association dataset threshold value standardized value protein binding GO Molecular Function Annotations 2015 1.0 null ventrolateral prefrontal cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.3639 WRNIP1 ENCODE Transcription Factor Targets 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19046 MSGN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76718 GSE240027,GSE240030_5_v_0_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null HS-578-T COSMIC Cell Line Gene Mutation Profiles 1.0 null CEBPD ChEA Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00886 GTEX-UJMC-0326-SM-3GAE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35505 ZNF81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19508 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08313 496100420_PCx_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22406 ANXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66846 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF Rummagene Transcription Factor Associations 2026 1.0 null FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3644 BICR10 DepMap CRISPR Gene Dependency 1.0 2.95061 N4BP2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89074 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AP1S1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20651 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.994781 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDC25A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3536 nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36507 hsa-miR-511 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06287 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.03664 SRMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54682 SW 982 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.947422 GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K36me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54603 NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT-549 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.934599 SLC9A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.49678 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08004 H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE228727_2_v_0_dapagliflozin_mouse RummaGEO Drug Perturbation Signatures -1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF319 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17244 superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37273 CBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02116 GTEX-OHPL-1326-SM-3MJGG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11423 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.9622 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null STAT5A ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE119498_2_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null ODF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02435 GTEX-P44H-0226-SM-2XCEU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Spinal nucleus of the trigeminal, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09982 ZNF143 ENCODE Transcription Factor Targets 1.0 null TMEM127 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55878 ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.68194 Necrosis CTD Gene-Disease Associations 1.0 1.50979 BL1013 (INTS3) NURSA Protein Complexes 1.0 null GTEX-XUYS-0226-SM-47JX1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08438 EGR1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.028039 SNU-61 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WWTR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19063 MRPL28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6369 H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFYA ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61855 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null OSGIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78331 SF126 CCLE Cell Line Gene Expression Profiles -1.0 -1.69218 SISO COSMIC Cell Line Gene Mutation Profiles 1.0 null G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.18133 Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.22466 abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.092375 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975059 CEBPD-23245923-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.02671 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4424 H3K79me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91204 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.58711 Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMBIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95519 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59304 BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.12206 POLR2A_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NOTCH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61052 GTEX-SUCS-0526-SM-4DM56 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0616 GSE152699,GSE152723_3_v_2_vemurafenib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-VUSG-0426-SM-3GIKD GTEx Tissue Sample Gene Expression Profiles 1.0 0.906703 HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1755 DepMap CRISPR Gene Dependency 1.0 2.10414 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.96985 testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE234340_12_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-3940-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CALML6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.33064 H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SM-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.980783 GSE207611,GSE207612_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874212 IZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84444 MAP2K1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38778 HCC1569 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OIZG-1126-SM-2HMIU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE231648_4_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC3HAV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98708 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5277 GTEX-TKQ2-1826-SM-33HB2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899056 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null NCI-H446 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.964396 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880971 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.11768 NUGC2 CCLE Cell Line Gene CNV Profiles 1.0 1.93277 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.961286 hippocampus (hippocampal formation)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28504 POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEFL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.72945 UBC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10433 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17815 stratum lacunosum-moleculare of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66222 CXCL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68224 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12323 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47858 METTL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21482 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2557 PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PPARG ChEA Transcription Factor Targets 1.0 null superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99232 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LV-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.97216 APOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24906 heparin_homo sapiens_gpl570_gse12710 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Bed nuclei of the stria terminalis, posterior division, transverse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19053 PML ENCODE Transcription Factor Targets 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null skin_5e HPA Tissue Sample Gene Expression Profiles -1.0 -1.34457 H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NCI-H2342 COSMIC Cell Line Gene Mutation Profiles 1.0 null PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF587B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37839 BCAT-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27ac_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles 1.0 0.895433 H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100326_TCx_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.44009 DNASE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29043 orbital frontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058351 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887158 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FLI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null URI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10488 MXI1 ENCODE Transcription Factor Targets 1.0 null 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.34534 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null PEMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72622 ELF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UQCR10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57224 TSPOAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52812 MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.41342 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-0726-SM-47JY5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null GTEX-WH7G-0526-SM-3NMBI GTEx Tissue Sample Gene Expression Profiles 1.0 0.961421 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02246 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49412 NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.97323 GTEX-WYJK-1426-SM-3NM8V GTEx Tissue Sample Gene Expression Profiles 1.0 0.952091 GTEX-R55F-0226-SM-48FCI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE210682_2_v_1_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 0.94951 MIER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23395 amygdaloid complex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.850288 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877651 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27088 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15721 embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.867178 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36001 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.063602 IRF1 ENCODE Transcription Factor Targets 1.0 null TUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94969 STEEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31272 POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.5369 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null esophagus_5a HPA Tissue Sample Gene Expression Profiles -1.0 -1.24487 GTEX-QMRM-1726-SM-2S1QG GTEx Tissue Sample Gene Expression Profiles 1.0 1.03959 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53326 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-0226-SM-3NB1Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.839495 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6231 NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98927 GSE195568_3_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07409 SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.09172 TET2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54241 Basal part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.05 GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 1.40394 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAUDI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.03112 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE135514_8_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_3_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsomedial preoptic area, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75274 SPI1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SEZ6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19089 GTEX-XQ3S-1126-SM-4BOPK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.1092 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X8HC-0526-SM-4E3JA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE114284_4_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.02144 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.31919 Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAFF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.585 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_9_v_6_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null NPAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47334 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2642 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 496100382_PCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.065 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles 1.0 1.00831 ANKRD16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85327 PK-45P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17189 GTEX-WEY5-0426-SM-3GIKT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FAM117B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8557 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SBC5 CCLE Cell Line Gene Expression Profiles 1.0 1.36923 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HCC1897 CCLE Cell Line Gene CNV Profiles 1.0 1.48011 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 1.17695 Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.826796 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null P12-ICHIKAWA COSMIC Cell Line Gene Mutation Profiles 1.0 null MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OMC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OIZI-0226-SM-2XCEE GTEx Tissue Sample Gene Expression Profiles 1.0 1.45728 CYP2U1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93323 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles 1.0 1.34511 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2095 STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19951 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4630-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8197658-NIHMS1703954-supplement-Table_S4.xls-Sheet1-Table_S4_List_of_differentially_expressed_genes_near_which_SALL4_CUT_RUN_peaks_were_annotated_related_to_Figure_3_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.863435 ACO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37575 ZNF99 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06103 GSE206870,GSE206872_3_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0318 H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_10_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.98033 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SUPT11 CCLE Cell Line Gene Expression Profiles 1.0 1.51923 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07917 NCI-H196 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Chromium levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 ABHD13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44663 POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75345 orbital frontal cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.73379 Adventitious root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.606 STAT1 ENCODE Transcription Factor Targets 1.0 null GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837275 PHF10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56336 KLE DepMap CRISPR Gene Dependency 1.0 2.60532 C2BBE1 CCLE Cell Line Gene CNV Profiles -1.0 -1.47305 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GM12878 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 2.19221 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-0326-SM-4DXUJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13901 COLO-320-HSR COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF804A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.85288 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1693 CCLE Cell Line Gene Expression Profiles 1.0 3.40251 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5023 GTEX-T6MN-0011-R1A-SM-32QOY GTEx Tissue Sample Gene Expression Profiles 1.0 0.875309 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-XUJ4-1126-SM-4BOPC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27723 REC1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33601 GSE112761,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.3639 GTEX-PVOW-0008-SM-48TE8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899036 ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.665 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.04691 H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57162 chr1_74211471_A_G_b38 GTEx eQTL 2025 1.0 3.19974 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2 ENCODE Transcription Factor Targets 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5362 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMMY-0226-SM-33HBA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.839375 HDAC2 ENCODE Transcription Factor Targets 1.0 null PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null colonrectum_a HPA Tissue Sample Gene Expression Profiles -1.0 -0.89137 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46301 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4324 HCFC1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE187006_0_v_1_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null SKMEL3 CCLE Cell Line Gene Expression Profiles 1.0 1.4328 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF354C JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null m1Lim (VL) part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09342 H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CANT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66341 GSE127790_13_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null BTG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80699 r7 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06714 intermediate stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21361 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 PAX5 ENCODE Transcription Factor Targets 1.0 null ZNF345 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91327 endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96343 GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.37655 skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 SKBR3 DepMap CRISPR Gene Dependency 1.0 2.09093 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.36419 GTEX-T6MO-1526-SM-4DM57 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 HHV-8_72Hour_18587055_GSE6489 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.69041 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.91784 SLC41A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.33273 H3K4me1_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles -1.0 -1.40608 CCDC22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28801 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09236 NMCG1 DepMap CRISPR Gene Dependency 1.0 2.30852 NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCT-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.1637 HOXC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.5436 Retrosplenial area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64741 GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SK-MEL-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00524 DEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73116 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.4982 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.48124 hl60 HPA Cell Line Gene Expression Profiles 1.0 1.49848 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10517 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28824 EGR1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRMT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49963 FBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41942 liminal part of the r8 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4582 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.0979 r7 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81684 NO11 DepMap CRISPR Gene Dependency 1.0 12.2775 GTEX-S4UY-0008-SM-3NM8H GTEx Tissue Sample Gene Expression Profiles 1.0 0.838345 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.890311 paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.85923 GTEX-WHWD-0826-SM-3LK6R GTEx Tissue Sample Gene Expression Profiles 1.0 0.959511 DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28279 ARHGEF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21672 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_all_ELK1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.18853 DYNC1H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.67025 Smoking initiation GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.5699 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940506 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53307 DENND1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43056 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3054 JHOS2 CCLE Cell Line Gene Expression Profiles 1.0 2.02362 Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62844 SARS-CoV MA15_Day1-PFU-10^4_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.95113 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02388 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIWIL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29146 CDC42EP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69695 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16774 RELCH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2816 kidney HPA Tissue Gene