association dataset threshold value standardized value amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18697 CLIC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15534 HDAC2 ENCODE Transcription Factor Targets 1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.870519 periventricular stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02823 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-Unnamed_16_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null 8305C COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3679-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 ECC10 CCLE Cell Line Gene CNV Profiles -1.0 -1.50387 GSE174383_6_v_7_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_EOMES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3192 GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.01428 TMEM131L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65995 GSE168676_2_v_3_dach1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RERF-LC-FM COSMIC Cell Line Gene Mutation Profiles 1.0 null DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.9942 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.090607 LSM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16488 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-X8HC-0226-SM-4E3K1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K27me3_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CMK COSMIC Cell Line Gene Mutation Profiles 1.0 null PA-TU-8902 COSMIC Cell Line Gene Mutation Profiles 1.0 null SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parasubthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58864 GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CL-40 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38716 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE80098,GSE80366_0_v_5_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.98382 GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.969153 GSE158458_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-SJXC-0426-SM-2XCFH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null GSE165704_0_v_1_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T8EM-0426-SM-4DM7E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7587 MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217405_3_v_2_osimertinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.32422 GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE201217_3_v_1_usf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SBC-3 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.853189 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11516 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47296 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 LYRM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54222 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null alzheimer's disease GWASdb SNP-Disease Associations 1.0 0.580046 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 UTY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52202 medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72192 GSE114284_2_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50319 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06637 GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 EP300 ENCODE Transcription Factor Targets 1.0 null Plant ovule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.946 DMS53 CCLE Cell Line Gene CNV Profiles 1.0 1.41589 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25429 GTEX-WFG7-0926-SM-4LMK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961953 Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49063 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.930554 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20632 FLI1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell envelope Sec protein transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.644 GSE138841_0_v_1_trim6_human RummaGEO Gene Perturbation Signatures -1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24139 Leucine rich repeat 4 InterPro Predicted Protein Domain Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S18-Table_S18_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-002_4H_vs_DMSO_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6915 MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.7046 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.854902 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6528 MBOAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53895 RELA ENCODE Transcription Factor Targets 1.0 null heparin_homo sapiens_gpl570_gse12710 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.12443 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45209 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0221 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.884701 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PX3G-0426-SM-48U1C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.885241 COLO 678 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.06904 disease GWASdb SNP-Disease Associations 1.0 0.031567 Perturb_1767_KO_Asxl2_SRP124824 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.87323 GTEX-QDVJ-1426-SM-48U1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 WM115 DepMap CRISPR Gene Dependency 1.0 5.42641 GSE165548_2_v_13_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hippocampus (hippocampal formation)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.963951 GTEX-OIZH-0326-SM-2HMKC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null intermediate stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18452 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-UT-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE175571_3_v_2_acsl6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-Q734-0526-SM-2I3EH GTEx Tissue Sample Gene Expression Profiles 1.0 1.01309 posteroventral (inferior) parietal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.987815 JHU-011 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5512 GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4425 GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DorsalRootGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.35267 hippocampus (hippocampal formation)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831398 PACADD119 DepMap CRISPR Gene Dependency 1.0 3.83587 ISHIKAWAHERAKLIO02ER DepMap CRISPR Gene Dependency 1.0 2.8486 HCC2998 DepMap CRISPR Gene Dependency 1.0 8.84144 PARP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81268 GSE178714_3_v_0_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06382 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926036 GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50983 NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 1.35233 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.880649 GSE231648_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1393 CRO-AP2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE213228_1_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50919 THAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16296 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null ACHN CCLE Cell Line Gene CNV Profiles 1.0 1.80266 GSE158834_7_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE84148,GSE96938_0_v_2_nrros_mouse RummaGEO Gene Perturbation Signatures 1.0 null sublayer 6a of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22233 WDR33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06271 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0226-SM-3MJFV GTEx Tissue Sample Gene Expression Profiles 1.0 1.12818 MDAMB134VI CCLE Cell Line Gene CNV Profiles 1.0 1.60803 Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t47d HPA Cell Line Gene Expression Profiles 1.0 0.830932 GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85004 GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.25442 GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XK95-0426-SM-4AT4R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 0.828405 HGC-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01973 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.308993 H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SKLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.72426 GSE174383_4_v_7_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.93583 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 BL3936 (PPP5C) NURSA Protein Complexes 1.0 null MC-IXC COSMIC Cell Line Gene Mutation Profiles 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17592 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.73077 LOXIMVI COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXP1_01_88 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59703 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4838-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EIF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19318 EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3823 supragenual nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01408 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6387 GTEX-R45C-0926-SM-3GAD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN ChEA Transcription Factor Targets 2022 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01311 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null RPS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99226 NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4425 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE235066_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22833 GTEX-XUYS-0005-SM-47JZ2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WYJK-1426-SM-3NM8V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07619 MYBL2-22936984-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null FOXRED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42383 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961953 GSE123958,GSE123959_0_v_1_mta1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15112 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09834 HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.562404 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SKNFI CCLE Cell Line Gene CNV Profiles 1.0 1.34194 GTEX-OXRK-0526-SM-3NB2F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.96227 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.65126 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1835 Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-X88G-0426-SM-47JZ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 cytoskeleton GO Cellular Component Annotations 2025 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17944 BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0683 paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44936 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.40626 GSE101336_1_v_2_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NUBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00056 GTEX-WH7G-1626-SM-4LVMY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4528 RABGGTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65945 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r9 part of nucleus gracilis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06936 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE158458_2_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FLCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02699 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.44163 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10574 NCI-H1299 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCTD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09621 GTEX-POYW-1126-SM-48TCI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nb4 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 UPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30643 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE224294_4_v_2_ngly1_human RummaGEO Gene Perturbation Signatures 1.0 null mRNA_ZFAND3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9692 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.034763 Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.059164 RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null 496100338_HIP_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.31652 H3K9me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.07247 GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 0.983141 GTEX-S4Z8-1726-SM-3K2AX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SF295 COSMIC Cell Line Gene Mutation Profiles 1.0 null FARP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40655 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.82394 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.77793 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 114.822 GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CBP-20019798-JUKART-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.24127 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28112 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94673 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAL-120 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.93487 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MRPL37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01824 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1582 GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OXRN-0126-SM-48TDM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0726-SM-4BOOP GTEx Tissue Sample Gene Expression Profiles 1.0 0.904817 Lhx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.6498 GTEX-R55E-0826-SM-2TC5M GTEx Tissue Sample Gene Expression Profiles 1.0 1.13538 ACHN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887034 GTEX-T2IS-0426-SM-32QPE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null CIB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1548 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16602 GTEX-QEL4-0326-SM-3GAE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JVM3 CCLE Cell Line Gene CNV Profiles 1.0 1.50166 POMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43479 GTEX-O5YT-0226-SM-32PK5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWOO-1326-SM-48TCJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 medial mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36413 Ciliated cell_Lung_Mouse CellMarker Gene-Cell Type Associations 1.0 null rostral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29683 GSTZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22583 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-1926-SM-32PL9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC5989213-41467_2018_4462_MOESM9_ESM.xlsx-4-Supplementary_Data_4_Genes_differentially_expressed_in_SETBP1-G870S_vs_Empty_293_FLP-In_lines_whose_promoter_is_occupied_by_SETBP1-G870S_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6576 BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5063 GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.17451 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-O5YT-1626-SM-32PK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44155 Preeclampsia_Placenta_GSE4707 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.65962 Sarcoma_SARC_TCGA-DX-A23Z-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE246461,GSE246463_5_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null Thyroid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.961889 GSE188870,GSE188871_4_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01673 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-299 COSMIC Cell Line Gene Mutation Profiles 1.0 null TONSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93496 DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE151612_4_v_11_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE184087_2_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Human - Fetal Development - L2 - Lung-Ciliated epithelial cells HuBMAP Azimuth Cell Type Annotations 1.0 null OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15256 GTEX-N7MT-0011-R4a-SM-2I3G9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01165 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.9336 GATA2-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-OHPK-1826-SM-2YUMR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-P4QR-1026-SM-2I5GP GTEx Tissue Sample Gene Expression Profiles 1.0 0.864901 NME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06059 GSE189683_1_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2432 H1-3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80867 superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39656 GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.11268 YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02419 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8035 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.42641 GSE128634,GSE128636_4_v_5_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE135350_3_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0215 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00105 C2CD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42816 GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869185 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.66466 LB771HNC DepMap CRISPR Gene Dependency 1.0 2.14426 SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.39976 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE114284_4_v_3_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of VPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09077 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.95436 GSE218060_7_v_0_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33968 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE154074_5_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null LSG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25088 SCC-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-QDVN-2326-SM-2S1PF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36785 layer 2 of PrS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23874 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.51825 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0863 hmc1 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Mitotic arrest phase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null LEPROTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95306 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69566 bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12837 Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02393 MAPK1IP1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35178 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.959 GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.67131 bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.717203 GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.66604 Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36457 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE63048_11_v_12_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SIN3A_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null Spinal cord TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60926 POLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14579 primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36319 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.73226 Perturb_399_KO_NFE2L1_SRP333364 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.57155 cerebellar cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05015 GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TMK-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82183 GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51461 HPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32729 KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918156 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.2004 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE174383_4_v_0_ly6d_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28731 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC6879454-Data_Sheet_1.xlsx-AA_disease-Unnamed_4_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5826 SJSA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null BCLAF1_01_214 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.87549 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.22647 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45514 H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE244518,GSE244520_1_v_0_dnmt3b_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPATA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26965 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918156 GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ITGA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77866 GSE220629_0_v_1_foxp3_human RummaGEO Gene Perturbation Signatures 1.0 null BHY CCLE Cell Line Gene CNV Profiles 1.0 2.06266 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Testicular somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.619 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null upper basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52155 GTEX-WYVS-0526-SM-3NM9W GTEx Tissue Sample Gene Expression Profiles 1.0 1.33385 NFYB ENCODE Transcription Factor Targets 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.947056 OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.864535 ZNF384_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Presubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25762 hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.886799 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.831508 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15600_KO_Twnk_SRP319510 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.43 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19999 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 0.93563 GSE224096_2_v_0_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_6250_KO_Ago2_SRP041835 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 PC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28468 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12051 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.908703 HAPSTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01482 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 1.01964 BHLHE23 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4957 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 6b of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22897 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE114553_0_v_1_lhx6_human RummaGEO Gene Perturbation Signatures 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.0081 GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles 1.0 0.856659 Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null III Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05771 GTF2F1 ENCODE Transcription Factor Targets 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 0.867825 blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.853486 GSE261563_9_v_4_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840954 GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40509 GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 0.941922 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-1026-SM-3GAF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE157960_2_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null NCAPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42911 496100671_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56053 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE154074_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null GTEX-RTLS-1326-SM-46MUN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22435 Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ciliated epithelial cell_Esophagus_Human CellMarker Gene-Cell Type Associations 1.0 null layer 5 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52738 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52029 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5WG-1726-SM-4LMI5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164463_0_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures -1.0 null TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.9418 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.916677 Subiculum, ventral part, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06459 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.62802 nasopharynx HPA Tissue Protein Expression Profiles 1.0 1.18262 TMA16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31861 STAT3 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.587 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DG-75 COSMIC Cell Line Gene Mutation Profiles 1.0 null BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8513 GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KYAE1 DepMap CRISPR Gene Dependency 1.0 3.6624 blood GTEx Tissue Gene Expression Profiles -1.0 -1.30378 retromammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55779 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.1436 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rislenemdaz DeepCoverMOA Drug Mechanisms of Action 1.0 0.2 Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRNP200 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24322 KYAE-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null UBTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56692 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8787 seminal vesicle HPA Tissue Protein Expression Profiles 1.0 1.18262 GSE158834_7_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76285 PTGR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05263 Shelterin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.893 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.96947 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12809 Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 1.26775 COG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63687 RPS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16154 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.013 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4328 NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1833 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9811 GTEX-PLZ4-1226-SM-2I5FE GTEx Tissue Sample Gene Expression Profiles 1.0 1.05715 ACBD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77326 Perturb_4457_OE_Atg7_SRP310882 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.69866 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HNRNPUL1_02_109 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.16993 cell part LOCATE Predicted Protein Localization Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEx Ovary 20-29 vs 60-69 GTEx Tissue-Specific Aging Signatures 1.0 8.93407 layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10115 GSE166783_0_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF451 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55814 Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38006 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.94002 RPMI-6666 COSMIC Cell Line Gene Mutation Profiles 1.0 null TMEM221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26435 TGIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11956 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935732 PANC-04-03 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11625982-AJH-100-10-s001.pdf-94-MYC_MYC Rummagene Transcription Factor Associations 2026 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.11244 NCI-H378 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WFON-0001-SM-3P61W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17972 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null MPHOSPH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11138 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RU72-0126-SM-2TF6Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.01175 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.92218 MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6355 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.30883 LIN7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03299 KLM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28877 GTEX-QCQG-1826-SM-2S1P2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.24475 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01562 GSE135350_2_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33351 VIIAf Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15122 DOCK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77351 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.97211 Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5 HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null MYD88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66852 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53 Rummagene Transcription Factor Associations 2026 1.0 null amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25855 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.68385 SEZ6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19089 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.0011 PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1 Rummagene Transcription Factor Associations 2026 1.0 null GSE217405_3_v_2_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.252356 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.935 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918156 GTEX-PX3G-0826-SM-48TZS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 0.999678 GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles 1.0 0.826893 Endosperm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951 midbrain raphe nuclei Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18943 Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PX3G-2626-SM-2I3EG GTEx Tissue Sample Gene Expression Profiles 1.0 0.927655 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-0526-SM-2HMKV GTEx Tissue Sample Gene Expression Profiles 1.0 0.926714 BRF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23497 GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 WRNIP1 ENCODE Transcription Factor Targets 1.0 null MGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14485 GSE231648_4_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6416 hypoparathyroidism-retardation-dysmorphism syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5766 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.954883 FOXN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.4589 Subiculum, ventral part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36969 GTEX-Q2AG-0226-SM-2S1P4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12051 superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30673 BCPAP COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TMMY-1026-SM-4DXTI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5602 Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67969 GSE178714_6_v_7_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.22504 Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36969 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.01481 PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8249 RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48762 GSE217552_3_v_0_fisetin_human RummaGEO Drug Perturbation Signatures 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5919 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.5106 GSE178714_3_v_7_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null 496100645_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.31064 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1604 HNF1A_01_02 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.72312 GSE145249_0_v_2_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null GCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15652 Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ONECUT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.4632 Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36837 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1766 KP-N-YS COSMIC Cell Line Gene Mutation Profiles 1.0 null RIOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78931 GSE184087_2_v_3_tert_human RummaGEO Gene Perturbation Signatures -1.0 null 496100337_HIP_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24201 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5803 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.30187 GTEX-WOFL-0626-SM-3MJG3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Gall bladder cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.524 GSE101336_1_v_3_decitabine_mouse RummaGEO Drug Perturbation Signatures 1.0 null EME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06658 SK-N-BE(2) cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.546 HUP-T3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38913 SNRPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68044 Primary somatosensory area, mouth, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01318 PHF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01743 POU2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9206 TFCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99549 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.79425 GTEX-PLZ4-1326-SM-2S1O7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CAKI-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 GTEX-VJYA-1326-SM-3GIJC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PPM1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22435 GSE150669_2_v_3_roxadustat_mouse RummaGEO Drug Perturbation Signatures 1.0 null RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 0.922338 GTEX-SN8G-0526-SM-32PLE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE213228_4_v_3_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0383 TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.09479 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04109 H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_4344_KO_Tln1_SRP378238 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.73055 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874116 TIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79668 GTEX-UPK5-0126-SM-3GADM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RVPU-2326-SM-2TF6R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Peritubular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 Human - Fetal Development - L1 - Ciliated epithelial cells HuBMAP Azimuth Cell Type Annotations 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ZNF35 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1191 A704 CCLE Cell Line Gene CNV Profiles 1.0 1.45866 RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.9316 Megasporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.947 CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06593 PMC5624885-41537_2017_33_MOESM1_ESM.xlsx-SIT1-SIT1_Top_500_differentially_expressed_genes_with_perturbations_in_CNTNAP2_carrier_NGN2-neurons_using_DESeq2_NEUROG2 Rummagene Transcription Factor Associations 2026 1.0 null H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42237 Atf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.6401 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.859737 NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCIMY7 CCLE Cell Line Gene CNV Profiles -1.0 -1.47974 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WWYW-0926-SM-3NB2Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.47892 FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0726-SM-4AT64 GTEx Tissue Sample Gene Expression Profiles 1.0 0.982163 PJA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0961 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KM-H2 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5385 RERF-GC-1B COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-P44H-1026-SM-3NM96 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-0426-SM-2I3EP GTEx Tissue Sample Gene Expression Profiles 1.0 0.907832 tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09469 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.664 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.56336 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00654 GTEX-X4XY-0526-SM-46MW1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.3082 hippocampus (hippocampal formation)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.859261 GTEX-XAJ8-0326-SM-47JYI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PA-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hepatic Cirrhosis_Liver_GSE6764 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.69325 inner SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20221 FARAGE COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.65555 GSE131649_2_v_8_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null umbilicalcord BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.91634 GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10708 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOGGCCM CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 LB373-MEL-D COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.75239 BDCA4+_DentriticCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33951 primary auditory cortex (core)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.987815 ABHD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16737 GTEX-X3Y1-0226-SM-3P5Z5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1123 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64478 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952038 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE250534_0_v_3_cabergoline_mouse