association dataset threshold value standardized value ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15323 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.109566 layer 4 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41095 SNUC5 DepMap CRISPR Gene Dependency 1.0 7.76949 RNF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81902 SOX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27088 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.49314 Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 STK31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2712 CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.952835 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.78101 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20169 JAK2_activemutant_72_GSE21842 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.6479 GSDMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17401 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null RHPN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76349 HCC4006 CCLE Cell Line Gene CNV Profiles 1.0 1.50651 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05353 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.25282 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24976 RERE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1023 PRRC2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81937 PPM1J CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74689 NOCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07674 Perireunensis nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30605 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31843 TMSB4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88702 medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.976377 H2AFZ ENCODE Transcription Factor Targets 1.0 null KCNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91847 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.15581 ETNK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33914 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34252 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35185 NABP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05339 Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00506 ENOSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64729 HSPB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07905 LN-18 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22285 MYC ENCODE Transcription Factor Targets 1.0 null MARF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10855 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4373 dorsal septopreoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38013 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07771 ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7532 DNPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93831 SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.40362 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5121 2313287 CCLE Cell Line Gene Expression Profiles 1.0 1.45581 PPARA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38089 NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.29741 VMCUB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.37074 QKI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83771 Organism form TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00687 STAT3 ENCODE Transcription Factor Targets 1.0 null LHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96605 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.9306 Cortical plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02184 Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13344 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE206400_3_v_0_nusinersen_mouse RummaGEO Drug Perturbation Signatures -1.0 null Internal female genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.923101 PNPLA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9134 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3218 ZNF469 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31201 HNF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36517 RT11284 CCLE Cell Line Gene Expression Profiles 1.0 1.5187 PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825955 Perturb_17268_KO_Sox30_SRP139811 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.654 CD59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88499 Gustatory areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11384 MYEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94728 abnormality of immune serum protein physiology GWASdb SNP-Phenotype Associations 1.0 0.772313 PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5809 layer 3 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51613 H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100291_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.63211 DIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00667 ATP6V1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16424 Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08801 SKUT1 CCLE Cell Line Gene Expression Profiles 1.0 1.81632 periventricular stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27926 Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25902 NEUROD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4669 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30872 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07433 EED CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41254 reticular formation of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00327 TMEM98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24459 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.7179 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.57698 RHOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98692 TREX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90668 Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31922 diagonal part of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07196 superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21498 BHLHA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53005 AADAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33298 r4 part of parvocellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30007 MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4838 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27833 HT1376 CCLE Cell Line Gene CNV Profiles 1.0 2.68678 IL17C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13817 PMC8567280-EMBR-22-e53014-s008.xlsx-PC3_TIP5_bound_promoter-Unnamed_4_BAZ2A Rummagene Transcription Factor Associations 2026 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05353 MM160113 DepMap CRISPR Gene Dependency 1.0 3.1752 intermediate stratum of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53294 POLR2J2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14048 DES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26508 FAM83H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58091 CCDC88A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12735 intermediate stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12987 ZSCAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21747 NOL4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6795 supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05725 SEMA4F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88463 HNRNPCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63707 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4467 Katanin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.968 MTRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48474 Intraciliary transport particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.673 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.27022 SRSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1475 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49059 RAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58555 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 117.702 RAB4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60698 NKX2-4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14555 Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.298 ZNF222 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36253 H2BC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17102 TMEM106A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18725 NCK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85145 KYSE-150 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.913383 GALK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31622 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5632 ASCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03841 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6612 GOLGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56514 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89357 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.853717 DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30613 Alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CAKI1 CCLE Cell Line Gene Expression Profiles 1.0 1.71524 KCNJ11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24272 RSPRY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66068 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.62098 PNKP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59046 stomach HPA Tissue Protein Expression Profiles 1.0 1.15104 BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8368 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.22278 MAZ ENCODE Transcription Factor Targets 1.0 null EVX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16297 GFOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21385 periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91219 CEBPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07274 AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ZNF425 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99428 ZFYVE26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.452 ZNF84 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46727 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03301 YTHDF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69484 PABPC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.64871 ZNF524 