Expression Profiles 1.0 0.954167 U138MG CCLE Cell Line Gene CNV Profiles -1.0 -2.13552 SW 1990 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.947422 chr1_74200590_C_T_b38 GTEx eQTL 2025 1.0 1.58131 JARID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32952 LPCAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95875 GATA2 ENCODE Transcription Factor Targets 1.0 null TULP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99891 HCC1395 CCLE Cell Line Gene CNV Profiles -1.0 -2.24014 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF15-26573619-CHIP-SEQ-HEK293-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RRP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03985 VN1R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73595 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cecum cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.23 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07052 GTEX-WFON-0926-SM-4LVMK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MAPKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37815 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.30224 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SF3B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64251 PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.0492 NFIC ENCODE Transcription Factor Targets 1.0 null STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0008-SM-3NM9Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.10495 ELP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96832 GSE149355_0_v_1_esrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07541 TP53 ChEA Transcription Factor Targets 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84097 Cortical amygdalar area, anterior part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87746 SPI1 ChEA Transcription Factor Targets 1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SSA3-0002-SM-3P61R GTEx Tissue Sample Gene Expression Profiles 1.0 1.11918 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STK11IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82033 SIKE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67664 mantle zone of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20486 upper basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57416 POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06073 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.41771 NAP1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64736 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877963 Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22362 periventricular stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1676 NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.33 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SIPA1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24389 NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.974068 hsa-miR-4476 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Rectum cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.505 PMC3712200-584604.f1.pdf-47-MYPOP_MYPOP Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TML8-1226-SM-32QON GTEx Tissue Sample Gene Expression Profiles 1.0 1.21493 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4075-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44796 DLL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11717 KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06183 POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Achene TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.933 CHAGO-K-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OXTR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25502 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 soft tissue HPA Tissue Protein Expression Profiles -1.0 -0.856547 ZNF226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35431 arteriosclerotic cardiovascular disease GWASdb SNP-Disease Associations 1.0 0.463438 K562 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.41622 MRPL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26721 Subcutaneous tissue cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.109 peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20364 SNX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76945 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.14575 H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25027 PLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35146 primary motor cortex (area M1, area 4)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.83706 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062453 chr1_74208889_T_G_b38 GTEx eQTL 2025 1.0 3.14641 SPSB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53727 H3K27ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.836468 GSE234340_1_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null smooth muscle HPA Tissue Gene Expression Profiles -1.0 -1.27826 HCC1833 CCLE Cell Line Gene Expression Profiles 1.0 1.6291 MYF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45989 GTEX-W5X1-1426-SM-3GIKH GTEx Tissue Sample Gene Expression Profiles 1.0 1.28416 Rectum adenocarcinoma_READ_TCGA-DC-6683-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPG11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73123 ZNF467 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65467 abnormality of the face GWASdb SNP-Phenotype Associations 1.0 0.111021 POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TUBGCP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17338 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1187 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE147662_3_v_5_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03092 Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SP in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.825265 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.261 APMAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.248 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.26207 Cortical amygdalar area, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2742 SP1 ENCODE Transcription Factor Targets 1.0 null TRIM36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74561 SW1417 COSMIC Cell Line Gene Mutation Profiles 1.0 null YMB-1-E COSMIC Cell Line Gene Mutation Profiles 1.0 null RPS29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11552 PMS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.47788 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38663 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV1-20927104-GIST48-HUMAN ChEA Transcription Factor Targets 2022 1.0 null subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33686 Anterior cingulate area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3341 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inner CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.921215 HSFX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47124 H3K4me1_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MRPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12958 SNX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35984 CERS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17925 H2AFZ ENCODE Transcription Factor Targets 1.0 null GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MAGI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58319 NCI-H847 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02145 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.910017 intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57896 UDSCC2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Metabolite levels (X-11787) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9007 hsa-miR-4420 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M8-01A-21R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.3704 FOXM1 ENCODE Transcription Factor Targets 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.26874 FBXW8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69278 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29946 GSE224294_3_v_2_ngly1_human RummaGEO Gene Perturbation Signatures -1.0 null ZNF540 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12236 MAMDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3081 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.81202 127399 DepMap CRISPR Gene Dependency 1.0 6.12385 Leucine rich repeat 4 InterPro Predicted Protein Domain Annotations 1.0 null RPH3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53027 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902128 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CYB5D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96507 POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18878 FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22104 Medullary reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21664 GTEX-XUJ4-1426-SM-4BONT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ESS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Supramammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67419 spleen HPA Tissue Protein Expression Profiles -1.0 -0.856547 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S33H-1126-SM-2XCB6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.905178 chr1_74200058_A_T_b38 GTEx eQTL 2025 1.0 5.46354 PTPRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54573 Prostate adenocarcinoma_PRAD_TCGA-HC-A76W-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.30742 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.880982 Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.57858 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21388 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-2326-SM-46MW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHPG-0626-SM-3NMBD GTEx Tissue Sample Gene Expression Profiles 1.0 1.03715 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.971884 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.48139 GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles 1.0 0.831649 KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69807 DHX40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3605 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.920323 TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ADPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08403 IKBKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24152 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0426-SM-4B66A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMK1-0926-SM-4B66X GTEx Tissue Sample Gene Expression Profiles 1.0 1.045 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4279 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 SLC41A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57976 GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles 1.0 1.1439 periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26848 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.974684 TCF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19773 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZKSCAN1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3115 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 intermediate stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08612 MAPK13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61472 GSE149264,GSE149267_2_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_2_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null EME2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.54334 hsa-miR-3120-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PTPRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6397 GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.901798 TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE163275_1_v_0_irf8_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TENM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21929 OVOL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2448 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33314 r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9903 C2CD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54406 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MBOAT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36822 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.05882 PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null Leucine-rich repeat InterPro Predicted Protein Domain Annotations 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05067 POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.20027 FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE122215,GSE122217_5_v_2_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IGF2BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12623 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WEY5-0826-SM-4LMIH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 KDM5A ChEA Transcription Factor Targets 1.0 null muscle GTEx Tissue Gene Expression Profiles -1.0 -1.24274 intermediate stratum of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63791 orbital frontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.69252 GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.22178 posteroventral (inferior) parietal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45117 GSE148695,GSE167284_2_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Body mass index x sex x age interaction (4df test) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.5 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELK4 ENCODE Transcription Factor Targets 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE134375_0_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32042 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2428 PCYT1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17615 CPCN CCLE Cell Line Gene CNV Profiles 1.0 2.19473 GTEX-OXRP-2526-SM-2S1NO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XQ8I-1526-SM-4BOOH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 DUSP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2919 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.05446 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100355_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.73775 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00893 AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30565 Perturb_6250_KO_Ago2_SRP041835 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SLC39A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71676 PAX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39549 REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles 1.0 0.837558 REST_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.94987 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.71053 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-2826-SM-46MWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-PX3G-2626-SM-2I3EG GTEx Tissue Sample Gene Expression Profiles 1.0 0.96367 superficial stratum of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43099 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07537 SARS-BatSRBD_0Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.13495 GSE85565_1_v_0_tcf21_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-NFK9-2226-SM-3MJGP GTEx Tissue Sample Gene Expression Profiles 1.0 1.0232 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DAOY CCLE Cell Line Gene CNV Profiles 1.0 1.35061 hek293 HPA Cell Line Gene Expression Profiles -1.0 -1.37019 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null AP2B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.53608 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22274 H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09049 DDIAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06449 RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4263 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 JUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43524 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.68598 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.9468 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.86338 H3K79me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050416 mantle zone of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51381 CAPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.48688 r8 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21318 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCAPD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13215 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.988087 GSE135514_2_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null MXI1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990992 H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiac Troponin-T levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HABP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44053 FLI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A5-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 2.15039 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.878628 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null u266 HPA Cell Line Gene Expression Profiles 1.0 0.974571 fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.47064 TCCSUP COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K79me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNU668 CCLE Cell Line Gene Expression Profiles -1.0 -1.8794 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.74975 p2 portion of the parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41553 RAD21_02_190 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61143 PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95903 GSE158834_11_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE226249_2_v_1_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P44H-0426-SM-2XCEZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-QDVN-2326-SM-2S1PF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZNF85 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19892 MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53258 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.982699 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.03167 ARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26561 GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.06722 POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles 1.0 1.41786 GTEX-WEY5-1526-SM-4LMJF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.97621 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18285 FAHD2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53372 GTEX-RU72-1026-SM-46MUG GTEx Tissue Sample Gene Expression Profiles 1.0 0.873698 FTSJ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14468 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053384 DB DepMap CRISPR Gene Dependency 1.0 9.27261 UROD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.66679 GSE175787_11_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7390-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64374 ZDHHC21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1614 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-0426-SM-33HBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQW-0626-SM-447A6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Msgn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.786 CBX3 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52553 GSE205729,GSE205731_2_v_0_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.86168 NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 1.60962 CREB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24203 smoothmuscle_8c HPA Tissue Sample Gene Expression Profiles -1.0 -1.20123 GTEX-QDVJ-1326-SM-48U1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FOXA2 ENCODE Transcription Factor Targets 1.0 null hsa-miR-590-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 EYA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81224 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19987 KDM6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.48368 POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-0626-SM-4E3HQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.895198 MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Submedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02664 PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 1.01732 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF783 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46874 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.97212 GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.884025 POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPNRTBM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.83611 KAT2A ENCODE Transcription Factor Targets 1.0 null GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XMK1-2226-SM-4B673 GTEx Tissue Sample Gene Expression Profiles 1.0 0.900213 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46301 ETV2::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3782 Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBE2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62849 GTEX-S32W-2026-SM-4AD6E GTEx Tissue Sample Gene Expression Profiles 1.0 0.839898 CEBPB ENCODE Transcription Factor Targets 1.0 null H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.60968 GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66174 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 2.39242 superficial stratum of r9Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35618 GTEX-QDT8-0326-SM-32PL1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE180951_2_v_3_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null TMEM41A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99052 