.04585 GSE239541_8_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null K562_PHA-680632_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0176393 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-34a TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3678 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.27582 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35777 EZH2-27304074-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.923729 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03452 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8791 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10479 GTEX-RWS6-0926-SM-47JXE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88125 PANC0203 CCLE Cell Line Gene Mutation Profiles 1.0 null ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12349 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.79347 TMCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92803 Lateral posterior nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09448 OE33 DepMap CRISPR Gene Dependency 1.0 2.13787 Catenin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.354 cytoskeletal part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.887092 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.105504 Indacaterol (maleate)_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0209375 membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-Q2AG-0011-R1A-SM-2HMJI GTEx Tissue Sample Gene Expression Profiles 1.0 1.53495 GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.44003 SBC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null DLGAP2 Pathway Commons Protein-Protein Interactions 1.0 null RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6045 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87544 STAT3 MotifMap Predicted Transcription Factor Targets 1.0 null GSE209911_0_v_1_ncstn_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_4643_KO_Wwc2_SRP151543 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.83801 NOZ DepMap CRISPR Gene Dependency 1.0 4.1728 renal glomerular capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.256902 C33A DepMap CRISPR Gene Dependency 1.0 3.35308 Cytoplasmic vesicle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 white matter of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15787 GSE118077_7_v_2_sprr5_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WEY5-2226-SM-3GILQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.908399 GSE210101,GSE210114_5_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_10045_KD_EIF3D_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.77866 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56473 hsa-miR-4760-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Neutrophil degranulation Reactome Pathways 2024 1.0 null GSE163052,GSE163198_2_v_3_hira_mouse RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.945821 protein localization to postsynapse GO Biological Process Annotations 2023 1.0 null abnormality of body weight GWASdb SNP-Phenotype Associations 1.0 0.360941 GSE210101,GSE210114_0_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0147 GSE211983_0_v_2_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26985 Tetracycline (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.044819 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.90406 Perturb_8474_KO_CTNNB1_SRP137216 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.3558 SOX2 ChEA Transcription Factor Targets 1.0 null cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.731442 Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null Cocaine-Related Disorders CTD Gene-Disease Associations 1.0 2.88009 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YKG1 DepMap CRISPR Gene Dependency 1.0 4.63572 hsa-miR-3714 TargetScan Predicted Conserved microRNA Targets 1.0 0.187098 dendritic spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.25285 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43917 GTEX-WVLH-0011-R5A-SM-3MJFW GTEx Tissue Sample Gene Expression Profiles 1.0 1.81729 Perturb_11962_KO_Tr1_SRP355815 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.28111 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80N-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTF2-20144788-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE217101_0_v_1_mcph1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormal response to novel object MPO Gene-Phenotype Associations 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE195503_3_v_2_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null BHT101 CCLE Cell Line Gene Expression Profiles -1.0 -1.53143 NCI-H847 COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.30667 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6752 GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1577 Meiotic spindle pole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.527 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.801562 excitatory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.636295 abnormal social investigation MGI Mouse Phenotype Associations 2023 1.0 null nphs2 GeneRIF Biological Term Annotations 1.0 null Perturb_15349_KO_TET1/TET2/TET3_SRP251780 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 putamen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09867 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64877 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.119683 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures 1.0 null Plasma membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.551 diaphragm GeneRIF Biological Term Annotations 1.0 null mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34414 Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Type 2 diabetes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31068 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.825731 GTEX-X585-3026-SM-46MWF GTEx Tissue Sample Gene Expression Profiles 1.0 0.915191 GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.50219 abnormal nest building behavior MPO Gene-Phenotype Associations 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null GSE174701_4_v_3_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null HT-29 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.30822 ChIP_EZH2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null HCC78 CCLE Cell Line Gene CNV Profiles 1.0 1.42907 GSE131649_6_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01543 Immune System Reactome Pathways 2024 1.0 null GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881012 cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-607 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Progressive myoclonus epilepsy 4 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.169 Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE129241_3_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE180185_7_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurotransmitter receptors and postsynaptic signal transmission Reactome Pathways 2024 1.0 null HEY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.921 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Psoriasis GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.852288 GTEX-WHSE-3026-SM-3P5ZH GTEx Tissue Sample Gene Expression Profiles 1.0 0.981871 KP-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08596 SUZ12-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10827 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20894 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4777-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.03 asymmetric synapse GO Cellular Component Annotations 2025 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.991672 GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.05675 Sinus node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.628 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.834731 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.99552 GTEX-WWYW-0011-R7A-SM-3NB3H GTEx Tissue Sample Gene Expression Profiles 1.0 1.15237 Narcolepsy DisGeNET Gene-Disease Associations 1.0 null SNU2535 DepMap CRISPR Gene Dependency 1.0 3.07392 act GeneRIF Biological Term Annotations 1.0 null NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nfe2l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.741 postsynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.37796 GTEX-S33H-2326-SM-2XCB3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05432 ZNF236 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43781 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15526 Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.691 Animal cap TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.64 E2A MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-4794 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RH30 CCLE Cell Line Gene Expression Profiles -1.0 -1.54272 GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.21831 HS944T CCLE Cell Line Gene Mutation Profiles 1.0 null glutamate GeneRIF Biological Term Annotations 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.3602 SKA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00537 MAPK1/MAPK3 signaling Reactome Pathways 2024 1.0 null Nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.573 actn4 GeneRIF Biological Term Annotations 1.0 null GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 1.55943 DOV13 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.77644 hsa-miR-15a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 GSE139992_1_v_0_mboat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_4761_KO_DLG2_SRP315088 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.699 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.539 abnormal survival MPO Gene-Phenotype Associations 1.0 null PAR polarity complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.021 IFI6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3094 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.16338 Axon initial segment COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.1396 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02888 GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2836 GTEX-X585-0011-R4B-SM-46MVH GTEx Tissue Sample Gene Expression Profiles 1.0 0.968036 LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SKMEL5_SKIN CCLE Cell Line Proteomics 1.0 2.27108 ES5 DepMap CRISPR Gene Dependency 1.0 2.21036 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.30189 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77196 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7673 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39777 specific granule lumen GO Cellular Component Annotations 2025 1.0 null spleen_3c HPA Tissue Sample Gene Expression Profiles -1.0 -1.03095 SOX9 MotifMap Predicted Transcription Factor Targets 1.0 null GSE126345_2_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_122_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null CAL51_BREAST CCLE Cell Line Proteomics 1.0 7.08033 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.8927 Physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03336 GSE248858_6_v_2_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WH7G-0002-SM-4LVN9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05531 PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07896 Perturb_14533_KO_Ptf1a/Foxa2_SRP111204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 characterization GeneRIF Biological Term Annotations 1.0 null GTEX-RWS6-0008-SM-47JYV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02419 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.720345 Cocaine CTD Gene-Chemical Interactions 1.0 null GLI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0777 Secretory granule lumen COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1376 hsa-miR-485-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null Lamin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.872 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2076 HuP-T3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.87907 cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Ternary complex (LRRC7, CAMK2a, ACTN4) CORUM Protein Complexes 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH7 CCLE Cell Line Gene Mutation Profiles 1.0 null Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.054977 GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.12672 GTEX-RU1J-0326-SM-46MUM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909667 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.881535 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.888076 ZNF717 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52355 synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.01238 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53805 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17216 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98101 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.41607 Mebendazole_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0190871 Innate Immune System Reactome Pathways 2024 1.0 null hsa-miR-449c TargetScan Predicted Conserved microRNA Targets 1.0 0.404082 TCCSUP Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.93093 neurotransmitter receptor transport to postsynaptic membrane GO Biological Process Annotations 2025 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null LY2090314_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0189438 GTEX-S4Q7-1426-SM-3K2B9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.89167 EZH2-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HEC251 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.995409 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4497 synapse part GO Cellular Component Annotations 2015 1.0 null Hypolemmal cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.525 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.844687 caudate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04108 hsa-miR-96 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58747 GSE149442_1_v_0_gdpd3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_3620_KO_SMARCA4_SRP127343 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.98999 CCK81 CCLE Cell Line Gene Mutation Profiles 1.0 null Citalopram (hydrobromide)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0262717 intracellular part GO Cellular Component Annotations 2015 1.0 null GTEX-XOTO-0011-R7B-SM-4B64R GTEx Tissue Sample Gene Expression Profiles 1.0 1.13292 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.85829 COR-L303 COSMIC Cell Line Gene Mutation Profiles 1.0 null cadherincatenin GeneRIF Biological Term Annotations 1.0 null Hypertension HuGE Navigator Gene-Phenotype Associations 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.835317 SkeletalMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.87986 GSE174701_5_v_3_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Microtubule organizing center COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR Rummagene Transcription Factor Associations 2026 1.0 null disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 SUM185PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.760939 GSE184133,GSE184137_2_v_5_esrrb_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11891 H3255 COSMIC Cell Line Gene Mutation Profiles 1.0 null K562_Danusertib_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.020861 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.256561 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00938 nuclear part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PMC11542230-12985_2024_2548_MOESM4_ESM.xlsx-MR_results-exposure_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE119978,GSE180930_0_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null tonsil HPA Tissue Protein Expression Profiles 1.0 1.10642 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.75107 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IG-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intracellular vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68922 Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECC10 COSMIC Cell Line Gene Mutation Profiles 1.0 null PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.89371 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-338-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00392 hsa-miR-4276 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 K562_Hesperadin_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0197936 abnormality of central motor function GWASdb SNP-Phenotype Associations 1.0 0.704609 associations GeneRIF Biological Term Annotations 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null hsa-miR-548d-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 abnormal total tissue mass MPO Gene-Phenotype Associations 1.0 null GSE147056_4_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null TT COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11439 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065657 breast HPA Tissue Protein Expression Profiles -1.0 -0.865861 hsa-miR-1256 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.7532 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02912 ZC3H11C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18567 ZNF207 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02657 periventricular stratum of cerebellar vermis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15743 decreased body size MPO Gene-Phenotype Associations 1.0 null GTEX-OIZI-0426-SM-2XCEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.945319 PMC3919509-NIHMS471461-supplement-3.xls-Table_S1-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null synaptic Phosphosite Textmining Biological Term Annotations 1.0 null Dystonia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.375 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-465-ENSG00000162599_NFIA Rummagene Transcription Factor Associations 2026 1.0 null Copula pyramidis, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39927 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.05347 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 1.33168 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11393 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE201520_8_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null XRN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58523 GTEX-N7MT-0126-SM-2D7VT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.882063 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-2682 TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 plasma membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.002119 GSE205163,GSE205164_3_v_7_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.052787 primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.04239 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833991 icSARS-Cov_Day1_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.82742 PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_14148_KO_KBTBD4_SRP279638 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.40641 GSE214514_1_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.853 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.54113 intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-T6MO-0526-SM-4DM6R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67646 ZNF318 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13057 hsa-miR-4704-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA ChEA Transcription Factor Targets 2022 1.0 null Perturb_17625_KO_TP53_SRP153109 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.81295 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09553 hsa-miR-559 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Hypertension DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.884497 NR3C1 ChEA Transcription Factor Targets 1.0 null NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.1586 Cell periphery COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.551 Cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 1.26084 INA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03902 ONS76 CCLE Cell Line Gene CNV Profiles -1.0 -1.39321 attention deficit disorder with hyperactivity GAD Gene-Disease Associations 1.0 null MELK_knockdown_150_GSE32873 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.31801 CCNQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37372 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 2.59908 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.31423 TAL1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null RAF/MAP kinase cascade Reactome Pathways 2024 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.40909 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36779 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.10417 Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tenia tecta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.704 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESRRB-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03703 GSE131649_6_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE150669_2_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures -1.0 null HDMYZ CCLE Cell Line Gene Expression Profiles -1.0 -2.0884 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20119 HCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928808 SNU719 DepMap CRISPR Gene Dependency 1.0 3.52561 rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13605 GSE229973_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null GSE213588_10_v_11_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75642 Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GRANTA519 CCLE Cell Line Gene CNV Profiles -1.0 -1.7399 Myf MotifMap Predicted Transcription Factor Targets 1.0 null ECC2 DepMap CRISPR Gene Dependency 1.0 3.36212 PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_17362_Mut|OE_Sik3E13_SRP334442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE195568_2_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.73338 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.30413 GSE201042_2_v_1_ptpmt1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0633 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE153836_14_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.753297 GSE97278,GSE97280_2_v_1_nsd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09034 syntrophin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.561772 GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.11247 GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.52956 physical disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053638 abnormal locomotor activation MGI Mouse Phenotype Associations 2023 1.0 null GSE190681_1_v_0_rtcb_mouse RummaGEO Gene Perturbation Signatures 1.0 null centrosome COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 1.71 Cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.49594 GTEX-TSE9-0011-R7A-SM-3DB7P GTEx Tissue Sample Gene Expression Profiles 1.0 0.874383 Proteinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05309 GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.824463 GSE150072,GSE169209_6_v_11_qser1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE153757,GSE153758_1_v_3_ftsj1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Mozavaptan_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0280192 Post NMDA receptor activation events Reactome Pathways 2024 1.0 null GSE253041_3_v_0_ramp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMRC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.48812 cytoplasm GO Cellular Component Annotations 2015 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56002 hsa-miR-124 TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.204263 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16537 GSE186647,GSE217287_1_v_3_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954315 H2AFZ ENCODE Transcription Factor Targets 1.0 null Artesunate_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0215482 RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WVLH-0011-R4A-SM-3MJFS GTEx Tissue Sample Gene Expression Profiles 1.0 1.05319 GSE102269_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95877 increased aggression towards mice MPO Gene-Phenotype Associations 1.0 null TAK-901_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.00592786 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837182 GSE164874_5_v_10_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.281085 BOSC-23 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.168 short attention span GWASdb SNP-Phenotype Associations 1.0 0.942765 abnormal emotion/affect behavior MPO Gene-Phenotype Associations 1.0 null abnormal voluntary movement MPO Gene-Phenotype Associations 1.0 null Central lateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06112 bronchus HPA Tissue Protein Expression Profiles 1.0 1.77778 Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell junction COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.417 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126127_5_v_3_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.51331 JHUEM7 CCLE Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A266-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.52448 GSE89018_10_v_2_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.08998 BRCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44454 Prostate adenocarcinoma_PRAD_TCGA-EJ-5519-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUZC-1126-SM-4BOPZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14437 