RummaGEO Drug Perturbation Signatures 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles 1.0 0.923103 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.20026 adrenal gland HPA Tissue Protein Expression Profiles 1.0 1.18262 Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM2B-26808549-CHIP-SEQ-REH-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30673 GSE210870_0_v_2_snai1_human RummaGEO Gene Perturbation Signatures 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8997 GSE167886_3_v_1_chd7_mouse RummaGEO Gene Perturbation Signatures 1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9422 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99672 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7924 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37679 Perturb_11517_KD_L1CAM_SRP076162 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.80384 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69209 XPO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72455 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null SNUPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90527 CSNK1G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47177 GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.0848 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.41895 GTEX-WYVS-0326-SM-3NM9V GTEx Tissue Sample Gene Expression Profiles 1.0 0.875268 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.933647 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119978,GSE180930_6_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null VIIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.860985 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SARS-CoV MA15_Day4-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.78937 A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.84187 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE128634,GSE128636_2_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null ZWILCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61297 Colorectaladenocarcinoma BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.834921 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32376 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE166783_4_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null caco2 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 medial superior olive Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.96947 Epididymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100372_HIP_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.98193 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78711 cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09538 CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Entorhinal area, medial part, dorsal zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10982 GTEX-UPIC-0926-SM-4IHLV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 APLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55234 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06259 GTEX-R53T-0526-SM-3GADL GTEx Tissue Sample Gene Expression Profiles 1.0 0.906786 ADAMTS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.25943 PMC10300023-41598_2023_37266_MOESM1_ESM.pdf-5-ZNF398_ZNF398 Rummagene Transcription Factor Associations 2026 1.0 null POU3F2 ChEA Transcription Factor Targets 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null GTEX-V1D1-2626-SM-4JBJH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWCY-1026-SM-48TD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE128333_4_v_5_tcf4_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.80512 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QV31-1626-SM-2S1QC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EN DepMap CRISPR Gene Dependency 1.0 2.17877 lateral part of MM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22885 A549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE235066_7_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QEL4-1226-SM-447A4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null GSE118816_2_v_3_myo1c_human RummaGEO Gene Perturbation Signatures -1.0 null GSE96649_1_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 1.18262 SF126 DepMap CRISPR Gene Dependency 1.0 2.7753 Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41043 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.96088 QIMR-WIL COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE193258,GSE193259_9_v_14_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null 8MGBA DepMap CRISPR Gene Dependency 1.0 2.08796 GTEX-WFON-1426-SM-4LVMT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FMNL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54095 Gametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.907 TCF12 ENCODE Transcription Factor Targets 1.0 null GTEX-WWYW-0426-SM-3NB31 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HUP-T4 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null spleen HPA Tissue Protein Expression Profiles -1.0 -2.53834 RBM14_02_03 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.70044 PMC4595011-pgen.1005555.s002.xlsx-MITF_UP_in_30kb-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null C15orf40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22877 Spinocerebellar ataxia type 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.386 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.85192 TAF1 ENCODE Transcription Factor Targets 1.0 null TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.22678 PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1 Rummagene Transcription Factor Associations 2026 1.0 null SPART CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83711 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11878 Cortical subplate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23652 GSE120200,GSE127269_1_v_2_asxl1_human RummaGEO Gene Perturbation Signatures -1.0 null NCI-H740 COSMIC Cell Line Gene Mutation Profiles 1.0 null ATXN7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29678 GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MDA-MB-453 COSMIC Cell Line Gene Mutation Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null RELA-24523406-FIBROSARCOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17538 GSE134029_3_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null A4-FUK COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38593 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1586 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 0.903784 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS ChEA Transcription Factor Targets 2022 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GF-A3OT-06A-23R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ankylosing Spondylitides_macrophage_GSE11886 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.48481 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5009-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.922 lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99745 GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6667 Hoxa11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.2668 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null PTDSS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9319 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0179 Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44021 C3orf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.50653 GTEX-RU72-1226-SM-2TF6N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 496100529_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.77479 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4107 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13814 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10496 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.52417 GSE120612_4_v_1_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RELA ChEA Transcription Factor Targets 1.0 null SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.11313 PLPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10668 GTEX-WH7G-0726-SM-3NMBM GTEx Tissue Sample Gene Expression Profiles 1.0 0.86493 HOXD9_01_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.96439 EBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QDVN-1226-SM-48TZ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OIZH-2026-SM-3NB1M GTEx Tissue Sample Gene Expression Profiles 1.0 0.880239 DCLRE1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43851 GSE216273,GSE216292_0_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35882 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.96762 LNZ308 CCLE Cell Line Gene CNV Profiles -1.0 -1.34974 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.20167 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.7607 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2582 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.868625 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QEL4-0726-SM-3GIJ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04664 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35961 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28443 H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null QGP-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QV44-2226-SM-447A3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 A253 COSMIC Cell Line Gene Mutation Profiles 1.0 null amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.955975 GTEX-NFK9-1726-SM-3TW8P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PCK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02882 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AQP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.50822 GSE226408_1_v_0_inpp4b_human RummaGEO Gene Perturbation Signatures -1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.49222 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.44063 MCEE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41933 POLR2A ENCODE Transcription Factor Targets 1.0 null PTER CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09675 ARID3A JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-OXRO-1726-SM-3LK6C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.41366 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.829 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-2026-SM-3GAEP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SLC8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04415 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALDH5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47585 H3K9me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.06409 paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.96078 EW-24 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-U3ZN-0626-SM-3DB7U GTEx Tissue Sample Gene Expression Profiles 1.0 1.28806 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.981097 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.865926 GTEX-UJHI-1226-SM-4IHLR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung_3e HPA Tissue Sample Gene Expression Profiles 1.0 0.897082 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43901 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.34398 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48284 GTEX-X4EP-0126-SM-3P5YV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KCNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01057 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4733 FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4249 mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71195 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24747 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39578 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12561 GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NEUROG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.888 nervous system disease GWASdb SNP-Disease Associations 1.0 0.048105 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.88281 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2485 DNASE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70778 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE174701_5_v_8_maml3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE153189_2_v_0_stat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XMK1-0626-SM-4B65A GTEx Tissue Sample Gene Expression Profiles 1.0 0.89275 GTEX-XAJ8-1426-SM-47JYM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14566 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MARCHF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58135 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mRNA_TCEA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22389 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10461 Perturb_6640_KD_ZBP1_SRP298473 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.65356 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46918 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.29704 GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hsa-miR-3145-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0383 primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1672 temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41303 T47D COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RPMI-7951 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1478 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.9988 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.64415 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50333 GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 0.947531 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-2326-SM-2HMLD GTEx Tissue Sample Gene Expression Profiles 1.0 1.26928 Sarcoma_SARC_TCGA-DX-A3LT-01A-12R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null GTEX-WFON-0526-SM-4LVLY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null QSOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.29617 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null retromammillary area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15825 PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 GSE159893_2_v_0_genistein_human RummaGEO Drug Perturbation Signatures 1.0 null Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29369 WDR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76009 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.918156 MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.11 SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null SUP-M2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Terminal bronchiole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.903 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Epididymosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.823 GSE180185_7_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-RUSQ-0626-SM-2TF5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.01961 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.47133 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE180813,GSE180815_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null L-428 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DYNC1LI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8316 H3K9me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.021 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-TMMY-0926-SM-33HBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.895547 NCI-H720 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35437 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null VCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5716 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34563 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2236 RAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25039 HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.13732 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.5478 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.36948 GTEX-PWOO-0726-SM-2I3EB GTEx Tissue Sample Gene Expression Profiles 1.0 0.828385 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77048 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66903 GTEX-QEL4-1526-SM-447AB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66063 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-0326-SM-3DB86 GTEx Tissue Sample Gene Expression Profiles 1.0 0.84777 RHBDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10312 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.026196 JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57132 GTEX-VJYA-0226-SM-4KL1Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LOU-NH91 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE164463_2_v_1_pax6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNRNP48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07268 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE118794_5_v_1_zmynd8_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03058 GSE155800_1_v_0_imatinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6 Rummagene Transcription Factor Associations 2026 1.0 null pineal_night BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.879892 Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.4387 H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OLIG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5592 TAF5L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89064 IZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920915 SUDHL5 DepMap CRISPR Gene Dependency 1.0 4.12871 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886339 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.2312 GSE162276_4_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null ACHN COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE188870,GSE188871_0_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43P-01A-31R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17286 SALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7428 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135350_2_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null NR2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04318 ZNF384 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles 1.0 0.973411 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3325 Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4361 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875064 GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15256 CLN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.62383 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3106 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01001 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NFK9-0326-SM-3MJGV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SNMC-1526-SM-2XCFN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.913009 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsal part of CoP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13713 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 