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46324 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85916 CCNT2 ENCODE Transcription Factor Targets 1.0 null ZNF671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42833 disease of mental health GWASdb SNP-Disease Associations 1.0 0.041796 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null LK-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03293 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850714 H3K9ac_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Panhypopituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.188 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60877 GSE172494_3_v_1_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.951149 SP4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 HUP-T4 COSMIC Cell Line Gene Mutation Profiles 1.0 null EMC-BAC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SF3B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41556 dorsolateral prefrontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 GTEX-R3RS-0126-SM-3GIJL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE164508_1_v_0_bortezomib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDAMB134VI CCLE Cell Line Gene Expression Profiles 1.0 1.55328 H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KYSE-270 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.31818 LHX9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04555 A172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23047 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ASGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23004 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.41084 ASB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45848 Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus ambiguus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54228 GTEX-PLZ6-1326-SM-3NB24 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83871 NRF1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S7SF-1826-SM-3K2AD GTEx Tissue Sample Gene Expression Profiles 1.0 0.877248 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PEX19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59018 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-2426-SM-2S1OV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-616 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992846 ZNF410 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.14693 FOXP2 ENCODE Transcription Factor Targets 1.0 null GSE200352_1_v_8_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.12131 GTEX-TKQ1-0226-SM-33HB5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859269 GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CISH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75015 hsa-miR-607 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 DVL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13396 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.61969 chr1_74211942_T_TAAAG_b38 GTEx eQTL 2025 1.0 1.02249 oral mucosa HPA Tissue Protein Expression Profiles -1.0 -0.856547 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0308 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2541 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HHIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85888 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05049 Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5579 Pulvinar TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 KCI-MOH1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.990916 AU565 DepMap CRISPR Gene Dependency 1.0 2.975 LAMB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29957 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.75344 CBX2-27304074-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EGR1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4415-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.844417 Ventral posterior complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10157 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.03901 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-1626-SM-2S1QW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZH-2626-SM-2HMJM GTEx Tissue Sample Gene Expression Profiles 1.0 1.01241 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HINT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80654 H3K56ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6385 C2orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92296 ATP7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47822 POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 0.973815 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null NEK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98222 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zfp36l2_deficiency_GDS3574_153_mouse_E14.5 fetal liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 OE33 DepMap CRISPR Gene Dependency 1.0 2.52896 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05049 GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12599 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35404 SLC37A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37905 ALAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41751 GSE221633_0_v_1_trim24_human RummaGEO Gene Perturbation Signatures -1.0 null PPIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29342 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.83412 chr1_74206790_G_A_b38 GTEx eQTL 2025 1.0 2.45593 PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06215 CHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67937 1321N1 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 KYAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30474 TOLLIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2887 NDUFB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75053 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null M6PR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98764 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SEPTIN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9302 WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89614 amygdaloid complex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.25114 GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7996-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CPSF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39563 MRPL20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19744 WM115 DepMap CRISPR Gene Dependency 1.0 2.55909 GSE241031_0_v_4_abemaciclib_human RummaGEO Drug Perturbation Signatures -1.0 null HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12832 H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null smallintestine_4b HPA Tissue Sample Gene Expression Profiles -1.0 -0.985717 GTEX-N7MT-0126-SM-2D7VT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null SARS-CoV_96Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.70751 H3K4me1_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null medial pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35661 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-1126-SM-4LMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04715 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.259 PHF8 ChEA Transcription Factor Targets 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5035 HSD17B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56283 LARP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94568 FADU CCLE Cell Line Gene Expression Profiles 1.0 1.6802 HES4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60752 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.611 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 hsa-miR-3129-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.29787 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE146894_3_v_8_hira_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE104508_0_v_3_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38663 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr1_74207657_C_T_b38 GTEx eQTL 2025 1.0 3.31292 PRDM16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18467 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07643 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.22027 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO320 DepMap CRISPR Gene Dependency 1.0 2.83508 r8 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01684 GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916311 H3K79me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null terminal nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04869 SAOS-2 COSMIC Cell Line Gene CNV Profiles 1.0 2.1316 GTEX-XXEK-0926-SM-4BRWH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE87862_0_v_1_mov10_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNAPIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38096 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 r8 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42976 UBALD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87046 TCF7L2_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSTB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.42776 MAPKAPK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81041 GSE221633_3_v_1_trim24_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.30099 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.403 GSE231648_1_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-PWN1-2026-SM-48TD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 lower basal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10831 GSE231648_0_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29272 GBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.53243 GTEX-WK11-0626-SM-3NMAV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.06171 esr1_21713035_mcf7_lof_human_gpl570_gds4061 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.141464 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.70769 IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE215351,GSE215794_2_v_3_kdm8_mouse RummaGEO Gene Perturbation Signatures 1.0 null W chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.826 YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4236 ZNG1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78622 Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.404 RPMI 2650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00893 mcf7 HPA Cell Line Gene Expression Profiles -1.0 -2.27486 UPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2626 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.54713 H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21984 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.974161 CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 E2F6 ENCODE Transcription Factor Targets 1.0 null ZNF622_02_108 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59061 GATB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72717 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Retrosplenial area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17951 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.5326 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R53T-1526-SM-48FEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.34974 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE209680,GSE209683_0_v_1_nfat5_mouse RummaGEO Gene Perturbation Signatures -1.0 null TCF12_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Testicular cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.865 POLR2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98278 hsa-miR-4288 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 PPP1R7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16213 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YV-1826-SM-2YUNI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.105208 HJURP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30918 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLI1_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 RBM45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44276 MDST8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916013 PDE10A_KO_GSE40377_581_mouse_Striatum and hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TANGO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 GTEX-U3ZN-2626-SM-3DB7T GTEx Tissue Sample Gene Expression Profiles 1.0 1.28667 GTEX-QDVN-0926-SM-2I5GL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08376 GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1586 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS6KA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96038 GTEX-OXRP-0226-SM-3NB14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21324 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65925 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.955298 CDX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3723 GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles 1.0 1.01427 PDK1_knockout_80_GSE26290 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.78479 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.5816 ETV6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.234 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.923297 GTF2B ENCODE Transcription Factor Targets 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06687 GBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9321 FOXF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.697 KMS20 CCLE Cell Line Gene CNV Profiles -1.0 -1.51452 POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 GTEX-UTHO-1026-SM-3GAF7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39415 POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null H3K27ac_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RASSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03654 AEBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82601 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bed nuclei of the stria terminalis, anterior division, ventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21723 IPC298 CCLE Cell Line Gene CNV Profiles 1.0 2.0087 EDEM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36973 XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05589 ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nuclear exosome targeting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.707 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 2.03605 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RU72-0326-SM-2TF5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.461606 GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17177 GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SLC39A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64556 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATF2 ENCODE Transcription Factor Targets 1.0 null GSE168676_2_v_3_dach1_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-N417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00793 Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null B4GALNT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1503 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-0126-SM-3NB1E GTEx Tissue Sample Gene Expression Profiles 1.0 0.955871 Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46301 SAP30 ENCODE Transcription Factor Targets 1.0 null UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9136 HCC78 CCLE Cell Line Gene CNV Profiles 1.0 1.58782 CD4_Memory_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.932246 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FOSL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.913 GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZFYVE26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.452 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28824 GSE62292,GSE62295_2_v_0_col4a3_mouse RummaGEO Gene Perturbation Signatures -1.0 null COPS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00017 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE174498,GSE174500_2_v_7_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null NLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51904 GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02647 layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36507 NID1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2043 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.62418 LAG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88305 GTEX-TSE9-0126-SM-3DB83 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.958562 VEGFA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38241 Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9 Rummagene Transcription Factor Associations 2026 1.0 null EGR1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45645 TRPM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.84564 DDX49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57867 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.85917 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.847048 SUM 229PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885523 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 1.08583 GTEX-TMMY-1226-SM-4DXT6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0742 DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.990916 adrenal gland GTEx Tissue Gene Expression Profiles 1.0 1.12081 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51903 HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.08932 POU2F2_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.78034 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLA2G3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94368 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 MOTN1 CCLE Cell Line Gene Expression Profiles 1.0 1.3825 GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.845765 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.97502 GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Activin AB complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.535 USP24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02449 Retrosplenial area, ventral part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00025 H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4446-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 GTEX-QCQG-2026-SM-2S1PH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32058 Liver Neoplasms CTD Gene-Disease Associations 1.0 1.35415 GTEX-OIZI-0008-SM-2XCFD GTEx Tissue Sample Gene Expression Profiles 1.0 0.936616 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.903341 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86021 G121 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07409 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.884442 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00246 GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.0784 Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62167 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34511 MLH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72213 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.876028 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69281 GTEX-TML8-2026-SM-32QOP GTEx Tissue Sample Gene Expression Profiles 1.0 1.26832 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902128 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.26632 GSE202434,GSE202438_6_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QDT8-1026-SM-43V6X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP Rummagene Transcription Factor Associations 2026 1.0 null NBPF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75641 ZC3H12D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.61274 RNF114 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05461 COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.62118 EGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13821 PSN1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.11768 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.881889 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OSC-20 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02566 GTEX-S3XE-1726-SM-3K2AM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SNU1033 CCLE Cell Line Gene CNV Profiles 1.0 2.59009 CAMTA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47344 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.885523 MRPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4796 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51011 intermediate stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5287 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE193258,GSE193259_9_v_3_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1536 ACSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61999 EBF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.64069 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38885 GATA6-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null inner CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24715 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.992846 GTEX-XV7Q-2626-SM-4BRVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.1243 Meiotic prophase fetal germ cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null PDHX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00014 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.65484 KDM5B ENCODE Transcription Factor Targets 1.0 null PDCL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42721 NOTCH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.191 GTEX-XMK1-1126-SM-4IHJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24487 cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15777 mantle zone of r8Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06049 