GSE121824,GSE121826_0_v_3_scaf8_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 associating GeneRIF Biological Term Annotations 1.0 null HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87544 alk GeneRIF Biological Term Annotations 1.0 null GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11019 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27865 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14809 HCC1806 DepMap CRISPR Gene Dependency 1.0 2.09518 organelle inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.123964 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.52503 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.511384 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.918759 GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 1.41852 GTEX-X4XY-0326-SM-46MVZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05187 hsa-miR-218 TargetScan Predicted Conserved microRNA Targets 1.0 0.107229 Scoliosis, Isolated, Susceptibility To, 3 DisGeNET Gene-Disease Associations 1.0 null Perturb_7463_KD_RBM17_SRP126064 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -19.5229 GSE84148,GSE96938_0_v_2_nrros_mouse RummaGEO Gene Perturbation Signatures 1.0 null against GeneRIF Biological Term Annotations 1.0 null GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12561 depression GWASdb SNP-Phenotype Associations 1.0 0.402102 membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE229973_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43091 Caudoputamen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08608 SALL4-28974232-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null RCM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67317 GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100537_FWM_no dementia_TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.04471 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46088 decreased prepulse inhibition MGI Mouse Phenotype Associations 2023 1.0 null GSE245270_1_v_4_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null Endoplasmic reticulum tubular network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.806 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null rt4 HPA Cell Line Gene Expression Profiles -1.0 -1.68688 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.56018 KM12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_12547_KO_Shank2_SRP309197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.74374 DDX41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4417 hsa-miR-424 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982851 GSE205070_2_v_9_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null KMS27 CCLE Cell Line Gene Mutation Profiles 1.0 null hypertension GWASdb SNP-Phenotype Associations 1.0 1.19958 GSE120595_5_v_4_arid2_mouse RummaGEO Gene Perturbation Signatures -1.0 null abnormal sensory capabilities/reflexes/nociception MPO Gene-Phenotype Associations 1.0 null CORL279 CCLE Cell Line Gene Expression Profiles 1.0 1.38062 GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15553 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.585 ventral subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45434 Slit diaphragm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.013 nod2_21335489_hek293_lof_human_gpl570_gds4416 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.443104 GNL3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60619 behavior/neurological phenotype MPO Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4827-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_7_v_5_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905384 GSE142684_2_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29999 GSE171837_3_v_2_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null Hepatitis C virus genotype 1b (isolate Con1) Virus MINT Protein-Virus Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bestatin (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0136174 Huntington's Disease_Lymphocyte_GSE8762 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.96182 K562_TAK-901_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0139603 GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.59983 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03995 GSE198165,GSE198166_9_v_1_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4659b-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.219115 GATA1-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07992 NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null neurotransmitter receptor transport, endosome to postsynaptic membrane GO Biological Process Annotations 2023 1.0 null PFDN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40895 type GeneRIF Biological Term Annotations 1.0 null primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983038 TP53-18474530-U2OS-human ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4762-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 increased aggression MPO Gene-Phenotype Associations 1.0 null GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71732 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2993 hsa-miR-4517 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 BB65-RCC Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.83113 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47294 hsa-miR-548i TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE210580_5_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-656 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 autophosphorylation Phosphosite Textmining Biological Term Annotations 1.0 null r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10442 ACTN2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2797 EN CCLE Cell Line Gene Mutation Profiles 1.0 null primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.994508 nuclear membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.13473 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.940275 Cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 densin180 GeneRIF Biological Term Annotations 1.0 null GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uvula (IX), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25747 PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57516 Long-term potentiation Reactome Pathways 2024 1.0 null 16207381-Table1Sa GeneSigDB Published Gene Signatures 1.0 null calcium Phosphosite Textmining Biological Term Annotations 1.0 null cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.236324 Q9WMX2 Virus MINT Protein-Viral Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.90469 hsa-miR-4653-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 autoantigen GeneRIF Biological Term Annotations 1.0 null posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.828683 abnormal synaptic transmission MPO Gene-Phenotype Associations 1.0 null GTEX-U3ZH-1626-SM-3DB74 GTEx Tissue Sample Gene Expression Profiles 1.0 0.874806 GSE147056_3_v_1_actl6b_mouse RummaGEO Gene Perturbation Signatures -1.0 null CCLFPEDS0003T DepMap CRISPR Gene Dependency 1.0 2.14476 GSE147876,GSE147877_4_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null HCT8 CCLE Cell Line Gene Expression Profiles -1.0 -2.01611 GSE210911_1_v_0_crem_human RummaGEO Gene Perturbation Signatures -1.0 null GCT COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.73999 GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.42098 Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.5411 Perturb_3908_KD_ALDH1A1_SRP164778 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.26136 NCI-H1944 COSMIC Cell Line Gene Mutation Profiles 1.0 null chr1_69542695_C_T_b38 GTEx eQTL 2025 1.0 6.54608 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3834 GSE119978,GSE180930_0_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4530 TargetScan Predicted Conserved microRNA Targets 1.0 0.32519 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17547 cell part LOCATE Predicted Protein Localization Annotations 1.0 null PLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21466 Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RKO CCLE Cell Line Gene Mutation Profiles 1.0 null ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.085 intermediate stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07795 hsa-miR-548l TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RSL1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43208 GSE125219,GSE125221_3_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829464 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8227 Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE119978,GSE180930_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null CAMK2A Pathway Commons Protein-Protein Interactions 1.0 null diabetic GeneRIF Biological Term Annotations 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles 1.0 2.04155 CORL279 CCLE Cell Line Gene Mutation Profiles 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.50576 GSE174701_1_v_6_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00819 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21122 DU-145 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.56468 GSE195713_0_v_1_lapatinib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles 1.0 1.12241 GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.51194 GSE201239_0_v_7_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Perturb_3610_KO_BCL7B_SRP127343 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.50407 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.521888 specific developmental disorder GWASdb SNP-Disease Associations 1.0 0.194827 Garland cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.594 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.74602 GSE153836_11_v_2_fluoxetine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Neuron to neuron synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.497 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.9361 Vesicle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.846796 SKRC20 DepMap CRISPR Gene Dependency 1.0 3.13646 Centrosome COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.484 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.90321 Hepm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.501 submedius thalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40629 Medial geniculate complex, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44816 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93089 GTEX-SN8G-0926-SM-4DM5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.997583 NSUN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03144 CMK CCLE Cell Line Gene Expression Profiles 1.0 1.64165 GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.11483 PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE245270_2_v_5_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null RCHACV_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 5.05308 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40806 limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.773174 hsa-miR-513a-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.274552 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69155 cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08686 Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52984 TGBC24TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null Cetirizine DeepCoverMOA Drug Mechanisms of Action 1.0 0.31 intracellular organelle part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Pierson syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 C2BBE1 CCLE Cell Line Gene CNV Profiles -1.0 -1.48932 hsa-miR-3929 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 NCI-H23 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null NCIH441 CCLE Cell Line Gene Mutation Profiles 1.0 null CAOV3 CCLE Cell Line Gene Expression Profiles -1.0 -1.48744 TUBGCP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17338 Perturb_16629_KO_Kir4.1_SRP133512 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.91838 GTEX-XPT6-0008-SM-4B64Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1028 OVCA 420 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943734 hsa-miR-3159 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 K562_Dasatinib_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0203102 HCC4006 CCLE Cell Line Gene Mutation Profiles 1.0 null Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20587 PDZ domain InterPro Predicted Protein Domain Annotations 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Chlorsulfuron DeepCoverMOA Drug Mechanisms of Action 1.0 0.35 ASPC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SW962 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SHF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21033 GTEX-QVJO-1426-SM-2S1QY GTEx Tissue Sample Gene Expression Profiles 1.0 0.876151 RBM39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52455 cerebellar cortex_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.28496 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36543 VCPKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07615 Endoplasmic reticulum cisternal network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.519 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147876,GSE147877_4_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null hTERT-RPE1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.743 Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548w TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 hsa-miR-4534 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 Fatty Liver Disease DisGeNET Gene-Disease Associations 1.0 null STAT1 ChEA Transcription Factor Targets 1.0 null GSE128333_2_v_5_tcf4_human RummaGEO Gene Perturbation Signatures 1.0 null VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08735 PECAPJ34CLONEC12_UPPER_AERODIGESTIVE_TRACT CCLE Cell Line Proteomics 1.0 3.6072 synaptic GeneRIF Biological Term Annotations 1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Attention deficit hyperactivity disorder GWAS Catalog SNP-Phenotype Associations 1.0 0.104568 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.0325 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22928 UPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73268 Tirabrutinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0285217 PMC4495416-srep12003-s1.pdf-23-ZNF385A_ZNF385A Rummagene Transcription Factor Associations 2026 1.0 null adherens junction GO Cellular Component Annotations 2023 1.0 null SNU1040 CCLE Cell Line Gene Mutation Profiles 1.0 null Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 61.8828 COLO824 DepMap CRISPR Gene Dependency 1.0 7.12287 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30733 PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8121 Non-Alcoholic Fatty Liver Disease DisGeNET Gene-Disease Associations 1.0 null Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62653 Gemcitabine_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0239768 common GeneRIF Biological Term Annotations 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837765 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.133987 PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U4B1-0626-SM-3DB8L GTEx Tissue Sample Gene Expression Profiles 1.0 0.896802 abnormal parental behavior MPO Gene-Phenotype Associations 1.0 null GTEX-S4Q7-0426-SM-3K2BJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02889 YD15 CCLE Cell Line Gene Mutation Profiles 1.0 null NUBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79997 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Basal ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE122101,GSE122103_0_v_4_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43623 TAGLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50068 GSE129241_4_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-TKQ1-1126-SM-4GIAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01156 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869396 ULK-101_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0132234 Discoidal high-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.515 PSMD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57071 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.137973 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAFA-gene_MAFA Rummagene Transcription Factor Associations 2026 1.0 null Medial geniculate complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27024 neuron spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.234 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null BI-3406_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.021868 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SE5C-0426-SM-4BRUI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924202 interacting GeneRIF Biological Term Annotations 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.88656 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8766 GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917923 sertoli GeneRIF Biological Term Annotations 1.0 null GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.36025 COV318 CCLE Cell Line Gene CNV Profiles 1.0 1.43369 GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60271 GSE149096_4_v_0_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null Mood disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 nuclear inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.28846 Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein localization to early endosome GO Biological Process Annotations 2023 1.0 null GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14256 ChIP_RNF2_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.29872 Glomerular endothelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.83 hsa-miR-1264 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.05117 Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548h TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.825473 GTEX-T5JC-0011-R4A-SM-32PLT GTEx Tissue Sample Gene Expression Profiles 1.0 0.874696 GSE92457_7_v_8_ethanol_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868811 GSE157555,GSE157556_5_v_1_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE195568_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null HNRNPA1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26394 susceptibility GeneRIF Biological Term Annotations 1.0 null Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKLU1_LUNG CCLE Cell Line Proteomics 1.0 2.62802 GSE118766_2_v_3_ifng_mouse RummaGEO Gene Perturbation Signatures 1.0 null AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H2029 COSMIC Cell Line Gene Mutation Profiles 1.0 null Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07943 STAV-AB cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.442 GSE117212,GSE117214_2_v_1_zbtb1_human RummaGEO Gene Perturbation Signatures 1.0 null ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12441 SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.68385 Perturb_14527_KO_Foxa2/Gata4/Nr5a2/Ptf1a_SRP111204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.884197 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4866-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_4_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null capsular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289582 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 2.51782 mdck cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.305361 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDK1 Hub Proteins Protein-Protein Interactions 1.0 null GSE245270_1_v_5_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null Geniculate group, dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04905 ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.05346 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17567 Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LU-135 COSMIC Cell Line Gene Mutation Profiles 1.0 null mcf7 HPA Cell Line Gene Expression Profiles -1.0 -1.68688 PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_S21T_vs_wt-Gene_Symbol_THAP1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.853424 GSE123372,GSE123373_10_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Secretory granule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GSE195559_2_v_7_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF148 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17557 Sleep HuGE Navigator Gene-Phenotype Associations 1.0 null Depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.12056 dendrites Phosphosite Textmining Biological Term Annotations 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GBX1_GBX1 Rummagene Transcription Factor Associations 2026 1.0 null SKNBE2 CCLE Cell Line Gene Expression Profiles 1.0 1.4601 PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4528 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 K562_INO-1001_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0162405 Cobimetinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0604735 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.598 BL1737 (CARM1) NURSA Protein Complexes 1.0 null GSE101112_0_v_4_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23694 JARID2-20064375-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-WYVS-2426-SM-3NMA9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0492 GSE164874_5_v_6_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null Transmission across Chemical Synapses Reactome Pathways 2024 1.0 null Salicylic acid_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0159379 GTEX-WYJK-0005-SM-3NMA1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2769 PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11633 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34973 decreased body size MGI Mouse Phenotype Associations 2023 1.0 null postsynaptic membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-XMD1-0011-R10A-SM-4AT4A GTEx Tissue Sample Gene Expression Profiles 1.0 0.823998 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.978493 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE118766_1_v_0_ifng_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE230354_0_v_1_rheb_mouse RummaGEO Gene Perturbation Signatures 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.518072 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null Dendritic branch COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.162 NCI-H1963 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980693 LOU-NH91 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.22484 GTEX-OOBK-0226-SM-2YUMF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44554 Cri-Du-Chat syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.955 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.953639 brain_3c HPA Tissue Sample Gene Expression Profiles 1.0 1.93991 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JC-0011-R1A-SM-32PM6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31829 cell periphery COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Medial group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19649 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.865861 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_5347_OE_Gli3T_SRP272033 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.45052 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38302 GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.07984 GSE245270_2_v_4_isoproterenol_human RummaGEO Drug Perturbation Signatures 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00572 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.08788 KNS-81-FD COSMIC Cell Line Gene Mutation Profiles 1.0 null VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937521 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.403637 A3-KAW COSMIC Cell Line Gene Mutation Profiles 1.0 null icSARS-Cov_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.23212 GTEX-W5X1-2826-SM-3GILM GTEx Tissue Sample Gene Expression Profiles 1.0 0.839372 organization GeneRIF Biological Term Annotations 1.0 null Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51592 NCI-H2126 COSMIC Cell Line Gene Mutation Profiles 1.0 null Norepinephrine (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0245015 NCIH1105 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64715 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.985665 GTEX-Q2AG-0011-R6A-SM-2HML7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63005 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.63215 hsa-miR-381 TargetScan Predicted Conserved microRNA Targets 1.0 0.119151 PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Conserved_gene_regulation_during_acute_inflammation_between_zebrafish_and_mammals_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.19746 oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25479 SBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40806 mood disorder GWASdb SNP-Disease Associations 1.0 0.360923 SUZ12-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null chr1_69498192_A_T_b38 GTEx eQTL 2025 1.0 2.74725 GTEX-QDT8-2926-SM-32PKC GTEx Tissue Sample Gene Expression Profiles 1.0 1.16828 DLG4 Pathway Commons Protein-Protein Interactions 1.0 null VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.99359 disease by infectious agent GWASdb SNP-Disease Associations 1.0 0.149436 8305C COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glutamatergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.898 