150.531 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8494 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CAKI2 DepMap CRISPR Gene Dependency 1.0 3.724 GSE205163,GSE205164_5_v_8_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null Podocyte foot COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.06 GSE99687_3_v_1_smad5_human RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7421-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07223 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03379 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ANKRD50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2119 POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.773 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.89281 NTPCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07919 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN-27471255-CHONDROCYTES-MOUSE-RIB ChEA Transcription Factor Targets 2022 1.0 null GTEX-S341-2026-SM-2XCAA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MKRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21141 anterodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.927934 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12725 B3GAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4791 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_11_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null bronchus HPA Tissue Protein Expression Profiles 1.0 1.18262 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67124 GSE172146_2_v_0_mettl1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.6513 KCTD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23634 GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ONECUT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2944 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.6552 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.12103 MZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.966788 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10834420-12276_2023_1140_MOESM2_ESM.xls-ST12-Unnamed_5_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE80182_2_v_1_prmt5_human RummaGEO Gene Perturbation Signatures -1.0 null WSU-NHL COSMIC Cell Line Gene Mutation Profiles 1.0 null SAFB2_02_102 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.0 NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44816 HPAFII CCLE Cell Line Gene CNV Profiles 1.0 1.80297 GPATCH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.32921 LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1552 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21505 Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07581 GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.1225 GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Trachea-ciliated cell Tabula Sapiens Gene-Cell Associations 1.0 5.47384 PATZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13161 superficial stratum of ERCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23543 fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.78218 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26164 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null DMRTC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4513 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.068 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null A-VN-1203-2004(H5N1)_Day2-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.62447 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.19874 Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nasopharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35555 GTEX-T5JW-1726-SM-3GADN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HNRNPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06814 E2F4 ENCODE Transcription Factor Targets 1.0 null GSE251992_1_v_0_saracatinib_human RummaGEO Drug Perturbation Signatures 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.54282 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.13594 GTEX-P4QT-0226-SM-3LK68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26773 GSE160817_5_v_6_slamf6_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 WIL2-NS COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RTLS-0226-SM-2TF5E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4827 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3229 KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.989254 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2992 GTEX-VUSG-2826-SM-4KKZM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TMEM47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1318 GTEX-XUW1-0005-SM-4BOQ7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ATXN7L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27051 KYO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59739 GTEX-SNOS-0626-SM-4DM5F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ERF::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1203 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.2171 Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48902 lower basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92906 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GNG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82433 superficial stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26479 SP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.939048 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-1826-SM-2YUNF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.239452 NFIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52746 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.15269 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81236 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85618 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2582 Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33448 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.831499 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52071 YY1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MELK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56256 Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89475 Dlx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.2063 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.992701 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18046 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.911947 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920062 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893356 Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70503 496100597_HIP_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.41867 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.858858 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.70388 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.946068 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null MM160113 DepMap CRISPR Gene Dependency 1.0 4.64262 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8762 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.396 Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 110.656 GTEX-TKQ2-0826-SM-33HB6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Agranular insular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46272 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944334 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5987-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OTUD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90447 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.887034 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.02079 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SKMEL28 CCLE Cell Line Gene CNV Profiles -1.0 -1.65332 GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3846 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04621 MXI1 ENCODE Transcription Factor Targets 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.983316 CACUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02194 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00713 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2515 PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S4Z8-2026-SM-3K2A9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.24083 SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.88128 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3145 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KDM5B ENCODE Transcription Factor Targets 1.0 null LMBRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78262 Placenta TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56021 GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 schizophrenia GWASdb SNP-Disease Associations 1.0 0.82192 GTEX-XYKS-0926-SM-4BRVG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12051 H3K9ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 1.13927 EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893356 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12581 GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null bed nucleus of the external capsule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09077 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28443 hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.96032 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.827467 HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34454 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.11561 GTEX-XUZC-2026-SM-4BRW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6446 GIMEN DepMap CRISPR Gene Dependency 1.0 4.35822 GTEX-XUJ4-1726-SM-4BONW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 EEF1AKMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39814 Persistent Mullerian duct syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.003 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08296 EMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22636 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2126-SM-3LK7O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TIMM29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48042 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.15 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.09519 VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6184 GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1752 GTEX-S7SE-0926-SM-2XCD6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2892 NFYB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ5-1126-SM-3P613 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 G292CLONEA141B1 DepMap CRISPR Gene Dependency 1.0 7.47679 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65234 GTEX-XAJ8-0126-SM-47JYG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-P4QS-2626-SM-2I3EV GTEx Tissue Sample Gene Expression Profiles 1.0 0.956529 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0351 GSE203362_0_v_1_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null REST ENCODE Transcription Factor Targets 1.0 null Mammary gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-S33H-2426-SM-2XCB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXA1 ENCODE Transcription Factor Targets 1.0 null KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98163 schizophrenia GWASdb SNP-Phenotype Associations 1.0 0.717203 PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP Rummagene Transcription Factor Associations 2026 1.0 null MCFD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23543 EZH2 ENCODE Transcription Factor Targets 1.0 null GSE114284_1_v_5_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NPJ8-0011-R8a-SM-2HMLG GTEx Tissue Sample Gene Expression Profiles 1.0 1.34423 HUH-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.4425 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAB38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64299 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54278 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 tonsil HPA Tissue Protein Expression Profiles -1.0 -1.30116 SIN3A-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.08746 HMV-II COSMIC Cell Line Gene Mutation Profiles 1.0 null SHP77 DepMap CRISPR Gene Dependency 1.0 6.41539 CLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05811 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57921 EP300_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.964169 medial intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910906 SRC_overexpression_276_GSE37428 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.59943 HT-115 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVJO-0526-SM-447CE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 IGR37 CCLE Cell Line Gene CNV Profiles -1.0 -1.32359 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06082 APPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55732 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.04692 NCI-H1373 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16125 SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.258 NCI-H1734 COSMIC Cell Line Gene Mutation Profiles 1.0 null ATG2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31412 orbital frontal cortex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44019 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.868911 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20632 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5933 GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA3 JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 0.937479 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36319 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE198683_1_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48591 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0405 GTEX-QMRM-0826-SM-3NB33 GTEx Tissue Sample Gene Expression Profiles 1.0 0.95857 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE152734,GSE152735_2_v_0_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null MRPS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53388 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 0.82823 substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85779 retromammillary area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25184 RNF214 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63285 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.883319 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 81.1056 GSE165274_1_v_2_poldip2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NFYA ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYBL2-22936984-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XXEK-0826-SM-4BRWG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DAGLA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64452 GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ZNF610 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44176 GTEX-T5JC-0326-SM-4DM5C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.0564 GTEX-RM2N-0526-SM-2TF4N GTEx Tissue Sample Gene Expression Profiles 1.0 1.00598 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95201 breast HPA Tissue Protein Expression Profiles -1.0 -0.81701 GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4479 GSE138019_1_v_5_nudt12_mouse RummaGEO Gene Perturbation Signatures -1.0 null STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE138019_3_v_6_nudt12_mouse RummaGEO Gene Perturbation Signatures 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829146 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.901 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P78B-0826-SM-3NMCA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.597 GTEX-SSA3-0002-SM-3P61R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TULP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51777 GTEX-RM2N-0826-SM-48FD3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.68996 H3K27me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-1626-SM-2HMIR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NCIH2052 DepMap CRISPR Gene Dependency 1.0 2.50169 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-0626-SM-48U1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE195568_3_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48181 THEM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72522 GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.48026 GTEX-XQ3S-1726-SM-4BOOD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SIN3A-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 intermediate pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26115 GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SPIN2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.74357 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.50925 RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-1926-SM-3DB8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6879 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02179 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2171 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XXEK-1026-SM-4BRUW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 T84 COSMIC Cell Line Gene Mutation Profiles 1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 87.9993 TRAPPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52696 GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.64546 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 BHLHA15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1075 BT20 CCLE Cell Line Gene CNV Profiles -1.0 -2.44182 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HOXA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6298 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRO-1226-SM-48TDL GTEx Tissue Sample Gene Expression Profiles 1.0 1.00029 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02653 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02179 GSE76425_0_v_5_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07929 GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.15039 GTEX-WFG8-2326-SM-3GILF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 LN-229 COSMIC Cell Line Gene Mutation Profiles 1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9217 GSE230744,GSE237803_5_v_2_hira_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.20244 GSE98898_7_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE195786_3_v_1_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null C19orf47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11425 NCI-H1944 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26314 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02179 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.94078 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CENPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08899 Optic disc size GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 OLIG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.1415 Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE-9 