CTBP1-25329375-LNCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-XQ8I-1826-SM-4BOOJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-T2IS-0226-SM-32QPH GTEx Tissue Sample Gene Expression Profiles 1.0 1.15869 NFIX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77601 GTEX-XV7Q-1726-SM-4BRUU GTEx Tissue Sample Gene Expression Profiles 1.0 1.3389 C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 COLO668 CCLE Cell Line Gene CNV Profiles 1.0 1.42653 GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18852 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49797 PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.4691 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.0449 GTEX-UJMC-0226-SM-4IHLH GTEx Tissue Sample Gene Expression Profiles 1.0 1.1624 ZNF677 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3555 Infralimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.507 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.71742 GSE211262,GSE211263_3_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22 Rummagene Transcription Factor Associations 2026 1.0 null RB1CC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15883 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDELR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61001 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FADU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28101 Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23494 POLR2A_K562_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5649 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the mouth GWASdb SNP-Phenotype Associations 1.0 0.147074 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IFIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15877 GTEX-VUSG-2626-SM-4KKZI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 JAG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46492 HL-60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.31689 Grm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.597 PDLIM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01665 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80926 MAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43065 SMNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21312 SLC27A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83132 THAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31942 EGR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97852 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27074 mantle zone of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17732 TGDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04026 MINK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61536 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CFLAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26602 BCLAF1 ENCODE Transcription Factor Targets 1.0 null skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 GTEX-SE5C-2126-SM-4BRUJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.861139 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectal benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -0.856547 H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.23979 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10699 16912175-SuppTable3b GeneSigDB Published Gene Signatures 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.50689 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.18482 GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles 1.0 0.997427 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-WFG7-1026-SM-4LMK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null C16orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92705 SKMEL30 DepMap CRISPR Gene Dependency 1.0 2.03557 ACTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54897 H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18061 retromammillary area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12459 MRAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34314 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06624 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927746 RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE128076_2_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54403 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877963 ARPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60528 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.0701 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.74358 Nicotine dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.31 PTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.87933 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4701 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10818 SLC36A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52012 Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.66036 MAP6D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72398 FAM104B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93448 mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.59284 H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.52863 r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34891 GTEX-S32W-2526-SM-2XCB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Egg TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.456 internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00533 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REXO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4678 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70441 orbital frontal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850714 CAMA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50446 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZC3HC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84653 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.75792 C1orf122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16837 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.5556 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null DNAJB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62685 NCIH226 DepMap CRISPR Gene Dependency 1.0 2.40213 NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71665 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.274 ADCK5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8061 GTEX-U3ZG-0001-SM-47JYF GTEx Tissue Sample Gene Expression Profiles 1.0 0.99262 UQCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.401 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null XRN2 ChEA Transcription Factor Targets 1.0 null GTF2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, ventral part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77002 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2878 TIMMDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81629 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75274 anterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.856966 GTEX-QXCU-0626-SM-2TC69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11927 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06069 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 dorsolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.910017 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22549 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.39869 inner CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.965202 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.543 disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.970997 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF311 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.98915 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1737 PER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52683 RCOR1 ENCODE Transcription Factor Targets 1.0 null PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17717 GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.22707 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-632 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6087 Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76151 ATP6V1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16424 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-175-VII Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49797 LEO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.40397 YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OSC19 DepMap CRISPR Gene Dependency 1.0 2.15456 Migraine GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.969897 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAP47 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25281 RUNX3 ENCODE Transcription Factor Targets 1.0 null GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.22449 GTEX-RTLS-0226-SM-2TF5E GTEx Tissue Sample Gene Expression Profiles 1.0 0.84811 IQ motif, EF-hand binding site InterPro Predicted Protein Domain Annotations 1.0 null NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.916013 HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.33631 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.880146 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ERCC6L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.68397 inner SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10799 NFATC1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4U-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF367 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55612 inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.76151 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HEXIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78658 GSE190235_1_v_2_foxo3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NPIPA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75638 Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ANKRD13C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55664 Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07537 Rosacea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.05 TNPO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86957 KDM5A ENCODE Transcription Factor Targets 1.0 null PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB Rummagene Transcription Factor Associations 2026 1.0 null BATF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24479 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.3882 GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.15146 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2216 PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null Mobilized_CD34_Primary_Cells_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.915925 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23497 TRIM28_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.36337 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PRDM7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27411 CDK13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38622 EGR1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null C-33-A COSMIC Cell Line Gene Mutation Profiles 1.0 null Inferior temporal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.524 Alcohol dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.058 PIERCE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16973 GSE206984_1_v_0_bortezomib_human RummaGEO Drug Perturbation Signatures 1.0 null TNFRSF10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.98354 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles 1.0 0.972544 vascular disease GWASdb SNP-Disease Associations 1.0 0.090919 NDUFA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29155 GSE158834_11_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82488 496100614_PCx_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.32664 RBBP5 ENCODE Transcription Factor Targets 1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF7L2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7202 VAV2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45258 mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.95329 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CDX2-21074721-CACO-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Dendritic spine head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.852 FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RWDD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11247 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELMO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51616 BRD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37994 H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-548z TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A6MB-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOSL2 ENCODE Transcription Factor Targets 1.0 null MOV10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80999 HDGFL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45667 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null STAT5_01_279 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.50222 PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK1_unique_ELK1 Rummagene Transcription Factor Associations 2026 1.0 null GDF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6957 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BTBD18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.71501 POLR2A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACCMESO1 CCLE Cell Line Gene Expression Profiles 1.0 2.30164 FOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47277 HMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57361 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_6_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null RAB11FIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.441 MDA-MB-330 COSMIC Cell Line Gene CNV Profiles -1.0 -3.06578 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles 1.0 0.923361 TPGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41749 G141 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0778 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7931 AGO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77238 Nucleus of the brachium of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22098 GARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70342 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.68041 Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23252 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM83E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85374 HDAC1 ENCODE Transcription Factor Targets 1.0 null OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00578 GTEX-R55F-0126-SM-48FCK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 central portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22827 r7 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6122 Retrosplenial area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88403 M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.908654 RHOT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26284 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Plasma membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.774 MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9212 ZC3H11A ENCODE Transcription Factor Targets 1.0 null GSE250534_0_v_3_cabergoline_mouse RummaGEO Drug Perturbation Signatures 1.0 null H2BK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02322 GTEX-WYJK-1026-SM-3NM8W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CETN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00945 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27293 GTEX-VJYA-1226-SM-3GIJ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03533 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67576 abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.092375 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PXMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05473 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NFYA-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.880146 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arteriosclerosis GWASdb SNP-Disease Associations 1.0 0.400489 GSE148657_2_v_1_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11863 ELF1 ENCODE Transcription Factor Targets 1.0 null layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.980343 MAD2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43583 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-X4XY-0226-SM-4E3IZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.13523 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23232 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SYT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60114 TAF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE193258,GSE193259_9_v_0_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Schizophrenia GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1699 ONECUT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38701 GTEX-UPK5-0003-SM-3NMDI GTEx Tissue Sample Gene Expression Profiles 1.0 1.11094 Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0062 ZNF669 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.285 AR ChEA Transcription Factor Targets 1.0 null MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08002 KP3 CCLE Cell Line Gene Expression Profiles 1.0 1.3821 MFE319 CCLE Cell Line Gene CNV Profiles 1.0 2.11644 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 substance dependence GWASdb SNP-Disease Associations 1.0 0.210092 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.10952 GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OC-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00486 PCI30 DepMap CRISPR Gene Dependency 1.0 3.56229 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.99779 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42685 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.880146 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91538 GRIN2D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37446 KDM4A ENCODE Transcription Factor Targets 1.0 null PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-WRHU-0326-SM-3MJFY GTEx Tissue Sample Gene Expression Profiles 1.0 0.878151 NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1753 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.27241 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.868529 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4639-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 CALCOCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.3777 parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.966238 LINGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02378 GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null transient Purkinje cell clusters Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03736 ENTPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26604 ZNF620 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9974 SRR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70806 H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC30A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.43313 GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null RAD21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9756 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.831522 PI4KA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26115 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAB3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.81549 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13204 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null oral cleft GWASdb SNP-Phenotype Associations 1.0 0.588029 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.3552 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4277 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.932252 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EBC1 CCLE Cell Line Gene Expression Profiles 1.0 1.83347 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05243 SLC17A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5645 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RU72-0926-SM-2TF6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-WXYG-2026-SM-4E3IY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13583 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.985437 WDTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.52389 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 U-118-MG COSMIC Cell Line Gene CNV Profiles -1.0 -3.06578 GTEX-TMMY-1726-SM-4DXTD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 LS1034 DepMap CRISPR Gene Dependency 1.0 3.34955 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.37339 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.955294 PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null NFATC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.10041 GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.85801 GSE178714_5_v_2_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null ARHGAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.89471 GTEX-U8T8-2326-SM-3DB96 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834081 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.997899 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null YY1-26981420-C2C12-MOUSE-MUSCLE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.45716 GSE247775_1_v_0_tmprss2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P4PP-0126-SM-3LK69 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5276 GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27781 MYO19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38189 Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr1_74219556_T_C_b38 GTEx eQTL 2025 1.0 1.14205 SATB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2672 PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR Rummagene Transcription Factor Associations 2026 1.0 null DMAC2L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28399 SFT2D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06281 Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.36268 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 38.0 ventrolateral prefrontal cortex_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.59284 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null alcohol dependence GWASdb SNP-Disease Associations 1.0 0.541364 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.824929 HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IC-21 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.858 H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.236 membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.74728 KYAE1 DepMap CRISPR Gene Dependency 1.0 3.14842 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 IPMK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.28509 A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.864183 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06185 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10645 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.144 SW900 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08548 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles 1.0 0.911036 TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_10_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null SFPI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EFO-21 COSMIC Cell Line Gene Mutation Profiles 1.0 null ventromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03395 CHURC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65349 GTEX-XQ8I-2326-SM-4BOQC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 0.874361 GSE103003_1_v_0_zeb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Body mass index (age <50) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.45229 HES7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51707 NFKBIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28047 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane LOCATE Predicted Protein Localization Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCAS COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UPIC-1626-SM-4IHKT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GPR137 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13819 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mantle zone of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45776 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.25387 H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null outer CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.868142 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02095 Prelimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41394 snRNA-activating protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.023 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.36749 Tapetum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.05945 NB13 DepMap CRISPR Gene Dependency 1.0 2.50761 TSPAN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.75252 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Thap11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.0758 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.778318 Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null u138mg HPA Cell Line Gene Expression Profiles -1.0 -0.873106 Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1776 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null HS 839.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.92764 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 MCTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49044 FOXM1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35661 ATG4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28079 Microgametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.735 SOSS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.055 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZNF805 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05047 Mammillary body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34079 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.948853 Sigmoid_Colon Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.05496 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prostate HPA Tissue Protein Expression Profiles 1.0 1.5547 TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0126-SM-4AD6S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CLN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.12741 COA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10489 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34184 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25309 ARID3A ENCODE Transcription Factor Targets 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRSF9_02_90 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60768 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.095 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ5-0326-SM-3P614 GTEx Tissue Sample Gene Expression Profiles 1.0 0.896172 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.81297 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 MYH10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69273 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13494 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4564 intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07893 NCIH520 CCLE Cell Line Gene Expression Profiles -1.0 -1.52023 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SNU-601 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06215 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Smoking initiation (ever regular vs never regular) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.739794 MARK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19005 outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99169 TCF7L2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.996809 chr1_74206639_C_A_b38 GTEx eQTL 2025 1.0 1.87772 Posterolateral visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16544 PK45H CCLE Cell Line Gene CNV Profiles -1.0 -1.75244 TP53-18474530-U2OS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1 Rummagene Transcription Factor Associations 2026 1.0 null JARID1A-20064375-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 0.912729 TMEM168 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.966 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null PRRC2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37507 ZSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44421 JHOS2 CCLE Cell Line Gene CNV Profiles 1.0 1.34821 NRF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.05838 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06271 hsa-miR-4291 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.76705 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.03654 Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TDRD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9205 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05264 SPPL2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38771 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.405 SOX2 ChEA Transcription Factor Targets 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-584 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-WYVS-1626-SM-3NM9R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 superficial stratum of r7Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81765 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures -1.0 null DCAKD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12397 CAPN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53962 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05656 GSE136622_0_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE229344_1_v_0_cyb5r3_human RummaGEO Gene Perturbation Signatures -1.0 null lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28774 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.81519 FLI1 ChEA Transcription Factor Targets 1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRL-0126-SM-2YUMP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE232558_0_v_1_fbxl12_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.11967 hsa-miR-4507 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null binding GO Molecular Function Annotations 2015 1.0 null dentate (lateral) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43097 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XGQ4-0926-SM-4AT4U GTEx Tissue Sample Gene Expression Profiles 1.0 1.09847 GSE140997_2_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.35749 GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.957675 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00234 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.70688 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051514 lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06367 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05916 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3175 LRRC41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47236 Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.877321 MAP3K7_knockout_246_GSE34417 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.58142 LYN Pathway Commons Protein-Protein Interactions 1.0 null GSE157233_2_v_4_a1cf_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r10 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04596 icSARS CoV_36Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.22883 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMURF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90719 STAT3 ChEA Transcription Factor Targets 1.0 null NCCIT COSMIC Cell Line Gene Mutation Profiles 1.0 null OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null GTPBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21053 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.397 H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4144 RRM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08787 16818684-Table2b GeneSigDB Published Gene Signatures 1.0 null CREM ChEA Transcription Factor Targets 1.0 null TEAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19585 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25663 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ETV2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3638 chr1_74208492_A_G_b38 GTEx eQTL 2025 1.0 1.42823 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23047 GTEX-XYKS-0926-SM-4BRVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.08721 HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.826841 MTMR6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.56611 PXYLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07376 H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.05271 GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.31004 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WYVS-2126-SM-3NMA3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HO-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GNAO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49127 GTEX-QCQG-1726-SM-3GIJ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.20696 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-1626-SM-48TCQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.832797 GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE158834_10_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r8Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56424 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3804 H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20994 ANKRD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59421 OGT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74179 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02319 Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35561 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.954416 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 External side of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.341 ZSCAN16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17905 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterodorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51747 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SPI1 ENCODE Transcription Factor Targets 1.0 null PK-59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.1449 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6474 cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.3639 SNU-182 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37028 HLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21211 H2BC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51152 TAL1 ENCODE Transcription Factor Targets 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-5511-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKRD39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32869 GTEX-OHPK-1326-SM-3MJGN GTEx Tissue Sample Gene Expression Profiles 1.0 1.24209 FEM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62015 SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 P300-27058665-CHIP-SEQ-ZR-75-30CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.827 GTEX-T2IS-0008-SM-4DM75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862584 core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70441 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-V955-0326-SM-4JBGV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 DMS 79 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.837275 striohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78147 suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11333 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW837 CCLE Cell Line Gene CNV Profiles -1.0 -1.55351 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.96343 TSEN54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29179 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.826136 NDRG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.89037 inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0003 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GSE151494_8_v_3_nrp1_mouse RummaGEO Gene Perturbation Signatures 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06185 Anxiety GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.804576 peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.51573 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.71683 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83658 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53-18474530-U2OS-human ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 0.864845 NCI-H716 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.383 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10758 GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231648_4_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Bipolar disorder and schizophrenia GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.509691 ARID4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80302 septodiagonal transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46637 intermediate stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48678 ADAMTSL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8055 TREX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.90668 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE220806_1_v_3_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33332 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BTN2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36976 EB1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04498 MN-60 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null p1 part of the pararubral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15786 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09588 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.72593 H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SE5C-0726-SM-4BRWY GTEx Tissue Sample Gene Expression Profiles 1.0 0.960352 GTEX-QEG4-0226-SM-2S1PY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZDHHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1127 layer IIIb of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7304 GTEX-WCDI-0002-SM-3P61U GTEx Tissue Sample Gene Expression Profiles 1.0 1.31239 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 786-O Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.837449 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02323 H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.25525 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28824 Substance dependence DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.162 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07801 GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CHAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96183 ACADSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11424 HROB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46146 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.73379 GSE140651,GSE140653_2_v_4_med1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null nod2_21335489_hek293_lof_human_gpl570_gds4416 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.042384 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.54743 PECAPJ49 CCLE Cell Line Gene Expression Profiles 1.0 1.35657 H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null H3K79me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2561 NRF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UTP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32623 ESCO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61561 retromammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20373 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.85262 cell periphery COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7732 H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6478-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRPS11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73279 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75857 GTEX-S341-1726-SM-3K2AK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE162623_0_v_1_ezh2_human RummaGEO Gene Perturbation Signatures 1.0 null CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7594-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC106 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85516 ZNF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48994 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.947 KAT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83845 POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.786 Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE85880,GSE85881_0_v_1_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837498 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.44063 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 2.13011 Chiasma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 ZMIZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88252 HOXB13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94011 RPS6KA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92104 GTEX-SN8G-0326-SM-32PLG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52783 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4094 RPIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01841 TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TSPAN9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.18793 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GGA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13346 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85753 COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14972 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50185 H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RBM14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71002 GSE219195_1_v_3_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null VN(H5N1)_12hour_None_GSE37245 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.86373 SMC3 ENCODE Transcription Factor Targets 1.0 null EPB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53089 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.37071 superficial stratum of Ist Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15378 MDAMB436 CCLE Cell Line Gene CNV Profiles 1.0 1.77603 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.82745 GSE163862_2_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null TNFRSF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.14386 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.876709 SIN3A ENCODE Transcription Factor Targets 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCK81 DepMap CRISPR Gene Dependency 1.0 3.03679 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fatty Liver CTD Gene-Disease Associations 1.0 1.09366 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.38105 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.37292 SLC8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5781 Laterodorsal thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.582 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.68574 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.22365 hsa-miR-548c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Occipital pole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.93845 CENPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73286 Cystic Fibrosis_Lung_GSE3100 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.68454 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null KMT5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68155 