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.968357 Attention Deficit Disorder with Hyperactivity dbGAP Gene-Trait Associations 1.0 0.378873 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.54991 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32531 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.99563 forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.85546 MOLM16 CCLE Cell Line Gene Expression Profiles 1.0 1.5692 H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.84334 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44927 hsa-miR-4722-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 HCC1187 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.66878 Familial adult myoclonic epilepsy 5 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.223 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null Breast leiomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.312 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.268 bacterial infectious disease GWASdb SNP-Disease Associations 1.0 0.29872 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.99899 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12548 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null associate GeneRIF Biological Term Annotations 1.0 null hsa-miR-4274 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 KYSE140 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE239373_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Flumatinib (mesylate)_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0317165 GSE229973_3_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Copula pyramidis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39374 SH4 CCLE Cell Line Gene Expression Profiles -1.0 -1.45485 Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CL-34 COSMIC Cell Line Gene Mutation Profiles 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040675 E2F4_02_200 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62015 MIS18BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01543 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4836-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07233 PMC11625982-AJH-100-10-s001.pdf-91-ZNF841_ZNF841 Rummagene Transcription Factor Associations 2026 1.0 null Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28526 Body Height dbGAP Gene-Trait Associations 1.0 0.593839 HCC827 CCLE Cell Line Gene CNV Profiles 1.0 1.38495 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.55013 Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.875 hsa-miR-4251 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PMC5722633__F4 PFOCR Pathway Figure Associations 2023 1.0 null cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.66226 Basal part of cell COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.324 superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00545 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.952944 SDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65685 TE1_OESOPHAGUS CCLE Cell Line Proteomics 1.0 2.14038 CDCP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10537 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null Osmiophilic body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 finnish GeneRIF Biological Term Annotations 1.0 null GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.10165 Capmatinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0321865 Spleen GTEx Tissue Gene Expression Profiles 2023 1.0 1.75283 GSE157555,GSE157556_3_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34392 GSE147876,GSE147877_2_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.793078 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.929219 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 0.752335 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PHB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62418 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65625 MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.29958 central part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40629 GSE153836_14_v_5_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null CSNK2A1 KEA Substrates of Kinases 1.0 null OVCAR-8 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.31918 WDR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24509 DTP3_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0253874 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.04831 QGP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Plasma membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.973283 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054758 epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461465 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.04194 GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.36573 Microtubule organizing center COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.484 PMC4042849-rsob-4-140029.pdf-4-P53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null MZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08582 UACC62 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles 1.0 1.16741 GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 1.06904 HT29 CCLE Cell Line Gene Mutation Profiles 1.0 null endometrium_4a HPA Tissue Sample Gene Expression Profiles -1.0 -0.892224 GSE120612_7_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55E-0011-R8A-SM-2TC66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835836 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.07159 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01825 MHH-PREB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2286 CCLE Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68866 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33222 HS840T CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UDSCC2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE218060_2_v_4_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null K562_AMG-900_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0200749 SBK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40452 CMK115 CCLE Cell Line Gene Expression Profiles 1.0 1.55944 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-AAQO-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null increased aggression towards mice MGI Mouse Phenotype Associations 2023 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Filopodium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.224 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.52555 HCC1395 CCLE Cell Line Gene CNV Profiles -1.0 -2.34759 PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null NCIH650 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 1.16751 rpmi8226 HPA Cell Line Gene Expression Profiles 1.0 0.965916 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.58961 GSE180800,GSE180801_0_v_5_tex10_mouse RummaGEO Gene Perturbation Signatures 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.4831 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.7571 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15396 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35622 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30576 Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4241 Type IB spiral ganglion neuron_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.694 DMS-53 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 Tadalafil_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0297815 PLEKHA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06061 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68633 c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.855974 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49321 GSE102757_1_v_0_panobinostat_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE226544_1_v_0_hnrnpa2b1_human RummaGEO Gene Perturbation Signatures 1.0 null Neuronal System Reactome Pathways 2024 1.0 null TSC22D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32074 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.464771 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19131 filtration diaphragm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.199993 GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC7021003-NIHMS1547395-supplement-5.xlsx-Gene_Signatures_Fig_3_5_ED8-SOX9_TARGET_GENES_SOX9 Rummagene Transcription Factor Associations 2026 1.0 null SNU175 CCLE Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4497 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SW780 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.91836 GSE162892_3_v_1_isox_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.68383 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36891 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.869747 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79953 postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.07714 GTEX-T8EM-1526-SM-3DB7I GTEx Tissue Sample Gene Expression Profiles 1.0 0.859298 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-2115 TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 K562_Trametinib_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.015906 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10498 PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC5722633__F4 PFOCR Pathway Figure Associations 2024 1.0 null GTEX-R55E-0011-R7A-SM-2TC5Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.16417 HCV_8week+IFN-a_None_GSE37715 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.66932 GSE205070_2_v_7_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE133505_5_v_4_myf6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE229973_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null brainspecific GeneRIF Biological Term Annotations 1.0 null (S)-(-)-Pindolol DeepCoverMOA Drug Mechanisms of Action 1.0 0.27 GSE139325_0_v_3_cd36_mouse RummaGEO Gene Perturbation Signatures 1.0 null ALG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10809 chr1_69723599_T_C_b38 GTEx eQTL 2025 1.0 2.71749 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 0.882876 GTEX-XOT4-0326-SM-4B66S GTEx Tissue Sample Gene Expression Profiles 1.0 0.953071 Perturb_9047_OE_PRRX1A_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -10.5343 GSE150072,GSE169209_4_v_11_qser1_human RummaGEO Gene Perturbation Signatures 1.0 null NCC021 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.94348 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112714_2_v_0_ctnnb1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JC-0011-R7A-SM-32PME GTEx Tissue Sample Gene Expression Profiles 1.0 1.42597 ALL-SIL COSMIC Cell Line Gene Mutation Profiles 1.0 null Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.9958 GSE219274,GSE219276_2_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13422 SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.30951 ESRRB ChEA Transcription Factor Targets 1.0 null GATA1-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-1726-SM-2S1R7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.973178 Dendritic shaft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.56 unlike GeneRIF Biological Term Annotations 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22835 GSE113329,GSE113335_2_v_4_taf6l_mouse RummaGEO Gene Perturbation Signatures 1.0 null diabetes GeneRIF Biological Term Annotations 1.0 null mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13078 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.96106 LU99 CCLE Cell Line Gene CNV Profiles 1.0 2.47577 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -0.865861 fat_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.05947 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4959-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null camkii Phosphosite Textmining Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-1594-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neurotransmitter receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.556 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196339 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31071 superficial stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66588 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39903 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial geniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66588 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.31314 specific granule lumen GO Cellular Component Annotations 2023 1.0 null striatum_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865848 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.43187 STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE210101,GSE210114_2_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Mesenchymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.691 ca2calmodulindependent GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cisplatin_homo sapiens_gpl6480_gse33482 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.02208 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59646 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.39758 GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 0.85919 GSE118816_0_v_1_myo1c_human RummaGEO Gene Perturbation Signatures 1.0 null urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043794 Lactate (calcium)_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0339996 HEC59 CCLE Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1606 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16912 Lung adenocarcinoma_LUAD_TCGA-MP-A4SV-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 4EGI-1_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0115433 GTEX-N7MT-1426-SM-3LK5M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.964258 Synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.307 BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.68482 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.067693 Perturb_12098_KO_Brca1_SRP256316 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.83301 ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1825 NR1D2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0714 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.219 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HT COSMIC Cell Line Gene Mutation Profiles 1.0 null CGTH-W-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null consists GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (ventral) nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18711 primary bacterial infectious disease GWASdb SNP-Disease Associations 1.0 0.389827 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.97674 NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40048 EZH2-18974828-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null centromedian nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28526 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.840709 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06281 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.9122 VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.888755 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.884497 posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.57263 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53303 Mathematical Ability DisGeNET Gene-Phenotype Associations 1.0 null GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 2.09136 XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus) WikiPathways Pathways 2014 1.0 null PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GSE42805,GSE42811_2_v_3_cocaine_mouse RummaGEO Drug Perturbation Signatures 1.0 null CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3271 GTEX-PWOO-0826-SM-48TCL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42436 RPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16936 regulation of neuron projection development GO Biological Process Annotations 2023 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.983038 parkinsonism GWASdb SNP-Phenotype Associations 1.0 0.704609 PMC6815046-13073_2019_678_MOESM3_ESM.xlsx-MYT1L-Unnamed_0_MYT1L Rummagene Transcription Factor Associations 2026 1.0 null integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.137972 RSL24D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11946 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06989 20018718-TableS2 GeneSigDB Published Gene Signatures 1.0 null Apical junction complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.341 Belumosudil_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0282175 selectively GeneRIF Biological Term Annotations 1.0 null lrrc7 GeneRIF Biological Term Annotations 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.253291 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901979 hsa-miR-3910 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 GSE100217_2_v_3_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54615 lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54784 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837182 KP-3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.58501 E2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.1142 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970901 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 obesity GWASdb SNP-Phenotype Associations 1.0 0.899912 Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41701 GSE60691_2_v_1_glutamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.2966 PLEKHO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30909 RH30 CCLE Cell Line Gene CNV Profiles 1.0 1.65014 POLR2A ENCODE Transcription Factor Targets 1.0 null GTEX-PVOW-0626-SM-2XCF6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29298 PMC10684515-41467_2023_43264_MOESM7_ESM.xlsx-HOXA9_ChIP-seq_peaks_in_SEM-Closest_Gene_HOXA9 Rummagene Transcription Factor Associations 2026 1.0 null GSE205163,GSE205164_2_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null TIMM17B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88712 GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OX-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.11321 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436 Rummagene Transcription Factor Associations 2026 1.0 null ALLSIL CCLE Cell Line Gene Mutation Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38085 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.862021 positive regulation of cell projection organization GO Biological Process Annotations 2023 1.0 null GTEX-N7MT-0011-R4a-SM-2I3G9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88101 GSE228894_0_v_1_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETC-206_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0157734 Ophthalmic nerve TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 SW954 DepMap CRISPR Gene Dependency 1.0 2.06438 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47819 putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969512 NCI-H2722 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 3.5185 K562_Nilotinib_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0180409 Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 GSE145311_1_v_2_glutathione_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63774 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.356 PIK3R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86333 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SNU81 CCLE Cell Line Gene Mutation Profiles 1.0 null COLO-800 COSMIC Cell Line Gene Mutation Profiles 1.0 null CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.9151 GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.461 Lateral group of the dorsal thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2496 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954315 SCC9 DepMap CRISPR Gene Dependency 1.0 3.79083 HCC1438 CCLE Cell Line Gene Mutation Profiles 1.0 null Galloway-Mowat syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.139 GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles 1.0 1.247 Triclosan_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0228434 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.01122 Pirenzepine DeepCoverMOA Drug Mechanisms of Action 1.0 0.74 GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 0.911144 GSE192860_0_v_1_trifluoperazine_human RummaGEO Drug Perturbation Signatures -1.0 null ChIP_MTF2_20144788 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-4478 TargetScan Predicted Conserved microRNA Targets 1.0 0.389112 TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11486 PMC6815046-13073_2019_678_MOESM2_ESM.xlsx-MYT1L-Unnamed_0_MYT1L Rummagene Transcription Factor Associations 2026 1.0 null HEL9217 CCLE Cell Line Gene CNV Profiles 1.0 1.55745 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929094 putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.961657 GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.746381 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20714 STAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27715 NCI-H1755 COSMIC Cell Line Gene Mutation Profiles 1.0 null chr1_69712271_C_T_b38 GTEx eQTL 2025 1.0 1.01539 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.59688 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10805 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02512 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14224 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.077895 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.124517 TRAPPC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08864 CCLFUPGI0005T DepMap CRISPR Gene Dependency 1.0 2.83523 central lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05304 abnormal response to novelty MPO Gene-Phenotype Associations 1.0 null NCI-H1437 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.14987 5-Fluorouracil_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0334183 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17808 ATP6V1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3296 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16537 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55905 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16537 X-Linked Emery-Dreifuss Muscular Dystrophy DisGeNET Gene-Disease Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XRK3F2_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0315469 EX229_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0219282 urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071336 cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 periventricular stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04108 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824673 FGFR3_knockdown_34_GDS4454 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.48935 HSFX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09507 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14349_KD_CDK12_SRP223931 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.955526 CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R55C-1626-SM-48FEG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07915 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.44802 HCC1395_BREAST CCLE Cell Line Proteomics 1.0 2.07853 cell-substrate junction COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.417 GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 1.1716 HNF3A MotifMap Predicted Transcription Factor Targets 1.0 null cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.289938 lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12213 Basal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.62 NB17 COSMIC Cell Line Gene Mutation Profiles 1.0 null focal adhesion COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 KYSE-140 COSMIC Cell Line Gene Mutation Profiles 1.0 null NEURL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42631 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0052 NR2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61811 GSE164874_5_v_9_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 DDX39B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08636 hsa-miR-4470 TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.212 Cortical endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.819 Adventurousness GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.75243 abnormal anxiety-related response MPO Gene-Phenotype Associations 1.0 null primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01666 synaptic membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Unblocking of NMDA receptors, glutamate binding and activation Reactome Pathways 2024 1.0 null SNU738 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE210580_0_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 hsa-miR-548a-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 DLG4 Hub Proteins Protein-Protein Interactions 1.0 null central GeneRIF Biological Term Annotations 1.0 null GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.41942 GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 1.20318 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.079 NYNRIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4364 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-491-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.898 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11457 HCC33 CCLE Cell Line Gene Expression Profiles 1.0 1.94279 c-Rel MotifMap Predicted Transcription Factor Targets 1.0 null VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.872286 MFAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41831 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25127 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35205 BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64715 Skin BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.16393 GTEX-TMZS-0226-SM-3DB9N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869732 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP Rummagene Transcription Factor Associations 2026 1.0 null temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.863891 GSE145990_1_v_0_ibrutinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBM42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43046 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null GSE174701_1_v_2_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null OCIM1 CCLE Cell Line Gene Expression Profiles 1.0 2.07784 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44252 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970901 HUO9 COSMIC Cell Line Gene Mutation Profiles 1.0 null Ribbon synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.861 TE6 CCLE Cell Line Gene Expression Profiles 1.0 1.79973 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.34321 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MAFK ENCODE Transcription Factor Targets 1.0 null PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carbidopa (monohydrate)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0203599 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRDM16 ChEA Transcription Factor Targets 1.0 null PC3 DepMap CRISPR Gene Dependency 1.0 3.01627 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96343 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 COLO680N DepMap CRISPR Gene Dependency 1.0 2.15196 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09196 GTEX-U8XE-0826-SM-4E3J1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51334 SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.78067 CP21R7_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0250392 Perturb_8766_KD_H19_SRP073245 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.45469 OXA1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32198 PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF Rummagene Transcription Factor Associations 2026 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.516497 cerebellar vermis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27815 cellular_component GO Cellular Component Annotations 2015 1.0 null cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.08722 Diabetes Mellitus, Type 1 HuGE Navigator Gene-Phenotype Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A204_SOFT_TISSUE CCLE Cell Line Proteomics 1.0 2.63802 abnormal short term spatial reference memory MPO Gene-Phenotype Associations 1.0 null PMC7412812-13059_2020_2115_MOESM9_ESM.xlsx-Negative_correlation-Also_present_in_upregulated_set_in_SERBP1_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.68004 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null HIVEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61595 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Microtubule cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 CJUN-26792858-CHIP-SEQ-BT549-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE195568_2_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null secretory granule lumen GO Cellular Component Annotations 2025 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inhibitory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.328 RXF393 COSMIC Cell Line Gene Mutation Profiles 1.0 null FTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49723 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67795 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.853 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.664232 ZWILCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61297 GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ovary HPA Tissue Protein Expression Profiles -1.0 -0.865861 GIMEN DepMap CRISPR Gene Dependency 1.0 2.69674 r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46808 COR-L279 COSMIC Cell Line Gene Mutation Profiles 1.0 null TDOTT DepMap CRISPR Gene Dependency 1.0 2.18297 PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3 Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.96502 PMC12443547-DataSheet5.pdf-3-WT1_WT1 Rummagene Transcription Factor Associations 2026 1.0 null membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_3645_KO_EP300_ERP115567 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.81341 postsynaptic membrane GO Cellular Component Annotations 2015 1.0 null located GeneRIF Biological Term Annotations 1.0 null ZNF574 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.6227 GSE174498,GSE174500_0_v_8_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.61463 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.064684 pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.07472 SUP-HD1 COSMIC Cell Line Gene Mutation Profiles 1.0 null integral component of postsynaptic density membrane SynGO Synaptic Gene Annotations 1.0 null posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05715 GTF2H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65637 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null HEC1B CCLE Cell Line Gene Mutation Profiles 1.0 null LB831-BLC Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.38638 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.40078 artery disease GWASdb SNP-Disease Associations 1.0 0.180996 Trigeminal nerve TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 tsA-201 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.968 MRK-NU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.968219 Hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.01 cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.903204 Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2227 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -1.74506 synapse part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PCI-4B Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.02017 Perisynaptic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.552 GSE157555,GSE157556_4_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null cellcell GeneRIF Biological Term Annotations 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 hsa-miR-3913-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-P44H-0011-R8A-SM-2XCEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.03314 Dentate granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.762 primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.09139 GTEX-R55E-0011-R6A-SM-2TC5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.47778 Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE224969,GSE224971_0_v_7_chtop_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles 1.0 0.824034 GSE232624_4_v_5_ethanol_human RummaGEO Drug Perturbation Signatures -1.0 null Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85919 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.190185 hsa-miR-4495 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-T5JW-1726-SM-3GADN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98497 SUDHL6 CCLE Cell Line Gene Mutation Profiles 1.0 null Human - Fetal Development - L2 - Cerebrum-Inhibitory neurons HuBMAP Azimuth Cell Type Annotations 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE213715_0_v_1_iqgap2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.89743 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Apical recycling endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.568 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28939 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52529 PMC6420620-41598_2019_Article_39571.nxml--Receptome_CPC_vs_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21747 GTEX-NPJ7-0011-R1a-SM-3GACT GTEx Tissue Sample Gene Expression Profiles 1.0 1.21309 GSE195513_2_v_1_cpeb1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.86025 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3269 GATA2 ChEA Transcription Factor Targets 1.0 null SW1271 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.81583 BV173 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE239541_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.890795 FADU COSMIC Cell Line Gene Mutation Profiles 1.0 null EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null BRAF_drug inhibition_GSE42872_368_human_A375 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Primary dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.896 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 1.14429 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.82596 GTEX-T6MN-2626-SM-32PMQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.998998 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles 1.0 1.30235 PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null DOTC2-4510 COSMIC Cell Line Gene Mutation Profiles 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17193 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01507 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.93139 Homocarnosinosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.415 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.85997 Perturb_15232_OE_Zscan4f_SRP229595 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.06475 abnormal synaptic depression MPO Gene-Phenotype Associations 1.0 null Fragile X syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 Allopurinol_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0278324 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.867616 organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Nuclear membrane protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.068 intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.379276 Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE219103,GSE219104_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null AMPA glutamate receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.46 MZ in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46749 NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86999 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55047 hsa-miR-4477b TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 HEC108 CCLE Cell Line Gene Mutation Profiles 1.0 null hsa-miR-133b TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17716 hsa-miR-449a TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.878982 SW780 CCLE Cell Line Gene Mutation Profiles 1.0 null ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.850137 PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Inner hair cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.132 mantle zone of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06536 intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 palbociclib_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0282621 ATL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.96677 protein binding GO Molecular Function Annotations 2015 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.289938 GSE206516,GSE206518_1_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.361 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 tmem132d GeneRIF Biological Term Annotations 1.0 null GTEX-S341-1726-SM-3K2AK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18221 primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.30322 Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86098 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null Posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37152 nephropathy GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAPAN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE125219,GSE125221_5_v_0_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null CPSF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92679 PK45H CCLE Cell Line Gene CNV Profiles -1.0 -1.64312 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00952 Perturb_12544_KO_Ctnnb1_SRP194249 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.4538 GSE62843,GSE64371_4_v_0_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null Extrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.334 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null chr1_69610386_C_A_b38 GTEx eQTL 2025 1.0 5.794 RT4 COSMIC Cell Line Gene Mutation Profiles 1.0 null DHX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5117 Liver GTEx Tissue Gene Expression Profiles 2023 1.0 2.51519 microfilament-proteins Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 1.83692 Attention Deficit Disorder with Hyperactivity HuGE Navigator Gene-Phenotype Associations 1.0 null GSE173201_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ERF::NHLH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.4448 Perturb_15867_KD_KDM3A_SRP248023 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.33986 Lung squamous cell carcinoma_LUSC_TCGA-85-8288-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null TBCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92253 GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.9562 hsa-miR-548b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Nafamostat (mesylate)_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0285741 RERF-LC-MS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16367 UMUC13 DepMap CRISPR Gene Dependency 1.0 2.11362 GSE145215_0_v_3_krt13_mouse RummaGEO Gene Perturbation Signatures 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6488 developmental disorder of mental health GWASdb SNP-Disease Associations 1.0 0.163701 FDX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1675 Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55213 decreased prepulse inhibition MPO Gene-Phenotype Associations 1.0 null SW579 CCLE Cell Line Gene Expression Profiles -1.0 -1.61393 CDK1 KEA Substrates of Kinases 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 2.24651 Kidney Chromophobe_KICH_TCGA-KL-8326-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF610 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 87.8734 GCT CCLE Cell Line Gene Mutation Profiles 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052221 molecular_function GO Molecular Function Annotations 2015 1.0 null cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.61654 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040806 Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.738 GSE173201_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.996669 TBC1D9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06743 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24169 Intravascular large B-cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.04 Specific granule lumen COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null Human - Fetal Development - L2 - Cerebrum-Excitatory neurons HuBMAP Azimuth Cell Type Annotations 1.0 null PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_upregulated_HEY2 Rummagene Transcription Factor Associations 2026 1.0 null T47D_BREAST CCLE Cell Line Proteomics 1.0 2.73248 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37827 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76763 NDUFA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66123 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97586 ACTR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16266 statistically GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.72233 GSE138001_5_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null plausible GeneRIF Biological Term Annotations 1.0 null microtubule cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE126345_4_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.672 GSE77795_0_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S4Z8-0426-SM-3K2AH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988975 DNTTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07104 spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196339 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.6478 MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4694 Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2171 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.7268 Posaconazole_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0315249 podocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.290295 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3834 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.13832 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07233 Membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.551 GSE202310_1_v_0_ube3d_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC11079006-41467_2024_48118_MOESM7_ESM.xlsx-E2F6_OE_vs_EGFP_CTR_DE-gene_E2F6 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.62759 GSE131649_4_v_8_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -2.0671 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1842 IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.966837 increased locomotor activity MGI Mouse Phenotype Associations 2023 1.0 null 4EGI-1_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0246883 Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07803 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17808 Perturb_9048_OE_PRRX1B_SRP168742 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.9706 CUL3 Pathway Commons Protein-Protein Interactions 1.0 null GSE179880_8_v_5_e2f4_mouse RummaGEO Gene Perturbation Signatures 1.0 null bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.854378 hsa-miR-3074-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.404082 Cocaine Dependence DisGeNET Gene-Disease Associations 1.0 null GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 1.24821 GSE111660_1_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22059 MRPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25342 Perturb_13602_KD_AREG_SRP059835 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 protein localization to membrane GO Biological Process Annotations 2025 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993247 Bipolar Disorder DisGeNET Gene-Disease Associations 1.0 null GSE180185_4_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.95065 SNUC4 CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4884-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased total tissue mass MPO Gene-Phenotype Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195568_2_v_4_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Hair root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.599 POLR1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88402 Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dystonia DisGeNET Gene-Phenotype Associations 1.0 null nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04725 MZ in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4908 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25512 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958865 GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13584 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.888783 CSNK2A1 Hub Proteins Protein-Protein Interactions 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testicular GeneRIF Biological Term Annotations 1.0 null sema3a GeneRIF Biological Term Annotations 1.0 null CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03279 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.277 attention deficit hyperactivity disorder GWASdb SNP-Disease Associations 1.0 1.07599 Podocyte foot COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.523 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.23197 Excitatory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.972 NCI-H187 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE136311_1_v_0_lyz2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE195559_3_v_1_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62124 iialphabeta GeneRIF Biological Term Annotations 1.0 null Nuclear membrane microtubule tethering complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.094 Basolateral plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Montelukast DeepCoverMOA Drug Mechanisms of Action 1.0 0.26 GTEX-SUCS-0626-SM-32PM5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.947141 Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22931 Neuron spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.952 GSE62843,GSE64371_2_v_5_furan_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE154337_0_v_1_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-636 TargetScan Predicted Conserved microRNA Targets 1.0 0.154935 NB6 DepMap CRISPR Gene Dependency 1.0 4.07188 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null several GeneRIF Biological Term Annotations 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.970578 IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27048 SNU738 CCLE Cell Line Gene CNV Profiles -1.0 -2.17632 Paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21068 GTEX-OOBK-0526-SM-2HMJJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29065 abnormal behavior MPO Gene-Phenotype Associations 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Criduchat TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.017 kinase GeneRIF Biological Term Annotations 1.0 null Berbamine (dihydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.024836 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6909 CHP212 CCLE Cell Line Gene Expression Profiles 1.0 1.6519 Imiquimod (hydrochloride)_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0161924 renal corpuscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.182994 intralaminar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20587 Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03727 GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PodNet: protein-protein interactions in the podocyte(Mus musculus) WikiPathways Pathways 2014 1.0 null GTEX-T5JC-2426-SM-3NMDB GTEx Tissue Sample Gene Expression Profiles 1.0 1.16251 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.57773 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053643 GTEX-TMMY-1126-SM-4DXSX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61061 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11425 GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3562 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44676 GTEX-X4XX-0011-R8B-SM-46MWM GTEx Tissue Sample Gene Expression Profiles 1.0 0.869152 Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.94083 GTEX-SNMC-1626-SM-4DM52 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85535 GTEX-SNOS-0426-SM-32PMH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00645 GSE119978,GSE180930_2_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TAK-901_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0166305 GTEX-RU72-1126-SM-2TF6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.834812 NCI-H2291 COSMIC Cell Line Gene Mutation Profiles 1.0 null Movement disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46285 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55655 Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04147 Meiotic nuclear membrane microtubule tethering complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.094 Synapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896982 RNF2 ChEA Transcription Factor Targets 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17216 GTEX-WZTO-0011-R7B-SM-4E3IS GTEx Tissue Sample Gene Expression Profiles 1.0 1.04558 head of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11009 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.428891 synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.871346 ChIP_ESRRB_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE127916_1_v_4_nras_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22392 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67166 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.063002 Nerve TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 GSE171179,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null Cervical ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.151 intermediate stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20119 Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null colocalized GeneRIF Biological Term Annotations 1.0 null GSE68156_0_v_1_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCIH1435 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE119978,GSE180930_0_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.948552 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null among GeneRIF Biological Term Annotations 1.0 null VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12163 GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865334 NCSTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22683 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831595 Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_F81L_vs_wt-Gene_Symbol_THAP1 Rummagene Transcription Factor Associations 2026 1.0 null QGP1 CCLE Cell Line Gene Expression Profiles 1.0 1.84966 complexes GeneRIF Biological Term Annotations 1.0 null GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null GI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4186 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25262 GTEX-R53T-1626-SM-3GAEW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856015 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AU565 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10746608-427_2023_709_MOESM4_ESM.xlsx-NR3C1_targets_enrichment-Unnamed_22_NR3C1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null 4-Methylhistamine DeepCoverMOA Drug Mechanisms of Action 1.0 0.58 NCIH838 CCLE Cell Line Gene Mutation