COSMIC Cell Line Gene Mutation Profiles 1.0 null shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52029 Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.876256 KP1N DepMap CRISPR Gene Dependency 1.0 5.93193 Perturb_400_KO_NFE2L1_SRP333364 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.22177 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79601 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.87437 hsa-miR-4282 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 PSMD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49819 GSE221742,GSE221743_1_v_2_sipa1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SNMC-0926-SM-4DM5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.08202 B800-820 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.695 GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KDM4A ENCODE Transcription Factor Targets 1.0 null PMC12164972-FSB2-39-e70689-s001.pdf-2-LOC105369212_NR2F2-AS1_NR2F2 Rummagene Transcription Factor Associations 2026 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1552 abnormality of immune serum protein physiology GWASdb SNP-Phenotype Associations 1.0 0.584643 CAL72 DepMap CRISPR Gene Dependency 1.0 2.45465 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09597 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.63787 GTEX-RU72-1426-SM-46MUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE184087_4_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885172 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null miR-124_OE_GDS2657_770_human_HepG2 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null Primary somatosensory area, upper limb, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01408 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1 Rummagene Transcription Factor Associations 2026 1.0 null DBTRG-05MG COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PDE7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26648 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.66637 H3C6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39801 DPYSL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33538 Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 0.864338 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.908354 Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69398 CD56+_NKCells BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.47339 GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.959431 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.969448 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27021 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8349 RPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85321 SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1199 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null HSPB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39826 GSE135244_0_v_1_trdmt1_human RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57132 GTEX-RVPU-2226-SM-2XCAQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 ASL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38046 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12709 CAMSAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3688 Tassel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.688 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2948 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.82386 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28184 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MHH-NB-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28877 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAUDI COSMIC Cell Line Gene Mutation Profiles 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.72434 PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_8_v_11_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Bone mineral density (Ward's triangle area) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 ATP13A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62444 TRMT10C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06174 GTEX-SJXC-2026-SM-4DM6N GTEx Tissue Sample Gene Expression Profiles 1.0 0.890675 SK-LMS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE234289_4_v_1_rfx6_human RummaGEO Gene Perturbation Signatures -1.0 null PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 501A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32361 GTEX-Q2AH-0226-SM-48U1I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral preoptic area, PO1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08925 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.863764 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18313 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.31224 lateral preoptic nucleus, PO2 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48181 RAB3GAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88741 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 A549 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OIZH-2626-SM-2HMJM GTEx Tissue Sample Gene Expression Profiles 1.0 0.994012 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.2899 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.61137 liver HPA Tissue Gene Expression Profiles -1.0 -1.0777 PUF60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22155 mantle zone of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13713 Medullary cell_Kidney_Mouse CellMarker Gene-Cell Type Associations 1.0 null GTEX-RNOR-0926-SM-2TF56 GTEx Tissue Sample Gene Expression Profiles 1.0 1.015 GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.26518 GSE160765_2_v_1_twist1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-U8XE-0426-SM-3DB91 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.82142 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.28821 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.968684 GTEX-POMQ-0426-SM-3P61G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 1.95832 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24383 Primary somatosensory area, nose Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69825 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 1.1184 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DNM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34303 GTEX-WYJK-1626-SM-3NM9J GTEx Tissue Sample Gene Expression Profiles 1.0 0.864682 posteroventral (inferior) parietal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15755 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55G-0826-SM-2TC5U GTEx Tissue Sample Gene Expression Profiles 1.0 0.998706 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.638 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00255 GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null H2BC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24209 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GOTO COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RU1J-0226-SM-2TF5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.87633 COLO-680N COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XAJ8-0926-SM-47JXZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30673 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.37328 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56021 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46856 GTEX-VUSG-0626-SM-4KL1Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Trunk TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16481 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.992047 USF2 ENCODE Transcription Factor Targets 1.0 null IRF4-20064451-CD4+T-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RM2N-1726-SM-2TF55 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 496100576_HIP_dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.96174 Primary somatosensory area, mouth, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08894 daudi HPA Cell Line Gene Expression Profiles -1.0 -1.15888 GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Mammillary body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39892 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01059 GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.09463 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28176 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.334 GTEX-XAJ8-0226-SM-4GIB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.867 superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88528 H3K9me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11923 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 141.379 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210682_0_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null outer SZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.966642 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.192884 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NU-DUL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC-44 COSMIC Cell Line Gene Mutation Profiles 1.0 null fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 1.06887 Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08894 H3K9me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PPP1R12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.69088 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.41589 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03708 GTEX-UJHI-0226-SM-4IHJL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CTCF ENCODE Transcription Factor Targets 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OLIG3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5278 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28544 Brain Lower Grade Glioma_LGG_TCGA-CS-5397-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IQ motif, EF-hand binding site InterPro Predicted Protein Domain Annotations 1.0 null GSE184087_4_v_5_tert_human RummaGEO Gene Perturbation Signatures -1.0 null CCHCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08609 MRPL54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.69496 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE240030,GSE252532_0_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81304 MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13817 morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.073498 COLO684 DepMap CRISPR Gene Dependency 1.0 3.71731 USP48 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38477 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3500769-srep00875-s3.xls-CEBP-Time_4_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.940767 superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85839 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.15511 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.854902 GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SW1088 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_17548_KD_HMGN5_SRP354633 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 13.6227 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13814 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SETD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72269 basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18401 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1552 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FU97 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H522 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H4 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03198 Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6825 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XY-1626-SM-46MVN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lymph node HPA Tissue Protein Expression Profiles -1.0 -1.30116 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ABCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02797 GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TAL1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42916 SIN3A ENCODE Transcription Factor Targets 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BALL-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TMEM41A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99052 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06453 GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.1011 GSE242096,GSE242098_1_v_0_med1_mouse RummaGEO Gene Perturbation Signatures -1.0 null AR_01_323 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.67285 VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16435 GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09068 GTEX-S4UY-0426-SM-3K2AF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Agranular insular area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29131 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1184 JOSD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46787 CAPAN2 CCLE Cell Line Gene CNV Profiles -1.0 -1.34911 POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null ACVR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12226 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.520073 MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9015 GSE235066_7_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null PXR (PXR:RXR) MotifMap Predicted Transcription Factor Targets 1.0 null septal nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05725 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.893356 Intramuscular adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.885 Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1342 p1 part of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14817 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27062 dementia GWASdb SNP-Disease Associations 1.0 0.346921 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-W5WG-1626-SM-4LMKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.77682 GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.7851 Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X3Y1-0626-SM-3P5YS GTEx Tissue Sample Gene Expression Profiles 1.0 1.24323 NPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5498 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF3beta MotifMap Predicted Transcription Factor Targets 1.0 null CAPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29621 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.51854 PEX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1737 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90931 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25187 GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-0926-SM-2I5FU GTEx Tissue Sample Gene Expression Profiles 1.0 1.05341 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FMNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01781 GSE102467_1_v_0_pazopanib_human RummaGEO Drug Perturbation Signatures 1.0 null ECHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11889 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10656 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79425 inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46046 SP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870615 Lung-lung ciliated cell Tabula Sapiens Gene-Cell Associations 1.0 9.75957 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RWSA-0826-SM-2XCBF GTEx Tissue Sample Gene Expression Profiles 1.0 1.08199 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BECKER COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3758 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-P4PQ-2626-SM-33HC9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.904107 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null E2F5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02616 KMH2 CCLE Cell Line Gene CNV Profiles 1.0 1.91827 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SMC loading complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.569 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE184087_0_v_5_tert_human RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6175 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_NM-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.37547 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Megagametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FKBP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64991 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.02698 MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -1.36619 NFYA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.5108 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28877 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3129 HCC70 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9ac_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08147 B3GALNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31107 HPAC COSMIC Cell Line Gene Mutation Profiles 1.0 null PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 105.663 U178 CCLE Cell Line Gene CNV Profiles -1.0 -1.74026 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.62871 Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE212299_2_v_1_abi3_mouse RummaGEO Gene Perturbation Signatures -1.0 null paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6727 SLAIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58053 GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.934964 PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX Rummagene Transcription Factor Associations 2026 1.0 null HUH1 CCLE Cell Line Gene CNV Profiles 1.0 1.64381 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06578 mRNA_AES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 1.49836 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.38782 MDAMB361 CCLE Cell Line Gene CNV Profiles 1.0 2.36415 ChIP_SIN3A_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A498 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-O5YT-1826-SM-32PK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE145790_0_v_1_bruceantin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961264 MONOMAC1 DepMap CRISPR Gene Dependency 1.0 4.54083 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 EFO21 CCLE Cell Line Gene CNV Profiles -1.0 -2.44811 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.89824 GTEX-R53T-1326-SM-48FCQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 BHLHE23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19031 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null GTEX-XV7Q-2326-SM-4BRVZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles 1.0 1.06021 GSE174498,GSE174500_3_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-S4Q7-0226-SM-4AD5O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2908 GTEX-XUZC-1326-SM-4BRV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120612_4_v_5_etoposide_human RummaGEO Drug Perturbation Signatures -1.0 null CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.911421 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.73876 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 1.01867 