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2396 layer 2 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20931 r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42207 ovary HPA Tissue Protein Expression Profiles -1.0 -1.91372 EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -7.82121 COL6A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34942 intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55022 Genital Diseases, Female CTD Gene-Disease Associations 1.0 1.19542 TE-4 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 RCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00088 KCTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93172 SMAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7312 mantle zone of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12554 CREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.351 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6589 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149903_3_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null RHBDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29851 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.278736 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45358 ZNF239 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73922 G3BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33874 CACUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4523 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38756 AIDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34547 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.5929 Orbital area, medial part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33065 PYGM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20974 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10809 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5243 MAFF ENCODE Transcription Factor Targets 1.0 null MLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60826 CCDC74A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67881 MYC-19079543-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null DFCI024 CCLE Cell Line Gene Expression Profiles -1.0 -1.64623 lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11414 mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11511 JK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.57372 lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13059 FOS ENCODE Transcription Factor Targets 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSS CCLE Cell Line Gene CNV Profiles 1.0 1.51462 PSME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07722 RNF114 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11493 PLEKHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92628 ASPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53386 Medial amygdalar nucleus, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01632 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5789 HSC4 CCLE Cell Line Gene CNV Profiles 1.0 1.47967 496100410_TCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.97976 RAJI CCLE Cell Line Gene Expression Profiles 1.0 2.64753 WM793B COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24165 YWHAQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1702 SPOUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38274 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30296 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 1.15104 APLP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04737 ELOVL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02999 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29568 BUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98354 HNRNPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29038 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33235 BNIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85981 ZNF841 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87216 p3 part of the ZL core Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35693 TWIST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.28853 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.968688 Ventral medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27322 endometrium HPA Tissue Protein Expression Profiles -1.0 -0.790636 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21788 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50566 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09003 FOS_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IGFBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39662 frontal operculum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.873623 ZNF488 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80461 SLC16A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51562 C1orf226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44164 mantle zone of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19087 SF767 CCLE Cell Line Gene CNV Profiles -1.0 -1.82196 GATA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34438 P31FUJ CCLE Cell Line Gene CNV Profiles -1.0 -1.91763 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24478 ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81512 IREB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10373 EDRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84817 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00589 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6316 NCIH650 DepMap CRISPR Gene Dependency 1.0 2.67054 Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.729 TBX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 RAP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69801 ventral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00514 PSMD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59942 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.14755 GPSM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47739 Posterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56584 496100399_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.47321 all GWASdb SNP-Phenotype Associations 1.0 0.030833 LACTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29081 ZSCAN4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3336 NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8938 UBA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75001 RPH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53027 GABPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17793 VPS39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98919 intermediate stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3649 cerebral cortex HPA Tissue Protein Expression Profiles -1.0 -0.790636 PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.91372 CRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12061 NCIH1838 CCLE Cell Line Gene CNV Profiles 1.0 2.20676 CR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62788 SSH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38294 496100492_TCx_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.7362 dorsal part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06598 TRNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1317 PIK3C2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89075 NR3C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.0462 496100396_HIP_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.42461 STOML2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67499 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null YIPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2497 r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05559 IM95 DepMap CRISPR Gene Dependency 1.0 2.34021 ZNF614 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 TTLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23845 AFDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46391 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0057 periventricular stratum of r3Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12649 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TPD52L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06997 midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.70558 r8 part of lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50018 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8063 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3471 mantle zone of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00699 EW8 CCLE Cell Line Gene Expression Profiles -1.0 -1.48822 ISOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06476 NLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83655 ventral tier of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19503 mantle zone of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21952 HT-1376 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.1493 NUGC4 CCLE Cell Line Gene CNV Profiles 1.0 1.53203 FBXO6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4544 SMAD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31057 Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23461 HYLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30153 lateral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09765 PRB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17076 dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.49987 NCIH1734 CCLE Cell Line Gene Expression Profiles -1.0 -1.56723 CLEC2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82294 ZNF513 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77853 HLA-E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57875 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null PC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1925 PDLIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83479 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5855 TE1 CCLE Cell Line Gene CNV Profiles 1.0 1.47774 STPG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29764 EWSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77336 LN235 CCLE Cell Line Gene Expression Profiles -1.0 -3.72378 ESRRG_Deficiency_GDS2811_638_mouse_Fetal heart - Homozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PRMT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94588 BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6753 Primary somatosensory area, nose, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03665 