Profiles 1.0 null TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.03436 Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.022 Dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.029 phosphorylation GeneRIF Biological Term Annotations 1.0 null HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE181513_2_v_1_usp7_human RummaGEO Gene Perturbation Signatures -1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.3557 Secretory vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.24568 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.943692 Budesonide_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0201562 GTEX-X4XY-1726-SM-46MVO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89057 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83317 Ionotropic glutamate receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.522 hsa-miR-935 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-QVUS-2826-SM-3GADB GTEx Tissue Sample Gene Expression Profiles 1.0 0.964479 Perturb_9111_OE_FOXO1A3_SRP188991 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.33398 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838288 vascular disease GWASdb SNP-Disease Associations 1.0 0.135779 hsa-miR-4511 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 abnormal behavior MGI Mouse Phenotype Associations 2023 1.0 null JARID2-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE229070,GSE229071_0_v_2_sotorasib_human RummaGEO Drug Perturbation Signatures 1.0 null limb grasping MPO Gene-Phenotype Associations 1.0 null neurotransmitter receptor transport, endosome to postsynaptic membrane GO Biological Process Annotations 2025 1.0 null icSARS CoV_30Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.24569 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 GTEX-N7MS-0011-R4a-SM-2HMKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.958146 SOX9 JASPAR Predicted Transcription Factor Targets 1.0 null MZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987695 LN-405 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.97375 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04193 RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7879 NCI-H441 COSMIC Cell Line Gene Mutation Profiles 1.0 null TBL1Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84218 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 3.8916 GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles 1.0 1.10216 Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary system disease GWASdb SNP-Disease Associations 1.0 0.201449 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12266 GSE163052,GSE163198_2_v_7_hira_mouse RummaGEO Gene Perturbation Signatures -1.0 null PRDM16-22522345-PALATE_MESENCHYMAL-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null Paclitaxel_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0184717 RMC-6236_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0367473 Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.586 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.1147 GTEX-S7SF-2126-SM-3K2B2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916277 SC-247 (CCNE1) NURSA Protein Complexes 1.0 null Perturb_4365_KO_UTX/JMJD3_SRP158713 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.955303 GTEX-P44H-0526-SM-2XCF1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881983 GTEX-TSE9-0011-R4A-SM-3DB7H GTEx Tissue Sample Gene Expression Profiles 1.0 1.09734 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76389 GSE103309_2_v_0_ube3a_human RummaGEO Gene Perturbation Signatures -1.0 null Intermediodorsal nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22034 Psychological Tests HuGE Navigator Gene-Phenotype Associations 1.0 null GSE126345_7_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null increased thigmotaxis MGI Mouse Phenotype Associations 2023 1.0 null r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.32097 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-XYKS-1826-SM-4E3JV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45971 POU5F1 ChEA Transcription Factor Targets 1.0 null CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nuclear envelope lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.297 J82 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.53121 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28372 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reduced long-term depression MGI Mouse Phenotype Associations 2023 1.0 null GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20134 GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.824871 chr1_69568580_C_G_b38 GTEx eQTL 2025 1.0 2.20542 SNU840 CCLE Cell Line Gene CNV Profiles 1.0 2.43003 GTEX-TKQ1-0326-SM-4DXSM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867192 TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CA46 CCLE Cell Line Gene Mutation Profiles 1.0 null NCI-H747 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.32514 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.59582 r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00917 Presynaptic actin cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.758 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34369 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.581504 Diammonium Glycyrrhizinate_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0231277 PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComUP-List-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00465 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Renal glomerular capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.605 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49181 FGFR3_knockdown_173_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.48932 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 hsa-miR-2392 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Integrin alpha3-beta1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.82 TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9722 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null INCB 3284 DeepCoverMOA Drug Mechanisms of Action 1.0 0.41 establishment or maintenance of epithelial cell apical/basal polarity GO Biological Process Annotations 2025 1.0 null 5-Fluorouracil_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0247696 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.42888 GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.838288 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 ethmoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33854 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16049 NOXO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88774 abnormality of extrapyramidal motor function GWASdb SNP-Phenotype Associations 1.0 0.704609 COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-S33H-0008-SM-4AD6C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.910347 TMA16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31861 hsa-miR-3200-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null TFDP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1076 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.14764 SN12C Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.54106 thyroid GTEx Tissue Gene Expression Profiles 1.0 0.956039 K562_UNC0379_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0200378 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37758 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837765 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.6668 PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 3.14869 GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.2968 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00588 abnormal reflex MPO Gene-Phenotype Associations 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.864665 primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3838 Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.70247 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.856952 NCI-H2347 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.12356 NCIH1651 CCLE Cell Line Gene Mutation Profiles 1.0 null Perturb_15371_KD_TP53_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.931943 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202587_1_v_2_xrn1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96073 abnormal aggression-related behavior MPO Gene-Phenotype Associations 1.0 null GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.857168 Perturb_17623_KO_PTPN14_SRP153109 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.08244 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67855 Large latent transforming growth factor-beta complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.679 CTNNB1 Hub Proteins Protein-Protein Interactions 1.0 null GSE118766_2_v_0_ifng_mouse RummaGEO Gene Perturbation Signatures 1.0 null vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.892085 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2913 Pitavastatin (Calcium)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0252101 GTEX-X585-0011-R5A-SM-46MVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.31016 GTEX-OOBK-0625-SM-3LK5P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39375 GATA2-19941826-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null junction GeneRIF Biological Term Annotations 1.0 null HCT116 CCLE Cell Line Gene Mutation Profiles 1.0 null oral mucosa HPA Tissue Protein Expression Profiles -1.0 -0.865861 Postsynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.513 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JM1 DepMap CRISPR Gene Dependency 1.0 4.40302 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Human - Fetal Development - L1 - Excitatory neurons HuBMAP Azimuth Cell Type Annotations 1.0 null Orofacial clefts GWAS Catalog SNP-Phenotype Associations 1.0 0.104568 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.192 GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 1.7858 MTF2 ChEA Transcription Factor Targets 1.0 null GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06472 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.25204 OCILY10 CCLE Cell Line Gene Mutation Profiles 1.0 null TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8433 SUZ12 ChEA Transcription Factor Targets 1.0 null BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.64204 GSE206516,GSE206518_2_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null SLR24 DepMap CRISPR Gene Dependency 1.0 2.9923 GSE119498_0_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Human - Fetal Development - L1 - Inhibitory neurons HuBMAP Azimuth Cell Type Annotations 1.0 null GTEX-TMMY-0526-SM-33HBC GTEx Tissue Sample Gene Expression Profiles 1.0 0.929165 LN-18 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.44879 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40806 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1 Rummagene Transcription Factor Associations 2026 1.0 null Neostriatal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.551 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null X-linked dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842842 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980219 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-N7MS-0011-R7a-SM-2HMKN GTEx Tissue Sample Gene Expression Profiles 1.0 0.96375 vesicle-mediated transport GO Biological Process Annotations 2023 1.0 null FARSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37292 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91312 lymph node HPA Tissue Protein Expression Profiles 1.0 0.88223 Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75185 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0602 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68179 Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Fluvoxamine (maleate)_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0262038 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null GTEX-NPJ7-0011-R4a-SM-2I3GJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.891569 abnormality of movement GWASdb SNP-Phenotype Associations 1.0 0.332291 cell-cell junction GO Cellular Component Annotations 2023 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Perturb_12367_KD_SLC39A7_SRP274341 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 16.9555 PMC12443547-DataSheet5.pdf-3-WT1_1_WT1 Rummagene Transcription Factor Associations 2026 1.0 null mania GWASdb SNP-Phenotype Associations 1.0 0.854378 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.42787 H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30616 MFE296 DepMap CRISPR Gene Dependency 1.0 2.59075 PMC6815046-13073_2019_678_MOESM4_ESM.xlsx-MYT1L-Unnamed_0_MYT1L Rummagene Transcription Factor Associations 2026 1.0 null COG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08207 LU99 CCLE Cell Line Gene Expression Profiles 1.0 2.47532 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.978819 hsa-miR-548a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42518 APEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38739 thyroid_5d HPA Tissue Sample Gene Expression Profiles 1.0 1.17078 abnormal spatial reference memory MPO Gene-Phenotype Associations 1.0 null Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.34 RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.097863 SARS-BatSRBD_Day4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.17103 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73109 neurotransmitter receptor transport postsynaptic membrane to endosome GO Biological Process Annotations 2023 1.0 null obesity GWASdb SNP-Disease Associations 1.0 1.02476 urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070672 GSE224969,GSE224971_3_v_5_chtop_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-X4EO-0126-SM-3P5YN GTEx Tissue Sample Gene Expression Profiles 1.0 0.864803 GTEX-XOTO-0011-R8A-SM-4B65J GTEx Tissue Sample Gene Expression Profiles 1.0 0.861775 postsynaptic density GO Cellular Component Annotations 2023 1.0 null GSE131649_4_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE224096_3_v_0_cocaine_human RummaGEO Drug Perturbation Signatures 1.0 null Dendritic spine head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.456 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72245 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14909 GSE62843,GSE64371_4_v_5_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.89376 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.28749 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929094 GSE229973_4_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null MED28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37767 SUZ12-18974828-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17352 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.16102 GSE195513_0_v_3_cpeb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null KP3 CCLE Cell Line Gene Mutation Profiles 1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null NCIH2126 CCLE Cell Line Gene Mutation Profiles 1.0 null Limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56497 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.74258 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19176 CHCHD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01019 SKOV3 CCLE Cell Line Gene Expression Profiles -1.0 -1.48763 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.60659 NCIH727 CCLE Cell Line Gene Mutation Profiles 1.0 null Mediodorsal nucleus of the thalamus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32231 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48758 GSE224969,GSE224971_0_v_1_chtop_mouse RummaGEO Gene Perturbation Signatures -1.0 null MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69037 Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.785 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.0989 GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles 1.0 1.00744 GSE195568_1_v_10_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.59144 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02435 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null 496100416_FWM_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.334 abnormal locomotor activation MPO Gene-Phenotype Associations 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16537 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08691 Volasertib_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0158257 PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null outer CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.901533 binding GO Molecular Function Annotations 2015 1.0 null mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72173 Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28914 hsa-miR-548y TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 K562_Tazemetostat_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0150241 outer CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.85128 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06739 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU3F2 ChEA Transcription Factor Targets 1.0 null Postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.982 CMLT1 CCLE Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4659a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 MBOAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72352 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.19516 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20182 HEC6 CCLE Cell Line Gene Mutation Profiles 1.0 null NCI-H838 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.866452 G402 DepMap CRISPR Gene Dependency 1.0 2.74061 Amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DOV13 CCLE Cell Line Gene CNV Profiles 1.0 1.67653 GSE89018_6_v_14_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Benztropine (mesylate)_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0159598 H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38726 GSE213588_8_v_11_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null NG25_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0174165 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.361659 Familial nephrotic syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.327 hsa-miR-4738-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Breast osteosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.243 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96372 GSE120612_7_v_1_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72796 Spermatheca TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.985 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1315 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04508 PMC10291819-13287_2023_3380_MOESM11_ESM.pdf-35-HMGN3_HMGN3 Rummagene Transcription Factor Associations 2026 1.0 null KMS20 CCLE Cell Line Gene CNV Profiles -1.0 -1.53516 thyroid_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.883912 Diphenhydramine_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0200032 HCC202 COSMIC Cell Line Gene Mutation Profiles 1.0 null 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51592 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.506757 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13042 anterior pretectal nucleus, dorsal superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09034 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_14908_OE_PLZF_SRP127511 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.05507 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 0.938652 AR-19668381-PC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO792 CCLE Cell Line Gene Mutation Profiles 1.0 null kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046441 PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9 Rummagene Transcription Factor Associations 2026 1.0 null Temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE195568_3_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null Azurophil granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.616 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05361 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039619 densin GeneRIF Biological Term Annotations 1.0 null NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7521 GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.89592 GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles 1.0 1.32046 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC14 CCLE Cell Line Gene Mutation Profiles 1.0 null MEG-01 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 GTEX-PLZ6-1326-SM-3NB24 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.94854 heart muscle HPA Tissue Protein Expression Profiles -1.0 -2.87788 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.839551 EVSAT CCLE Cell Line Gene Mutation Profiles 1.0 null r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08542 autoantibodies GeneRIF Biological Term Annotations 1.0 null PMC5319840__SF3_2 PFOCR Pathway Figure Associations 2023 1.0 null GSE94814_2_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.937331 GSE111385_0_v_3_tgfbr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null K562_SL-327_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0174903 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02359 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5956 GTEX-N7MS-0011-R1a-SM-2HMJG GTEx Tissue Sample Gene Expression Profiles 1.0 1.13106 Attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.588 cerebellar cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28843 MM1S COSMIC Cell Line Gene Mutation Profiles 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.666402 CA46 COSMIC Cell Line Gene Mutation Profiles 1.0 null RNF2-18974828-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47819 GSE198982,GSE198986_1_v_2_daunorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46313 premature death MPO Gene-Phenotype Associations 1.0 null facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.995468 Tadalafil_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0170264 RPS4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71963 GSE157555,GSE157556_3_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null nephron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.113865 Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SNU886 CCLE Cell Line Gene Expression Profiles 1.0 1.70965 GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39485 hsa-miR-1304 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 essential hypertension DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.464771 Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12861 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 1.60665 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20227 cell-substrate adherens junction COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 hsa-miR-568 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 GSE139948_3_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Koelliker-Fuse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07243 ADGRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64942 HS944T_SKIN CCLE Cell Line Proteomics 1.0 4.01692 GLI4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33447 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09579 NSMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04214 PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null Sympathetic ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.912 stomach HPA Tissue Gene Expression Profiles -1.0 -0.955515 GSE166783_8_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null synapse COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.484 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38563 PMC9314667-Table_1.xlsx-Regulons-IRF7_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null wild GeneRIF Biological Term Annotations 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.884285 cell part GO Cellular Component Annotations 2015 1.0 null glomerular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.268482 kirrel GeneRIF Biological Term Annotations 1.0 null BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7503 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null ALEXANDERCELLS CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07344 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.85538 FARAGE DepMap CRISPR Gene Dependency 1.0 2.6481 c-MYC_KD_GDS2526_109_human_Hela cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null sub-surface cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.531 AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44222 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.324257 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NVP-BHG712_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0205395 Ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 UACC-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null Verapamil_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0177644 SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Metyrapone DeepCoverMOA Drug Mechanisms of Action -1.0 -0.39 Pyridoxine (hydrochloride)_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.017791 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null Major depressive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 Medial dorsal nucleus of thalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.863 GSE130081,GSE130082_5_v_10_neil2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU213 CCLE Cell Line Gene Expression Profiles -1.0 -1.63453 Obesity-related traits GWAS Catalog SNP-Phenotype Associations 