TP53RK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03689 TP63 ChEA Transcription Factor Targets 1.0 null MGST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16171 SIHA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.28092 NRF1 ENCODE Transcription Factor Targets 1.0 null GSX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10673 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.880146 DU4475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.70931 PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null FHIP1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46976 DMS79 CCLE Cell Line Gene CNV Profiles 1.0 3.27943 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null red nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13791 Spinal nucleus of the trigeminal, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13326 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.40568 GTEX-XV7Q-2326-SM-4BRVZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.35615 GSE205729,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null Smoking status (ever vs never smokers) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0699 GSE244518,GSE244520_1_v_0_dnmt3b_human RummaGEO Gene Perturbation Signatures 1.0 null FARAGE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02339 hsa-miR-4680-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75271 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28196 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null VPS26A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44943 GTEX-X4XY-0826-SM-4E3JM GTEx Tissue Sample Gene Expression Profiles 1.0 0.945067 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TMZS-0126-SM-3DB9Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-1526-SM-4IHLU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NBEAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3675 Bed nuclei of the stria terminalis, posterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89452 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89264 H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UOK101 DepMap CRISPR Gene Dependency 1.0 4.04048 G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.45191 hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14922 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.15815 RPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82686 bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -0.909595 GSE223008_7_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Intestinal cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.202 POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55627 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4QT-0126-SM-2I3FL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NCI-H378 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.92602 Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSK3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34178 KLHL36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94564 HINFP_02_36 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.64452 PRB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17076 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.49847 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.286026 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.87652 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.99811 TMEM86A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31676 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850714 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99133 VWDE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.586 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -0.856547 H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lower basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17732 GSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30229 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null skin HPA Tissue Gene Expression Profiles -1.0 -0.864386 GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE129293_0_v_1_chd4_human RummaGEO Gene Perturbation Signatures 1.0 null ARH77 DepMap CRISPR Gene Dependency 1.0 3.08 c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.98439 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6048 SRY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6786 NCI-H250 COSMIC Cell Line Gene CNV Profiles -1.0 -3.06578 GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles 1.0 0.903389 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS153 CCLE Cell Line Gene Expression Profiles 1.0 1.47534 H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null paclitaxel_homo sapiens_gpl570_gse39042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1648 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE163862_0_v_3_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null fibroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22415 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TMEM79 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65725 H3K27ac_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LU-134-A COSMIC Cell Line Gene Mutation Profiles 1.0 null ChIP_JARID1A_20064375 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S3XE-0126-SM-4AD4R GTEx Tissue Sample Gene Expression Profiles 1.0 0.975566 HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32344 KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.928533 GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TGW COSMIC Cell Line Gene Mutation Profiles 1.0 null BECN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10751 HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OTUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63499 MSANTD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9282 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.74348 GTEX-P4QS-1326-SM-3NMCD GTEx Tissue Sample Gene Expression Profiles 1.0 0.854179 PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_all_ELK1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THAP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54927 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949401 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null upper basal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05528 NCIH1915 CCLE Cell Line Gene Expression Profiles 1.0 1.97055 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P31-FUJ COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null lower dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18836 mammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20261 A549 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.20259 GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Foxn1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.6938 DIFI DepMap CRISPR Gene Dependency 1.0 10.1867 DIP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19186 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46637 GTEX-T2YK-2226-SM-32QPT GTEx Tissue Sample Gene Expression Profiles 1.0 0.859048 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53326 HCFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.14239 SIG-M5 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 LYRM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26797 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mesocorticolimbic dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.604 Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KYSE220 DepMap CRISPR Gene Dependency 1.0 11.3168 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07071 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NFK9-0226-SM-2HMKQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 YAPC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.92926 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.12539 SNU738 CCLE Cell Line Gene CNV Profiles 1.0 1.66878 ZBTB7A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.6727 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.966599 r8 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.087 FOXD4L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11486 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOP53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5078 H3K79me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4681 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCL1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.26253 HCC2108 CCLE Cell Line Gene Expression Profiles 1.0 1.47172 PPP1R15B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39962 NOP56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01203 GSE193282_3_v_1_cd44_mouse RummaGEO Gene Perturbation Signatures 1.0 null RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IFT46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96252 RELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32824 Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.716 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cell periphery COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.774 RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE149264,GSE149267_9_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE196671_6_v_1_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U3-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELAVL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71096 H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DCLRE1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81953 SBC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null H4C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58293 GOSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0652 DNAJA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17312 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PSMF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27159 H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.892947 PRMT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66408 hsa-miR-323b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.910516 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02064 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.269 PLCG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1979 GTEX-N7MS-1626-SM-3LK5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.18407 GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 0.858722 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852035 GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.952403 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOGGUVW CCLE Cell Line Gene Expression Profiles 1.0 1.39701 hsa-miR-205 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null all GWASdb SNP-Phenotype Associations 1.0 0.034358 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PX3G-0226-SM-3NB2C GTEx Tissue Sample Gene Expression Profiles 1.0 0.84044 GTEX-S32W-0126-SM-4AD61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07485 YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.28287 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.894181 PLPP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46097 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29D-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12225 GSE231648_0_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PINX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46738 STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21866 YY1_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63766 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S341-0126-SM-4AD64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03418 FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GLIS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72783 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.93945 TSHZ3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83656 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 0.89501 DPY30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28789 PTPRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45267 SKNBE2 CCLE Cell Line Gene CNV Profiles -1.0 -1.57217 GTEX-WHSE-0126-SM-3NMBT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MXI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.24138 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XXEK-0726-SM-4BRWF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 LMBR1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28878 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD4L6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23118 NCI-H1703 COSMIC Cell Line Gene Mutation Profiles 1.0 null thyroid_5b HPA Tissue Sample Gene Expression Profiles 1.0 0.965104 G122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22008 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PPIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05138 RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1226-SM-2XCFP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10194 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-4941-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.88248 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3118 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE115542_2_v_1_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-607 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSEN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88989 MAML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24835 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0011-R9A-SM-32PLV GTEx Tissue Sample Gene Expression Profiles 1.0 0.922494 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02095 OVSAHO CCLE Cell Line Gene CNV Profiles 1.0 1.76224 GSE160373_6_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-0926-SM-4BOPI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 L-Wnt-3A cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.109 GSE211262,GSE211263_2_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27015 H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MEF2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null REST ChEA Transcription Factor Targets 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.0629 GTEX-R55G-0926-SM-48FDN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SNU840 CCLE Cell Line Gene CNV Profiles 1.0 1.66643 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CCNT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12275 PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null EPHX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38867 STK17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86404 GIGYF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.41535 hsa-miR-499a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE140997_10_v_7_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XQ3S-0526-SM-4BOQA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MDAMB175VII CCLE Cell Line Gene CNV Profiles -1.0 -1.43011 perimammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17838 GTEX-QLQ7-1926-SM-2S1R6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07606 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13384 chr1_74198130_C_G_b38 GTEx eQTL 2025 1.0 2.847 Roe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.408 cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.73505 anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.873503 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.34428 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.69379 artery disease GWASdb SNP-Disease Associations 1.0 0.126332 RMND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51445 island of Calleja major Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12864 DK-MG COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 2.19321 disease GWASdb SNP-Disease Associations 1.0 0.031211 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84888 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 intermediate stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12356 H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null AQP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68371 H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10529 H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42859 perimammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51191 GTEX-PWOO-2326-SM-2S1PQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Melanoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.784 ATXN7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44808 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TC138 DepMap CRISPR Gene Dependency 1.0 3.42638 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null liminal part of the r7 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10114 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934325 GSE183251_7_v_3_cyp2c70_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GFI1B-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null septopallidal shell area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11535 MYBL2 ENCODE Transcription Factor Targets 1.0 null GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.968607 superficial stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58457 ZNF600 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50583 POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TARBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.77044 IST-SL1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.86834 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1268 Hepatomegaly CTD Gene-Disease Associations 1.0 1.12838 GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72059 superficial stratum of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89376 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTAGE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28184 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5639-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTV1DM DepMap CRISPR Gene Dependency 1.0 2.48644 GTEX-RWSA-0226-SM-2XCBA GTEx Tissue Sample Gene Expression Profiles 1.0 0.981349 TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32369 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61917 OXA1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32198 SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ATF6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15416 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52199 anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.0492 RHBDD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52346 Basolateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.156 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EN COSMIC Cell Line Gene Mutation Profiles 1.0 null MAPK8IP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51938 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15249 Lung squamous cell carcinoma_LUSC_TCGA-43-6770-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ETV4_01_356 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.5972 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17267 HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08548 hsa-miR-1265 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HELA Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.980927 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.3036 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE149901_2_v_0_anlotinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE241031_0_v_2_abemaciclib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5863 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55106 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.39632 PHF8-20622853-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ZW10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23988 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null area postrema Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.79857 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Nucleus ambiguus, dorsal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34806 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JEKO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0778 TMEM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07691 septopallidal transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0303 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975059 DUSP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17798 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.08245 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-494 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 SLC26A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24608 HTATIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.8938 GTEX-XQ3S-1526-SM-4BOOC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SPI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of SePal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03122 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spear TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.719 EJM CCLE Cell Line Gene Expression Profiles 1.0 1.3731 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVN-1126-SM-48TZ7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51011 H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebrospinal AB1-42 levels in normal cognition GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.604576 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89264 PATU8988S CCLE Cell Line Gene Expression Profiles -1.0 -1.55377 DNPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93831 GTEX-P44H-0526-SM-2XCF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-XUZC-1526-SM-4BRV4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null ZC3H10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76665 KIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24426 