A-CA-04-2009(H1N1)_18Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.99829 NR4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77239 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.943717 TOMM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57429 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7411 intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07276 ZBTB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5501 ELF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11084 ZBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94666 lateral part of PcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06712 PKDCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03621 SND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65202 inferior frontal gyrus, orbital part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2439 ADNP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46339 MDST8 CCLE Cell Line Gene Expression Profiles 1.0 2.30364 CHML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37986 Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22952 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE125014_6_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.269 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.96516 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1882 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.895261 Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF722 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77897 SIDT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25938 paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45991 METRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8713 ZNF221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38987 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06024 NAA35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52684 ASCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21263 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84281 RNASE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33372 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3169 SLC35A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45594 ZNF90 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65849 cingulate gyrus, frontal part, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.857967 JHU011 DepMap CRISPR Gene Dependency 1.0 4.00005 Adrenal gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896678 SETX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53163 lung HPA Tissue Protein Expression Profiles -1.0 -1.20978 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NRN1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66505 PALM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17928 mantle zone of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06564 intermediate stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11384 Small intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.572823 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ventral juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12987 GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9179 THG1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.6565 GABRE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02719 EN CCLE Cell Line Gene CNV Profiles -1.0 -1.55297 PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1 Rummagene Transcription Factor Associations 2026 1.0 null OAZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55022 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41677 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01546 PGR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4132 FARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43595 NUDUL1 CCLE Cell Line Gene Expression Profiles 1.0 1.466 Primary somatosensory area, unassigned, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33649 TNFRSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41798 SLR25 CCLE Cell Line Gene Expression Profiles -1.0 -1.52778 T84 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3772 ANO9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43476 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.5789 YY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78275 salivary gland GTEx Tissue Gene Expression Profiles -1.0 -1.17391 H3C10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01377 MOSMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.86251 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41219 TMEM59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09076 XRCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40648 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4713 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.21402 CRYGD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59063 CDS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64375 DNALI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05625 ZNF683 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13062 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956101 TMEM263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88813 ROGDI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28944 YTHDF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65009 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77546 CCDC17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15518 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.3435 MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AP3M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44075 postcentral gyrus, left, superior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.872447 CCDC87 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6947 RBM18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60138 496100370_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.24511 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8408 NES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40166 NCIH1650 CCLE Cell Line Gene CNV Profiles 1.0 1.36086 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.573 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16243 parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02537 TMEM35B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86378 r3 part of parvicellular medial vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12617 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896678 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9222 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8238 Primary somatosensory area, trunk Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24731 OV56 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835622 SNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08996 H1-5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68552 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06263 TMUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98075 ZNF70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80549 CDYL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38166 TAF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6493 NUDT16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57288 LTN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19775 superficial stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12617 RNASE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37727 PER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39762 ETNK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84148 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9729 Primary somatosensory area, lower limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01632 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03317 H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1568 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 DHX40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22128 PDK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36015 Radial spoke head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.261 ZNF773 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38569 JHESOAD1 CCLE Cell Line Gene Expression Profiles -1.0 -1.62289 CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.924506 GDF15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33704 HOXB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5376 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34392 496100375_FWM_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.58671 CHTF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47092 ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.109369 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01448 SCC4 CCLE Cell Line Gene Expression Profiles -1.0 -1.57687 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM229A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63719 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.55147 METRNL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11368 EME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54334 KMH2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26602 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71113 POLR1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7009 lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.874325 mantle zone of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07196 APOBEC3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0602 GEM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39144 NCI-H1623 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 ALX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97056 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.968063 CA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9781 MBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88607 salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.16411 NCIH1355 CCLE Cell Line Gene Expression Profiles -1.0 -1.59806 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 GFPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44816 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24871 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09889 hESC Derived CD184+ Endoderm Cultured Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.956192 Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 