1.0 0.070053 contacts GeneRIF Biological Term Annotations 1.0 null Dexamethasone_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0232582 Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.47716 hsa-miR-3924 TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 calcium- and calmodulin-dependent protein kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.852 RHOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0041 H3K27me3_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_SUZ12_18974828 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07225 growth/size/body phenotype MPO Gene-Phenotype Associations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5744-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9614 variants GeneRIF Biological Term Annotations 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01057 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.417 AR ChEA Transcription Factor Targets 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44474 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 1.81592 GSE126127_5_v_4_prmt1_mouse RummaGEO Gene Perturbation Signatures -1.0 null mediodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1825 GTEX-WWYW-0011-R1A-SM-3TW8G GTEx Tissue Sample Gene Expression Profiles 1.0 1.37602 RT4 CCLE Cell Line Gene Mutation Profiles 1.0 null MYOD1 ENCODE Transcription Factor Targets 1.0 null brain GTEx Tissue Gene Expression Profiles 1.0 2.00986 GSE80446_2_v_1_anakinra_mouse RummaGEO Drug Perturbation Signatures -1.0 null Hippocampal mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.927 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.02405 psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.571107 hsa-miR-300 TargetScan Predicted Conserved microRNA Targets 1.0 0.123298 dorsal subnucleus of MG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15122 GSE195503_1_v_2_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null IALM CCLE Cell Line Gene CNV Profiles 1.0 1.52625 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.57276 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.48194 GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02382 gallbladder HPA Tissue Gene Expression Profiles 1.0 0.881014 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01561 Lewy body-like hyaline inclusion COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.568 RPS19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1037 hsa-miR-3163 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-N7MS-0011-R5a-SM-2HMK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41657 GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles 1.0 0.89159 Anchoring junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 postnatal lethality MGI Mouse Phenotype Associations 2023 1.0 null establishment of protein localization to organelle GO Biological Process Annotations 2023 1.0 null intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles 1.0 1.2502 Lung adenocarcinoma_LUAD_TCGA-49-6743-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2066 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -1.87358 reduced long term depression MPO Gene-Phenotype Associations 1.0 null KOPN8 CCLE Cell Line Gene Expression Profiles -1.0 -1.90556 GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31143 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35006 Postsynaptic density COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Bicellular tight junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.26 synaptic membrane GO Cellular Component Annotations 2015 1.0 null medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10441 GTEX-WZTO-0011-R1B-SM-3NMAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.18895 RERFLCKJ CCLE Cell Line Gene CNV Profiles 1.0 1.88991 Dabrafenib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0350032 Chromosomal deletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.466 cell-cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE111660_4_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH510 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13137 NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.899238 GSE100102_0_v_5_cgas_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-1276 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 GTEX-T5JC-0011-R5A-SM-32PLK GTEx Tissue Sample Gene Expression Profiles 1.0 1.24393 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8371 CME1 DepMap CRISPR Gene Dependency 1.0 2.17396 ESRRB-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null CORL24 CCLE Cell Line Gene Mutation Profiles 1.0 null amygdala TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.317456 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96259 18801183-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null Diabetic Nephropathies HuGE Navigator Gene-Phenotype Associations 1.0 null NCIH446 CCLE Cell Line Gene Mutation Profiles 1.0 null ZBTB43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57218 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1271 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Lung adenocarcinoma_LUAD_TCGA-91-8497-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09231 GSE113106_2_v_1_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null KCNF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8835 MELJUSO CCLE Cell Line Gene Mutation Profiles 1.0 null attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null HPBALL CCLE Cell Line Gene CNV Profiles -1.0 -2.06359 Perturb_14526_KO_Foxa2/Gata4_SRP111204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20541 CHEMBL2431803 DeepCoverMOA Drug Mechanisms of Action 1.0 0.22 GSE217363_0_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU1066 CCLE Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_17365_Mut|OE_Sik3E13_SRP334442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -15.1132 Microtubule cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.484 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837765 GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures -1.0 null PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837765 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42578 GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.25597 telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WHSE-0011-R7A-SM-3P5YZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.41488 GSE172019_2_v_8_rnf2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56049 GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles 1.0 1.09812 Cocaine Abuse DisGeNET Gene-Disease Associations 1.0 null IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831258 GSE195503_3_v_0_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null thyroid gland HPA Tissue Protein Expression Profiles 1.0 1.77778 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Entrectinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.00862873 GSE157555,GSE157556_0_v_1_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null dehydration MGI Mouse Phenotype Associations 2023 1.0 null D-245MG Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.51542 neurons Phosphosite Textmining Biological Term Annotations 1.0 null GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40754 PATZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14501 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10079 Spine synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.163 ES4 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.38083 Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null PRIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82182 GTEX-OHPN-0011-R1A-SM-2I5GB GTEx Tissue Sample Gene Expression Profiles 1.0 0.879967 cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3323-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1666_LUNG CCLE Cell Line Proteomics 1.0 6.22453 GSE161170,GSE161268_1_v_3_med1_human RummaGEO Gene Perturbation Signatures 1.0 null Cardiofaciocutaneous syndrome 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.028 Basal plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 hsa-miR-338-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 Musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bergenin_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0159245 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.18954 not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Proximal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.853 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null cell-cell junction GO Cellular Component Annotations 2025 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054465 GSE174701_4_v_8_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null ZKSCAN5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.3616 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.709915 Muscular Dystrophy DisGeNET Gene-Disease Associations 1.0 null 769-P COSMIC Cell Line Gene Mutation Profiles 1.0 null PPARD ChEA Transcription Factor Targets 1.0 null Postsynaptic specialization COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875065 ATM_KD_GSE54268_661_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.87707 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.02285 TGW Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -5.05464 NDUFAF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51049 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Signal Transduction Reactome Pathways 2024 1.0 null CDK13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16476 salivarygland_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.0167 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09075 HEL9217 CCLE Cell Line Gene Expression Profiles 1.0 2.10205 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14319 K562_Danusertib_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0162372 GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.01043 abnormality of humoral immunity GWASdb SNP-Phenotype Associations 1.0 0.704609 hsa-miR-410 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 PMC4686785__F8 PFOCR Pathway Figure Associations 2023 1.0 null cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16082 hsa-miR-4468 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.856 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KML1 DepMap CRISPR Gene Dependency 1.0 5.62603 ganglion TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COLO818 CCLE Cell Line Gene Mutation Profiles 1.0 null endometrium HPA Tissue Protein Expression Profiles -1.0 -0.865861 ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.5157 GSE119978,GSE180930_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null positive regulation of cell projection organization GO Biological Process Annotations 2025 1.0 null superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62541 exons GeneRIF Biological Term Annotations 1.0 null GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.623 GTEX-Q2AH-0826-SM-48TZN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.839904 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAK-733_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0196873 abnormal motor capabilities/coordination/movement MPO Gene-Phenotype Associations 1.0 null TK10 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U8T8-0326-SM-3DB93 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.834341 contribute GeneRIF Biological Term Annotations 1.0 null W-13 HCl DeepCoverMOA Drug Mechanisms of Action 1.0 0.33 Main axon COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Perturb_4217_OE_Hoxa2_SRP092451 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.15392 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_14348_KD_CDK12_SRP223931 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 ChIP_RNF2_22325148 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27978 trans-synaptic protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.579 GTEX-U4B1-1726-SM-3DB9F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40593 Perturb_7336_KD_SUGP1_SRP286876 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.58967 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.247854 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.34285 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.4247 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052722 hypertension GWASdb SNP-Disease Associations 1.0 1.37327 PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null BFTC905 CCLE Cell Line Gene Expression Profiles -1.0 -1.62778 CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.853593 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43619 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.91345 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Presynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.595 PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null GRIN2B Pathway Commons Protein-Protein Interactions 1.0 null iPS-20b Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.70999 Perturb_6746_KO|KD_UPF3B|UPF3A_SRP327782 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.33093 GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23055 GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10441 BICR18 CCLE Cell Line Gene Mutation Profiles 1.0 null OCI-AML5 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE220520_6_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null SJSA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null diabetes mellitus, type 1; diabetic nephropathies GAD Gene-Disease Associations 1.0 null GTEX-OHPL-1326-SM-3MJGG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0285 stip1 GeneRIF Biological Term Annotations 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SCLC21H CCLE Cell Line Gene Expression Profiles 1.0 1.43088 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH1573 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE150669_0_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures -1.0 null Filtration diaphragm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.012 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70358 Sertoli cell tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null GSE82032_3_v_1_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null ACTN4 Pathway Commons Protein-Protein Interactions 1.0 null Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.273 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.062813 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07233 Breast liposarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.298 Integrin alphav-beta8 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.56 GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.95169 HS606T CCLE Cell Line Gene Expression Profiles -1.0 -2.39514 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1424 Silodosin_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0103476 GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38955 Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_17360_OE_HDAC4_SRP334442 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.5778 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26454 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.856863 Podocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.617 Organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.573 GSE210682_0_v_3_methadone_human RummaGEO Drug Perturbation Signatures 1.0 null RPP38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75424 adherens junction COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CADO-ES1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.15582 GSE147876,GSE147877_2_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE120612_7_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null Cabozantinib (S-malate)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0247673 Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932032 Delamanid_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0178906 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89093 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_3514_KD_RNPS1_ERP130704 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 9.16196 Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.807 CTB-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HDLM-2 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.19649 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 TP53-18474530-U2OS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.62697 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40806 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04985 SK-MEL-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QDT8-0008-SM-48U2F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05844 UACC-257 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03838 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.046148 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.921546 neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.775471 HC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35726 MYOD1_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4828 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867286 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27875 Nephrocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.845 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null Perturb_9113_OE_FOXO1A3_SRP188991 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.23977 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3369 DBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41309 stomach_3b HPA Tissue Sample Gene Expression Profiles -1.0 -1.08822 GTEX-OOBK-0126-SM-2YUND GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832753 ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-3921 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 UBE2L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19969 Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17132 GSE163240_2_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null NZOV9 DepMap CRISPR Gene Dependency 1.0 3.27014 PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Negative regulation of NMDA receptor-mediated neuronal transmission Reactome Pathways 2024 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null Postsynapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.417 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.212138 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-576-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 MDA-MB-330 COSMIC Cell Line Gene CNV Profiles -1.0 -3.32901 superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01706 MC116 CCLE Cell Line Gene Mutation Profiles 1.0 null GATA1 ChEA Transcription Factor Targets 1.0 null SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79953 KYSE150 CCLE Cell Line Gene Expression Profiles 1.0 2.43236 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBK-0425-SM-3LK5O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852724 Human - Motor Cortex - Cluster - RORB+ MED8+ Layer 5 glutamatergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null Mediodorsal nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23499 JHH2 CCLE Cell Line Gene CNV Profiles 1.0 2.12582 podocytes GeneRIF Biological Term Annotations 1.0 null Perturb_12515_KD_TRA2B_SRP221583 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 4.54249 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.898298 Pluteus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.016 external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29307 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -4.1852 Organelle envelope lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.962 Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.9483 Homoharringtonine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0252145 GTEX-RU72-0011-R6A-SM-2TF71 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17284 ELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68864 PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GSE126345_2_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null increased thigmotaxis MPO Gene-Phenotype Associations 1.0 null EML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28329 Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14625 Melancholic depression DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.024 hsa-miR-1193 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05118 hsa-miR-3130-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 GATA2-19941826-K562-human ChEA Transcription Factor Binding Site Profiles 1.0 null GSE164874_5_v_2_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76161 NCIH2126 CCLE Cell Line Gene CNV Profiles 1.0 1.35543 membranes GeneRIF Biological Term Annotations 1.0 null olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Torkinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0380102 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41672 K562 CCLE Cell Line Gene Mutation Profiles 1.0 null WSU-NHL COSMIC Cell Line Gene Mutation Profiles 1.0 null ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null GSE171837_3_v_1_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null PD 160170 DeepCoverMOA Drug Mechanisms of Action -1.0 -0.69 kidney disease GWASdb SNP-Disease Associations 1.0 0.858922 GSE216273,GSE216292_14_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null EW-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19374 TP53-23651856-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE149075_8_v_11_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WFON-0426-SM-3GIL4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846365 Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05084 Doxorubicin (hydrochloride)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0240942 Postsynaptic specialization COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.521 abnormal nervous system physiology MPO Gene-Phenotype Associations 1.0 null GSE133087_5_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Candidiasis DisGeNET Gene-Disease Associations 1.0 null MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE126345_9_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 CTNND2 Pathway Commons Protein-Protein Interactions 1.0 null GSE149096_4_v_3_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.07 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.439 Lonafarnib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0257587 specific granule GO Cellular Component Annotations 2025 1.0 null regulation of neuron projection development GO Biological Process Annotations 2025 1.0 null GSE97278,GSE97280_2_v_3_nsd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE108614,GSE108615_3_v_2_setd1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null SRY JASPAR Predicted Transcription Factor Targets 1.0 null blood GTEx Tissue Gene Expression Profiles -1.0 -1.95647 PMC6941881-mmc4.xlsx-IR_only_Up_DEGs-List_of_DEGs_that_are_upregulated_upon_PRMT5_KD_only_in_IR_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01551 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837765 GTEX-S32W-2226-SM-2XCAY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.890797 abnormal learning/memory/conditioning MPO Gene-Phenotype Associations 1.0 null INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43321 NCIH1963 CCLE Cell Line Gene Mutation Profiles 1.0 null mortality/aging MPO Gene-Phenotype Associations 1.0 null nervous system phenotype MPO Gene-Phenotype Associations 1.0 null PANC-02-03 COSMIC Cell Line Gene Mutation Profiles 1.0 null RAB3GAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04221 EZH2 ChEA Transcription Factor Targets 1.0 null no-10 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.93127 AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58482 GTEX-S4P3-1526-SM-3K2AV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.923545 GSE209598_1_v_2_tgfbr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.573 GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 1.9542 GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20819 Steatohepatitis DisGeNET Gene-Disease Associations 1.0 null schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.572273 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13114 MAD2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74112 COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02014 Bisphenol A DeepCoverMOA Drug Mechanisms of Action -1.0 -0.45 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.911331 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66801 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.9903 Posterior paraventricular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.868 Perturb_18005_KO_Grn_SRP070945 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.19846 OC316 CCLE Cell Line Gene Mutation Profiles 1.0 null abnormal cns synaptic transmission MPO Gene-Phenotype Associations 1.0 null tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.56739 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27088 non-membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 BV-173 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.931347 Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11798 BAI1 Pathway Commons Protein-Protein Interactions 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 4.06292 GSE239541_11_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17808 Dentate gyrus mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.754 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2619 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Everolimus_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0175175 