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.862577 CSRNP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34949 hsa-miR-2964a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 MICOS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90259 CCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28808 NCIH510 CCLE Cell Line Gene Expression Profiles 1.0 2.44568 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.831761 POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1993 DepMap CRISPR Gene Dependency 1.0 2.93 GTEX-Q2AH-0126-SM-48U2B GTEx Tissue Sample Gene Expression Profiles 1.0 0.92414 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.40277 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04956 Rennet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.863 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.7437 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF296 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63157 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10699 GSE207914_5_v_6_nudt7_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18148 H3K4me1_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04261 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49041 ZRANB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39771 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21404 NCIH1755 CCLE Cell Line Gene CNV Profiles -1.0 -2.24774 GTEX-OHPM-2626-SM-33HC5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.842793 primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852035 POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8425-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tonsil HPA Tissue Protein Expression Profiles -1.0 -0.856547 H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.982291 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06215 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null RCOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73592 SFPI1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GDF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32282 hsa-miR-3180-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 205 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975059 fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TML8-0008-SM-4DXUI GTEx Tissue Sample Gene Expression Profiles 1.0 1.02652 SERPINB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98646 GSE183251_1_v_5_cyp2c70_mouse RummaGEO Gene Perturbation Signatures -1.0 null PAK6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13253 OTULIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99736 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PLAAT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65541 GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 1.10523 MYC ENCODE Transcription Factor Targets 1.0 null smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.854083 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FOSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4719 PHETA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99854 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMC-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.69402 GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, nose, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06367 JARID1A-20064375-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE128076_2_v_3_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LCN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07215 NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.53285 KCNC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08389 PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spi1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 71.9347 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X261-0326-SM-3NMD4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMES1 CCLE Cell Line Gene Expression Profiles 1.0 1.60635 NRF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DLG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88401 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST ENCODE Transcription Factor Targets 1.0 null Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29755 CEBPD-23245923-MEF-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15777 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01416 GSE196671_5_v_0_obox4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-TKQ2-0226-SM-4DM6V GTEx Tissue Sample Gene Expression Profiles 1.0 0.953616 MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null FOXO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5828 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7385-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.16432 H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-0426-SM-32PKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.53634 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.844 GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE234340_3_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ROCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.2729 Pancreas Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.23128 MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE188870,GSE188871_0_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null Esophagus Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.959935 NR3C2-34362910-WISTARRAT-HIPPOCAMPUS ChEA Transcription Factor Targets 2022 1.0 null HCC78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48568 PTGFRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26532 Inhibin A complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.565 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00468 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H0-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82447 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.827127 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07104 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.20364 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HF-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterolateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08524 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8712 GTEX-T2IS-0626-SM-32QP6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.21973 Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50094 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146962_0_v_1_glucosamine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null rectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.676172 HCT116 DepMap CRISPR Gene Dependency 1.0 5.25731 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1084 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOS3 CCLE Cell Line Gene CNV Profiles -1.0 -1.34549 PPP1R37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60803 superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.90205 GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-QDVJ-1926-SM-2S1PJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 RFX5 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-302f TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GTEX-V1D1-0626-SM-4JBHN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K79me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21569 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A2-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null centromedian nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03011 GTEX-UTHO-1826-SM-3GAFE GTEx Tissue Sample Gene Expression Profiles 1.0 1.19417 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.2034 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.943088 GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE114690_2_v_3_tnfsf14_mouse RummaGEO Gene Perturbation Signatures 1.0 null RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3575 CBX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87273 GNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50999 PPP1R17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27054 GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.16531 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.920082 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.90806 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975059 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.956073 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.89685 TP53-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null physical disorder GWASdb SNP-Disease Associations 1.0 0.373337 NDUFS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93259 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25102 LS123 DepMap CRISPR Gene Dependency 1.0 3.3778 Olfactory placode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.507 GSE174735_1_v_3_il22_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 5 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34754 salivary gland HPA Tissue Protein Expression Profiles 1.0 1.5547 RIPOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08263 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.58177 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FCSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56702 hsa-miR-548ac TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.273 C3orf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80225 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22243 POLR2A_K562_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles -1.0 -1.85091 GTEX-WFON-1826-SM-3GILG GTEx Tissue Sample Gene Expression Profiles 1.0 1.00742 GTEX-TKQ1-0008-SM-4DXSO GTEx Tissue Sample Gene Expression Profiles 1.0 1.08248 STK31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27746 Intestinal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.124 GSE115542_5_v_1_digoxin_human RummaGEO Drug Perturbation Signatures -1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948085 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEF2A ENCODE Transcription Factor Targets 1.0 null GTEX-SIU8-0226-SM-2XCDS GTEx Tissue Sample Gene Expression Profiles 1.0 0.970349 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16693 LRRC59 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.54901 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.48432 A-CA-04-2009(H1N1)_7Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.83811 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.2428 hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04917 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.74269 GSE107505_0_v_2_nanog_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE158834_10_v_4_palm_human RummaGEO Gene Perturbation Signatures 1.0 null RELA ENCODE Transcription Factor Targets 1.0 null GTEX-X638-0008-SM-47JZ7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.982535 GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles 1.0 0.839495 H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r8 part of linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70452 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQW-1226-SM-2S1Q9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.877197 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.05012 EGR1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26102 EIF3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6001 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.932044 NCIH650 CCLE Cell Line Gene Expression Profiles 1.0 1.60333 GABPA_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLEKHG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57965 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3593 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K9ac_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TACO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50149 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POU5F1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08584 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.287 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MKN7 CCLE Cell Line Gene CNV Profiles 1.0 1.49187 layer III of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.80699 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.75577 Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08695 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.6851 GTEX-PWOO-2526-SM-2S1PG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 496100384_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.51141 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.962778 Nucleus ambiguus, ventral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77867 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PLXNB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.674 intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14548 p3 portion of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71234 striatum_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857145 POU6F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.13804 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-3161 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.31518 GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54251 MSI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45606 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.306567 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-1326-SM-3NB1H GTEx Tissue Sample Gene Expression Profiles 1.0 1.00607 GTEX-QLQW-1426-SM-2S1QU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ZSCAN23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28891 GDI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.65377 TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 lymph node HPA Tissue Protein Expression Profiles -1.0 -0.856547 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.04837 ventrolateral preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04958 GSE85880,GSE85881_4_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures -1.0 null CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KIAA0753 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38255 HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.12289 GTEX-QEG4-0526-SM-48TZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ING4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66328 GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 PRRC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38147 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EPHB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30507 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.79426 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null icSARS CoV_60Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.20751 mantle zone of m2ADL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27074 superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34934 H3K36me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63003 VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Basal plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.088 GTEX-R53T-1626-SM-3GAEW GTEx Tissue Sample Gene Expression Profiles 1.0 1.36198 GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11333 paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21723 COLO668 CCLE Cell Line Gene Expression Profiles 1.0 1.35276 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18887 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.14084 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02246 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDC42BPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16723 GTEX-POYW-1226-SM-2XCEP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG5-0426-SM-2I5GJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Z8-0126-SM-4GICC GTEx Tissue Sample Gene Expression Profiles 1.0 1.11209 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03769 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07198 RBBP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51396 RALY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41812 DNAJB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16232 EBF1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11204 SOX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.21902 GRANTA519 CCLE Cell Line Gene CNV Profiles -1.0 -1.73063 CL-40 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null MCIDAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28201 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-548d-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4699-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Ventral medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17515 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null GTEX-XLM4-2026-SM-4AT4X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.28569 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TML8-1426-SM-4DXUT GTEx Tissue Sample Gene Expression Profiles 1.0 0.85399 KAP1-22055183-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-2426-SM-3NMAA GTEx Tissue Sample Gene Expression Profiles 1.0 1.18248 Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-0002-SM-4LVN9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12298 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Allergic rhinitis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.40458 substance-related disorder GWASdb SNP-Disease Associations 1.0 0.124207 microbody LOCATE Predicted Protein Localization Annotations 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null Autosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.027 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.999839 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.975059 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068715 GSE86507,GSE86509_7_v_10_hoxb7_mouse RummaGEO Gene Perturbation Signatures -1.0 null NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-322-ZNF48_ZNF48 Rummagene Transcription Factor Associations 2026 1.0 null CDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3395 ZNF285 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5446 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HH CCLE Cell Line Gene Expression Profiles 1.0 2.12061 EEF1AKMT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73797 GSE214442_0_v_1_pak4_mouse RummaGEO Gene Perturbation Signatures 1.0 null reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null inner CP in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.894818 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.517271 GSE231648_1_v_5_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK1_unique_ELK1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S95S-0002-SM-3NM8K GTEx Tissue Sample Gene Expression Profiles 1.0 1.2995 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92836 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PORCN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02534 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Body mass index x age interaction GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.552288 CDK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58298 H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Anterior hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05803 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34853 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.90979 Ventral posterolateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51874 PK-45H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68898 RCM-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.76909 H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.829972 TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_8_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null BATF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.8004 Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.9279 GSE183251_7_v_6_cyp2c70_mouse RummaGEO Gene Perturbation Signatures 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null TOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56106 NIX_Deficiency_GDS2630_655_mouse_Spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HCC2279 CCLE Cell Line Gene CNV Profiles 1.0 1.52475 GFI1B ChEA Transcription Factor Targets 1.0 null H3-3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49763 HS939-T COSMIC Cell Line Gene Mutation Profiles 1.0 null MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.55705 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837498 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 0.954651 ZIK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29788 GTEX-OOBJ-0008-SM-3NB26 GTEx Tissue Sample Gene Expression Profiles 1.0 0.920621 NEUROG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44755 GAMG CCLE Cell Line Gene Expression Profiles 1.0 1.91024 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.86596 thyroid gland HPA Tissue Gene Expression Profiles 1.0 1.40663 Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE133213_6_v_13_znrf3_mouse RummaGEO Gene Perturbation Signatures -1.0 null NFIC_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5102 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12692 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.24649 H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF699 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45142 LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RTCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94591 BL5883 (CIZ1) NURSA Protein Complexes 1.0 null GTEX-PLZ6-1426-SM-2S1OQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 orbital frontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08501 GSE231799_2_v_4_nfkbie_mouse RummaGEO Gene Perturbation Signatures -1.0 null MBIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1744 