CAMK2N2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96251 NCIH1355 DepMap CRISPR Gene Dependency 1.0 22.6351 RAB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92351 H2461 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15693 VKORC1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24792 ASRGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01882 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1249 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17835 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.059748 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.326 ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9031 PL18 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4695 mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55022 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32854 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12876 FN3K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64767 SSBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99245 STRN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57663 LYSMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90691 CENPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20034 JcP contribution to LTL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24892 ESYT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59523 DERL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0726 CMK115 DepMap CRISPR Gene Dependency 1.0 4.08815 LIN54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38715 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.23273 BICRAL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27205 OSR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13754 parvicellular (lateral) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14807 CAV3_KO_GDS3533_17_mouse_mammary glands GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ETAA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51151 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5666 ZNF611 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27981 SW1990 DepMap CRISPR Gene Dependency 1.0 4.42516 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21529 MOLT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.86644 LIN28A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60968 Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.94203 spleen HPA Tissue Protein Expression Profiles -1.0 -0.790636 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4892 ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.269 AAGAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78553 QDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49538 PRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45699 TEAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19585 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.980623 NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.977828 MFE280 DepMap CRISPR Gene Dependency 1.0 5.09346 CHAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44451 Walker-Warburg syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.239 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06653 Puberty, Precocious CTD Gene-Disease Associations 1.0 1.14678 CASP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86666 HAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52291 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10172 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71113 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BTRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44794 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.5855 CPXM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04797 496100666_HIP_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30206 FTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49873 RAB31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74313 EXOSC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78429 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896678 SLC46A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58285 POLDIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10398 P2RX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01295 PPP1R1A_KO_GDS1920_708_mouse_hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4505 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8101 ZC3H15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31022 TRIM27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6881 THAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6352 NCBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95517 TMEM69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57438 CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841413 TMEM237 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23442 CCNC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63023 Cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06335 SCAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18779 GSE87412,GSE92423_0_v_4_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1467 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99377 H2AC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90617 Digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4559 TNFRSF10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98354 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.866258 FKBP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73471 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.866258 pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04046 Primary somatosensory area, unassigned Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53659 SUPT7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65541 ODF2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15979 Stomach TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1673 intermediate stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19188 PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_156_TCF7_rep1_sorted_peak-Gene_Name_TCF7 Rummagene Transcription Factor Associations 2026 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.91 PTRH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19992 ATXN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0325 SETDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06791 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06382 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06653 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.642 GPX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5823 NAMPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38611 periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43073 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21746 496100587_FWM_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.31322 GALR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03765 ARRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57688 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932419 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869381 Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05489 COX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29694 CARNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79548 superficial stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51648 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.13096 small intestine HPA Tissue Protein Expression Profiles 1.0 1.15104 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.7575 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00327 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 FAM136A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19352 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80384 SFRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60063 superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02016 ANAPC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07755 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6808 ENTPD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.08156 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.689 HS683 CCLE Cell Line Gene Expression Profiles 1.0 1.61358 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.27869 RASSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04097 DEPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59472 EXOC3L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49826 MPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03693 layer 4 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39417 MIER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35569 KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68322 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84481 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCNA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0809 PSMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27159 NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30067 Loin TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.282 MRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67887 ADM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27698 OGFRL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61361 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21952 nucleus subcoeruleus, r1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36588 SYK_druginhibition_289_GSE43510 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.2352 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15323 CPHXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63257 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.91372 precommissural pretectal domain Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19503 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29096 TNFAIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40982 ANG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04961 NCOA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4769 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71283 LN215 CCLE Cell Line Gene Expression Profiles -1.0 -1.59736 UOK101 CCLE Cell Line Gene Expression Profiles -1.0 -2.41356 Localized scleroderma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.109 LRRC34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56517 SEPHS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54732 