GTEX-XOTO-3026-SM-4B65M GTEx Tissue Sample Gene Expression Profiles 1.0 0.987115 lung_4d HPA Tissue Sample Gene Expression Profiles -1.0 -1.05201 Lung adenocarcinoma_LUAD_TCGA-69-7765-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SE5C-1126-SM-4BRWZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24029 hypertension GAD Gene-Disease Associations 1.0 null SW1573 DepMap CRISPR Gene Dependency 1.0 2.83646 Sympathetic chain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.882 GTEX-Q2AH-0126-SM-48U2B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871425 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.6261 PMC11192681-11033_2024_9703_MOESM1_ESM.xlsx-common_ZFPs-C2H2-ZNF_genes_commonly_appearing_as_DEGs_WT_vs_SETDB1_KO_cells_in_HAP1_and_293T_cells_SETDB1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49284 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9616830-42003_2022_4093_MOESM3_ESM.csv--Cao2020_SATB2_LRRC7_positive_cells_SATB2 Rummagene Transcription Factor Associations 2026 1.0 null anthrax disease GWASdb SNP-Disease Associations 1.0 0.808756 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11198 Imago TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.828 TBRG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28541 8-Hydroxyquinoline_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.00840195 TOR1A Pathway Commons Protein-Protein Interactions 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.09217 Nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.573 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.41323 GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89407 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE178113,GSE178116_0_v_1_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE214382,GSE214383_4_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.829964 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TO14 DepMap CRISPR Gene Dependency 1.0 2.03366 D-247MG COSMIC Cell Line Gene Mutation Profiles 1.0 null brain_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.32386 Nerve ring TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.768 Basolateral recycling endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.553 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.36463 Balsalazide (sodium hydrate)_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0242645 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120612_4_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.68006 LIM1215 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1 Rummagene Transcription Factor Associations 2026 1.0 null GSE138633_2_v_0_bag3_human RummaGEO Gene Perturbation Signatures 1.0 null GSE103122_0_v_1_puromycin_human RummaGEO Drug Perturbation Signatures 1.0 null 9-ING-41_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0195713 increased body weight GWASdb SNP-Phenotype Associations 1.0 0.899912 Hypodermal seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.911 Medial geniculate complex, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68072 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.706458 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 0.913346 GSE164874_5_v_0_prednisolone_human RummaGEO Drug Perturbation Signatures -1.0 null Nephrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 cell-cell junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.321575 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 0.898154 PMC4595011-pgen.1005555.s002.xlsx-MITF_UP_in_30kb-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null BCPAP CCLE Cell Line Gene CNV Profiles 1.0 1.37825 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.4069 GTEX-R55E-0011-R5A-SM-2TC5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.18494 PK1 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 1.16382 GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null SMARCD1-25818293-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.19024 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75532 Anastrozole_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0144379 abnormal social/conspecific interaction MPO Gene-Phenotype Associations 1.0 null TE1 CCLE Cell Line Gene CNV Profiles -1.0 -2.03759 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01312 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.928556 positive regulation of neuron projection development GO Biological Process Annotations 2023 1.0 null forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.658678 EXOSC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28697 MCUR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20717 Neurod2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 44.4357 DMS-273 COSMIC Cell Line Gene Mutation Profiles 1.0 null specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 hsa-miR-548f TargetScan Predicted Conserved microRNA Targets 1.0 0.23348 Perturb_15370_KD_TP53_SRP294453 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SBI-0640756_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0237726 ChIP_JARID2_20075857 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_12546_KO_Shank2_SRP309197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.43174 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4339 HCT15 DepMap CRISPR Gene Dependency 1.0 2.62974 GTEX-OHPL-0426-SM-3TW8X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826443 ATF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43921 BRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31789 PDS5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06508 Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Decitabine_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0238091 Filgotinib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.028511 GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825376 CW2 CCLE Cell Line Gene Mutation Profiles 1.0 null Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.38378 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.902361 GSE102675_3_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23822 FXR MotifMap Predicted Transcription Factor Targets 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null Axon COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Perturb_4132_OE_PS2APP_SRP092532 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.43 GSE145476_2_v_0_hopx_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 1.328 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.994439 duodenum HPA Tissue Gene Expression Profiles -1.0 -0.955515 Perturb_625_KD_IGF2BP3_SRP068523 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.9226 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.51515 DMS273 CCLE Cell Line Gene Mutation Profiles 1.0 null mammalian phenotype MPO Gene-Phenotype Associations 1.0 null AR-22383394-PROSTATE-CANCER-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MYOG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.3068 C11orf96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17303 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34345 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51194 K562_S-Ruxolitinib_10然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0169069 CAMK2A Hub Proteins Protein-Protein Interactions 1.0 null K562_Tozasertib_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0150302 lateral (parvicellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15072 CAMK2A KEA Substrates of Kinases 1.0 null Synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.948 MFE280 CCLE Cell Line Gene CNV Profiles 1.0 1.50438 NCIH2029 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06581 Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPL19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.11983 PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4 Rummagene Transcription Factor Associations 2026 1.0 null Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32543 internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.0675 SLVL Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.79418 GSE254649_3_v_1_cstf2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-VJYA-1326-SM-3GIJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21289 developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29968 Glomerular endothelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.773 HCC1937 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mediodorsal nucleus of the thalamus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08202 GTEX-Q2AG-2926-SM-2HMJ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.918321 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.941608 Leucine rich repeat 4 InterPro Predicted Protein Domain Annotations 1.0 null PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-63-FOXD1_FOXD1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2 Rummagene Transcription Factor Associations 2026 1.0 null abnormal prepulse inhibition MPO Gene-Phenotype Associations 1.0 null SC-7898 (CHEK1) NURSA Protein Complexes 1.0 null GSE150055_0_v_2_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTBP2-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE206516,GSE206518_6_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.156863 hsa-miR-4789-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.17031 Zic3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 39.1135 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.818158 GSE231891_1_v_0_cdk8_human RummaGEO Gene Perturbation Signatures -1.0 null avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Gemcitabine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0242991 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14213 K562_Dasatinib_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0140193 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.40519 GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null OVSAHO CCLE Cell Line Gene Mutation Profiles 1.0 null hsa-miR-489 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Phelan-McDermid syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.381 abnormal neurite morphology MGI Mouse Phenotype Associations 2023 1.0 null medial (magnocellular) part of MD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2903 Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.995 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61412 PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null NB1643 DepMap CRISPR Gene Dependency 1.0 2.47705 CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling Reactome Pathways 2024 1.0 null GSE196540,GSE196542_2_v_3_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAFA-gene_MAFA Rummagene Transcription Factor Associations 2026 1.0 null GSE164874_5_v_3_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WL46-0011-R7A-SM-3LK7X GTEx Tissue Sample Gene Expression Profiles 1.0 1.57347 GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18437 GSE115542_5_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857066 NCIH23 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE210101,GSE210114_6_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860459 medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.90186 KM12 CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14531_KO_Ptf1a_SRP111204 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 CCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06999 hsa-miR-15b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.565 Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neurotransmitter receptor transport, endosome to plasma membrane GO Biological Process Annotations 2025 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67D-01A-31R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null GSE149075_3_v_11_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59205 GTEX-QMRM-0626-SM-447BQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11162 SUPHD1 CCLE Cell Line Gene Mutation Profiles 1.0 null TGBC11TKB CCLE Cell Line Gene Mutation Profiles 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.40007 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.044 GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE115542_2_v_3_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1918 GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10458 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77355 Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null decreased body weight MGI Mouse Phenotype Associations 2023 1.0 null membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.573 FADU CCLE Cell Line Gene Mutation Profiles 1.0 null organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE133087_1_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null HCC202 CCLE Cell Line Gene Mutation Profiles 1.0 null ChIP_JARID2_20064375 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Parallel fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.711 EIF4G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43763 MFAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46856 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.47485 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.38307 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null JHH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XUJ4-0126-SM-4BOP7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.928135 GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14374 PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null abnormal nest building behavior MGI Mouse Phenotype Associations 2023 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5765-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33854 Perturb_10112_KD_FXR1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.39399 GTEX-SUCS-1826-SM-32PM1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01879 MTMR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19855 periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23039 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14768 Perturb_9985_KD_U2AF1_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.39393 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null MALME3M CCLE Cell Line Gene Mutation Profiles 1.0 null A3KAW CCLE Cell Line Gene Mutation Profiles 1.0 null postsynaptic density GO Cellular Component Annotations 2025 1.0 null thyroid gland HPA Tissue Gene Expression Profiles 1.0 1.22318 PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9988 Medium spiny neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.133 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.09093 intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59205 GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null NALM6 CCLE Cell Line Gene Expression Profiles 1.0 1.46849 hsa-miR-3143 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-EN2-sequence_name_EN2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-O5YT-0008-SM-4E3IQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.993102 PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_15400_KD_AR_SRP014809 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.21404 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46775 Belzutifan_SNU-1 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0166401 sclc21h HPA Cell Line Gene Expression Profiles 1.0 1.04218 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Somatodendritic compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.007 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06552 SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nuclear inner membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.44 establishment or maintenance of apical/basal cell polarity GO Biological Process Annotations 2025 1.0 null TE-4 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.04928 Fumitremorgin C DeepCoverMOA Drug Mechanisms of Action -1.0 -0.3 Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29989 Asarone DeepCoverMOA Drug Mechanisms of Action 1.0 0.34 obsessive-compulsive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.241 CDYL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11626 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98306 H3K9me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.971591 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31248 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929094 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05113 CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null candidate GeneRIF Biological Term Annotations 1.0 null Perturb_407_OE_DPP4_SRP353826 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49847 GTEX-P4QS-0526-SM-2I3ET GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00716 variant GeneRIF Biological Term Annotations 1.0 null Fusidic acid_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0272389 Brugada syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.095 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24707 JHH2 DepMap CRISPR Gene Dependency 1.0 2.7001 pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.100496 GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0191 GR MotifMap Predicted Transcription Factor Targets 1.0 null GSE210580_0_v_1_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Reticulate body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55238 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98864 UACC257 CCLE Cell Line Gene Mutation Profiles 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053975 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73099 GSE143955_1_v_2_ripk1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Suprageniculate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36015 GSE62843,GSE64371_4_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PRIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52077 GTEX-XBED-1326-SM-4AT4F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38713 RNASEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49067 Perturb_9976_KD_G3BP2_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.72874 Focal adhesion COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.417 Adrenocortical carcinoma_ACC_TCGA-OR-A5JG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MM370 DepMap CRISPR Gene Dependency 1.0 2.32091 RCM1 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE131649_6_v_0_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-4803 TargetScan Predicted Conserved microRNA Targets 1.0 0.159923 GSE111660_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null NKTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04662 Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.167 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX4 MotifMap Predicted Transcription Factor Targets 1.0 null Nucleoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.885 toxic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.266203 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63987 cell-substrate junction COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.856952 SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922931 496100391_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.59594 GTEX-X261-0011-R10B-SM-4E3JT GTEx Tissue Sample Gene Expression Profiles 1.0 0.960044 NCIH1944 CCLE Cell Line Gene Mutation Profiles 1.0 null Perturb_9754_KO_Cfb_SRP333300 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.97035 WBP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36262 GSE131887_5_v_2_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null slit diaphragm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.200328 JARID2-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null plexiform layer of TuPal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15971 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.03771 ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0273 hsa-miR-4299 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4666-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.115091 Spherical high-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 Presynaptic grid COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.884 superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13605 hsa-miR-3117-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 CAS-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.9771 decreased body weight MPO Gene-Phenotype Associations 1.0 null Exocytic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563 Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-16 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Microtubule organizing center attachment site COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.048 Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null impaired coordination MGI Mouse Phenotype Associations 2023 1.0 null Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 COCM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GSE206400_1_v_0_nusinersen_mouse RummaGEO Drug Perturbation Signatures -1.0 null orofacial cleft DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.126165 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950186 hsa-miR-548j TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Nance-Horan syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.283 MBTPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4892 disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.464771 Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06599 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42519 GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 0.981369 adherens junction GO Cellular Component Annotations 2025 1.0 null parkinson's disease GWASdb SNP-Disease Associations 1.0 0.808756 RPMI7951 DepMap CRISPR Gene Dependency 1.0 5.29916 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18575 HEL CCLE Cell Line Gene Expression Profiles 1.0 3.40812 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.55919 ca2+ Phosphosite Textmining Biological Term Annotations 1.0 null abnormal fear/anxiety-related behavior MPO Gene-Phenotype Associations 1.0 null RABGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23662 Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 Perindopril (erbumine)_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0186992 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null PCDHB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18427 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.81495 GSE164505,GSE164506_3_v_1_indisulam_human RummaGEO Drug Perturbation Signatures 1.0 null Tubulin folding cofactor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 TRIM28_knockout_302_GSE32224 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.08465 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.376202 nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 CDH2 Pathway Commons Protein-Protein Interactions 1.0 null positive regulation of neuron projection development GO Biological Process Annotations 2025 1.0 null CA1 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42373 HT55 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-XMD3-0008-SM-4AT4V GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16956 TRAPPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23666 GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 1.08868 WIL2-NS Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.88896 GSE153907,GSE153908_0_v_1_azathioprine_human RummaGEO Drug Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02267 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE248858_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.921418 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33188 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.0409 hsa-miR-4776-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 CTNND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55602 CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05343 P2RX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02947 SIMA Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.68401 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53667 GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE205163,GSE205164_2_v_0_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Larval ventral ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.891 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29423 nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.77778 GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920416 GSE210580_3_v_11_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Activation of NMDA receptors and postsynaptic events Reactome Pathways 2024 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82722 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.66451 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548ak TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 GEMIN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39549 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Cervix - Endocervix GTEx Tissue Gene Expression Profiles 2023 1.0 1.74233 U-2-OS COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE197562_2_v_3_nox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null increased anxiety-related response MPO Gene-Phenotype Associations 1.0 null GSE86507,GSE86509_7_v_10_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.98864 Centrosome COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54394 PMC11408518-41598_2024_73146_MOESM5_ESM.xlsx-Intersection_gene-NCOA1_NCOA1 Rummagene Transcription Factor Associations 2026 1.0 null PC-14 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XOTO-0011-R6B-SM-4B65X GTEx Tissue Sample Gene