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE234289_4_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902922 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.03481 Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JZ-01A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.869379 Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.8535 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.19055 outer SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14244 ELK1 ENCODE Transcription Factor Targets 1.0 null GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NOMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31641 GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04262 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894305 H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40597 Ciliated cell_Airway epithelium_Human CellMarker Gene-Cell Type Associations 1.0 null ventral entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00238 Hoof TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.769 Lung squamous cell carcinoma_LUSC_TCGA-56-1622-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-Unnamed_12_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE142210_11_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6798 Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.2942 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.92152 Seminal vesicle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 LENG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4806 Clara cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.989 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17545 GTEX-V1D1-0626-SM-4JBHN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null KM12 CCLE Cell Line Gene CNV Profiles 1.0 1.39611 RRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38819 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.3732 IM9 DepMap CRISPR Gene Dependency 1.0 2.82803 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null superficial stratum of POH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.4 GTEX-PWN1-1526-SM-48TDA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20632 SPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48728 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.38565 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28881 Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.828 Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40895 H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35191 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07236 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94206 GSE214505_0_v_1_akr1b1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1978 HCC1806 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null GAPVD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25669 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16816 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.4423 KIAA1671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73023 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59684 p3 portion of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14316 Cyanuric chloride DeepCoverMOA Drug Mechanisms of Action 1.0 0.33 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7037 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE185163_5_v_2_clic4_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE166783_3_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MAMDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29669 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EXOC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05015 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.62353 Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-SSA3-0126-SM-32QPU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.82368 PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6319 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XV7Q-0626-SM-4BRV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Inhibin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.821 amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831458 GTEX-OXRO-0011-R10A-SM-2I5EH GTEx Tissue Sample Gene Expression Profiles 1.0 1.23262 K029AX DepMap CRISPR Gene Dependency 1.0 13.4374 GSE213228_2_v_0_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 DDX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31227 mood disorder GWASdb SNP-Disease Associations 1.0 0.341146 AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null parasubthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.65495 MDAMB134VI Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.76332 ABC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831983 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.34333 SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.840449 GTEX-S7SE-0526-SM-2XCD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Inferior colliculus, dorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13462 alzheimer disease GWASdb SNP-Phenotype Associations 1.0 0.493579 BRI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44594 H2AFZ ENCODE Transcription Factor Targets 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.1575 GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.803455 mRNA_FEM1B_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.5957 POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.0505 GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43742 Perturb_14216_KO_Igf1r_SRP081104 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.3748 GTEX-S32W-2326-SM-2XCAW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25215 GTEX-U8T8-0326-SM-3DB93 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11701 KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18133 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24013 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8037 COR-L321 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PANC0327 CCLE Cell Line Gene CNV Profiles -1.0 -1.35422 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03058 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE221020,GSE221023_2_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10133 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Inhibin B complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.046 r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03809 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.41231 Shox2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4941 IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25813 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GRANTA-519 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.875241 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.6111 GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1072 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null bone marrow HPA Tissue Gene Expression Profiles -1.0 -1.0777 DIFI DepMap CRISPR Gene Dependency 1.0 5.92692 COLO320 DepMap CRISPR Gene Dependency 1.0 3.82825 OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03164 SC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE108084_3_v_2_epinephrine_human RummaGEO Drug Perturbation Signatures 1.0 null HDAC2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Inguinal canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.884 Colorectum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE158502,GSE158506_3_v_0_fat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SNOS-1726-SM-32PLN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Sarcoma_SARC_TCGA-WK-A8XO-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55652 GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.848463 SF1_01_271 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63018 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ATP5PD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08071 Excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-PX3G-0226-SM-3NB2C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 mediodorsal nucleus of thalamus_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.987815 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.97118 GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PSDG-0726-SM-2I5FN GTEx Tissue Sample Gene Expression Profiles 1.0 0.850587 ZCCHC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40263 GSE142210_11_v_6_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null SGSM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57488 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE119345_2_v_3_bexarotene_human RummaGEO Drug Perturbation Signatures 1.0 null SAPCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.47001 NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.965255 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5190-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.0777 L3HYPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16906 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 3.56348 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.12983 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE138024_2_v_3_rgs4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Primary somatosensory area, upper limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04803 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.96182 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-361 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.2769 FOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2952 Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38791 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25763 Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE153189_2_v_0_interferon gamma_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 inner CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898575 CHD2 ENCODE Transcription Factor Targets 1.0 null GSE149355_0_v_1_esrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.07039 PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55C-0626-SM-2TF4Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.862463 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSPB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70371 CCK-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.52628 Congenital ptosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.198 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MYC ChEA Transcription Factor Targets 1.0 null GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92228 PPAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45924 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.946245 primary auditory cortex (core)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.857001 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain morphology (MOSTest) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.6189 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.85184 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2334 HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28877 GSE225656_2_v_3_tsc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.18029 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0726-SM-4BRWF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Msx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6903 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2324 REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHPK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15041 GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.720518 GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QESD-1526-SM-2S1QT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871923 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32131 psychotic disorder GWASdb SNP-Disease Associations 1.0 0.300667 Autosomal recessive nonsyndromic deafness 84A DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.798 Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11401 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53466 GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles 1.0 0.82428 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XUW1-0726-SM-4BOP5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.8853 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.661 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AGPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52159 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157960_0_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-V955-0926-SM-4JBJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0643 GTEX-UPIC-1626-SM-4IHKT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01871 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUPT3 CCLE Cell Line Gene CNV Profiles -1.0 -1.54923 ABHD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21065 HH COSMIC Cell Line Gene Mutation Profiles 1.0 null COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.81309 POLR3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5699 NCI-H1836 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QLQW-1326-SM-2S1QS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Pentadecanoyl EA DeepCoverMOA Drug Mechanisms of Action 1.0 0.27 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3925-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC174 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35117 H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49575 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.096023 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CACTIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15517 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.82192 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.96837 Parasubiculum, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02385 CXCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14251 GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02499 CCDC12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99633 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE261563_9_v_8_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49617 GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.02677 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83519 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52747 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -2.12468 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.944334 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.30116 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17592 Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14921 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE171837_3_v_2_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943745 spinalcordlower BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.856553 Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22343 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.87671 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90919 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH196 CCLE Cell Line Gene CNV Profiles 1.0 2.07056 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 RCOR1 ENCODE Transcription Factor Targets 1.0 null GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 layer 1 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07955 GSE48812_2_v_5_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUJ4-1226-SM-4BOPD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1623 CCLE Cell Line Gene CNV Profiles 1.0 1.5173 Posterior pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21441 GTEX-R55E-0006-SM-2TC5G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CRELD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82234 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE128634,GSE128636_4_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.36271 Retrosplenial area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07223 WFS1_KO_GDS4526_111_mouse_brain GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SETDB1_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventral tegmental area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33293 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51266 ventrolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46576 small intestine HPA Tissue Protein Expression Profiles 1.0 1.18262 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC9 ChEA Transcription Factor Targets 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.22876 STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null A_CA_04_2009_7dayMOI-10^4_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.40208 RPMI-8402 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21888 GSE139016_0_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.961997 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.923989 ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.093 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.05982 GTEX-WQUQ-1426-SM-3MJFD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.093 ALS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10447 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3062 Breast TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-U4B1-0826-SM-4DXTW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 LRP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67375 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.002 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 1.42112 CCF-STTG1 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1478 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857694 Perturb_528_KO_NFE2L1_SRP333364 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.30871 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.87134 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.60451 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46678 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.86274 PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null BTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05649 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE134029_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44436 GSE230573_1_v_0_dcaf1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE157684,GSE173391_0_v_1_rgcc_human RummaGEO Gene Perturbation Signatures 1.0 null striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.63404 mantle zone of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50413 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null miR-124_OE_GDS2657_771_human_HepG2 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6133 PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null subcallosal cingulate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.926267 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0724 hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.7549 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.943348 Perturb_12127_KO_Dnmt3a_SRP033096 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.03649 