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null SOX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92922 496100287_TCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.022 STOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60371 GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null RUNX1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null IDE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82469 SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 F36P CCLE Cell Line Gene CNV Profiles -1.0 -1.42207 SNU761 CCLE Cell Line Gene CNV Profiles 1.0 1.83491 ZC3H12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26965 FAM89B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7983 SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.436 Sublaterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04612 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.790636 TIMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66638 pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66353 SLFN11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98406 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4718 MT-ND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7337 D283MED CCLE Cell Line Gene CNV Profiles -1.0 -1.9925 r8 (gustatory) part of solitary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27957 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16328 MRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34314 ZNF354A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.68654 GSE125014_1_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35149 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 RNF149 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5899 FAM170A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0026 NOL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52558 NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.807 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83764 Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03111 CAL-72 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15873 CAPAN1 DepMap CRISPR Gene Dependency 1.0 14.7015 COLO684 CCLE Cell Line Gene Expression Profiles 1.0 1.80909 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61496 H2AC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98913 SOX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33137 MOLM13 CCLE Cell Line Gene CNV Profiles 1.0 2.46765 ERMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06739 NCI-H2110 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 ZNF282 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64137 layer 2 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62894 SLR20 CCLE Cell Line Gene Expression Profiles -1.0 -2.19657 ATP5F1E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60978 GSE264621_1_v_3_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.024389 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.39217 Transient neonatal diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.251 EIF2AK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80688 MBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37547 layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05559 PLIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57754 Primary somatosensory area, unassigned, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15222 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.0969 SNU410 CCLE Cell Line Gene CNV Profiles 1.0 2.06862 Pancreas TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ABTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98082 Embryonic structure TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Mouth TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833941 SK-MES-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8125 GLDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74597 CORO1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32936 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.2109 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.866058 mantle zone of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59302 PLBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27447 HSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25904 inferior frontal gyrus, opercular part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.828175 SEM CCLE Cell Line Gene CNV Profiles -1.0 -1.52905 GNA11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86419 mantle zone of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06526 SNUPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90527 ALG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44918 NCI-H2066 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60234 intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24208 496100487_HIP_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.55058 GPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62208 NGFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63267 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.042768 MOLT3 CCLE Cell Line Gene CNV Profiles -1.0 -2.13177 CLCN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44025 XPO5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06451 TMEM151B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61916 GNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51573 TIG3TD CCLE Cell Line Gene Expression Profiles -1.0 -2.19711 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.477 GPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46736 TRAF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32787 TEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49707 Phosphopyruvate hydratase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.986 CDC42EP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38811 GSE264621_1_v_6_secretin_human RummaGEO Drug Perturbation Signatures 1.0 null CI1 CCLE Cell Line Gene Expression Profiles 1.0 1.65179 Primary somatosensory area, trunk, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53616 posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.48598 Large intestine TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null APOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24906 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28789 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927355 ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7763 CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47385 CTBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33791 THAP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73337 Xanthophore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.151 PAX2 JASPAR Predicted Transcription Factor Targets 1.0 null BOLA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98319 r7 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35074 PLS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8463 ZFY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93823 SDR42E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28626 PNMA6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48356 tegmental field of p3 (Forel's field) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53804 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09889 Outer dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.927 A1207 CCLE Cell Line Gene Expression Profiles -1.0 -2.0268 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31093 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.21692 ZNF154 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65156 CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.977828 HCT116 DepMap CRISPR Gene Dependency 1.0 5.2026 parietal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14609 SNU520 CCLE Cell Line Gene Expression Profiles 1.0 1.38543 JHUEM3 CCLE Cell Line Gene CNV Profiles -1.0 -1.45293 lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.20978 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.977092 LTB4R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75568 adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.15104 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4284 SPRING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79308 PAK1IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97385 BRD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.38577 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.866258 RBIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58344 mantle zone of VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16859 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17832 SSX2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97577 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8501 ZNF135 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.0369 STX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3396 ZNF428 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58254 SEC22C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14506 mantle zone of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35505 MIDEAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40408 Primary somatosensory area, lower limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47451 GSE133763_0_v_1_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null PACSIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15032 MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null GOLGA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67032 ATP8B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32327 UT7 CCLE Cell Line Gene Expression Profiles 1.0 1.66188 SPRED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90627 NCIH596 CCLE Cell Line Gene CNV Profiles 1.0 1.56344 breast HPA Tissue Protein Expression Profiles -1.0 -0.790636 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9361 intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24354 FAM118B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32706 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tentacle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.815 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null SNU1079 CCLE Cell Line Gene CNV Profiles 1.0 1.43791 TUBB4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69499 PDF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.46588 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7917 Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10607 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5047 Primary somatosensory area, lower limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7651 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15568 ANKZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63914 PHF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96225 AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 KCNC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67102 perimammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81405 MLH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72213 ERGIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75805 intermediate stratum of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59183 GSE193282_3_v_1_cd44_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.0564 SARM_KO_GDS4842_412_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.21421 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58986 MIS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57969 TE-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 NFRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44868 Melanophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.871 ZNF33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19421 PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.78646 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17581 CHID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55783 medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956536 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00832 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KCTD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69071 IGSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42328 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45314 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1876 intermediate part of the arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44365 r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02087 Lymph node TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6279 496100412_FWM_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.81236 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4742 CH157MN CCLE Cell Line Gene Expression Profiles -1.0 -2.28437 ZNF792 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67895 HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00506 mantle zone of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45732 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 SIVA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29925 ZDHHC20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94004 SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.977555 496100561_PCx_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19559 TMEM88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75684 CTSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67338 SET CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8673 HMGXB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70038 ZNF534 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77624 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2881 KASUMI2 CCLE Cell Line Gene CNV Profiles -1.0 -1.56088 periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89435 SW579 CCLE Cell Line Gene CNV Profiles 1.0 2.24044 mantle zone of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3963 superficial stratum of CoPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08038 TWSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50776 STPG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37937 ZNF320 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88534 UMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76695 CTCF ENCODE Transcription Factor Targets 1.0 null OSC-20 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75851 RAB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15397 IOMMLEE CCLE Cell Line Gene Expression Profiles -1.0 -2.0106 Placenta TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2638 RUNX1 ChEA Transcription Factor Targets 1.0 null KASUMI1 CCLE Cell Line Gene Expression Profiles 1.0 1.34852 MYC ChEA Transcription Factor Targets 1.0 null NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null PUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40058 intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28083 Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.895261 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.64461 RHOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88876 SLR21 CCLE Cell Line Gene Expression Profiles -1.0 -1.85768 ATF7IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03589 PDCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30067 H4 CCLE Cell Line Gene CNV Profiles 1.0 1.81656 superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23124 Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.709 BTBD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47552 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857928 C1orf116 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82576 PHOX2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02817 LPAR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12184 Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04234 NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77546 Primary somatosensory area, trunk, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26522 SNAPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55154 CARMIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05381 Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZNF521 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81436 PATL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67096 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.94809 HSC3 CCLE Cell Line Gene Expression Profiles 1.0 1.85069 STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9945 NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.8874 SPTAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8119 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.54493 periventricular stratum of r4Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15631 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48961 Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 PCBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19986 Primary somatosensory area, trunk, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77287 Primary ciliary dyskinesia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.332 TMEM82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73899 GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8169 TAGLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78441 RAB6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93003 DLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98905 ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null posteroventral part of alar p3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1626 SPI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12206 PPP1R17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30605 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825955 TAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5902 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.90032 UNCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03863 LRPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38537 C8orf76 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32861 RASD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65596 496100619_HIP_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.87316 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49354 duodenum HPA Tissue Protein Expression Profiles 1.0 1.15104 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927355 SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 LYL1 ChEA Transcription Factor Targets 1.0 null S100A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51074 GSE210388_2_v_0_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null NCIH69 CCLE Cell Line Gene Expression Profiles -1.0 -1.51853 MRPL40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19884 EID2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39032 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60313 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49059 medial orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.874669 superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24682 TRMT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2267 MESSA CCLE Cell Line Gene CNV Profiles -1.0 -1.74514 SH3BP5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08912 AP3S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87622 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04234 CGTHW1 CCLE Cell Line Gene CNV Profiles 1.0 1.57885 KMT2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96052 MPV17L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67019 NDRG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 74.4855 superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20517 H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCDC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14621 PDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77849 r4 liminal central gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15568 PITX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4551 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF263 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6273 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04756 POLR2A ENCODE Transcription Factor Targets 1.0 null C22orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7588 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 2.07083 schizophrenia GWASdb SNP-Disease Associations 1.0 0.668836 TP53INP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33464 GSE149903_0_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null RAPGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68867 superficial stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16034 DAZAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63255 HEKTE CCLE Cell Line Gene Expression Profiles -1.0 -1.47262 LYL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NCIH1373 CCLE