Expression Profiles 1.0 1.13467 Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pdz Phosphosite Textmining Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-664 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 HLE Sanger Dependency Map Cancer Cell Line Proteomics 1.0 2.73424 GSE121198,GSE129782_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null Cognitive decline rate in late mild cognitive impairment GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.71549 Glomerular endothelium fenestra COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.731 GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.05921 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.979425 GP2D CCLE Cell Line Gene Mutation Profiles 1.0 null abnormal body size MPO Gene-Phenotype Associations 1.0 null Attention deficit hyperactivity disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 hsa-miR-449b TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 Orofacial clefts GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 Bimatoprost_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0278027 ChIP_SUZ12_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.12687 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.166582 GSE229973_3_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-SSA3-0526-SM-32QPL GTEx Tissue Sample Gene Expression Profiles 1.0 0.949363 Ras activation upon Ca2+ influx through NMDA receptor Reactome Pathways 2024 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88Q-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9972 overnutrition GWASdb SNP-Disease Associations 1.0 0.474846 PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2 Rummagene Transcription Factor Associations 2026 1.0 null SJSA1 CCLE Cell Line Gene Mutation Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30663 GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NPJ8-1526-SM-2D7VU GTEx Tissue Sample Gene Expression Profiles 1.0 0.891653 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.202946 NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null EWS502 DepMap CRISPR Gene Dependency 1.0 2.59205 gh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.586 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFC3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16233 GSE206400_1_v_4_nusinersen_mouse RummaGEO Drug Perturbation Signatures -1.0 null HS343T CCLE Cell Line Gene Expression Profiles -1.0 -1.62696 Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.5434 K562_Bosutinib_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0104885 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.109067 GSE126345_7_v_5_hcrt_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15677 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cranial nerve TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4707 PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.958968 superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29989 Obesity-related traits GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A Rummagene Transcription Factor Associations 2026 1.0 null TC71_BONE CCLE Cell Line Proteomics 1.0 2.15903 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24437 Anchoring junction COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.417 GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02303 Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE137144_2_v_0_nlrp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Asymmetric synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.501 Nrf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 73.2654 synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.957352 GSE166783_1_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Septate junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.817 outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922573 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19902 nutrition disease GWASdb SNP-Disease Associations 1.0 0.417062 Striatum dorsal region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08608 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.86568 nerve GTEx Tissue Gene Expression Profiles 1.0 1.16051 hsa-miR-548c-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02895 Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864036 Breast rhabdomyosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 Specific granule COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065212 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11061 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.951 TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null KIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31579 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29328 striatum (corpus striatum) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06536 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825319 COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34664 alpha-subunit Phosphosite Textmining Biological Term Annotations 1.0 null r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03356 M07E CCLE Cell Line Gene Expression Profiles 1.0 1.93216 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.462 KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.81993 cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17418 RARB-27405468-CHIP-SEQ-BRAIN-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86047 TRIM28 ChEA Transcription Factor Targets 1.0 null GTEX-Q2AG-0011-R7A-SM-2HMJP GTEx Tissue Sample Gene Expression Profiles 1.0 1.19319 hmc1 HPA Cell Line Gene Expression Profiles -1.0 -1.0737 MATH1 MotifMap Predicted Transcription Factor Targets 1.0 null Exoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.519 GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE164874_5_v_12_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null NCIH1373 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36652 PMC5319840__F3 PFOCR Pathway Figure Associations 2024 1.0 null NCIH1930 CCLE Cell Line Gene Mutation Profiles 1.0 null periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934286 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null GSE141667_3_v_2_cocaine_mouse RummaGEO Drug Perturbation Signatures 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles -1.0 -0.865861 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH889 CCLE Cell Line Gene Expression Profiles 1.0 1.38092 EJM DepMap CRISPR Gene Dependency 1.0 3.05394 CAMK2G Pathway Commons Protein-Protein Interactions 1.0 null Junctional membrane complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.695 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.89064 vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.464771 thyroid_5c HPA Tissue Sample Gene Expression Profiles 1.0 1.06811 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.97722 GSE89018_6_v_2_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNRNP40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74764 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19741 KIJK DepMap CRISPR Gene Dependency 1.0 8.75845 GSE89018_6_v_8_cry2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 8MGBA CCLE Cell Line Gene CNV Profiles 1.0 1.59903 PMC11873652-mmc1.pdf-4-ETS1_ETS1 Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.83124 T98G Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.59088 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08894 GSE131887_5_v_3_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null Methylthiouracil_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0159784 Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 1.92054 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00819 Fetal Lung Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.03417 CTBP1-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abnormal hippocampal pyramidal neuron dendrite morphology MGI Mouse Phenotype Associations 2023 1.0 null cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.89936 SAP30 ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-1126-SM-3NMBK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981182 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52786 appeear GeneRIF Biological Term Annotations 1.0 null PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9017 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 KNS-81-FD Sanger Dependency Map Cancer Cell Line Proteomics 1.0 3.22325 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35422 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 0.056133 SSSCA1 Pathway Commons Protein-Protein Interactions 1.0 null Glomerular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.613 proteinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.19742 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00588 GSE113106_0_v_5_dnm2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-34c-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 EKVX CCLE Cell Line Gene CNV Profiles -1.0 -2.59442 RH-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormal long term depression MPO Gene-Phenotype Associations 1.0 null Superior cervical ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.165 GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles 1.0 0.99797 ASH3 DepMap CRISPR Gene Dependency 1.0 2.80978 Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMK1-2426-SM-4B66I GTEx Tissue Sample Gene Expression Profiles 1.0 0.93327 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.88865 CNKSR2 Pathway Commons Protein-Protein Interactions 1.0 null GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null parvicellular part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03396 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.00449 GTEX-U8XE-1926-SM-3DB98 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1318 GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875368 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 specific granule GO Cellular Component Annotations 2023 1.0 null GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841657 neurotransmitter receptor transport to postsynaptic membrane GO Biological Process Annotations 2023 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854462 striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.890843 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.873209 abnormal sleep behavior MPO Gene-Phenotype Associations 1.0 null MDCK-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.617 DPH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38528 PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4 Rummagene Transcription Factor Associations 2026 1.0 null nuclear part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041881 GTEX-R55G-2426-SM-2TC5I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37914 IM95 DepMap CRISPR Gene Dependency 1.0 2.07581 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH1048 CCLE Cell Line Gene Mutation Profiles 1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null slit GeneRIF Biological Term Annotations 1.0 null GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 2.22732 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3316-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC1A CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.940146 hsa-miR-4666-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE243491_3_v_2_oxaliplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAPK family signaling cascades Reactome Pathways 2024 1.0 null TP53 ChEA Transcription Factor Targets 1.0 null BB49-HNC COSMIC Cell Line Gene Mutation Profiles 1.0 null NHLH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.0275 HUNS1 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56971 kinase binding GO Molecular Function Annotations 2025 1.0 null PWR-1E Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.74564 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.0017 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.8233 GSE174701_5_v_8_maml3_human RummaGEO Gene Perturbation Signatures 1.0 null Hypertension dbGAP Gene-Trait Associations 1.0 0.711358 Postsynapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 MATK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18006 hsa-miR-497 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null K562_ENMD-2076 L-Tartaric acid_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0174061 hsa-miR-195 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.123 Smooth endoplasmic reticulum cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.521 STOM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39513 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922453 abnormal body composition MPO Gene-Phenotype Associations 1.0 null Ezatiostat DeepCoverMOA Drug Mechanisms of Action 1.0 0.24 DEAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13732 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.836073 hsa-miR-548an TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 Nrd1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.591 PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.89477 JARID2-20064375-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7749-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE195786_0_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null NCIH2110 CCLE Cell Line Gene Mutation Profiles 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_2_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.45853 GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.05947 mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0601 Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02495 secretory granule lumen GO Cellular Component Annotations 2023 1.0 null STAT1-20625510-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZFP57-27257070-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Olig2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8346 GSE193351_4_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null glomerular GeneRIF Biological Term Annotations 1.0 null Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.991851 protein kinase binding GO Molecular Function Annotations 2025 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE159728,GSE159730_0_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-T6MN-0011-R1A-SM-32QOY GTEx Tissue Sample Gene Expression Profiles 1.0 1.34242 nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03278 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 0.92668 GTEX-S95S-1326-SM-2XCDK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.980051 WDR35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0939 CAL-72 COSMIC Cell Line Gene CNV Profiles 1.0 2.12225 GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26191 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07479 hsa-miR-516a-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26439 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17833 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26276 GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.23083 GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37311 abnormal spatial working memory MGI Mouse Phenotype Associations 2023 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF539 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06314 hsa-miR-539 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 TAK-733_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0134644 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17804 Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 47.1012 vincristine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.017591 RNF2-18974828-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.966931 SNU489 CCLE Cell Line Gene Expression Profiles -1.0 -1.8985 formation GeneRIF Biological Term Annotations 1.0 null PMC4686785__F8 PFOCR Pathway Figure Associations 2024 1.0 null K562_Trametinib_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0110944 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE67266_7_v_3_etoposide_mouse RummaGEO Drug Perturbation Signatures 1.0 null primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.90254 cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.51194 Diabetes DisGeNET Gene-Disease Associations 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.85124 ADCK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16115 Altretamine_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0173559 Adolescent Idiopathic Scoliosis DisGeNET Gene-Disease Associations 1.0 null GTEX-WRHU-0626-SM-3MJFI GTEx Tissue Sample Gene Expression Profiles 1.0 0.916933 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34669 QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847741 NCIH1693 CCLE Cell Line Gene CNV Profiles 1.0 1.56944 Avian pallium TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.627081 PRDM16-22522345-PALATE-MESENCHYMAL-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Assembly and cell surface presentation of NMDA receptors Reactome Pathways 2024 1.0 null SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles 1.0 1.43672 dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.03579 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15224 MHHNB11 CCLE Cell Line Gene Expression Profiles 1.0 1.5235 SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.37624 hsa-miR-1827 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 NCIH1618 CCLE Cell Line Gene Mutation Profiles 1.0 null SRPK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43257 Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9334 PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCIH2029 CCLE Cell Line Gene Expression Profiles 1.0 1.49945 SF1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_14625_KO_OGT_SRP146064 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.25724 Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22172 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27865 Hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.65 Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null asymmetric synapse GO Cellular Component Annotations 2023 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.052333 Chromosome 3q29 microdeletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.633 GTEX-XOTO-0326-SM-4B66K GTEx Tissue Sample Gene Expression Profiles 1.0 1.00648 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.298516 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles 1.0 0.908651 L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuron to neuron synapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Hypertension risk in short sleep duration GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.09086 significant GeneRIF Biological Term Annotations 1.0 null subunit GeneRIF Biological Term Annotations 1.0 null lung_4a HPA Tissue Sample Gene Expression Profiles -1.0 -1.22968 GSE127916_1_v_3_nras_human RummaGEO Gene Perturbation Signatures 1.0 null OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null nephrin GeneRIF Biological Term Annotations 1.0 null Human - Fetal Development - L1 - SATB2_LRRC7 positive cells HuBMAP Azimuth Cell Type Annotations 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.38524 LAN-6 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.332 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57323 r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11741 hyperactivity GWASdb SNP-Phenotype Associations 1.0 0.942765 K562_Bosutinib_10nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0137285 MTF2-20144788-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null KARPAS-422 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE102675_2_v_1_atf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE206870,GSE206872_1_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null EX229_CHP-212 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0145191 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22087 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5333-01A-01R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00482 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.001763 abnormal locomotor behavior MPO Gene-Phenotype Associations 1.0 null Perturb_11371_KD_METTL3_SRP292228 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.77037 GSE210580_4_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Dendritic spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.953 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-THRB_THRB Rummagene Transcription Factor Associations 2026 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210662_2_v_0_znf165_human RummaGEO Gene Perturbation Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null X-linked monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null anchoring junction COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE160765_2_v_1_twist1_human RummaGEO Gene Perturbation Signatures -1.0 null 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.49313 olaparib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0196518 ZC3H15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29764 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.43565 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46756 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.88879 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.56694 Daptomycin_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.0356241 cytoskeleton COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 MC116 COSMIC Cell Line Gene Mutation Profiles 1.0 null OSBPL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25116 PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.11592 head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03199 GSE95685_6_v_3_tcpobop_mouse RummaGEO Drug Perturbation Signatures -1.0 null Asymmetric synapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Perturb_11479_KO_Ring1_SRP321271 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.65434 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23039 TEN DepMap CRISPR Gene Dependency 1.0 4.08664 SNU899 CCLE Cell Line Gene Mutation Profiles 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02191 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.32385 receptor clustering GO Biological Process Annotations 2025 1.0 null hsa-miR-1253 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 postsynaptic density GO Cellular Component Annotations 2015 1.0 null hyperactivity MPO Gene-Phenotype Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain - Spinal cord (cervical c-1) GTEx Tissue Gene Expression Profiles 2023 1.0 1.21092 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75603 temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_9425_KD_H3F3A_SRP150639 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.56686 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles 1.0 1.16746 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 COGAR359 DepMap CRISPR Gene Dependency 1.0 2.58523 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.250953 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80088 L428 CCLE Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.15146 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null K562_Crizotinib_1然_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0150077 STAT3 ChEA Transcription Factor Targets 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50983 TP53-23651856-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.66152 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 1.092 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21675 RCC-JW COSMIC Cell Line Gene Mutation Profiles 1.0 null Omeprazole_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0287651 GSE126345_0_v_10_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null I-II Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34314 GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 2.08415 GSE219195_0_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null QIMR-WIL COSMIC Cell Line Gene Mutation Profiles 1.0 null Ipatasertib_SNU-423 Tahoe Therapeutics Tahoe 100M Perturbation Atlas 1.0 0.0338141 SNU1196 CCLE Cell Line Gene Expression Profiles -1.0 -2.35802 Perturb_11372_KD_METTL3_SRP292228 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.55169 GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01381 NR3C1-23031785-PC12-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 1.67572 detected GeneRIF Biological Term Annotations 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3896 GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20515 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0058 hypertension DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.464771 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69516 PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-875-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null lateral nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.836243 hsa-miR-548ab TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29778 dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20361 Elementary body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.696 hel HPA Cell Line Gene Expression Profiles 1.0 2.40722 PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_126_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.2647 Capsular epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.617 Syntrophin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.918 Distal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.067 attention deficit hyperactivity disorder GWASdb SNP-Phenotype Associations 1.0 0.942765 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.861082