GSE135350_3_v_5_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 1.48325 PCI-4B COSMIC Cell Line Gene Mutation Profiles 1.0 null PPP1R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83196 PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_hyp-HIF2_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYO1 DepMap CRISPR Gene Dependency 1.0 2.66636 Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24653 GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.88045 CDCA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23171 GTEX-XUZC-1026-SM-4BOPY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CRX-20693478-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TNFRSF10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34985 Presubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10886 GTEX-XYKS-0526-SM-4BRW2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05492 GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15334 POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6706 GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Branchiooculofacial syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.048 GTEX-QV31-0726-SM-3GAEG GTEx Tissue Sample Gene Expression Profiles 1.0 0.904794 PLEKHG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23812 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 TMEM254 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27551 GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 1.0873 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Dicumarol DeepCoverMOA Drug Mechanisms of Action 1.0 0.25 GTEX-VJYA-0926-SM-4KL1N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 outer CP in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21548 GSE166783_8_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NCI-H1105 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE154197_1_v_2_ints13_human RummaGEO Gene Perturbation Signatures 1.0 null GSE172019_2_v_8_rnf2_human RummaGEO Gene Perturbation Signatures 1.0 null PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Gene_ID_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.4943 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01651 GTEX-XUW1-1126-SM-4BONZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Autosomal dominant intellectual developmental disorder 22 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.491 HIF1A_01_224 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.63916 striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2342 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEL270 DepMap CRISPR Gene Dependency 1.0 2.7143 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.3587 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-OLIG2_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.07825 GSE114284_2_v_3_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2 Rummagene Transcription Factor Associations 2026 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32749 Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.954883 Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPN-0226-SM-48TBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE171837_3_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAL1::TCF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3636 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.04872 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06427 periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12933 NMU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17829 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5617 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.990248 AMFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25019 lateropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0824 GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 496100519_HIP_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.16391 GTEX-T6MN-0126-SM-32PLP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hsa-miR-4775 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 HES4 Pathway Commons Protein-Protein Interactions 1.0 null TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894305 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0704 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45909 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MONOMAC6 CCLE Cell Line Gene CNV Profiles -1.0 -1.90473 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null Partial androgen insensitivity syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.049 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1512 POLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62631 FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7218 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42C-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.854218 mammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50226 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84685 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15256 GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MO-1226-SM-4DM5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901966 depression GWASdb SNP-Phenotype Associations 1.0 0.390708 PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-S32W-0426-SM-4AD6H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 Ruboxistaurin DeepCoverMOA Drug Mechanisms of Action 1.0 0.77 Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCC1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60592 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ATP2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23321 FKBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37352 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49732 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VI, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00182 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29012 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55886 EW7 DepMap CRISPR Gene Dependency 1.0 2.97687 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9126 MTFMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27314 UPCISCC152 DepMap CRISPR Gene Dependency 1.0 2.06136 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL-39 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0824 GTEX-OOBJ-0526-SM-48TDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.15512 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39656 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WFJO-1026-SM-3GIKL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 METTL2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.51202 LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9026 GTEX-P4QT-1626-SM-2S1NP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.32187 NCI-H520 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0299 GSE216273,GSE216292_0_v_8_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Sulforaphane DeepCoverMOA Drug Mechanisms of Action 1.0 0.5 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE128634,GSE128636_1_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MONOMAC1 CCLE Cell Line Gene CNV Profiles -1.0 -2.08394 E2F6 ENCODE Transcription Factor Targets 1.0 null GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RWS6-0526-SM-4GIAJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0643 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MO-1426-SM-4DM73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.860055 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE236280_0_v_1_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPN-0011-R1A-SM-2I5GB GTEx Tissue Sample Gene Expression Profiles 1.0 0.987142 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.881415 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15384 superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92972 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02732 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE224004,GSE224005_0_v_8_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0281 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06659 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.21823 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles 1.0 1.41122 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COR-L32 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10806738-mmc2.xlsx-Table_S2-Table_S2_Table_of_significantly_adjusted_p-valued_0_05_down-regulated_genes_log2FC_-1_in_MAX-R60Q_transfected_HEK293_cells_relative_to_MAX-WT_transfected_cells_MAX Rummagene Transcription Factor Associations 2026 1.0 null posteroventral (inferior) parietal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.41449 BRCA1 ENCODE Transcription Factor Targets 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.870071 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46918 SEC62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22297 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40376 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2554 GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE156708_1_v_0_fbxo11_human RummaGEO Gene Perturbation Signatures -1.0 null ILF2_02_88 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.12928 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A685-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJHI-1326-SM-4IHJO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WY7C-0426-SM-3NB3C GTEx Tissue Sample Gene Expression Profiles 1.0 0.911557 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58119 AP1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.55878 TRAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.098 PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1 Rummagene Transcription Factor Associations 2026 1.0 null GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE114013,GSE114014_0_v_4_itraconazole_human RummaGEO Drug Perturbation Signatures -1.0 null G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 skeletalmuscle BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.34788 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961953 GSE235066_4_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.4643 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.6359 HUH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-O5YT-1326-SM-3MJGR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NB4 DepMap CRISPR Gene Dependency 1.0 3.09953 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01855 GTEX-WHSB-1326-SM-3LK6W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Autosomal dominant nonsyndromic deafness 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.233 lateral periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.40597 GTEX-OOBJ-0426-SM-3NB1S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-VJYA-1126-SM-3GIJU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.835106 C10orf105 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.055 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.7716 U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01973 GTEX-TSE9-0626-SM-3DB8B GTEx Tissue Sample Gene Expression Profiles 1.0 0.869227 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.936154 MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128634,GSE128636_4_v_0_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null SMARCD1-25818293-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.885538 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961953 TC138 DepMap CRISPR Gene Dependency 1.0 4.04788 GTEX-VUSG-0426-SM-3GIKD GTEx Tissue Sample Gene Expression Profiles 1.0 0.897988 GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MYBL2 ChEA Transcription Factor Targets 1.0 null medial tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41427 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WVLH-0626-SM-3MJG7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88965 H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24091 GTEX-NL4W-0011-R8a-SM-2I3G4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.844372 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.527 PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF Rummagene Transcription Factor Associations 2026 1.0 null PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE119978,GSE180930_2_v_7_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5001 superficial stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00238 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3663 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.8243 GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03379 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.957662 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Gall bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51567 TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.91918 JSC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-0726-SM-3DB8O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hsa-miR-4640-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SCG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09765 GSE145249_1_v_3_ppm1g_human RummaGEO Gene Perturbation Signatures 1.0 null primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36319 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.262025 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0303 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null striatum_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.835106 GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.3394 PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-up-Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null Lassa Fever Virus_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.10197 GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CIAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31078 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.197 karpas707 HPA Cell Line Gene Expression Profiles -1.0 -1.15888 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01574 hsa-miR-1185 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE158834_7_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210373_0_v_1_cntnap4_human RummaGEO Gene Perturbation Signatures 1.0 null Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.015 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.034854 GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06427 TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.973 r9 portion of vagal motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03087 layer 3 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61566 GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-V1D1-0826-SM-3P5ZA GTEx Tissue Sample Gene Expression Profiles 1.0 1.12095 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null VPS26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09955 Perturb_10320_KO_HDAC1/HDAC2_SRP255858 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.57932 ML-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62801 YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM229A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43723 ENSG00000284691 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0194 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45845 RL95-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1793 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92717 superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39428 follicle-stimulating hormone complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.108 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11417 GSE238005_0_v_3_c9orf72_human RummaGEO Gene Perturbation Signatures -1.0 null ICMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01121 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CCNJ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.34389 NCI-H358 COSMIC Cell Line Gene Mutation Profiles 1.0 null dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46029 Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79241 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W9-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06382 SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.958182 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14647_KD_SOX9_SRP308338 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.48753 GSE238116_1_v_2_egr1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.97738 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30429 Melanocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.643 GSE76425_0_v_12_lenalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null Monobrow GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.87369 GTEX-T6MN-0926-SM-32PLX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8774 GTEX-R55E-1126-SM-48FDZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.954511 OCT4-21477851-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.960757 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2 ChEA Transcription Factor Targets 1.0 null SIN3A ChEA Transcription Factor Targets 1.0 null GTEX-Q734-0626-SM-2I3EF GTEx Tissue Sample Gene Expression Profiles 1.0 0.93926 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 3.42938 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.913237 GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15257 GSE213228_2_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null PSMB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58011 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.61218 Ependymal cell_Brain_Mouse CellMarker Gene-Cell Type Associations 1.0 null PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.1437 Rfx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.0607 QGP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.70275 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-1926-SM-32PM3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XPVG-0726-SM-4B658 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922989 TOMM40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00033 PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521 Rummagene Transcription Factor Associations 2026 1.0 null SEC14L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21251 Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.41306 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Dlx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8673 PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK Rummagene Transcription Factor Associations 2026 1.0 null mRNA_SALL4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13462 ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30596 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.83596 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30733 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04263 microtubule cytoskeleton GO Cellular Component Annotations 2025 1.0 null PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PLZ5-2026-SM-2S1O4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-Q2AG-0826-SM-2HMKF