Cell Line Gene Expression Profiles 1.0 1.68041 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2561 PITX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42503 TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8439 A204 CCLE Cell Line Gene CNV Profiles -1.0 -2.45031 PMC7825356-8844261.f3.docx-33-ZNF695_ZNF695 Rummagene Transcription Factor Associations 2026 1.0 null CAL72 DepMap CRISPR Gene Dependency 1.0 6.2817 Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05175 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.74742 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.956101 KIAA0930 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83791 periventricular stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2846 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.46153 ZNF764 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26413 paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.978979 PHGDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17531 GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00579 DSN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56553 LMO2 ChEA Transcription Factor Targets 1.0 null DIFI DepMap CRISPR Gene Dependency 1.0 4.45317 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26996 Gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08842 peduncular subparaventricular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12461 BJHTERT CCLE Cell Line Gene Expression Profiles -1.0 -1.58107 B4GALT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60826 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 FGF22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74288 r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31951 NEUROD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87815 ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.319 RABEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46545 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07847 brain GTEx Tissue Gene Expression Profiles 1.0 1.90569 ZNF345 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83371 HNF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92223 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55885 496100341_TCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.90749 IFI6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23465 GRHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63941 Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43945 NCIH929 CCLE Cell Line Gene CNV Profiles -1.0 -1.64408 mantle zone of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14609 ATG13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1162 YIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8695 Dopaminergic A13 group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69578 superficial stratum of PCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14807 MYLIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78605 TRMT9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78002 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7714 NRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66717 PBX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30541 CLN8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61648 Secondary motor area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68414 FZD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77944 H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C2orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9282 HEC151 CCLE Cell Line Gene Expression Profiles 1.0 1.43309 SUCLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65753 inferior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07344 KHDRBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41066 NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13659 eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSNK1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3295 UBE2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65976 BRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23497 SPIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33099 SETDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28233 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.77047 ventropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16859 SHISA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07408 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.919308 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47434 optic fiber layer of SC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12335 496100468_PCx_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 5.59027 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null L1236 DepMap CRISPR Gene Dependency 1.0 4.74965 Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.17235 shell of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4634 Skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 RAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43237 TMEM81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32751 ZNF462 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67115 ZNF211 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38419 TAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18317 ventral reuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03778 SETD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75208 lateral terminal nucleus of the accessory optic tract, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07847 PPARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7143 LEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43212 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927355 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.81767 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_MYC_19079543 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null bladder GTEx Tissue Gene Expression Profiles -1.0 -1.17391 KIAA0232 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.90482 CLTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63012 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null OTX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1446 IFIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31526 T3M10 CCLE Cell Line Gene Expression Profiles 1.0 1.71986 COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.843826 IFT22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90672 periventricular stratum of r4Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30038 PCK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00677 SNU245 CCLE Cell Line Gene Expression Profiles 1.0 2.13181 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.269 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.989182 Silver-Russell syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.183 ZBTB12 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6893 496100592_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02013 TMEM222 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56161 FBXO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20345 ABHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80006 BCL2L11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04321 dorsal motor nucleus of the vagus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.967486 AKT1_OE_GDS2308[_473_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SMPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93305 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45247 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateral part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3963 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-156-MEOX2_MEOX2 Rummagene Transcription Factor Associations 2026 1.0 null cingulate gyrus, frontal part, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.853443 FOXC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68254 496100330_PCx_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05689 Colon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.03088 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100643_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33477 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21746 U343 CCLE Cell Line Gene Expression Profiles -1.0 -1.8397 retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74406 RS411 CCLE Cell Line Gene CNV Profiles -1.0 -1.69781 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04974 SNU466 CCLE Cell Line Gene CNV Profiles 1.0 1.54496 STK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80056 Rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08679 MRPL46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56171 Secondary motor area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12592 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF787 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24547 ZNF532 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68862 ACSM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81546 JHH7 CCLE Cell Line Gene Expression Profiles 1.0 2.01205 MYOC_OE_GDS1640_269_mouse_retina GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07477 Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.767 ALS2CL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71627 OELE CCLE Cell Line Gene Expression Profiles -1.0 -1.71045 LMNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52991 Anxiety Disorders CTD Gene-Disease Associations 1.0 1.4449 496100566_FWM_no dementia_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0648 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41212 PFDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29278 SRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5487 ZNF556 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08784 DDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66356 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.85735 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83688 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9947 PECAPJ41CLONED2 CCLE Cell Line Gene Expression Profiles 1.0 3.34814 CHRDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24296 TUHR10TKB CCLE Cell Line Gene CNV Profiles 1.0 1.37485 Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00541 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94831 