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17341 FXYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90273 UBE2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39395 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-339-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 JURKAT, CLONE E6-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.916355 GPR153 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82721 GTEX-T5JC-0001-SM-3NMAK GTEx Tissue Sample Gene Expression Profiles 1.0 1.28656 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.06215 mantle zone of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46799 ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null nucleus sagulum, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89421 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.73643 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO205 DepMap CRISPR Gene Dependency 1.0 4.44332 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null SIK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62236 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TMK1 DepMap CRISPR Gene Dependency 1.0 2.79459 KMS-12-BM COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AKT1_druginhibition_81_GSE26290 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.74466 GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00905 Mathematical Ability DisGeNET Gene-Phenotype Associations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM50A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84378 GAP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78409 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 EGR1 ENCODE Transcription Factor Targets 1.0 null C2BBE1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31046 GTEX-SNOS-0003-SM-3NMAO GTEx Tissue Sample Gene Expression Profiles 1.0 1.12366 MYEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.94728 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52497 DAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53379 REC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22954 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.46301 GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37421 TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.53346 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95837 JHH2 CCLE Cell Line Gene CNV Profiles 1.0 1.35166 PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF Rummagene Transcription Factor Associations 2026 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE193258,GSE193259_2_v_4_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null Bed nuclei of the stria terminalis, posterior division, principal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98256 GSE231648_4_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45814 SOX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5679 TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RH30 CCLE Cell Line Gene CNV Profiles 1.0 1.50198 p1 part of parabrachial pigmented nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06746 outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44278 GATA6-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.187 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10458 hsa-miR-600 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95358 POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null NIPSNAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96275 PML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47101 TCF7L2 ENCODE Transcription Factor Targets 1.0 null GLRX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24258 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7254-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A375SKINCJ3 DepMap CRISPR Gene Dependency 1.0 3.02251 GTEX-WH7G-1126-SM-3NMBK GTEx Tissue Sample Gene Expression Profiles 1.0 0.88207 GATA1_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 motor nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20762 KP-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null U118MG CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BICR31 CCLE Cell Line Gene CNV Profiles -1.0 -1.80554 PPARG-20887899-3T3-L1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HIBADH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83565 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10699 TP63_01_200 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59277 POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55G-1626-SM-48FF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGIF2LX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0459 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.6948 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SCCPDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62509 SALL4-22934838-CD34+-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ABL1_druginhibition_77_GSE24493 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.08254 H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NDUFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0536 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.14428 GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles 1.0 0.979476 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE122215,GSE122217_5_v_1_peg10_mouse RummaGEO Gene Perturbation Signatures 1.0 null EGR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLSPN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45041 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3924 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KPNYN CCLE Cell Line Gene CNV Profiles -1.0 -1.94468 NFATC1 ENCODE Transcription Factor Targets 1.0 null polymorphic layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20116 ARL8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3537 NIX_Deficiency_GDS2630_160_mouse_spleen GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12326 HTR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16234 TAF1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14416 ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-0526-SM-4LVLY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNS81 DepMap CRISPR Gene Dependency 1.0 3.54085 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.68215 TCF3 ENCODE Transcription Factor Targets 1.0 null GSE136622_7_v_3_srpk3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A4XF-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPRTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15808 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54571 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14309 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.69293 H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25454 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07287 NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null HBA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54714 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1568 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r8 portion of ambiguous motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.56743 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null CNST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50505 peroxisome LOCATE Predicted Protein Localization Annotations 1.0 null GSE231648_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 ISX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81371 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.61173 ELK4_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZN-1826-SM-4DXUY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26C-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null horizontal nucleus of the diagonal band, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58457 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.0492 Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03584 ERAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14922 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterobasal nucleus, intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28437 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.01154 r8 part of lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01874 PAGE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45006 Peripheral_Blood_Mononuclear_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.11426 PCGF4-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null MTCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.39511 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null XRCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40648 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46376 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.888296 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.13756 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAB11FIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2201 GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00544 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37602 RERFLCKJ CCLE Cell Line Gene CNV Profiles 1.0 1.83465 PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.04703 NTERA-2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.438 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07409 TGFBR2_knockout_292_GSE46150 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.6407 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07104 VDAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98893 INPP5F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.93482 CAL-72 COSMIC Cell Line Gene CNV Profiles 1.0 2.1316 SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55694 GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 TUBGCP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10734 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null POLR3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75894 PLEKHH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15489 Nucleus solitarius TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.533 GTEX-O5YW-1826-SM-2YUN2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCNK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95026 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60329 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-0005-SM-2TC5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.997005 cognitive disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.052255 DBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2331 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SALL4 ChEA Transcription Factor Targets 1.0 null JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF385B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6281 CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIAH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56138 KRT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87305 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.82009 ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9667 H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QLQW-0726-SM-447AA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 COLO-824 COSMIC Cell Line Gene CNV Profiles 1.0 2.1316 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87141 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.886366 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.73394 JAR COSMIC Cell Line Gene Mutation Profiles 1.0 null UTP14C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49516 BRD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55349 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.16697 DMS153 CCLE Cell Line Gene CNV Profiles 1.0 1.81379 GPATCH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74828 skmel30 HPA Cell Line Gene Expression Profiles 1.0 1.53149 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.12595 hsa-miR-496 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.85415 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41946 AIDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34547 GTEX-TSE9-2826-SM-4DXTF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE190761_0_v_1_samd1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DUSP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48641 hsa-miR-4711-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.389112 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-2226-SM-2XCAQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.63876 HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5379 GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 atherosclerosis GWASdb SNP-Disease Associations 1.0 0.886521 OV7 DepMap CRISPR Gene Dependency 1.0 4.52895 GTEX-XUJ4-1526-SM-4BONU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAS1 DepMap CRISPR Gene Dependency 1.0 2.21907 superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4892 RS411 CCLE Cell Line Gene Mutation Profiles 1.0 null ASB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80041 ZFP90 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4276 RANBP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17834 PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CIR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35576 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4226 GSE223609,GSE223610_0_v_1_kdm6a_human RummaGEO Gene Perturbation Signatures 1.0 null COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.906779 GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles 1.0 0.971645 MDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76759 anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.20761 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null CACO-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.859137 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61917 ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null orofacial cleft GWASdb SNP-Disease Associations 1.0 0.686153 vagina HPA Tissue Protein Expression Profiles -1.0 -0.856547 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.45491 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63757 GTEX-V1D1-0526-SM-4JBGW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.878397 GSE187006_3_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null SPIN2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24861 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.4466 GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.39514 PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIPA1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73039 p1Lim part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16861 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.01321 Perturb_460_KD_CCR3_SRP220486 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15777 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDX60L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13526 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZFAND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57956 BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.27374 H2AC25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83727 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 2.02638 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null thyroid_5c HPA Tissue Sample Gene Expression Profiles 1.0 0.889825 GSE174498,GSE174500_2_v_1_asparaginase_human RummaGEO Drug Perturbation Signatures 1.0 null HT-55 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28824 CREB1 ChEA Transcription Factor Targets 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE159893_2_v_0_genistein_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of r7Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06759 POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null 18338247-SuppTable4A GeneSigDB Published Gene Signatures 1.0 null MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877963 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78719 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LCAT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28264 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44046 BATF::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9565 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.39217 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52959 LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes (MG-430B) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SLC22A31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08684 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4635-01A-02R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40371 GTEX-OHPK-2626-SM-2HMK9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05272 BRCA1 ENCODE Transcription Factor Targets 1.0 null THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.901301 COL6A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40783 Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40181 Rge TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.553 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0826-SM-4BRWG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE240386,GSE242143_8_v_6_morc2_human RummaGEO Gene Perturbation Signatures 1.0 null NFYA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.62406 GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures 1.0 null H3K79me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3Q0-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Teratocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.876 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NUAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24952 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-2426-SM-48FF5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03913 Membrane COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.774 r8 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06319 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r9 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39145 H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2039 BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88109 NCIH2452 CCLE Cell Line Gene CNV Profiles -1.0 -1.41411 CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8257-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.92809 Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLI1 ENCODE Transcription Factor Targets 1.0 null H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.886377 ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 Hypertrophy CTD Gene-Disease Associations 1.0 1.0608 MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 hsa-miR-21 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE131649_4_v_11_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null NDUFS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22883 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB361 DepMap CRISPR Gene Dependency 1.0 4.90152 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14098 GTEX-QDVJ-0726-SM-48U1W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BATF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2513 Claustrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.551 SYF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29915 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.5134 RL CCLE Cell Line Gene CNV Profiles 1.0 2.33619 primary motor cortex (area M1, area 4)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.26276 LN319 CCLE Cell Line Gene Expression Profiles -1.0 -1.48165 GSE95077_5_v_0_amiloride_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 KMM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837498 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null uterus GTEx Tissue Gene Expression Profiles -1.0 -0.957413 PFSK1 DepMap CRISPR Gene Dependency 1.0 2.56432 mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35746 SERPINB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0076 GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 NCI-H1355 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 JUND_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-0011-R9A-SM-3MJFP GTEx Tissue Sample Gene Expression Profiles 1.0 0.940269 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.873235 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6225 DCLRE1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80273 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SNTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21893 GTEX-SIU8-0526-SM-2XCDP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14842 mantle zone of r7Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10201 CAPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24036 NELFE ENCODE Transcription Factor Targets 1.0 null ZNF93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7929 EGR1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPT6-0001-SM-4B64G GTEx Tissue Sample Gene Expression Profiles 1.0 1.02697 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.90949 large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308974 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41274 H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MED28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96327 MRPL35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88123 GSE149123,GSE149128_2_v_0_cdk7_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-IRF1_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null LS 180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00308 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AD-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.837498 NCI-H2030 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.880003 GATM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.34991 ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null