GTEx Tissue Sample Gene Expression Profiles 1.0 1.05717 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.474 SP1 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Primary somatosensory area, mouth, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29131 pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19999 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13815 MAN1A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.7068 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SN8G-1526-SM-4DM79 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15595 SIN3A_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XBEW-0126-SM-4AT66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.86454 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE133087_1_v_2_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LI7 CCLE Cell Line Gene CNV Profiles 1.0 1.33377 EFM-19 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-NL3H-0011-R4a-SM-2I3GK GTEx Tissue Sample Gene Expression Profiles 1.0 0.9751 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31228 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.855983 GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE131161_5_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null smc1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.945 TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00727 GSE184087_0_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null SEPHS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42894 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3001 layer 3 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82536 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, mouth, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48952 olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10901 TEX41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.79548 FTSJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14113 GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30705 GTEX-RU1J-1726-SM-2TF5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46918 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supramammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37043 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-QVUS-0626-SM-447CC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE80098,GSE80366_0_v_8_progesterone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.1631 SP in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865593 GTEX-S4Q7-1526-SM-3K2AG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBJ-0826-SM-3NB2K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.75846 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36356 CAKI2 CCLE Cell Line Gene CNV Profiles 1.0 2.59998 NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null NINL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71567 NCI-H1688 COSMIC Cell Line Gene Mutation Profiles 1.0 null CCDC93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9533 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4854-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12128 VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.990245 C2CD2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71136 GSE155031_5_v_0_dextran_human RummaGEO Drug Perturbation Signatures -1.0 null KLK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35726 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71195 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06086 FAM156B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59013 hsa-miR-466 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3172 METTL27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07377 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.00976 ABT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42967 primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.835369 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.39122 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6257 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.8494 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.85556 SNU-423 COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47592 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null C3orf52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66221 BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43943 ELF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7903 TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8558 19377508-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null hsa-miR-590-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 amygdaloid complex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.968773 Mitochondrial respiratory chain complex IV COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.983 paraventricular nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22396 GTEX-X4XY-1026-SM-46MVX GTEx Tissue Sample Gene Expression Profiles 1.0 0.934736 GTEX-NFK9-0526-SM-2YUNL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 mRNA_NRIP1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31227 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50348 GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 U-87-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE135350_3_v_0_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4314 PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null PA1 DepMap CRISPR Gene Dependency 1.0 4.6682 GTEX-VUSG-0126-SM-4KL1X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WHSE-1126-SM-3NMBU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 REST_PFSK-1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS746T CCLE Cell Line Gene CNV Profiles -1.0 -1.55532 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPM-2626-SM-33HC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987534 SCS214 DepMap CRISPR Gene Dependency 1.0 2.37503 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7134 H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157555,GSE157556_3_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R53T-1626-SM-3GAEW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE178714_6_v_0_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.56021 BL3588 (HIST1H3A) NURSA Protein Complexes 1.0 null FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.6888 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null Subiculum, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04803 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12507 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.065757 Perturb_1088_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.69913 CEBPG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.834 H3-7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04978 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.85993 PEO1 COSMIC Cell Line Gene Mutation Profiles 1.0 null E2F7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5746 GLIS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72783 LUZP1-20508642-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.86729 GTEX-WYVS-2526-SM-3NMAT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6035 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.6635 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.33304 MYC-20876797-MEDULLOBLASTOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 DDX39B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06456 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4179 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29482 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01419 GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 0.87303 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70056 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2522 Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75437 interstitial nucleus of Cajal, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890804 YY1 ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18598 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28877 GSE108500_1_v_0_foxp1_human RummaGEO Gene Perturbation Signatures 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JC-1726-SM-4DM6U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-T6MN-0011-R8A-SM-32QP3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.836109 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Thorax TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GTEX-OXRO-0326-SM-33HBM GTEx Tissue Sample Gene Expression Profiles 1.0 1.11134 MCF7 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.667709 colon HPA Tissue Protein Expression Profiles -1.0 -0.81701 AGPAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.89364 GSE206729_5_v_1_trps1_human RummaGEO Gene Perturbation Signatures -1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.6039 H3K4me1_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2971 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.7617 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.54172 Agranular insular area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43326 inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12962 TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2618 G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null Uterus-ciliated epithelial cell Tabula Sapiens Gene-Cell Associations 1.0 0.544498 ATRFLOX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null ADCY5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.86961 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE162276_4_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null QGP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.75983 primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.956547 PRDM9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17778 medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.851899 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV2_ETV2 Rummagene Transcription Factor Associations 2026 1.0 null CLK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08584 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCFC1 ENCODE Transcription Factor Targets 1.0 null ELF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3155 GTEX-SIU7-0226-SM-4BRX2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tauopathy GWASdb SNP-Disease Associations 1.0 0.580046 H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sclerosteosis 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.577 TYK-NU COSMIC Cell Line Gene Mutation Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.41162 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF341 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29108 RDH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59325 GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 MATN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33966 GTEX-WHPG-0226-SM-3NMB9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897677 Tadalafil DeepCoverMOA Drug Mechanisms of Action -1.0 -0.37 RBPJ ChEA Transcription Factor Targets 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4297 496100445_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22731 GTEX-QXCU-0326-SM-2TC63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12507 GTEX-PSDG-1026-SM-48TCV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05333 H3K9me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null DBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11426 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.7173 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.81708 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3566 lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05995 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system disease GWASdb SNP-Disease Associations 1.0 0.088567 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868116 HUO9 COSMIC Cell Line Gene Mutation Profiles 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null entorhinal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23652 Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24916 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54843 NCI-H820 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23652 A704 COSMIC Cell Line Gene Mutation Profiles 1.0 null VMRC-RCZ COSMIC Cell Line Gene Mutation Profiles 1.0 null J82 DepMap CRISPR Gene Dependency 1.0 6.23724 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06427 GSE148263_6_v_0_trim3_human RummaGEO Gene Perturbation Signatures 1.0 null rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916744 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null HSFX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38037 GSE232631_4_v_3_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PF-04418948 DeepCoverMOA Drug Mechanisms of Action 1.0 0.29 Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26165 GSE160817_7_v_9_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1239 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55886 GTEX-O5YW-1826-SM-2YUN2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE157960_2_v_1_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RN64-1626-SM-48FD7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09482 GTEX-WK11-0526-SM-3NB3O GTEx Tissue Sample Gene Expression Profiles 1.0 0.833205 Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null JEG-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00535 GTEX-RUSQ-0426-SM-47JWR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 KNS-42 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE125014_6_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null SNU16 CCLE Cell Line Gene CNV Profiles -1.0 -1.44425 NB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.49222 PSMD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1452 BL5015 (RBM34) NURSA Protein Complexes 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PSMA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62109 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.3193 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.2758 intermediate stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25184 CHSA0108 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 CML-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.07044 GSE210383_0_v_1_trim71_mouse RummaGEO Gene Perturbation Signatures -1.0 null episupraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.4012 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.828303 496100434_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.26998 TCF7L2 ENCODE Transcription Factor Targets 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FLO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36457 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.88609 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.897046 GTEX-UJMC-0326-SM-3GAE2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.97716 hsa-miR-583 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.70181 GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 mania GWASdb SNP-Phenotype Associations 1.0 0.717203 GSE184087_0_v_3_tert_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S7SF-2226-SM-3K2BG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 WFS1_KO_GSE33372_395_mouse_hypothalamus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14645 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 UACC893 DepMap CRISPR Gene Dependency 1.0 2.92929 GTEX-VUSG-0526-SM-4KL22 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.0501 NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE189683_3_v_2_rif1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.91885 SIN3B ChEA Transcription Factor Targets 1.0 null RPS27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03212 GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.15598 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.922791 CUL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75269 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.989039 gallbladder HPA Tissue Protein Expression Profiles 1.0 1.18262 P-loop containing nucleoside triphosphate hydrolase InterPro Predicted Protein Domain Annotations 1.0 null GTEX-U8XE-1926-SM-3DB98 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5357 YPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10176 Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.645 GTEX-X8HC-1626-SM-46MWE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 COL6A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.87102 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE221742,GSE221743_1_v_0_sipa1_human RummaGEO Gene Perturbation Signatures 1.0 null Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43466 mammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55404 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06602 muscle GTEx Tissue Gene Expression Profiles -1.0 -1.07066 GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.6801 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6173 Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.03896 Pharynx TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE231648_1_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39711 Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RWS6-0426-SM-47JXH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56199 PRCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53395 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.99557 DMRTA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9645 GTEX-WFG7-2326-SM-3GIKV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.8316 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.77386 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.1098 PECAPJ41CLONED2 CCLE Cell Line Gene CNV Profiles -1.0 -2.04785 DCAF12L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05593 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MOLP-8 COSMIC Cell Line Gene Mutation Profiles 1.0 null ERLIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42523 GSE128730_3_v_2_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE207582_2_v_1_testosterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XQ8I-0826-SM-4BOOE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GTEX-XBED-1326-SM-4AT4F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 THRAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00074 KAT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16125 Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44019 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.886334 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7997-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55961 GSE128634,GSE128636_2_v_3_foxo1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XXEK-1626-SM-4BRUZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UJMC-2026-SM-3GADR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860232 GSE216273,GSE216292_0_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null