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59685 LN382 CCLE Cell Line Gene Expression Profiles -1.0 -1.90441 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.860128 GATAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97155 C2BBE1 CCLE Cell Line Gene Expression Profiles 1.0 1.37306 reuniens nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39853 TEX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40798 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6875 NET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93778 TMEM250 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5837 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24715 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.977555 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29672 DRAXIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67487 VARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70785 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02055 RNH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77208 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7504 PYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02779 HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27732 NADK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21889 Nucleus of reunions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48487 E2A MotifMap Predicted Transcription Factor Targets 1.0 null SH3BGRL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32959 TPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25222 bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91219 NCI-H2444 COSMIC Cell Line Gene CNV Profiles 1.0 2.25904 TOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56106 Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.14958 dorsal part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21952 SHISA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19031 C8orf33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53003 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.49314 r8 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08125 COQ4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86309 DRGX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42145 CAL27 CCLE Cell Line Gene CNV Profiles 1.0 1.41802 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.865744 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19085 FOXG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45586 SKIC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08281 ACP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06333 FAM135A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5834 PRPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82946 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6686 superior temporal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895146 medial basal reticular formation of m1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7396 periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26476 ZNF703 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34724 ZDHHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5661 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.45676 nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.15104 r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06465 DNMT3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04158 layer 1 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.448 SMIM30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71257 UXS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47327 Nucleus of the solitary tract, gelatinous part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46089 NPY5R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35807 COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15176 KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38756 GLIS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72783 SEC31B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25044 SLC35F5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29728 intermediate stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7396 NETO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82402 ZSCAN20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65085 ventral part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.45732 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.8368 ZNF610 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44176 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8652 Primary somatosensory area, unassigned, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27767 NRROS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64087 NLRX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29334 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAV3_KO_GDS3533_357_mouse_mammalian glands GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NR2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6048 MRTFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94999 Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HCC2814 CCLE Cell Line Gene Expression Profiles -1.0 -2.12737 LAPTM4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40728 Inner dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.987 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.849277 SLC25A37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79591 JVM3 CCLE Cell Line Gene CNV Profiles -1.0 -1.96432 WM115 CCLE Cell Line Gene CNV Profiles 1.0 1.3289 HS3ST3B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93463 PYGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71315 NCBP2AS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5464 Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.936 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subpallial amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31743 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46715 FOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1166 ETV2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7176 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.488 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29787 DMBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06609 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.269 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-605-ENSG00000106511_MEOX2 Rummagene Transcription Factor Associations 2026 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.02867 SALL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55568 nerve GTEx Tissue Gene Expression Profiles 1.0 0.888021 496100361_TCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.05086 CREB3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86677 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.41483 NEK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43562 RANGRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2551 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5652 FCHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15277 QPCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41321 Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.269 MYH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44772 zona incerta complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59263 LGALS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99239 CAVIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84269 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.22564 HAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40105 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10172 Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03483 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8188 ZNF716 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12536 KMRC20 CCLE Cell Line Gene CNV Profiles -1.0 -1.42151 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null vertical nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21592 ARHGEF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38866 ZNF398 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27101 MT-ATP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31003 GSE135705_5_v_3_corticosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null TSR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8845 disease of mental health GWASdb SNP-Disease Associations 1.0 0.046575 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.065432 ZNF691 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42096 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02055 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38464 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.104135 posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79762 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.17391 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.30432 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00579 GGH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91359 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.895261 RPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48372 basal part of terminal hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0181 STARD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63437 ULBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64885 SF767 CCLE Cell Line Gene Expression Profiles -1.0 -1.73803 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83872 STT3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85154 gallbladder HPA Tissue Protein Expression Profiles 1.0 1.15104 TGFBR3L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85664 ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5686 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.49298 LY6E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96431 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.40971 reticular formation of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.8318 PDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81637 CAMA1 CCLE Cell Line Gene Expression Profiles 1.0 1.35331 rostral zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59183 C1orf109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20626 TGIF2LY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75684 UMRC2 CCLE Cell Line Gene Expression Profiles -1.0 -2.24045 G-361 Klijn et al., Nat. 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